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Phosphoinositide 3‐kinase/Akt pathway plays an important role in chemoresistance of gastric cancer cells against etoposide and doxorubicin induced cell death

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/cncr.11660openalex-snapshot

Histomorphology and grading of regression in gastric carcinoma treated with neoadjuvant chemotherapy

inferredcites →https://doi.org/10.1002/ijc.10962openalex-snapshot

Frequent monoallelic deletion of PTEN and its reciprocal associatioin with PIK3CA amplification in gastric carcinoma

inferredcites →https://doi.org/10.1002/ijc.21170openalex-snapshot

Akt phosphorylation associates with LOH of PTEN and leads to chemoresistance for gastric cancer

inferredcites →https://doi.org/10.1006/bbrc.1995.2654openalex-snapshot

Molecular Cloning and Characterization of a New Member of the RAC Protein Kinase Family: Association of the Pleckstrin Homology Domain of 3 Types of RAC Protein Kinase with Protein Kinase C Subspecies and βγ Subunits of G Proteins

inferredcites →https://doi.org/10.1007/s00432-003-0505-zopenalex-snapshot

Inhibition of the PI3K-Akt signaling pathway enhances the sensitivity of Fas-mediated apoptosis in human gastric carcinoma cell line, MKN-45

inferredcites →https://doi.org/10.1016/0092-8674(95)90534-0openalex-snapshot

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

inferredcites →https://doi.org/10.1016/j.canlet.2004.11.021openalex-snapshot

Upregulated Akt signaling adjacent to gastric cancers: implications for screening and chemoprevention

inferredcites →https://doi.org/10.1016/j.canlet.2004.12.006openalex-snapshot

Genetic mutual relationship between PTEN and p53 in gastric cancer

inferredcites →https://doi.org/10.1016/j.ccr.2005.09.006openalex-snapshot

The BAD protein integrates survival signaling by EGFR/MAPK and PI3K/Akt kinase pathways in PTEN-deficient tumor cells

inferredcites →https://doi.org/10.1016/j.jamcollsurg.2004.04.015openalex-snapshot

Inducible nuclear factor-κB activation contributes to chemotherapy resistance in gastric cancer1

inferredcites →https://doi.org/10.1016/s0014-5793(98)01109-0openalex-snapshot

The promoter of human p22/PACAP response gene 1 (PRG1) contains functional binding sites for the p53 tumor suppressor and for NFκB

inferredcites →https://doi.org/10.1016/s0167-4781(98)00134-1openalex-snapshot

Clinical applications of anticancer drugs targeted to topoisomerase II

inferredcites →https://doi.org/10.1038/35019154openalex-snapshot

Kinase regulation in inflammatory response

inferredcites →https://doi.org/10.1038/35099574openalex-snapshot

Forkhead transcription factors contribute to execution of the mitotic programme in mammals

inferredcites →https://doi.org/10.1038/43466openalex-snapshot

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

inferredcites →https://doi.org/10.1038/43474openalex-snapshot

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

inferredcites →https://doi.org/10.1038/nature04870openalex-snapshot

Nuclear factor-κB in cancer development and progression

inferredcites →https://doi.org/10.1038/ncb1101-973openalex-snapshot

HER-2/neu induces p53 ubiquitination via Akt-mediated MDM2 phosphorylation

inferredcites →https://doi.org/10.1038/nrc839openalex-snapshot

The phosphatidylinositol 3-Kinase–AKT pathway in human cancer

inferredcites →https://doi.org/10.1038/sj.onc.1208106openalex-snapshot

Rho/Rhotekin-mediated NF-κB activation confers resistance to apoptosis

inferredcites →https://doi.org/10.1038/sj.onc.1209598openalex-snapshot

Mitochondria as therapeutic targets for cancer chemotherapy

inferredcites →https://doi.org/10.1038/sj.onc.1209608openalex-snapshot

Extrinsic versus intrinsic apoptosis pathways in anticancer chemotherapy

inferredcites →https://doi.org/10.1046/j.1523-1755.2001.00026.xopenalex-snapshot

Role and regulation of activation of caspases in cisplatin-induced injury to renal tubular epithelial cells

inferredcites →https://doi.org/10.1073/pnas.1336511100openalex-snapshot

Protein tyrosine phosphatase RQ is a phosphatidylinositol phosphatase that can regulate cell survival and proliferation

inferredcites →https://doi.org/10.1073/pnas.88.10.4171openalex-snapshot

Molecular cloning and identification of a serine/threonine protein kinase of the second-messenger subfamily.

inferredcites →https://doi.org/10.1073/pnas.89.19.9267openalex-snapshot

AKT2, a putative oncogene encoding a member of a subfamily of protein-serine/threonine kinases, is amplified in human ovarian carcinomas.

inferredcites →https://doi.org/10.1074/jbc.271.48.30835openalex-snapshot

Akt Is a Direct Target of the Phosphatidylinositol 3-Kinase

inferredcites →https://doi.org/10.1074/jbc.273.29.17999openalex-snapshot

Topoisomerase II-mediated DNA Cleavage and Religation in the Absence of Base Pairing

inferredcites →https://doi.org/10.1074/jbc.m105202200openalex-snapshot

Internalin B Activates Nuclear Factor-κB via Ras, Phosphoinositide 3-Kinase, and Akt

inferredcites →https://doi.org/10.1074/jbc.m314337200openalex-snapshot

Akt Kinase Activation Blocks Apoptosis in Intestinal Epithelial Cells by Inhibiting Caspase-3 after Polyamine Depletion

inferredcites →https://doi.org/10.1080/07357900600633924openalex-snapshot

A Phase II Study of Doxorubicin, Cisplatin, and 5-Fluorouracil in Patients with Advanced Adenocarcinoma of the Stomach or Esophagus

inferredcites →https://doi.org/10.1089/dna.2005.24.141openalex-snapshot

COX-2 Inhibitor, NS398, Enhances Fas-Mediated Apoptosis via Modulation of the PTEN–Akt Pathway in Human Gastric Carcinoma Cell Lines

inferredcites →https://doi.org/10.1091/mbc.2.12.1001openalex-snapshot

Molecular cloning of a second form of rac protein kinase.

inferredcites →https://doi.org/10.1093/jnci/91.22.1922openalex-snapshot

Mutational Spectra of PTEN/MMAC1 Gene: a Tumor Suppressor With Lipid Phosphatase Activity

inferredcites →https://doi.org/10.1101/gad.889901openalex-snapshot

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

inferredcites →https://doi.org/10.1126/science.1833819openalex-snapshot

A Retroviral Oncogene, akt , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region

inferredcites →https://doi.org/10.1126/science.282.5392.1318openalex-snapshot

Regulation of Cell Death Protease Caspase-9 by Phosphorylation

inferredcites →https://doi.org/10.1128/mcb.16.4.1722openalex-snapshot

Wortmannin Inactivates Phosphoinositide 3-Kinase by Covalent Modification of Lys-802, a Residue Involved in the Phosphate Transfer Reaction

inferredcites →https://doi.org/10.1128/mcb.20.1.139-148.2000openalex-snapshot

The Phosphoinositide 3-OH Kinase/AKT2 Pathway as a Critical Target for Farnesyltransferase Inhibitor-Induced Apoptosis

inferredcites →https://doi.org/10.1128/mcb.20.5.1626-1638.2000openalex-snapshot

Akt Suppresses Apoptosis by Stimulating the Transactivation Potential of the RelA/p65 Subunit of NF-κB

inferredcites →https://doi.org/10.1128/mcb.21.3.952-965.2001openalex-snapshot

Protein Kinase SGK Mediates Survival Signals by Phosphorylating the Forkhead Transcription Factor FKHRL1 (FOXO3a)

inferredcites →https://doi.org/10.1158/0008-5472.can-03-1860openalex-snapshot

Tumor Stroma Interactions Induce Chemoresistance in Pancreatic Ductal Carcinoma Cells Involving Increased Secretion and Paracrine Effects of Nitric Oxide and Interleukin-1β

inferredcites →https://doi.org/10.1158/0008-5472.can-04-4009openalex-snapshot

PED Mediates AKT-Dependent Chemoresistance in Human Breast Cancer Cells

inferredcites →https://doi.org/10.1158/0008-5472.can-05-0425openalex-snapshot

Akt-Mediated Cisplatin Resistance in Ovarian Cancer: Modulation of p53 Action on Caspase-Dependent Mitochondrial Death Pathway

inferredcites →https://doi.org/10.1158/0008-5472.can-05-1330openalex-snapshot

Molecular Evidence for Increased Antitumor Activity of Gemcitabine by Genistein In vitro and In vivo Using an Orthotopic Model of Pancreatic Cancer

inferredcites →https://doi.org/10.1158/0008-5472.can-05-3018openalex-snapshot

Activation of Mammalian Target of Rapamycin Signaling Pathway Contributes to Tumor Cell Survival in Anaplastic Lymphoma Kinase–Positive Anaplastic Large Cell Lymphoma

inferredcites →https://doi.org/10.1159/000080285openalex-snapshot

Long-Term Follow-Up of a Pilot Phase II Study with Neoadjuvant Epidoxorubicin, Etoposide and Cisplatin in Gastric Cancer

inferredcites →https://doi.org/10.1172/jci26273openalex-snapshot

The survival kinases Akt and Pim as potential pharmacological targets

inferredcites →https://doi.org/10.1593/neo.05745openalex-snapshot

Akt- and CREB-Mediated Prostate Cancer Cell Proliferation Inhibition by Nexrutine, a Phellodendron amurense Extract

inferredcites →https://doi.org/10.3748/wjg.v12.i2.192openalex-snapshot

Alterations of tumor suppressor and tumor-related genes in the development and progression of gastric cancer

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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The COP9 signalosome-mediated deneddylation is stimulated by caspases during apoptosis

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inferred← citeshttps://doi.org/10.1007/s13273-023-00403-9openalex-snapshot

SEC61G knockdown enhances the sensitivity of gastric cancer cells to etoposide through EGFR and glycolytic-mediated pathways

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Arsenic trioxide induces apoptosis and G2/M phase arrest by inducing Cbl to inhibit PI3K/Akt signaling and thereby regulate p53 activation

inferred← citeshttps://doi.org/10.1016/j.canlet.2010.02.011openalex-snapshot

Concurrent blockade of the NF-κB and Akt pathways potently sensitizes cancer cells to chemotherapeutic-induced cytotoxicity

inferred← citeshttps://doi.org/10.1016/j.canlet.2011.02.001openalex-snapshot

FHL2 exhibits anti-proliferative and anti-apoptotic activities in liver cancer cells

inferred← citeshttps://doi.org/10.1016/j.celrep.2021.109854openalex-snapshot

RNF8-mediated regulation of Akt promotes lung cancer cell survival and resistance to DNA damage

inferred← citeshttps://doi.org/10.1016/j.clinbiochem.2013.10.014openalex-snapshot

Concomitant PIK3CA amplification and RASSF1A or PAX6 hypermethylation predict worse survival in gastric cancer

inferred← citeshttps://doi.org/10.1016/j.colsurfb.2016.05.043openalex-snapshot

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Combination of microtubule associated protein-tau and β-tubulin III predicts chemosensitivity of paclitaxel in patients with advanced gastric cancer

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Inhibition of doxorubicin‐induced HER3‐PI3K‐AKT signalling enhances apoptosis of ovarian cancer cells

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MiR-26a performs converse roles in proliferation and metastasis of different gastric cancer cells via regulating of PTEN expression

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RNAi knockdown of the Akt1 gene increases the chemosensitivity of gastric cancer cells to cisplatin both in vitro and in vivo

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miR-21 confers cisplatin resistance in gastric cancer cells by regulating PTEN

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Induction of Akt Activity by Chemotherapy Confers Acquired Resistance

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Human oncoprotein MDM2 activates the Akt signaling pathway through an interaction with the repressor element-1 silencing transcription factor conferring a survival advantage to cancer cells

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The AKT1/NF-kappaB/Notch1/PTEN axis has an important role in chemoresistance of gastric cancer cells

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α-Actinin-4 promotes metastasis in gastric cancer

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MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway

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MicroRNA-21 induces resistance to the anti-tumour effect of interferon-α/5-fluorouracil in hepatocellular carcinoma cells

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Histone H4 expression is cooperatively maintained by IKKβ and Akt1 which attenuates cisplatin-induced apoptosis through the DNA-PK/RIP1/IAPs signaling cascade

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The forkhead transcription factor FOXO4 sensitizes cancer cells to doxorubicin-mediated cytotoxicity

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Anticancer potential of (−)-epicatechin in a triple-negative mammary gland model

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Genome rearrangements induced by the stimulation of end-joining of DNA double strand breaks through multiple phosphorylation of MRE11 by the kinase PKB/AKT1

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Annexin A1 induces oxaliplatin resistance of gastric cancer through autophagy by targeting PI3K/AKT/mTOR

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Concurrent blockade of NF-κB and Akt pathways potentiates cisplatin’s antitumor activity in vivo

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Identifying “Many-to-Many” Relationships between Gene-Expression Data and Drug-Response Data via Sparse Binary Matching

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Downregulation of leucine‐rich repeats and immunoglobulin‐like domains 1 by micro RNA ‐20a modulates gastric cancer multidrug resistance

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Liver–intestine cadherin induction by epidermal growth factor receptor is associated with intestinal differentiation of gastric cancer

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Low-dose taxotere enhances the ability of sorafenib to induce apoptosis in gastric cancer models

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Activation of Nuclear Factor-κB Pathway by Simvastatin and RhoA Silencing Increases Doxorubicin Cytotoxicity in Human Colon Cancer HT29 Cells

inferred← citeshttps://doi.org/10.1126/science.1175065openalex-snapshot

The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation

inferred← citeshttps://doi.org/10.1126/scitranslmed.3000630openalex-snapshot

Nuclear Phospho-Akt Increase Predicts Synergy of PI3K Inhibition and Doxorubicin in Breast and Ovarian Cancer

inferred← citeshttps://doi.org/10.1155/2015/124721openalex-snapshot

Protecting Intestinal Epithelial Cell Number 6 against Fission Neutron Irradiation through NF-κB Signaling Pathway

inferred← citeshttps://doi.org/10.1155/2020/6358685openalex-snapshot

MAC30 Knockdown Inhibits Proliferation and Enhance Apoptosis of Gastric Cancer by Suppressing Wnt/β-Cateninsignaling Pathway

inferred← citeshttps://doi.org/10.1155/2023/8268955openalex-snapshot

3,3′-Diindolylmethane Augments 5-Fluorouracil-InducedGrowth Suppression in Gastric Cancer Cells through Suppression of the Akt/GSK-3β and WNT/Beta-Catenin

inferred← citeshttps://doi.org/10.1158/0008-5472.can-09-2777openalex-snapshot

MicroRNA-375 Is Downregulated in Gastric Carcinomas and Regulates Cell Survival by Targeting PDK1 and 14-3-3ζ

inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-08-0385openalex-snapshot

Targeting the PI3K p110α Isoform Inhibits Medulloblastoma Proliferation, Chemoresistance, and Migration

inferred← citeshttps://doi.org/10.1158/1535-7163.mct-12-0342openalex-snapshot

Cell Intrinsic Role of COX-2 in Pancreatic Cancer Development

inferred← citeshttps://doi.org/10.1158/1535-7163.mct-17-0325openalex-snapshot

Combinatorial Treatment with mTOR Inhibitors and Streptozotocin Leads to Synergistic In Vitro and In Vivo Antitumor Effects in Insulinoma Cells

inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-10-0114openalex-snapshot

CADPE Inhibits PMA-Stimulated Gastric Carcinoma Cell Invasion and Matrix Metalloproteinase-9 Expression by FAK/MEK/ERK–Mediated AP-1 Activation

inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-10-0200openalex-snapshot

A Sensitized RNA Interference Screen Identifies a Novel Role for the PI3K p110γ Isoform in Medulloblastoma Cell Proliferation and Chemoresistance

inferred← citeshttps://doi.org/10.1158/1541-7786.mcr-17-0593openalex-snapshot

PI3K Positively Regulates YAP and TAZ in Mammary Tumorigenesis Through Multiple Signaling Pathways

inferred← citeshttps://doi.org/10.1167/iovs.61.10.9openalex-snapshot

microRNA-222-Mediated VHL Downregulation Facilitates Retinoblastoma Chemoresistance by Increasing HIF1α Expression

inferred← citeshttps://doi.org/10.1172/jci.insight.99327openalex-snapshot

The mutational landscape of recurrent versus nonrecurrent human papillomavirus–related oropharyngeal cancer

inferred← citeshttps://doi.org/10.1177/030006051204000610openalex-snapshot

Protein Kinase B Phosphorylation Correlates with Vascular Endothelial Growth Factor A and Microvessel Density in Gastric Adenocarcinoma

inferred← citeshttps://doi.org/10.1177/039463201202500309openalex-snapshot

Exression and PI3K/AKT Pathway in Gastric Cancer and its Blockade Suppresses Tumor Growth and Metastasis

inferred← citeshttps://doi.org/10.1186/1471-2407-10-367openalex-snapshot

MicroRNA-221 and microRNA-222 regulate gastric carcinoma cell proliferation and radioresistance by targeting PTEN

inferred← citeshttps://doi.org/10.1186/1471-2407-12-50openalex-snapshot

Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer

inferred← citeshttps://doi.org/10.1186/s12906-019-2725-zopenalex-snapshot

Coix lacryma-jobi var. ma-yuen Stapf sprout extract induces cell cycle arrest and apoptosis in human cervical carcinoma cells

inferred← citeshttps://doi.org/10.1186/s12935-021-01941-9openalex-snapshot

Exosomal microRNAs in hepatocellular carcinoma

inferred← citeshttps://doi.org/10.1186/s12935-025-04004-5openalex-snapshot

Exploring the role of miR-221/222 in gastrointestinal cancers: implications for innovative therapeutic strategies

inferred← citeshttps://doi.org/10.1186/s12943-019-0969-3openalex-snapshot

Circular RNA AKT3 upregulates PIK3R1 to enhance cisplatin resistance in gastric cancer via miR-198 suppression

inferred← citeshttps://doi.org/10.1186/s13046-018-0677-7openalex-snapshot

RETRACTED ARTICLE: Exosomal microRNA-32-5p induces multidrug resistance in hepatocellular carcinoma via the PI3K/Akt pathway

inferred← citeshttps://doi.org/10.1186/s40360-020-00442-1openalex-snapshot

Boswellic acid sensitizes gastric cancer cells to Cisplatin-induced apoptosis via p53-mediated pathway

inferred← citeshttps://doi.org/10.1186/s41021-021-00192-4openalex-snapshot

MicroRNAs as the critical regulators of cisplatin resistance in gastric tumor cells

inferred← citeshttps://doi.org/10.1186/s43556-022-00110-2openalex-snapshot

Targeting the PI3K/AKT/mTOR and RAF/MEK/ERK pathways for cancer therapy

inferred← citeshttps://doi.org/10.1245/s10434-013-3146-8openalex-snapshot

Significance of mTOR Signaling and Its Inhibitor Against Cancer Stem-Like Cells in Colorectal Cancer

inferred← citeshttps://doi.org/10.13040/ijpsr.0975-8232.6(12).4920-39openalex-snapshot

inferred← citeshttps://doi.org/10.1371/journal.pone.0004070openalex-snapshot

Akt Regulates Drug-Induced Cell Death through Bcl-w Downregulation

inferred← citeshttps://doi.org/10.1371/journal.pone.0123958openalex-snapshot

The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma

inferred← citeshttps://doi.org/10.1371/journal.pone.0245876openalex-snapshot

The high expression of NUDT5 indicates poor prognosis of breast cancer by modulating AKT / Cyclin D signaling

inferred← citeshttps://doi.org/10.1515/hmbci.2010.063openalex-snapshot

Cancer protection of soy resembles cancer protection during pregnancy

inferred← citeshttps://doi.org/10.1517/14728214.2013.805203openalex-snapshot

Emerging tyrosine kinase inhibitors for esophageal cancer

inferred← citeshttps://doi.org/10.15406/ppij.2024.12.00446openalex-snapshot

Mechanotransduction alterations in tissue-engineered tumor models for new drug interventions

inferred← citeshttps://doi.org/10.15557/cgo.2014.0017openalex-snapshot

siRNA preparations in gene therapy of ovarian cancer

inferred← citeshttps://doi.org/10.18632/oncotarget.19048openalex-snapshot

The molecular mechanisms of chemoresistance in cancers

inferred← citeshttps://doi.org/10.18632/oncotarget.3633openalex-snapshot

Endogenous molecular network reveals two mechanisms of heterogeneity within gastric cancer

inferred← citeshttps://doi.org/10.18632/oncotarget.4990openalex-snapshot

Molecular classification of gastric cancer: Towards a pathway-driven targeted therapy

inferred← citeshttps://doi.org/10.21203/rs.3.rs-117480/v1openalex-snapshot

Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting PI3K/AKT Pathway and Activating AMPK/ROS Pathway

inferred← citeshttps://doi.org/10.2147/dddt.s360790openalex-snapshot

Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer

inferred← citeshttps://doi.org/10.2147/ott.s239336openalex-snapshot

A Review of Research Progress in Multidrug-Resistance Mechanisms in Gastric Cancer

inferred← citeshttps://doi.org/10.2147/ott.s25117openalex-snapshot

Targeted therapy for esophagogastric cancers: a review

inferred← citeshttps://doi.org/10.2174/138161210789941865openalex-snapshot

The PKB/AKT Pathway in Cancer

inferred← citeshttps://doi.org/10.21873/anticanres.12588openalex-snapshot

Multimodal Anti-tumor Approaches Combined with Immunotherapy to Overcome Tumor Resistance in Esophageal and Gastric Cancer

inferred← citeshttps://doi.org/10.2217/fon.10.21openalex-snapshot

New Insights into the Mechanisms of Gastric Cancer Multidrug Resistance and Future Perspectives

inferred← citeshttps://doi.org/10.2217/nnm.13.54openalex-snapshot

Development of Chitosan/Heparin Nanoparticle-Encapsulated Cytolethal Distending Toxin for Gastric Cancer Therapy

inferred← citeshttps://doi.org/10.3109/07388551.2015.1015957openalex-snapshot

Molecular mechanisms of drug resistance and its reversal in cancer

inferred← citeshttps://doi.org/10.3109/10428194.2013.811579openalex-snapshot

Rapamycin interacts synergistically with idarubicin to induce T-leukemia cell apoptosisin vitroand in a mesenchymal stem cell simulated drug-resistant microenvironment via Akt/mammalian target of rapamycin and extracellular signal-related kinase signaling pathways

inferred← citeshttps://doi.org/10.33590/emj/10313567openalex-snapshot

Editor’s Pick: Pyruvate Kinase and Gastric Cancer: A Potential Marker

inferred← citeshttps://doi.org/10.3389/fcell.2021.661602openalex-snapshot

Exosomal miR-92b-3p Promotes Chemoresistance of Small Cell Lung Cancer Through the PTEN/AKT Pathway

inferred← citeshttps://doi.org/10.3389/fonc.2013.00093openalex-snapshot

Dissecting the PI3K Signaling Axis in Pediatric Solid Tumors: Novel Targets for Clinical Integration

inferred← citeshttps://doi.org/10.3389/fonc.2021.642229openalex-snapshot

Targeting ACLY Attenuates Tumor Growth and Acquired Cisplatin Resistance in Ovarian Cancer by Inhibiting the PI3K–AKT Pathway and Activating the AMPK–ROS Pathway

inferred← citeshttps://doi.org/10.3390/cancers10120482openalex-snapshot

Differing Roles of Hyaluronan Molecular Weight on Cancer Cell Behavior and Chemotherapy Resistance

inferred← citeshttps://doi.org/10.3390/cancers15235500openalex-snapshot

Regulation of Vascular Endothelial Growth Factor Signaling by Nicotine in a Manner Dependent on Acetylcholine-and/or β-Adrenergic-Receptors in Human Lung Cancer Cells

inferred← citeshttps://doi.org/10.3390/cancers6031441openalex-snapshot

The Role of PI3K/Akt/mTOR Signaling in Gastric Carcinoma

inferred← citeshttps://doi.org/10.3390/cells12030405openalex-snapshot

Phosphorylation of IGFBP-3 by Casein Kinase 2 Blocks Its Interaction with Hyaluronan, Enabling HA-CD44 Signaling Leading to Increased NSCLC Cell Survival and Cisplatin Resistance

inferred← citeshttps://doi.org/10.3390/ijms19061683openalex-snapshot

Proposed Molecular and miRNA Classification of Gastric Cancer

inferred← citeshttps://doi.org/10.3390/ijms24032809openalex-snapshot

Interfering with the Ubiquitin-Mediated Regulation of Akt as a Strategy for Cancer Treatment

inferred← citeshttps://doi.org/10.3390/ijms25052755openalex-snapshot

Synergy between PEDF and Doxorubicin in Breast Cancer Cells: Effects on Metastatic and Metabolic Pathways

inferred← citeshttps://doi.org/10.3390/molecules23010042openalex-snapshot

Fascaplysin Sensitizes Anti-Cancer Effects of Drugs Targeting AKT and AMPK

inferred← citeshttps://doi.org/10.3390/nu10121829openalex-snapshot

Nobiletin Enhances Chemosensitivity to Adriamycin through Modulation of the Akt/GSK3β/β–Catenin/MYCN/MRP1 Signaling Pathway in A549 Human Non-Small-Cell Lung Cancer Cells

inferred← citeshttps://doi.org/10.3748/wjg.v17.i2.181openalex-snapshot

LY294002 potentiates the anti-cancer effect of oxaliplatin for gastric cancerviadeath receptor pathway

inferred← citeshttps://doi.org/10.3748/wjg.v18.i26.3458openalex-snapshot

Phosphoinositide-3-kinase, catalytic, alpha polypeptide RNA interference inhibits growth of colon cancer cell SW948

inferred← citeshttps://doi.org/10.3748/wjg.v18.i48.7262openalex-snapshot

Notch2 regulates matrix metallopeptidase 9viaPI3K/AKT signaling in human gastric carcinoma cell MKN-45

inferred← citeshttps://doi.org/10.3748/wjg.v20.i38.13804openalex-snapshot

Pathogenetic mechanisms in gastric cancer

inferred← citeshttps://doi.org/10.3748/wjg.v22.i20.4812openalex-snapshot

Current and emerging therapies in unresectable and recurrent gastric cancer

inferred← citeshttps://doi.org/10.3748/wjg.v22.i30.6776openalex-snapshot

New advances in targeted gastric cancer treatment

inferred← citeshttps://doi.org/10.3892/ijmm.2019.4070openalex-snapshot

miR‑16‑2‑3p inhibits cell proliferation and migration and induces apoptosis by targeting PDPK1 in�maxillary primordium mesenchymal cells

inferred← citeshttps://doi.org/10.3892/ijo.2015.2890openalex-snapshot

Myeloid cell leukemia-1 regulates the cell growth and predicts prognosis in gastric cancer

inferred← citeshttps://doi.org/10.3892/ijo.2018.4314openalex-snapshot

Lemongrass essential oil and citral inhibit Src/Stat3 activity and suppress the proliferation/survival of small-cell lung cancer cells, alone or in combination with chemotherapeutic agents

inferred← citeshttps://doi.org/10.3892/ijo_00000195openalex-snapshot

Synergistic cell growth inhibition by the combination of amrubicin and Akt-suppressing tyrosine kinase inhibitors in small cell lung cancer cells: Implication of c-Src and its inhibitor

inferred← citeshttps://doi.org/10.3892/ijo_00000246openalex-snapshot

Overexpression of eukaryotic elongation factor eEF2 in gastrointestinal cancers and its involvement in G2/M progression in the cell cycle

inferred← citeshttps://doi.org/10.3892/mmr.2013.1554openalex-snapshot

Activation of the p38 MAPK/NF-κB pathway contributes to doxorubicin-induced inflammation and cytotoxicity in H9c2 cardiac cells

inferred← citeshttps://doi.org/10.3892/mmr.2014.2617openalex-snapshot

LY294002 suppresses the malignant phenotype and sensitizes osteosarcoma cells to pirarubicin chemotherapy

inferred← citeshttps://doi.org/10.3892/mmr.2020.10936openalex-snapshot

Low‑intensity ultrasound enhances the antitumor effects of doxorubicin on hepatocellular carcinoma cells through the ROS‑miR‑21‑PTEN axis

inferred← citeshttps://doi.org/10.3892/mmr.2021.12142openalex-snapshot

lncRNA NEAT1 regulates gastric carcinoma cell proliferation, invasion and apoptosis via the miR‑500a‑3p/XBP‑1 axis

inferred← citeshttps://doi.org/10.3892/mmr_00000309openalex-snapshot

Activation of the PI3K/Akt and MAPK signaling pathways antagonizes adriamycin-induced HL-60 leukemia cell apoptosis

inferred← citeshttps://doi.org/10.3892/ol.2013.1132openalex-snapshot

Regulation of AKT gene expression by cisplatin

inferred← citeshttps://doi.org/10.3892/ol.2014.2514openalex-snapshot

Involvement of the Akt signaling pathway in ER-α36/GRP94-mediated signaling in gastric cancer

inferred← citeshttps://doi.org/10.3892/ol.2017.7112openalex-snapshot

Combination of cecropinXJ and LY294002 induces synergistic cytotoxicity, and apoptosis in human gastric cancer cells via inhibition of the PI3K/Akt signaling pathway

inferred← citeshttps://doi.org/10.3892/ol.2017.7693openalex-snapshot

Interference of P-REX2a may inhibit proliferation and reverse the resistance of SGC7901 cells to doxorubicin

inferred← citeshttps://doi.org/10.3892/ol.2018.8587openalex-snapshot

PI3K/AKT inhibition induces compensatory activation of the MET/STAT3 pathway in non‑small cell lung cancer

inferred← citeshttps://doi.org/10.3892/ol.2018.9039openalex-snapshot

Doxorubicin combined with Notch1‑targeting siRNA for the treatment of gastric cancer

inferred← citeshttps://doi.org/10.3892/or.2010.957openalex-snapshot

Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer

inferred← citeshttps://doi.org/10.3892/or.2013.2695openalex-snapshot

Adenovirus-mediated IL-24 expression enhances the chemosensitivity of multidrug-resistant gastric cancer cells to cisplatin

inferred← citeshttps://doi.org/10.3892/or.2017.5533openalex-snapshot

Induction of galectin-1 by TLR-dependent PI3K activation enhances epithelial-mesenchymal transition of metastatic ovarian cancer cells

inferred← citeshttps://doi.org/10.3892/or_00000558openalex-snapshot

Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells

inferred← citeshttps://doi.org/10.3892/or_00000832openalex-snapshot

Mutation analysis of tumor suppressor gene PTEN in patients with gastric carcinomas and its impact on PI3K/AKT pathway

inferred← citeshttps://doi.org/10.3978/j.issn.2078-6891.2014.098openalex-snapshot

Current status of novel agents in advanced gastroesophageal adenocarcinoma.

inferred← citeshttps://doi.org/10.4149/304_150806n433openalex-snapshot

Reversal of cisplatin resistance by inhibiting PI3K/Akt signal pathway in human lung cancer cells

inferred← citeshttps://doi.org/10.4161/cc.10.21.17895openalex-snapshot

Caveolin-1 promotes pancreatic cancer cell differentiation and restores membranous E-cadherin via suppression of the epithelial-mesenchymal transition

inferred← citeshttps://doi.org/10.4172/2167-7700.1000126openalex-snapshot

Targeting the PI3K/AKT Pathway for the Treatment of Gastric Cancer

inferred← citeshttps://doi.org/10.4251/wjgo.v8.i9.673openalex-snapshot

Molecular mechanisms of chemoresistance in gastric cancer

inferred← citeshttps://doi.org/10.5230/jgc.2020.20.e12openalex-snapshot

LETM1 Promotes Gastric Cancer Cell Proliferation, Migration, and Invasion via the PI3K/Akt Signaling Pathway

inferred← citeshttps://doi.org/10.5567/pharmacologia.2013.414.427openalex-snapshot

Cellular Signals like MAPK/NF-kB/m-TOR Mediated Drug Resistance: A Promising Concept in Cancer Research

inferred← citeshttps://doi.org/10.5772/intechopen.69737openalex-snapshot

Molecular Prognostic Factors in Gastric Cancer

inferred← citeshttps://doi.org/10.61958/imhd1743openalex-snapshot

Pharmacological mechanism of salidroside in gastric cancer

inferred← citeshttps://doi.org/10.70675/940ea21dz0f9cz491ez968cz64a92ef468a5openalex-snapshot

Role of the calcium channel Orai3 in chemoresistance in lung cancer : involvement of cancer stem cells

inferred← citeshttps://doi.org/10.70675/d0db61dazb197z42dczbb98z6f0276f570b6openalex-snapshot

Rôle de la kinase Akt dans la chimiorésistance : Régulation de l’équilibre Apoptose-Sénescence

inferred← citeshttps://doi.org/10.7150/jca.27899openalex-snapshot

KRAS G12V Mutation is an Adverse Prognostic Factor of Chinese Gastric Cancer Patients

inferred← citeshttps://doi.org/10.7314/apjcp.2014.15.1.17openalex-snapshot

Roles of PTEN (Phosphatase and Tensin Homolog) in Gastric Cancer Development and Progression

inferred← citeshttps://doi.org/10.7314/apjcp.2015.16.11.4493openalex-snapshot

Are PIK3CA Mutation and Amplification Associated with Clinicopathological Characteristics of Gastric Cancer?

inferred← citeshttps://doi.org/10.7717/peerj.9400openalex-snapshot

Targeting secretory leukocyte protease inhibitor (SLPI) inhibits colorectal cancer cell growth, migration and invasion via downregulation of AKT

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.