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Streptozotocin and alloxan induce DNA strand breaks and poly(ADP–ribose) synthetase in pancreatic islets

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-1-4684-2325-9openalex-snapshot

The Diabetic Pancreas

inferredcites →https://doi.org/10.1007/978-1-4684-2325-9_18openalex-snapshot

Chemically and Hormonally Induced Diabetes

inferredcites →https://doi.org/10.1007/bf01219511openalex-snapshot

Effects of streptozotocin in vitro on proinsulin biosynthesis, insulin release and ATP content of isolated rat islets of Langerhans

inferredcites →https://doi.org/10.1007/bf01222099openalex-snapshot

Effect of methylxanthines on alloxan inhibition of insulin release

inferredcites →https://doi.org/10.1007/bf02355886openalex-snapshot

Regulation of proinsulin synthesis in pancreatic islets and a new aspect to insulin-dependent diabetes

inferredcites →https://doi.org/10.1007/bf02590750openalex-snapshot

Inhibition by kynurenine metabolites of proinsulin synthesis in isolated pancreatic islets

inferredcites →https://doi.org/10.1016/0005-2787(75)90158-6openalex-snapshot

Stimulation of nuclear poly(adenosine diphosphate-ribose) polymerase activity from HeLa cells by endonucleases

inferredcites →https://doi.org/10.1016/0005-2787(78)90064-3openalex-snapshot

Characterization and comparison of poly(adenosine diphosphoribose) synthesis and DNA synthesis in nucleotide-permeable cells

inferredcites →https://doi.org/10.1016/0005-2787(78)90065-5openalex-snapshot

Relation of poly(adenosine diphosphoribose) synthesis to DNA synthesis and cell growth

inferredcites →https://doi.org/10.1016/0006-291x(80)90762-7openalex-snapshot

Protection by picolinamide, a novel inhibitor of poly (ADP-ribose) synthetase, against both streptozotocin-induced depression of proinsulin synthesis and reduction of NAD content in pancreatic islets

inferredcites →https://doi.org/10.1016/0006-2952(76)90502-5openalex-snapshot

Alloxan-induced diabetes—evidence for hydroxyl radical as a cytotoxic intermediate

inferredcites →https://doi.org/10.1016/0014-4827(75)90371-7openalex-snapshot

Release of template restriction for DNA synthesis by poly ADP(ribose) polymerase during the HeLa cell cycle

inferredcites →https://doi.org/10.1016/0014-5793(73)80656-8openalex-snapshot

Significance of streptozotocin induced nicotinamide‐adenine‐dinucleotide (NAD) degradation in mouse pancreatic islets

inferredcites →https://doi.org/10.1016/0014-5793(75)81080-5openalex-snapshot

Inhibition by somatostatin of insulin release from isolated pancreatic islets

inferredcites →https://doi.org/10.1016/0014-5793(78)80489-xopenalex-snapshot

Poly(ADP‐ribose) polymerase activity in nucleotide permeable cells

inferredcites →https://doi.org/10.1016/0014-5793(78)80627-9openalex-snapshot

Inhibition of poly(ADP‐ribose) polymerase by methylated xanthines and cytokinins

inferredcites →https://doi.org/10.1016/0014-5793(80)81031-3openalex-snapshot

Streptozotocin: mechanisms of action

inferredcites →https://doi.org/10.1016/s0006-291x(75)80205-1openalex-snapshot

Stimulation of poly(ADP-ribose) polymerase activity by the anti-tumour antibiotic, streptozotocin

inferredcites →https://doi.org/10.1016/s0021-9258(18)43723-4openalex-snapshot

Bovine thymus poly(adenosine diphosphate ribose) polymerase. Physical properties and binding to DNA.

inferredcites →https://doi.org/10.1016/s0021-9258(19)68051-8openalex-snapshot

The Fluorometric Measurement of Deoxyribonucleic Acid in Animal Tissues with Special Reference to the Central Nervous System

inferredcites →https://doi.org/10.1016/s0021-9258(19)70491-8openalex-snapshot

Poly(ADP-ribose) synthesis in vitro programmed by damaged DNA. A comparison of DNA molecules containing different types of strand breaks.

inferredcites →https://doi.org/10.1021/bi00543a006openalex-snapshot

Defective poly(adenosine diphosphoribose) synthesis in Xeroderma pigmentosum

inferredcites →https://doi.org/10.1038/283100a0openalex-snapshot

Translational control of proinsulin synthesis by glucose

inferredcites →https://doi.org/10.1038/283593a0openalex-snapshot

(ADP-ribose)n participates in DNA excision repair

inferredcites →https://doi.org/10.1042/bj1540387openalex-snapshot

Poly(adenosine diphosphate ribose) polymerase activity and nicotinamide adenine dinucleotide in differentiating cardiac muscle

inferredcites →https://doi.org/10.1042/bj1820017openalex-snapshot

Superoxide dismutase, catalase and scavengers of hydroxyl radical protect against the toxic action of alloxan on pancreatic islet cells in vitro

inferredcites →https://doi.org/10.1073/pnas.70.11.3200openalex-snapshot

Breakdown of HeLa Cell DNA Mediated by Vaccinia Virus

inferredcites →https://doi.org/10.1111/j.1432-1033.1979.tb04225.xopenalex-snapshot

The Involvement of Poly(ADP‐ribose) Polymerase in the Degradation of NAD Caused by γ‐Radiation and N‐Methyl‐N‐Nitrosourea

inferredcites →https://doi.org/10.2337/diab.21.7.789openalex-snapshot

Pyridine Nucleotide Depletion in Pancreatic Islets Associated with Streptozotocin-induced Diabetes

inferredcites →https://doi.org/10.2337/diab.29.3.213openalex-snapshot

Inhibition of Alloxan Action in Isolated Pancreatic Islets by Superoxide Dismutase, Catalase, and a Metal Chelator

inferredcites →https://doi.org/10.3181/00379727-61-15347openalex-snapshot

Protective Effect of Glutathione and Cysteine Against Alloxan Diabetes in the Rat.

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.5281/zenodo.12685110openalex-extracted

The Role of Abnormal Ketone Bodies During Insulin Deficiency in Streptozotocin Induced Diabetes

inferred← citeshttps://doi.org/10.1002/(sici)1097-4644(20000401)77:1<82::aid-jcb9>3.0.co;2-vopenalex-snapshot

Multiple low-dose and single high-dose treatments with streptozotocin do not generate nitric oxide

inferred← citeshttps://doi.org/10.1002/1097-0142(19860101)57:1<129::aid-cncr2820570126>3.0.co;2-qopenalex-snapshot

Pancreatic polypeptide-secreting islet cell tumor. A follow-up report

inferred← citeshttps://doi.org/10.1002/9780813820637.ch11openalex-snapshot

Type 2 Diabetes Mellitus

inferred← citeshttps://doi.org/10.1002/bies.950020106openalex-snapshot

Molecular basis of experimental diabetes: Degeneration, oncogenesis and regeneration of pancreatic B‐cells of islets of Langerhans

inferred← citeshttps://doi.org/10.1002/cbf.1470openalex-snapshot

Type 1 diabetes: can exercise impair the autoimmune event? The L ‐arginine/glutamine coupling hypothesis

inferred← citeshttps://doi.org/10.1002/dmr.5610020108openalex-snapshot

Experimental reduction of B‐cell mass: Implications for the pathogenesis of diabetes

inferred← citeshttps://doi.org/10.1002/dmr.5610030308openalex-snapshot

Mouse models of insulin dependent diabetes: Low‐dose streptozocin‐induced diabetes and nonobese diabetic (NOD) mice

inferred← citeshttps://doi.org/10.1002/dmr.5610030406openalex-snapshot

Environmental factors and insulin‐dependent diabetes mellitus

inferred← citeshttps://doi.org/10.1002/dmrr.2813openalex-snapshot

Ghrelin mitigates β‐cell mass loss during insulitis in an animal model of autoimmune diabetes mellitus, the BioBreeding/Worcester rat

inferred← citeshttps://doi.org/10.1002/dmrr.472openalex-snapshot

Differentiating between effects of streptozotocin per se and subsequent hyperglycemia on renal function and metabolism in the streptozotocin‐diabetic rat model

inferred← citeshttps://doi.org/10.1002/em.2860060412openalex-snapshot

Role of oxygen radicals in tumor promotion

inferred← citeshttps://doi.org/10.1002/jbt.20117openalex-snapshot

Rutin improves glucose homeostasis in streptozotocin diabetic tissues by altering glycolytic and gluconeogenic enzymes

inferred← citeshttps://doi.org/10.1002/mnfr.201801100openalex-snapshot

Transcriptional Response of White Adipose Tissue to Withdrawal of Vitamin B3

inferred← citeshttps://doi.org/10.1002/ptr.1374openalex-snapshot

Quercetin allievates oxidative stress in streptozotocin‐induced diabetic rats

inferred← citeshttps://doi.org/10.1002/ptr.1440openalex-snapshot

Ferulic acid alleviates lipid peroxidation in diabetic rats

inferred← citeshttps://doi.org/10.1006/abbi.2000.2094openalex-snapshot

Streptozotocin-Induced β-Cell Death Is Independent of Its Inhibition of O-GlcNAcase in Pancreatic Min6 Cells

inferred← citeshttps://doi.org/10.1006/bmme.1997.2622openalex-snapshot

Changes in Plasma Glucose, Insulin, Glucagon, Catecholamine, and Glycogen Contents in Tissues during Development of Alloxan Diabetes Mellitus in Rats

inferred← citeshttps://doi.org/10.1006/exer.2002.1170openalex-snapshot

Early Retinal Damage in Experimental Diabetes: Electroretinographical and Morphological Observations

inferred← citeshttps://doi.org/10.1006/exnr.2002.7990openalex-snapshot

The Role of NADPH Oxidase and Neuronal Nitric Oxide Synthase in Zinc-Induced Poly(ADP-ribose) Polymerase Activation and Cell Death in Cortical Culture

inferred← citeshttps://doi.org/10.1006/jaut.1997.0130openalex-snapshot

Effect of β-Cell Toxins on Genetically Engineered Insulin-Secreting Cells

inferred← citeshttps://doi.org/10.1006/nbdi.2000.0324openalex-snapshot

Poly(ADP-ribose) Polymerase-1 in the Nervous System

inferred← citeshttps://doi.org/10.1006/phrs.2000.0705openalex-snapshot

Protective effect of boldine on oxidative mitochondrial damage in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1006/plas.2001.1553openalex-snapshot

Loss of RecA Function Affects the Ability of Escherichia coli to Maintain Recombinant Plasmids Containing a Ter Site

inferred← citeshttps://doi.org/10.1007/978-1-4612-4112-6_7openalex-snapshot

Okamoto model for B-cell damage: Recent advances

inferred← citeshttps://doi.org/10.1007/978-1-4612-4166-9_6openalex-snapshot

Applications of In Situ Hybridization and Immunocytochemistry for Localization and Quantification of Peptide Gene Expression — A Lesson From Islet Amyloid Polypeptide

inferred← citeshttps://doi.org/10.1007/978-1-4614-4051-2_5openalex-snapshot

Encephalomyocarditis Virus

inferred← citeshttps://doi.org/10.1007/978-1-4615-0135-0_28openalex-snapshot

Recent Advances in Physiological and Pathological Significance of tryptophan-Nad+Metabolites: lessons from insulin-producing pancreatic ß-Cells

inferred← citeshttps://doi.org/10.1007/978-1-4615-0269-2_13openalex-snapshot

The CD38-Cyclic ADP-Ribose Signal System in Pancreatic ß-Cells

inferred← citeshttps://doi.org/10.1007/978-1-4757-0348-1_19openalex-snapshot

Chemically and Hormonally Induced Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/978-1-4899-1819-2_40openalex-snapshot

New Aspects to the Functioning and Regeneration of Pancreatic β-Cells

inferred← citeshttps://doi.org/10.1007/978-1-4899-1819-2_43openalex-snapshot

DNA-Damage and NAD+-Depletion are Initial Events in Oxygen Radical Induced Islet Cell Death

inferred← citeshttps://doi.org/10.1007/978-1-60761-541-5_7openalex-snapshot

Animal Models of Diabetic Retinopathy

inferred← citeshttps://doi.org/10.1007/978-3-319-18741-9_11openalex-snapshot

Rodent Models of Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-319-20797-1_11-1openalex-snapshot

Rodent Models of Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-319-45307-1_6openalex-snapshot

Regulators of Beta-Cell Death and Regeneration

inferred← citeshttps://doi.org/10.1007/978-3-642-57077-3_21openalex-snapshot

Nitric Oxide in the Immunopathogenesis of Type 1 Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-642-70589-2_56openalex-snapshot

Poly(ADP-Ribose) Synthetase Inhibitors Induce Islet B-Cell Regeneration in Partially Depancreatized Rats

inferred← citeshttps://doi.org/10.1007/978-3-642-72691-0_16openalex-snapshot

Rat Models of Non-Insulin-Dependent Diabetes Mellitus: Evidence that Mild Increases in Plasma Glucose Play an Important Role in Pathogenesis

inferred← citeshttps://doi.org/10.1007/978-3-642-72691-0_7openalex-snapshot

Death of the Pancreatic B-Cell

inferred← citeshttps://doi.org/10.1007/978-3-642-75239-1_3openalex-snapshot

Streptozotocin Interactions with Pancreatic β Cells and the Induction of Insulin-Dependent Diabetes

inferred← citeshttps://doi.org/10.1007/978-3-642-83077-8_9openalex-snapshot

Poly(ADP-Ribose) in Inherited Human Diseases and Experimental Disease Models

inferred← citeshttps://doi.org/10.1007/978-3-7091-6346-7_12openalex-snapshot

Traumatic Brain Injury in Mice Deficient in Poly-ADP(Ribose) Polymerase: A Preliminary Report

inferred← citeshttps://doi.org/10.1007/978-4-431-67929-5_1openalex-snapshot

Role of peroxynitrite and poly-(ADP-ribose) synthetase in shock, inflammation, and ischemia-reperfusion injury

inferred← citeshttps://doi.org/10.1007/978-94-017-0726-8_70openalex-snapshot

Changes in the Relevant Test Parameters of 219 Diabetes Patients under the Influence of the So Called “Nordenau - Phenomenon” in the Prospective Observation Procedure

inferred← citeshttps://doi.org/10.1007/bf00265026openalex-snapshot

Assessment of the diabetogenic drugs alloxan and streptozotocin as models for the study of immune defects in diabetic mice

inferred← citeshttps://doi.org/10.1007/bf00265087openalex-snapshot

Effect of nicotinamide therapy upon B-cell function in newly diagnosed Type 1 (insulin-dependent) diabetic patients

inferred← citeshttps://doi.org/10.1007/bf00266846openalex-snapshot

Phosphoenolpyruvate carboxykinase activity patterns in the liver acinus of diabetic and diabetic and estrogen treated rats

inferred← citeshttps://doi.org/10.1007/bf00274256openalex-snapshot

Streptozotocin is not toxic to the human fetal B cell

inferred← citeshttps://doi.org/10.1007/bf00274530openalex-snapshot

A single major gene controls most of the difference in susceptibility to streptozotocin-induced diabetes between C57BL/6J and C3H/HeJ mice

inferred← citeshttps://doi.org/10.1007/bf00282526openalex-snapshot

Streptozotocin, but not alloxan, induces DNA repair synthesis in mouse pancreatic islets in vitro

inferred← citeshttps://doi.org/10.1007/bf00291976openalex-snapshot

Protective effect of 3-aminobenzamide, an inhibitor of poly (ADP-ribose) synthetase, against streptozotocin-induced diabetes

inferred← citeshttps://doi.org/10.1007/bf00400669openalex-snapshot

Blockade of muscarinic transmission increases the frequency of diabetes after low-dose alloxan challenge in the mouse

inferred← citeshttps://doi.org/10.1007/bf00401759openalex-snapshot

Neurotransmitters partially restore glucose sensitivity of insulin and glucagon secretion from perfused streptozotocin-induced diabetic rat pancreas

inferred← citeshttps://doi.org/10.1007/bf00408470openalex-snapshot

Irreversible loss of normal beta-cell regulation by glucose in neonatally streptozotocin diabetic rats

inferred← citeshttps://doi.org/10.1007/bf00418536openalex-snapshot

Islet amyloid polypeptide (amylin) and insulin are differentially expressed in chronic diabetes induced by streptozotocin in rats

inferred← citeshttps://doi.org/10.1007/bf00685335openalex-snapshot

Reversal of acquired cisplatin resistance by nicotinamide in vitro and in vivo

inferred← citeshttps://doi.org/10.1007/bf00710901openalex-snapshot

Alloxan-induced diabetes in the mouse: Time course of pancreatie B-cell destruction as reflected in an increased islet vascular permeability

inferred← citeshttps://doi.org/10.1007/bf01209729openalex-snapshot

Treatment of cultured pancreatic B-cells with streptozotocin induces cell death by apoptosis

inferred← citeshttps://doi.org/10.1007/bf01919538openalex-snapshot

N-Monomethyl-arginine and nicotinamide prevent streptozotocin-induced double strand DNA break formation in pancreatic rat islets

inferred← citeshttps://doi.org/10.1007/bf01960237openalex-snapshot

Effect of niacin/nicotinamide deficiency on the diabetogenic effect of streptozotocin

inferred← citeshttps://doi.org/10.1007/bf02072037openalex-snapshot

Metallothionein in isolated pancreatic islets of mice: Induction by zinc and streptozotocin, a naturally occurring diabetogen

inferred← citeshttps://doi.org/10.1007/bf02427091openalex-snapshot

Comparative interactions of streptozotocin and chlorozotocin with DNA of an insulin-secreting cell line (RINr)

inferred← citeshttps://doi.org/10.1007/bf02427093openalex-snapshot

Long-term effects of exposure of pancreatic islets to nicotinamide in vitro on DNA synthesis, metabolism and B-cell function

inferred← citeshttps://doi.org/10.1007/bf02581385openalex-snapshot

Reduction in blood and urine glucose levels in streptozotocin and alloxan diabetes by phenazine methosulfate

inferred← citeshttps://doi.org/10.1007/bf02617990openalex-snapshot

Use of pancreatic beta cells in culture to identify diabetogenicN-nitroso compounds

inferred← citeshttps://doi.org/10.1007/bf02788225openalex-snapshot

Induction of islet B-cell regeneration in partially pancreatectomized rats by poly(ADP-ribose) synthetase inhibitors

inferred← citeshttps://doi.org/10.1007/bf02788539openalex-snapshot

Long-term effects of alloxan in mice

inferred← citeshttps://doi.org/10.1007/bf02890232openalex-snapshot

Ultrastructural aspects of streptozotocin cytotoxicity on rat pancreatic islets in vitro

inferred← citeshttps://doi.org/10.1007/bf02899565openalex-snapshot

Decrease in insulin-containing secretory granules and mitochondrial gene expression in mouse pancreatic islets maintained in culture following streptozotocin exposure

inferred← citeshttps://doi.org/10.1007/bf02930227openalex-snapshot

Effects of poly (ADP-ribose) synthetase inhibitor on b-cells of a canine pancreas after massive pancreatectomy

inferred← citeshttps://doi.org/10.1007/bf02986008openalex-snapshot

Anti-diabetic agents from medicinal plants inhibitory activity ofSchizonepeta tenuifolia spikes on the diabetogenesis by streptozotocin in mice

inferred← citeshttps://doi.org/10.1007/bf03044962openalex-snapshot

Apoptose—was ist das?

inferred← citeshttps://doi.org/10.1007/bf03258524openalex-snapshot

Nitric Oxide as an Inflammatory Mediator in Insulin-Dependent Diabetes Mellitus

inferred← citeshttps://doi.org/10.1007/bf03347507openalex-snapshot

CD38 autoimmunity: Recent advances and relevance to human diabetes

inferred← citeshttps://doi.org/10.1007/s001090050305openalex-snapshot

Cyclic ADP-ribose-mediated insulin secretion and Reg , regenerating gene

inferred← citeshttps://doi.org/10.1007/s00125-002-0820-yopenalex-snapshot

Effective and selective prevention of retinal leukostasis in streptozotocin-induced diabetic rats using gliclazide

inferred← citeshttps://doi.org/10.1007/s00125-002-0997-0openalex-snapshot

Protection of rat pancreatic islets by potassium channel openers against alloxan, sodium nitroprusside and interleukin-1β mediated suppression—possible involvement of the mitochondrial membrane potential

inferred← citeshttps://doi.org/10.1007/s00125-007-0886-7openalex-snapshot

The mechanisms of alloxan- and streptozotocin-induced diabetes

inferred← citeshttps://doi.org/10.1007/s00125-014-3175-2openalex-snapshot

In vivo activation of the PI3K–Akt pathway in mouse beta cells by the EGFR mutation L858R protects against diabetes

inferred← citeshttps://doi.org/10.1007/s001250050116openalex-snapshot

Irreversible loss of normal beta-cell regulation by glucose in neonatally streptozotocin diabetic rats

inferred← citeshttps://doi.org/10.1007/s001250050854openalex-snapshot

The CD38-cyclic ADP-ribose signalling system in insulin secretion: molecular basis and clinical implications

inferred← citeshttps://doi.org/10.1007/s001250051519openalex-snapshot

Increased O-GlcNAc transferase in pancreas of rats with streptozotocin-induced diabetes

inferred← citeshttps://doi.org/10.1007/s001250051564openalex-snapshot

Relative importance of transport and alkylation for pancreatic beta-cell toxicity of streptozotocin

inferred← citeshttps://doi.org/10.1007/s00204-005-0055-zopenalex-snapshot

Depression of glucose levels and partial restoration of pancreatic β-cell damage by melatonin in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1007/s00210-015-1182-6openalex-snapshot

Renoprotective effect of lansoprazole in streptozotocin-induced diabetic nephropathy in wistar rats

inferred← citeshttps://doi.org/10.1007/s00335-018-9742-yopenalex-snapshot

Congenic mapping and candidate gene analysis for streptozotocin-induced diabetes susceptibility locus on mouse chromosome 11

inferred← citeshttps://doi.org/10.1007/s00428-003-0967-zopenalex-snapshot

Nitric oxide generation and poly(ADP ribose) polymerase activation precede beta-cell death in rats with a single high-dose injection of streptozotocin

inferred← citeshttps://doi.org/10.1007/s00441-018-2903-1openalex-snapshot

Effect of nociceptin on insulin release in normal and diabetic rat pancreas

inferred← citeshttps://doi.org/10.1007/s005340050115openalex-snapshot

The Reg gene family and Reg proteins: with special attention to the regeneration of pancreatic ?-cells

inferred← citeshttps://doi.org/10.1007/s00726-010-0700-6openalex-snapshot

Inhibition of a bacterial O-GlcNAcase homologue by lactone and lactam derivatives: structural, kinetic and thermodynamic analyses

inferred← citeshttps://doi.org/10.1007/s00795-004-0264-1openalex-snapshot

O-GlcNAc modification of nucleocytoplasmic proteins and diabetes

inferred← citeshttps://doi.org/10.1007/s10616-011-9414-1openalex-snapshot

Suppressive effects of natural reduced waters on alloxan-induced apoptosis and type 1 diabetes mellitus

inferred← citeshttps://doi.org/10.1007/s10735-009-9251-0openalex-snapshot

Protective effects of the volatile oil of Nigella sativa seeds on β-cell damage in streptozotocin-induced diabetic rats: a light and electron microscopic study

inferred← citeshttps://doi.org/10.1007/s12272-011-0412-9openalex-snapshot

Synergistic improvement in insulin resistance with a combination of fenofibrate and rosiglitazone in obese type 2 diabetic mice

inferred← citeshttps://doi.org/10.1007/s13410-010-0011-1openalex-snapshot

Hypoglycemic activity of leaves of Acanthus montanus T.Anderson (Acanthaceae) in rats

inferred← citeshttps://doi.org/10.1007/s13596-013-0119-1openalex-snapshot

Renoprotective effects of oryzanol in an animal model of experimentally induced diabetic nephropathy

inferred← citeshttps://doi.org/10.1007/s43994-023-00026-9openalex-snapshot

Protective effect of lactoferrin administration against brain tissue damage in diabetic rats

inferred← citeshttps://doi.org/10.1016/0002-9610(92)90044-ropenalex-snapshot

Untreated diabetes mellitus promotes intestinal microbial overgrowth

inferred← citeshttps://doi.org/10.1016/0003-9861(89)90122-7openalex-snapshot

tert-Butyl hydroperoxide kills cultured hepatocytes by peroxidizing membrane lipids

inferred← citeshttps://doi.org/10.1016/0006-2952(82)90571-8openalex-snapshot

Alloxan toxicity to the pancreatic B-cell

inferred← citeshttps://doi.org/10.1016/0006-2952(91)90230-3openalex-snapshot

Exposure of pancreatic islets to different alkylating agents decreases mitochondrial DNA content but only streptozotocin induces long-lasting functional impairment of B-cells

inferred← citeshttps://doi.org/10.1016/0006-2952(94)90560-6openalex-snapshot

Fusidic acid suppresses nitric oxide toxicity in pancreatic islet cells

inferred← citeshttps://doi.org/10.1016/0006-2952(95)02433-6openalex-snapshot

Potential role of environmental genotoxic agents in diabetes mellitus and neurodegenerative diseases

inferred← citeshttps://doi.org/10.1016/0014-2999(94)90691-2openalex-snapshot

Prevention of diabetes by thymic hormone in alloxan-treated rats

inferred← citeshttps://doi.org/10.1016/0014-5793(82)80187-7openalex-snapshot

Poly(ADP‐ribose) synthetase inhibitors enhance streptozotocin‐induced killing of insulinoma cells by inhibiting the repair of DNA strand breaks

inferred← citeshttps://doi.org/10.1016/0014-5793(95)00401-topenalex-snapshot

Suppression of nitric oxide toxicity in islet cells by α‐tocopherol

inferred← citeshttps://doi.org/10.1016/0020-711x(86)90059-5openalex-snapshot

Influence of streptozotocin upon the induction of tyrosine aminotransferase, the content of NAD and of 5-methyl cytosine in rat liver

inferred← citeshttps://doi.org/10.1016/0024-3205(91)90197-jopenalex-snapshot

Probucol attenuated hyperglycemia in multiple low-dose streptozotocin-induced diabetic mice

inferred← citeshttps://doi.org/10.1016/0024-3205(95)00109-jopenalex-snapshot

Poly(ADP-ribose) synthesis induced by nitric oxide in a mouse β-cell line

inferred← citeshttps://doi.org/10.1016/0024-3205(95)00150-5openalex-snapshot

Hydroxyl radical formation in diabetic rats induced by streptozotocin

inferred← citeshttps://doi.org/10.1016/0024-3205(95)02125-3openalex-snapshot

The effects of nicotinamide and glimepiride on diabetes prevention in BB rats

inferred← citeshttps://doi.org/10.1016/0026-0495(91)90137-lopenalex-snapshot

Neonatal streptozotocin injection: A model of glucotoxicity?

inferred← citeshttps://doi.org/10.1016/0026-0495(92)90055-fopenalex-snapshot

Partial protection of 1α-hydroxyvitamin D3 against the development of diabetes induced by multiple low-dose streptozotocin injection in CD-1 mice

inferred← citeshttps://doi.org/10.1016/0027-5107(94)90235-6openalex-snapshot

Metabolic activation of four drugs in the eye mosaic assay measuring principally mitotic recombination in Drosophila melanogaster: differences in strain susceptibility and route of exposure

inferred← citeshttps://doi.org/10.1016/0041-008x(83)90188-6openalex-snapshot

Characteristics of nicotinamide and N1-methylnicotinamide protection from alloxan diabetes in mice

inferred← citeshttps://doi.org/10.1016/0041-008x(83)90281-8openalex-snapshot

Effects of the rodenticide Vacor on cultured rat pancreatic beta cells

inferred← citeshttps://doi.org/10.1016/0076-6879(88)63031-xopenalex-snapshot

[29] In vitro models for the study of oxidant-induced injury of cells in inflammation

inferred← citeshttps://doi.org/10.1016/0163-7258(89)90008-9openalex-snapshot

Immunological aspects of diabetes mellitus: Prospects for pharmacological modification

inferred← citeshttps://doi.org/10.1016/0165-6147(82)91205-6openalex-snapshot

Baclofen: 10 years on

inferred← citeshttps://doi.org/10.1016/0167-4889(92)90016-5openalex-snapshot

Regulation of mitochondrial glycerol-phosphate dehydrogenase by Ca2+ within electropermeabilized insulin-secreting cells (INS-1)

inferred← citeshttps://doi.org/10.1016/0168-8227(93)90128-ropenalex-snapshot

Nicotinamide, a poly (ADP-ribose) synthetase inhibitor, ameliorates B-cell function in partially depancreatized rats

inferred← citeshttps://doi.org/10.1016/0198-8859(85)90064-3openalex-snapshot

Polymorphic radiation sensitivity of human natural killer activity: Possible role of DNA strand breakage

inferred← citeshttps://doi.org/10.1016/0300-483x(90)90189-nopenalex-snapshot

Disappearance of glucose-induced oscillations of cytoplasmic Ca2+ in pancreatic β-cells exposed to streptozotocin or alloxan

inferred← citeshttps://doi.org/10.1016/0300-9084(96)88146-6openalex-snapshot

New aspects of the physiological significance of NAD, poly ADP-ribose and cyclic ADP-ribose

inferred← citeshttps://doi.org/10.1016/0303-7207(88)90198-0openalex-snapshot

Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations

inferred← citeshttps://doi.org/10.1016/0303-7207(94)90068-xopenalex-snapshot

Nuclear response of pancreatic islets to interleukin-1β

inferred← citeshttps://doi.org/10.1016/0531-5565(94)00036-3openalex-snapshot

Oxygen free radicals, melatonin, and aging

inferred← citeshttps://doi.org/10.1016/0891-5849(88)90036-6openalex-snapshot

Free radicals and diabetes

inferred← citeshttps://doi.org/10.1016/0891-5849(96)00170-0openalex-snapshot

DNA strand breakage and activation of poly-ADP ribosyltransferase: A cytotoxic pathway triggered by peroxynitrite

inferred← citeshttps://doi.org/10.1016/0925-4439(94)90111-2openalex-snapshot

Role of Ca2+ in alloxan-induced pancreatic β-cell damage

inferred← citeshttps://doi.org/10.1016/b978-0-12-415894-8.00009-9openalex-snapshot

Cardiovascular Models

inferred← citeshttps://doi.org/10.1016/b978-0-12-809468-6.00007-3openalex-snapshot

Cardiovascular Models: Heart Secondarily Affected by Disease (Diabetes Mellitus, Renal Failure, Dysfunctional Sympathetic Innervation)

inferred← citeshttps://doi.org/10.1016/b978-0-12-820669-0.00016-5openalex-snapshot

Strategies for the prevention or reversal of neuropathy

inferred← citeshttps://doi.org/10.1016/b978-0-323-90583-1.00034-9openalex-snapshot

Selection of experimental models mimicking human pathophysiology for diabetic microvascular complications

inferred← citeshttps://doi.org/10.1016/b978-0-444-53856-7.00009-9openalex-snapshot

Liver and Pancreas

inferred← citeshttps://doi.org/10.1016/b978-012370420-7/50050-2openalex-snapshot

Cytotoxic Role of Nitric Oxide in Diabetes

inferred← citeshttps://doi.org/10.1016/b978-044450514-9/50008-5openalex-snapshot

Digestive System 2

inferred← citeshttps://doi.org/10.1016/b978-044452771-4/50010-9openalex-snapshot

Liver and Pancreas

inferred← citeshttps://doi.org/10.1016/bs.irn.2019.04.002openalex-snapshot

Role of mitochondria in diabetic peripheral neuropathy: Influencing the NAD+-dependent SIRT1–PGC-1α–TFAM pathway

inferred← citeshttps://doi.org/10.1016/j.abb.2013.03.011openalex-snapshot

Protective effect of nicotinamide on high glucose/palmitate-induced glucolipotoxicity to INS-1 beta cells is attributed to its inhibitory activity to sirtuins

inferred← citeshttps://doi.org/10.1016/j.addr.2021.113904openalex-snapshot

Fibrosis of the diabetic heart: Clinical significance, molecular mechanisms, and therapeutic opportunities

inferred← citeshttps://doi.org/10.1016/j.bbadis.2020.166044openalex-snapshot

Diabetic fibrosis

inferred← citeshttps://doi.org/10.1016/j.bbagen.2009.07.019openalex-snapshot

Structural analyses of enzymes involved in the O-GlcNAc modification

inferred← citeshttps://doi.org/10.1016/j.bbagen.2009.07.028openalex-snapshot

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase

inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.05.198openalex-snapshot

Suppression of SOCS3 expression in the pancreatic β-cell leads to resistance to type 1 diabetes

inferred← citeshttps://doi.org/10.1016/j.bbrc.2008.04.033openalex-snapshot

Transplantation of bone marrow derived cells promotes pancreatic islet repair in diabetic mice

inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.05.065openalex-snapshot

Diabetogenic agent alloxan is a proteasome inhibitor

inferred← citeshttps://doi.org/10.1016/j.bgm.2015.08.001openalex-snapshot

Antidiabetic effects of Eugenia jambolana in the streptozotocin-induced diabetic male albino rat

inferred← citeshttps://doi.org/10.1016/j.biocel.2017.07.009openalex-snapshot

From insulin synthesis to secretion: Alternative splicing of type 2 ryanodine receptor gene is essential for insulin secretion in pancreatic β cells

inferred← citeshttps://doi.org/10.1016/j.biomag.2012.10.002openalex-snapshot

Ameliorative effects quercetin against impaired motor nerve function, inflammatory mediators and apoptosis in neonatal streptozotocin-induced diabetic neuropathy in rats

inferred← citeshttps://doi.org/10.1016/j.biomag.2012.10.006openalex-snapshot

Elucidation of ameliorative effect of Co-enzyme Q10 in streptozotocin-induced diabetic neuropathic perturbation by modulation of electrophysiological, biochemical and behavioral markers

inferred← citeshttps://doi.org/10.1016/j.biomag.2013.10.008openalex-snapshot

Cardioprotective effects of Ficus religiosa in neonatal streptozotocin-induced diabetic cardiomyopathy in rats

inferred← citeshttps://doi.org/10.1016/j.biopha.2016.07.052openalex-snapshot

Antidiabetic assessment; in vivo study of gold and core-shell silver-gold nanoparticles on streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1016/j.biopha.2018.02.137openalex-snapshot

Animal models and natural products to investigate in vivo and in vitro antidiabetic activity

inferred← citeshttps://doi.org/10.1016/j.canlet.2005.10.003openalex-snapshot

Parp-1 deficiency does not increase the frequency of tumors in the oral cavity and esophagus of ICR/129Sv mice by 4-nitroquinoline 1-oxide, a carcinogen producing bulky adducts

inferred← citeshttps://doi.org/10.1016/j.cbi.2004.06.007openalex-snapshot

Protective effect of macrocyclic binuclear oxovanadium complex on oxidative stress in pancreas of streptozotocin induced diabetic rats

inferred← citeshttps://doi.org/10.1016/j.cccn.2005.04.013openalex-snapshot

The effect of age on the enzyme activities of tryptophan metabolism along the kynurenine pathway in rats

inferred← citeshttps://doi.org/10.1016/j.chembiol.2008.06.010openalex-snapshot

Chemical Dissection of the Link between Streptozotocin, O-GlcNAc, and Pancreatic Cell Death

inferred← citeshttps://doi.org/10.1016/j.cmet.2015.05.023openalex-snapshot

NAD+ Metabolism and the Control of Energy Homeostasis: A Balancing Act between Mitochondria and the Nucleus

inferred← citeshttps://doi.org/10.1016/j.colsurfb.2014.07.022openalex-snapshot

Effect of biologically synthesized gold nanoparticles on alloxan-induced diabetic rats—An in vivo approach

inferred← citeshttps://doi.org/10.1016/j.diabres.2010.10.014openalex-snapshot

Evolutionary interactions between diabetes and development

inferred← citeshttps://doi.org/10.1016/j.etp.2011.08.012openalex-snapshot

The potential role of combined antioxidant treatment on pancreas of STZ-diabetic mice

inferred← citeshttps://doi.org/10.1016/j.exppara.2013.08.003openalex-snapshot

Heligmosomoides polygyrus infection reduces severity of type 1 diabetes induced by multiple low-dose streptozotocin in mice via STAT6- and IL-10-independent mechanisms

inferred← citeshttps://doi.org/10.1016/j.exppara.2017.03.008openalex-snapshot

Dual genetic absence of STAT6 and IL-10 does not abrogate anti-hyperglycemic effects of Schistosoma mansoni in streptozotocin-treated diabetic mice

inferred← citeshttps://doi.org/10.1016/j.fct.2014.05.023openalex-snapshot

Taurine ameliorates neuropathy via regulating NF-κB and Nrf2/HO-1 signaling cascades in diabetic rats

inferred← citeshttps://doi.org/10.1016/j.fct.2021.112443openalex-snapshot

Combined treatment of sinapic acid and ellagic acid attenuates hyperglycemia in streptozotocin-induced diabetic rats

inferred← citeshttps://doi.org/10.1016/j.febslet.2005.12.070openalex-snapshot

Cyclin D1 activation through ATF‐2 in Reg‐induced pancreatic β‐cell regeneration

inferred← citeshttps://doi.org/10.1016/j.foodchem.2010.07.104openalex-snapshot

Protective effect of dietary ginger on antioxidant enzymes and oxidative damage in experimental diabetic rat tissues

inferred← citeshttps://doi.org/10.1016/j.ijsu.2014.06.007openalex-snapshot

Allogenous skin fibroblast transplantation enhances excisional wound healing following alloxan diabetes in sheep, a randomized controlled trial

inferred← citeshttps://doi.org/10.1016/j.jare.2018.01.002openalex-snapshot

Arachidonic acid in health and disease with focus on hypertension and diabetes mellitus: A review

inferred← citeshttps://doi.org/10.1016/j.jep.2009.08.037openalex-snapshot

Further evaluation of antihyperglycaemic activity of Hunteria umbellata (K. Schum) Hallier f. seed extract in experimental diabetes

inferred← citeshttps://doi.org/10.1016/j.jep.2011.03.062openalex-snapshot

Identification of trans-tiliroside as active principle with anti-hyperglycemic, anti-hyperlipidemic and antioxidant effects from Potentilla chinesis

inferred← citeshttps://doi.org/10.1016/j.jep.2011.10.009openalex-snapshot

Preliminary study of antidiabetic activity of the methanolic leaf extract of Axonopus compressus (P. Beauv) in alloxan-induced diabetic rats

inferred← citeshttps://doi.org/10.1016/j.jep.2021.113777openalex-snapshot

Pharmacological activity and flavonoids constituents of Artemisia judaica L aerial parts

inferred← citeshttps://doi.org/10.1016/j.jep.2022.115899openalex-snapshot

Hypericum perforatum L. extract exerts insulinotropic effects and inhibits gluconeogenesis in diabetic rats by regulating AMPK expression and PKCε concentration

inferred← citeshttps://doi.org/10.1016/j.jhep.2014.07.018openalex-snapshot

mPGES-2 deletion remarkably enhances liver injury in streptozotocin-treated mice via induction of GLUT2

inferred← citeshttps://doi.org/10.1016/j.jopr.2012.11.035openalex-snapshot

Antidiabetic effect of methanolic extract of Decalepis hamiltonii root (wight and Arn) in normal and alloxan induced diabetic rats

inferred← citeshttps://doi.org/10.1016/j.jopr.2013.07.020openalex-snapshot

Liver protective effects of aqueous extract of Syzygium cumini in Swiss albino mice on alloxan induced diabetes mellitus

inferred← citeshttps://doi.org/10.1016/j.jss.2007.02.044openalex-snapshot

Research of PDGF-BB Gel on the Wound Healing of Diabetic Rats and Its Pharmacodynamics

inferred← citeshttps://doi.org/10.1016/j.jtcme.2017.04.007openalex-snapshot

Evaluation of the antidiabetic property of aqueous leaves extract of Zanthoxylum armatum DC. using in vivo and in vitro approaches

inferred← citeshttps://doi.org/10.1016/j.kint.2016.06.035openalex-snapshot

Cathepsin L is crucial for the development of early experimental diabetic nephropathy

inferred← citeshttps://doi.org/10.1016/j.lfs.2006.07.027openalex-snapshot

Anti-diabetic effects of electrolyzed reduced water in streptozotocin-induced and genetic diabetic mice

inferred← citeshttps://doi.org/10.1016/j.lfs.2021.120062openalex-snapshot

A new mouse model of type 2 diabetes mellitus established through combination of high-fat diet, streptozotocin and glucocorticoid

inferred← citeshttps://doi.org/10.1016/j.lfs.2022.120769openalex-snapshot

Amelioration of oxidative stress mediated inflammation and apoptosis in pancreatic islets by Lupeol in STZ-induced hyperglycaemic mice

inferred← citeshttps://doi.org/10.1016/j.metabol.2020.154402openalex-snapshot

Hyperglycemia-reduced NAD+ biosynthesis impairs corneal epithelial wound healing in diabetic mice

inferred← citeshttps://doi.org/10.1016/j.mrfmmm.2004.11.008openalex-snapshot

Analysis of streptozotocin-induced incomplete chromosome elements and excess acentric fragments in Chinese hamster cells using a telomeric PNA probe

inferred← citeshttps://doi.org/10.1016/j.msec.2018.06.055openalex-snapshot

In-vivo sustained release of nanoencapsulated ferulic acid and its impact in induced diabetes

inferred← citeshttps://doi.org/10.1016/j.nbd.2003.08.008openalex-snapshot

Poly(ADP-ribose) polymerase-1 and apoptosis inducing factor in neurotoxicity

inferred← citeshttps://doi.org/10.1016/j.nucmedbio.2005.03.001openalex-snapshot

Synthesis and in vivo evaluation of [11C]PJ34, a potential radiotracer for imaging the role of PARP-1 in necrosis

inferred← citeshttps://doi.org/10.1016/j.plefa.2004.04.006openalex-snapshot

Effect of prostaglandins against alloxan-induced cytotoxicity to insulin secreting insulinoma RIN cells in vitro

inferred← citeshttps://doi.org/10.1016/j.plefa.2005.09.003openalex-snapshot

Effect of prostaglandins against alloxan-induced diabetes mellitus

inferred← citeshttps://doi.org/10.1016/j.plefa.2005.11.006openalex-snapshot

Differential effect of saturated, monounsaturated, and polyunsaturated fatty acids on alloxan-induced diabetes mellitus

inferred← citeshttps://doi.org/10.1016/j.regpep.2013.07.005openalex-snapshot

Parp1 deficient mice are protected from streptozotocin-induced diabetes but not caerulein-induced pancreatitis, independent of the induction of Reg family genes

inferred← citeshttps://doi.org/10.1016/j.yexcr.2026.114998openalex-snapshot

The antineoplastic agent streptozotocin induces short-term telomere instability in Epstein-Barr virus-transformed human lymphoblastoid cells

inferred← citeshttps://doi.org/10.1016/j.ymthe.2026.02.043openalex-snapshot

Elevated MANF expression in β cells protects mice from streptozotocin-induced diabetes by attenuating islet stress and immunogenicity

inferred← citeshttps://doi.org/10.1016/j.yrtph.2007.09.006openalex-snapshot

Evaluation of streptozotocin genotoxicity in rats from different ages using the micronucleus assay

inferred← citeshttps://doi.org/10.1016/s0006-2952(98)00370-0openalex-snapshot

Site-specific DNA methylation and apoptosis: induction by diabetogenic streptozotocin

inferred← citeshttps://doi.org/10.1016/s0014-2999(98)00249-0openalex-snapshot

Role of poly(ADP-ribose)synthetase in inflammation

inferred← citeshttps://doi.org/10.1016/s0021-9258(18)34226-1openalex-snapshot

Formation and resealing of intercalator-induced DNA strand breaks in permeabilized L1210 cells without the stimulated synthesis of poly(ADP-ribose).

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