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Advances in CNS PET: the state-of-the-art for new imaging targets for pathophysiology and drug development
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inferredcites →https://doi.org/10.1001/archpsyc.57.1.65openalex-snapshot
Decreased Dendritic Spine Density on Prefrontal Cortical Pyramidal Neurons in Schizophrenia
inferredcites →https://doi.org/10.1001/jamaneurol.2014.1954openalex-snapshot
The Phosphodiesterase 10 Positron Emission Tomography Tracer, [18F]MNI-659, as a Novel Biomarker for Early Huntington Disease
inferredcites →https://doi.org/10.1001/jamaneurol.2017.4907openalex-snapshot
Association Between Amyloid and Tau Accumulation in Young Adults With Autosomal Dominant Alzheimer Disease
inferredcites →https://doi.org/10.1002/9781118854754openalex-snapshot
The Chemistry of Molecular Imaging
inferredcites →https://doi.org/10.1002/ana.24546openalex-snapshot
Tau positron emission tomographic imaging in aging and early A lzheimer disease
inferredcites →https://doi.org/10.1002/ana.24711openalex-snapshot
In vivo cortical spreading pattern of tau and amyloid in the Alzheimer disease spectrum
inferredcites →https://doi.org/10.1002/ana.24844openalex-snapshot
Pathological correlations of [F‐18]‐AV‐1451 imaging in non‐alzheimer tauopathies
inferredcites →https://doi.org/10.1002/ana.25060openalex-snapshot
18F‐flortaucipir tau positron emission tomography distinguishes established progressive supranuclear palsy from controls and Parkinson disease: A multicenter study
inferredcites →https://doi.org/10.1002/ana.410300410openalex-snapshot
Physical basis of cognitive alterations in alzheimer's disease: Synapse loss is the major correlate of cognitive impairment
inferredcites →https://doi.org/10.1002/chin.200417232openalex-snapshot
Blood‐Brain Barrier Permeation Models: Discriminating Between Potential CNS and Non‐CNS Drugs Including P‐Glycoprotein Substrates.
inferredcites →https://doi.org/10.1002/chin.200731185openalex-snapshot
Prospects for Metabotropic Glutamate 1 Receptor Antagonists in the Treatment of Neuropathic Pain.
inferredcites →https://doi.org/10.1002/cmdc.201300482openalex-snapshot
Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single‐Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands
inferredcites →https://doi.org/10.1002/gps.2640openalex-snapshot
PET imaging of brain amyloid in dementia: a review
inferredcites →https://doi.org/10.1002/jlcr.3056openalex-snapshot
Development of novel PET probes, [18F]BCPP‐EF, [18F]BCPP‐BF, and [11C]BCPP‐EM for mitochondrial complex 1 imaging in the living brain
inferredcites →https://doi.org/10.1002/jlcr.3206openalex-snapshot
Synthesis and initial preclinical evaluation of the P2X7 receptor antagonist [11C]A‐740003 as a novel tracer of neuroinflammation
inferredcites →https://doi.org/10.1002/mds.27271openalex-snapshot
The tau positron‐emission tomography tracer AV‐1451 binds with similar affinities to tau fibrils and monoamine oxidases
inferredcites →https://doi.org/10.1002/med.20245openalex-snapshot
5‐HT radioligands for human brain imaging with PET and SPECT
inferredcites →https://doi.org/10.1002/med.21432openalex-snapshot
Potential Therapeutic Applications of Adenosine A2AReceptor Ligands and Opportunities for A2AReceptor Imaging
inferredcites →https://doi.org/10.1002/syn.20011openalex-snapshot
Upregulation of striatal adenosine A2A receptor mRNA in 6‐hydroxydopamine‐lesioned rats intermittently treated with L‐DOPA
inferredcites →https://doi.org/10.1002/syn.21541openalex-snapshot
Evaluation and initial in vitro and ex vivo characterization of the potential positron emission tomography ligand, BU99008 (2‐(4,5‐Dihydro‐1H‐imidazol‐2‐yl)‐1‐ methyl‐1H‐indole), for the imidazoline2 binding site
inferredcites →https://doi.org/10.1002/syn.21767openalex-snapshot
Evaluation of the sensitivity of the novel α4β2* nicotinic acetylcholine receptor PET radioligand 18 F‐(‐)‐NCFHEB to increases in synaptic acetylcholine levels in rhesus monkeys
inferredcites →https://doi.org/10.1002/syn.21821openalex-snapshot
Evaluation of a novel PDE 10 A PET radioligand, [11 C ] T ‐773, in nonhuman primates: Brain and whole body PET and brain autoradiography
inferredcites →https://doi.org/10.1002/syn.21840openalex-snapshot
Inhibition of PDE2A, but not PDE9A, modulates presynaptic short‐term plasticity measured by paired‐pulse facilitation in the CA1 region of the hippocampus
inferredcites →https://doi.org/10.1002/syn.21896openalex-snapshot
Brain PET measurement of PDE10A occupancy by TAK‐063, a new PDE10A inhibitor, using [11C]T‐773 in nonhuman primates
inferredcites →https://doi.org/10.1007/s00213-012-2953-0openalex-snapshot
The relationship between antipsychotic D2 occupancy and change in frontal metabolism and working memory
inferredcites →https://doi.org/10.1007/s00213-017-4581-1openalex-snapshot
mGlu1 receptor as a drug target for treatment of substance use disorders: time to gather stones together?
inferredcites →https://doi.org/10.1007/s00259-004-1688-5openalex-snapshot
In vivo imaging of adenosine A2A receptors in rat and primate brain using [11C]SCH442416
inferredcites →https://doi.org/10.1007/s00259-010-1384-6openalex-snapshot
Evaluation of the kappa-opioid receptor-selective tracer [11C]GR103545 in awake rhesus macaques
inferredcites →https://doi.org/10.1007/s00259-010-1686-8openalex-snapshot
Radiosynthesis and in vivo evaluation of a series of substituted 11C-phenethylamines as 5-HT2A agonist PET tracers
inferredcites →https://doi.org/10.1007/s00259-012-2270-1openalex-snapshot
Human biodistribution and dosimetry of 18F-JNJ42259152, a radioligand for phosphodiesterase 10A imaging
inferredcites →https://doi.org/10.1007/s00259-013-2628-zopenalex-snapshot
Evaluation of 18F-BCPP-EF for mitochondrial complex 1 imaging in the brain of conscious monkeys using PET
inferredcites →https://doi.org/10.1007/s00259-013-2681-7openalex-snapshot
In vivo evaluation of a novel tau imaging tracer for Alzheimer’s disease
inferredcites →https://doi.org/10.1007/s00259-014-2821-8openalex-snapshot
Comparing amyloid-β deposition, neuroinflammation, glucose metabolism, and mitochondrial complex I activity in brain: a PET study in aged monkeys
inferredcites →https://doi.org/10.1007/s00259-015-3301-5openalex-snapshot
Metabotropic glutamate receptor 5 – a promising target in drug development and neuroimaging
inferredcites →https://doi.org/10.1007/s00259-016-3349-xopenalex-snapshot
Cholinergic imaging in dementia spectrum disorders
inferredcites →https://doi.org/10.1007/s00259-016-3363-zopenalex-snapshot
Imaging in-vivo tau pathology in Alzheimer’s disease with THK5317 PET in a multimodal paradigm
inferredcites →https://doi.org/10.1007/s00259-016-3544-9openalex-snapshot
Characterization of [11C]Lu AE92686 as a PET radioligand for phosphodiesterase 10A in the nonhuman primate brain
inferredcites →https://doi.org/10.1007/s00259-017-3621-8openalex-snapshot
PET imaging of α7 nicotinic acetylcholine receptors: a comparative study of [18F]ASEM and [18F]DBT-10 in nonhuman primates, and further evaluation of [18F]ASEM in humans
inferredcites →https://doi.org/10.1007/s00259-018-4119-8openalex-snapshot
Quantifying SV2A density and drug occupancy in the human brain using [11C]UCB-J PET imaging and subcortical white matter as reference tissue
inferredcites →https://doi.org/10.1007/s00259-019-04397-2openalex-snapshot
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer’s disease and other tauopathies
inferredcites →https://doi.org/10.1007/s00401-016-1650-1openalex-snapshot
Tau neuropathology correlates with FDG-PET, but not AV-1451-PET, in progressive supranuclear palsy
inferredcites →https://doi.org/10.1007/s00415-016-8248-3openalex-snapshot
Relationship between type 1 metabotropic glutamate receptors and cerebellar ataxia
inferredcites →https://doi.org/10.1007/s11307-014-0779-3openalex-snapshot
Human Brain Imaging of α7 nAChR with [18F]ASEM: a New PET Radiotracer for Neuropsychiatry and Determination of Drug Occupancy
inferredcites →https://doi.org/10.1007/s11307-014-0820-6openalex-snapshot
Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study
inferredcites →https://doi.org/10.1007/s11910-013-0377-9openalex-snapshot
Cholinergic Dysfunction in Parkinson’s Disease
inferredcites →https://doi.org/10.1007/s12017-013-8219-0openalex-snapshot
Increased 5-Methylcytosine and Decreased 5-Hydroxymethylcytosine Levels are Associated with Reduced Striatal A2AR Levels in Huntington’s Disease
inferredcites →https://doi.org/10.1007/s12149-018-1238-zopenalex-snapshot
Open letter to journal editors on: International Consensus Radiochemistry Nomenclature Guidelines
inferredcites →https://doi.org/10.1007/s12350-017-1153-zopenalex-snapshot
Will 18F flurpiridaz replace 82rubidium as the most commonly used perfusion tracer for PET myocardial perfusion imaging?
inferredcites →https://doi.org/10.1007/s13139-017-0484-7openalex-snapshot
Development of tau PET Imaging Ligands and their Utility in Preclinical and Clinical Studies
inferredcites →https://doi.org/10.1007/s13670-018-0234-4openalex-snapshot
Recent Advances in Cholinergic Imaging and Cognitive Decline—Revisiting the Cholinergic Hypothesis of Dementia
inferredcites →https://doi.org/10.1007/s40336-018-00310-3openalex-snapshot
Open letter to journal editors on: International Consensus Radiochemistry Nomenclature Guidelines
inferredcites →https://doi.org/10.1016/0006-3223(94)00252-xopenalex-snapshot
Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia
inferredcites →https://doi.org/10.1016/0014-2999(96)00196-3openalex-snapshot
Imidazoline binding sites in Huntington's and Parkinson's disease putamen
inferredcites →https://doi.org/10.1016/0304-3940(96)12668-9openalex-snapshot
Age, neurofibrillary changes, Aβ-amyloid and the onset of Alzheimer's disease
inferredcites →https://doi.org/10.1016/b978-0-12-418677-4.00004-xopenalex-snapshot
Human Brain Imaging of Opioid Receptors
inferredcites →https://doi.org/10.1016/j.bbabio.2016.02.012openalex-snapshot
Mitochondrial complex I-linked disease
inferredcites →https://doi.org/10.1016/j.bcp.2015.07.030openalex-snapshot
Development of [ 18 F]ASEM, a specific radiotracer for quantification of the α7-nAChR with positron-emission tomography
inferredcites →https://doi.org/10.1016/j.biopsych.2012.01.027openalex-snapshot
Endogenous Opioid Release in the Human Brain Reward System Induced by Acute Amphetamine Administration
inferredcites →https://doi.org/10.1016/j.biopsych.2016.04.012openalex-snapshot
Fatty Acid Amide Hydrolase Binding in Brain of Cannabis Users: Imaging With the Novel Radiotracer [11C]CURB
inferredcites →https://doi.org/10.1016/j.biopsych.2017.02.688openalex-snapshot
962. In-vivo Evidence of Decreased Synaptic Density in Schizophrenia: A [11C]UCB-J PET Imaging Study
inferredcites →https://doi.org/10.1016/j.biopsych.2018.02.1065openalex-snapshot
S173. Evaluation of a Potent and Selective PET Radioligand to Image COX-1 in Human and Nonhuman Primates
inferredcites →https://doi.org/10.1016/j.bmc.2015.05.058openalex-snapshot
Synthesis and biological characterization of a promising F-18 PET tracer for vesicular acetylcholine transporter
inferredcites →https://doi.org/10.1016/j.bmcl.2013.10.014openalex-snapshot
PDE2 inhibition: Potential for the treatment of cognitive disorders
inferredcites →https://doi.org/10.1016/j.brainres.2007.01.079openalex-snapshot
Increase in A2A receptors in the nucleus accumbens after extended cocaine self-administration and its disappearance after cocaine withdrawal
inferredcites →https://doi.org/10.1016/j.cpet.2014.07.005openalex-snapshot
Fluorodeoxyglucose PET in Neurology and Psychiatry
inferredcites →https://doi.org/10.1016/j.dadm.2017.07.001openalex-snapshot
Regional tau deposition and subregion atrophy of medial temporal structures in early Alzheimer's disease: A combined positron emission tomography/magnetic resonance imaging study
inferredcites →https://doi.org/10.1016/j.ddtec.2017.11.003openalex-snapshot
Discovery and development of SV2A PET tracers: Potential for imaging synaptic density and clinical applications
inferredcites →https://doi.org/10.1016/j.ejphar.2009.06.025openalex-snapshot
Autoradiographic comparison of in vitro binding characteristics of various tritiated adenosine A2A receptor ligands in rat, mouse and pig brain and first ex vivo results
inferredcites →https://doi.org/10.1016/j.euroneuro.2006.03.002openalex-snapshot
Antidepressant-like effects of mGluR1 and mGluR5 antagonists in the rat forced swim and the mouse tail suspension tests
inferredcites →https://doi.org/10.1016/j.expneurol.2010.04.004openalex-snapshot
Up-regulation of striatal adenosine A2A receptors with iron deficiency in rats
inferredcites →https://doi.org/10.1016/j.jalz.2012.11.008openalex-snapshot
[ 18 F]T807, a novel tau positron emission tomography imaging agent for Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.jalz.2015.08.013openalex-snapshot
P4‐185: First in‐human PET study of 3 novel tau radiopharmaceuticals: [11C]RO6924963, [11C]RO6931643, and [18F]RO6958948
inferredcites →https://doi.org/10.1016/j.jalz.2016.01.003openalex-snapshot
Characterization of tau positron emission tomography tracer [18F]AV‐1451 binding to postmortem tissue in Alzheimer's disease, primary tauopathies, and other dementias
inferredcites →https://doi.org/10.1016/j.jalz.2016.07.096openalex-snapshot
P4‐351: Evaluation of TAU Burden in a Cross‐Sectional Cohort of Alzheimer’S Disease Subjects Using [18F]GTP1 (GENENTECH TAU PROBE 1)
inferredcites →https://doi.org/10.1016/j.jalz.2016.07.097openalex-snapshot
P4‐352: The Factorial Structure of a Smartphone Based Application Mmse (MMSE‐A) in Japanese Setting
inferredcites →https://doi.org/10.1016/j.jalz.2017.06.1594openalex-snapshot
[P3–378]: FIRST‐IN‐HUMAN PET STUDY WITH 18F‐AM‐PBB3 AND 18F‐PM‐PBB3
inferredcites →https://doi.org/10.1016/j.jns.2015.05.041openalex-snapshot
Decreased metabotropic glutamate receptor type 1 availability in a patient with spinocerebellar ataxia type 6: A 11C-ITMM PET study
inferredcites →https://doi.org/10.1016/j.jns.2017.01.036openalex-snapshot
Comparison of imaging using 11 C-ITMM and 18 F-FDG for the detection of cerebellar ataxia
inferredcites →https://doi.org/10.1016/j.jpsychires.2004.12.008openalex-snapshot
Upregulation of A2A adenosine receptors in platelets from patients affected by bipolar disorders under treatment with typical antipsychotics
inferredcites →https://doi.org/10.1016/j.jpsychires.2013.12.013openalex-snapshot
Reduced striatal adenosine A2A receptor levels define a molecular subgroup in schizophrenia
inferredcites →https://doi.org/10.1016/j.mito.2004.07.028openalex-snapshot
Mitochondrial dysfunction and possible treatments in Parkinson's disease—a review
inferredcites →https://doi.org/10.1016/j.nbd.2013.08.017openalex-snapshot
Translational PET imaging research
inferredcites →https://doi.org/10.1016/j.neubiorev.2009.05.005openalex-snapshot
The dopaminergic basis of human behaviors: A review of molecular imaging studies
inferredcites →https://doi.org/10.1016/j.neulet.2013.08.073openalex-snapshot
Cerebral 5-HT2A receptor binding, but not mGluR2, is increased in tryptophan hydroxylase 2 decrease-of-function mice
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2017.03.022openalex-snapshot
Age and gender effects of 11C-ITMM binding to metabotropic glutamate receptor type 1 in healthy human participants
inferredcites →https://doi.org/10.1016/j.neurobiolaging.2018.01.014openalex-snapshot
Basal forebrain septal nuclei are enlarged in healthy subjects prior to the development of Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.neuroimage.2008.07.022openalex-snapshot
Multitracer PET imaging of amyloid plaques and neurofibrillary tangles in Alzheimer's disease
inferredcites →https://doi.org/10.1016/j.neuroimage.2011.12.037openalex-snapshot
PET radiotracers for molecular imaging in the brain: Past, present and future
inferredcites →https://doi.org/10.1016/j.neuroimage.2013.04.123openalex-snapshot
Preclinical evaluation of [18F]JNJ42259152 as a PET tracer for PDE10A
inferredcites →https://doi.org/10.1016/j.neuroimage.2013.08.035openalex-snapshot
Characterization of [11C]Cimbi-36 as an agonist PET radioligand for the 5-HT2A and 5-HT2C receptors in the nonhuman primate brain
inferredcites →https://doi.org/10.1016/j.neuroimage.2014.05.033openalex-snapshot
Evaluation of the agonist PET radioligand [11C]GR103545 to image kappa opioid receptor in humans: Kinetic model selection, test–retest reproducibility and receptor occupancy by the antagonist PF-04455242
inferredcites →https://doi.org/10.1016/j.neuroimage.2016.02.001openalex-snapshot
Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36: Test–retest reproducibility and head-to-head comparison with the antagonist [18F]altanserin
inferredcites →https://doi.org/10.1016/j.neuroimage.2016.06.047openalex-snapshot
A human [ 11 C]T-773 PET study of PDE10A binding after oral administration of TAK-063, a PDE10A inhibitor
inferredcites →https://doi.org/10.1016/j.neuroimage.2017.02.047openalex-snapshot
Patterns of age related changes for phosphodiesterase type-10A in comparison with dopamine D 2/3 receptors and sub-cortical volumes in the human basal ganglia: A PET study with 18 F-MNI-659 and 11 C-raclopride with correction for partial volume effect
inferredcites →https://doi.org/10.1016/j.neuron.2013.07.037openalex-snapshot
Imaging of Tau Pathology in a Tauopathy Mouse Model and in Alzheimer Patients Compared to Normal Controls
inferredcites →https://doi.org/10.1016/j.neuron.2016.01.028openalex-snapshot
PET Imaging of Tau Deposition in the Aging Human Brain
inferredcites →https://doi.org/10.1016/j.neuropharm.2004.08.007openalex-snapshot
JNJ16259685, a highly potent, selective and systemically active mGlu1 receptor antagonist
inferredcites →https://doi.org/10.1016/j.neuropharm.2005.05.010openalex-snapshot
Anticonvulsant effects of LY456236, a selective mGlu1 receptor antagonist
inferredcites →https://doi.org/10.1016/j.neuropharm.2017.01.016openalex-snapshot
In vivo measurement of PDE10A enzyme occupancy by positron emission tomography (PET) following single oral dose administration of PF-02545920 in healthy male subjects
inferredcites →https://doi.org/10.1016/j.neuroscience.2016.05.028openalex-snapshot
Activation of the adenosine A2A receptor attenuates experimental autoimmune encephalomyelitis and is associated with increased intracellular calcium levels
inferredcites →https://doi.org/10.1016/j.nucmedbio.2009.02.007openalex-snapshot
Positron emission tomography imaging of (2R,3R)-5-[18F]fluoroethoxybenzovesamicol in rat and monkey brain: a radioligand for the vesicular acetylcholine transporter
inferredcites →https://doi.org/10.1016/j.nucmedbio.2010.08.001openalex-snapshot
[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography
inferredcites →https://doi.org/10.1016/j.nucmedbio.2016.10.005openalex-snapshot
A useful PET probe [11C]BU99008 with ultra-high specific radioactivity for small animal PET imaging of I2-imidazoline receptors in the hypothalamus
inferredcites →https://doi.org/10.1016/j.pneurobio.2016.03.007openalex-snapshot
How serotonin receptors regulate morphogenic signalling in neurons
inferredcites →https://doi.org/10.1016/j.pnpbp.2011.10.015openalex-snapshot
Treadmill running frequency on anxiety and hippocampal adenosine receptors density in adult and middle-aged rats
inferredcites →https://doi.org/10.1016/j.pscychresns.2009.03.007openalex-snapshot
Regional distribution and behavioral correlates of 5-HT2A receptors in Alzheimer's disease with [18F]deuteroaltanserin and PET
inferredcites →https://doi.org/10.1016/j.trci.2017.08.004openalex-snapshot
Measuring brain synaptic vesicle protein 2A with positron emission tomography and [ 18 F]UCB‐H
inferredcites →https://doi.org/10.1016/s0002-9343(98)00091-6openalex-snapshot
Cyclooxygenase-1 and Cyclooxygenase-2 Selectivity of Widely Used Nonsteroidal Anti-Inflammatory Drugs
inferredcites →https://doi.org/10.1016/s0006-8993(00)03302-3openalex-snapshot
μ-, δ- and κ-opioid receptor populations are differentially altered in distinct areas of postmortem brains of Alzheimer’s disease patients
inferredcites →https://doi.org/10.1016/s0197-0186(96)00032-0openalex-snapshot
Densities of I2-imidazoline receptors, α2-adrenoceptors and monoamine oxidase B in brains of suicide victims
inferredcites →https://doi.org/10.1016/s0197-0186(96)00043-5openalex-snapshot
Chronic imipramine treatment upregulates IR2-imidazoline receptive sites in rat brain
inferredcites →https://doi.org/10.1016/s0197-4580(97)00037-7openalex-snapshot
Age-Related Increases in Brain Monoamine Oxidase B in Living Healthy Human Subjects
inferredcites →https://doi.org/10.1016/s0304-3940(03)00221-0openalex-snapshot
The striopallidal pathway is involved in antiparkinsonian-like effects of the blockade of group I metabotropic glutamate receptors in rats
inferredcites →https://doi.org/10.1016/s0304-3940(98)00265-1openalex-snapshot
Imidazoline receptor proteins in brains of patients with Alzheimer's disease
inferredcites →https://doi.org/10.1016/s0306-4522(98)00251-6openalex-snapshot
Expression of mu, kappa, and delta opioid receptor messenger RNA in the human CNS: a 33P in situ hybridization study
inferredcites →https://doi.org/10.1016/s0891-0618(01)00117-xopenalex-snapshot
Laminar distribution of nicotinic receptor subtypes in cortical regions in schizophrenia
inferredcites →https://doi.org/10.1016/s1474-4422(12)70291-0openalex-snapshot
Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers
inferredcites →https://doi.org/10.1016/s2215-0366(15)00505-2openalex-snapshot
Estimating the true global burden of mental illness
inferredcites →https://doi.org/10.1017/s0033291718003057openalex-snapshot
Neuroinflammation in schizophrenia: meta-analysis of in vivo microglial imaging studies
inferredcites →https://doi.org/10.1017/s1461145705005055openalex-snapshot
Patients with obsessive–compulsive disorder have increased 5-HT2A receptor binding in the caudate nuclei
inferredcites →https://doi.org/10.1017/s1461145706006559openalex-snapshot
Cerebral 5-HT2A receptor binding is increased in patients with Tourette's syndrome
inferredcites →https://doi.org/10.1021/acs.bioconjchem.7b00243openalex-snapshot
New Trends and Current Status of Positron-Emission Tomography and Single-Photon-Emission Computerized Tomography Radioligands for Neuronal Serotonin Receptors and Serotonin Transporter
inferredcites →https://doi.org/10.1021/acs.jmedchem.6b00166openalex-snapshot
Discovery of 6-(Fluoro- 18 F )-3-(1 H -pyrrolo[2,3- c ]pyridin-1-yl)isoquinolin-5-amine ([ 18 F]-MK-6240): A Positron Emission Tomography (PET) Imaging Agent for Quantification of Neurofibrillary Tangles (NFTs)
inferredcites →https://doi.org/10.1021/acschemneuro.5b00066openalex-snapshot
Kinetic Analysis and Quantification of [11C]Martinostat for in Vivo HDAC Imaging of the Brain
inferredcites →https://doi.org/10.1021/acschemneuro.6b00268openalex-snapshot
Fluorine-18-Labeled Antagonist for PET Imaging of Kappa Opioid Receptors
inferredcites →https://doi.org/10.1021/acschemneuro.8b00102openalex-snapshot
3-Substituted 1,5-Diaryl-1H-1,2,4-triazoles as Prospective PET Radioligands for Imaging Brain COX-1 in Monkey. Part 1: Synthesis and Pharmacology
inferredcites →https://doi.org/10.1021/acsmedchemlett.6b00514openalex-snapshot
Potential Treatment of Cognitive Impairment in Schizophrenia by Phosphodiesterase 2 (PDE2) Inhibitors
inferredcites →https://doi.org/10.1021/ar500233sopenalex-snapshot
A Philosophy for CNS Radiotracer Design
inferredcites →https://doi.org/10.1021/cb500560hopenalex-snapshot
Chemical Modulation of Mutant mGlu 1 Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics
inferredcites →https://doi.org/10.1021/ci034205dopenalex-snapshot
Blood-Brain Barrier Permeation Models: Discriminating between Potential CNS and Non-CNS Drugs Including P-Glycoprotein Substrates
inferredcites →https://doi.org/10.1021/jm060950gopenalex-snapshot
Prospects for Metabotropic Glutamate 1 Receptor Antagonists in the Treatment of Neuropathic Pain
inferredcites →https://doi.org/10.1021/jm201136zopenalex-snapshot
Structural Modifications that Alter the P-Glycoprotein Efflux Properties of Compounds
inferredcites →https://doi.org/10.1021/jm201590gopenalex-snapshot
Synthesis and Evaluation of Novel Radioligands for Positron Emission Tomography Imaging of Metabotropic Glutamate Receptor Subtype 1 (mGluR1) in Rodent Brain
inferredcites →https://doi.org/10.1021/jm401184fopenalex-snapshot
Derivatives of Dibenzothiophene for Positron Emission Tomography Imaging of α7-Nicotinic Acetylcholine Receptors
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Synthesis and Evaluation in Monkey of [18F]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([18F]FIMX): A Promising Radioligand for PET Imaging of Brain Metabotropic Glutamate Receptor 1 (mGluR1)
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In Vivo Imaging of Histone Deacetylases (HDACs) in the Central Nervous System and Major Peripheral Organs
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CNS Drug Design: Balancing Physicochemical Properties for Optimal Brain Exposure
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Discovery of MK-3168: A PET Tracer for Imaging Brain Fatty Acid Amide Hydrolase
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Mapping Human Brain Fatty Acid Amide Hydrolase Activity with PET
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Kinetic Modeling of 11 C-LY2795050, A Novel Antagonist Radiotracer for PET Imaging of the Kappa Opioid Receptor in Humans
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Blocking of Fatty Acid Amide Hydrolase Activity with PF-04457845 in Human Brain: A Positron Emission Tomography Study with the Novel Radioligand [ 11 C]CURB
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A2A adenosine receptor deletion is protective in a mouse model of Tauopathy
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Imaging Synaptic Neurotransmission with in Vivo Binding Competition Techniques: A Critical Review
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Graft-Infiltrating Macrophages Adopt an M2 Phenotype and Are Inhibited by Purinergic Receptor P2X7 Antagonist in Chronic Rejection
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Fatty Acid Amide Hydrolase Inhibition by JNJ‐42165279: A Multiple‐Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers
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Hippocampal α7 nicotinic acetylcholine receptor levels in patients with schizophrenia, bipolar disorder, or major depressive disorder
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Functional Studies of Specific Imidazoline‐2 Receptor Ligands
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Abnormal Metabotropic Glutamate Receptor Expression and Signaling in the Cerebral Cortex in Diffuse Lewy Body Disease is Associated with Irregular α‐Synuclein/Phospholipase C (PLCβ1) Interactions
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Adenosine A2AReceptors are Up‐regulated in Pick’s Disease Frontal Cortex
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Kinetic modeling of [18F]V AT , a novel radioligand for positron emission tomography imaging vesicular acetylcholine transporter in non‐human primate brain
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Receptor Occupancy of the κ-Opioid Antagonist LY2456302 Measured with Positron Emission Tomography and the Novel Radiotracer 11C-LY2795050
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Contrasting effects of chronic lithium, haloperidol and olanzapine exposure on synaptic clusters in the rat prefrontal cortex
inferred← citeshttps://doi.org/10.1101/2021.07.08.451713openalex-snapshot
caliPER: A software for blood-free parametri c P a t l ak mapp i ng using PE T/M R I input function
inferred← citeshttps://doi.org/10.1101/2025.01.26.634877openalex-snapshot
Isostere 18 F-protein post-translational editing enables dynamic tracking of neurodegeneration biomarkers
inferred← citeshttps://doi.org/10.1111/jnc.15516openalex-snapshot
The role of neuroimaging in Parkinson’s disease
inferred← citeshttps://doi.org/10.1111/jnc.15615openalex-snapshot
Beyond monoamines: I. Novel targets and radiotracers for Positron emission tomography imaging in psychiatric disorders
inferred← citeshttps://doi.org/10.1177/0271678x20910038openalex-snapshot
Advances in simultaneous PET/MR for imaging neuroreceptor function
inferred← citeshttps://doi.org/10.1177/0271678x211015101openalex-snapshot
Reproducibility of findings in modern PET neuroimaging: insight from the NRM2018 grand challenge
inferred← citeshttps://doi.org/10.1186/s40035-023-00362-0openalex-snapshot
Defective lysosomal acidification: a new prognostic marker and therapeutic target for neurodegenerative diseases
inferred← citeshttps://doi.org/10.1186/s40658-022-00440-8openalex-snapshot
Performance evaluation of the IRIS XL-220 PET/CT system, a new camera dedicated to non-human primates
inferred← citeshttps://doi.org/10.1186/s40658-025-00803-xopenalex-snapshot
Human subject study of a transmission-aided attenuation correction for precision PET neuroimaging
inferred← citeshttps://doi.org/10.1186/s41181-025-00327-wopenalex-snapshot
Synthesis and in vitro evaluation of spirobenzovesamicols as potential 11C-PET tracer alternatives to [18F]FEOBV for vesicular acetylcholine transporter (VAChT) imaging
inferred← citeshttps://doi.org/10.1248/cpb.c22-00770openalex-snapshot
Synthesis and Characterization of Novel Radioiodinated Triazole-Pyrolidine Derivative to Detect Orexin 2 Receptor in the Brain
inferred← citeshttps://doi.org/10.15252/embj.2021107757openalex-snapshot
A genetically targeted reporter for PET imaging of deep neuronal circuits in mammalian brains
inferred← citeshttps://doi.org/10.2174/0118715230437703251219204750openalex-snapshot
Immunomodulatory Nanocarriers in Multiple Sclerosis: Dual Targeting of Microglia and Mitochondria for Precision Neurotherapy
inferred← citeshttps://doi.org/10.2174/1573405618666220321122214openalex-snapshot
FDG-PET/CT Assessment of the Cerebral Protective Effects of Hydrogen in Rabbits with Cardiac Arrest
inferred← citeshttps://doi.org/10.2967/jnumed.125.270047openalex-snapshot
18 F-FPP-RGD 2 PET Imaging for Interrogating Target Engagement and Antifibrotic Activity of an Integrin Antagonist in a Mouse Model of Metabolic Dysfunction–Associated Steatohepatitis
inferred← citeshttps://doi.org/10.3233/jad-230127openalex-snapshot
Concomitant Neuronal Tau Deposition and FKBP52 Decrease Is an Early Feature of Different Human and Experimental Tauopathies
inferred← citeshttps://doi.org/10.3389/fmed.2022.812270openalex-snapshot
PET Molecular Imaging in Drug Development: The Imaging and Chemistry Perspective
inferred← citeshttps://doi.org/10.3389/fmed.2024.1347267openalex-snapshot
The development process of ‘fit-for-purpose’ imaging biomarkers to characterize the tumor microenvironment
inferred← citeshttps://doi.org/10.3389/fnagi.2020.00227openalex-snapshot
Progress of RAGE Molecular Imaging in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3389/fnins.2022.806876openalex-snapshot
Positron Emission Tomography in the Neuroimaging of Autism Spectrum Disorder: A Review
inferred← citeshttps://doi.org/10.3389/fonc.2021.698425openalex-snapshot
Molecular Imaging and the PD-L1 Pathway: From Bench to Clinic
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.886918openalex-snapshot
Glutamatergic System in Depression and Its Role in Neuromodulatory Techniques Optimization
inferred← citeshttps://doi.org/10.3390/biom13091405openalex-snapshot
Peering into the Brain’s Estrogen Receptors: PET Tracers for Visualization of Nuclear and Extranuclear Estrogen Receptors in Brain Disorders
inferred← citeshttps://doi.org/10.3390/biomedicines10020305openalex-snapshot
Neuroimaging of Mouse Models of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3390/brainsci12091146openalex-snapshot
Molecular Imaging in Parkinsonian Disorders—What’s New and Hot?
inferred← citeshttps://doi.org/10.3390/cells9122581openalex-snapshot
Novel PET Biomarkers to Disentangle Molecular Pathways across Age-Related Neurodegenerative Diseases
inferred← citeshttps://doi.org/10.3390/ijms23095023openalex-snapshot
Radiopharmaceuticals for PET and SPECT Imaging: A Literature Review over the Last Decade
inferred← citeshttps://doi.org/10.3390/ijms232415481openalex-snapshot
Oxidation-Cyclisation of Biphenyl Thioethers to Dibenzothiophenium Salts for Ultrarapid 18F-Labelling of PET Tracers
inferred← citeshttps://doi.org/10.3390/jcm14134439openalex-snapshot
The Future of PET Imaging in Multiple Sclerosis: Characterisation of Individual White Matter Lesions
inferred← citeshttps://doi.org/10.3390/jimaging8020021openalex-snapshot
Monte Carlo Characterization of the Trimage Brain PET System
inferred← citeshttps://doi.org/10.3390/molecules25174017openalex-snapshot
PET Radiotracers for CNS-Adrenergic Receptors: Developments and Perspectives
inferred← citeshttps://doi.org/10.3390/molecules26113208openalex-snapshot
Progress in PET Imaging of Neuroinflammation Targeting COX-2 Enzyme
inferred← citeshttps://doi.org/10.3390/molecules27103173openalex-snapshot
Synthesis, Biological Evaluation, and Docking Studies of Antagonistic Hydroxylated Arecaidine Esters Targeting mAChRs
inferred← citeshttps://doi.org/10.3390/ph14060530openalex-snapshot
Update on PET Tracer Development for Muscarinic Acetylcholine Receptors
inferred← citeshttps://doi.org/10.3390/ph14090847openalex-snapshot
Alpha-Synuclein PET Tracer Development—An Overview about Current Efforts
inferred← citeshttps://doi.org/10.3390/ph15020248openalex-snapshot
Design, Synthesis, and Biological Evaluation of 4,4’-Difluorobenzhydrol Carbamates as Selective M1 Antagonists
inferred← citeshttps://doi.org/10.3390/ph15050516openalex-snapshot
Quantitation of the A2A Adenosine Receptor Density in the Striatum of Mice and Pigs with [18F]FLUDA by Positron Emission Tomography
inferred← citeshttps://doi.org/10.3390/ph15101272openalex-snapshot
Radiosynthesis and Preclinical Evaluation of an 18F-Labeled Triazolopyridopyrazine-Based Inhibitor for Neuroimaging of the Phosphodiesterase 2A (PDE2A)
inferred← citeshttps://doi.org/10.5059/yukigoseikyokaishi.80.1044openalex-snapshot
Development of Specific PET Tracers for Central Nervous System Drug Targets
inferred← citeshttps://doi.org/10.5772/intechopen.106825openalex-snapshot
Positron Emission Tomography in the Neuroimaging of Autism Spectrum Disorder
inferred← citeshttps://doi.org/10.70675/49dea218z7417z4d53z920az487eab265af7openalex-snapshot
Nouvelles approches de criblages haut débit pour la découverte de radioligands de fibres protéiques impliquées dans les maladies neurodégénératives
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