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An NIR‐Fluorophore‐Based Theranostic for Selective Initiation of Tumor Pyroptosis‐Induced Immunotherapy
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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NaCl Nanoparticles as a Cancer Therapeutic
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Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH
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A General Strategy for Macrotheranostic Prodrug Activation: Synergy between the Acidic Tumor Microenvironment and Bioorthogonal Chemistry
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Inside Cover: Synergistic N‐Heterocyclic Carbene/Palladium‐Catalyzed Umpolung 1,4‐Addition of Aryl Iodides to Enals (Angew. Chem. Int. Ed. 1/2020)
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Self‐Boosting Catalytic Nanoreactors Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis
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Activation of Pyroptosis by Membrane‐Anchoring AIE Photosensitizer Design: New Prospect for Photodynamic Cancer Cell Ablation
inferredcites →https://doi.org/10.1007/bf00689804openalex-snapshot
NAD(P)H:Quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues
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A near-infrared emissive Al3+ sensing platform for specific detection in solution, cells and probing DNase activity
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A review of NIR dyes in cancer targeting and imaging
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IDO-inhibitor potentiated immunogenic chemotherapy abolishes primary tumor growth and eradicates metastatic lesions by targeting distinct compartments within tumor microenvironment
inferredcites →https://doi.org/10.1016/j.canlet.2019.02.014openalex-snapshot
Metformin induces human esophageal carcinoma cell pyroptosis by targeting the miR-497/PELP1 axis
inferredcites →https://doi.org/10.1016/j.coi.2013.02.009openalex-snapshot
Cancer immunotherapy strategies based on overcoming barriers within the tumor microenvironment
inferredcites →https://doi.org/10.1016/j.dyepig.2018.09.059openalex-snapshot
A ratiometric fluorescent probe for the detection of peroxynitrite with simple synthesis and large emission shift and its application in cells image
inferredcites →https://doi.org/10.1016/j.tcb.2017.05.005openalex-snapshot
Gasdermins: Effectors of Pyroptosis
inferredcites →https://doi.org/10.1016/j.tibs.2016.10.004openalex-snapshot
Pyroptosis: Gasdermin-Mediated Programmed Necrotic Cell Death
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Reactivity-Based Organic Theranostic Bioprobes
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In-Situ Imaging of Azoreductase Activity in the Acute and Chronic Ulcerative Colitis Mice by a Near-Infrared Fluorescent Probe
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Epigenetics-Based Tumor Cells Pyroptosis for Enhancing the Immunological Effect of Chemotherapeutic Nanocarriers
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Cytosolic NQO1 Enzyme-Activated Near-Infrared Fluorescence Imaging and Photodynamic Therapy with Polymeric Vesicles
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Near-Infrared Fluorescent Macromolecular Reporters for Real-Time Imaging and Urinalysis of Cancer Immunotherapy
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Na2S2O8 Nanoparticles Trigger Antitumor Immunotherapy through Reactive Oxygen Species Storm and Surge of Tumor Osmolarity
inferredcites →https://doi.org/10.1021/jacs.7b12817openalex-snapshot
Ultrabright and Fluorogenic Probes for Multicolor Imaging and Tracking of Lipid Droplets in Cells and Tissues
inferredcites →https://doi.org/10.1038/cr.2016.149openalex-snapshot
Innate immune signaling and regulation in cancer immunotherapy
inferredcites →https://doi.org/10.1038/cr.2017.133openalex-snapshot
Plasma membrane changes during programmed cell deaths
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T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases
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Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
inferredcites →https://doi.org/10.1038/nature15541openalex-snapshot
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
inferredcites →https://doi.org/10.1038/nature22393openalex-snapshot
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
inferredcites →https://doi.org/10.1038/ncomms13193openalex-snapshot
Photothermal therapy with immune-adjuvant nanoparticles together with checkpoint blockade for effective cancer immunotherapy
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DNA exonuclease Trex1 regulates radiotherapy-induced tumour immunogenicity
inferredcites →https://doi.org/10.1038/nnano.2017.113openalex-snapshot
Antigen-capturing nanoparticles improve the abscopal effect and cancer immunotherapy
inferredcites →https://doi.org/10.1038/nrc.2018.6openalex-snapshot
Using immunotherapy to boost the abscopal effect
inferredcites →https://doi.org/10.1038/nri.2016.147openalex-snapshot
Programmed cell death as a defence against infection
inferredcites →https://doi.org/10.1038/nrm3999openalex-snapshot
Live to die another way: modes of programmed cell death and the signals emanating from dying cells
inferredcites →https://doi.org/10.1038/s41418-017-0012-4openalex-snapshot
Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
inferredcites →https://doi.org/10.1038/s41422-018-0090-yopenalex-snapshot
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis
inferredcites →https://doi.org/10.1038/s41551-018-0236-8openalex-snapshot
TLR7/8-agonist-loaded nanoparticles promote the polarization of tumour-associated macrophages to enhance cancer immunotherapy
inferredcites →https://doi.org/10.1038/s41586-020-2071-9openalex-snapshot
Gasdermin E suppresses tumour growth by activating anti-tumour immunity
inferredcites →https://doi.org/10.1038/s41586-020-2079-1openalex-snapshot
A bioorthogonal system reveals antitumour immune function of pyroptosis
inferredcites →https://doi.org/10.1126/sciadv.abb2712openalex-snapshot
AIEgen-coupled upconversion nanoparticles eradicate solid tumors through dual-mode ROS activation
inferredcites →https://doi.org/10.1126/sciadv.abd1631openalex-snapshot
Size-transformable antigen-presenting cell–mimicking nanovesicles potentiate effective cancer immunotherapy
inferredcites →https://doi.org/10.1126/science.aaa4971openalex-snapshot
Neoantigens in cancer immunotherapy
inferredcites →https://doi.org/10.1126/science.aaa8172openalex-snapshot
The future of immune checkpoint therapy
inferredcites →https://doi.org/10.1126/science.aaf2154openalex-snapshot
Programmed necrosis in inflammation: Toward identification of the effector molecules
inferredcites →https://doi.org/10.1126/science.aar4060openalex-snapshot
Cancer immunotherapy using checkpoint blockade
inferredcites →https://doi.org/10.1126/scitranslmed.3006504openalex-snapshot
Up-Regulation of PD-L1, IDO, and T regs in the Melanoma Tumor Microenvironment Is Driven by CD8 + T Cells
inferredcites →https://doi.org/10.1146/annurev-immunol-032712-100008openalex-snapshot
Immunogenic Cell Death in Cancer Therapy
inferredcites →https://doi.org/10.1158/0008-5472.can-16-0549openalex-snapshot
Abscopal Effects of Radiotherapy Are Enhanced by Combined Immunostimulatory mAbs and Are Dependent on CD8 T Cells and Crosspriming
inferredcites →https://doi.org/10.15252/embj.2019101638openalex-snapshot
Extrinsic and intrinsic apoptosis activate pannexin‐1 to drive NLRP3 inflammasome assembly
inferredcites →https://doi.org/10.3390/cancers8120106openalex-snapshot
Advances in Cancer Immunotherapy in Solid Tumors
inferredcites →https://doi.org/10.4049/jimmunol.1202688openalex-snapshot
IL-1β Promotes Antimicrobial Immunity in Macrophages by Regulating TNFR Signaling and Caspase-3 Activation
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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A Microenvironment Dual‐Responsive Nano‐Drug Equipped with PD‐L1 Blocking Peptide Triggers Immunogenic Pyroptosis for Prostate Cancer Self‐Synergistic Immunotherapy
inferred← citeshttps://doi.org/10.1002/adfm.202310364openalex-snapshot
Combination of Cryo‐Shocked M1 Macrophages and Lonidamine Nanodrugs Enables Potent Chemo‐Immunotherapy
inferred← citeshttps://doi.org/10.1002/adfm.202411002openalex-snapshot
The Midas Touch by Internal Stimuli: Activatable Luminogens with Near‐Infrared Aggregation‐Induced Emission for Potent Bioimaging and Theranostics
inferred← citeshttps://doi.org/10.1002/adhm.202301266openalex-snapshot
Nanomaterials for Disease Treatment by Modulating the Pyroptosis Pathway
inferred← citeshttps://doi.org/10.1002/advs.202202914openalex-snapshot
Pyroptosis Remodeling Tumor Microenvironment to Enhance Pancreatic Cancer Immunotherapy Driven by Membrane Anchoring Photosensitizer
inferred← citeshttps://doi.org/10.1002/advs.202305382openalex-snapshot
Dual‐Responsive Supramolecular Polymeric Nanomedicine for Self‐Cascade Amplified Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/exp.20220001openalex-snapshot
Recent progress of metal‐based nanomaterials with anti‐tumor biological effects for enhanced cancer therapy
inferred← citeshttps://doi.org/10.1002/smll.202305526openalex-snapshot
Macrophages‐Based Biohybrid Microrobots for Breast Cancer Photothermal Immunotherapy by Inducing Pyroptosis
inferred← citeshttps://doi.org/10.1002/smll.202411787openalex-snapshot
Activatable Molecular Probes With Clinical Promise for NIR‐II Fluorescent Imaging
inferred← citeshttps://doi.org/10.1007/s40843-026-4228-yopenalex-snapshot
Smart yet safe: a tumor-targeting scaffold for activatable NIR photosensitizers with complete toxicity reversal
inferred← citeshttps://doi.org/10.1016/j.actbio.2023.05.018openalex-snapshot
Cyclic amplification of intracellular ROS boosts enzymatic prodrug activation for enhanced chemo-immunotherapy
inferred← citeshttps://doi.org/10.1016/j.addr.2023.114725openalex-snapshot
Activatable dual-functional molecular agents for imaging-guided cancer therapy
inferred← citeshttps://doi.org/10.1016/j.addr.2023.114793openalex-snapshot
Activatable fluorescent probes for real-time imaging-guided tumor therapy
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.06.026openalex-snapshot
Pyroptosis: Induction and inhibition strategies for immunotherapy of diseases
inferred← citeshttps://doi.org/10.1016/j.apsb.2025.05.021openalex-snapshot
Nanomedicine-induced pyroptosis for anti-tumor immunotherapy: Mechanism analysis and application prospects
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2023.10.027openalex-snapshot
Engineering materials for pyroptosis induction in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121803openalex-snapshot
Self-immolative polyprodrug-based tumor-specific cascade amplificated drug release nanosystem for orchestrated synergistic cancer therapy
inferred← citeshttps://doi.org/10.1016/j.ccr.2022.214438openalex-snapshot
Biomarker-activatable probes based on smart AIEgens for fluorescence and optoacoustic imaging
inferred← citeshttps://doi.org/10.1016/j.cej.2023.146748openalex-snapshot
Laser boosting the influx of calcium ions to enhance gasdermin e-dependent pyroptosis driven by a dual-layer polydopamine nanoagonist
inferred← citeshttps://doi.org/10.1016/j.celbio.2025.100044openalex-snapshot
Mutually reinforced activatable NIR fluorescence/MR bimodal imaging enabled by tumor-specific biomarker amplification
inferred← citeshttps://doi.org/10.1016/j.matdes.2024.112731openalex-snapshot
Engineering metal-organic framework nanoparticles trigger pyroptosis to boost colon cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.matt.2022.08.026openalex-snapshot
Emerging pyroptosis-engineered nanobiotechnologies regulate cancers and inflammatory diseases: A double-edged sword
inferred← citeshttps://doi.org/10.1016/j.mtbio.2024.101191openalex-snapshot
Applications of pyroptosis activators in tumor immunotherapy
inferred← citeshttps://doi.org/10.1016/j.mtchem.2022.100928openalex-snapshot
A novel fluorescent probe derived from isophorone and its application in imaging in vivo hypoxia
inferred← citeshttps://doi.org/10.1016/j.nantod.2022.101727openalex-snapshot
Endogenous/exogenous stimulies inspired polyprodrug nano-inducer switches pyroptosis path for promoting antitumor immunity
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c01189openalex-snapshot
NQO-1 Enzyme-Activated NIR Theranostic Agent for Pancreatic Cancer
inferred← citeshttps://doi.org/10.1021/acs.analchem.2c03436openalex-snapshot
Family of hNQO1 Activatable Near-Infrared Fluoro-Photoacoustic Probes for Diagnosis of Wound Infection and Ulcerative Colitis
inferred← citeshttps://doi.org/10.1021/acs.analchem.4c06892openalex-snapshot
Tumor Microenvironment-Responsive Lipid Peroxidation Amplifier: Harnessing Ferroptosis Resistance to Devastate the Ferroptosis Defense System
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c00022openalex-snapshot
Self-Assembly of Ru3-Aptamer Nanoparticles Triggers Pyroptosis through Photoredox Catalysis of NADH and Lysosomal Disruption
inferred← citeshttps://doi.org/10.1021/acsmaterialslett.4c00135openalex-snapshot
Lysosome-Anchoring Activation Design of Type I Photosensitizer Evokes Pyroptosis and Antitumor Immunity
inferred← citeshttps://doi.org/10.1021/jacsau.2c00591openalex-snapshot
Immuno-photodynamic Therapy (IPDT): Organic Photosensitizers and Their Application in Cancer Ablation
inferred← citeshttps://doi.org/10.1039/d1cs00307kopenalex-snapshot
Activity-based NIR fluorescent probes based on the versatile hemicyanine scaffold: design strategy, biomedical applications, and outlook
inferred← citeshttps://doi.org/10.1039/d2sc05982gopenalex-snapshot
Single-atom engineering of hemicyanine and its amphiphilic derivative for optimized near infrared phototheranostics
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A dual-amplified ROS-responsive nanosystem with self-accelerating drug release for synergistic chemotherapy
inferred← citeshttps://doi.org/10.1039/d5cc06440fopenalex-snapshot
Sulfur- or selenium-substituted Nile blue-based superoxide radical generators for precise photodynamic therapy and immunotherapy
inferred← citeshttps://doi.org/10.1039/d6tb01590eopenalex-snapshot
Dual mitochondrial-targeting nanoplatform integrating cuproptosis and pyroptosis for robust antitumor immune activation
inferred← citeshttps://doi.org/10.1186/s12951-024-02763-3openalex-snapshot
Nanoparticle-mediated cell pyroptosis: a new therapeutic strategy for inflammatory diseases and cancer
inferred← citeshttps://doi.org/10.1186/s12951-026-04343-zopenalex-snapshot
Leveraging the crosstalk between cGAS-STING and pyroptosis by nanomedicine to enhance antitumor immunity
inferred← citeshttps://doi.org/10.1631/bdm.2400339openalex-snapshot
A redox-responsive nanovaccine for cytosolic delivery of antigen and adjuvant to enhance cancer immunotherapy
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Nanomaterials Enhance Pyroptosis-Based Tumor Immunotherapy
inferred← citeshttps://doi.org/10.26599/ntm.2022.9130001openalex-snapshot
Evoking pyroptosis with nanomaterials for cancer immunotherapy: Current boom and novel outlook
inferred← citeshttps://doi.org/10.3389/fcell.2022.779269openalex-snapshot
The Pyroptosis-Related Long Noncoding RNA Signature Predicts Prognosis and Indicates Immunotherapeutic Efficiency in Hepatocellular Carcinoma
inferred← citeshttps://doi.org/10.3389/fchem.2025.1626741openalex-snapshot
Rational design of a NIR fluorescent probe for highly selective sensing of NAD(P)H quinone oxidoreductase 1 in living systems
inferred← citeshttps://doi.org/10.3389/fsurg.2022.935765openalex-snapshot
Construction of prognostic signature of patients with oral squamous cell carcinoma based on pyroptosis-related long non-coding RNAs
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A GSH-Activatable Theranostic Prodrug Based on Photoinduced Electron Transfer for Cancer Fluorescence Imaging and Therapy
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Pyroptosis in inflammatory diseases and cancer
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