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Usage of Platinum Nanoparticles for Anticancer Therapy over Last Decade: A Review

https://doi.org/10.1002/ppsc.202100115
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2 of the 200 references listed on this page are in the Retraction Watch database as retracted (export 2026-10-21): 10.1080/21691401.2019.1677680 (notice 2021-04-06), 10.3389/fchem.2020.00799 (notice 2023-01-12).

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What this work says

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Peptide‐Coated Platinum Nanoparticles with Selective Toxicity against Liver Cancer Cells
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Transformation of a Pt–CeO2 Mechanical Mixture of Pulsed‐Laser‐Ablated Nanoparticles to a Highly Active Catalyst for Carbon Monoxide Oxidation
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Syntheses of Platinum–Sulindac Complexes and Their Nanoparticles as Targeted Anticancer Drugs
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The role of radiotherapy in cancer treatment
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Corrosion‐Activated Chemotherapeutic Function of Nanoparticulate Platinum as a Cisplatin Resistance‐Overcoming Prodrug with Limited Autophagy Induction
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Platinum nanoparticles induced genotoxicity and apoptotic activity in human normal and cancer hepatic cells via oxidative stress‐mediated Bax/Bcl‐2 and caspase‐3 expression
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Nanoparticle formulations of cisplatin for cancer therapy
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Lung Cancer and Personalized Medicine: Novel Therapies and Clinical Management
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Platinum nanoparticles and their cellular uptake and DNA platination at non-cytotoxic concentrations
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The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary
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Effects of SOD/catalase mimetic platinum nanoparticles on radiation-induced apoptosis in human lymphoma U937 cells
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Green synthesis of platinum nanoparticles that induce cell death and G2/M-phase cell cycle arrest in human cervical cancer cells
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Nanotechnology for the treatment of melanoma skin cancer
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Development of Biosensors From Biopolymer Composites
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Selective bio-labeling and induced apoptosis of hematopoietic cancer cells using dual-functional polyethylenimine-caged platinum nanoclusters
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Versatile Pt NCs-based chemotherapeutic agents significantly induce the apoptosis of cisplatin-resistant non-small cell lung cancer
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Photothermal cancer therapy via femtosecond-laser-excited FePt nanoparticles
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Platinum nanoparticles for the photothermal treatment of Neuro 2A cancer cells
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Biosynthesis and characterization of platinum nanoparticles using Iraqi Zahidi dates and evaluation of their biological applications
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FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro
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Lung Cancer: Epidemiology, Etiology, and Prevention
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State of arts on the bio-synthesis of noble metal nanoparticles and their biological application
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Bio-directed synthesis of platinum nanoparticles using aqueous honey solutions and their catalytic applications
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Cytotoxic effects of platinum nanoparticles obtained from pomegranate extract by the green synthesis method on the MCF-7 cell line
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Cisplatin in cancer therapy: Molecular mechanisms of action
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Evaluation of cytotoxic activity of platinum nanoparticles against normal and cancer cells and its anticancer potential through induction of apoptosis
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Mesoporous platinum nanoparticle-based nanoplatforms for combined chemo-photothermal breast cancer therapy
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Wetchemical synthesis of FePt nanoparticles: Tuning of magnetic properties and biofunctionalization for hyperthermia therapy
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Biogenic platinum nanoparticles using black cumin seed and their potential usage as antimicrobial and anticancer agent
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Bio-fabrication of catalytic platinum nanoparticles and their in vitro efficacy against lungs cancer cells line (A549)
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Fabrication of antimicrobial curcumin stabilized platinum nanoparticles and their anti-liver fibrosis activity for potential use in nursing care
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Improved delivery of doxorubicin using rationally designed PEGylated platinum nanoparticles for the treatment of melanoma
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PEGylated FePt@Fe2O3 core-shell magnetic nanoparticles: Potential theranostic applications and in vivo toxicity studies
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Size effect of platinum nanoparticles in simulated anticancer photothermal therapy
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Eco-friendly synthesis and characterization of platinum-copper alloy nanoparticles induce cell death in human cervical cancer cells
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Label-free and competitive aptamer cytosensor based on layer-by-layer assembly of DNA-platinum nanoparticles for ultrasensitive determination of tumor cells
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Preventing UV induced cell damage by scavenging reactive oxygen species with enzyme-mimic Au–Pt nanocomposites
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A cost-effective chemiluminescent biosensor capable of early diagnosing cancer using a combination of magnetic beads and platinum nanoparticles
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Platinum folate nanoparticles toxicity: Cancer vs. normal cells
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Colorectal cancer
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Preparation of platinum nanoparticles by sonochemical reduction of the Pt(IV) ions: role of surfactants
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In Situ Growth of Porous Platinum Nanoparticles on Graphene Oxide for Colorimetric Detection of Cancer Cells
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Synthesis of Gold Nanoparticles in Liquid Environment by Laser Ablation with Geometrically Confined Configurations: Insights To Improve Size Control and Productivity
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A Novel Platinum–Maurocalcine Conjugate Induces Apoptosis of Human Glioblastoma Cells by Acting through the ROS-ERK/AKT-p53 Pathway
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In Situ Biosynthesis of Fluorescent Platinum Nanoclusters: Toward Self-Bioimaging-Guided Cancer Theranostics
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FePt Nanoparticles as an Fe Reservoir for Controlled Fe Release and Tumor Inhibition
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Methotrexate-Modified Superparamagnetic Nanoparticles and Their Intracellular Uptake into Human Cancer Cells
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Synthesis of Platinum Nanoparticles by Reaction of Filamentous Cyanobacteria with Platinum(IV)−Chloride Complex
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Biosynthesis of Platinum Nanoparticles by Escherichia coli MC4100: Can Such Nanoparticles Exhibit Intrinsic Surface Enantioselectivity?
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Inhibition of Cell Division in Escherichia coli by Electrolysis Products from a Platinum Electrode
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Platinum Compounds: a New Class of Potent Antitumour Agents
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Irradiation of Skin with Visible Light Induces Reactive Oxygen Species and Matrix-Degrading Enzymes
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Platinum nanoparticles prepared by a plasma-chemical reduction method
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Dual-action organoplatinum polymeric nanoparticles overcoming drug resistance in ovarian cancer
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Fucoidan-coated coral-like Pt nanoparticles for computed tomography-guided highly enhanced synergistic anticancer effect against drug-resistant breast cancer cells
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The use of gold nanoparticles to enhance radiotherapy in mice
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The current status of treatment for colorectal cancer in China
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Epidemiology of cancer from the oral cavity and oropharynx
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Helium‐based cold atmospheric plasma‐induced reactive oxygen species‐mediated apoptotic pathway attenuated by platinum nanoparticles
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Shear-Activated Nanotherapeutics for Drug Targeting to Obstructed Blood Vessels
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Heterocoagulation of polysaccharide-coated platinum nanoparticles with ovarian-cancer cells
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Review—Chemical and Biological Sensors for Viral Detection
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On the Discovery, Biological Effects, and Use of Cisplatin and Metallocenes in Anticancer Chemotherapy
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Noble Metal Nanoparticles Applications in Cancer
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Skin Cancer and Its Treatment: Novel Treatment Approaches with Emphasis on Nanotechnology
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Gloriosa superba Mediated Synthesis of Platinum and Palladium Nanoparticles for Induction of Apoptosis in Breast Cancer
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Combination of Conventional Chemotherapeutics with Redox-Active Cerium Oxide Nanoparticles—A Novel Aspect in Cancer Therapy
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Platinum Quantum Dots and Their Cytotoxic Effect Towards Myoblast Cancer Cells (C2C12)
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Hyaluronic Acid-Encapsulated Platinum Nanoparticles for Targeted Photothermal Therapy of Breast Cancer
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One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown P. chrysogenum and Their Activity on Bacteria and Cancer Cells
inferredcites →https://doi.org/10.1166/jnn.2018.14874openalex-snapshot
Platinum Nanoparticles Induce Apoptosis on Raw 264.7 Macrophage Cells
inferredcites →https://doi.org/10.1166/jnn.2019.15912openalex-snapshot
Different Cellular Effects of Platinum Nanoparticles on RAW 264.7 Cells
inferredcites →https://doi.org/10.1177/1010428317717259openalex-snapshot
Evaluation of the antitumor activity of platinum nanoparticles in the treatment of hepatocellular carcinoma induced in rats
inferredcites →https://doi.org/10.1177/1091581814522305openalex-snapshot
RETRACTED: Toxicity Study of Cerium Oxide Nanoparticles in Human Neuroblastoma Cells
inferredcites →https://doi.org/10.1186/1477-3155-3-6openalex-snapshot
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inferredcites →https://doi.org/10.1186/1556-276x-8-251openalex-snapshot
Influence of nanoparticles of platinum on chicken embryo development and brain morphology
inferredcites →https://doi.org/10.1186/2228-5326-3-28openalex-snapshot
Evaluation of synthesized platinum nanoparticles on the MCF-7 and HepG-2 cancer cell lines
inferredcites →https://doi.org/10.1186/s11671-016-1653-9openalex-snapshot
In Situ Free Radical Growth Mechanism of Platinum Nanoparticles by Microwave Irradiation and Electrocatalytic Properties
inferredcites →https://doi.org/10.1186/s11671-017-2337-9openalex-snapshot
Synthesis and In Vitro Performance of Polypyrrole-Coated Iron–Platinum Nanoparticles for Photothermal Therapy and Photoacoustic Imaging
inferredcites →https://doi.org/10.1186/s12935-016-0305-6openalex-snapshot
MiR-1244 sensitizes the resistance of non-small cell lung cancer A549 cell to cisplatin
inferredcites →https://doi.org/10.1200/jco.1999.17.7.2055openalex-snapshot
Chemoradiation and Adjuvant Chemotherapy in Cervical Cancer
inferredcites →https://doi.org/10.1201/9780429056925openalex-snapshot
Plants That Fight Cancer
inferredcites →https://doi.org/10.1246/cl.2011.408openalex-snapshot
In Vitro Cytotoxicity and Intracellular Bioimaging of Dendritic Platinum Nanoparticles by Differential Interference Contrast (DIC)
inferredcites →https://doi.org/10.1259/bjr.20150207openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pone.0178277openalex-snapshot
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inferredcites →https://doi.org/10.1371/journal.pone.0180798openalex-snapshot
Platinum nanoparticles induce damage to DNA and inhibit DNA replication
inferredcites →https://doi.org/10.1515/gps-2020-0031openalex-snapshot
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inferredcites →https://doi.org/10.1515/ntrev-2016-0014openalex-snapshot
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inferredcites →https://doi.org/10.1615/critreveukaryotgeneexpr.2018022771openalex-snapshot
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inferredcites →https://doi.org/10.1634/theoncologist.10-10-780openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s125154openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s156984openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s32678openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s43417openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s49612openalex-snapshot
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inferredcites →https://doi.org/10.2147/ijn.s62630openalex-snapshot
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inferredcites →https://doi.org/10.2217/nnm-2017-0202openalex-snapshot
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inferredcites →https://doi.org/10.2217/nnm.09.85openalex-snapshot
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inferredcites →https://doi.org/10.2217/nnm.15.77openalex-snapshot
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inferredcites →https://doi.org/10.3109/1040841x.2015.1018131openalex-snapshot
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
inferredcites →https://doi.org/10.3389/fchem.2020.00799openalex-snapshot
RETRACTED: Green Synthesis of Metallic Nanoparticles and Their Potential Applications to Treat Cancer
inferredcites →https://doi.org/10.3389/fphar.2018.00119openalex-snapshot
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inferredcites →https://doi.org/10.3390/c3020018openalex-snapshot
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inferredcites →https://doi.org/10.3390/catal10111311openalex-snapshot
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inferredcites →https://doi.org/10.3390/cells8050444openalex-snapshot
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inferredcites →https://doi.org/10.3390/cells8091105openalex-snapshot
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inferredcites →https://doi.org/10.3390/ijms20071560openalex-snapshot
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inferredcites →https://doi.org/10.3390/ijms21051619openalex-snapshot
A Facile One-Pot Synthesis of Versatile PEGylated Platinum Nanoflowers and Their Application in Radiation Therapy
inferredcites →https://doi.org/10.3390/ma12060909openalex-snapshot
Nanocomplexes of Graphene Oxide and Platinum Nanoparticles against Colorectal Cancer Colo205, HT-29, HTC-116, SW480, Liver Cancer HepG2, Human Breast Cancer MCF-7, and Adenocarcinoma LNCaP and Human Cervical Hela B Cell Lines
inferredcites →https://doi.org/10.3390/nano8050319openalex-snapshot
Silver Nanoparticles: Synthetic Routes, In Vitro Toxicity and Theranostic Applications for Cancer Disease
inferredcites →https://doi.org/10.3390/nano9081089openalex-snapshot
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inferredcites →https://doi.org/10.3390/nano9091195openalex-snapshot
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inferredcites →https://doi.org/10.3390/nano9121719openalex-snapshot
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inferredcites →https://doi.org/10.3390/pharmaceutics10040181openalex-snapshot
Targeted Theranostic Nanoparticles for Brain Tumor Treatment
inferredcites →https://doi.org/10.3390/polym11040733openalex-snapshot
Graphene Oxide–Platinum Nanoparticle Nanocomposites: A Suitable Biocompatible Therapeutic Agent for Prostate Cancer
inferredcites →https://doi.org/10.3831/kpi.2016.19.012openalex-snapshot
Biosynthesized Platinum Nanoparticles Inhibit the Proliferation of Human Lung-Cancer Cells in vitro and Delay the Growth of a Human Lung-Tumor Xenograft in vivo
inferredcites →https://doi.org/10.4061/2011/343125openalex-snapshot
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inferredcites →https://doi.org/10.4143/crt.2019.138openalex-snapshot
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inferredcites →https://doi.org/10.4172/2161-0444.1000259openalex-snapshot
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inferredcites →https://doi.org/10.5114/aoms.2016.58925openalex-snapshot
Investigation of platinum nanoparticle properties against U87 glioblastoma multiforme
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What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Inhibitory Effects of Platinum Nanoparticles Coated with Polyethylene Glycol and Loaded with Rutin on a Breast Cancer Cell Line
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pH‐Responsive Multicomponent Nanocomposite for Enhanced Reactive Oxygen Species Generation and Targeted Apoptosis‐Induced Synergistic Cancer Treatment
inferred← citeshttps://doi.org/10.1002/jcc.70342openalex-snapshot
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Recent advances in platinum nanoparticles: from synthesis and characterization to catalytic and biomedical applications
inferred← citeshttps://doi.org/10.1007/s11051-024-06212-yopenalex-snapshot
Novel water-soluble gelatin-based platinum nanoparticles for targeted cancer therapy with enhanced cytotoxicity
inferred← citeshttps://doi.org/10.1007/s11051-026-06735-6openalex-snapshot
Acute toxicity and tissue deposition of graphene oxide decorated with platinum nanoparticles following intraperitoneal administration in rats
inferred← citeshttps://doi.org/10.1007/s44373-025-00066-2openalex-snapshot
Electrochemical detection techniques and usage of nanoparticles in cancer detection
inferred← citeshttps://doi.org/10.1016/j.arabjc.2023.105567openalex-snapshot
Inhibitory effects of platinum nanoparticles coated with polyethylene glycol and conjugated with Rutin on the MCF-7 breast cancer cell line
inferred← citeshttps://doi.org/10.1016/j.cbi.2024.111365openalex-snapshot
Platinum as both a drug and its modulator – Do platinum nanoparticles influence cisplatin activity?
inferred← citeshttps://doi.org/10.1016/j.cej.2024.150067openalex-snapshot
Functional inorganic nanomaterials for optical cancer theranostics
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A physicochemical and spectroscopic characterization of novel erlotinib conjugates with platinum nanoparticles
inferred← citeshttps://doi.org/10.1016/j.ejpb.2025.114866openalex-snapshot
Platinum nanoparticles interact with epirubicin in size dependent manner and affect its biological activity
inferred← citeshttps://doi.org/10.1016/j.genrep.2026.102519openalex-snapshot
Advancement in miRNA-based nano-biosensing for cancer detection: A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.jtherbio.2026.104428openalex-snapshot
Reactive oxygen species mediated-photo-sono-ablation of melanoma cells using a novel nanocomposite of platinum-polypyrrole as a nanozyme
inferred← citeshttps://doi.org/10.1016/j.microc.2024.110280openalex-snapshot
Platinum-based nanoparticles: A review of synthesis methods, surface functionalization, and their applications
inferred← citeshttps://doi.org/10.1016/j.nxnano.2025.100231openalex-snapshot
Theoretical study in comparison of astatine adsorptions on metal carrier materials for targeted alpha therapy applications
inferred← citeshttps://doi.org/10.1021/acsami.2c22375openalex-snapshot
Inter-Organelle Contact Sites Mediate the Intracellular Antioxidant Activity of Platinum Nanozymes: A New Perspective on Cell–Nanoparticle Interaction and Signaling
inferred← citeshttps://doi.org/10.1021/acsnano.5c03785openalex-snapshot
Liquid Metal Amplified Charge Separation in Photocatalytic Micro/Nanomotors for Antibacterial Therapy
inferred← citeshttps://doi.org/10.1038/s41598-024-69724-6openalex-snapshot
Influence of silver nanoparticles’ size on their direct interactions with doxorubicin and its biological effects
inferred← citeshttps://doi.org/10.1039/d4nr05199hopenalex-snapshot
Design of engineered nanoparticles for biomedical applications by computational modeling
inferred← citeshttps://doi.org/10.1080/10717544.2024.2445257openalex-snapshot
Exploring the efficacy and constraints of platinum nanoparticles as adjuvant therapy in silicosis management
inferred← citeshttps://doi.org/10.1088/2057-1976/ad795dopenalex-snapshot
Assessing anticancer properties of PEGylated platinum nanoparticles on human breast cancer cell lines using in-vitro assays
inferred← citeshttps://doi.org/10.1142/s1793292024300081openalex-snapshot
Harnessing Metal Nanoparticles: Revolutionizing Cancer Therapy Through Targeted Drug Delivery and Tumor Microenvironment Modulation
inferred← citeshttps://doi.org/10.1186/s12935-025-03893-wopenalex-snapshot
Synthesis of 5-Fluorouracil (5-FU) coated platinum nanoparticles and apoptotic effects on U87 human glioblastoma cells
inferred← citeshttps://doi.org/10.1186/s12943-025-02421-8openalex-snapshot
Platinum-based functional nanomaterials: mechanisms and therapeutic strategies in cancer radiotherapy sensitization
inferred← citeshttps://doi.org/10.2109/jcersj2.23159openalex-snapshot
Preparation of platinum nanoparticles using a continuous-flow precision synthesis system
inferred← citeshttps://doi.org/10.3390/antiox11050986openalex-snapshot
Platinum Nanoparticles: The Potential Antioxidant in the Human Lung Cancer Cells
inferred← citeshttps://doi.org/10.3390/biomedicines11071857openalex-snapshot
Design and Evaluation of Composite Magnetic Iron–Platinum Nanowires for Targeted Cancer Nanomedicine
inferred← citeshttps://doi.org/10.3390/ijms23169404openalex-snapshot
Functionalized Platinum Nanoparticles with Biomedical Applications
inferred← citeshttps://doi.org/10.3390/jnt4030017openalex-snapshot
Smart Platinum Nanostructures: A Journey from Synthesis to Advanced Theranostic Applications
inferred← citeshttps://doi.org/10.3390/jnt6040030openalex-snapshot
Nanotechnological Innovations in the Treatment and Diagnosis of Viral Pathogens: Biomedical and Macromolecular Insights
inferred← citeshttps://doi.org/10.3390/pharmaceutics15071932openalex-snapshot
Functionalized Metal Nanoparticles in Cancer Therapy
inferred← citeshttps://doi.org/10.3390/pharmaceutics16091162openalex-snapshot
Platinum Group Metals Nanoparticles in Breast Cancer Therapy
inferred← citeshttps://doi.org/10.58803/jlar.v2i5.31openalex-snapshot
Advancements in the Utilization of Metal Nanoparticles for Breast Cancer Treatment: An In Vivo Studies Update
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