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HIF1α Modulates Cell Fate Reprogramming Through Early Glycolytic Shift and Upregulation of PDK1–3 and PKM2

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Prevalence of mitochondrial DNA disease in adults
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Inhibitory Effects of Hypoxia on Metabolic Switch and Osteogenic Differentiation of Human Mesenchymal Stem Cells
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Hypoxia induces re-entry of committed cells into pluripotency
inferredcites →https://doi.org/10.1002/stem.307openalex-snapshot
Human Induced Pluripotent Stem Cell Lines Show Stress Defense Mechanisms and Mitochondrial Regulation Similar to Those of Human Embryonic Stem Cells
inferredcites →https://doi.org/10.1002/stem.321openalex-snapshot
Hemangioblastic Derivatives from Human Induced Pluripotent Stem Cells Exhibit Limited Expansion and Early Senescence
inferredcites →https://doi.org/10.1002/stem.404openalex-snapshot
The Senescence-Related Mitochondrial/Oxidative Stress Pathway is Repressed in Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1002/stem.542openalex-snapshot
Mitochondrial DNA Integrity Is Essential For Mitochondrial Maturation During Differentiation of Neural Stem Cells
inferredcites →https://doi.org/10.1002/stem.590openalex-snapshot
Mitochondrial Function Controls Proliferation and Early Differentiation Potential of Embryonic Stem Cells
inferredcites →https://doi.org/10.1002/stem.683openalex-snapshot
Human Induced Pluripotent Stem Cells Harbor Homoplasmic and Heteroplasmic Mitochondrial DNA Mutations While Maintaining Human Embryonic Stem Cell–like Metabolic Reprogramming
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Detecting Heteroplasmy from High-Throughput Sequencing of Complete Human Mitochondrial DNA Genomes
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Pyruvate kinase isozyme type M2 (PKM2) interacts and cooperates with Oct-4 in regulating transcription
inferredcites →https://doi.org/10.1016/j.cell.2005.02.001openalex-snapshot
Mitochondria, Oxidants, and Aging
inferredcites →https://doi.org/10.1016/j.cell.2006.07.024openalex-snapshot
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
inferredcites →https://doi.org/10.1016/j.cell.2007.11.019openalex-snapshot
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
inferredcites →https://doi.org/10.1016/j.cell.2008.04.043openalex-snapshot
Integration of External Signaling Pathways with the Core Transcriptional Network in Embryonic Stem Cells
inferredcites →https://doi.org/10.1016/j.cell.2010.04.010openalex-snapshot
Derivation of Pre-X Inactivation Human Embryonic Stem Cells under Physiological Oxygen Concentrations
inferredcites →https://doi.org/10.1016/j.cell.2011.03.054openalex-snapshot
Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1
inferredcites →https://doi.org/10.1016/j.cell.2012.01.021openalex-snapshot
Hypoxia-Inducible Factors in Physiology and Medicine
inferredcites →https://doi.org/10.1016/j.cell.2012.11.039openalex-snapshot
A Molecular Roadmap of Reprogramming Somatic Cells into iPS Cells
inferredcites →https://doi.org/10.1016/j.cmet.2006.01.012openalex-snapshot
HIF-1 mediates adaptation to hypoxia by actively downregulating mitochondrial oxygen consumption
inferredcites →https://doi.org/10.1016/j.cmet.2006.02.002openalex-snapshot
HIF-1-mediated expression of pyruvate dehydrogenase kinase: A metabolic switch required for cellular adaptation to hypoxia
inferredcites →https://doi.org/10.1016/j.cmet.2011.06.011openalex-snapshot
Somatic Oxidative Bioenergetics Transitions into Pluripotency-Dependent Glycolysis to Facilitate Nuclear Reprogramming
inferredcites →https://doi.org/10.1016/j.cmet.2011.06.017openalex-snapshot
Pyruvate Kinase Triggers a Metabolic Feedback Loop that Controls Redox Metabolism in Respiring Cells
inferredcites →https://doi.org/10.1016/j.cmet.2013.06.005openalex-snapshot
Mitochondrial Regulation in Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.cub.2010.11.049openalex-snapshot
A High Proliferation Rate Is Required for Cell Reprogramming and Maintenance of Human Embryonic Stem Cell Identity
inferredcites →https://doi.org/10.1016/j.stem.2009.08.001openalex-snapshot
Hypoxia Enhances the Generation of Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2009.12.001openalex-snapshot
Vitamin C Enhances the Generation of Mouse and Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2010.07.007openalex-snapshot
Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche
inferredcites →https://doi.org/10.1016/j.stem.2010.07.017openalex-snapshot
Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells
inferredcites →https://doi.org/10.1016/j.stem.2010.11.015openalex-snapshot
Reprogramming of Human Primary Somatic Cells by OCT4 and Chemical Compounds
inferredcites →https://doi.org/10.1016/j.stem.2010.12.003openalex-snapshot
Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture
inferredcites →https://doi.org/10.1016/j.stem.2012.05.005openalex-snapshot
Induced Pluripotent Stem Cells: Past, Present, and Future
inferredcites →https://doi.org/10.1016/j.stem.2012.10.002openalex-snapshot
Metabolic Plasticity in Stem Cell Homeostasis and Differentiation
inferredcites →https://doi.org/10.1016/j.stem.2012.10.005openalex-snapshot
Metabolic Regulation in Pluripotent Stem Cells during Reprogramming and Self-Renewal
inferredcites →https://doi.org/10.1016/j.tibs.2009.12.001openalex-snapshot
Regulatory crosstalk of the metabolic network
inferredcites →https://doi.org/10.1016/j.tibs.2012.04.003openalex-snapshot
Rocking cell metabolism: revised functions of the key glycolytic regulator PKM2 in cancer
inferredcites →https://doi.org/10.1038/290457a0openalex-snapshot
Sequence and organization of the human mitochondrial genome
inferredcites →https://doi.org/10.1038/480190aopenalex-snapshot
Sacrifice for survival
inferredcites →https://doi.org/10.1038/cdd.2011.9openalex-snapshot
Genomic instability in induced stem cells
inferredcites →https://doi.org/10.1038/cr.2011.177openalex-snapshot
The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming
inferredcites →https://doi.org/10.1038/emboj.2011.401openalex-snapshot
UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells
inferredcites →https://doi.org/10.1038/emboj.2012.71openalex-snapshot
HIF1α induced switch from bivalent to exclusively glycolytic metabolism during ESC‐to‐EpiSC/hESC transition
inferredcites →https://doi.org/10.1038/nature06734openalex-snapshot
The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth
inferredcites →https://doi.org/10.1038/nature08311openalex-snapshot
Linking the p53 tumour suppressor pathway to somatic cell reprogramming
inferredcites →https://doi.org/10.1038/nature08802openalex-snapshot
Heteroplasmic mitochondrial DNA mutations in normal and tumour cells
inferredcites →https://doi.org/10.1038/nature09017openalex-snapshot
Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature09342openalex-snapshot
Epigenetic memory in induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature09805openalex-snapshot
Somatic coding mutations in human induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nature09871openalex-snapshot
Copy number variation and selection during reprogramming to pluripotency
inferredcites →https://doi.org/10.1038/nbt.2052openalex-snapshot
Donor cell type can influence the epigenome and differentiation potential of human induced pluripotent stem cells
inferredcites →https://doi.org/10.1038/nbt0709-604openalex-snapshot
Metabolic reconfiguration precedes transcriptional regulation in the antioxidant response
inferredcites →https://doi.org/10.1038/nbt1374openalex-snapshot
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
inferredcites →https://doi.org/10.1038/ncb2239openalex-snapshot
Incomplete DNA methylation underlies a transcriptional memory of somatic cells in human iPS cells
inferredcites →https://doi.org/10.1038/nchembio.364openalex-snapshot
Metabolic oxidation regulates embryonic stem cell differentiation
inferredcites →https://doi.org/10.1038/ng.2007.63openalex-snapshot
A reduction of mitochondrial DNA molecules during embryogenesis explains the rapid segregation of genotypes
inferredcites →https://doi.org/10.1038/ng.258openalex-snapshot
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes
inferredcites →https://doi.org/10.1038/ng1769openalex-snapshot
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
inferredcites →https://doi.org/10.1038/nm1756openalex-snapshot
SUMOylation of Krüppel-like transcription factor 5 acts as a molecular switch in transcriptional programs of lipid metabolism involving PPAR-δ
inferredcites →https://doi.org/10.1038/nrc2817openalex-snapshot
Targeting metabolic transformation for cancer therapy
inferredcites →https://doi.org/10.1038/nrc2981openalex-snapshot
Regulation of cancer cell metabolism
inferredcites →https://doi.org/10.1038/nrc3038openalex-snapshot
Otto Warburg's contributions to current concepts of cancer metabolism
inferredcites →https://doi.org/10.1038/nrg1606openalex-snapshot
Mitochondrial DNA mutations in human disease
inferredcites →https://doi.org/10.1038/nrm3584openalex-snapshot
Origins and implications of pluripotent stem cell variability and heterogeneity
inferredcites →https://doi.org/10.1038/onc.2012.510openalex-snapshot
The growing complexity of HIF-1α’s role in tumorigenesis: DNA repair and beyond
inferredcites →https://doi.org/10.1038/sj.onc.1209604openalex-snapshot
Mitochondrial DNA mutations in human cancer
inferredcites →https://doi.org/10.1038/sj.onc.1209607openalex-snapshot
Mitochondrial mutations in cancer
inferredcites →https://doi.org/10.1042/bj20021614openalex-snapshot
Failure to increase glucose consumption through the pentose-phosphate pathway results in the death of glucose-6-phosphate dehydrogenase gene-deleted mouse embryonic stem cells subjected to oxidative stress
inferredcites →https://doi.org/10.1046/j.1432-1327.1998.2570192.xopenalex-snapshot
Bioenergetic consequences of accumulating the common 4977‐bp mitochondrial DNA deletion
inferredcites →https://doi.org/10.1056/nejmra022567openalex-snapshot
Mitochondrial Respiratory-Chain Diseases
inferredcites →https://doi.org/10.1073/pnas.0408894102openalex-snapshot
mtDNA mutations increase tumorigenicity in prostate cancer
inferredcites →https://doi.org/10.1073/pnas.0501283102openalex-snapshot
Low O 2 tensions and the prevention of differentiation of hES cells
inferredcites →https://doi.org/10.1073/pnas.0910012107openalex-snapshot
Neural differentiation of human induced pluripotent stem cells follows developmental principles but with variable potency
inferredcites →https://doi.org/10.1073/pnas.1310291110openalex-snapshot
Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts
inferredcites →https://doi.org/10.1073/pnas.76.4.1967openalex-snapshot
Rapid evolution of animal mitochondrial DNA.
inferredcites →https://doi.org/10.1073/pnas.89.16.7370openalex-snapshot
A pattern of accumulation of a somatic deletion of mitochondrial DNA in aging human tissues.
inferredcites →https://doi.org/10.1073/pnas.91.19.8739openalex-snapshot
Mitochondrial DNA sequence variation in human evolution and disease.
inferredcites →https://doi.org/10.1073/pnas.94.13.6658openalex-snapshot
c-Myc transactivation of LDH-A : Implications for tumor metabolism and growth
inferredcites →https://doi.org/10.1074/jbc.m111.236737openalex-snapshot
Krüppel-like Factor 4 (KLF4) Activates the Transcription of the Gene for the Platelet Isoform of Phosphofructokinase (PFKP) in Breast Cancer
inferredcites →https://doi.org/10.1074/jbc.m803508200openalex-snapshot
Induction of Pyruvate Dehydrogenase Kinase-3 by Hypoxia-inducible Factor-1 Promotes Metabolic Switch and Drug Resistance
inferredcites →https://doi.org/10.1089/104303403764539305openalex-snapshot
Comparison of Three Retroviral Vector Systems for Transduction of Nonobese Diabetic/Severe Combined Immunodeficiency Mice Repopulating Human CD34 + Cord Blood Cells
inferredcites →https://doi.org/10.1096/fj.02-1062fjeopenalex-snapshot
Activation of the hypoxia‐inducible factor pathway and stimulation of angiogenesis by application of prolyl hydroxylase inhibitors
inferredcites →https://doi.org/10.1101/gad.1399906openalex-snapshot
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
inferredcites →https://doi.org/10.1111/j.1365-2184.2009.00612.xopenalex-snapshot
Transmitochondrial embryonic stem cells containing pathogenic mtDNA mutations are compromised in neuronal differentiation
inferredcites →https://doi.org/10.1111/j.1474-9726.2007.00323.xopenalex-snapshot
Mitochondrial DNA deletions induce the adenosine monophosphate‐activated protein kinase energy stress pathway and result in decreased secretion of some proteins
inferredcites →https://doi.org/10.1126/science.1147949openalex-snapshot
Life with Oxygen
inferredcites →https://doi.org/10.1126/science.1156906openalex-snapshot
ROS-Generating Mitochondrial DNA Mutations Can Regulate Tumor Cell Metastasis
inferredcites →https://doi.org/10.1126/science.1160809openalex-snapshot
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
inferredcites →https://doi.org/10.1126/science.1193494openalex-snapshot
The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
inferredcites →https://doi.org/10.1126/science.1211485openalex-snapshot
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
inferredcites →https://doi.org/10.1126/science.123.3191.309openalex-snapshot
On the Origin of Cancer Cells
inferredcites →https://doi.org/10.1146/annurev.cb.07.110191.002321openalex-snapshot
Replication and Transcription of Vertebrate Mitochondrial DNA
inferredcites →https://doi.org/10.1152/ajpcell.00247.2006openalex-snapshot
Multiparameter metabolic analysis reveals a close link between attenuated mitochondrial bioenergetic function and enhanced glycolysis dependency in human tumor cells
inferredcites →https://doi.org/10.1158/0008-5472.can-08-1839openalex-snapshot
Hypoxia-Inducible Factor 1α Mediates Anoikis Resistance via Suppression of α5 Integrin
inferredcites →https://doi.org/10.1158/0008-5472.can-10-3320openalex-snapshot
HIF Induces Human Embryonic Stem Cell Markers in Cancer Cells
inferredcites →https://doi.org/10.1158/1078-0432.ccr-09-0889openalex-snapshot
MYC-Induced Cancer Cell Energy Metabolism and Therapeutic Opportunities
inferredcites →https://doi.org/10.1159/000355050openalex-snapshot
Mitochondrial Function in Pluripotent Stem Cells and Cellular Reprogramming
inferredcites →https://doi.org/10.1186/jbiol61openalex-snapshot
Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
inferredcites →https://doi.org/10.1242/jcs.072272openalex-snapshot
A reduction in ATP demand and mitochondrial activity with neural differentiation of human embryonic stem cells
inferredcites →https://doi.org/10.1371/journal.pone.0012295openalex-snapshot
Mitochondrial DNA Variant Discovery and Evaluation in Human Cardiomyopathies through Next-Generation Sequencing
inferredcites →https://doi.org/10.1371/journal.pone.0013703openalex-snapshot
The LARGE Principle of Cellular Reprogramming: Lost, Acquired and Retained Gene Expression in Foreskin and Amniotic Fluid-Derived Human iPS Cells
inferredcites →https://doi.org/10.1371/journal.pone.0014095openalex-snapshot
Mitochondrial Rejuvenation After Induced Pluripotency
inferredcites →https://doi.org/10.1371/journal.pone.0017557openalex-snapshot
Efficient Feeder-Free Episomal Reprogramming with Small Molecules
inferredcites →https://doi.org/10.1371/journal.pone.0019601openalex-snapshot
Benchmarking of Mutation Diagnostics in Clinical Lung Cancer Specimens
inferredcites →https://doi.org/10.1371/journal.pone.0020914openalex-snapshot
Energy Metabolism in Human Pluripotent Stem Cells and Their Differentiated Counterparts
inferredcites →https://doi.org/10.1371/journal.pone.0024351openalex-snapshot
Molecular Insights into Reprogramming-Initiation Events Mediated by the OSKM Gene Regulatory Network
inferredcites →https://doi.org/10.1371/journal.pone.0027352openalex-snapshot
Mitochondrial-Associated Cell Death Mechanisms Are Reset to an Embryonic-Like State in Aged Donor-Derived iPS Cells Harboring Chromosomal Aberrations
inferredcites →https://doi.org/10.1371/journal.pone.0030714openalex-snapshot
UCP2 Inhibits ROS-Mediated Apoptosis in A549 under Hypoxic Conditions
inferredcites →https://doi.org/10.1385/1-59259-284-8:129openalex-snapshot
Reproducible Quantitative PCR of Mitochondrial and Nuclear DNA Copy Number Using the LightCycler™
inferredcites →https://doi.org/10.1387/ijdb.103198apopenalex-snapshot
Modulation of mitochondrial biogenesis and bioenergetic metabolism upon in vitro and in vivo differentiation of human ES and iPS cells
inferredcites →https://doi.org/10.1530/rep-09-0300openalex-snapshot
Hypoxia inducible factors regulate pluripotency and proliferation in human embryonic stem cells cultured at reduced oxygen tensions
inferredcites →https://doi.org/10.18632/oncotarget.278openalex-snapshot
No evidence for a shift in pyruvate kinase PKM1 to PKM2 expression during tumorigenesis

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Coptisine Improves Anxiety-Like Behaviors by Regulating the Warburg Effect in Microglia Via Pkm2
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A PD‐L1 Antibody‐Conjugated PAMAM Dendrimer Nanosystem for Simultaneously Inhibiting Glycolysis and Promoting Immune Response in Fighting Breast Cancer
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Nanomaterials‐mediated glycolysis rewriting to potentiate tumor immunotherapy
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SIRT3 elicited an anti‐Warburg effect through HIF1α/PDK1/PDHA1 to inhibit cholangiocarcinoma tumorigenesis
inferred← citeshttps://doi.org/10.1002/cbin.11212openalex-snapshot
Up‐regulation of the pentose phosphate pathway and HIF‐1α expression during neural progenitor cell induction following glutamate treatment in rat ex vivo retina
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Micro‐environment and intracellular metabolism modulation of adipose tissue macrophage polarization in relation to chronic inflammatory diseases
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Copy number profiling of adult relapsed B‐cell precursor acute lymphoblastic leukemia reveals potential leukemia progression mechanisms
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New strategies for targeting glucose metabolism–mediated acidosis for colorectal cancer therapy
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Chemical simulation of hypoxia in donor cells improves development of somatic cell nuclear transfer‐derived embryos and increases abundance of transcripts related to glycolysis
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Regulation of Mitochondrial Function and Cellular Energy Metabolism by Protein Kinase C-λ/ι: A Novel Mode of Balancing Pluripotency
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Concise Review: Induced Pluripotency by Defined Factors: Prey of Oxidative Stress
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Core Pluripotency Factors Directly Regulate Metabolism in Embryonic Stem Cell to Maintain Pluripotency
inferred← citeshttps://doi.org/10.1002/stem.2209openalex-snapshot
Srebp-1 Interacts with c-Myc to Enhance Somatic Cell Reprogramming
inferred← citeshttps://doi.org/10.1002/stem.2510openalex-snapshot
Metabolic Reconfiguration Supports Reacquisition of Primitive Phenotype in Human Mesenchymal Stem Cell Aggregates
inferred← citeshttps://doi.org/10.1002/stem.2637openalex-snapshot
Concise Review: Induced Pluripotent Stem Cell-Based Drug Discovery for Mitochondrial Disease
inferred← citeshttps://doi.org/10.1002/stem.3029openalex-snapshot
Metabolomic and Transcriptional Analyses Reveal Atmospheric Oxygen During Human Induced Pluripotent Stem Cell Generation Impairs Metabolic Reprogramming
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Mitochondrial Inheritance Following Nuclear Transfer: From Cloned Animals to Patients with Mitochondrial Disease
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Assessing the Bioenergetic Profile of Human Pluripotent Stem Cells
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The Warburg Effect and Aerobic Glycolysis in Tumors
inferred← citeshttps://doi.org/10.1007/978-3-319-07320-0_10openalex-snapshot
Energy Metabolism and Metabolic Sensors in Stem Cells: The Metabostem Crossroads of Aging and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-55330-6_30openalex-snapshot
Mitochondrial Heteroplasmy
inferred← citeshttps://doi.org/10.1007/978-3-319-90695-9_12openalex-snapshot
Stem Cells and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-7091-1824-5_14openalex-snapshot
Metabolic Fluxes in Cancer Metabolism
inferred← citeshttps://doi.org/10.1007/s00018-015-1834-1openalex-snapshot
Metabolic restructuring and cell fate conversion
inferred← citeshttps://doi.org/10.1007/s00018-020-03727-0openalex-snapshot
Hypoxia-induced alternative splicing in human diseases: the pledge, the turn, and the prestige
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Mitochondrial function in spinal cord injury and regeneration
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AMPK and HIF signaling pathways regulate both longevity and cancer growth: the good news and the bad news about survival mechanisms
inferred← citeshttps://doi.org/10.1007/s10522-023-10018-1openalex-snapshot
Insights on the role of l-lactate as a signaling molecule in skin aging
inferred← citeshttps://doi.org/10.1007/s11427-021-2039-6openalex-snapshot
Individual variation in buffalo somatic cell cloning efficiency is related to glycolytic metabolism
inferred← citeshttps://doi.org/10.1007/s11515-016-1417-zopenalex-snapshot
Metabolism of pluripotent stem cells
inferred← citeshttps://doi.org/10.1007/s11596-020-2198-9openalex-snapshot
Vascular Metabolic Mechanisms of Pulmonary Hypertension
inferred← citeshttps://doi.org/10.1007/s12011-023-03706-zopenalex-snapshot
ERK/PKM2 Is Mediated in the Warburg Effect and Cell Proliferation in Arsenic-Induced Human L-02 Hepatocytes
inferred← citeshttps://doi.org/10.1007/s12015-017-9782-9openalex-snapshot
Noncoding RNAs in the Regulation of Pluripotency and Reprogramming
inferred← citeshttps://doi.org/10.1007/s12015-021-10294-9openalex-snapshot
Dual-specificity Tyrosine Phosphorylation-regulated Kinase Inhibitor ID-8 Promotes Human Somatic Cell Reprogramming by Activating PDK4 Expression
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The Role of Endoplasmic Reticulum and Mitochondria in Maintaining Redox Status and Glycolytic Metabolism in Pluripotent Stem Cells
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Cerulenin suppresses ErbB2-overexpressing breast cancer by targeting ErbB2/PKM2 pathway
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Revisiting Mitochondrial Function and Metabolism in Pluripotent Stem Cells: Where Do We Stand in Neurological Diseases?
inferred← citeshttps://doi.org/10.1007/s12035-020-02274-wopenalex-snapshot
Müller Glia-Mediated Retinal Regeneration
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Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogramming
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Uncovering the important role of mitochondrial dynamics in oogenesis: impact on fertility and metabolic disorder transmission
inferred← citeshttps://doi.org/10.1007/s40778-017-0071-yopenalex-snapshot
Transcriptional Regulation of Stem Cell and Cancer Stem Cell Metabolism
inferred← citeshttps://doi.org/10.1007/s40778-018-0127-7openalex-snapshot
Hypoxia Signaling Pathway in Stem Cell Regulation: Good and Evil
inferred← citeshttps://doi.org/10.1007/s40778-024-00236-9openalex-snapshot
RNA-Mediated Regulation of Glycolysis in Embryonic Stem Cell Pluripotency and Differentiation
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Hypoxia Regulation of Stem Cell
inferred← citeshttps://doi.org/10.1016/b978-0-12-814879-2.00007-8openalex-snapshot
Somatic Cell Epigenetic Reprogramming: Molecular Mechanisms and Therapeutic Potential
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Current reprogramming methods to generate high-quality iPSCs
inferred← citeshttps://doi.org/10.1016/b978-0-323-90059-1.00007-5openalex-snapshot
Auxiliary pluripotency-associated genes and their contributions in the generation of induced pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/b978-0-323-99892-5.00008-6openalex-snapshot
Proteomic approach for creation of the protein marker panels to control the quality of human induced pluripotent stem cells
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2020.02.003openalex-snapshot
Epigenetic metabolites license stem cell states
inferred← citeshttps://doi.org/10.1016/j.arr.2022.101667openalex-snapshot
Mitochondrial function and dynamics in neural stem cells and neurogenesis: Implications for neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.01.009openalex-snapshot
Mitochondrial resetting and metabolic reprogramming in induced pluripotent stem cells and mitochondrial disease modeling
inferred← citeshttps://doi.org/10.1016/j.bbagen.2016.09.008openalex-snapshot
Sirtuins in metabolism, stemness and differentiation
inferred← citeshttps://doi.org/10.1016/j.bbcan.2014.07.008openalex-snapshot
The multifaceted regulation and functions of PKM2 in tumor progression
inferred← citeshttps://doi.org/10.1016/j.bbcan.2018.10.006openalex-snapshot
Unraveling the journey of cancer stem cells from origin to metastasis
inferred← citeshttps://doi.org/10.1016/j.bbcan.2021.188568openalex-snapshot
Targeting pyruvate dehydrogenase kinase signaling in the development of effective cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbrc.2026.153488openalex-snapshot
Hypoxia-induced LGALS8-AS1 sustains oxidative phosphorylation to drive breast cancer progression
inferred← citeshttps://doi.org/10.1016/j.bcp.2014.07.019openalex-snapshot
Heterogeneity of glycolysis in cancers and therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.bcp.2025.117560openalex-snapshot
Immunometabolic control of ILC3s: implications for epithelial barrier homeostasis and inflammation
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.118150openalex-snapshot
Bufalin inhibits proliferation of non-small cell lung cancer by promoting metabolic reprogramming through inhibition of pyruvate kinase M2
inferred← citeshttps://doi.org/10.1016/j.canlet.2020.11.018openalex-snapshot
Pyruvate kinase M2 (PKM2) in cancer and cancer therapeutics
inferred← citeshttps://doi.org/10.1016/j.ceb.2017.12.004openalex-snapshot
Mitochondrial metabolism in early neural fate and its relevance for neuronal disease modeling
inferred← citeshttps://doi.org/10.1016/j.cellsig.2015.02.030openalex-snapshot
GRP78 is implicated in the modulation of tumor aerobic glycolysis by promoting autophagic degradation of IKKβ
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.02.003openalex-snapshot
NRF2 Orchestrates the Metabolic Shift during Induced Pluripotent Stem Cell Reprogramming
inferred← citeshttps://doi.org/10.1016/j.celrep.2020.107538openalex-snapshot
m.3243A > G-Induced Mitochondrial Dysfunction Impairs Human Neuronal Development and Reduces Neuronal Network Activity and Synchronicity
inferred← citeshttps://doi.org/10.1016/j.cmet.2018.11.007openalex-snapshot
Mitochondrial Dynamics Is Critical for the Full Pluripotency and Embryonic Developmental Potential of Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.devcel.2021.03.007openalex-snapshot
BCKDK regulates the TCA cycle through PDC in the absence of PDK family during embryonic development
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.117341openalex-snapshot
Hexavalent chromium induced metabolic reprogramming, carcinogenesis and tumor progression through PDK1 upregulation
inferred← citeshttps://doi.org/10.1016/j.exger.2020.110870openalex-snapshot
Mitochondrial dynamics and metabolism in induced pluripotency
inferred← citeshttps://doi.org/10.1016/j.gde.2016.05.004openalex-snapshot
Mitochondrial functions in stem cells
inferred← citeshttps://doi.org/10.1016/j.gde.2017.06.008openalex-snapshot
Metabolic switching and cell fate decisions: implications for pluripotency, reprogramming and development
inferred← citeshttps://doi.org/10.1016/j.gene.2025.149978openalex-snapshot
PRDM14 promotes the bovine somatic stem cell reprogramming through enhancing oxidative phosphorylation at the initial stage
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.10.213openalex-snapshot
A review on the emerging roles of pyruvate kinase M2 in anti-leukemia therapy
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111791openalex-snapshot
Dexamethasone protects against asthma via regulating Hif-1α-glycolysis-lactate axis and protein lactylation
inferred← citeshttps://doi.org/10.1016/j.jbc.2025.110344openalex-snapshot
The stage-specific roles of HIF-1α in regulating mESC pluripotency during oxygen transition
inferred← citeshttps://doi.org/10.1016/j.jprot.2016.10.002openalex-snapshot
Proteomic analysis of pancreatic cancer stem cells: Functional role of fatty acid synthesis and mevalonate pathways
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.118796openalex-snapshot
Shikonin differentially regulates glucose metabolism via PKM2 and HIF1α to overcome apoptosis in a refractory HCC cell line
inferred← citeshttps://doi.org/10.1016/j.mad.2018.05.009openalex-snapshot
Role of human oocyte-enriched factors in somatic cell reprograming
inferred← citeshttps://doi.org/10.1016/j.mito.2020.10.002openalex-snapshot
Stem cell plasticity and regenerative potential regulation through Ca2+-mediated mitochondrial nuclear crosstalk
inferred← citeshttps://doi.org/10.1016/j.mito.2023.02.007openalex-snapshot
The pyruvate dehydrogenase complex: Life’s essential, vulnerable and druggable energy homeostat
inferred← citeshttps://doi.org/10.1016/j.neuint.2017.06.007openalex-snapshot
Mitochondria/metabolic reprogramming in the formation of neurons from peripheral cells: Cause or consequence and the implications to their utility
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2024.06.021openalex-snapshot
Unraveling the Triad: Hypoxia, Oxidative Stress and Inflammation in Neurodegenerative Disorders
inferred← citeshttps://doi.org/10.1016/j.redox.2019.101197openalex-snapshot
Ku80 promotes melanoma growth and regulates antitumor effect of melatonin by targeting HIF1-α dependent PDK-1 signaling pathway
inferred← citeshttps://doi.org/10.1016/j.scr.2015.10.013openalex-snapshot
Generation of iPSC lines from a Nijmegen Breakage Syndrome patient
inferred← citeshttps://doi.org/10.1016/j.scr.2018.05.005openalex-snapshot
Metabolic plasticity during transition to naïve-like pluripotency in canine embryo-derived stem cells
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.02.004openalex-snapshot
Metabolic remodeling in early development and cardiomyocyte maturation
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.02.010openalex-snapshot
Energy metabolism in the acquisition and maintenance of stemness
inferred← citeshttps://doi.org/10.1016/j.semcdb.2016.02.018openalex-snapshot
Energy metabolism in neuronal/glial induction and in iPSC models of brain disorders
inferred← citeshttps://doi.org/10.1016/j.stem.2014.02.012openalex-snapshot
Hypoxia-Inducible Factors Have Distinct and Stage-Specific Roles during Reprogramming of Human Cells to Pluripotency
inferred← citeshttps://doi.org/10.1016/j.stem.2015.11.012openalex-snapshot
Metabolic Reprogramming of Stem Cell Epigenetics
inferred← citeshttps://doi.org/10.1016/j.stem.2016.09.005openalex-snapshot
A Glycolytic Solution for Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1016/j.stem.2016.12.013openalex-snapshot
Human iPSC-Derived Neural Progenitors Are an Effective Drug Discovery Model for Neurological mtDNA Disorders
inferred← citeshttps://doi.org/10.1016/j.stem.2017.03.010openalex-snapshot
Aberrant DNA Methylation in Human iPSCs Associates with MYC-Binding Motifs in a Clone-Specific Manner Independent of Genetics
inferred← citeshttps://doi.org/10.1016/j.stemcr.2017.01.026openalex-snapshot
A Role for KLF4 in Promoting the Metabolic Shift via TCL1 during Induced Pluripotent Stem Cell Generation
inferred← citeshttps://doi.org/10.1016/j.stemcr.2020.01.006openalex-snapshot
HIF1α Regulates Early Metabolic Changes due to Activation of Innate Immunity in Nuclear Reprogramming
inferred← citeshttps://doi.org/10.1016/j.stemcr.2020.06.018openalex-snapshot
Mthfd2 Modulates Mitochondrial Function and DNA Repair to Maintain the Pluripotency of Mouse Stem Cells
inferred← citeshttps://doi.org/10.1016/j.tcb.2015.12.003openalex-snapshot
Transcriptional Control of Somatic Cell Reprogramming
inferred← citeshttps://doi.org/10.1016/j.tcb.2018.09.005openalex-snapshot
Metabolic and Mechanical Cues Regulating Pluripotent Stem Cell Fate
inferred← citeshttps://doi.org/10.1016/j.tcb.2020.12.009openalex-snapshot
Mitochondrial DNA Dynamics in Reprogramming to Pluripotency
inferred← citeshttps://doi.org/10.1016/j.tips.2017.05.002openalex-snapshot
Reprogramming of the Tumor in the Hypoxic Niche: The Emerging Concept and Associated Therapeutic Strategies
inferred← citeshttps://doi.org/10.1016/j.tiv.2019.03.016openalex-snapshot
Ochratoxin A upregulates biomarkers associated with hypoxia and transformation in human kidney cells
inferred← citeshttps://doi.org/10.1016/j.ymben.2019.02.003openalex-snapshot
Glycine decarboxylase regulates the maintenance and induction of pluripotency via metabolic control
inferred← citeshttps://doi.org/10.1021/acs.analchem.9b05738openalex-snapshot
Microfluidic Platform for the Isolation of Cancer-Cell Subpopulations Based on Single-Cell Glycolysis
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.1c00981openalex-snapshot
A Perspective on Medicinal Chemistry Approaches for Targeting Pyruvate Kinase M2
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.3c01512openalex-snapshot
Mechanistic Investigation of Thiazole-Based Pyruvate Kinase M2 Inhibitor Causing Tumor Regression in Triple-Negative Breast Cancer
inferred← citeshttps://doi.org/10.1021/acssensors.3c00106openalex-snapshot
Molecular Beacon Imaging System to Discriminate the Differentiation State of Cells from Energy Metabolic Pathways
inferred← citeshttps://doi.org/10.1038/cdd.2015.43openalex-snapshot
Mitofusins deficiency elicits mitochondrial metabolic reprogramming to pluripotency
inferred← citeshttps://doi.org/10.1038/ncb3517openalex-snapshot
Metabolic control of primed human pluripotent stem cell fate and function by the miR-200c–SIRT2 axis
inferred← citeshttps://doi.org/10.1038/ng.3615openalex-snapshot
Genomic analysis of snub-nosed monkeys (Rhinopithecus) identifies genes and processes related to high-altitude adaptation
inferred← citeshttps://doi.org/10.1038/onc.2017.368openalex-snapshot
Glycolysis gatekeeper PDK1 reprograms breast cancer stem cells under hypoxia
inferred← citeshttps://doi.org/10.1038/s12276-021-00672-1openalex-snapshot
Pyruvate dehydrogenase kinase 1 and 2 deficiency reduces high-fat diet-induced hypertrophic obesity and inhibits the differentiation of preadipocytes into mature adipocytes
inferred← citeshttps://doi.org/10.1038/s12276-021-00713-9openalex-snapshot
The impact of fine particulate matter (PM) on various beneficial functions of human endometrial stem cells through its key regulator SERPINB2
inferred← citeshttps://doi.org/10.1038/s12276-025-01476-3openalex-snapshot
Changes in mitochondrial thymidine metabolism and mtDNA copy number during induced pluripotency
inferred← citeshttps://doi.org/10.1038/s41467-023-42093-wopenalex-snapshot
Positive regulation of oxidative phosphorylation by nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
inferred← citeshttps://doi.org/10.1038/s41467-024-45167-5openalex-snapshot
Activation of GPR3-β-arrestin2-PKM2 pathway in Kupffer cells stimulates glycolysis and inhibits obesity and liver pathogenesis
inferred← citeshttps://doi.org/10.1038/s41598-017-07905-2openalex-snapshot
Nijmegen Breakage Syndrome fibroblasts and iPSCs: cellular models for uncovering disease-associated signaling pathways and establishing a screening platform for anti-oxidants
inferred← citeshttps://doi.org/10.1038/s41598-020-65193-9openalex-snapshot
Lactate preconditioning promotes a HIF-1α-mediated metabolic shift from OXPHOS to glycolysis in normal human diploid fibroblasts
inferred← citeshttps://doi.org/10.1038/s41598-022-13191-4openalex-snapshot
Reconstruction of functional human epidermis equivalent containing 5%IPS-derived keratinocytes treated with mitochondrial stimulating plant extracts
inferred← citeshttps://doi.org/10.1038/s42003-021-02073-6openalex-snapshot
Mitofusin-2 boosts innate immunity through the maintenance of aerobic glycolysis and activation of xenophagy in mice
inferred← citeshttps://doi.org/10.1038/srep17500openalex-snapshot
GLUT3 and PKM2 regulate OCT4 expression and support the hypoxic culture of human embryonic stem cells
inferred← citeshttps://doi.org/10.1038/srep30903openalex-snapshot
Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch
inferred← citeshttps://doi.org/10.1073/pnas.1620915114openalex-snapshot
Distinct requirements for energy metabolism in mouse primordial germ cells and their reprogramming to embryonic germ cells
inferred← citeshttps://doi.org/10.1074/jbc.tm117.000832openalex-snapshot
Metabolism in pluripotency: Both driver and passenger?
inferred← citeshttps://doi.org/10.1074/jbc.tm118.000831openalex-snapshot
The role of α-ketoglutarate–dependent proteins in pluripotency acquisition and maintenance
inferred← citeshttps://doi.org/10.1080/15384101.2015.1022697openalex-snapshot
Metabolic control of cancer cell stemness: Lessons from iPS cells
inferred← citeshttps://doi.org/10.1080/15384101.2019.1672465openalex-snapshot
The TCL1 function revisited focusing on metabolic requirements of stemness
inferred← citeshttps://doi.org/10.1080/21505594.2021.1965829openalex-snapshot
Mitofusin 2, a key coordinator between mitochondrial dynamics and innate immunity
inferred← citeshttps://doi.org/10.1089/ars.2017.7217openalex-snapshot
Hallmarks of Pulmonary Hypertension: Mesenchymal and Inflammatory Cell Metabolic Reprogramming
inferred← citeshttps://doi.org/10.1089/ars.2017.7241openalex-snapshot
Pluripotency Transcription Factors and Metabolic Reprogramming of Mitochondria in Tumor-Initiating Stem-like Cells
inferred← citeshttps://doi.org/10.1089/ars.2019.7983openalex-snapshot
Redox and Epigenetics in Human Pluripotent Stem Cells Differentiation
inferred← citeshttps://doi.org/10.1089/cell.2015.0051openalex-snapshot
Hypoxia Enhances Direct Reprogramming of Mouse Fibroblasts to Cardiomyocyte-Like Cells
inferred← citeshttps://doi.org/10.1089/dna.2014.2375openalex-snapshot
Atypical Cell Populations Associated with Acquired Resistance to Cytostatics and Cancer Stem Cell Features: The Role of Mitochondria in Nuclear Encapsulation
inferred← citeshttps://doi.org/10.1089/scd.2014.0059openalex-snapshot
Drp1 Is Dispensable for Mitochondria Biogenesis in Induction to Pluripotency but Required for Differentiation of Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1089/scd.2015.0117openalex-snapshot
Connecting Mitochondria, Metabolism, and Stem Cell Fate
inferred← citeshttps://doi.org/10.1089/scd.2017.0066openalex-snapshot
Roles of Diffusion Dynamics in Stem Cell Signaling and Three-Dimensional Tissue Development
inferred← citeshttps://doi.org/10.1089/scd.2021.0347openalex-snapshot
Modulation of PKM1/2 Levels by Steric Blocking Morpholinos Alters the Metabolic and Pluripotent State of Murine Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.1093/jnci/djx071openalex-snapshot
Therapeutic Targeting of the Pyruvate Dehydrogenase Complex/Pyruvate Dehydrogenase Kinase (PDC/PDK) Axis in Cancer
inferred← citeshttps://doi.org/10.1093/stmcls/sxaf050openalex-snapshot
Neuronal branching in stem cell models of mitochondrial and neurological diseases
inferred← citeshttps://doi.org/10.1096/fj.201902829rropenalex-snapshot
HIF‐1α/Actl6a/H3K9ac axis is critical for pluripotency and lineage differentiation of human induced pluripotent stem cells
inferred← citeshttps://doi.org/10.1097/md.0000000000008690openalex-snapshot
Prognostic significance of metabolic enzyme pyruvate kinase M2 in breast cancer
inferred← citeshttps://doi.org/10.1097/md.0000000000044295openalex-snapshot
Advances in the therapeutic applications of dichloroacetate as a metabolic regulator: A review
inferred← citeshttps://doi.org/10.1098/rstb.2017.0213openalex-snapshot
Pluripotent stem cells: induction and self-renewal
inferred← citeshttps://doi.org/10.1101/2022.06.26.497645openalex-snapshot
Is the Naked mole-rat a domestic animal?
inferred← citeshttps://doi.org/10.1101/2022.06.30.498328openalex-snapshot
Regulation of oxidative phosphorylation by Nuclear myosin 1 protects cells from metabolic reprogramming and tumorigenesis in mice
inferred← citeshttps://doi.org/10.1111/apm.13378openalex-snapshot
Metabolic drives affecting Th17/Treg gene expression changes and differentiation: impact on immune‐microenvironment regulation
inferred← citeshttps://doi.org/10.1111/brv.12140openalex-snapshot
The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
inferred← citeshttps://doi.org/10.1111/febs.16740openalex-snapshot
PKM2 controls the translation of TFE3 to maintain the integrity of the Golgi apparatus for the survival of HeLa and ME ‐180 cervical cancer cells
inferred← citeshttps://doi.org/10.1111/jre.12941openalex-snapshot
Abnormal mitochondrial structure and function are retained in gingival tissues and human gingival fibroblasts from patients with chronic periodontitis
inferred← citeshttps://doi.org/10.1111/wrr.13050openalex-snapshot
Aerobic glycolysis is important for zebrafish larval wound closure and tail regeneration
inferred← citeshttps://doi.org/10.1152/physrev.00026.2020openalex-snapshot
Regulation and metabolic functions of mTORC1 and mTORC2
inferred← citeshttps://doi.org/10.1155/2017/4745252openalex-snapshot
Metabolic Reprogramming, Autophagy, and Reactive Oxygen Species Are Necessary for Primordial Germ Cell Reprogramming into Pluripotency
inferred← citeshttps://doi.org/10.1155/2019/7360121openalex-snapshot
Metabolism Is a Key Regulator of Induced Pluripotent Stem Cell Reprogramming
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-18-3533openalex-snapshot
LIMS1 Promotes Pancreatic Cancer Cell Survival under Oxygen–Glucose Deprivation Conditions by Enhancing HIF1A Protein Translation
inferred← citeshttps://doi.org/10.1159/000355050openalex-snapshot
Mitochondrial Function in Pluripotent Stem Cells and Cellular Reprogramming
inferred← citeshttps://doi.org/10.1161/circresaha.120.316443openalex-snapshot
Epigenetic Metabolic Reprogramming of Right Ventricular Fibroblasts in Pulmonary Arterial Hypertension
inferred← citeshttps://doi.org/10.1165/rcmb.2016-0186ocopenalex-snapshot
Targeting Hypoxia-Inducible Factor-1α/Pyruvate Dehydrogenase Kinase 1 Axis by Dichloroacetate Suppresses Bleomycin-induced Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1182/bloodadvances.2019000375openalex-snapshot
Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche
inferred← citeshttps://doi.org/10.1186/2045-9769-3-5openalex-snapshot
A mitochondrial strategy for safeguarding the reprogrammed genome
inferred← citeshttps://doi.org/10.1186/s12974-022-02686-6openalex-snapshot
Teriflunomide as a therapeutic means for myelin repair
inferred← citeshttps://doi.org/10.1186/s13046-016-0446-4openalex-snapshot
Leptin promotes epithelial-mesenchymal transition of breast cancer via the upregulation of pyruvate kinase M2
inferred← citeshttps://doi.org/10.1186/s13046-021-02035-0openalex-snapshot
Cellular senescence or stemness: hypoxia flips the coin
inferred← citeshttps://doi.org/10.1186/s13046-025-03501-9openalex-snapshot
Tfcp2l1 as a central integrator of hypoxia, dedifferentiation, and tumor progression
inferred← citeshttps://doi.org/10.1186/s13046-026-03694-7openalex-snapshot
Human iPSC-derived and conventional cancer models in precision oncology: advancing patient-specific therapies from bench to bedside
inferred← citeshttps://doi.org/10.1186/s13578-017-0166-2openalex-snapshot
The miR-290-295 cluster as multi-faceted players in mouse embryonic stem cells
inferred← citeshttps://doi.org/10.1186/s13578-019-0317-8openalex-snapshot
PKM2, function and expression and regulation
inferred← citeshttps://doi.org/10.1186/s13578-023-01160-xopenalex-snapshot
Unraveling the 2,3-diketo-l-gulonic acid-dependent and -independent impacts of l-ascorbic acid on somatic cell reprogramming
inferred← citeshttps://doi.org/10.1186/s40170-020-00216-7openalex-snapshot
Fine-tuning the metabolic rewiring and adaptation of translational machinery during an epithelial-mesenchymal transition in breast cancer cells
inferred← citeshttps://doi.org/10.1186/s41232-020-00117-8openalex-snapshot
Metabolic remodeling during somatic cell reprogramming to induced pluripotent stem cells: involvement of hypoxia-inducible factor 1
inferred← citeshttps://doi.org/10.1186/s41232-021-00156-9openalex-snapshot
Metabolism of human pluripotent stem cells and differentiated cells for regenerative therapy: a focus on cardiomyocytes
inferred← citeshttps://doi.org/10.1242/dev.128389openalex-snapshot
Metabolic remodeling during the loss and acquisition of pluripotency
inferred← citeshttps://doi.org/10.1242/dev.143420openalex-snapshot
The role of mitochondria in stem cell fate and aging
inferred← citeshttps://doi.org/10.1242/dmm.052585openalex-snapshot
Induced pluripotent stem cells from a transgenic minipig model of Huntington's disease reveal early metabolic changes
inferred← citeshttps://doi.org/10.1247/csf.18018openalex-snapshot
An Anti-tumorigenic Role of the Warburg Effect at Emergence of Transformed Cells
inferred← citeshttps://doi.org/10.12659/msm.902515openalex-snapshot
Aging Reversal and Healthy Longevity is in Reach: Dependence on Mitochondrial DNA Heteroplasmy as a Key Molecular Target
inferred← citeshttps://doi.org/10.1371/journal.pone.0131663openalex-snapshot
Dichloroacetate, the Pyruvate Dehydrogenase Complex and the Modulation of mESC Pluripotency
inferred← citeshttps://doi.org/10.1371/journal.pone.0132789openalex-snapshot
Embryonic MicroRNA-369 Controls Metabolic Splicing Factors and Urges Cellular Reprograming
inferred← citeshttps://doi.org/10.1371/journal.pone.0135617openalex-snapshot
Differentiate or Die: 3-Bromopyruvate and Pluripotency in Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0136927openalex-snapshot
Different Blood Cell-Derived Transcriptome Signatures in Cows Exposed to Vaccination Pre- or Postpartum
inferred← citeshttps://doi.org/10.1371/journal.pone.0154309openalex-snapshot
Hypoxia Inducible Factor 1 Alpha Is Expressed in Germ Cells throughout the Murine Life Cycle
inferred← citeshttps://doi.org/10.1371/journal.pone.0171714openalex-snapshot
Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function
inferred← citeshttps://doi.org/10.1371/journal.pone.0232759openalex-snapshot
Human-stimulated oocyte extract induces genetic and mitochondrial reprogramming of mesenchymal stromal cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0252282openalex-snapshot
A Warburg-like metabolic program coordinates Wnt, AMPK, and mTOR signaling pathways in epileptogenesis
inferred← citeshttps://doi.org/10.1523/jneurosci.2006-14.2016openalex-snapshot
Histone Deacetylase Inhibitors Protect Against Pyruvate Dehydrogenase Dysfunction in Huntington's Disease
inferred← citeshttps://doi.org/10.15252/embj.201490441openalex-snapshot
miR‐290/371‐Mbd2‐Myc circuit regulates glycolytic metabolism to promote pluripotency
inferred← citeshttps://doi.org/10.15252/embj.201490446openalex-snapshot
Pluripotent stem cell energy metabolism: an update
inferred← citeshttps://doi.org/10.15252/embj.201695417openalex-snapshot
Fatty acid synthesis is critical for stem cell pluripotency via promoting mitochondrial fission
inferred← citeshttps://doi.org/10.15252/embj.2019102961openalex-snapshot
Metabolic switch and epithelial–mesenchymal transition cooperate to regulate pluripotency
inferred← citeshttps://doi.org/10.15252/embr.201745432openalex-snapshot
Mitochondria and the dynamic control of stem cell homeostasis
inferred← citeshttps://doi.org/10.15252/msb.20167386openalex-snapshot
Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer
inferred← citeshttps://doi.org/10.15302/j-fase-2014004openalex-snapshot
Fabrication of cellulose aerogel from wheat straw with strong absorptive capacity
inferred← citeshttps://doi.org/10.15302/j-fase-2014009openalex-snapshot
Progress, problems and prospects of porcine pluripotent stem cells
inferred← citeshttps://doi.org/10.18632/oncotarget.13717openalex-snapshot
Mitochondrial pyruvate carrier function is negatively linked to Warburg phenotype in vitro and malignant features in esophageal squamous cell carcinomas
inferred← citeshttps://doi.org/10.18632/oncotarget.14093openalex-snapshot
Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism
inferred← citeshttps://doi.org/10.18632/oncotarget.20685openalex-snapshot
Pkm2 can enhance pluripotency in ESCs and promote somatic cell reprogramming to iPSCs
inferred← citeshttps://doi.org/10.20944/preprints202405.0923.v1openalex-snapshot
Energy Metabolism Pathways in Stem Cell Fate Regulation
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3234985/v1openalex-snapshot
Bawei Chenxiang Wan ameliorates right ventricular hypertrophy in rats with high altitude heart disease by SIRT3-HIF1α-PDK/PDH signaling pathway improving fatty acid and glucose metabolism
inferred← citeshttps://doi.org/10.21203/rs.3.rs-820071/v1openalex-snapshot
An Efficient Chemical-Defined Condition for Generation of Human Induced Pluripotent Stem Cells
inferred← citeshttps://doi.org/10.2147/ott.s253137openalex-snapshot
Phosphoribosyl Pyrophosphate Amidotransferase Promotes the Progression of Thyroid Cancer via Regulating Pyruvate Kinase M2
inferred← citeshttps://doi.org/10.2174/1574888x15666200512105347openalex-snapshot
Metabolic Regulation and Related Molecular Mechanisms in Various Stem Cell Functions
inferred← citeshttps://doi.org/10.2217/cns.14.13openalex-snapshot
PDK1: A New Therapeutic Target for Glioblastoma?
inferred← citeshttps://doi.org/10.26508/lsa.201900413openalex-snapshot
Glycine cleavage system determines the fate of pluripotent stem cells via the regulation of senescence and epigenetic modifications
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