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Targeting Programmed Cell Death Using Small‐Molecule Compounds to Improve Potential Cancer Therapy

https://doi.org/10.1002/med.21398
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Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase
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Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
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Regulation of Ferroptotic Cancer Cell Death by GPX4
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Pseudolaric acid B induces mitotic catastrophe followed by apoptotic cell death in murine fibrosarcoma L929 cells
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Chk1 Instability Is Coupled to Mitotic Cell Death of p53-deficient Cells in Response to Virus-induced DNA Damage Signaling
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Poly(ADP-ribose): PARadigms and PARadoxes
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No Life Without Death
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Withaferin A, a Steroidal Lactone from Withania somnifera, Induces Mitotic Catastrophe and Growth Arrest in Prostate Cancer Cells
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Non-canonical inflammasome activation targets caspase-11
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Small-molecule activation of the TRAIL receptor DR5 in human cancer cells
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Direct and selective small-molecule activation of proapoptotic BAX
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ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets
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Restoration of the tumor suppressor function to mutant p53 by a low-molecular-weight compound
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Caspase-independent cell death
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Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing
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Hypermethylation of the gene promoter and enhancer region can regulate Fas expression and sensitivity in colon carcinoma
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Vitamin D analog EB1089 triggers dramatic lysosomal changes and Beclin 1-mediated autophagic cell death
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Anoikis
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Oxidative stress induces autophagic cell death independent of apoptosis in transformed and cancer cells
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Autophagic programmed cell death by selective catalase degradation
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Poly(ADP-ribose) (PAR) polymer is a death signal
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Multiple BH3 Mimetics Antagonize Antiapoptotic MCL1 Protein by Inducing the Endoplasmic Reticulum Stress Response and Up-regulating BH3-only Protein NOXA
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Cellular, Biochemical, and Genetic Analysis of Mechanism of Small Molecule IAP Inhibitors
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Deficient Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL) Death Receptor Transport to the Cell Surface in Human Colon Cancer Cells Selected for Resistance to TRAIL-induced Apoptosis
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Regulation of Poly(ADP-ribose) Polymerase-1 by DNA Structure-specific Binding
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Disruption of epithelial cell-matrix interactions induces apoptosis
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Novel cell death program leads to neutrophil extracellular traps
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The rebel angel: mutant p53 as the driving oncogene in breast cancer
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Synergistic Targeting of AML Stem/Progenitor Cells With IAP Antagonist Birinapant and Demethylating Agents
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Small molecule induced reactivation of mutant p53 in cancer cells
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PP242 suppresses cell proliferation, metastasis, and angiogenesis of gastric cancer through inhibition of the PI3K/AKT/mTOR pathway
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Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis
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An inhibition of p62/ SQSTM 1 caused autophagic cell death of several human carcinoma cells
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Inhibition of mTOR by temsirolimus contributes to prolonged survival of mice with pleural dissemination of non‐small‐cell lung cancer cells
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Plant natural compounds: targeting pathways of autophagy as anti‐cancer therapeutic agents
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Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
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Fangchinoline induces autophagic cell death via p53/sestrin2/AMPK signalling in human hepatocellular carcinoma cells
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TNF and ubiquitin at the crossroads of gene activation, cell death, inflammation, and cancer
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Learning and Confirming with Preclinical Studies: Modeling and Simulation in the Discovery of GDC-0917, an Inhibitor of Apoptosis Proteins Antagonist
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Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death
inferredcites →https://doi.org/10.1126/science.1071553openalex-snapshot
The Fas Signaling Pathway: More Than a Paradigm
inferredcites →https://doi.org/10.1126/science.1092472openalex-snapshot
In Vivo Activation of the p53 Pathway by Small-Molecule Antagonists of MDM2
inferredcites →https://doi.org/10.1126/science.1172308openalex-snapshot
RIP3, an Energy Metabolism Regulator That Switches TNF-Induced Cell Death from Apoptosis to Necrosis
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Autophagy and Metabolism
inferredcites →https://doi.org/10.1126/science.274.5289.948openalex-snapshot
Structure of the MDM2 Oncoprotein Bound to the p53 Tumor Suppressor Transactivation Domain
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Somatic Frameshift Mutations in the BAX Gene in Colon Cancers of the Microsatellite Mutator Phenotype
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Molecular Cloning of the Chromosomal Breakpoint of B-Cell Lymphomas and Leukemias with the t(11;14) Chromosome Translocation
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Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects
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Regulation Mechanisms and Signaling Pathways of Autophagy
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Collagen Structure and Stability
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Mitochondrial Membrane Permeabilization in Cell Death
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ABT-263: A Potent and Orally Bioavailable Bcl-2 Family Inhibitor
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Sorafenib Enhances Pemetrexed Cytotoxicity through an Autophagy-Dependent Mechanism in Cancer Cells
inferredcites →https://doi.org/10.1158/0008-5472.can-12-2807openalex-snapshot
MDM2 Small-Molecule Antagonist RG7112 Activates p53 Signaling and Regresses Human Tumors in Preclinical Cancer Models
inferredcites →https://doi.org/10.1158/0008-5472.can-14-0799openalex-snapshot
SAR405838: An Optimized Inhibitor of MDM2–p53 Interaction That Induces Complete and Durable Tumor Regression
inferredcites →https://doi.org/10.1158/1078-0432.ccr-06-1574openalex-snapshot
Preclinical Studies of TW-37, a New Nonpeptidic Small-Molecule Inhibitor of Bcl-2, in Diffuse Large Cell Lymphoma Xenograft Model Reveal Drug Action on Both Bcl-2 and Mcl-1
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-2518openalex-snapshot
The Novel SMAC Mimetic Birinapant Exhibits Potent Activity against Human Melanoma Cells
inferredcites →https://doi.org/10.1158/1535-7163.mct-06-0511openalex-snapshot
Shikonin circumvents cancer drug resistance by induction of a necroptotic death
inferredcites →https://doi.org/10.1158/1535-7163.mct-07-2391openalex-snapshot
Breaching the DNA damage checkpoint via PF-00477736, a novel small-molecule inhibitor of checkpoint kinase 1
inferredcites →https://doi.org/10.1158/1535-7163.mct-09-0160openalex-snapshot
NVP-BEZ235, a novel dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor, elicits multifaceted antitumor activities in human gliomas
inferredcites →https://doi.org/10.1158/1535-7163.mct-12-0767openalex-snapshot
A Novel Small-Molecule Inhibitor of Mcl-1 Blocks Pancreatic Cancer Growth In Vitro and In Vivo
inferredcites →https://doi.org/10.1158/1535-7163.mct-13-0798openalex-snapshot
Birinapant (TL32711), a Bivalent SMAC Mimetic, Targets TRAF2-Associated cIAPs, Abrogates TNF-Induced NF-κB Activation, and Is Active in Patient-Derived Xenograft Models
inferredcites →https://doi.org/10.1158/1541-7786.mcr-14-0440openalex-snapshot
High-Throughput Drug Screen Identifies Chelerythrine as a Selective Inducer of Death in a TSC2-null Setting
inferredcites →https://doi.org/10.1158/1940-6207.capr-13-0259openalex-snapshot
Curcumin: A Double Hit on Malignant Mesothelioma
inferredcites →https://doi.org/10.1172/jci34120openalex-snapshot
Resistance of human glioblastoma multiforme cells to growth factor inhibitors is overcome by blockade of inhibitor of apoptosis proteins
inferredcites →https://doi.org/10.1182/blood-2010-02-268003openalex-snapshot
Reversion of epigenetically mediated BIM silencing overcomes chemoresistance in Burkitt lymphoma
inferredcites →https://doi.org/10.1186/bcr3604openalex-snapshot
Impact of dual mTORC1/2 mTOR kinase inhibitor AZD8055 on acquired endocrine resistance in breast cancer in vitro
inferredcites →https://doi.org/10.1186/s12943-015-0397-yopenalex-snapshot
Genomic analysis and selective small molecule inhibition identifies BCL-XL as a critical survival factor in a subset of colorectal cancer
inferredcites →https://doi.org/10.1242/jcs.146373openalex-snapshot
Torin1 mediated TOR kinase inhibition reduces Wee1 levels and advances mitotic commitment in fission yeast and HeLa cells
inferredcites →https://doi.org/10.1371/journal.pone.0007124openalex-snapshot
Screen for Chemical Modulators of Autophagy Reveals Novel Therapeutic Inhibitors of mTORC1 Signaling
inferredcites →https://doi.org/10.1371/journal.pone.0092546openalex-snapshot
Multi-Kinase Inhibitor C1 Triggers Mitotic Catastrophe of Glioma Stem Cells Mainly through MELK Kinase Inhibition
inferredcites →https://doi.org/10.18632/oncotarget.2528openalex-snapshot
The induction of the p53 tumor suppressor protein bridges the apoptotic and autophagic signaling pathways to regulate cell death in prostate cancer cells
inferredcites →https://doi.org/10.18632/oncotarget.2529openalex-snapshot
Preclinical efficacy of sepantronium bromide (YM155) in multiple myeloma is conferred by down regulation of Mcl-1
inferredcites →https://doi.org/10.18632/oncotarget.2642openalex-snapshot
Preclinical efficacy of maternal embryonic leucine-zipper kinase (MELK) inhibition in acute myeloid leukemia
inferredcites →https://doi.org/10.18632/oncotarget.3038openalex-snapshot
Neoalbaconol induces cell death through necroptosis by regulating RIPK-dependent autocrine TNFα and ROS production
inferredcites →https://doi.org/10.18632/oncotarget.3105openalex-snapshot
Computational design, chemical synthesis, and biological evaluation of a novel ERK inhibitor (BL-EI001) with apoptosis-inducing mechanisms in breast cancer
inferredcites →https://doi.org/10.18632/oncotarget.3513openalex-snapshot
Systems biology network-based discovery of a small molecule activator BL-AD008 targeting AMPK/ZIPK and inducing apoptosis in cervical cancer
inferredcites →https://doi.org/10.18632/oncotarget.4315openalex-snapshot
YM155, a survivin suppressant, triggers PARP-dependent cell death (parthanatos) and inhibits esophageal squamous-cell carcinoma xenografts in mice
inferredcites →https://doi.org/10.2174/1568009043332763openalex-snapshot
Targeting Apoptosis Pathways in Cancer Therapy
inferredcites →https://doi.org/10.2217/fon.14.303openalex-snapshot
Future perspectives for mTOR inhibitors in renal cell cancer treatment
inferredcites →https://doi.org/10.3109/10428199809092690openalex-snapshot
Elevated Bcl-2/Bax Are a Consistent Feature of Apoptosis Resistance in B-cell Chronic Lymphocytic Leukaemia and Are Correlated withIn VivoChemoresistance
inferredcites →https://doi.org/10.3892/or.2014.3190openalex-snapshot
Mechanisms associated with resistance to tamoxifen in estrogen receptor-positive breast cancer (Review)
inferredcites →https://doi.org/10.4161/auto.23323openalex-snapshot
The ULK1 complex
inferredcites →https://doi.org/10.4161/auto.28034openalex-snapshot
The natural compound oblongifolin C inhibits autophagic flux and enhances antitumor efficacy of nutrient deprivation
inferredcites →https://doi.org/10.4161/auto.5778openalex-snapshot
Apoptosis meets autophagy-like cell death in the ischemic penumbra: Two sides of the same coin?
inferredcites →https://doi.org/10.4161/cbt.26428openalex-snapshot
The mechanism of necroptosis in normal and cancer cells
inferredcites →https://doi.org/10.5732/cjc.012.10010openalex-snapshot
Targeting autophagic pathways for cancer drug discovery

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4765237openalex-extracted
New Synergistic Benzoquinone Scaffolds as Inhibitors of Mycobacterial Cytochrome Bc1 Complex to Treat Multi-Drug Resistant Tuberculosis
inferred← citeshttps://doi.org/10.1002/adhm.202402697openalex-snapshot
Recent Advances in Nanomaterial‐Mediated Cell Death for Cancer Therapy
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Asymmetric Construction of Spiropyrazolone Skeletons via Amine‐Catalyzed [3+3] Annulation
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Cellular metabolism: A key player in cancer ferroptosis
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Development of venetoclax performance using its new derivatives on BCL‐2 protein inhibition
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Chemo‐ and Stereoselective Cross Rauhut–Currier‐Type Reaction of Tri‐substituted Alkenes Containing Trifluoromethyl Groups
inferred← citeshttps://doi.org/10.1002/cmdc.202000722openalex-snapshot
Design and Efficient Synthesis of RalA Inhibitors Containing the Dihydro‐α‐carboline Scaffold
inferred← citeshttps://doi.org/10.1002/cmdc.202200104openalex-snapshot
Design, Synthesis, and Biological Evaluation of Tetrahydro‐α‐carbolines as Akt1 Inhibitors That Inhibit Colorectal Cancer Cell Proliferation
inferred← citeshttps://doi.org/10.1002/jcla.24465openalex-snapshot
Ferroptosis‐based molecular prognostic model for adrenocortical carcinoma based on least absolute shrinkage and selection operator regression
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Cell death pathways: molecular mechanisms and therapeutic targets for cancer
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Ferroptosis‐modulating small molecules for targeting drug‐resistant cancer: Challenges and opportunities in manipulating redox signaling
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Drugging ERK1/2 in Cancer: A Glimpse of Small‐Molecule Inhibitors
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Catalytic Asymmetric Synthesis of Spiropyrazolones and their Application in Medicinal Chemistry
inferred← citeshttps://doi.org/10.1007/978-3-319-98146-8_1openalex-snapshot
Autophagy and Stem Cells
inferred← citeshttps://doi.org/10.1007/s00018-018-2759-2openalex-snapshot
Mechanisms of autophagy and relevant small-molecule compounds for targeted cancer therapy
inferred← citeshttps://doi.org/10.1007/s11010-020-03699-6openalex-snapshot
Arctigenin induces necroptosis through mitochondrial dysfunction with CCN1 upregulation in prostate cancer cells under lactic acidosis
inferred← citeshttps://doi.org/10.1007/s11010-022-04644-5openalex-snapshot
Ferroptosis: mechanisms and advances in ocular diseases
inferred← citeshttps://doi.org/10.1007/s11030-019-10011-2openalex-snapshot
Design and synthesis of novel spirooxindole–indenoquinoxaline derivatives as novel tryptophanyl-tRNA synthetase inhibitors
inferred← citeshttps://doi.org/10.1007/s12032-024-02317-5openalex-snapshot
Ferroptosis is an effective strategy for cancer therapy
inferred← citeshttps://doi.org/10.1007/s12094-024-03784-yopenalex-snapshot
Targeting mitochondria and programmed cell death as potential interventions for metastatic castration-resistant prostate cancer
inferred← citeshttps://doi.org/10.1007/s12672-025-03257-wopenalex-snapshot
Leveraging diverse cell-death patterns to predict to predict prognosis and immunotherapy in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1007/s40610-021-00146-3openalex-snapshot
Cell Death: a Molecular Perspective
inferred← citeshttps://doi.org/10.1016/b978-0-12-823397-9.00001-6openalex-snapshot
The hallmarks of cancer and immunology
inferred← citeshttps://doi.org/10.1016/j.actbio.2018.05.030openalex-snapshot
Lipid-modified cell-penetrating peptide-based self-assembly micelles for co-delivery of narciclasine and siULK1 in hepatocellular carcinoma therapy
inferred← citeshttps://doi.org/10.1016/j.apsb.2019.02.002openalex-snapshot
Updated developments on molecular imaging and therapeutic strategies directed against necrosis
inferred← citeshttps://doi.org/10.1016/j.apsb.2019.12.013openalex-snapshot
Rational drug design, synthesis, and biological evaluation of novel chiral tetrahydronaphthalene-fused spirooxindole as MDM2-CDK4 dual inhibitor against glioblastoma
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.05.032openalex-snapshot
MCDB: A comprehensive curated mitotic catastrophe database for retrieval, protein sequence alignment, and target prediction
inferred← citeshttps://doi.org/10.1016/j.arabjc.2017.09.015openalex-snapshot
Synthesis, physicochemical elucidation, biological screening and molecular docking studies of a Schiff base and its metal(II) complexes
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.05.025openalex-snapshot
Proteolytic control of regulated necrosis
inferred← citeshttps://doi.org/10.1016/j.bcp.2017.07.018openalex-snapshot
Downregulation of TIGAR sensitizes the antitumor effect of physapubenolide through increasing intracellular ROS levels to trigger apoptosis and autophagosome formation in human breast carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.117418openalex-snapshot
Bromodomain containing protein 4 (BRD4) and cancer therapy: A glimpse at dual-target drug development
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.117692openalex-snapshot
Modulating UNC-51-like kinase 1 (ULK1) to treat diseases: A perspective from autophagic initiator to druggable target
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2016.12.032openalex-snapshot
Killing colon cancer cells through PCD pathways by a novel hyaluronic acid-modified shell-core nanoparticle loaded with RIP3 in combination with chloroquine
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106930openalex-snapshot
Green synthesis and anti-tumor efficacy via inducing pyroptosis of novel 1H-benzo[e]indole-2(3H)-one spirocyclic derivatives
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.05.017openalex-snapshot
Hispidulin alleviates high-glucose-induced podocyte injury by regulating protective autophagy
inferred← citeshttps://doi.org/10.1016/j.biopha.2018.07.132openalex-snapshot
Inhibition of EP300 and DDR1 synergistically alleviates pulmonary fibrosis in vitro and in vivo
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.108775openalex-snapshot
Insights into autophagy machinery in cells related to skin diseases and strategies for therapeutic modulation
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109203openalex-snapshot
Small-molecule compounds target paraptosis to improve cancer therapy
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113511openalex-snapshot
Nanosilver inhibits the progression of pancreatic cancer by inducing a paraptosis-like mixed type of cell death
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115892openalex-snapshot
The mitochondrial regulation in ferroptosis signaling pathway and its potential strategies for cancer
inferred← citeshttps://doi.org/10.1016/j.bmc.2019.04.022openalex-snapshot
Design, synthesis and biological evaluation of 4-aniline-thieno[2,3-d]pyrimidine derivatives as MNK1 inhibitors against renal cell carcinoma and nasopharyngeal carcinoma
inferred← citeshttps://doi.org/10.1016/j.cclet.2021.01.033openalex-snapshot
Discovery of spirooxindole–ferrocene hybrids as novel MDM2 inhibitors
inferred← citeshttps://doi.org/10.1016/j.compbiomed.2022.105789openalex-snapshot
In vitro characterization and molecular dynamic simulation of shikonin as a tubulin-targeted anticancer agent
inferred← citeshttps://doi.org/10.1016/j.drudis.2020.07.021openalex-snapshot
Myeloid cell leukemin-1 inhibitors: a growing arsenal for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.drudis.2022.05.011openalex-snapshot
Targeting autophagy in colorectal cancer: An update on pharmacological small-molecule compounds
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.12.046openalex-snapshot
Design, synthesis, and biological evaluation of polo-like kinase 1/eukaryotic elongation factor 2 kinase (PLK1/EEF2K) dual inhibitors for regulating breast cancer cells apoptosis and autophagy
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112076openalex-snapshot
Discovery of novel akt1 inhibitor induces autophagy associated death in hepatocellular carcinoma cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112314openalex-snapshot
Discovery of novel TNNI3K inhibitor suppresses pyroptosis and apoptosis in murine myocardial infarction injury
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.112661openalex-snapshot
Synthesis and in vitro anti-bladder cancer activity evaluation of quinazolinyl-arylurea derivatives
inferred← citeshttps://doi.org/10.1016/j.ejmech.2020.113088openalex-snapshot
Discovery of a novel small-molecule inhibitor of Fam20C that induces apoptosis and inhibits migration in triple negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113359openalex-snapshot
Design, synthesis, and biological evaluation of nitroisoxazole-containing spiro[pyrrolidin-oxindole] derivatives as novel glutathione peroxidase 4/mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114674openalex-snapshot
Design, synthesis, and biological evaluation of novel dual inhibitors of heat shock protein 90/mammalian target of rapamycin (Hsp90/mTOR) against bladder cancer cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.115009openalex-snapshot
Discovery of tetrahydrofuranyl spirooxindole-based SMYD3 inhibitors against gastric cancer via inducing lethal autophagy
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116479openalex-snapshot
New synergistic benzoquinone scaffolds as inhibitors of mycobacterial cytochrome bc1 complex to treat multi-drug resistant tuberculosis
inferred← citeshttps://doi.org/10.1016/j.envres.2023.116526openalex-snapshot
Nanoarchitecture-based photothermal ablation of cancer: A systematic review
inferred← citeshttps://doi.org/10.1016/j.fct.2019.04.012openalex-snapshot
Natural products: An upcoming therapeutic approach to cancer
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.148014openalex-snapshot
Unravelling the oncogenic role of eukaryotic elongation factor 2 kinase: A revisited review from underlying mechanisms to targeted therapy
inferred← citeshttps://doi.org/10.1016/j.jdermsci.2021.02.005openalex-snapshot
Long non-coding RNA NEAT1 functions as a competing endogenous RNA to regulate S100A9 expression by sponging miR-196a-5p in rosacea
inferred← citeshttps://doi.org/10.1016/j.medidd.2026.100264openalex-snapshot
Phenanthrene and dihydrophenanthrene derivatives from Vanda curvifolia with cytotoxic activity against glioblastoma cells
inferred← citeshttps://doi.org/10.1016/j.molstruc.2026.145334openalex-snapshot
Recent advances in construction of spiropyrazolones from the ɑ,β-unsaturated pyrazolones
inferred← citeshttps://doi.org/10.1016/j.mtadv.2026.100693openalex-snapshot
Advance of different strategies to achieve radiosensitivity based on nanomaterials
inferred← citeshttps://doi.org/10.1016/j.oor.2023.100040openalex-snapshot
Cancer treatment: Role of natural products. Time to have a serious rethink
inferred← citeshttps://doi.org/10.1016/j.placenta.2018.08.006openalex-snapshot
Associations between fetal size, sex and both proliferation and apoptosis at the porcine feto-maternal interface
inferred← citeshttps://doi.org/10.1016/j.prp.2021.153645openalex-snapshot
The role of long noncoding RNAs in patients with Luminal A invasive breast ductal carcinoma
inferred← citeshttps://doi.org/10.1016/j.tet.2023.133580openalex-snapshot
Efficient enantioselective synthesis of CF2H-containing dispiro [benzo[b]thiophene-pyrrolidine-pyrazole]s via organocatalytic cycloaddition
inferred← citeshttps://doi.org/10.1016/j.tetlet.2025.155921openalex-snapshot
Urea-promoted simple and efficient synthesis of diverse and densely functionalized 4,4′-(arylmethylene)bis(1H-pyrazol-5-ols) in aqueous ethanol
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.0c00119openalex-snapshot
Imaging Cell Death: Focus on Early Evaluation of Tumor Response to Therapy
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01180openalex-snapshot
Small-Molecule Drug Discovery in Triple Negative Breast Cancer: Current Situation and Future Directions
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.7b00275openalex-snapshot
Discovery of a Small-Molecule Bromodomain-Containing Protein 4 (BRD4) Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.9b02178openalex-snapshot
Discovery of Thieno[2,3-d]pyrimidine-Based Hydroxamic Acid Derivatives as Bromodomain-Containing Protein 4/Histone Deacetylase Dual Inhibitors Induce Autophagic Cell Death in Colorectal Carcinoma Cells
inferred← citeshttps://doi.org/10.1021/acs.joc.8b02188openalex-snapshot
Lewis-Base-Catalyzed [1 + 2 + 2] Annulation Reaction of Morita–Baylis–Hillman Carbonates with Unsaturated Pyrazolones: Construction of All-Stereogenic Carbon Cyclopentane-Fused Dispiropyrazolones
inferred← citeshttps://doi.org/10.1021/acs.joc.9b01098openalex-snapshot
Stereoselective Assembly of Multifunctional Spirocyclohexene Pyrazolones That Induce Autophagy-Dependent Apoptosis in Colorectal Cancer Cells
inferred← citeshttps://doi.org/10.1021/acs.joc.9b02029openalex-snapshot
Regioselective N-Addition/Substitution Reaction of α-Alkylidene Pyrazolinones with Propargyl Sulfonium Salts to Construct Allylthio-Containing Pyrazolones
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.8b00996openalex-snapshot
In Silico Discovery of a Small Molecule Suppressing Lung Carcinoma A549 Cells Proliferation and Inducing Autophagy via mTOR Pathway Inhibition
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c02836openalex-snapshot
Unconventional [2 + 3] Cyclization Involving [1,4]-Sulfonyl Transfer to Construct Polysubstituted Fluorazones as Inhibitors of Indoleamine 2,3-Dioxygenase 1
inferred← citeshttps://doi.org/10.1021/acs.orglett.7b03516openalex-snapshot
Organocatalytic Asymmetric Synthesis of Spiro-oxindole Piperidine Derivatives That Reduce Cancer Cell Proliferation by Inhibiting MDM2–p53 Interaction
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b00168openalex-snapshot
Enantioselective Vinylogous Michael–Aldol Reaction To Synthesize Spirocyclohexene Pyrazolones in Aqueous Media
inferred← citeshttps://doi.org/10.1021/acs.orglett.9b02927openalex-snapshot
NHC-Catalyzed Asymmetric Formal [4 + 2] Annulation To Construct Spirocyclohexane Pyrazolone Skeletons
inferred← citeshttps://doi.org/10.1021/acsanm.5c03823openalex-snapshot
Hydroxyl Radical-Responsive Nanoprobe Enables Ratiometric Fluorescence Monitoring of Cancer Cell Treatment Response
inferred← citeshttps://doi.org/10.1021/acsomega.2c04506openalex-snapshot
Visible Light-Promoted Green and Sustainable Approach for One-Pot Synthesis of 4,4’-(Arylmethylene)bis(1H-pyrazol-5-ols), In Vitro Anticancer Activity, and Molecular Docking with Covid-19 Mpro
inferred← citeshttps://doi.org/10.1021/jacsau.3c00228openalex-snapshot
Targeting GDP-Dissociation Inhibitor Beta (GDI2) with a Benzo[a]quinolizidine Library to Induce Paraptosis for Cancer Therapy
inferred← citeshttps://doi.org/10.1038/s41392-020-00428-9openalex-snapshot
Ferroptosis: mechanisms and links with diseases
inferred← citeshttps://doi.org/10.1038/s41419-018-0799-zopenalex-snapshot
A novel small-molecule activator of Sirtuin-1 induces autophagic cell death/mitophagy as a potential therapeutic strategy in glioblastoma
inferred← citeshttps://doi.org/10.1038/s41419-018-1261-yopenalex-snapshot
Sanshool improves UVB-induced skin photodamage by targeting JAK2/STAT3-dependent autophagy
inferred← citeshttps://doi.org/10.1038/s41419-022-04943-1openalex-snapshot
Oncogenic circTICRR suppresses autophagy via binding to HuR protein and stabilizing GLUD1 mRNA in cervical cancer
inferred← citeshttps://doi.org/10.1038/s41419-023-06370-2openalex-snapshot
Mechanisms of PANoptosis and relevant small-molecule compounds for fighting diseases
inferred← citeshttps://doi.org/10.1038/s41433-024-03371-zopenalex-snapshot
Ferroptosis in eye diseases: a systematic review
inferred← citeshttps://doi.org/10.1038/s41598-022-24879-yopenalex-snapshot
The expression pattern of pyroptosis-related genes predicts the prognosis and drug response of melanoma
inferred← citeshttps://doi.org/10.1039/c6mb00653aopenalex-snapshot
Integrating multiple omics data for the discovery of potential Beclin-1 interactions in breast cancer
inferred← citeshttps://doi.org/10.1039/c6sc05368hopenalex-snapshot
Discovery of a small molecule targeting ULK1-modulated cell death of triple negative breast cancer in vitro and in vivo
inferred← citeshttps://doi.org/10.1039/c8cc04732dopenalex-snapshot
Asymmetric synthesis of tetrahydroisoquinoline-fused spirooxindoles as Ras-GTP inhibitors that inhibit colon adenocarcinoma cell proliferation and invasion
inferred← citeshttps://doi.org/10.1039/c8ra06548aopenalex-snapshot
Synthesis, antitumor activity and molecular mechanism of doxorubicin conjugated trimethyl-chitosan polymeric micelle loading Beclin1 siRNA for drug-resisted bladder cancer therapy
inferred← citeshttps://doi.org/10.1039/c9cc05916dopenalex-snapshot
Organocatalytic diastereoselective [3+2] cyclization of MBH carbonates with dinucleophiles: synthesis of bicyclic imidazoline derivatives that inhibit MDM2–p53 interaction
inferred← citeshttps://doi.org/10.1039/c9fo00063aopenalex-snapshot
Isodunnianol alleviates doxorubicin-induced myocardial injury by activating protective autophagy
inferred← citeshttps://doi.org/10.1039/c9ra07610gopenalex-snapshot
Combined inorganic base promoted N-addition/[2,3]-sigmatropic rearrangement to construct homoallyl sulfur-containing pyrazolones
inferred← citeshttps://doi.org/10.1039/d0ob00482kopenalex-snapshot
A Rh-catalyzed three-component reaction for the diastereoselective synthesis of pyrazolone derivatives with contiguous quaternary stereocenters
inferred← citeshttps://doi.org/10.1039/d1nj00619copenalex-snapshot
Supramolecular assemblies involving biologically relevant antiparallel π-stacking and unconventional solvent driven structural topology in maleato and fumarato bridged Zn( ii ) coordination polymers: antiproliferative evaluation and theoretical studies
inferred← citeshttps://doi.org/10.1055/a-1771-0641openalex-snapshot
Stereoselective Domino Reactions in the Synthesis of Spiro Compounds
inferred← citeshttps://doi.org/10.1063/5.0253463openalex-snapshot
Quercetin targets the Ccl4–Ccr5 axis to relieve neuropathic pain after spinal cord injury
inferred← citeshttps://doi.org/10.1080/0886022x.2021.1936040openalex-snapshot
ATF4-dependent heme-oxygenase-1 attenuates diabetic nephropathy by inducing autophagy and inhibiting apoptosis in podocyte
inferred← citeshttps://doi.org/10.1080/14756366.2019.1596903openalex-snapshot
Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma
inferred← citeshttps://doi.org/10.1080/21655979.2021.1921552openalex-snapshot
Relationship between hepatocellular carcinoma and depression via online database analysis
inferred← citeshttps://doi.org/10.1089/jmf.2021.k.0059openalex-snapshot
Ginkgolic Acid Suppresses Nasopharyngeal Carcinoma Growth by Inducing Apoptosis and Inhibiting AKT/NF-κB Signaling
inferred← citeshttps://doi.org/10.1111/cpr.12403openalex-snapshot
Autophagic compound database: A resource connecting autophagy‐modulating compounds, their potential targets and relevant diseases
inferred← citeshttps://doi.org/10.1111/cpr.12701openalex-snapshot
Aconitine induces cardiomyocyte damage by mitigating BNIP3‐dependent mitophagy and the TNFα‐NLRP3 signalling axis
inferred← citeshttps://doi.org/10.1111/exd.13934openalex-snapshot
Salicylic acid treats acne vulgaris by suppressing AMPK / SREBP 1 pathway in sebocytes
inferred← citeshttps://doi.org/10.1111/jcmm.17001openalex-snapshot
Fusion of apoptosis‐related protein Cytochrome c with anti‐HER‐2 single‐chain antibody targets the suppression of HER‐2+ breast cancer
inferred← citeshttps://doi.org/10.1111/pcmr.13185openalex-snapshot
The prognostic implications of cuproptosis‐related gene signature and the potential of PPIC as a promising biomarker in cutaneous melanoma
inferred← citeshttps://doi.org/10.1111/pin.12507openalex-snapshot
Bcl‐2 family in non‐small cell lung cancer: its prognostic and therapeutic implications
inferred← citeshttps://doi.org/10.1152/ajpgi.00354.2021openalex-snapshot
MCTR1 inhibits ferroptosis by promoting NRF2 expression to attenuate hepatic ischemia-reperfusion injury
inferred← citeshttps://doi.org/10.1155/2018/3074769openalex-snapshot
Yeast Cells Exposed to Exogenous Palmitoleic Acid Either Adapt to Stress and Survive or Commit to Regulated Liponecrosis and Die
inferred← citeshttps://doi.org/10.1155/2020/9705950openalex-snapshot
Identification of Long Noncoding RNA Associated ceRNA Networks in Rosacea
inferred← citeshttps://doi.org/10.1155/2021/1587922openalex-snapshot
Targeting Ferroptosis: Pathological Mechanism and Treatment of Ischemia‐Reperfusion Injury
inferred← citeshttps://doi.org/10.1155/2021/7169211openalex-snapshot
Identifying Active Compounds and Mechanism of Camellia nitidissima Chi on Anti-Colon Cancer by Network Pharmacology and Experimental Validation
inferred← citeshttps://doi.org/10.1155/2021/8859181openalex-snapshot
Curcumin Targets Both Apoptosis and Necroptosis in Acidity‐Tolerant Prostate Carcinoma Cells
inferred← citeshttps://doi.org/10.1155/2022/2721005openalex-snapshot
Deciphering a Novel Necroptosis-Related miRNA Signature for Predicting the Prognosis of Clear Cell Renal Carcinoma
inferred← citeshttps://doi.org/10.1155/2022/6609297openalex-snapshot
Pan-Cancer Pyroptosis Analyses Identified Novel Immunology and Chemotherapy-Related Prognostic Signatures in Cancer Subtypes
inferred← citeshttps://doi.org/10.1172/jci.insight.136720openalex-snapshot
Interferon regulatory factor 1 regulates PANoptosis to prevent colorectal cancer
inferred← citeshttps://doi.org/10.1186/s12935-023-02960-4openalex-snapshot
Flavonoids target different molecules of autophagic and metastatic pathways in cancer cells
inferred← citeshttps://doi.org/10.1186/s12967-022-03641-yopenalex-snapshot
CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.1186/s13045-022-01260-0openalex-snapshot
Targeting regulated cell death (RCD) with small-molecule compounds in triple-negative breast cancer: a revisited perspective from molecular mechanisms to targeted therapies
inferred← citeshttps://doi.org/10.1186/s13062-025-00624-zopenalex-snapshot
L-741626 inhibits hepatocellular carcinoma progression by targeting Ref-1 to suppress MAPK/ERK signalling pathway activity
inferred← citeshttps://doi.org/10.1186/s13071-022-05291-xopenalex-snapshot
Plasmodium infection suppresses colon cancer growth by inhibiting proliferation and promoting apoptosis associated with disrupting mitochondrial biogenesis and mitophagy in mice
inferred← citeshttps://doi.org/10.18632/aging.102483openalex-snapshot
Competing endogenous network analysis identifies lncRNA Meg3 activates inflammatory damage in UVB induced murine skin lesion by sponging miR-93-5p/epiregulin axis
inferred← citeshttps://doi.org/10.18632/oncotarget.19299openalex-snapshot
Anti-proliferation of triple-negative breast cancer cells with physagulide P: ROS/JNK signaling pathway induces apoptosis and autophagic cell death
inferred← citeshttps://doi.org/10.18632/oncotarget.19596openalex-snapshot
Long non-coding RNA NEAT1 regulates epithelial membrane protein 2 expression to repress nasopharyngeal carcinoma migration and irradiation-resistance through miR-101-3p as a competing endogenous RNA mechanism
inferred← citeshttps://doi.org/10.18632/oncotarget.19950openalex-snapshot
Interleukin-13 peptide vaccine induces protective humoral immunity in murine asthma models
inferred← citeshttps://doi.org/10.20902/ijctr.2019.120136openalex-snapshot
Molecular Docking Studies of Derivatives of Majorana hortensis Leaves against Anti Apoptotic Targets
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2054880/v1openalex-snapshot
The Expression Pattern of Pyroptosis-Related Genes Predicts the Prognosis and Drug Response of Skin Cutaneous Melanoma
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3193390/v1openalex-snapshot
Identification of a cuproptosis-associated gene signature and Peptidylprolyl isomerase C as therapeutic target in cutaneous melanoma
inferred← citeshttps://doi.org/10.2147/ijn.s174349openalex-snapshot
Photothermal exposure of polydopamine-coated branched Au–Ag nanoparticles induces cell cycle arrest, apoptosis, and autophagy in human bladder cancer cells
inferred← citeshttps://doi.org/10.2147/jir.s545938openalex-snapshot
Programmed Cell Death in Diabetic Kidney Disease: Mechanisms and Therapeutic Targeting
inferred← citeshttps://doi.org/10.2174/187152062213220601100200openalex-snapshot
Meet the Editorial Board Member
inferred← citeshttps://doi.org/10.2174/1871520622666220623103957openalex-snapshot
Design, Synthesis and Biological Evaluation of Novel Quinoline Derivatives as Potential Anti-Proliferative Agents Against PC-3 and KG-1 Cells
inferred← citeshttps://doi.org/10.22514/ejgo.2023.060openalex-snapshot
Transcriptome analysis constructed the necroptosis associated prognostic signature in endometrial cancer and identified EZH2 as a potential biomarker
inferred← citeshttps://doi.org/10.23873/2074-0506-2024-16-2-244-259openalex-snapshot
Understudied targets of the ischemia-reperfusion injury pathogenesis in liver transplantation
inferred← citeshttps://doi.org/10.24272/j.issn.2095-8137.2020.042openalex-snapshot
The pathological role of ferroptosis in ischemia/reperfusion-related injury
inferred← citeshttps://doi.org/10.31083/j.rcm2510366openalex-snapshot
Regulated Cell Death Pathways in Pathological Cardiac Hypertrophy
inferred← citeshttps://doi.org/10.31579/2578-8965/227openalex-snapshot
Activating Transcription Factor 5; A Potential Prognostic Molecular Biomarker for Cervical Cancer (CC)
inferred← citeshttps://doi.org/10.3389/fcell.2021.743910openalex-snapshot
Development of an Autophagy-Based and Stemness-Correlated Prognostic Model for Hepatocellular Carcinoma Using Bulk and Single-Cell RNA-Sequencing
inferred← citeshttps://doi.org/10.3389/fendo.2023.1155296openalex-snapshot
Research progress on the mechanism of ferroptosis and its role in diabetic retinopathy
inferred← citeshttps://doi.org/10.3389/fgene.2025.1457204openalex-snapshot
Prognosis of cholangiocarcinoma patients based on multiple patterns of programmed cell death, integrated analysis of the immune microenvironment and drug sensitivity
inferred← citeshttps://doi.org/10.3389/fimmu.2024.1412277openalex-snapshot
A disulfidptosis-related lncRNA signature for analyzing tumor microenvironment and clinical prognosis in hepatocellular carcinoma
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1544693openalex-snapshot
Immunomodulatory effects of photothermal therapy in breast cancer: advances and challenges
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1658769openalex-snapshot
O-GlcNAcylation-regulated classical programmed cell death in diseases: molecular crosstalk and therapeutic opportunities
inferred← citeshttps://doi.org/10.3389/fnut.2022.844757openalex-snapshot
Molecular Mechanisms of Iron Mediated Programmed Cell Death and Its Roles in Eye Diseases
inferred← citeshttps://doi.org/10.3389/fphar.2019.00746openalex-snapshot
Anti-Cancer Effects of Pristimerin and the Mechanisms: A Critical Review
inferred← citeshttps://doi.org/10.3389/fphys.2024.1290234openalex-snapshot
Mechanistic elucidation of ferroptosis and ferritinophagy: implications for advancing our understanding of arthritis
inferred← citeshttps://doi.org/10.3390/biology11111581openalex-snapshot
SMAC Mimetic BV6 Co-Treatment Downregulates the Factors Involved in Resistance and Relapse of Cancer: IAPs and Autophagy
inferred← citeshttps://doi.org/10.3390/biomimetics3020013openalex-snapshot
Oil-In-Water Microemulsions as Hosts for Benzothiophene-Based Cytotoxic Compounds: An Effective Combination
inferred← citeshttps://doi.org/10.3390/biophysica3030028openalex-snapshot
Screening for Bioactive Metabolites in Leaves, Branches, and Roots of Mansoa hirsuta: Phytochemical, Toxicological and Antioxidant Aspects
inferred← citeshttps://doi.org/10.3390/cells11132018openalex-snapshot
iPCD: A Comprehensive Data Resource of Regulatory Proteins in Programmed Cell Death
inferred← citeshttps://doi.org/10.3390/cells13020156openalex-snapshot
The Protective Effect of a Human Umbilical Cord Mesenchymal Stem Cell Supernatant on UVB-Induced Skin Photodamage
inferred← citeshttps://doi.org/10.3390/cells9041012openalex-snapshot
Potency and Selectivity of SMAC/DIABLO Mimetics in Solid Tumor Therapy
inferred← citeshttps://doi.org/10.3390/ijms21051845openalex-snapshot
Novel HSP90-PI3K Dual Inhibitor Suppresses Melanoma Cell Proliferation by Interfering with HSP90-EGFR Interaction and Downstream Signaling Pathways
inferred← citeshttps://doi.org/10.3390/ijms222212302openalex-snapshot
ATG 4B Serves a Crucial Role in RCE-4-Induced Inhibition of the Bcl-2–Beclin 1 Complex in Cervical Cancer Ca Ski Cells
inferred← citeshttps://doi.org/10.3390/molecules27082431openalex-snapshot
Nigrosporins B, a Potential Anti-Cervical Cancer Agent, Induces Apoptosis and Protective Autophagy in Human Cervical Cancer Ca Ski Cells Mediated by PI3K/AKT/mTOR Signaling Pathway
inferred← citeshttps://doi.org/10.3390/ph15121565openalex-snapshot
Non-Apoptotic Programmed Cell Death in Thyroid Diseases
inferred← citeshttps://doi.org/10.3390/ph17050578openalex-snapshot
Anticancer Potential and Molecular Targets of Pristimerin in Human Malignancies
inferred← citeshttps://doi.org/10.3390/ph18111691openalex-snapshot
From Single-Cell and Bulk Transcriptomic Integration to Functional Verification: Triaptosis-Associated lncRNA Signature Predicts Survival and Guides Therapy in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.3390/ph19040535openalex-snapshot
Killing Glioblastoma Cells with Glycosylated Indolocarbazole-Based Derivative LCS1269: A Potential Crosstalk Between Micronuclei Formation and the Concurrent Induction of Apoptosis, Necroptosis, and Pyroptosis
inferred← citeshttps://doi.org/10.3892/ijo.2023.5490openalex-snapshot
High‑throughput screening identification of a small‑molecule compound that induces ferroptosis and attenuates the invasion and migration of hepatocellular carcinoma cells by targeting the STAT3/GPX4 axis
inferred← citeshttps://doi.org/10.3892/or.2020.7566openalex-snapshot
Costunolide induces apoptosis and inhibits migration and invasion in H1299 lung cancer cells
inferred← citeshttps://doi.org/10.3969/j.issn.1673-4254.2017.06.20openalex-snapshot
[Mechanism of Platycarya strobilacea Sieb. et Zucc extract-induced methuosis in human nasopharyngeal carcinoma CNE1 and CNE2 cells].
inferred← citeshttps://doi.org/10.4103/jcrt.jcrt_614_21openalex-snapshot
The role of pyroptosis in lung cancer and compounds regulated pyroptosis of lung cancer cells
inferred← citeshttps://doi.org/10.4172/2169-0138.1000155openalex-snapshot
Molecular Docking Studies of Hydrazide-Hydrazone Derivatives of Gossypol against Bcl-2 Family Anti-Apoptotic Targets
inferred← citeshttps://doi.org/10.5505/ejm.2021.64935openalex-snapshot
Real-Time Detection of Doxorubicin-Induced Apoptosis in Breast Cancer Cells Using the Back Reflection Spectroscopy
inferred← citeshttps://doi.org/10.5505/turkhijyen.2021.54533openalex-snapshot
TBHEB 2021-3 Vol 78 Full Printed Journal
inferred← citeshttps://doi.org/10.5505/turkhijyen.2021.63496openalex-snapshot
Determination of Early Spectral Changes in Melanoma Cells During Epoxomicin-Induced Apoptotic Process
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261617openalex-snapshot
Additional file 1 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261620openalex-snapshot
Additional file 2 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261623openalex-snapshot
Additional file 3 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261626openalex-snapshot
Additional file 4 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261629openalex-snapshot
Additional file 5 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261632openalex-snapshot
Additional file 6 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261635openalex-snapshot
Additional file 7 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.6084/m9.figshare.21261638openalex-snapshot
Additional file 8 of CDK1 serves as a therapeutic target of adrenocortical carcinoma via regulating epithelial–mesenchymal transition, G2/M phase transition, and PANoptosis
inferred← citeshttps://doi.org/10.62347/sigp9279openalex-snapshot
Potential therapies for HCC involving targeting the ferroptosis pathway
inferred← citeshttps://doi.org/10.70675/59677002z0754z4d00zbc1dzf32a993955a0openalex-snapshot
The STK38 kinase regulates the subcellular distribution of downstream partners by phosphorylating the auto-inhibitory domain of XPO1
inferred← citeshttps://doi.org/10.70675/9566c585z0508z455bz9064z6bb61435b210openalex-snapshot
Glioblastoma resistance to temozolomide : implication of α5β1 integrin and p53 signalling pathways
inferred← citeshttps://doi.org/10.7150/ijbs.36955openalex-snapshot
Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis
inferred← citeshttps://doi.org/10.7150/jca.30342openalex-snapshot
EMP2 acts as a suppressor of melanoma and is negatively regulated by mTOR-mediated autophagy
inferred← citeshttps://doi.org/10.7150/jca.84454openalex-snapshot
An Integrated Analysis Identified TAGLN2 As an Oncogene Indicator Related to Prognosis and Immunity in Pan-Cancer
inferred← citeshttps://doi.org/10.7717/peerj.17690openalex-snapshot
Molecular insights into programmed cell death in esophageal squamous cell carcinoma
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.