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Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ijc.10608openalex-snapshotCopper‐transporting P‐type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: Comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP
inferredcites →https://doi.org/10.1002/ijc.27320openalex-snapshotPhotodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: A phase II study
inferredcites →https://doi.org/10.1002/jcb.24896openalex-snapshotProgeny From Irradiated Colorectal Cancer Cells Acquire an EMT‐Like Phenotype and Activate Wnt/β‐Catenin Pathway
inferredcites →https://doi.org/10.1002/mco2.55openalex-snapshotMolecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment
inferredcites →https://doi.org/10.1002/pros.23435openalex-snapshotPredictive value of epithelial‐mesenchymal‐transition (EMT) signature and PARP‐1 in prostate cancer radioresistance
inferredcites →https://doi.org/10.1007/s13277-015-3636-3openalex-snapshotResveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity
inferredcites →https://doi.org/10.1016/s0021-9258(18)99069-1openalex-snapshotCharacterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication
inferredcites →https://doi.org/10.1016/s1368-8375(02)00038-6openalex-snapshotExpression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin
inferredcites →https://doi.org/10.1038/35060032openalex-snapshotCytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
inferredcites →https://doi.org/10.1038/bjc.1993.322openalex-snapshotIn vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin
inferredcites →https://doi.org/10.1038/cddis.2014.415openalex-snapshotPI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways
inferredcites →https://doi.org/10.1038/sj.bjc.6606071openalex-snapshotRole of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1038/sj.cdd.4401248openalex-snapshotLoss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line
inferredcites →https://doi.org/10.1038/sj.onc.1203668openalex-snapshotSpontaneous development of drug resistance: mismatch repair and p53 defects in resistance to cisplatin in human tumor cells
inferredcites →https://doi.org/10.1038/srep21010openalex-snapshotβ-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1
inferredcites →https://doi.org/10.1038/srep30689openalex-snapshotCell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo
inferredcites →https://doi.org/10.1046/j.1523-1747.2003.12313.xopenalex-snapshotOverexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to Cisplatin
inferredcites →https://doi.org/10.1054/bjoc.2000.1295openalex-snapshotA phase II study of paclitaxel, weekly, 24-hour continuous infusion 5-fluorouracil, folinic acid and cisplatin in patients with advanced gastric cancer
inferredcites →https://doi.org/10.1093/annonc/mdh264openalex-snapshot5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
inferredcites →https://doi.org/10.1101/gad.1897010openalex-snapshotChronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
inferredcites →https://doi.org/10.1111/bph.13836openalex-snapshotDual cyclin‐dependent kinase 4/6 inhibition by PD‐0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells
inferredcites →https://doi.org/10.1111/cas.12328openalex-snapshotN 1‐guanyl‐1,7‐diaminoheptane sensitizes bladder cancer cells to doxorubicin by preventing epithelial–mesenchymal transition through inhibition of eukaryotic translation initiation factor 5 A 2 activation
inferredcites →https://doi.org/10.1111/jop.12423openalex-snapshotThe relationship between EMT, CD44high/EGFRlow phenotype, and treatment response in head and neck cancer cell lines
inferredcites →https://doi.org/10.1128/mcb.18.6.3245openalex-snapshotRACK1, a Receptor for Activated C Kinase and a Homolog of the β Subunit of G Proteins, Inhibits Activity of Src Tyrosine Kinases and Growth of NIH 3T3 Cells
inferredcites →https://doi.org/10.1139/o10-150openalex-snapshotMechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-1196openalex-snapshotCompetitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance
inferredcites →https://doi.org/10.1159/000044993openalex-snapshotTranscription of the XRCC1 Gene in Kidneys of Radiosensitive and Radioresistant Mice following Whole-Body Irradiation
inferredcites →https://doi.org/10.1177/1758834014539183openalex-snapshotAdo-trastuzumab emtansine (T-DM1) in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer: latest evidence and clinical potential
inferredcites →https://doi.org/10.1186/1476-4598-12-94openalex-snapshotNon-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
inferredcites →https://doi.org/10.1186/1748-717x-8-241openalex-snapshotThree-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: clinical efficacy and failure pattern
inferredcites →https://doi.org/10.1186/1748-717x-8-31openalex-snapshotXRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients
inferredcites →https://doi.org/10.1186/s12967-015-0464-6openalex-snapshotFH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R
inferredcites →https://doi.org/10.1186/s13014-015-0534-1openalex-snapshotRETRACTED ARTICLE: IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation
inferredcites →https://doi.org/10.1200/jco.2004.08.009openalex-snapshotFour Decades of Continuing Innovation With Fluorouracil: Current and Future Approaches to Fluorouracil Chemoradiation Therapy
inferredcites →https://doi.org/10.1371/journal.pone.0126149openalex-snapshotFractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation
inferredcites →https://doi.org/10.14989/doctor.k19597openalex-snapshotNovel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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inferred← citeshttps://doi.org/10.1002/jcb.30488openalex-snapshotThe role of p62 in cell death and survival of 5‐fluorouracil and oxaliplatin‐resistant colorectal cancer cells
inferred← citeshttps://doi.org/10.1002/mma.70085openalex-snapshotMathematical Modeling and Optimal Control of Combined Virotherapy and Adoptive T Cell Therapy for Cancer Treatment
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inferred← citeshttps://doi.org/10.1002/wnan.1876openalex-snapshotInnovative nanotheranostics: Smart nanoparticles based approach to overcome breast cancer stem cells mediated chemo‐ and radioresistances
inferred← citeshttps://doi.org/10.1007/s10238-024-01527-5openalex-snapshotAutophagy-based therapy for hepatocellular carcinoma: from standard treatments to combination therapy, oncolytic virotherapy, and targeted nanomedicines
inferred← citeshttps://doi.org/10.1007/s10388-024-01097-1openalex-snapshotOptimizing neoadjuvant radiotherapy for locally advanced esophageal squamous cell carcinoma: a comprehensive review on the role of concomitant or sequential immune checkpoint inhibitors
inferred← citeshttps://doi.org/10.1007/s10895-023-03145-yopenalex-snapshotThe Determination of Cisplatin and Luteolin Synergistic Effect on Colorectal Cancer Cell Apoptosis and Mitochondrial Dysfunction by Fluorescence Labelling
inferred← citeshttps://doi.org/10.1007/s12032-023-01948-4openalex-snapshotRevamping the innate or innate-like immune cell-based therapy for hepatocellular carcinoma: new mechanistic insights and advanced opportunities
inferred← citeshttps://doi.org/10.1007/s12032-024-02586-0openalex-snapshotGRP78 as a potential therapeutic target in cancer treatment: an updated review of its role in chemoradiotherapy resistance of cancer cells
inferred← citeshttps://doi.org/10.1007/s12032-026-03251-4openalex-snapshotNatural simple coumarins and their interaction with AKR1C3: implications for overcoming chemoradioresistance in gastrointestinal carcinomas
inferred← citeshttps://doi.org/10.1007/s12602-026-11189-2openalex-snapshotGut Limosilactobacillus reuteri-secreted Components Mitigate Susceptibility to Radiation by Alleviating Oxidative Stress in the Intestinal Epithelium
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