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Discovery pharmaceutics—Challenges and opportunities
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/1520-6017(200103)90:3<253::aid-jps1>3.0.co;2-wopenalex-snapshot
Oxidative degradation of pharmaceuticals: Theory, mechanisms and inhibition
inferredcites →https://doi.org/10.1002/1522-2683()22:6<1112::aid-elps1112>3.0.co;2-1openalex-snapshot
Medium-throughput pKa screening of pharmaceuticals by pressure-assisted capillary electrophoresis
inferredcites →https://doi.org/10.1002/9783906390437.ch17openalex-snapshot
Lipophilicity Profiles: Theory and Measurement
inferredcites →https://doi.org/10.1002/9783906390437.ch21openalex-snapshot
Recent Advances in Reversed‐Phase‐HPLC Techniques to Determine Lipophilicity
inferredcites →https://doi.org/10.1002/jps.10055openalex-snapshot
An automated workstation for forced degradation of active pharmaceutical ingredients
inferredcites →https://doi.org/10.1002/jps.10366openalex-snapshot
General pharmaceutics—The new physical pharmacy
inferredcites →https://doi.org/10.1002/jps.10396openalex-snapshot
Prediction of Precipitation-Induced Phlebitis: A Statistical Validation of an In Vitro Model
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High throughput physicochemical profiling for drug discovery
inferredcites →https://doi.org/10.1002/jps.2600840427openalex-snapshot
Effect of pH on Injection Phlebitis
inferredcites →https://doi.org/10.1007/978-1-349-14416-7openalex-snapshot
Physicochemical Principles of Pharmacy
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Physicochemical Principles of Pharmacy
inferredcites →https://doi.org/10.1007/978-94-009-5548-6openalex-snapshot
The Determination of Ionization Constants
inferredcites →https://doi.org/10.1016/0731-7085(94)e0011-oopenalex-snapshot
Automated analytical systems for drug development studies. I — A system for the determination of drug stability
inferredcites →https://doi.org/10.1016/0731-7085(96)01843-2openalex-snapshot
Predictive strategy for the rapid structure elucidation of drug degradants
inferredcites →https://doi.org/10.1016/j.addr.2003.10.007openalex-snapshot
Impact of solid state properties on developability assessment of drug candidates
inferredcites →https://doi.org/10.1016/j.ijpharm.2003.10.003openalex-snapshot
New screening method for the determination of stability of pharmaceuticals
inferredcites →https://doi.org/10.1016/j.jpba.2004.08.008openalex-snapshot
ICH guidance in practice: establishment of inherent stability of secnidazole and development of a validated stability-indicating high-performance liquid chromatographic assay method
inferredcites →https://doi.org/10.1016/s0031-6997(25)00049-3openalex-snapshot
Cationic amphiphilic drugs and phospholipid storage disorder.
inferredcites →https://doi.org/10.1016/s0169-409x(00)00129-0openalex-snapshot
Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings 1PII of original article: S0169-409X(96)00423-1. The article was originally published in Advanced Drug Delivery Reviews 23 (1997) 3–25. 1
inferredcites →https://doi.org/10.1016/s0169-409x(01)00102-8openalex-snapshot
Chemical reactivity in solid-state pharmaceuticals: formulation implications
inferredcites →https://doi.org/10.1016/s0378-5173(01)00746-3openalex-snapshot
Formulation and stability testing of photolabile drugs
inferredcites →https://doi.org/10.1016/s0731-7085(02)00047-xopenalex-snapshot
Development of validated stability-indicating assay methods—critical review
inferredcites →https://doi.org/10.1016/s1367-5931(03)00055-3openalex-snapshot
Profiling drug-like properties in discovery research
inferredcites →https://doi.org/10.1021/ac9912247openalex-snapshot
A High-Throughput Screening Method for the Determination of Aqueous Drug Solubility Using Laser Nephelometry in Microtiter Plates
inferredcites →https://doi.org/10.1023/a:1007516718048openalex-snapshot
What is the True Solubility Advantage for Amorphous Pharmaceuticals?
inferredcites →https://doi.org/10.1081/pdt-120002237openalex-snapshot
Stabilization of Pharmaceuticals to Oxidative Degradation
inferredcites →https://doi.org/10.1201/9781420048452.ch2openalex-snapshot
Stability Testing of New Drug Substances and Products
inferredcites →https://doi.org/10.3109/9781420081244-13openalex-snapshot
Bracketing and Matrixing Designs for Stability Testing of New Drug Substances and Products
inferredcites →https://doi.org/10.5860/choice.35-4499openalex-snapshot
Physical chemistry of surfaces
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Role of Preformulation in Development of Solid Dosage Forms
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Current Social, Clinical, and Scientific Environment of Pharmaceutical R&D
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The effect of crosslinker structure upon the rate of hydroperoxide formation in dried, crosslinked poly(vinylpyrrolidone)
inferred← citeshttps://doi.org/10.1002/app.38531openalex-snapshot
Microgels composed of poly(ethylene imine) and carboxymethoxycoumarin: pH‐dependent and photodependent integrity
inferred← citeshttps://doi.org/10.1007/s11095-020-02868-yopenalex-snapshot
Accelerated Forced Degradation of Therapeutic Peptides in Levitated Microdroplets
inferred← citeshttps://doi.org/10.1016/b978-0-323-99796-6.00017-5openalex-snapshot
Equilibrium Processes in Pharmaceutics
inferred← citeshttps://doi.org/10.1016/b978-0-444-63963-9.00002-6openalex-snapshot
The development of a pharmaceutical oral solid dosage forms
inferred← citeshttps://doi.org/10.1016/j.addr.2012.01.009openalex-snapshot
Advances in simultaneous DSC–FTIR microspectroscopy for rapid solid-state chemical stability studies: Some dipeptide drugs as examples
inferred← citeshttps://doi.org/10.1016/j.chroma.2009.02.004openalex-snapshot
Improvement of the high-speed logD assay using an injection marker for the water plug aspiration/injection method
inferred← citeshttps://doi.org/10.1016/j.chroma.2011.02.018openalex-snapshot
Stability-indicating micellar liquid chromatography method for three novel derivatives of zidovudine in aqueous and simulated gastric and intestinal fluids matrices
inferred← citeshttps://doi.org/10.1016/j.drudis.2011.11.007openalex-snapshot
Bridging solubility between drug discovery and development
inferred← citeshttps://doi.org/10.1016/j.drudis.2014.10.001openalex-snapshot
Molecular perspectives on solid-state phase transformation and chemical reactivity of drugs: metoclopramide as an example
inferred← citeshttps://doi.org/10.1016/j.ejps.2013.08.040openalex-snapshot
Compound selection for development – Is salt formation the ultimate answer? Experiences with an extended concept of the “100mg approach”
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2012.04.075openalex-snapshot
Development of a precipitation-resistant solution formulation to increase in vivo exposure of a poorly water-soluble compound
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2014.10.058openalex-snapshot
Synthesis, biological activity, and biopharmaceutical characterization of tacrine dimers as acetylcholinesterase inhibitors
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Upper critical solution temperature behavior of cinnamic acid and polyethyleneimine mixture and its effect on temperature-dependent release of liposome
inferred← citeshttps://doi.org/10.1016/j.progpolymsci.2014.07.010openalex-snapshot
Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review
inferred← citeshttps://doi.org/10.1016/j.tips.2018.10.006openalex-snapshot
Pharmaceutical Cocrystal Drug Products: An Outlook on Product Development
inferred← citeshttps://doi.org/10.1021/acs.molpharmaceut.5b00863openalex-snapshot
Mechanism of Dissolution-Induced Nanoparticle Formation from a Copovidone-Based Amorphous Solid Dispersion
inferred← citeshttps://doi.org/10.1021/acsomega.3c04071openalex-snapshot
Intrinsic Solubility of Ionizable Compounds from p K a Shift
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Identification of Suitable Formulations for High Dose Oral Studies in Rats Using In Vitro Solubility Measurements, the Maximum Absorbable Dose Model, and Historical Data Sets
inferred← citeshttps://doi.org/10.1021/mp500504qopenalex-snapshot
Preclinical Dose Number and Its Application in Understanding Drug Absorption Risk and Formulation Design for Preclinical Species
inferred← citeshttps://doi.org/10.1038/srep32745openalex-snapshot
Clustering drug-drug interaction networks with energy model layouts: community analysis and drug repurposing
inferred← citeshttps://doi.org/10.1039/c1lc20298gopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c4ce02523gopenalex-snapshot
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The curse and blessing of abundance—the evolution of drug interaction databases and their impact on drug network analysis
inferred← citeshttps://doi.org/10.1124/pr.112.005660openalex-snapshot
Strategies to Address Low Drug Solubility in Discovery and Development
inferred← citeshttps://doi.org/10.1201/9781315120492-7openalex-snapshot
Formulation Strategies and Practice Used for Drug Candidates with Water-Insoluble Properties for Toxicology, Biology, and Pharmacology Studies in Discovery Support
inferred← citeshttps://doi.org/10.1201/9781420009552.ch7openalex-snapshot
Formulation Strategies and Practice Used for Drug Candidates with Water-Insoluble Properties for Toxicology, Biology, and Pharmacology Studies in Discovery Support
inferred← citeshttps://doi.org/10.1208/s12248-011-9270-0openalex-snapshot
Evaluation of Physical and Chemical Changes in Pharmaceuticals Flown on Space Missions
inferred← citeshttps://doi.org/10.1248/bpb.b12-00046openalex-snapshot
Physicochemical Characterization and Toxicity of Decursin and Their Derivatives from Angelica gigas
inferred← citeshttps://doi.org/10.1517/17425247.2013.783563openalex-snapshot
Impact of preformulation on drug development
inferred← citeshttps://doi.org/10.3390/pharmaceutics12090879openalex-snapshot
Uncovering New Drug Properties in Target-Based Drug–Drug Similarity Networks
inferred← citeshttps://doi.org/10.3390/pharmaceutics13122117openalex-snapshot
Drug Repurposing Using Modularity Clustering in Drug-Drug Similarity Networks Based on Drug–Gene Interactions
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Preformulation Studies of Zidovudine Derivatives: Acid Dissociation Constants, Differential Scanning Calorimetry, Thermogravimetry, X-Ray Powder Diffractometry and Aqueous Stability Studies
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UV-Metric, pH-Metric and RP-HPLC Methods to Evaluate the Multiple pKa Values of a Polyprotic Basic Novel Antimalarial Drug Lead, Cyclen Bisquinoline
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Evaluation of the Physicochemical Properties of a Novel Antimalarial Drug Lead, Cyclen Bisquinoline
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