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Peroxisome proliferator‐activated receptor gamma coactivator‐1α/HSF1 axis effectively alleviates lipopolysaccharide‐induced acute lung injury via suppressing oxidative stress and inflammatory response
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s12272-016-0857-yopenalex-snapshot
Astilbin alleviates sepsis-induced acute lung injury by inhibiting the expression of macrophage inhibitory factor in rats
inferredcites →https://doi.org/10.1016/j.ajpath.2011.03.013openalex-snapshot
Excessive Neutrophils and Neutrophil Extracellular Traps Contribute to Acute Lung Injury of Influenza Pneumonitis
inferredcites →https://doi.org/10.1016/j.cbi.2015.09.010openalex-snapshot
The protective effect of Trillin LPS-induced acute lung injury by the regulations of inflammation and oxidative state
inferredcites →https://doi.org/10.1016/j.cell.2006.09.024openalex-snapshot
Suppression of Reactive Oxygen Species and Neurodegeneration by the PGC-1 Transcriptional Coactivators
inferredcites →https://doi.org/10.1016/j.cmet.2015.08.005openalex-snapshot
Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis
inferredcites →https://doi.org/10.1016/j.intimp.2015.02.022openalex-snapshot
Hesperidin ameliorates lipopolysaccharide-induced acute lung injury in mice by inhibiting HMGB1 release
inferredcites →https://doi.org/10.1016/j.rbmo.2012.08.004openalex-snapshot
Roles of antioxidant enzymes in corpus luteum rescue from reactive oxygen species-induced oxidative stress
inferredcites →https://doi.org/10.1016/s0041-008x(03)00256-4openalex-snapshot
Use of Hsf1−/− mice reveals an essential role for HSF1 to protect lung against cadmium-induced injury
inferredcites →https://doi.org/10.1038/cddis.2016.22openalex-snapshot
The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1
inferredcites →https://doi.org/10.1038/nature07206openalex-snapshot
The role of exercise and PGC1α in inflammation and chronic disease
inferredcites →https://doi.org/10.1038/srep08347openalex-snapshot
Sirtinol Inhibits Neutrophil Elastase Activity and Attenuates Lipopolysaccharide-Mediated Acute Lung Injury in Mice
inferredcites →https://doi.org/10.1038/srep25298openalex-snapshot
Bufexamac ameliorates LPS-induced acute lung injury in mice by targeting LTA4H
inferredcites →https://doi.org/10.1038/srep31284openalex-snapshot
B7H3 ameliorates LPS-induced acute lung injury via attenuation of neutrophil migration and infiltration
inferredcites →https://doi.org/10.1074/jbc.m505890200openalex-snapshot
HSF1 Down-regulates XAF1 through Transcriptional Regulation
inferredcites →https://doi.org/10.1089/ars.2012.5149openalex-snapshot
Reactive Oxygen Species in Inflammation and Tissue Injury
inferredcites →https://doi.org/10.1155/2016/3630485openalex-snapshot
Matrine Attenuates COX-2 and ICAM-1 Expressions in Human Lung Epithelial Cells and Prevents Acute Lung Injury in LPS-Induced Mice
inferredcites →https://doi.org/10.1189/jlb.0212060openalex-snapshot
Severe multiple organ injury in HSF1 knockout mice induced by lipopolysaccharide is associated with an increase in neutrophil infiltration and surface expression of adhesion molecules
inferredcites →https://doi.org/10.1371/journal.pone.0010025openalex-snapshot
PGC-1alpha Down-Regulation Affects the Antioxidant Response in Friedreich's Ataxia
inferredcites →https://doi.org/10.1371/journal.ppat.1005954openalex-snapshot
SIRT1-PGC1α-NFκB Pathway of Oxidative and Inflammatory Stress during Trypanosoma cruzi Infection: Benefits of SIRT1-Targeted Therapy in Improving Heart Function in Chagas Disease
inferredcites →https://doi.org/10.2119/molmed.2010.00138openalex-snapshot
Contribution of Neutrophils to Acute Lung Injury
inferredcites →https://doi.org/10.3389/fimmu.2011.00065openalex-snapshot
Acute Lung Injury: How Macrophages Orchestrate Resolution of Inflammation and Tissue Repair
inferredcites →https://doi.org/10.3892/etm.2016.3465openalex-snapshot
Activation of AMPK attenuates LPS-induced acute lung injury by upregulation of PGC1α and SOD1
inferredcites →https://doi.org/10.3892/etm.2017.4353openalex-snapshot
Saturated hydrogen saline ameliorates lipopolysaccharide-induced acute lung injury by reducing excessive autophagy (Review)
inferredcites →https://doi.org/10.3892/ijmm.2016.2669openalex-snapshot
Picrasma quassiodes (D. Don) Benn. attenuates lipopolysaccharide (LPS)-induced acute lung injury
inferredcites →https://doi.org/10.3892/ol.2017.5972openalex-snapshot
Expression of PGC1α in glioblastoma multiforme patients
inferredcites →https://doi.org/10.4049/jimmunol.1300959openalex-snapshot
Akt2 Deficiency Protects from Acute Lung Injury via Alternative Macrophage Activation and miR-146a Induction in Mice
inferredcites →https://doi.org/10.7499/j.issn.1008-8830.2017.02.018openalex-snapshot
[Effect of heat shock factor 1 on airway hyperresponsiveness and airway inflammation in mice with allergic asthma].
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4794612openalex-extracted
Molecular Mechanism of 4-Hydroxynonenal Induced Cell Death
inferred← citeshttps://doi.org/10.1007/s00018-024-05242-yopenalex-snapshot
LPS-induced monocarboxylate transporter-1 inhibition facilitates lactate accumulation triggering epithelial-mesenchymal transformation and pulmonary fibrosis
inferred← citeshttps://doi.org/10.1007/s00395-022-00910-1openalex-snapshot
Mechanism of the switch from NO to H2O2 in endothelium-dependent vasodilation in diabetes
inferred← citeshttps://doi.org/10.1007/s12192-022-01314-9openalex-snapshot
Nutri-stress, mitochondrial dysfunction, and insulin resistance—role of heat shock proteins
inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00238-2openalex-snapshot
Inflammatory Cells of the Lung: Macrophages
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110978openalex-snapshot
Tamoxifen induced cardiac damage via the IL-6/p-STAT3/PGC-1α pathway
inferred← citeshttps://doi.org/10.1016/j.jid.2021.11.007openalex-snapshot
HSF1-Dependent Autophagy Activation Contributes to the Survival of Melanocytes Under Oxidative Stress in Vitiligo
inferred← citeshttps://doi.org/10.1016/j.lfs.2019.117120openalex-snapshot
HMGB1 was negatively regulated by HSF1 and mediated the TLR4/MyD88/NF-κB signal pathway in asthma
inferred← citeshttps://doi.org/10.1016/j.molimm.2023.10.001openalex-snapshot
The role of the Gas6/TAM signal pathway in the LPS-induced pulmonary epithelial cells injury
inferred← citeshttps://doi.org/10.1016/j.redox.2026.104308openalex-snapshot
The CYP1A-HSF1 axis alleviates mitochondrial oxidative stress to limit HBO-induced lung endothelial barrier damage
inferred← citeshttps://doi.org/10.1021/acs.jafc.4c09302openalex-snapshot
HSF1 Mediates Palmitic Acid-Disrupted Lipid Metabolism and Inflammatory Response by Maintaining Endoplasmic Reticulum Homeostasis in Fish
inferred← citeshttps://doi.org/10.1080/21655979.2022.2033381openalex-snapshot
Crosstalk of pyroptosis, ferroptosis, and mitochondrial aldehyde dehydrogenase 2-related mechanisms in sepsis-induced lung injury in a mouse model
inferred← citeshttps://doi.org/10.1097/imna-d-22-00018openalex-snapshot
Treatment of COVID-19-Induced Systematic Inflammatory Response and Multiple Organ Failure Using Xuebijing
inferred← citeshttps://doi.org/10.1186/s11658-020-00205-0openalex-snapshot
Ferrostatin-1 alleviates lipopolysaccharide-induced acute lung injury via inhibiting ferroptosis
inferred← citeshttps://doi.org/10.1186/s12890-024-03145-zopenalex-snapshot
Predictive value of serum MED1 and PGC-1α for bronchopulmonary dysplasia in preterm infants
inferred← citeshttps://doi.org/10.1186/s12931-025-03422-3openalex-snapshot
Lipopolysaccharide-induced histone lactylation mediates m6A RNA modification causing mitochondrial dysfunction and pulmonary fibroblasts activation to exacerbate sepsis-associated pulmonary fibrosis
inferred← citeshttps://doi.org/10.1186/s12931-025-03468-3openalex-snapshot
Mitochondrial quality control mechanisms as molecular targets for impaired lung development: from fetuses to neonates
inferred← citeshttps://doi.org/10.1186/s40360-024-00787-xopenalex-snapshot
Sodium Houttuyniae attenuates ferroptosis by regulating TRAF6-c-Myc signaling pathways in lipopolysaccharide-induced acute lung injury (ALI)
inferred← citeshttps://doi.org/10.1515/biol-2020-0015openalex-snapshot
Protective effect of asiaticoside on radiation-induced proliferation inhibition and DNA damage of fibroblasts and mice death
inferred← citeshttps://doi.org/10.3389/fimmu.2022.781003openalex-snapshot
HSF1 Protects Sepsis-Induced Acute Lung Injury by Inhibiting NLRP3 Inflammasome Activation
inferred← citeshttps://doi.org/10.3390/biom12081094openalex-snapshot
Can PPAR γ Keep Cadmium in Check?
inferred← citeshttps://doi.org/10.3390/molecules23123322openalex-snapshot
Cardioprotective Effects of Puerarin-V on Isoproterenol-Induced Myocardial Infarction Mice Is Associated with Regulation of PPAR-Υ/NF-κB Pathway
inferred← citeshttps://doi.org/10.3892/ijmm.2023.5309openalex-snapshot
The role of heat shock proteins in the pathogenesis of heart failure (Review)
inferred← citeshttps://doi.org/10.6084/m9.figshare.26962408openalex-snapshot
Additional file 1 of Sodium Houttuyniae attenuates ferroptosis by regulating TRAF6-c-Myc signaling pathways in lipopolysaccharide-induced acute lung injury (ALI)
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