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Apoptosis inducing effects of 6-Methoxydihydrosanguinarine in HT29 colon carcinoma cells

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/j.1460-2075.1995.tb00245.xopenalex-snapshot
Cytotoxicity‐dependent APO‐1 (Fas/CD95)‐associated proteins form a death‐inducing signaling complex (DISC) with the receptor.
inferredcites →https://doi.org/10.1006/bbrc.1999.1576openalex-snapshot
The Antioxidant 4b,5,9b,10-Tetrahydroindeno[1,2-b]indole Inhibits Apoptosis by Preventing Caspase Activation Following Mitochondrial Depolarization
inferredcites →https://doi.org/10.1016/0092-8674(93)90719-7openalex-snapshot
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
inferredcites →https://doi.org/10.1016/s0092-8674(00)81266-0openalex-snapshot
FLICE, A Novel FADD-Homologous ICE/CED-3–like Protease, Is Recruited to the CD95 (Fas/APO-1) Death-Inducing Signaling Complex
inferredcites →https://doi.org/10.1016/s0960-9822(07)00420-4openalex-snapshot
Essential requirement for caspase-8/FLICE in the initiation of the Fas-induced apoptotic cascade
inferredcites →https://doi.org/10.1038/sj.cdd.4400783openalex-snapshot
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c
inferredcites →https://doi.org/10.1055/s-2001-15820openalex-snapshot
A New Tetrahydroprotoberberine N-Oxide Alkaloid and Anti-Platelet Aggregation Constituents of Corydalis tashiroi
inferredcites →https://doi.org/10.1056/nejm199305063281805openalex-snapshot
Treatment of Colonic and Rectal Adenomas with Sulindac in Familial Adenomatous Polyposis
inferredcites →https://doi.org/10.1056/nejm200006293422603openalex-snapshot
The Effect of Celecoxib, a Cyclooxygenase-2 Inhibitor, in Familial Adenomatous Polyposis
inferredcites →https://doi.org/10.1074/jbc.273.16.9357openalex-snapshot
Caspase-3 Is Required for DNA Fragmentation and Morphological Changes Associated with Apoptosis
inferredcites →https://doi.org/10.1093/jnci/83.11.757openalex-snapshot
Feasibility of a High-Flux Anticancer Drug Screen Using a Diverse Panel of Cultured Human Tumor Cell Lines
inferredcites →https://doi.org/10.1182/blood.v98.9.2603openalex-snapshot
Cellular stress response and apoptosis in cancer therapy
inferredcites →https://doi.org/10.3322/canjclin.50.1.7openalex-snapshot
Cancer statistics, 2000

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112542zenodo-depositor-declared
Triterpenoid saponins from the herb Hylomecon japonica
inferred← citeshttps://doi.org/10.1002/cbdv.202400815openalex-snapshot
Chemical Constituents and Biological Activities of the Hylomecon japonica (Thunb.) Prantl & Kündig – A comprehensive Review
inferred← citeshttps://doi.org/10.1002/ptr.7601openalex-snapshot
6‐Methoxydihydrosanguinarine induces apoptosis and autophagy in breast cancer MCF ‐7 cells by accumulating ROS to suppress the PI3K / AKT / mTOR signaling pathway
inferred← citeshttps://doi.org/10.1007/978-981-16-4779-6_4openalex-snapshot
Role of Plant Secondary Metabolites as Anticancer and Chemopreventive Agents
inferred← citeshttps://doi.org/10.1007/s12032-023-02129-zopenalex-snapshot
6-Methoxydihydrosanguinarine exhibits cytotoxicity and sensitizes TRAIL-induced apoptosis of hepatocellular carcinoma cells through ROS-mediated upregulation of DR5
inferred← citeshttps://doi.org/10.1016/b978-0-08-100085-4.00005-0openalex-snapshot
Phytochemical and biological research of Chelidonieae pharmaceutical resources
inferred← citeshttps://doi.org/10.1016/b978-0-12-398371-8.00001-5openalex-snapshot
Alkaloids
inferred← citeshttps://doi.org/10.1016/b978-0-443-41783-2.00015-4openalex-snapshot
Phytochemical and biological research of Chelidonieae pharmaceutical resources
inferred← citeshttps://doi.org/10.1016/b978-0-444-63749-9.00003-7openalex-snapshot
Plant-Derived Prooxidants as Potential Anticancer Therapeutics
inferred← citeshttps://doi.org/10.1016/j.bcp.2005.04.020openalex-snapshot
Reactive oxygen species-mediated induction of apoptosis by a plant alkaloid 6-methoxydihydrosanguinarine in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.ejphar.2026.178544openalex-snapshot
6-Methoxydihydrosanguinarine synergizes with cisplatin to enhance lung cancer cell death via ROS-mediated autophagy, ER stress, and JNK activation
inferred← citeshttps://doi.org/10.1016/j.hermed.2023.100628openalex-snapshot
Phytopharmaceutical properties and quality assessment of two Himalayan medicinal plants, Meconopsis horridula and Meconopsis simplicifolia
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.142170openalex-snapshot
Molecular interactions between fibrinogen and 6-methoxydihydrosanguinarine and their modulation of anticancer activity in melanoma A375 cells
inferred← citeshttps://doi.org/10.1016/j.jep.2013.09.052openalex-snapshot
A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain
inferred← citeshttps://doi.org/10.1016/j.jpba.2009.08.014openalex-snapshot
Racemization of 6-methoxydihydrosanguinarine in methanol investigated by enantioselective dynamic HPLC
inferred← citeshttps://doi.org/10.1016/j.jpba.2011.06.002openalex-snapshot
Chiral HPLC studies on chemical behavior of 6-methoxydihydrosanguinarine in alcoholic solvent system
inferred← citeshttps://doi.org/10.1016/j.nut.2008.10.019openalex-snapshot
Inhibition of proliferation and induction of apoptosis by γ-tocotrienol in human colon carcinoma HT-29 cells
inferred← citeshttps://doi.org/10.1016/s1099-4831(07)64001-2openalex-snapshot
Chapter 1 Molecular Modes of Action of Cytotoxic Alkaloids: From DNA Intercalation, Spindle Poisoning, Topoisomerase Inhibition to Apoptosis and Multiple Drug Resistance
inferred← citeshttps://doi.org/10.1016/s1674-6384(14)60001-0openalex-snapshot
Chemical Constituents of Plants from Tribe Chelidonieae and their Bioactivities
inferred← citeshttps://doi.org/10.1080/14786419.2024.2429122openalex-snapshot
Isoquinoline alkaloids with bioactive constituents from the roots and rhizomes of Hylomecon japonica
inferred← citeshttps://doi.org/10.1186/s12906-024-04497-zopenalex-snapshot
Exploring the mechanism of 6-Methoxydihydrosanguinarine in the treatment of lung adenocarcinoma based on network pharmacology, molecular docking and experimental investigation
inferred← citeshttps://doi.org/10.2174/138945012802009044openalex-snapshot
Pro-Oxidant Natural Products as Anticancer Agents
inferred← citeshttps://doi.org/10.3390/horticulturae11010060openalex-snapshot
Hylomecon japonica: A Review About Botanical Aspects, Traditional Applications, Chemical Composition, and Pharmacological Properties
inferred← citeshttps://doi.org/10.3390/molecules22081299openalex-snapshot
γ-Tocotrienol Inhibits Proliferation and Induces Apoptosis via the Mitochondrial Pathway in Human Cervical Cancer HeLa Cells
inferred← citeshttps://doi.org/10.3390/molecules22101731openalex-snapshot
New Triterpenoid Saponins from the Herb Hylomecon japonica
inferred← citeshttps://doi.org/10.6084/m9.figshare.25893776openalex-snapshot
Additional file 1 of Exploring the mechanism of 6-Methoxydihydrosanguinarine in the treatment of lung adenocarcinoma based on network pharmacology, molecular docking and experimental investigation
inferred← citeshttps://doi.org/10.70675/79eab759z23cfz4f10z9922z589b6541cc70openalex-snapshot
Considérations sur l’histoire naturelle des Ranunculales
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