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Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment

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Medical Treatment of Advanced Testicular Cancer
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p53 sequence analysis predicts treatment response and outcome of patients with esophageal carcinoma
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Metallothionein expression in ovarian cancer in relation to histopathological parameters and molecular markers of prognosis
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The PARP superfamily
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Activation of PTGS2/NF‐κB signaling pathway enhances radiation resistance of glioma
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Trastuzumab‐associated cardiotoxicity
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Endogenous association of Bim BH3‐only protein with Mcl‐1, Bcl‐xL and Bcl‐2 on mitochondria in human B cells
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Targeting tumor cells by enhancing radiation sensitivity
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Copper‐transporting P‐type adenosine triphosphatase (ATP7B) as a cisplatin based chemoresistance marker in ovarian carcinoma: Comparative analysis with expression of MDR1, MRP1, MRP2, LRP and BCRP
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Photodynamic therapy as salvage treatment for local failure after chemoradiotherapy in patients with esophageal squamous cell carcinoma: A phase II study
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STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo
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Appearance and detection of multiple copies of the mdr‐1 gene in clinical samples of mammary carcinoma
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Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells
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Progeny From Irradiated Colorectal Cancer Cells Acquire an EMT‐Like Phenotype and Activate Wnt/β‐Catenin Pathway
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Molecular mechanisms of chemo‐ and radiotherapy resistance and the potential implications for cancer treatment
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Predictive value of epithelial‐mesenchymal‐transition (EMT) signature and PARP‐1 in prostate cancer radioresistance
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Mechanisms of Multidrug Resistance in Cancer
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The epidermal growth factor receptor family: Biology driving targeted therapeutics
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Cyclin D1, cancer progression, and opportunities in cancer treatment
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Nuclear metallothionein expression correlates with cisplatin resistance of ovarian cancer cells and poor clinical outcome
inferredcites →https://doi.org/10.1007/s00432-018-2774-6openalex-snapshot
PARP inhibitors affect growth, survival and radiation susceptibility of human alveolar and embryonal rhabdomyosarcoma cell lines
inferredcites →https://doi.org/10.1007/s11010-016-2816-9openalex-snapshot
Involvement of microRNA-141-3p in 5-fluorouracil and oxaliplatin chemo-resistance in esophageal cancer cells via regulation of PTEN
inferredcites →https://doi.org/10.1007/s11060-010-0195-8openalex-snapshot
STAT3 tyrosine phosphorylation influences survival in glioblastoma
inferredcites →https://doi.org/10.1007/s11596-014-1349-2openalex-snapshot
Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells
inferredcites →https://doi.org/10.1007/s11605-015-3000-3openalex-snapshot
Minnelide Overcomes Oxaliplatin Resistance by Downregulating the DNA Repair Pathway in Pancreatic Cancer
inferredcites →https://doi.org/10.1007/s11626-014-9779-5openalex-snapshot
Curcumin suppresses proliferation and invasion in non-small cell lung cancer by modulation of MTA1-mediated Wnt/β-catenin pathway
inferredcites →https://doi.org/10.1007/s12013-014-9995-3openalex-snapshot
Enhanced Radiosensitivity and G2/M Arrest were Observed in Radioresistant Esophageal Cancer Cells by Knocking Down RPA Expression
inferredcites →https://doi.org/10.1007/s12325-009-0048-zopenalex-snapshot
Cardiotoxicity associated with trastuzumab treatment of HER2+ breast cancer
inferredcites →https://doi.org/10.1007/s13277-015-3264-yopenalex-snapshot
DYRK2 regulates epithelial-mesenchymal-transition and chemosensitivity through Snail degradation in ovarian serous adenocarcinoma
inferredcites →https://doi.org/10.1007/s13277-015-3636-3openalex-snapshot
Resveratrol induces AMPK-dependent MDR1 inhibition in colorectal cancer HCT116/L-OHP cells by preventing activation of NF-κB signaling and suppressing cAMP-responsive element transcriptional activity
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Palbociclib: First Global Approval
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Metallothionein content correlates with the sensitivity of human small cell lung cancer cell lines to cisplatin
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Multidrug resistance: Physiological principles and nanomedical solutions
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MDR1 mediated chemoresistance: BMI1 and TIP60 in action
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Cisplatin resistance: Preclinical findings and clinical implications
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Bmi-1 confers adaptive radioresistance to KYSE-150R esophageal carcinoma cells
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Inhibition of STAT3/cyclinD1 pathway promotes chemotherapeutic sensitivity of colorectal caner
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Targeting inflammatory pathways for tumor radiosensitization
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The centrosome and the DNA damage induced checkpoint
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Ionizing radiation-induced metabolic oxidative stress and prolonged cell injury
inferredcites →https://doi.org/10.1016/j.canlet.2014.09.020openalex-snapshot
Induction of autophagy counteracts the anticancer effect of cisplatin in human esophageal cancer cells with acquired drug resistance
inferredcites →https://doi.org/10.1016/j.canlet.2016.11.008openalex-snapshot
EAI045: The fourth-generation EGFR inhibitor overcoming T790M and C797S resistance
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Entinostat reverses cisplatin resistance in esophageal squamous cell carcinoma via down-regulation of multidrug resistance gene 1
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Enhancing Tumor-Specific Uptake of the Anticancer Drug Cisplatin with a Copper Chelator
inferredcites →https://doi.org/10.1016/j.cellsig.2007.03.001openalex-snapshot
Protein trafficking in response to DNA damage
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DNA repair gets physical: Mapping an XPA-binding site on ERCC1
inferredcites →https://doi.org/10.1016/j.dnarep.2010.03.010openalex-snapshot
Downregulation of XPF–ERCC1 enhances cisplatin efficacy in cancer cells☆
inferredcites →https://doi.org/10.1016/j.ejca.2012.12.013openalex-snapshot
The upregulation of dihydropyrimidine dehydrogenase in liver is involved in acquired resistance to 5-fluorouracil
inferredcites →https://doi.org/10.1016/j.etap.2013.04.009openalex-snapshot
XRCC1 deficiency increased the DNA damage induced by γ-ray in HepG2 cell: Involvement of DSB repair and cell cycle arrest
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Decreased DNA repair gene XRCC1 expression is associated with radiotherapy-induced acute side effects in breast cancer patients
inferredcites →https://doi.org/10.1016/j.gie.2012.05.013openalex-snapshot
Molecular in vivo imaging of gastric cancer in a human-murine xenograft model: targeting epidermal growth factor receptor
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Cetuximab With Concurrent Chemoradiation for Esophagogastric Cancer: Assessment of Toxicity
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Curcumin Modulates the Radiosensitivity of Colorectal Cancer Cells by Suppressing Constitutive and Inducible NF-κB Activity
inferredcites →https://doi.org/10.1016/j.ijrobp.2018.03.039openalex-snapshot
Evaluation of XRCC1 Gene Polymorphism as a Biomarker in Head and Neck Cancer Patients Undergoing Chemoradiation Therapy
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The role of copper transporters in the development of resistance to Pt drugs
inferredcites →https://doi.org/10.1016/j.jinorgbio.2008.11.012openalex-snapshot
Effects of the loss of Atox1 on the cellular pharmacology of cisplatin
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Copper transporter CTR1 expression and tissue platinum concentration in non-small cell lung cancer
inferredcites →https://doi.org/10.1016/j.molonc.2014.08.003openalex-snapshot
Abrogation of radioresistance in glioblastoma stem‐like cells by inhibition of ATM kinase
inferredcites →https://doi.org/10.1016/j.mrfmmm.2012.01.005openalex-snapshot
PARP-1 inhibition induces a late increase in the level of reactive oxygen species in cells after ionizing radiation
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FoxM1 Induced Paclitaxel Resistance via Activation of the FoxM1/PHB1/RAF-MEK-ERK Pathway and Enhancement of the ABCA2 Transporter
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Association between single nucleotide polymorphisms in the gene for XRCC1 and radiation-induced late toxicity in prostate cancer patients
inferredcites →https://doi.org/10.1016/j.radonc.2011.06.002openalex-snapshot
Autophagy contributes to resistance of tumor cells to ionizing radiation
inferredcites →https://doi.org/10.1016/j.radonc.2013.10.040openalex-snapshot
CD133+ cells contribute to radioresistance via altered regulation of DNA repair genes in human lung cancer cells
inferredcites →https://doi.org/10.1016/j.radonc.2015.08.012openalex-snapshot
AMPK-independent autophagy promotes radioresistance of human tumor cells under clinical relevant hypoxia in vitro
inferredcites →https://doi.org/10.1016/j.stemcr.2017.03.026openalex-snapshot
Resistance to Taxanes in Triple-Negative Breast Cancer Associates with the Dynamics of a CD49f+ Tumor-Initiating Population
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Hitting cancers’ weak spots: vulnerabilities imposed by p53 mutation
inferredcites →https://doi.org/10.1016/j.yexcr.2018.08.025openalex-snapshot
RPA1 downregulation enhances nasopharyngeal cancer radiosensitivity via blocking RAD51 to the DNA damage site
inferredcites →https://doi.org/10.1016/j.ygyno.2004.12.042openalex-snapshot
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a prognostic factor in human endometrial carcinoma
inferredcites →https://doi.org/10.1016/j.ygyno.2006.10.061openalex-snapshot
Weakened spindle checkpoint with reduced BubR1 expression in paclitaxel-resistant ovarian carcinoma cell line SKOV3-TR30
inferredcites →https://doi.org/10.1016/j.ygyno.2018.07.002openalex-snapshot
Radiosensitization by the PARP inhibitor olaparib in BRCA1-proficient and deficient high-grade serous ovarian carcinomas
inferredcites →https://doi.org/10.1016/s0021-9258(18)99069-1openalex-snapshot
Characterization of a cDNA encoding the 70-kDa single-stranded DNA-binding subunit of human replication protein A and the role of the protein in DNA replication
inferredcites →https://doi.org/10.1016/s0024-3205(97)00958-2openalex-snapshot
The transcription of the XRCC1 gene in spleen following ionizing irradiation in radiosensitive and radioresistant mice
inferredcites →https://doi.org/10.1016/s0306-3623(98)00191-8openalex-snapshot
Resistance to 5-Fluorouracil
inferredcites →https://doi.org/10.1016/s0360-3016(01)01489-4openalex-snapshot
ATM protein expression correlates with radioresistance in primary glioblastoma cells in culture
inferredcites →https://doi.org/10.1016/s0925-4439(02)00082-0openalex-snapshot
Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism
inferredcites →https://doi.org/10.1016/s0952-7915(96)80132-4openalex-snapshot
Phosphatidylinositol 3-kinase related kinases
inferredcites →https://doi.org/10.1016/s0959-8049(99)00211-7openalex-snapshot
Can dihydropyrimidine dehydrogenase impact 5-fluorouracil-based treatment?
inferredcites →https://doi.org/10.1016/s1368-8375(02)00038-6openalex-snapshot
Expression of copper-transporting P-type adenosine triphosphatase (ATP7B) as a chemoresistance marker in human oral squamous cell carcinoma treated with cisplatin
inferredcites →https://doi.org/10.1016/s1383-5742(00)00023-5openalex-snapshot
Alterations of oncogenes and tumor suppressor genes in esophageal cancer in China
inferredcites →https://doi.org/10.1017/s1462399408000744openalex-snapshot
p21 and p27: roles in carcinogenesis and drug resistance
inferredcites →https://doi.org/10.1021/acs.chemrev.5b00597openalex-snapshot
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
inferredcites →https://doi.org/10.1021/acs.jmedchem.8b00185openalex-snapshot
Dual-Specificity Tyrosine Phosphorylation-Regulated Kinase 1A (DYRK1A) Inhibitors as Potential Therapeutics
inferredcites →https://doi.org/10.1021/jm500766wopenalex-snapshot
Ado-trastuzumab Emtansine (T-DM1): An Antibody–Drug Conjugate (ADC) for HER2-Positive Breast Cancer
inferredcites →https://doi.org/10.1038/35060032openalex-snapshot
Cytoplasmic localization of p21Cip1/WAF1 by Akt-induced phosphorylation in HER-2/neu-overexpressing cells
inferredcites →https://doi.org/10.1038/bjc.1993.322openalex-snapshot
In vitro platinum drug chemosensitivity of human cervical squamous cell carcinoma cell lines with intrinsic and acquired resistance to cisplatin
inferredcites →https://doi.org/10.1038/cddis.2014.415openalex-snapshot
PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways
inferredcites →https://doi.org/10.1038/nature05236openalex-snapshot
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
inferredcites →https://doi.org/10.1038/nature08467openalex-snapshot
The DNA-damage response in human biology and disease
inferredcites →https://doi.org/10.1038/ncb1208openalex-snapshot
The human mitotic checkpoint protein BubR1 regulates chromosome–spindle attachments
inferredcites →https://doi.org/10.1038/nrc2167openalex-snapshot
The resurgence of platinum-based cancer chemotherapy
inferredcites →https://doi.org/10.1038/nrc2342openalex-snapshot
DNA repair pathways as targets for cancer therapy
inferredcites →https://doi.org/10.1038/nrm1962openalex-snapshot
EGF–ERBB signalling: towards the systems level
inferredcites →https://doi.org/10.1038/nrm1963openalex-snapshot
Poly(ADP-ribose): novel functions for an old molecule
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Molecular mechanisms of epithelial–mesenchymal transition
inferredcites →https://doi.org/10.1038/onc.2011.384openalex-snapshot
Molecular mechanisms of cisplatin resistance
inferredcites →https://doi.org/10.1038/oncsis.2012.12openalex-snapshot
Activation of the AKT/cyclin D1/Cdk4 survival signaling pathway in radioresistant cancer stem cells
inferredcites →https://doi.org/10.1038/s41392-020-0150-xopenalex-snapshot
DNA damage response signaling pathways and targets for radiotherapy sensitization in cancer
inferredcites →https://doi.org/10.1038/s41420-020-00322-xopenalex-snapshot
EDIL3 promotes epithelial–mesenchymal transition and paclitaxel resistance through its interaction with integrin αVβ3 in cancer cells
inferredcites →https://doi.org/10.1038/s41598-017-04301-8openalex-snapshot
Synergistic effects of various Her inhibitors in combination with IGF-1R, C-MET and Src targeting agents in breast cancer cell lines
inferredcites →https://doi.org/10.1038/sj.bjc.6606071openalex-snapshot
Role of multidrug resistance protein 2 (MRP2) in chemoresistance and clinical outcome in oesophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1038/sj.cdd.4401248openalex-snapshot
Loss of drug-induced activation of the CD95 apoptotic pathway in a cisplatin-resistant testicular germ cell tumor cell line
inferredcites →https://doi.org/10.1038/sj.emboj.7601894openalex-snapshot
Structural basis for the recruitment of ERCC1‐XPF to nucleotide excision repair complexes by XPA
inferredcites →https://doi.org/10.1038/sj.onc.1203668openalex-snapshot
Spontaneous development of drug resistance: mismatch repair and p53 defects in resistance to cisplatin in human tumor cells
inferredcites →https://doi.org/10.1038/srep21010openalex-snapshot
β-elemene sensitizes hepatocellular carcinoma cells to oxaliplatin by preventing oxaliplatin-induced degradation of copper transporter 1
inferredcites →https://doi.org/10.1038/srep30689openalex-snapshot
Cell-cycle-controlled radiation therapy was effective for treating a murine malignant melanoma cell line in vitro and in vivo
inferredcites →https://doi.org/10.1039/c3cc45905eopenalex-snapshot
Copper binding promotes the interaction of cisplatin with human copper chaperone Atox1
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Overexpression of cMOAT (MRP2/ABCC2) Is Associated with Decreased Formation of Platinum-DNA Adducts and Decreased G2-Arrest in Melanoma Cells Resistant to Cisplatin
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Glutathione S-transferase-π overexpression is closely associated with K-ras mutation during human colon carcinogenesis
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A phase II study of paclitaxel, weekly, 24-hour continuous infusion 5-fluorouracil, folinic acid and cisplatin in patients with advanced gastric cancer
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Molecular mechanisms of resistance to taxanes and therapeutic implications
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ERCC1 Isoform Expression and DNA Repair in Non–Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1056/nejmra035010openalex-snapshot
Esophageal Cancer
inferredcites →https://doi.org/10.1073/pnas.0606599104openalex-snapshot
WNT/β-catenin mediates radiation resistance of mouse mammary progenitor cells
inferredcites →https://doi.org/10.1074/jbc.m010346200openalex-snapshot
RACK1 Interacts with E1A and Rescues E1A-induced Yeast Growth Inhibition and Mammalian Cell Apoptosis
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Radiation-induced DNA damage response and resistance in colorectal cancer stem-like cells
inferredcites →https://doi.org/10.1091/mbc.01-09-0437openalex-snapshot
Checkpoint Protein BubR1 Acts Synergistically with Mad2 to Inhibit Anaphase-promoting Complex
inferredcites →https://doi.org/10.1093/annonc/mdh264openalex-snapshot
5-Fluorouracil incorporation into RNA and DNA in relation to thymidylate synthase inhibition of human colorectal cancers
inferredcites →https://doi.org/10.1093/annonc/mdm172openalex-snapshot
Mechanisms of multidrug resistance: the potential role of microtubule-stabilizing agents
inferredcites →https://doi.org/10.1093/annonc/mdw129openalex-snapshot
Osimertinib (AZD9291)—a science-driven, collaborative approach to rapid drug design and development
inferredcites →https://doi.org/10.1093/carcin/23.5.687openalex-snapshot
Sensing and repairing DNA double-strand breaks
inferredcites →https://doi.org/10.1097/cad.0000000000000057openalex-snapshot
Taxanes
inferredcites →https://doi.org/10.1097/md.0000000000004766openalex-snapshot
Cancer stem cells
inferredcites →https://doi.org/10.1097/md.0000000000008202openalex-snapshot
Association between XRCC1 single-nucleotide polymorphism and acute radiation reaction in patients with nasopharyngeal carcinoma
inferredcites →https://doi.org/10.1101/cshperspect.a012716openalex-snapshot
DNA Damage Sensing by the ATM and ATR Kinases
inferredcites →https://doi.org/10.1101/gad.1897010openalex-snapshot
Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer
inferredcites →https://doi.org/10.1111/1750-3841.15156openalex-snapshot
Allicin enhances the radiosensitivity of colorectal cancer cells via inhibition of NF‐κB signaling pathway
inferredcites →https://doi.org/10.1111/bph.13836openalex-snapshot
Dual cyclin‐dependent kinase 4/6 inhibition by PD‐0332991 induces apoptosis and senescence in oesophageal squamous cell carcinoma cells
inferredcites →https://doi.org/10.1111/cas.12328openalex-snapshot
N 1‐guanyl‐1,7‐diaminoheptane sensitizes bladder cancer cells to doxorubicin by preventing epithelial–mesenchymal transition through inhibition of eukaryotic translation initiation factor 5 A 2 activation
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Identification of candidate genes involved in the radiosensitivity of esophageal cancer cells by microarray analysis
inferredcites →https://doi.org/10.1111/j.1442-2050.2008.00820.xopenalex-snapshot
Predictors of response and survival for neoadjuvant treated patients with esophageal adenocarcinoma
inferredcites →https://doi.org/10.1111/j.1442-2050.2010.01138.xopenalex-snapshot
The radiosensitization effect of NS398 on esophageal cancer stem cell-like radioresistant cells
inferredcites →https://doi.org/10.1111/j.1742-4658.2011.08235.xopenalex-snapshot
Multidrug resistance proteins (MRPs/ABCCs) in cancer chemotherapy and genetic diseases
inferredcites →https://doi.org/10.1111/jop.12423openalex-snapshot
The relationship between EMT, CD44high/EGFRlow phenotype, and treatment response in head and neck cancer cell lines
inferredcites →https://doi.org/10.1126/science.1346476openalex-snapshot
Modulation of Activity of the Promoter of the Human MDR 1 Gene by Ras and p53
inferredcites →https://doi.org/10.1126/science.2470152openalex-snapshot
Studies of the HER-2/ neu Proto-Oncogene in Human Breast and Ovarian Cancer
inferredcites →https://doi.org/10.1128/mcb.00293-08openalex-snapshot
ERCC1-XPF Endonuclease Facilitates DNA Double-Strand Break Repair
inferredcites →https://doi.org/10.1128/mcb.18.6.3245openalex-snapshot
RACK1, a Receptor for Activated C Kinase and a Homolog of the β Subunit of G Proteins, Inhibits Activity of Src Tyrosine Kinases and Growth of NIH 3T3 Cells
inferredcites →https://doi.org/10.1139/o10-150openalex-snapshot
Mechanism of tumor resistance to cisplatin mediated by the copper transporter ATP7BThis paper is one of a selection of papers published in a Special Issue entitled CSBMCB 53rd Annual Meeting — Membrane Proteins in Health and Disease, and has undergone the Journal’s usual peer review process.
inferredcites →https://doi.org/10.1142/10407openalex-snapshot
Cancer Cell Chemoresistance and Chemosensitization
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REPLICATION PROTEIN A: A Heterotrimeric, Single-Stranded DNA-Binding Protein Required for Eukaryotic DNA Metabolism
inferredcites →https://doi.org/10.1155/2011/978312openalex-snapshot
Recent Advances in p53 Research and Cancer Treatment
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Stemness in Cancer: Stem Cells, Cancer Stem Cells, and Their Microenvironment
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The Forkhead Box m1 Transcription Factor Stimulates the Proliferation of Tumor Cells during Development of Lung Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-11-0640openalex-snapshot
FoxM1: A Master Regulator of Tumor Metastasis
inferredcites →https://doi.org/10.1158/0008-5472.can-12-3537openalex-snapshot
NF-κB Regulates Radioresistance Mediated By β1-Integrin in Three-Dimensional Culture of Breast Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-12-3859openalex-snapshot
Dysregulated Expression of FOXM1 Isoforms Drives Progression of Pancreatic Cancer
inferredcites →https://doi.org/10.1158/0008-5472.can-14-0306openalex-snapshot
RPA Inhibition Increases Replication Stress and Suppresses Tumor Growth
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-0137openalex-snapshot
Increased Expression of the Copper Efflux Transporter ATP7A Mediates Resistance to Cisplatin, Carboplatin, and Oxaliplatin in Ovarian Cancer Cells
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-1387openalex-snapshot
High Gene Expression of TS1, GSTP1, and ERCC1 Are Risk Factors for Survival in Patients Treated with Trimodality Therapy for Esophageal Cancer
inferredcites →https://doi.org/10.1158/1078-0432.ccr-07-1528openalex-snapshot
Treatment of Radioresistant Stem-Like Esophageal Cancer Cells by an Apoptotic Gene-Armed, Telomerase-Specific Oncolytic Adenovirus
inferredcites →https://doi.org/10.1158/1078-0432.ccr-10-1604openalex-snapshot
High XRCC1 Protein Expression Is Associated with Poorer Survival in Patients with Head and Neck Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-0244openalex-snapshot
Early G1 Cyclin-Dependent Kinases as Prognostic Markers and Potential Therapeutic Targets in Esophageal Adenocarcinoma
inferredcites →https://doi.org/10.1158/1078-0432.ccr-11-1214openalex-snapshot
Expression of FoxM1 Is Required for the Proliferation of Medulloblastoma Cells and Indicates Worse Survival of Patients
inferredcites →https://doi.org/10.1158/1078-0432.ccr-15-1196openalex-snapshot
Competitive Binding Between Id1 and E2F1 to Cdc20 Regulates E2F1 Degradation and Thymidylate Synthase Expression to Promote Esophageal Cancer Chemoresistance
inferredcites →https://doi.org/10.1158/1078-0432.ccr-18-0401openalex-snapshot
Talazoparib Is a Potent Radiosensitizer in Small Cell Lung Cancer Cell Lines and Xenografts
inferredcites →https://doi.org/10.1158/1535-7163.985.3.8openalex-snapshot
Inhibition of constitutively activated nuclear factor-κB radiosensitizes human melanoma cells
inferredcites →https://doi.org/10.1158/1535-7163.mct-13-0791openalex-snapshot
Targeting Microtubules by Natural Agents for Cancer Therapy
inferredcites →https://doi.org/10.1158/1535-7163.mct-14-0636openalex-snapshot
Tumor-Related Molecular Mechanisms of Oxaliplatin Resistance
inferredcites →https://doi.org/10.1159/000044993openalex-snapshot
Transcription of the XRCC1 Gene in Kidneys of Radiosensitive and Radioresistant Mice following Whole-Body Irradiation
inferredcites →https://doi.org/10.1159/000484167openalex-snapshot
Mechanisms of Resistance to CDK4/6 Inhibitors in Breast Cancer and Potential Biomarkers of Response
inferredcites →https://doi.org/10.1172/jci12415openalex-snapshot
Modulation of MDR/MRP by wild-type and mutant p53
inferredcites →https://doi.org/10.1172/jci134930openalex-snapshot
Ribosomal S6 protein kinase 4 promotes radioresistance in esophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1177/172460080602100203openalex-snapshot
p53 and HER2/neu Expression in Relation to Chemotherapy Response in Patients with Non-Small Cell Lung Cancer
inferredcites →https://doi.org/10.1177/1758834014539183openalex-snapshot
Ado-trastuzumab emtansine (T-DM1) in human epidermal growth factor receptor 2 (HER2)-positive metastatic breast cancer: latest evidence and clinical potential
inferredcites →https://doi.org/10.1177/1947601911411084openalex-snapshot
Ras in Cancer and Developmental Diseases
inferredcites →https://doi.org/10.11817/j.issn.1672-7347.2018.12.015openalex-snapshot
[Research progress of copper transporter 1 in platinum-based chemotherapy].
inferredcites →https://doi.org/10.1186/1471-2407-14-706openalex-snapshot
Lymph node enlargement after definitive chemoradiotherapy for clinical stage I esophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1186/1476-4598-12-94openalex-snapshot
Non-small cell lung cancer cells survived ionizing radiation treatment display cancer stem cell and epithelial-mesenchymal transition phenotypes
inferredcites →https://doi.org/10.1186/1748-717x-8-241openalex-snapshot
Three-dimensional conformal radiotherapy with concurrent chemotherapy for postoperative recurrence of esophageal squamous cell carcinoma: clinical efficacy and failure pattern
inferredcites →https://doi.org/10.1186/1748-717x-8-31openalex-snapshot
XRCC1 codon 399Gln polymorphism is associated with radiotherapy-induced acute dermatitis and mucositis in nasopharyngeal carcinoma patients
inferredcites →https://doi.org/10.1186/s12885-016-2656-8openalex-snapshot
An evaluation in vitro of PARP-1 inhibitors, rucaparib and olaparib, as radiosensitisers for the treatment of neuroblastoma
inferredcites →https://doi.org/10.1186/s12885-019-6312-yopenalex-snapshot
Aurora-a confers radioresistance in human hepatocellular carcinoma by activating NF-κB signaling pathway
inferredcites →https://doi.org/10.1186/s12935-015-0221-1openalex-snapshot
Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp
inferredcites →https://doi.org/10.1186/s12935-020-01357-xopenalex-snapshot
Palbociclib treatment alters nucleotide biosynthesis and glutamine dependency in A549 cells
inferredcites →https://doi.org/10.1186/s12967-015-0464-6openalex-snapshot
FH535 increases the radiosensitivity and reverses epithelial-to-mesenchymal transition of radioresistant esophageal cancer cell line KYSE-150R
inferredcites →https://doi.org/10.1186/s13014-015-0534-1openalex-snapshot
RETRACTED ARTICLE: IL-6 signaling promotes DNA repair and prevents apoptosis in CD133+ stem-like cells of lung cancer after radiation
inferredcites →https://doi.org/10.1186/s13045-016-0290-1openalex-snapshot
EGFR C797S mutation mediates resistance to third-generation inhibitors in T790M-positive non-small cell lung cancer
inferredcites →https://doi.org/10.1186/s13046-019-1314-9openalex-snapshot
Exosomal transfer of p-STAT3 promotes acquired 5-FU resistance in colorectal cancer cells
inferredcites →https://doi.org/10.1186/s13046-019-1405-7openalex-snapshot
The JAK2/STAT3/CCND2 Axis promotes colorectal Cancer stem cell persistence and radioresistance
inferredcites →https://doi.org/10.1186/s40170-020-0209-8openalex-snapshot
Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma
inferredcites →https://doi.org/10.1186/s40779-018-0167-4openalex-snapshot
Biological effects of radiation on cancer cells
inferredcites →https://doi.org/10.1200/jco.2004.01.120openalex-snapshot
Clinical Cardiac Tolerability of Trastuzumab
inferredcites →https://doi.org/10.1200/jco.2004.08.009openalex-snapshot
Four Decades of Continuing Innovation With Fluorouracil: Current and Future Approaches to Fluorouracil Chemoradiation Therapy
inferredcites →https://doi.org/10.1200/jco.2007.15.1829openalex-snapshot
Survival of the Fittest: Cancer Stem Cells in Therapeutic Resistance and Angiogenesis
inferredcites →https://doi.org/10.1200/jco.2016.69.0032openalex-snapshot
Cell-Cycle Therapeutics Come of Age
inferredcites →https://doi.org/10.1203/00006450-199703000-00022openalex-snapshot
The Transcription of the XRCC1 Gene in the Heart of Radiation-Resistant and Radiation-Sensitive Mice after Ionizing Irradiation
inferredcites →https://doi.org/10.1269/jrr.11148openalex-snapshot
Beclin1-induced Autophagy Abrogates Radioresistance of Lung Cancer Cells by Suppressing Osteopontin
inferredcites →https://doi.org/10.1371/journal.pone.0055820openalex-snapshot
Bmi1 Enhances Tumorigenicity and Cancer Stem Cell Function in Pancreatic Adenocarcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0070473openalex-snapshot
Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking
inferredcites →https://doi.org/10.1371/journal.pone.0125402openalex-snapshot
EGCG Enhances Cisplatin Sensitivity by Regulating Expression of the Copper and Cisplatin Influx Transporter CTR1 in Ovary Cancer
inferredcites →https://doi.org/10.1371/journal.pone.0126149openalex-snapshot
Fractionated Ionizing Radiation Promotes Epithelial-Mesenchymal Transition in Human Esophageal Cancer Cells through PTEN Deficiency-Mediated Akt Activation
inferredcites →https://doi.org/10.14989/doctor.k19597openalex-snapshot
Novel 5-fluorouracil-resistant human esophageal squamous cell carcinoma cells with dihydropyrimidine dehydrogenase overexpression.
inferredcites →https://doi.org/10.1517/14656566.2013.801454openalex-snapshot
Treatment options for esophageal squamous cell carcinoma
inferredcites →https://doi.org/10.1517/14712590902735795openalex-snapshot
Mechanisms of tumor resistance to EGFR-targeted therapies
inferredcites →https://doi.org/10.15171/apb.2017.041openalex-snapshot
The Different Mechanisms of Cancer Drug Resistance: A Brief Review
inferredcites →https://doi.org/10.15761/icst.1000243openalex-snapshot
Epithelial-mesenchymal transition in cancer: An overview
inferredcites →https://doi.org/10.1586/14737159.8.6.761openalex-snapshot
XRCC1polymorphism and lung cancer risk
inferredcites →https://doi.org/10.1586/era.10.226openalex-snapshot
HER2-amplified breast cancer: mechanisms of trastuzumab resistance and novel targeted therapies
inferredcites →https://doi.org/10.1586/era.11.201openalex-snapshot
Molecular mechanisms of cisplatin resistance in bladder cancer
inferredcites →https://doi.org/10.1590/s1415-475738420150019openalex-snapshot
Ionizing radiation-induced DNA injury and damage detection in patients with breast cancer
showing the first 200 of 261 · page through all 261

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4776527openalex-extracted
Targeting Radiation Resistance in Oesophageal Adenocarcinoma Through Manipulation of Energy Metabolism and Neo-Angiogenesis Using Pyrazinib Coupled with Gold Nanoparticles
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Physical Health Decline After Chemotherapy or Endocrine Therapy in Breast Cancer Survivors
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Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA ‐seq datasets
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Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells
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Chemo‐Herbal Combination Drug Delivery for Cancer Management
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Protein Degradation Nanoparticles for Intraoperative Fluorescence Diagnosis and Postoperative Adjuvant Therapy of Solid Tumors
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A20 Facilitates Oxaliplatin Sensitivity in Colorectal Cancer Through Monoubiquitylation of IKK‐β
inferred← citeshttps://doi.org/10.1002/advs.75844openalex-snapshot
mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer
inferred← citeshttps://doi.org/10.1002/ardp.70291openalex-snapshot
1,2,3‐Triazole‐Linked Chalcones as Privileged Scaffolds in Anticancer Agents
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Protective Effect of Biochanin A on Gamma Radiation‐Induced Oxidative Stress, Antioxidant Status, Apoptotic, and DNA Repairing Molecules in Swiss Albino Mice
inferred← citeshttps://doi.org/10.1002/jbt.70962openalex-snapshot
Natural Products and Long Noncoding RNAs: A Complex Regulatory Network in Pancreatic Cancer Progression and Treatment
inferred← citeshttps://doi.org/10.1002/jcb.30383openalex-snapshot
Conditioned media from human pluripotent stem cell‐derived cardiomyocytes inhibit the growth and migration of lung cancer cells
inferred← citeshttps://doi.org/10.1002/jcb.30488openalex-snapshot
The role of p62 in cell death and survival of 5‐fluorouracil and oxaliplatin‐resistant colorectal cancer cells
inferred← citeshttps://doi.org/10.1002/jso.26880openalex-snapshot
Current and future strategies for radiation therapy in gastric cancer
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Gene and RNA Editing: Revolutionary Approaches to Treating Diseases
inferred← citeshttps://doi.org/10.1002/mco2.70452openalex-snapshot
Human Endogenous Retroviruses and Diseases
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Mathematical Modeling and Optimal Control of Combined Virotherapy and Adoptive T Cell Therapy for Cancer Treatment
inferred← citeshttps://doi.org/10.1002/slct.202402105openalex-snapshot
Identification of Potential Inhibitors for Poly(ADP‐ribose) Polymerase‐10 (PARP10): Virtual Screening, Molecular Docking, and Molecular Dynamics Simulations
inferred← citeshttps://doi.org/10.1002/smsc.202400298openalex-snapshot
Radiolabeled Nanogels: From Multimodality Imaging to Combination Therapy of Cancer
inferred← citeshttps://doi.org/10.1002/smtd.202500617openalex-snapshot
Comprehensive Osteosarcoma Treatment with Multifunctional Composite Hydrogels Enabling Combined Photothermal Cancer Ablation and Osteoinductive Tissue Regeneration
inferred← citeshttps://doi.org/10.1002/wnan.1876openalex-snapshot
Innovative nanotheranostics: Smart nanoparticles based approach to overcome breast cancer stem cells mediated chemo‐ and radioresistances
inferred← citeshttps://doi.org/10.1002/wnan.1984openalex-snapshot
Chemoradiotherapy and nanomedicine: Drug mechanisms and delivery systems
inferred← citeshttps://doi.org/10.1007/978-3-031-18810-7_5openalex-snapshot
Clinical Radiobiology for Radiation Oncology
inferred← citeshttps://doi.org/10.1007/978-3-031-66686-5_2openalex-snapshot
Tumor Microenvironment and Epigenetic Implications in Breast Cancer Progression
inferred← citeshttps://doi.org/10.1007/978-3-031-86185-7_1openalex-snapshot
Advances in Cancer Vaccines: From Traditional Platforms to Nanotechnology Innovations
inferred← citeshttps://doi.org/10.1007/978-3-032-03288-1_10openalex-snapshot
Nanotherapeutics for Breast Cancer with Metal Nanocomposites
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Accidental Cytogenetic and Molecular Biodosimetry in Radiation Emergency
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The Microbiome, Cancer, and Health Disparities: Implications for Native American Communities in the Southwest
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Mechanistic Role of Long Non-coding RNAs in Drug and Radiotherapy Resistance of Cancer Cells
inferred← citeshttps://doi.org/10.1007/978-981-95-5989-3_8openalex-snapshot
Development of Resistance in Tumor for the Available Conventional Therapies
inferred← citeshttps://doi.org/10.1007/978-981-95-7358-5_21openalex-snapshot
Challenges and Opportunities
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Mechanisms of Cancer Resistance to Various Therapies
inferred← citeshttps://doi.org/10.1007/s00432-023-04592-7openalex-snapshot
Mitochondrial metabolism: a predictive biomarker of radiotherapy efficacy and toxicity
inferred← citeshttps://doi.org/10.1007/s00432-024-05757-8openalex-snapshot
A perspective on tumor radiation resistance following high-LET radiation treatment
inferred← citeshttps://doi.org/10.1007/s00432-024-06044-2openalex-snapshot
Response to induction chemotherapy as a prognostic indicator in locally advanced head and neck squamous cell carcinoma
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A review on CRISPR/Cas: a versatile tool for cancer screening, diagnosis, and clinic treatment
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Autophagy-based therapy for hepatocellular carcinoma: from standard treatments to combination therapy, oncolytic virotherapy, and targeted nanomedicines
inferred← citeshttps://doi.org/10.1007/s10238-024-01532-8openalex-snapshot
Long non-coding RNAs (lncRNAs) in cancer development: new insight from STAT3 signaling pathway to immune evasion
inferred← citeshttps://doi.org/10.1007/s10388-024-01097-1openalex-snapshot
Optimizing neoadjuvant radiotherapy for locally advanced esophageal squamous cell carcinoma: a comprehensive review on the role of concomitant or sequential immune checkpoint inhibitors
inferred← citeshttps://doi.org/10.1007/s10555-023-10148-5openalex-snapshot
Prospects of earthworm coelomic fluid as a potential therapeutic agent to treat cancer
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Molecular mechanisms of sensitivity and resistance to radiotherapy
inferred← citeshttps://doi.org/10.1007/s10735-025-10533-0openalex-snapshot
Mitochondrial CLK2 promotes chemotherapy resistance in colorectal Cancer by regulating oxidative phosphorylation and ferroptosis
inferred← citeshttps://doi.org/10.1007/s10853-026-12630-1openalex-snapshot
Dopamine-loaded manganese gallate diagnostic nanoplatform for MRI-guided synergistic photothermal and chemodynamic cancer therapy
inferred← citeshttps://doi.org/10.1007/s10895-023-03145-yopenalex-snapshot
The Determination of Cisplatin and Luteolin Synergistic Effect on Colorectal Cancer Cell Apoptosis and Mitochondrial Dysfunction by Fluorescence Labelling
inferred← citeshttps://doi.org/10.1007/s11033-023-08864-wopenalex-snapshot
Defining new biomarkers for overcoming therapeutical resistance in cervical cancer using lncRNA
inferred← citeshttps://doi.org/10.1007/s11517-024-03233-6openalex-snapshot
Artificial blood—hope and the challenges to combat tumor hypoxia for anti-cancer therapy
inferred← citeshttps://doi.org/10.1007/s12010-024-05084-1openalex-snapshot
Tripartite Motif Containing 71 Suppresses Tumor Growth by Down-Regulating eIF5A2 Expression in Laryngeal Squamous Cell Carcinoma
inferred← citeshttps://doi.org/10.1007/s12032-023-01948-4openalex-snapshot
Revamping the innate or innate-like immune cell-based therapy for hepatocellular carcinoma: new mechanistic insights and advanced opportunities
inferred← citeshttps://doi.org/10.1007/s12032-023-01997-9openalex-snapshot
Molecular mechanisms augmenting resistance to current therapies in clinics among cervical cancer patients
inferred← citeshttps://doi.org/10.1007/s12032-024-02586-0openalex-snapshot
GRP78 as a potential therapeutic target in cancer treatment: an updated review of its role in chemoradiotherapy resistance of cancer cells
inferred← citeshttps://doi.org/10.1007/s12032-025-02607-6openalex-snapshot
Autophagy induced by metabolic processes leads to solid tumor cell metastatic dormancy and recurrence
inferred← citeshttps://doi.org/10.1007/s12032-025-02629-0openalex-snapshot
From conventional to cutting edge: an exploration of osteosarcoma treatments
inferred← citeshttps://doi.org/10.1007/s12032-025-02667-8openalex-snapshot
Targeting TGF-β: a promising strategy for cancer therapy
inferred← citeshttps://doi.org/10.1007/s12032-025-02889-wopenalex-snapshot
LINC01410 in cancer: a comprehensive review of its oncogenic role, regulatory mechanisms, and clinical implications
inferred← citeshttps://doi.org/10.1007/s12032-025-03098-1openalex-snapshot
Static magnetic field and alternating magnetic field cytotoxic effects on triple negative breast cancer cell line (MDA-MB-231)
inferred← citeshttps://doi.org/10.1007/s12032-026-03251-4openalex-snapshot
Natural simple coumarins and their interaction with AKR1C3: implications for overcoming chemoradioresistance in gastrointestinal carcinomas
inferred← citeshttps://doi.org/10.1007/s12190-024-02139-8openalex-snapshot
Assessing the impact of immunotherapy on oncolytic virotherapy in the treatment of cancer
inferred← citeshttps://doi.org/10.1007/s12602-026-11189-2openalex-snapshot
Gut Limosilactobacillus reuteri-secreted Components Mitigate Susceptibility to Radiation by Alleviating Oxidative Stress in the Intestinal Epithelium
inferred← citeshttps://doi.org/10.1007/s12668-025-01829-2openalex-snapshot
Development and Characterization of Genistein-Loaded Silver Nanoparticles for the Induction of Apoptosis on Human Hepatocellular Carcinoma Cell Lines
inferred← citeshttps://doi.org/10.1007/s12672-024-00882-9openalex-snapshot
Research progress of Paris polyphylla in the treatment of digestive tract cancers
inferred← citeshttps://doi.org/10.1007/s12672-025-02150-wopenalex-snapshot
Hypoxia signaling in cancer: HIF-1α stimulated by COVID-19 can lead to cancer progression and chemo-resistance in oral squamous cell carcinoma (OSCC)
inferred← citeshttps://doi.org/10.1007/s12672-026-04587-zopenalex-snapshot
Synthetic lethality and DNA damage response targeting in cancer stem cells: a comprehensive review
inferred← citeshttps://doi.org/10.1007/s12672-026-04812-9openalex-snapshot
Genomic profiling enables personalized strategies to overcome drug resistance in multiple myeloma
inferred← citeshttps://doi.org/10.1007/s13205-023-03826-2openalex-snapshot
Understanding immune checkpoints and PD-1/PD-L1-mediated immune resistance towards tumour immunotherapy
inferred← citeshttps://doi.org/10.1007/s13402-026-01206-5openalex-snapshot
Role of DDX39A in modulating the tumor progression and radiosensitivity in esophageal squamous cell carcinoma
inferred← citeshttps://doi.org/10.1007/s40496-023-00353-0openalex-snapshot
Effectiveness of SAMITAL® for Management of Chemo/Radiotherapy-Induced Oral Mucositis in Patients with Cancer—a Systematic Review
inferred← citeshttps://doi.org/10.1007/s40883-025-00437-6openalex-snapshot
A Study on the Potential of Curcumin in Proliferation and Apoptosis of SW480 and SW620 Colon Cancer Cell Lines
inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00167-4openalex-snapshot
The Immune System in Nephrotoxicity
inferred← citeshttps://doi.org/10.1016/b978-0-443-15177-4.00013-3openalex-snapshot
Advancements in stem cell-based therapeutics in phospholipase A2-dependent colorectal cancer
inferred← citeshttps://doi.org/10.1016/b978-0-443-22253-5.00025-xopenalex-snapshot
Magnetotheranostics
inferred← citeshttps://doi.org/10.1016/b978-0-443-23516-0.00109-4openalex-snapshot
Radiation Fibrosis Syndrome
inferred← citeshttps://doi.org/10.1016/b978-0-443-28985-9.00004-5openalex-snapshot
Future directions in cervical cancer treatment
inferred← citeshttps://doi.org/10.1016/b978-0-443-31592-3.00017-0openalex-snapshot
Role of AI in molecular cancer pharmacology
inferred← citeshttps://doi.org/10.1016/b978-0-443-33349-1.00009-0openalex-snapshot
Breast cancer stem cell targeting
inferred← citeshttps://doi.org/10.1016/bs.ircmb.2023.07.008openalex-snapshot
Epigenetics as a determinant of radiation response in cancer
inferred← citeshttps://doi.org/10.1016/j.actbio.2026.04.002openalex-snapshot
Bovine serum albumin-stabilized nano-delivery system potentiates targeted anti-angiogenic therapy and synergistic photo-immunotherapy to restrict lung cancer metastasis
inferred← citeshttps://doi.org/10.1016/j.addr.2025.115676openalex-snapshot
Nitric oxide releasing graphene for next-generation therapeutics
inferred← citeshttps://doi.org/10.1016/j.addr.2026.115937openalex-snapshot
Redox-activated heavy-atom-free photosensitizers for enhanced photodynamic cancer therapy
inferred← citeshttps://doi.org/10.1016/j.apsb.2026.03.054openalex-snapshot
Engineered extracellular vesicles for combinatorial cancer therapy and imaging
inferred← citeshttps://doi.org/10.1016/j.arr.2025.102786openalex-snapshot
“Aging and epigenetic implications in radiotherapy: The promise of BNCT”
inferred← citeshttps://doi.org/10.1016/j.bbadis.2025.167759openalex-snapshot
MiRNA affects the advancement of breast cancer by modulating the immune system's response
inferred← citeshttps://doi.org/10.1016/j.bbadis.2025.168125openalex-snapshot
Vimentin-targeting adaptogen withaferin A: Potential to selectively suppress cervical cancer – Single-cell microspectroscopic and molecular analysis
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.09.032openalex-snapshot
Doxorubicin-induced senescence promotes resistance to cell death by modulating genes associated with apoptotic and necrotic pathways in prostate cancer DU145 CD133+/CD44+ cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152129openalex-snapshot
Norcantharidin-loaded liposomes potentiate radiotherapy by reprogramming tumor vasculature toward normalization
inferred← citeshttps://doi.org/10.1016/j.bcp.2024.116472openalex-snapshot
Novel curcumin derivatives N17 exert anti-cancer effects through the CSNK1G3/AKT axis in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2023.05.010openalex-snapshot
Combination of bacterial-targeted delivery of gold-based AIEgen radiosensitizer for fluorescence-image-guided enhanced radio-immunotherapy against advanced cancer
inferred← citeshttps://doi.org/10.1016/j.bioadv.2025.214366openalex-snapshot
Biotinylated nanoparticles: A new frontier in nanomedicine and targeted cancer therapy
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2026.123993openalex-snapshot
Harnessing the HMnO2 nanoparticles as the DNA injury amplifier to improve the OXA-based trans-artery infusion chemotherapy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106721openalex-snapshot
Small-molecule dual inhibitors targeting heat shock protein 90 for cancer targeted therapy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.108582openalex-snapshot
Targets and promising adjuvants for improving breast tumor response to radiotherapy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2026.109562openalex-snapshot
Rational design of 2-substituted thio-7-chloroquinazolin-4(3H)-one derivatives as dual EGFR/VEGFR-2 inhibitors with broad-Spectrum anticancer and apoptotic activities
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.114487openalex-snapshot
Autophagy orchestrates resistance in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.116668openalex-snapshot
Radiosensitizing effects of heparinized magnetic iron oxide nanoparticles in colon cancer
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117458openalex-snapshot
The roles of lncRNAs in the development of drug resistance of oral cancers
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118364openalex-snapshot
Therapeutic challenges in breast cancer: Navigating the impact of oxidative stress on treatment efficacy and toxicity
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118715openalex-snapshot
Fuelling resistance: Lipid metabolic rewiring in cancer response to chemotherapy and radiotherapy
inferred← citeshttps://doi.org/10.1016/j.bone.2025.117446openalex-snapshot
Marrow adipogenic lineage precursors (MALPs) facilitate bone marrow recovery after chemotherapy
inferred← citeshttps://doi.org/10.1016/j.canlet.2025.217612openalex-snapshot
SLC7A5/E2F1/PTBP1/PKM2 axis mediates progression and therapy effect of triple-negative breast cancer through the crosstalk of amino acid metabolism and glycolysis pathway
inferred← citeshttps://doi.org/10.1016/j.canlet.2026.218777openalex-snapshot
Pharmacologic inhibition of SOX9-CDK4 by CYD-4-61 impairs gastric adenocarcinoma growth and amplifies anti-PD-1 response
inferred← citeshttps://doi.org/10.1016/j.canrad.2022.06.019openalex-snapshot
DNA repair inhibitors and radiotherapy
inferred← citeshttps://doi.org/10.1016/j.carbpol.2025.123454openalex-snapshot
Advanced therapeutic strategies using Thermo-sensitive chitosan/pectin hydrogel in the treatment of multiple cancers
inferred← citeshttps://doi.org/10.1016/j.cmpb.2023.107884openalex-snapshot
Deep reinforcement learning-based control of chemo-drug dose in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2025.115022openalex-snapshot
Dye-loaded hybrid core-shell gold nanoparticles for sensitized singlet oxygen production in radiotherapy
inferred← citeshttps://doi.org/10.1016/j.cpt.2025.01.006openalex-snapshot
Biomarkers, isolation methods, and therapeutic implications of breast cancer stem cells
inferred← citeshttps://doi.org/10.1016/j.craph.2026.100089openalex-snapshot
Radioprotective effect of pyrogallol nanocomposite on radiation-induced toxicity in spleen and bone marrow of BALB/c mice
inferred← citeshttps://doi.org/10.1016/j.crbiot.2025.100330openalex-snapshot
Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2023.103967openalex-snapshot
Exosomes derived from cancer-associated fibroblasts mediate response to cancer therapy
inferred← citeshttps://doi.org/10.1016/j.ctrv.2025.102939openalex-snapshot
Enhancing radiotherapy techniques for Triple-Negative breast cancer treatment
inferred← citeshttps://doi.org/10.1016/j.drup.2024.101116openalex-snapshot
A distinct subset of urothelial cells with enhanced EMT features promotes chemotherapy resistance and cancer recurrence by increasing COL4A1-ITGB1 mediated angiogenesis
inferred← citeshttps://doi.org/10.1016/j.ejphar.2023.175991openalex-snapshot
Strategy of targeting the tumor microenvironment via inhibition of fibroblast/fibrosis remodeling new era to cancer chemo-immunotherapy resistance
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.177222openalex-snapshot
Oral cancer stem cells: A comprehensive review of key drivers of treatment resistance and tumor recurrence
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177965openalex-snapshot
Reactivating apoptotic pathways in cancer: A review of novel therapeutic approaches
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e19147openalex-snapshot
Chimeric antigen receptor-modified T cells therapy in prostate cancer: A comprehensive review on the current state and prospects
inferred← citeshttps://doi.org/10.1016/j.ica.2024.122456openalex-snapshot
Computational analysis of molecular details on the interaction of C,N-cyclometalated 2H-indazole Ru(II) and Ir(III) complexes with cancer protein targets
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2026.127383openalex-snapshot
Cell targeting peptide guided nanomedicine: a new paradigm in precision oncology for the management of non-small cell lung cancer
inferred← citeshttps://doi.org/10.1016/j.ijpx.2025.100419openalex-snapshot
Advancing cancer radiotherapy: Harnessing radiosensitizers and nanotechnology for enhanced tumor control
inferred← citeshttps://doi.org/10.1016/j.ijrobp.2026.04.023openalex-snapshot
Aly as a Key Regulator of DNA Repair and Immune Evasion in Esophageal Squamous Cell Carcinoma Radioresistance
inferred← citeshttps://doi.org/10.1016/j.isci.2023.106684openalex-snapshot
Creatine kinase brain-type regulates BCAR1 phosphorylation to facilitate DNA damage repair
inferred← citeshttps://doi.org/10.1016/j.jchromb.2026.125145openalex-snapshot
Oridonin and ponicidin induce GSDME-mediated pyroptosis in pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.jconrel.2023.12.032openalex-snapshot
Autophagy-modulating biomembrane nanostructures: A robust anticancer weapon by modulating the inner and outer cancer environment
inferred← citeshttps://doi.org/10.1016/j.jddst.2023.105165openalex-snapshot
Apigenin and its nanoformulations for ameliorating normal tissue toxicity and enhancing tumor response to therapy: A mechanistic viewpoint
inferred← citeshttps://doi.org/10.1016/j.jddst.2025.106798openalex-snapshot
Gene therapy with gene delivery systems and therapeutic strategies: A new frontier in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108571openalex-snapshot
Pharmacokinetics and toxicological investigations of novel magneto-liposomes (T-LMD) for αvβ3 integrin targeted doxorubicin chemotherapy of solid tumors
inferred← citeshttps://doi.org/10.1016/j.jddst.2026.108710openalex-snapshot
Encapsulation of hemin chloride and doxorubicin in two-compartment polycaprolactone micro- and nanoparticles for sequential redox priming and enhanced lung cancer treatment
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116472openalex-snapshot
Prosopis juliflora (Sw.) DC phytochemicals induce apoptosis and inhibit cell proliferation signaling pathways, EMT, migration, invasion, angiogenesis and stem cell markers in melanoma cell lines
inferred← citeshttps://doi.org/10.1016/j.jksus.2024.103410openalex-snapshot
Deciphering the effect of Potentilla fulgens root extract against healthy HUVEC cell line and cancer cell lines (A549 and SKOV-3)
inferred← citeshttps://doi.org/10.1016/j.jrras.2026.102291openalex-snapshot
Integrated transcriptomic profiling identifies a core gene signature associated with melanoma progression and radiotherapy-related immune suppression
inferred← citeshttps://doi.org/10.1016/j.jtcme.2024.04.003openalex-snapshot
Exploring the ROS-mediated anti-cancer potential in human triple-negative breast cancer by garlic bulb extract: A source of therapeutically active compounds
inferred← citeshttps://doi.org/10.1016/j.jtho.2024.11.003openalex-snapshot
DSTYK Inhibition Sensitizes NSCLC to Taxane-Based Chemotherapy
inferred← citeshttps://doi.org/10.1016/j.jval.2024.09.008openalex-snapshot
Slipping Away: Slippage in Hazard Ratios Over Datacuts and Its Impact on Immuno-oncology Combination Economic Evaluations
inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120656openalex-snapshot
Could allicin alleviate trastuzumab-induced cardiotoxicity in a rat model through antioxidant, anti-inflammatory, and antihyperlipidemic properties?
inferred← citeshttps://doi.org/10.1016/j.matbio.2025.05.003openalex-snapshot
Interactions between cancer-associated fibroblasts and the extracellular matrix in oesophageal cancer
inferred← citeshttps://doi.org/10.1016/j.matdes.2026.116726openalex-snapshot
The role and mechanism of magnetic hydrogels in bone diseases
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.140255openalex-snapshot
Effect of N-substituted aliphatic glycine presence on bioactivity, cytotoxicity, and selectivity of Pt(II) and Pd(II) complexes in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.145215openalex-snapshot
Illuminating anticancer pathways with pyrene Schiff bases: Bridging simulations and experiments
inferred← citeshttps://doi.org/10.1016/j.nantod.2025.102816openalex-snapshot
Engineering hydroxyapatite nanocrystals for cancer nanomedicine through ion substitution: Advances and prospects
inferred← citeshttps://doi.org/10.1016/j.neurot.2024.e00498openalex-snapshot
PET in neurotherapeutic discovery and development
inferred← citeshttps://doi.org/10.1016/j.nexres.2025.100179openalex-snapshot
Nanotechnology and artificial intelligence in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.nxnano.2026.100741openalex-snapshot
The inspiration of CRISPR-Cas: Interface of nature with a pharmacy: A compatible horizon of cancer treatment
inferred← citeshttps://doi.org/10.1016/j.omtn.2023.102053openalex-snapshot
Tumor-targeted delivery of lnc antisense RNA against RCAS1 by live-attenuated tryptophan-auxotrophic Salmonella inhibited 4T1 breast tumors and metastasis in mice
inferred← citeshttps://doi.org/10.1016/j.omtn.2026.103064openalex-snapshot
miRNA-34a-5p is a novel biomarker and modulator of the radioresponse in esophageal adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.phrs.2022.106418openalex-snapshot
Long non-coding RNA (lncRNA) H19 in human cancer: From proliferation and metastasis to therapy
inferred← citeshttps://doi.org/10.1016/j.phrs.2026.108317openalex-snapshot
Artesunate as an emerging anticancer modality: Insights and advances
inferred← citeshttps://doi.org/10.1016/j.phymed.2022.154369openalex-snapshot
Modulation of diverse oncogenic signaling pathways by oroxylin A: An important strategy for both cancer prevention and treatment
inferred← citeshttps://doi.org/10.1016/j.phyplu.2025.100730openalex-snapshot
Assessing the influence of matcha green tea extract on NF-κB/MAPK signaling pathway activation in rats: A study on irradiation-induced acute hepatic inflammatory response
inferred← citeshttps://doi.org/10.1016/j.procbio.2024.03.004openalex-snapshot
Fabrication of etoposide-loaded folic-acid-clocked mesoporous nanoparticles: Investigation of lung cancer proliferation and induction of apoptosis and ferroptosis
inferred← citeshttps://doi.org/10.1016/j.prp.2023.154990openalex-snapshot
The mechanistic role of NAT10 in cancer: Unraveling the enigmatic web of oncogenic signaling
inferred← citeshttps://doi.org/10.1016/j.prp.2023.154999openalex-snapshot
Recent progress and the emerging role of lncRNAs in cancer drug resistance; focusing on signaling pathways
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155293openalex-snapshot
Regulation of cellular responses to X-ray irradiation through the activation of lysophosphatidic acid (LPA) receptor-3 (LPA3) and LPA2 in osteosarcoma cells
inferred← citeshttps://doi.org/10.1016/j.prp.2024.155523openalex-snapshot
The paradox of autophagy in cancer: NEAT1's role in tumorigenesis and therapeutic resistance
inferred← citeshttps://doi.org/10.1016/j.redox.2022.102503openalex-snapshot
The pro- and anti-tumoral properties of gap junctions in cancer and their role in therapeutic strategies
inferred← citeshttps://doi.org/10.1016/j.semradonc.2021.09.004openalex-snapshot
Oncometabolites as Regulators of DNA Damage Response and Repair
inferred← citeshttps://doi.org/10.1016/j.tice.2024.102624openalex-snapshot
Targeting cancer-associated fibroblasts with pirfenidone: A novel approach for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.tjnut.2025.09.035openalex-snapshot
Dietary Supplement Use and Life Expectancy After Breast Cancer–The Danish Diet, Cancer and Health Cohort
inferred← citeshttps://doi.org/10.1016/j.tranon.2024.102023openalex-snapshot
Inhibition of STAT3: A promising approach to enhancing the efficacy of chemotherapy in medulloblastoma
inferred← citeshttps://doi.org/10.1016/j.tranon.2026.102918openalex-snapshot
Identification and functional validation of a four-gene signature associated with radiotherapy resistance in oral squamous cell carcinoma
inferred← citeshttps://doi.org/10.1016/j.ucl.2026.02.005openalex-snapshot
Modern Radiotherapy for High-Risk and Very-High-Risk Prostate Adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.ultrasmedbio.2026.02.011openalex-snapshot
A Non-Invasive Combined Photothermal-Sonodynamic Therapy Using a Dual-Activated TiO2-Au Nanohybrid: A Competitive Alternative to the Invasive Radiotherapy
inferred← citeshttps://doi.org/10.1016/j.yexcr.2024.114153openalex-snapshot
Solasodine targets NF-κB signaling to overcome P-glycoprotein mediated multidrug resistance in cancer
inferred← citeshttps://doi.org/10.1016/j.ygyno.2025.03.030openalex-snapshot
ECPPF stratification identifies occult high-risk subgroups in stage I, grade 1 or 2, ≤50 % invasive endometrial cancer: Candidates for adjuvant therapy
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.4c00149openalex-snapshot
Development of Novel Phosphonodifluoromethyl-Containing Phosphotyrosine Mimetics and a First-In-Class, Potent, Selective, and Bioavailable Inhibitor of Human CDC14 Phosphatases
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.5c00043openalex-snapshot
Radionuclide-Aided Improvement of the Therapeutic Efficacy of Novel Antibody–Drug Conjugates against HER2-Expressing Cancers
inferred← citeshttps://doi.org/10.1021/acsabm.4c01978openalex-snapshot
Iron Oxide Nanoparticles as Enhancers for Radiotherapy of Tumors
inferred← citeshttps://doi.org/10.1021/acsabm.5c00123openalex-snapshot
Synergy of Microfluidics and Nanomaterials: A Revolutionary Approach for Cancer Management
inferred← citeshttps://doi.org/10.1021/acsanm.3c04714openalex-snapshot
Nanotechnology Meets Stem Cell Therapy for Treating Glioblastomas: A Review
inferred← citeshttps://doi.org/10.1021/acsbiomaterials.4c00897openalex-snapshot
Nanomedicines with Versatile GSH-Responsive Linkers for Cancer Theranostics
inferred← citeshttps://doi.org/10.1021/acsnano.3c00269openalex-snapshot
Radiation-Triggered Selenium-Engineered Mesoporous Silica Nanocapsules for RNAi Therapy in Radiotherapy-Resistant Glioblastoma
inferred← citeshttps://doi.org/10.1021/acsnano.5c18874openalex-snapshot
Molecular Engineering of Curcumin-Based Lysosome-Targeting Photosensitizers for Boosting Tumor Photoimmunotherapy via Ferroptosis/Pyroptosis Activation and Autophagy Inhibition
inferred← citeshttps://doi.org/10.1021/acsomega.2c07356openalex-snapshot
Exploring SPK98 for the Selective Sensitization of ATM- or P53-Deficient Cancer Cells
inferred← citeshttps://doi.org/10.1021/acsptsci.3c00198openalex-snapshot
Differential Expression of SRY-Related HMG-Box Transcription Factor 2, Oligodendrocyte Lineage Transcription Factor 2, and Zinc Finger E-Box Binding Homeobox 1 in Serum-Derived Extracellular Vesicles: Implications for Mithramycin Sensitivity and Targeted Therapy in High-Grade Glioma
inferred← citeshttps://doi.org/10.1021/acsptsci.3c00279openalex-snapshot
Opposing Interplay between Nuclear Factor Erythroid 2-Related Factor 2 and Forkhead BoxO 1/3 is Responsible for Sepantronium Bromide’s Poor Efficacy and Resistance in Cancer cells: Opportunity for Combination Therapy in Triple Negative Breast Cancer
inferred← citeshttps://doi.org/10.1038/s41388-023-02628-3openalex-snapshot
N4-acetylcytidine modification of lncRNA CTC-490G23.2 promotes cancer metastasis through interacting with PTBP1 to increase CD44 alternative splicing
inferred← citeshttps://doi.org/10.1038/s41388-023-02935-9openalex-snapshot
TKT-PARP1 axis induces radioresistance by promoting DNA double-strand break repair in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1038/s41392-025-02184-0openalex-snapshot
Ultra-high dose rate radiotherapy overcomes radioresistance in head and neck squamous cell carcinoma
inferred← citeshttps://doi.org/10.1038/s41392-025-02266-zopenalex-snapshot
Targeting epigenetic regulators as a promising avenue to overcome cancer therapy resistance
inferred← citeshttps://doi.org/10.1038/s41401-024-01233-8openalex-snapshot
Clobetasol propionate, a Nrf-2 inhibitor, sensitizes human lung cancer cells to radiation-induced killing via mitochondrial ROS-dependent ferroptosis
inferred← citeshttps://doi.org/10.1038/s41419-025-07959-5openalex-snapshot
Pharmacological activation of SIRT6 suppresses progression of head and neck and esophageal squamous cell carcinoma by modulation of cellular metabolism and protein translation
inferred← citeshttps://doi.org/10.1038/s41467-023-35856-yopenalex-snapshot
Niche stiffness sustains cancer stemness via TAZ and NANOG phase separation
inferred← citeshttps://doi.org/10.1038/s41598-024-78958-3openalex-snapshot
Preparation and characterization of calcium-doped graphene oxide-chitosan Nanocarrier to enhance the gene delivery in MCF-7 cell line
inferred← citeshttps://doi.org/10.1038/s41598-025-87635-yopenalex-snapshot
Curcumin nanoparticles alleviate brain mitochondrial dysfunction and cellular senescence in γ-irradiated rats
inferred← citeshttps://doi.org/10.1038/s44385-026-00075-9openalex-snapshot
Use of in vitro co-culture models to inform bacterial engineering for the treatment of solid tumours
inferred← citeshttps://doi.org/10.1039/d3ma00629hopenalex-snapshot
Circumventing challenges in mitochondrial targeting for cancer treatment: leveraging nanoplatforms for effective solutions
inferred← citeshttps://doi.org/10.1039/d5md00361jopenalex-snapshot
EGFR AP : a predictive machine learning model for assessing small molecule activity against the epidermal growth factor receptor
inferred← citeshttps://doi.org/10.1080/07435800.2024.2361152openalex-snapshot
Additional considerations in cancer cell radioresistance, integrin αvβ3 and thyroid hormones
inferred← citeshttps://doi.org/10.1080/08830185.2026.2614779openalex-snapshot
Comprehensive review on immunotherapy for hepatocellular carcinoma: Current status and future perspectives
inferred← citeshttps://doi.org/10.1080/09291016.2026.2686670openalex-snapshot
Multimodal effects of cilengitide on circadian clock gene expression in SH-SY5Y cells
inferred← citeshttps://doi.org/10.1080/09553002.2024.2435320openalex-snapshot
Autophagy related proteins as potential biomarkers in predicting cancer prognosis after chemoradiotherapy: systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1080/09553002.2026.2730060openalex-snapshot
Ionizing radiation induces bidirectional transcriptomic reprogramming and dynamic NOS2/TREM2 regulation in triple-negative breast cancer cells
inferred← citeshttps://doi.org/10.1080/14728222.2024.2344697openalex-snapshot
Current strategies for targeting HPK1 in cancer and the barriers to preclinical progress
inferred← citeshttps://doi.org/10.1080/14737140.2025.2466680openalex-snapshot
An update understanding of stemness and chemoresistance of prostate cancer
inferred← citeshttps://doi.org/10.1080/1547691x.2023.2175078openalex-snapshot
Silver nanoparticles induce a non-immunogenic tumor cell death
inferred← citeshttps://doi.org/10.1080/22311866.2024.2446936openalex-snapshot
Assessment of Piper nigrum essential oil from Eastern India: Insights into chemical profiling, antimicrobial and antiproliferative potential
inferred← citeshttps://doi.org/10.1093/jmcb/mjac020openalex-snapshot
Deacetylation of MTHFD2 by SIRT4 senses stress signal to inhibit cancer cell growth by remodeling folate metabolism
inferred← citeshttps://doi.org/10.1093/milmed/usaf119openalex-snapshot
Tumor Acidity as a Result of the Warburg Effect in Cancer Glucose Metabolism and Its Role in Cancer Progression—A Review
inferred← citeshttps://doi.org/10.1097/md.0000000000039377openalex-snapshot
Development and application of a serious adverse events risk model for concurrent chemoradiotherapy in patients with nasopharyngeal carcinoma
inferred← citeshttps://doi.org/10.1101/2024.12.20.629740openalex-snapshot
Anti-Cancer Immune Priming with Beta-Radioligand Therapy and Isoform-Selective Targeting of 4Ig-B7-H3
inferred← citeshttps://doi.org/10.1101/2025.07.18.25331799openalex-snapshot
Profiling Neoadjuvant Therapy Response in Rectal Cancer Using Publicly Available Transcriptomic RNA-seq Datasets
inferred← citeshttps://doi.org/10.1109/bdimed67722.2025.11309328openalex-snapshot
Graph Neural Network-Based Modeling Study of the Molecular Mechanisms of Intestinal Metaplasia-to-Gastric Cancer Transformation Under the Action of mRNA Vaccines
inferred← citeshttps://doi.org/10.1109/icecai58670.2023.10176531openalex-snapshot
Regulatory association prediction of microRNA and cancer radiation response based on Bayesian personalized ranking matrix factorization and deep auto-encoder
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