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The mechanisms of alloxan- and streptozotocin-induced diabetes

https://doi.org/10.1007/s00125-007-0886-7

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Outgoing claims: the papers this work cites, builds on, or argues with.

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Clinical antitumor activity and toxicity of streptozotocin (NSC-85998)

inferredcites →https://doi.org/10.1002/jlac.18380260302openalex-snapshot

Untersuchungen über die Natur der Harnsäure

inferredcites →https://doi.org/10.1006/abbi.1999.1666openalex-snapshot

Importance of Cysteine Residues for the Stability and Catalytic Activity of Human Pancreatic Beta Cell Glucokinase

inferredcites →https://doi.org/10.1006/bbrc.1993.2641openalex-snapshot

Biochemical Evidence for Nitric Oxide Formation from Streptozotocin in Isolated Pancreatic Islets

inferredcites →https://doi.org/10.1007/978-1-4612-4112-6_8openalex-snapshot

Alloxan derivatives as a tool for the elucidation of the mechanism of the diabetogenic action of alloxan

inferredcites →https://doi.org/10.1007/bf00169009openalex-snapshot

Inhibition of aconitase by alloxan and the differential modes of protection of glucose, 3-O-methylglucose, and mannoheptulose

inferredcites →https://doi.org/10.1007/bf00257736openalex-snapshot

Alloxan diabetes: The sorcerer and his apprentice

inferredcites →https://doi.org/10.1007/bf00282526openalex-snapshot

Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro

inferredcites →https://doi.org/10.1007/bf00428976openalex-snapshot

Autoradiographic study of the distribution and cellular uptake of (14C)-streptozotocin in the rat

inferredcites →https://doi.org/10.1007/bf00429866openalex-snapshot

On the accumulation of alloxan in the pancreatic ?-cells

inferredcites →https://doi.org/10.1007/bf01919538openalex-snapshot

N-Monomethyl-arginine and nicotinamide prevent streptozotocin-induced double strand DNA break formation in pancreatic rat islets

inferredcites →https://doi.org/10.1007/bf01949404openalex-snapshot

The prevention of alloxan-induced diabetes in mice by the iron-chelator detapac: Suggestion of a role for iron in the cytotoxic process

inferredcites →https://doi.org/10.1007/bf02341500openalex-snapshot

Alloxan: history and mechanism of action

inferredcites →https://doi.org/10.1007/s000180050505openalex-snapshot

Classical and new diabetogenscomparison of their effects on isolated rat pancreatic islets in vitro

inferredcites →https://doi.org/10.1007/s00125-002-0955-xopenalex-snapshot

Importance of the GLUT2 glucose transporter for pancreatic beta cell toxicity of alloxan

inferredcites →https://doi.org/10.1007/s00125-003-1241-2openalex-snapshot

Mechanism underlying resistance of human pancreatic beta cells against toxicity of streptozotocin and alloxan

inferredcites →https://doi.org/10.1007/s001250051564openalex-snapshot

Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

inferredcites →https://doi.org/10.1016/0005-2787(76)90245-8openalex-snapshot

Proinsulin biosynthesis by pancreatic islets of the rat and the study of alloxan cytotoxicity in vitro

inferredcites →https://doi.org/10.1016/0006-2952(76)90502-5openalex-snapshot

Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate

inferredcites →https://doi.org/10.1016/0006-2952(88)90201-8openalex-snapshot

Signal recognition by pancreatic B-cells

inferredcites →https://doi.org/10.1016/0006-2952(88)90207-9openalex-snapshot

Dialuric acid autoxidation

inferredcites →https://doi.org/10.1016/0006-2952(89)90037-3openalex-snapshot

Glutathione-mediated redox cycling of alloxan

inferredcites →https://doi.org/10.1016/0006-2952(89)90206-2openalex-snapshot

Auto-oxidation of dialuric acid, divicine and isouramil

inferredcites →https://doi.org/10.1016/0006-2952(91)90230-3openalex-snapshot

Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells

inferredcites →https://doi.org/10.1016/0006-2952(91)90449-fopenalex-snapshot

Thiol-group reactivity, hydrophilicity and stability of alloxan, its reduction products and its N-methyl derivatives and a comparison with ninhydrin

inferredcites →https://doi.org/10.1016/0006-2952(95)02102-7openalex-snapshot

Comparison of inhibition of glucose-stimulated insulin secretion in rat islets of Langerhans by Streptozotocin and methyl and ethyl nitrosoureas and methanesulphonates

inferredcites →https://doi.org/10.1016/0014-5793(79)80877-7openalex-snapshot

Influence of trace metals on alloxan cytotoxicity in pancreatic islets

inferredcites →https://doi.org/10.1016/0167-4889(84)90064-8openalex-snapshot

Effects of streptozotocin on a clonal isolate of rat insulinoma cells

inferredcites →https://doi.org/10.1016/0303-7207(88)90198-0openalex-snapshot

Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations

inferredcites →https://doi.org/10.1016/0304-4165(81)90093-3openalex-snapshot

Effects of alloxan on the islets of Langerhans inhibition of leucine metabolism and insulin secretion

inferredcites →https://doi.org/10.1016/0891-5849(88)90036-6openalex-snapshot

Free radicals and diabetes

inferredcites →https://doi.org/10.1016/b978-0-12-187820-7.50021-8openalex-snapshot

Action of Toxic Drugs on Islet Cells

inferredcites →https://doi.org/10.1016/j.freeradbiomed.2006.06.002openalex-snapshot

Relative importance of cellular uptake and reactive oxygen species for the toxicity of alloxan and dialuric acid to insulin-producing cells

inferredcites →https://doi.org/10.1016/s0006-2952(98)00370-0openalex-snapshot

Site-specific DNA methylation and apoptosis: induction by diabetogenic streptozotocin

inferredcites →https://doi.org/10.1016/s0021-9258(17)35111-6openalex-snapshot

ALLOXAN STUDIES: THE ACTION OF ALLOXAN HOMOLOGUES AND RELATED COMPOUNDS

inferredcites →https://doi.org/10.1016/s0021-9258(18)57074-5openalex-snapshot

ALLOXAN AND DIALURIC ACID: THEIR STABILITIES AND ULTRAVIOLET ABSORPTION SPECTRA

inferredcites →https://doi.org/10.1016/s0021-9258(19)42751-8openalex-snapshot

The Generation of Hydrogen Peroxide, Superoxide Radical, and Hydroxyl Radical by 6-Hydroxydopamine, Dialuric Acid, and Related Cytotoxic Agents

inferredcites →https://doi.org/10.1016/s0021-9258(20)65108-0openalex-snapshot

Protection by superoxide dismutase, catalase, and poly(ADP-ribose) synthetase inhibitors against alloxan- and streptozotocin-induced islet DNA strand breaks and against the inhibition of proinsulin synthesis.

inferredcites →https://doi.org/10.1016/s0022-3565(25)31849-5openalex-snapshot

Protection against alloxan-induced diabetes by various urea derivatives: relationship between protective effects and reactivity with the hydroxyl radical.

inferredcites →https://doi.org/10.1016/s0026-895x(25)09757-3openalex-snapshot

Inhibition of glucokinase by alloxan through interaction with SH groups in the sugar-binding site of the enzyme.

inferredcites →https://doi.org/10.1016/s0026-895x(25)13767-xopenalex-snapshot

Molecular Requirements for Recognition at a Glucoreceptor for Insulin Release

inferredcites →https://doi.org/10.1016/s0031-6997(25)06885-1openalex-snapshot

DRUGS PRODUCING DIABETES THROUGH DAMAGE OF THE INSULIN SECRETING CELLS

inferredcites →https://doi.org/10.1016/s0140-6736(00)42072-6openalex-snapshot

NECROSIS OF ISLETS OF LANGERHANS PRODUCED EXPERIMENTALLY

inferredcites →https://doi.org/10.1016/s0140-6736(00)87397-3openalex-snapshot

EXPERIMENTAL ALLOXAN DIABETES IN THE RAT

inferredcites →https://doi.org/10.1016/s0165-6147(99)01292-4openalex-snapshot

Poly (ADP-ribose) polymerase, nitric oxide and cell death

inferredcites →https://doi.org/10.1016/s0271-5317(85)80228-1openalex-snapshot

Modification of streptozotocin-induced diabetes by protective agents

inferredcites →https://doi.org/10.1016/s0891-5849(98)00325-6openalex-snapshot

Effect of superoxide dismutase, catalase, chelating agents, and free radical scavengers on the toxicity of alloxan to isolated pancreatic islets in vitro

inferredcites →https://doi.org/10.1034/j.1600-0633.2002.290402.xopenalex-snapshot

Scavenging effect of melatonin on hydroxyl radicals generated by alloxan

inferredcites →https://doi.org/10.1038/294284a0openalex-snapshot

Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

inferredcites →https://doi.org/10.1038/6535openalex-snapshot

Mice lacking the poly(ADP-ribose) polymerase gene are resistant to pancreatic beta-cell destruction and diabetes development induced by streptozocin

inferredcites →https://doi.org/10.1042/bj1820017openalex-snapshot

Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

inferredcites →https://doi.org/10.1042/bj2080513openalex-snapshot

Selective uptake of alloxan by pancreatic B-cells

inferredcites →https://doi.org/10.1055/s-0028-1093913openalex-snapshot

Acute Effects of Alloxan on the Metabolism and Insulin Secretion of the Pancreatic B-Cell

inferredcites →https://doi.org/10.1055/s-0029-1210860openalex-snapshot

Survival and B-Cell Function of Mouse Pancreatic Islets Maintained in Culture after Concomitant Exposure to Streptozotocin and Nicotinamide

inferredcites →https://doi.org/10.1055/s-2002-20527openalex-snapshot

Formation of Compound 305 Requires the Simultaneous Generation of Both Alloxan and GSH Radicals

inferredcites →https://doi.org/10.1073/pnas.96.5.2301openalex-snapshot

Poly(ADP-ribose) polymerase gene disruption conferred mice resistant to streptozotocin-induced diabetes

inferredcites →https://doi.org/10.1073/pnas.96.6.3059openalex-snapshot

Poly(ADP-ribose) polymerase-deficient mice are protected from streptozotocin-induced diabetes

inferredcites →https://doi.org/10.1089/ars.2007.1816openalex-snapshot

Relation Between Triketone Structure, Generation of Reactive Oxygen Species, and Selective Toxicity of the Diabetogenic Agent Alloxan

inferredcites →https://doi.org/10.1111/j.1476-5381.1988.tb11714.xopenalex-snapshot

Structural requirements of alloxan and ninhydrin for glucokinase inhibition and of glucose for protection against inhibition

inferredcites →https://doi.org/10.1126/science.108.2803.308openalex-snapshot

The Mechanism of Cysteine and Glutathione Protection Against Alloxan Diabetes

inferredcites →https://doi.org/10.1126/science.115.2976.41openalex-snapshot

Reversal of the Diabetogenic Action of Alloxan by Sulfhydryl Compounds

inferredcites →https://doi.org/10.1155/edr.2000.211openalex-snapshot

Streptozotocin and Alloxan‐based Selection Improves Toxin Resistance of Insulin‐Producing RINm Cells

inferredcites →https://doi.org/10.1210/en.130.6.3522openalex-snapshot

Long term in vitro effects of streptozotocin, interleukin-1, and high glucose concentration on the activity of mitochondrial dehydrogenases and the secretion of insulin in pancreatic islets

inferredcites →https://doi.org/10.1210/endo-102-6-1847openalex-snapshot

Alloxan Uptake by Isolated Rat Islets of Langerhans*

inferredcites →https://doi.org/10.1210/endo-113-3-943openalex-snapshot

Uptake of Labeled Alloxan in Mouse Organs and Mitochondriain Vivoandin Vitro*

inferredcites →https://doi.org/10.1210/endo-123-2-1001openalex-snapshot

Defective Catabolism of D-Glucose and L-Glutamine in Mouse Pancreatic Islets Maintained in Culture after Streptozotocin Exposure*

inferredcites →https://doi.org/10.1210/endo-33-5-297openalex-snapshot

ALLOXAN DIABETES IN THE DOG1

inferredcites →https://doi.org/10.1248/bpb1978.13.259openalex-snapshot

Allopurinol protects pancreatic .BETA. cells from the cytotoxic effect of streptozotocin: In vitro study.

inferredcites →https://doi.org/10.1248/cpb.34.4731openalex-snapshot

Inhibition of rat liver glucokinase by alloxan and ninhydrin.

inferredcites →https://doi.org/10.1530/acta.0.0200081openalex-snapshot

THE DIABETOGENIC EFFECT OF ALLOXAN AFTER ELIMINATION OF EXTRA-PANCREATIC FACTORS

inferredcites →https://doi.org/10.1530/acta.0.1150021openalex-snapshot

Glucokinase in pancreatic B-cells and its inhibition by alloxan

inferredcites →https://doi.org/10.1677/joe.0.0690455openalex-snapshot

DISTRIBUTION OF LABELLED STREPTOZOTOCIN IN MICE: UPTAKE AND RETENTION IN PANCREATIC ISLETS

inferredcites →https://doi.org/10.1677/joe.0.1390153openalex-snapshot

The relationship between the physicochemical properties and the biological effects of alloxan and several N-alkyl substituted alloxan derivatives

inferredcites →https://doi.org/10.1677/joe.0.1550283openalex-snapshot

Comparative toxicity of alloxan, N-alkylalloxans and ninhydrin to isolated pancreatic islets in vitro

inferredcites →https://doi.org/10.2220/biomedres.12.297openalex-snapshot

INHIBITION OF GLUCOKINASE AND HEXOKINASE FROM PANCREATIC B-CELLS AND LIVER BY ALLOXAN, ALLOXANTIN, DIALURIC ACID, AND t-BUTYLHYDROPEROXIDE

inferredcites →https://doi.org/10.2337/diab.16.1.51openalex-snapshot

Light and Electron Microscopy of Lesions in Rats Rendered Diabetic with Streptozotocin

inferredcites →https://doi.org/10.2337/diab.25.7.574openalex-snapshot

Interaction of Alloxan and Anomers of D-Glucose on Glucose-induced Insulin Secretion and Biosynthesis in Vitro

inferredcites →https://doi.org/10.2337/diab.27.12.1205openalex-snapshot

Alloxan Stimulation and Inhibition of Insulin Release from Isolated Rat Islets of Langerhans

inferredcites →https://doi.org/10.2337/diab.35.10.1163openalex-snapshot

Identification of Glucokinase as an Alloxan-Sensitive Glucose Sensor of the Pancreatic β-Cell

inferredcites →https://doi.org/10.2337/diab.35.8.866openalex-snapshot

Mechanisms of Nitrosourea-Induced β-Cell Damage: Alterations in DNA

inferredcites →https://doi.org/10.2337/diab.37.2.213openalex-snapshot

Mechanisms of Nitrosourea-Induced β-Cell Damage: Activation of Poly (ADP-Ribose) Synthetase and Cellular Distribution

inferredcites →https://doi.org/10.2337/diab.43.11.1326openalex-snapshot

STZ Transport and Cytotoxicity: Specific Enhancement in GLUT2-Expressing Cells

inferredcites →https://doi.org/10.2337/diab.46.11.1733openalex-snapshot

Relation Between Antioxidant Enzyme Gene Expression and Antioxidative Defense Status of Insulin-Producing Cells

inferredcites →https://doi.org/10.2337/diab.47.1.50openalex-snapshot

GLUT2 in Pancreatic Islets: Crucial Target Molecule in Diabetes Induced With Multiple Low Doses of Streptozotocin in Mice

inferredcites →https://doi.org/10.3164/jcbn.1.237openalex-snapshot

Parallel Inhibition of Islet Glucokinase and Glucose-Stimulated Insulin Secretion by Either Alloxan or Ninhydrin

inferredcites →https://doi.org/10.3181/00379727-58-14907openalex-snapshot

Acute Nature of Alloxan Damage.

inferredcites →https://doi.org/10.3181/00379727-63-15651openalex-snapshot

Diabetes Mellitus in Rabbits Injected with Dialuric Acid.

inferredcites →https://doi.org/10.3181/00379727-71-17263openalex-snapshot

Effect of Alloxan in Rabbits with Temporary Occlusion of the Arteries to the Pancreas.

inferredcites →https://doi.org/10.33549/physiolres.930111openalex-snapshot

The mechanism of alloxan and streptozotocin action in B cells of the rat pancreas

inferredcites →https://doi.org/10.3892/ijmm.7.3.311openalex-snapshot

Pancreatic uptake of [2-14C]alloxan

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1002/jbt.70653openalex-snapshot

Investigation of the Effects of Saxagliptin in In Vitro and In Vivo Models of Diabetic Neuropathy

inferred← citeshttps://doi.org/10.1002/jcb.27649openalex-snapshot

Alterations in lipid peroxidation, lipid profile, insulin sensitivity, and hepatic histopathological changes in diabetic rats following the treatment with Salvadora persica

inferred← citeshttps://doi.org/10.1002/jcb.28437openalex-snapshot

Antidiabetic properties of aqueous and methanol extracts from the trunk bark of Ceiba pentandra in type 2 diabetic rat

inferred← citeshttps://doi.org/10.1002/jcp.26062openalex-snapshot

High fat diet attenuates hyperglycemia, body composition changes, and bone loss in male streptozotocin‐induced type 1 diabetic mice

inferred← citeshttps://doi.org/10.1002/jemt.22065openalex-snapshot

Ultrastructural alterations in colon absorptive cells of alloxan‐induced diabetic rats submitted to long‐term physical training

inferred← citeshttps://doi.org/10.1002/jmri.25955openalex-snapshot

Usefulness of Sweep Imaging With Fourier Transform for Evaluation of Cortical Bone in Diabetic Rats

inferred← citeshttps://doi.org/10.1002/jsfa.71005openalex-snapshot

Dietary eriodictyol ameliorates hyperglycemia and multi‐organ damage in streptozotocin‐induced diabetic mice: involvement of insulin signaling and antioxidant responses

inferred← citeshttps://doi.org/10.1002/prca.201400135openalex-snapshot

The beta‐cell in type 1 diabetes: What have we learned from proteomic studies?

inferred← citeshttps://doi.org/10.1002/prp2.306openalex-snapshot

Chronic treatment of (R)‐α‐lipoic acid reduces blood glucose and lipid levels in high‐fat diet and low‐dose streptozotocin‐induced metabolic syndrome and type 2 diabetes in Sprague‐Dawley rats

inferred← citeshttps://doi.org/10.1002/psc.3017openalex-snapshot

Characterization of an insulinotropic peptide from skin secretions of Odorrana andersonii

inferred← citeshttps://doi.org/10.1002/ptr.3182openalex-snapshot

Pharmacodynamic action of a commercial preparation of the mushroomCoprinus comatusin rats

inferred← citeshttps://doi.org/10.1002/ptr.3524openalex-snapshot

Prevention of Chemically Induced Diabetes Mellitus in Experimental Animals by Virgin Argan Oil

inferred← citeshttps://doi.org/10.1002/ptr.4769openalex-snapshot

Antihyperglycemic Activity of Extracts from Boldoa purpurascens Leaves in Alloxan‐Induced Diabetic Rats

inferred← citeshttps://doi.org/10.1002/ptr.5255openalex-snapshot

Hypoglycaemic Activity of CulinaryPleurotus ostreatusandP.cystidiosusMushrooms in Healthy Volunteers and Type 2 Diabetic Patients on Diet Control and the Possible Mechanisms of Action

inferred← citeshttps://doi.org/10.1002/ptr.6589openalex-snapshot

Withania somnifera (Indian ginseng) in diabetes mellitus: A systematic review and meta‐analysis of scientific evidence from experimental research to clinical application

inferred← citeshttps://doi.org/10.1002/qua.24441openalex-snapshot

Theoretical investigation of the alloxan-dialuric acid redox cycle

inferred← citeshttps://doi.org/10.1002/stem.1492openalex-snapshot

Efficient β-cell regeneration by a combination of neogenesis and replication following β-cell ablation and reversal of pancreatic duct ligation

inferred← citeshttps://doi.org/10.1002/stem.482openalex-snapshot

Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells

inferred← citeshttps://doi.org/10.1002/tox.22460openalex-snapshot

Cellular apoptosis and cardiac dysfunction in STZ‐induced diabetic rats attenuated by anthocyanins via activation of IGFI‐R/PI3K/Akt survival signaling

inferred← citeshttps://doi.org/10.1007/978-1-0716-0385-7_1openalex-snapshot

Practical Considerations when Using Mouse Models of Diabetes

inferred← citeshttps://doi.org/10.1007/978-1-0716-0385-7_5openalex-snapshot

Rat Models of Human Type 1 Diabetes

inferred← citeshttps://doi.org/10.1007/978-1-0716-1558-4_10openalex-snapshot

Evaluation of Antidiabetic Properties of Adenosma Bracteosum Bonati Extracts in Mice with Streptozotocin-Induced Diabetes

inferred← citeshttps://doi.org/10.1007/978-1-4939-8994-2_17openalex-snapshot

An Analysis of the Intracellular Signal Transduction of Peripheral Blood Leukocytes in Animal Models of Diabetes Using Flow Cytometry

inferred← citeshttps://doi.org/10.1007/978-1-60761-132-5_3openalex-snapshot

Pancreatic Regeneration

inferred← citeshttps://doi.org/10.1007/978-1-60761-366-4_4openalex-snapshot

Islet Regeneration

inferred← citeshttps://doi.org/10.1007/978-1-60761-956-7_2openalex-snapshot

Experimental Models of Oxidative Stress Related to Cardiovascular Diseases and Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-030-04624-8_35openalex-snapshot

Nutraceuticals for Diabetes in Dogs and Cats

inferred← citeshttps://doi.org/10.1007/978-3-030-11748-1_14openalex-snapshot

Animal Models of Type 2 Diabetes, Obesity and Nonalcoholic Steatohepatitis – Clinical Translatability and Applicability in Preclinical Drug Development

inferred← citeshttps://doi.org/10.1007/978-3-030-48798-0_9openalex-snapshot

Novel Prospective of N. sativa Essential Oil Analysis, Culinary and Medicinal Uses

inferred← citeshttps://doi.org/10.1007/978-3-030-73317-9_76-1openalex-snapshot

Current Assays in Endocrine Safety Pharmacology

inferred← citeshttps://doi.org/10.1007/978-3-030-81303-1_69-1openalex-snapshot

Biomarkers in Experimental Diabetes: Studies with Syzygium Cumini (L.) and Links with the Sulfonylurea 1 Receptor

inferred← citeshttps://doi.org/10.1007/978-3-031-02583-9openalex-snapshot

Biologic Foundations for Skeletal Tissue Engineering

inferred← citeshttps://doi.org/10.1007/978-3-031-08014-2_69openalex-snapshot

Biomarkers in Experimental Diabetes: Studies with Syzygium Cumini (L.) and Links with the Sulfonylurea 1 Receptor

inferred← citeshttps://doi.org/10.1007/978-3-031-35529-5_76openalex-snapshot

Current Assays in Endocrine Safety Pharmacology

inferred← citeshttps://doi.org/10.1007/978-3-031-41943-0_24openalex-snapshot

Modelling of Beta Cell Pathophysiology Using Stem Cell-Derived Islets

inferred← citeshttps://doi.org/10.1007/978-3-031-55715-6_19openalex-snapshot

Experimental Animal Models in Research: Diabetes and Impaired Wound Healing

inferred← citeshttps://doi.org/10.1007/978-3-031-62806-1_15openalex-snapshot

Is Homocysteine a Biomarker of Environmental Health Risk and Epigenetic-DNA Methylation: Links to Cardiovascular Pathogenesis and B Vitamins

inferred← citeshttps://doi.org/10.1007/978-3-031-96364-3_12openalex-snapshot

Monoamine-Uptake Inhibitors and Pain: Antidepressant Drugs Among First-Line Treatments Against Neuropathic Pain and Fibromyalgia

inferred← citeshttps://doi.org/10.1007/978-3-319-14559-4_12openalex-snapshot

The Transplantation of Insulin Producing Tissue

inferred← citeshttps://doi.org/10.1007/978-3-319-18741-9_11openalex-snapshot

Rodent Models of Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-319-20797-1_11-1openalex-snapshot

Rodent Models of Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-642-30018-9_115openalex-snapshot

Free Radical Biology and Reproductive Health in Diabetes

inferred← citeshttps://doi.org/10.1007/978-90-481-3271-3_24openalex-snapshot

Immunology of β-Cell Destruction

inferred← citeshttps://doi.org/10.1007/978-981-13-0971-7_8openalex-snapshot

Experimental Study of Electroacupuncture Therapy in Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/978-981-13-6920-9_11openalex-snapshot

Screening of Natural Antidiabetic Agents

inferred← citeshttps://doi.org/10.1007/978-981-15-1636-8_28openalex-snapshot

Protective Effect of Mimusops elengi L. on Renal and Hepatic Markers in STZ-Induced Diabetic Rats

inferred← citeshttps://doi.org/10.1007/978-981-15-7305-7_9openalex-snapshot

Scope of Honey in Diabetes and Metabolic Disorders

inferred← citeshttps://doi.org/10.1007/978-981-99-0015-2_5openalex-snapshot

Potential of Bamboo in the Prevention of Diabetes-Related Disorders: Possible Mechanisms for Prevention

inferred← citeshttps://doi.org/10.1007/s00044-017-1895-9openalex-snapshot

A novel PTP1b inhibitor vanadium-flavone complex: synthesis and pharmacodynamic evaluation in streptozotocin-induced diabetic mice

inferred← citeshttps://doi.org/10.1007/s00109-018-1707-9openalex-snapshot

Hypoxia-inducible factor 1α protects peripheral sensory neurons from diabetic peripheral neuropathy by suppressing accumulation of reactive oxygen species.

inferred← citeshttps://doi.org/10.1007/s00109-020-01878-yopenalex-snapshot

ASK1 inhibition: a therapeutic strategy with multi-system benefits

inferred← citeshttps://doi.org/10.1007/s00125-009-1383-yopenalex-snapshot

In vivo imaging of murine endocrine islets of Langerhans with extended-focus optical coherence microscopy

inferred← citeshttps://doi.org/10.1007/s00125-009-1536-zopenalex-snapshot

Insights into the critical role of NADPH oxidase(s) in the normal and dysregulated pancreatic beta cell

inferred← citeshttps://doi.org/10.1007/s00125-011-2365-4openalex-snapshot

Reduction of both beta cell death and alpha cell proliferation by dipeptidyl peptidase-4 inhibition in a streptozotocin-induced model of diabetes in mice

inferred← citeshttps://doi.org/10.1007/s00125-014-3175-2openalex-snapshot

In vivo activation of the PI3K–Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes

inferred← citeshttps://doi.org/10.1007/s00125-014-3311-zopenalex-snapshot

Mig6 haploinsufficiency protects mice against streptozotocin-induced diabetes

inferred← citeshttps://doi.org/10.1007/s00125-015-3745-yopenalex-snapshot

Heterozygous inactivation of plasma membrane Ca2+-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability

inferred← citeshttps://doi.org/10.1007/s00125-022-05812-4openalex-snapshot

Autoantibody and T cell responses to oxidative post-translationally modified insulin neoantigenic peptides in type 1 diabetes

inferred← citeshttps://doi.org/10.1007/s00198-018-4392-1openalex-snapshot

Pulsed electromagnetic fields preserve bone architecture and mechanical properties and stimulate porous implant osseointegration by promoting bone anabolism in type 1 diabetic rabbits

inferred← citeshttps://doi.org/10.1007/s00210-019-01769-1openalex-snapshot

Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat—another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats

inferred← citeshttps://doi.org/10.1007/s00210-023-02496-4openalex-snapshot

A delve into the pharmacological targets and biological mechanisms of Paederia foetida Linn.: a rather invaluable traditional medicinal plant

inferred← citeshttps://doi.org/10.1007/s00210-023-02535-0openalex-snapshot

Roflumilast ameliorates diabetic nephropathy in rats through down-regulation of JAK/STAT signaling pathway

inferred← citeshttps://doi.org/10.1007/s00210-023-02802-0openalex-snapshot

Current advancement in the preclinical models used for the assessment of diabetic neuropathy

inferred← citeshttps://doi.org/10.1007/s00210-024-03470-4openalex-snapshot

Determination of beneficial effects of cuminaldehyde on hyperglycemia associated kidney malfunctions

inferred← citeshttps://doi.org/10.1007/s00210-025-03992-5openalex-snapshot

Ameliorative and protective effects of coenzyme Q10 against natural and chemical toxicity: a narrative review

inferred← citeshttps://doi.org/10.1007/s00213-019-05443-5openalex-snapshot

Catecholaminergic and opioidergic system mediated effects of reboxetine on diabetic neuropathic pain

inferred← citeshttps://doi.org/10.1007/s00299-012-1329-6openalex-snapshot

Superoxide production induced by short-term exposure of barley roots to cadmium, auxin, alloxan and sodium dodecyl sulfate

inferred← citeshttps://doi.org/10.1007/s00335-014-9533-zopenalex-snapshot

Approach to assessing determinants of glucose homeostasis in the conscious mouse

inferred← citeshttps://doi.org/10.1007/s00335-018-9742-yopenalex-snapshot

Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11

inferred← citeshttps://doi.org/10.1007/s00418-023-02207-3openalex-snapshot

The effects of hydroxytyrosol on Prdx6 and insulin expression in diabetic rat pancreases

inferred← citeshttps://doi.org/10.1007/s00425-014-2030-5openalex-snapshot

Low Cd concentration-activated morphogenic defence responses are inhibited by high Cd concentration-induced toxic superoxide generation in barley root tip

inferred← citeshttps://doi.org/10.1007/s00436-016-4991-8openalex-snapshot

Evaluation of conventional therapeutic methods versus maggot therapy in the evolution of healing of tegumental injuries in Wistar rats with and without diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s00441-014-1941-6openalex-snapshot

Effects of maternal diabetes on male offspring: high cell proliferation and increased activity of MMP-2 in the ventral prostate

inferred← citeshttps://doi.org/10.1007/s00441-019-03158-9openalex-snapshot

Porcine models for studying complications and organ crosstalk in diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s00580-011-1293-5openalex-snapshot

Comparative effects of oral administration of Citrullus colocynthis and insulin injection on serum biochemical parameters of alloxan-induced diabetic dogs

inferred← citeshttps://doi.org/10.1007/s00580-011-1381-6openalex-snapshot

A comparison between metformin and garlic on alloxan-induced diabetic dogs

inferred← citeshttps://doi.org/10.1007/s00580-012-1415-8openalex-snapshot

Antidiabetic effect of Orchis anatolica root extracts on alloxan-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s00580-014-1963-1openalex-snapshot

Antidiabetic effect of Artemisia absinthium extracts on alloxan-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s00580-015-2127-7openalex-snapshot

Haematologic profile and histomorphologic assessment of the pancreas and liver of alloxan-induced diabetic rats treated with graded concentration of quail egg

inferred← citeshttps://doi.org/10.1007/s00580-018-2712-7openalex-snapshot

Nephroprotective activity of Alyssum meniocoides Boiss aqueous extract on streptozotocin-induced diabetic nephrotoxicity in male mice

inferred← citeshttps://doi.org/10.1007/s00580-018-2754-xopenalex-snapshot

Evaluation of hematoprotective and hepatoprotective properties of aqueous extract of Ceterach officinarum DC against streptozotocin-induced hepatic injury in male mice

inferred← citeshttps://doi.org/10.1007/s00580-018-2789-zopenalex-snapshot

A comparative study of hepatoprotective effect of Inula britannica L aqueous extract and glibenclamide in streptozotocin-induced diabetic mice

inferred← citeshttps://doi.org/10.1007/s00580-021-03240-1openalex-snapshot

Topical application of Azadirachta indica improves epidermal wound healing in hyperglycemic rats

inferred← citeshttps://doi.org/10.1007/s00580-022-03347-zopenalex-snapshot

Phlogacanthus thyrsiflorus Nees. modulates hepatic and renal apoptosis via attenuation of oxidative stress in alloxan-administered mice

inferred← citeshttps://doi.org/10.1007/s00580-024-03598-yopenalex-snapshot

Aggravated dyslipidemia in diabetic albino rats after subchronic oral aluminium chloride exposure

inferred← citeshttps://doi.org/10.1007/s00580-025-03687-6openalex-snapshot

Effects of exercise on some hemostatic parameters in experimental diabetes model induced by streptozotosin (STZ) in rats

inferred← citeshttps://doi.org/10.1007/s00580-025-03713-7openalex-snapshot

Hypoglycemic effects of methanolic extract of lemon verbena in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s00580-025-03733-3openalex-snapshot

Spiral ginger (Costus afer) leaves and stem abate hyperglycemia via inhibition of key enzymes relevant to type 2 diabetes and downregulation of insulin gene

inferred← citeshttps://doi.org/10.1007/s00580-026-03836-5openalex-snapshot

Nutritional composition of two okra (Abelmoschus esculentus) cultivars and the antidiabetic effects of their formulated diets on type 2 diabetic rat model

inferred← citeshttps://doi.org/10.1007/s00580-026-03854-3openalex-snapshot

Haematological and electrocardiographic safety of adrenergic antagonists and glibenclamide co-administration in streptozotocin-induced diabetic Wistar rats

inferred← citeshttps://doi.org/10.1007/s00702-025-02896-1openalex-snapshot

Insulin signaling disruption exacerbates memory impairment and seizure susceptibility in an epilepsy model with Alzheimer’s disease-like pathology

inferred← citeshttps://doi.org/10.1007/s00709-025-02096-4openalex-snapshot

Anti-inflammatory and anti-diabetic role of Ashwagandha (Withania somnifera) in a type 2 diabetes mellitus mouse model: a study using histological, molecular, and pathological parameters

inferred← citeshttps://doi.org/10.1007/s10068-018-00547-8openalex-snapshot

Ameliorative effects of Lycium chinensis on male sexual dysfunction and testicular oxidative damage in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s10103-017-2160-7openalex-snapshot

Photobiomodulation laser and pulsed electrical field increase the viability of the musculocutaneous flap in diabetic rats

inferred← citeshttps://doi.org/10.1007/s10103-026-04961-xopenalex-snapshot

Comparative biomolecular analysis of normal and healed skin tissue from diabetic and non-diabetic rats using Raman spectroscopy

inferred← citeshttps://doi.org/10.1007/s10517-013-2009-4openalex-snapshot

Role of Nitric Oxide in the Pathogenesis of Alloxan Diabetes

inferred← citeshttps://doi.org/10.1007/s10517-013-2071-yopenalex-snapshot

Dynamics of Lipid Peroxidation—Antioxidant Defense System during Alloxan Diabetes in Rats

inferred← citeshttps://doi.org/10.1007/s10517-013-2079-3openalex-snapshot

Cerebroprotective Effects of Emoxipin, Reamberin, and Mexidol in Alloxan Diabetes

inferred← citeshttps://doi.org/10.1007/s10517-014-2454-8openalex-snapshot

A Study of the Mechanisms for Antiaggregant Activity of Pyrrolidone Derivatives in Rats with Chronic Hyperglycemia

inferred← citeshttps://doi.org/10.1007/s10517-015-2940-7openalex-snapshot

Effect of Nitric Oxide Synthesis Blockade on the Morphology of Langerhans Islets in August and Wistar Rats with Acute Alloxan Diabetes

inferred← citeshttps://doi.org/10.1007/s10517-018-4197-4openalex-snapshot

Effects Mifepristone on Aminotransferase Activities in the Liver in Rats with Streptozotocin-Induced Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/s10522-015-9569-9openalex-snapshot

Effects of ageing and experimental diabetes on insulin-degrading enzyme expression in male rat tissues

inferred← citeshttps://doi.org/10.1007/s10522-019-09849-8openalex-snapshot

Alternative NADH dehydrogenase extends lifespan and increases resistance to xenobiotics in Drosophila

inferred← citeshttps://doi.org/10.1007/s10534-020-00270-0openalex-snapshot

Cardio-protective effects of a dioxidovanadium(V) complex in male sprague–dawley rats with streptozotocin-induced diabetes

inferred← citeshttps://doi.org/10.1007/s10616-011-9414-1openalex-snapshot

Suppressive effects of natural reduced waters on alloxan-induced apoptosis and type 1 diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s10695-020-00769-wopenalex-snapshot

Effects of streptozotocin on pancreatic islet β-cell apoptosis and glucose metabolism in zebrafish larvae

inferred← citeshttps://doi.org/10.1007/s10787-025-01703-3openalex-snapshot

The action of injectable nanodispersion of Bixa orellana (Chronic-in®) on arthritis in diabetic rats: pharmacological and histopathological studies

inferred← citeshttps://doi.org/10.1007/s10787-025-01774-2openalex-snapshot

From receptor to response: dissecting the TLR4 pathway in diabetic neuropathy

inferred← citeshttps://doi.org/10.1007/s10787-026-02125-5openalex-snapshot

Bukiniczia cabulica (Boiss.) Lincz. ameliorate diabetes-induced neuropathy: analgesic, anti-diabetic and anti-neuropathic using enzyme inhibitory, molecular docking and in-vivo studies

inferred← citeshttps://doi.org/10.1007/s10811-022-02839-3openalex-snapshot

Anti-hyperglycemic and antioxidant effect of fucoidan extract from Lessonia trabeculata in alloxan-induced diabetes rats

inferred← citeshttps://doi.org/10.1007/s10856-026-07042-1openalex-snapshot

Chitosan-based nano-encapsulation enhances the anti-diabetic efficacy of Eremina desertorum extract by ameliorating hyperglycemia, oxidative stress, and inflammation in diabetic rats

inferred← citeshttps://doi.org/10.1007/s10973-016-6018-1openalex-snapshot

Synthesis, spectral, thermal and insulin-enhancing properties of oxovanadium(IV) complexes of metformin Schiff-bases

inferred← citeshttps://doi.org/10.1007/s11010-010-0408-7openalex-snapshot

Alloxan reduces amplitude of ventricular myocyte shortening and intracellular Ca2+ without altering L-type Ca2+ current, sarcoplasmic reticulum Ca2+ content or myofilament sensitivity to Ca2+ in Wistar rats

inferred← citeshttps://doi.org/10.1007/s11010-013-1824-2openalex-snapshot

Ameliorating effect of eugenol on hyperglycemia by attenuating the key enzymes of glucose metabolism in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s11010-022-04629-4openalex-snapshot

Therapeutic role of kaempferol and myricetin in streptozotocin-induced diabetes synergistically via modulation in pancreatic amylase, glycogen storage and insulin secretion

inferred← citeshttps://doi.org/10.1007/s11010-026-05659-yopenalex-snapshot

Metabolically induced intestinal inflammation: the role of ER stress and autophagy in a porcine model of diabetes

inferred← citeshttps://doi.org/10.1007/s11011-014-9540-5openalex-snapshot

Insulin reverses anxiety-like behavior evoked by streptozotocin-induced diabetes in mice

inferred← citeshttps://doi.org/10.1007/s11011-015-9719-4openalex-snapshot

Characterization of prefrontal cortex microstructure and antioxidant status in a rat model of neurodegeneration induced by aluminium chloride and multiple low-dose streptozotocin

inferred← citeshttps://doi.org/10.1007/s11011-016-9876-0openalex-snapshot

Sweet old memories: a review of the experimental models of the association between diabetes, senility and dementia

inferred← citeshttps://doi.org/10.1007/s11011-016-9949-0openalex-snapshot

NMR-based metabolomics reveals brain region-specific metabolic alterations in streptozotocin-induced diabetic rats with cognitive dysfunction

inferred← citeshttps://doi.org/10.1007/s11011-018-0320-5openalex-snapshot

Grape seed proanthocyanidin extract and insulin prevents cognitive decline in type 1 diabetic rat by impacting Bcl-2 and Bax in the prefrontal cortex

inferred← citeshttps://doi.org/10.1007/s11011-020-00588-1openalex-snapshot

Optimization of intracerebroventricular streptozotocin dose for the induction of neuroinflammation and memory impairments in rats

inferred← citeshttps://doi.org/10.1007/s11011-020-00598-zopenalex-snapshot

NMR-based metabolomics characterizes metabolic changes in different brain regions of streptozotocin-induced diabetic mice with cognitive decline

inferred← citeshttps://doi.org/10.1007/s11011-021-00897-zopenalex-snapshot

Effect of curcumin nanoparticles on streptozotocin-induced male Wistar rat model of Alzheimer’s disease

inferred← citeshttps://doi.org/10.1007/s11011-023-01255-xopenalex-snapshot

Transient neonatal hyperglycemia induces metabolic shifts in the rat hippocampus: a 1H NMR-based metabolomics analysis

inferred← citeshttps://doi.org/10.1007/s11011-023-01299-zopenalex-snapshot

Alterations of the glutamatergic system in diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s11030-020-10075-5openalex-snapshot

A system-level approach to investigate alloxan-induced toxicity in microtubule-binding protein to lead type 2 diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s11033-025-11275-8openalex-snapshot

Anti-diabetic effect of camel milk and protein hydrolysates in rat model

inferred← citeshttps://doi.org/10.1007/s11055-015-0068-xopenalex-snapshot

Dynamics of the Initial Signs of Experimental Diabetic Encephalopathy

inferred← citeshttps://doi.org/10.1007/s11055-024-01711-wopenalex-snapshot

The anxiolytic, anti-depressive, and antioxidative effects of lemon verbena in rat rendered diabetic by streptozotocin injection

inferred← citeshttps://doi.org/10.1007/s11064-021-03308-yopenalex-snapshot

Clavulanic Acid Attenuating Effect on the Diabetic Neuropathic Pain in Rats

inferred← citeshttps://doi.org/10.1007/s11094-018-1746-0openalex-snapshot

Evaluation of Polyphenol and Flavonoid Profiles and the Antioxidant Effect of Carduus Acanthoides Hydroalcoholic Extract Compared with Vaccinium Myrtillus in an Animal Model of Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/s11094-022-02759-zopenalex-snapshot

Antioxidant Action of Hesperis matronalis L. in Chronic Experimental Diabetes

inferred← citeshttps://doi.org/10.1007/s11094-026-03487-4openalex-snapshot

Assessing the Impact of Jamun (Syzygium cumini) Ethanolic Seed Extraction on Diabetic Rats

inferred← citeshttps://doi.org/10.1007/s11095-011-0435-4openalex-snapshot

Transdermal Insulin Delivery Using Microdermabrasion

inferred← citeshttps://doi.org/10.1007/s11102-009-0178-yopenalex-snapshot

Effects of physical training on serum and pituitary growth hormone contents in diabetic rats

inferred← citeshttps://doi.org/10.1007/s11154-020-09617-xopenalex-snapshot

Modelling gestational diabetes mellitus: large animals hold great promise

inferred← citeshttps://doi.org/10.1007/s11164-015-2266-0openalex-snapshot

Evaluation of in vivo hypoglycemic potential of 4-ethyloxychalcone in alloxan-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s11248-018-0074-1openalex-snapshot

Generation of insulin-deficient piglets by disrupting INS gene using CRISPR/Cas9 system

inferred← citeshttps://doi.org/10.1007/s11302-020-09728-9openalex-snapshot

Electroacupuncture alleviates diabetic neuropathic pain in rats by suppressing P2X3 receptor expression in dorsal root ganglia

inferred← citeshttps://doi.org/10.1007/s11307-010-0406-xopenalex-snapshot

Pancreatic Beta Cell Mass PET Imaging and Quantification with [11C]DTBZ and [18F]FP-(+)-DTBZ in Rodent Models of Diabetes

inferred← citeshttps://doi.org/10.1007/s11307-018-1291-yopenalex-snapshot

Characterization of Brown Adipose Tissue in a Diabetic Mouse Model with Spiral Volumetric Optoacoustic Tomography

inferred← citeshttps://doi.org/10.1007/s11418-022-01675-6openalex-snapshot

Acacetin attenuates the pancreatic and hepatorenal dysfunction in type 2 diabetic rats induced by high-fat diet combined with streptozotocin

inferred← citeshttps://doi.org/10.1007/s11481-012-9428-2openalex-snapshot

Cytokine Modulation is Necessary for Efficacious Treatment of Experimental Neuropathic Pain

inferred← citeshttps://doi.org/10.1007/s11571-020-09571-zopenalex-snapshot

Intranasal insulin administration may be highly effective in improving cognitive function in mice with cognitive dysfunction by reversing brain insulin resistance

inferred← citeshttps://doi.org/10.1007/s11724-012-0278-8openalex-snapshot

Le rat STZ-diabétique: modèle adapté à l’étude de la neuropathie diabétique douloureuse ?

inferred← citeshttps://doi.org/10.1007/s11756-021-00925-4openalex-snapshot

Geraniol ameliorated serum lipid profile and improved antioxidant defense system in pancreas, liver and heart tissues of alloxan-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s11756-023-01363-0openalex-snapshot

Aspartame consumption causes cognitive impairment in streptozotocin-induced diabetic Wistar rats

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