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Human hepatic stellate cell isolation and characterization

https://doi.org/10.1007/s00535-017-1404-4

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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“Sternzellen” in the liver: Perisinusoidal cells with special reference to storage of vitamin A

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Neuroregulation of the neuroendocrine compartment of the liver

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Nonparenchymal Cells Cultivated from Explants of Fibrotic Liver Resemble Endothelial and Smooth Muscle Cells from Blood Vessel Walls†

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The Role of Fat-Storing Cells in Disse Space Fibrogenesis in Alcoholic Liver Disease

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Immunocytochemical Detection of Desmin in Fat-Storing Cells (Ito Cells)

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Isolated hepatic lipocytes and kupffer cells from normal human liver: Morphological and functional characteristics in primary culture

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Confocal microscopy immunofluorescence localization of desmin and other intermediate filament proteins in fetal rat livers

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Mitogenic effect of transforming growth factor-β1 on human Ito cells in culture: Evidence for mediation by endogenous platelet-derived growth factor

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Expression of platelet-derived growth factor in a model of acute liver injury†

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Recent advances in the isolation of liver cells

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Effect of simvastatin, an inhibitor of hydroxy-methylglutaryl coenzyme a reductase, on the growth of human ito cells

inferredcites →https://doi.org/10.1002/hep.1840210136openalex-snapshot

Transforming growth factor-β1 regulates platelet-derived growth factor receptor β subunit in human liver fat-storing cells

inferredcites →https://doi.org/10.1002/hep.1840220315openalex-snapshot

Human myofibroblastlike cells obtained by outgrowth are representative of the fibrogenic cells in the liver

inferredcites →https://doi.org/10.1002/hep.20488openalex-snapshot

Inhibition of T–Cell Responses by Hepatic Stellate Cells Via B7–H1-Mediated T–Cell Apoptosis in Mice

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p75 neurotrophin receptor signaling regulates hepatic myofibroblast proliferation and apoptosis in recovery from rodent liver fibrosis†

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Septum Transversum-Derived Mesothelium Gives Rise to Hepatic Stellate Cells and Perivascular Mesenchymal Cells in Developing Mouse Liver §Δ

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Protease-activated receptor 2 promotes experimental liver fibrosis in mice and activates human hepatic stellate cells

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A novel murine model to deplete hepatic stellate cells uncovers their role in amplifying liver damage in mice

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Purification of rat hepatic stellate cells by side scatter-activated cell sorting

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Class Vi Intermediate Filament Protein Nestin Is Induced During Activation of Rat Hepatic Stellate Cells

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Fibroblast Activation Protein: A Cell Surface Dipeptidyl Peptidase and Gelatinase Expressed by Stellate Cells At the Tissue Remodelling Interface in Human Cirrhosis

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Immunohistochemical identification of Ito cells and their myofibroblastic transformation in adult human liver

inferredcites →https://doi.org/10.1007/bf01308606openalex-snapshot

?-Smooth-muscle actin expression in normal and fibrotic human livers

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Ueber Sternzellen der Leber

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Thy-1 is expressed in myofibroblasts but not found in hepatic stellate cells following liver injury

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Vinculin and cellular retinol-binding protein-1 are markers for quiescent and activated hepatic stellate cells in formalin-fixed paraffin embedded human liver

inferredcites →https://doi.org/10.1007/s004410050524openalex-snapshot

Expression of neural cell adhesion molecule (N-CAM) in perisinusoidal stellate cells of the human liver

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Isolation and culture of hepatic lipocytes, Kupffer cells, and sinusoidal endothelial cells by density gradient centrifugation with Stractan

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Fat-storing cells of the rat liver Their isolation and purification

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Differential expression of platelet-derived growth factor α- and β-receptors on fat-storing cells and endothelial cells of rat liver

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Regulation of extracellular matrix synthesis by transforming growth factor β1 in human fat-storing cells

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Nerves and perisinusoidal cells in human liver

inferredcites →https://doi.org/10.1016/j.bbalip.2008.11.001openalex-snapshot

Hepatic stellate cell lipid droplets: A specialized lipid droplet for retinoid storage

inferredcites →https://doi.org/10.1016/j.bbalip.2016.10.013openalex-snapshot

Hepatic stellate cells retain the capacity to synthesize retinyl esters and to store neutral lipids in small lipid droplets in the absence of LRAT

inferredcites →https://doi.org/10.1016/j.bbrc.2006.09.069openalex-snapshot

PPARγ agonists prevent TGFβ1/Smad3-signaling in human hepatic stellate cells

inferredcites →https://doi.org/10.1016/j.cbi.2006.05.006openalex-snapshot

Human liver slices as an in vitro model to study toxicity-induced hepatic stellate cell activation in a multicellular milieu

inferredcites →https://doi.org/10.1016/j.jhep.2003.12.006openalex-snapshot

On the origin of stellate cells: mesodermal, endodermal or neuro-ectodermal?

inferredcites →https://doi.org/10.1016/j.jhep.2005.01.028openalex-snapshot

Generation of a monoclonal human single chain antibody fragment to hepatic stellate cells – a potential mechanism for targeting liver anti-fibrotic therapeutics

inferredcites →https://doi.org/10.1016/j.jhep.2005.09.023openalex-snapshot

Hepatic stellate cells do not derive from the neural crest

inferredcites →https://doi.org/10.1016/j.jhep.2006.08.013openalex-snapshot

Fibrogenic cell fate during fibrotic tissue remodelling observed in rat and human cultured liver slices

inferredcites →https://doi.org/10.1016/j.lfs.2005.10.003openalex-snapshot

Immunosuppressant FK506 inhibits matrix metalloproteinase-9 induction in TNF-α-stimulated human hepatic stellate cells

inferredcites →https://doi.org/10.1016/j.mam.2007.09.002openalex-snapshot

Myofibroblast – like cells and liver fibrogenesis: Emerging concepts in a rapidly moving scenario

inferredcites →https://doi.org/10.1016/s0002-9440(10)64994-2openalex-snapshot

Hepatic Stellate Cells Express the Low Affinity Nerve Growth Factor Receptor p75 and Undergo Apoptosis in Response to Nerve Growth Factor Stimulation

inferredcites →https://doi.org/10.1016/s0002-9440(10)65501-0openalex-snapshot

Synaptophysin: A Novel Marker for Human and Rat Hepatic Stellate Cells

inferredcites →https://doi.org/10.1016/s0016-5085(71)80118-xopenalex-snapshot

Tissue Culture of Adult Human Liver

inferredcites →https://doi.org/10.1016/s0165-5728(85)80073-4openalex-snapshot

Extra-neural glial fibrillary acidic protein (GFAP) immunoreactivity in perisinusoidal stellate cells of rat liver

inferredcites →https://doi.org/10.1016/s0167-4781(02)00477-3openalex-snapshot

Characterization of human stellate cell activation-associated protein and its expression in human liver

inferredcites →https://doi.org/10.1016/s0168-8278(01)00122-2openalex-snapshot

Alpha B-crystallin expression in human and rat hepatic stellate cells

inferredcites →https://doi.org/10.1016/s0168-8278(01)00260-4openalex-snapshot

Hepatic stellate cell/myofibroblast subpopulations in fibrotic human and rat livers

inferredcites →https://doi.org/10.1016/s0168-8278(02)00263-5openalex-snapshot

Beauty is in the eye of the beholder: emerging concepts and pitfalls in hepatic stellate cell research

inferredcites →https://doi.org/10.1016/s0168-8278(86)80047-2openalex-snapshot

Perisinusoidal cells in patients with normal liver histology

inferredcites →https://doi.org/10.1016/s1056-8719(03)00042-xopenalex-snapshot

Organotypic liver culture in a fluid-air interface using slices of neonatal rat and adult human tissue—a model of fibrosis in vitro

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Proteomic analysis of extracellular matrix from the hepatic stellate cell line LX-2 identifies CYR61 and Wnt-5a as novel constituents of fibrotic liver

inferredcites →https://doi.org/10.1034/j.1600-0676.2002.01503.xopenalex-snapshot

Intrahepatic expression of the hepatic stellate cell marker fibroblast activation protein correlates with the degree of fibrosis in hepatitis C virus infection

inferredcites →https://doi.org/10.1038/labinvest.2012.54openalex-snapshot

NK cells from HCV-infected patients effectively induce apoptosis of activated primary human hepatic stellate cells in a TRAIL-, FasL- and NKG2D-dependent manner

inferredcites →https://doi.org/10.1038/labinvest.2013.135openalex-snapshot

Cytoglobin is expressed in hepatic stellate cells, but not in myofibroblasts, in normal and fibrotic human liver

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Immortal Activated Human Hepatic Stellate Cells Generated by Ectopic Telomerase Expression

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Fate tracing reveals hepatic stellate cells as dominant contributors to liver fibrosis independent of its aetiology

inferredcites →https://doi.org/10.1038/nm.3282openalex-snapshot

Targeting of αv integrin identifies a core molecular pathway that regulates fibrosis in several organs

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Retinoic acid suppresses the response to platelet-derived growth factor in human hepatic Ito-cell-like myofibroblasts: a post-receptor mechanism independent of raf/fos/jun/egr activation

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Natural Killer Cells Ameliorate Liver Fibrosis by Killing Activated Stellate Cells in NKG2D-Dependent and Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand–Dependent Manners

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Gene Expression Profiles During Hepatic Stellate Cell Activation in Culture and In Vivo

inferredcites →https://doi.org/10.1053/j.gastro.2008.04.010openalex-snapshot

Platelet-Derived Growth Factor Signaling Through Ephrin-B2 Regulates Hepatic Vascular Structure and Function

inferredcites →https://doi.org/10.1053/jhep.2000.9322openalex-snapshot

Proteome analysis of rat hepatic stellate cells

inferredcites →https://doi.org/10.1053/jhep.2001.20793openalex-snapshot

Human and Rat Hepatic Stellate Cells Express Neurotrophins and Neurotrophin Receptors

inferredcites →https://doi.org/10.1053/jhep.2003.50005openalex-snapshot

Foxf1 +/− mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injury

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Replicative Senescence of Activated Human Hepatic Stellate Cells Is Accompanied by A Pronounced Inflammatory But Less Fibrogenic Phenotype

inferredcites →https://doi.org/10.1055/s-2001-17550openalex-snapshot

History, Heterogeneity, Developmental Biology, and Functions of Quiescent Hepatic Stellate Cells

inferredcites →https://doi.org/10.1073/pnas.1201840109openalex-snapshot

Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

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Fibrogenic cell reversion underlies fibrosis regression in liver

inferredcites →https://doi.org/10.1073/pnas.1522163112openalex-snapshot

BRD4 is a novel therapeutic target for liver fibrosis

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Biological Effects of C-type Natriuretic Peptide in Human Myofibroblastic Hepatic Stellate Cells

inferredcites →https://doi.org/10.1074/jbc.m102630200openalex-snapshot

Characterization of a Stellate Cell Activation-associated Protein (STAP) with Peroxidase Activity Found in Rat Hepatic Stellate Cells

inferredcites →https://doi.org/10.1074/jbc.m310284200openalex-snapshot

Peroxisome Proliferator-activated Receptor γ Induces a Phenotypic Switch from Activated to Quiescent Hepatic Stellate Cells

inferredcites →https://doi.org/10.1083/jcb.72.2.441openalex-snapshot

Distribution of organelles and membranes between hepatocytes and nonhepatocytes in the rat liver parenchyma. A stereological study.

inferredcites →https://doi.org/10.1083/jcb.98.5.1696openalex-snapshot

Immunocytochemical studies on the localization of plasma and of cellular retinol-binding proteins and of transthyretin (prealbumin) in rat liver and kidney.

inferredcites →https://doi.org/10.1093/hmg/ddu121openalex-snapshot

PNPLA3 has retinyl-palmitate lipase activity in human hepatic stellate cells

inferredcites →https://doi.org/10.1097/01.tp.0000064621.50907.a6openalex-snapshot

Establishment of immortalized human hepatic stellate scavenger cells to develop bioartificial livers1

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Mechanism of impairment on liver regeneration in elderly patients: Role of hepatic stellate cell function

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Hepatic stellate cells and the reversal of fibrosis

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What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis

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Liver fibrosis: searching for cell model answers

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Lecithin: retinol acyltransferase protein is distributed in both hepatic stellate cells and endothelial cells of normal rodent and human liver

inferredcites →https://doi.org/10.1111/j.1478-3231.2010.02342.xopenalex-snapshot

Fibrogenic cell phenotype modifications during remodelling of normal and pathological human liver in cultured slices

inferredcites →https://doi.org/10.1111/j.1582-4934.2007.00060.xopenalex-snapshot

Immortal hepatic stellate cell lines: useful tools to study hepatic stellate cell biology and function?

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The myofibroblast: phenotypic characterization as a prerequisite to understanding its functions in translational medicine

inferredcites →https://doi.org/10.1111/j.1600-0676.1991.tb00499.xopenalex-snapshot

Appearance of α‐smooth‐muscle‐actin‐positive cells in hepatic fibrosis

inferredcites →https://doi.org/10.1111/j.1872-034x.2011.00893.xopenalex-snapshot

Platelet‐derived adenosine 5′‐triphosphate suppresses activation of human hepatic stellate cell: In vitro study

inferredcites →https://doi.org/10.1111/liv.12255openalex-snapshot

Hepatic stellate cells that coexpress LRAT and CRBP ‐1 partially contribute to portal fibrogenesis in patients with human viral hepatitis

inferredcites →https://doi.org/10.1136/gut.2003.026658openalex-snapshot

Hepatic fibrogenesis requires sympathetic neurotransmitters

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Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis

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CD248/endosialin critically regulates hepatic stellate cell proliferation during chronic liver injury via a PDGF-regulated mechanism

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Epigenetics in liver disease: from biology to therapeutics

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Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver

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Differential Lipotoxic Effects of Palmitate and Oleate in Activated Human Hepatic Stellate Cells and Epithelial Hepatoma Cells

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The Rate of Synthesis of Glycosaminoglycans and Collagen by Fibroblasts Cultured from Adult Human Liver Biopsies

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Fat-storing cells as liver-specific pericytes. Spatial dynamics of agonist-stimulated intracellular calcium transients.

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Cultured human liver fat-storing cells produce monocyte chemotactic protein-1. Regulation by proinflammatory cytokines.

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Induction of beta-platelet-derived growth factor receptor in rat hepatic lipocytes during cellular activation in vivo and in culture.

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Liver fibrosis

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Liver fibrosis

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In vitro reversion of activated primary human hepatic stellate cells

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Cytoglobin expression in the hepatic stellate cell line HSC-T6 is regulated by extracellular matrix proteins dependent on FAK-signalling

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PDGF and signal transduction in hepatic stellate cells

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Mechanisms of Fibrogenesis

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Establishment of an Immortalized Human Hepatic Stellate Cell Line to Develop Antifibrotic Therapies

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Protocol for Isolation of Primary Human Hepatocytes and Corresponding Major Populations of Non-parenchymal Liver Cells

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Hepatic Stellate Cells Function as Regulatory Bystanders

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Establishment and Characterization of an Immortalized Human Hepatic Stellate Cell Line for Applications in Co-Culturing with Immortalized Human Hepatocytes

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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inferred← citeshttps://doi.org/10.1016/j.jnutbio.2019.06.001openalex-snapshot

Astaxanthin attenuates the increase in mitochondrial respiration during the activation of hepatic stellate cells

inferred← citeshttps://doi.org/10.1016/j.jnutbio.2024.109749openalex-snapshot

Coconut oil affects aging-related changes in Mongolian gerbil liver morphophysiology

inferred← citeshttps://doi.org/10.1016/j.stemcr.2022.09.010openalex-snapshot

Generation of functionally competent hepatic stellate cells from human stem cells to model liver fibrosis in vitro

inferred← citeshttps://doi.org/10.1016/j.tem.2022.07.001openalex-snapshot

Immune–metabolic interactions in homeostasis and the progression to NASH

inferred← citeshttps://doi.org/10.1016/j.tiv.2019.06.002openalex-snapshot

Bile salts regulate CYP7A1 expression and elicit a fibrotic response and abnormal lipid production in 3D liver microtissues

inferred← citeshttps://doi.org/10.1021/acs.jproteome.2c00190openalex-snapshot

A Cytological Atlas of the Human Liver Proteome from PROTEOMESKY-LIVERHu 2.0, a Publicly Available Database

inferred← citeshttps://doi.org/10.1038/s41419-023-06351-5openalex-snapshot

The chromatin remodeling protein BRG1 regulates HSC-myofibroblast differentiation and liver fibrosis

inferred← citeshttps://doi.org/10.1038/s41419-024-06726-2openalex-snapshot

Role of T cells in liver metastasis

inferred← citeshttps://doi.org/10.1038/s41467-023-35861-1openalex-snapshot

Western diet contributes to the pathogenesis of non-alcoholic steatohepatitis in male mice via remodeling gut microbiota and increasing production of 2-oleoylglycerol

inferred← citeshttps://doi.org/10.1038/s41467-024-47949-3openalex-snapshot

Macrophage-fibroblast JAK/STAT dependent crosstalk promotes liver metastatic outgrowth in pancreatic cancer

inferred← citeshttps://doi.org/10.1038/s41556-025-01638-5openalex-snapshot

Effects of embryonic origin, tissue cues and pathological signals on fibroblast diversity in humans

inferred← citeshttps://doi.org/10.1038/s41598-021-91187-2openalex-snapshot

Pirfenidone modifies hepatic miRNAs expression in a model of MAFLD/NASH

inferred← citeshttps://doi.org/10.1039/d2lc00940dopenalex-snapshot

Opportunities and considerations for studying liver disease with microphysiological systems on a chip

inferred← citeshttps://doi.org/10.1042/cs20230533openalex-snapshot

Therapeutic implication of human placental extract to prevent liver cirrhosis in rats with metabolic dysfunction-associated steatohepatitis

inferred← citeshttps://doi.org/10.1053/j.gastro.2020.12.015openalex-snapshot

Hepatic Stellate Cells in Hepatocellular Carcinoma Promote Tumor Growth Via Growth Differentiation Factor 15 Production

inferred← citeshttps://doi.org/10.1063/5.0331517openalex-snapshot

Liver lobule models incorporating the space of Disse and their applications

inferred← citeshttps://doi.org/10.1080/15548627.2018.1503146openalex-snapshot

Activation of ferritinophagy is required for the RNA-binding protein ELAVL1/HuR to regulate ferroptosis in hepatic stellate cells

inferred← citeshttps://doi.org/10.1080/15548627.2019.1687985openalex-snapshot

RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells

inferred← citeshttps://doi.org/10.1089/ten.teb.2020.0229openalex-snapshot

Implementation of Pericytes in Vascular Regeneration Strategies

inferred← citeshttps://doi.org/10.1089/ten.tec.2018.0134openalex-snapshot

Three-Dimensional Spheroid Primary Human Hepatocytes in Monoculture and Coculture with Nonparenchymal Cells

inferred← citeshttps://doi.org/10.1093/bbb/zbab001openalex-snapshot

Study on the effect of Mongolian medicine Qiwei Qinggan Powder on hepatic fibrosis through JAK2/STAT3 pathway

inferred← citeshttps://doi.org/10.1093/biomethods/bpaf023openalex-snapshot

Optimized immunofluorescence for liver structure analysis: Enhancing 3D resolution and minimizing tissue autofluorescence

inferred← citeshttps://doi.org/10.1093/jpp/rgaa042openalex-snapshot

Paeoniflorin modulates oxidative stress, inflammation and hepatic stellate cells activation to alleviate CCl4-induced hepatic fibrosis by upregulation of heme oxygenase-1 in mice

inferred← citeshttps://doi.org/10.1096/fj.202600972ropenalex-snapshot

C–C Motif Chemokine Ligand 7 Promotes HSC ‐Myofibroblast Transition and Liver Fibrosis by Enabling SREBP2 ‐Dependent Cholesterologenesis

inferred← citeshttps://doi.org/10.1097/cm9.0000000000004155openalex-snapshot

Multiomics contributes to the discovery of common factors in alcohol- and hepatitis B virus-related liver fibrosis

inferred← citeshttps://doi.org/10.1101/2023.03.03.531042openalex-snapshot

Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling

inferred← citeshttps://doi.org/10.1111/febs.70073openalex-snapshot

Tudor staphylococcal nuclease (Tudor‐ SN ) regulates activation of quiescent hepatic stellate cells

inferred← citeshttps://doi.org/10.1111/hepr.13275openalex-snapshot

Stevia prevents experimental cirrhosis by reducing hepatic myofibroblasts and modulating molecular profibrotic pathways

inferred← citeshttps://doi.org/10.1111/hepr.13317openalex-snapshot

Vitamin A‐coupled liposomal Rho‐kinase inhibitor ameliorates liver fibrosis without systemic adverse effects

inferred← citeshttps://doi.org/10.1111/jgh.16221openalex-snapshot

Multi‐omics profiling of primary hepatic stellate cells from advanced liver fibrosis patients reveals distinctive molecular signatures

inferred← citeshttps://doi.org/10.1111/jgh.16538openalex-snapshot

Novel protein C6ORF120 promotes liver fibrosis by activating hepatic stellate cells through the PI3K/Akt/mTOR pathway

inferred← citeshttps://doi.org/10.1111/liv.14945openalex-snapshot

Inhibiting xCT/SLC7A11 induces ferroptosis of myofibroblastic hepatic stellate cells but exacerbates chronic liver injury

inferred← citeshttps://doi.org/10.1126/scisignal.adf6696openalex-snapshot

Hepatic stellate cells maintain liver homeostasis through paracrine neurotrophin-3 signaling that induces hepatocyte proliferation

inferred← citeshttps://doi.org/10.1134/s0022093024050090openalex-snapshot

Astrocyte Marker GFAP in Gliocytes of Peripheral Nervous System

inferred← citeshttps://doi.org/10.1136/jitc-2026-015099openalex-snapshot

N-glycans in non-malignant tumor microenvironment cells dampen CAR-T cell function in solid tumors

inferred← citeshttps://doi.org/10.1152/ajpcell.00803.2025openalex-snapshot

A hepatocyte membrane-based culture system recapitulating the physiological microenvironment of hepatic stellate cells

inferred← citeshttps://doi.org/10.1177/1535370220949148openalex-snapshot

Endothelin-1 in portal hypertension: The intricate role of hepatic stellate cells

inferred← citeshttps://doi.org/10.1177/15353702221142604openalex-snapshot

Role of follistatin-like protein 1 in liver diseases

inferred← citeshttps://doi.org/10.1177/1934578x231194127openalex-snapshot

Network Pharmacology, Molecular Docking, Molecular Dynamics Simulation, and in vitro Experiments to Explore the Mechanism of Asiatic Acid Inhibiting Acetaldehyde-Induced Activation of Hepatic Stellate Cells

inferred← citeshttps://doi.org/10.1186/s12951-022-01636-xopenalex-snapshot

Huc-MSC-derived exosomes modified with the targeting peptide of aHSCs for liver fibrosis therapy

inferred← citeshttps://doi.org/10.1248/bpb.b24-00035openalex-snapshot

Group IVA Phospholipase A2 in Collagen-Producing Cells Promotes High-Fat Diet-Induced Infiltration of Inflammatory Cells into the Liver by Upregulating the Expression of MCP-1

inferred← citeshttps://doi.org/10.12750/jarb.35.2.113openalex-snapshot

The role of hepatic stellate cells in fibrotic liver diseases

inferred← citeshttps://doi.org/10.1371/journal.pntd.0009472openalex-snapshot

The role of let-7b in the inhibition of hepatic stellate cell activation by rSjP40

inferred← citeshttps://doi.org/10.1371/journal.pone.0234038openalex-snapshot

Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis

inferred← citeshttps://doi.org/10.1371/journal.pone.0260721openalex-snapshot

PNPLA3 downregulation exacerbates the fibrotic response in human hepatic stellate cells

inferred← citeshttps://doi.org/10.1667/rade-23-00127.1openalex-snapshot

Hepatic Stellate Cell-mediated Increase in CCL5 Chemokine Expression after X-ray Irradiation Determined In Vitro and In Vivo

inferred← citeshttps://doi.org/10.1667/rr15550.1openalex-snapshot

Circular RNA TUBD1 Acts as the miR-146a-5p Sponge to Affect the Viability and Pro-Inflammatory Cytokine Production of LX-2 Cells through the TLR4 Pathway

inferred← citeshttps://doi.org/10.21037/atm-21-4215openalex-snapshot

Profiles of messenger RNAs and MicroRNAs in hypoxia-induced hepatic stellate cells

inferred← citeshttps://doi.org/10.21203/rs.3.rs-183605/v1openalex-snapshot

A Robust and Simple Patient-derived Multicellular Spheroid Model Enables Liver Cancer Precision Drug Screening

inferred← citeshttps://doi.org/10.21203/rs.3.rs-29050/v1openalex-snapshot

Study on the effect Mongolian Medicine Qiwei Qinggan Powder on Hepatic Fibrosis through JAK2/STAT3 Pathway

inferred← citeshttps://doi.org/10.2147/dddt.s511372openalex-snapshot

Curcumin Analog J7 Attenuates Liver Fibrosis and Metabolic Dysregulation in a Rat Model of Type 2 Diabetes via Modulation of TGF-β/Smad and NF-κB/BCL-2/BAX Pathways

inferred← citeshttps://doi.org/10.2174/1389450124666230330135834openalex-snapshot

Targeting Hepatic Stellate Cell Death to Reverse Hepatic Fibrosis

inferred← citeshttps://doi.org/10.2174/1874467213666200224102820openalex-snapshot

Hepatic Stellate Cell: A Potential Target for Hepatocellular Carcinoma

inferred← citeshttps://doi.org/10.2217/rme-2020-0093openalex-snapshot

Phenotypic Assessment of Liver-Derived Cell Cultures during in vitro Expansion

inferred← citeshttps://doi.org/10.31083/j.fbl2809205openalex-snapshot

Zbtb14 Promotes Non-Alcoholic Fatty Liver Disease-Associated Fibrosis in Gerbils via the β-Catenin Pathway

inferred← citeshttps://doi.org/10.31857/s0869813924090015openalex-snapshot

Astrocyte marker GFAP in gliocytes of the peripheral nervous system

inferred← citeshttps://doi.org/10.33549/physiolres.934755openalex-snapshot

Hepatic Stellate Cell: A Double-Edged Sword in the Liver.

inferred← citeshttps://doi.org/10.33590/emj/10310892openalex-snapshot

A Review of Liver Fibrosis and Emerging Therapies

inferred← citeshttps://doi.org/10.33612/diss.128130988openalex-snapshot

Novel molecular targets in hepatic stellate cells for the treatment of liver fibrosis

inferred← citeshttps://doi.org/10.33612/diss.146692010openalex-snapshot

Targeting hepatic stellate cells to prevent or reverse liver fibrosis

inferred← citeshttps://doi.org/10.3389/fgene.2021.657330openalex-snapshot

Transcriptional Profiling of Porcine HCC Xenografts Provides Insights Into Tumor Cell Microenvironment Signaling

inferred← citeshttps://doi.org/10.3389/fimmu.2018.02921openalex-snapshot

TLR3 Activation of Hepatic Stellate Cell Line Suppresses HBV Replication in HepG2 Cells

inferred← citeshttps://doi.org/10.3389/fmed.2021.604894openalex-snapshot

Novel Immune Subsets and Related Cytokines: Emerging Players in the Progression of Liver Fibrosis

inferred← citeshttps://doi.org/10.3389/fmed.2021.610189openalex-snapshot

The Charming World of the Extracellular Matrix: A Dynamic and Protective Network of the Intestinal Wall

inferred← citeshttps://doi.org/10.3389/fmicb.2022.927245openalex-snapshot

Akkermansia muciniphila Enhances Egg Quality and the Lipid Profile of Egg Yolk by Improving Lipid Metabolism

inferred← citeshttps://doi.org/10.3389/fmolb.2023.1221669openalex-snapshot

Cellular heterogeneity and plasticity during NAFLD progression

inferred← citeshttps://doi.org/10.3389/fphar.2018.01018openalex-snapshot

Magnesium Isoglycyrrhizinate Ameliorates Fibrosis and Disrupts TGF-β-Mediated SMAD Pathway in Activated Hepatic Stellate Cell Line LX2

inferred← citeshttps://doi.org/10.3389/fphar.2019.00431openalex-snapshot

Interaction Mechanisms Between the NOX4/ROS and RhoA/ROCK1 Signaling Pathways as New Anti- fibrosis Targets of Ursolic Acid in Hepatic Stellate Cells

inferred← citeshttps://doi.org/10.3389/fphar.2020.00165openalex-snapshot

Activation of BK Channels Prevents Hepatic Stellate Cell Activation and Liver Fibrosis Through the Suppression of TGFβ1/SMAD3 and JAK/STAT3 Profibrotic Signaling Pathways

inferred← citeshttps://doi.org/10.3389/fphar.2020.574441openalex-snapshot

L-Carnitine Mitigates Oxidative Stress and Disorganization of Cytoskeleton Intermediate Filaments in Cisplatin-Induced Hepato-Renal Toxicity in Rats

inferred← citeshttps://doi.org/10.3389/fphar.2021.655531openalex-snapshot

The Combination of Schisandrol B and Wedelolactone Synergistically Reverses Hepatic Fibrosis Via Modulating Multiple Signaling Pathways in Mice

inferred← citeshttps://doi.org/10.3389/fphar.2025.1734449openalex-snapshot

From mechanisms to anti-fibrotic drugs in hepatic stellate cell research: a global bibliometric analysis with patent and clinical perspectives (2000–2025)

inferred← citeshttps://doi.org/10.3389/fvets.2022.1014648openalex-snapshot

Liver tissue remodeling following ablation with irreversible electroporation in a porcine model

inferred← citeshttps://doi.org/10.3390/biomedicines10123234openalex-snapshot

Eph/Ephrin Promotes the Adhesion of Liver Tissue-Resident Macrophages to a Mimicked Surface of Liver Sinusoidal Endothelial Cells

inferred← citeshttps://doi.org/10.3390/cancers11081043openalex-snapshot

Synergic Interactions Between Hepatic Stellate Cells and Uveal Melanoma in Metastatic Growth

inferred← citeshttps://doi.org/10.3390/cells11091379openalex-snapshot

Optimized Isolation and Characterization of C57BL/6 Mouse Hepatic Stellate Cells

inferred← citeshttps://doi.org/10.3390/cells13090765openalex-snapshot

Novel Inositol 1,4,5-Trisphosphate Receptor Inhibitor Antagonizes Hepatic Stellate Cell Activation: A Potential Drug to Treat Liver Fibrosis

inferred← citeshttps://doi.org/10.3390/cells13191643openalex-snapshot

Liver Fibrosis Is Enhanced by a Higher Egg Burden in Younger Mice Infected with S. mansoni

inferred← citeshttps://doi.org/10.3390/cells8101127openalex-snapshot

Mesenchymal Stem Cells in the Adult Human Liver: Hype or Hope?

inferred← citeshttps://doi.org/10.3390/cells9112456openalex-snapshot

Simultaneous Induction of Glycolysis and Oxidative Phosphorylation during Activation of Hepatic Stellate Cells Reveals Novel Mitochondrial Targets to Treat Liver Fibrosis

inferred← citeshttps://doi.org/10.3390/ijms22095038openalex-snapshot

In Vitro Liver Toxicity Testing of Chemicals: A Pragmatic Approach

inferred← citeshttps://doi.org/10.3390/ijms221910439openalex-snapshot

The Multiple Faces of Integrin–ECM Interactions in Inflammatory Bowel Disease

inferred← citeshttps://doi.org/10.3390/ijms222111629openalex-snapshot

Pathophysiological Molecular Mechanisms of Obesity: A Link between MAFLD and NASH with Cardiovascular Diseases

inferred← citeshttps://doi.org/10.3390/ijms26062658openalex-snapshot

Decoding Liver Fibrosis: How Omics Technologies and Innovative Modeling Can Guide Precision Medicine

inferred← citeshttps://doi.org/10.3390/jcm9113510openalex-snapshot

Accuracy of Fibrosis-4 Index in Identification of Patients with Cirrhosis Who Could Potentially Avoid Variceal Screening Endoscopy

inferred← citeshttps://doi.org/10.3390/medicina55020056openalex-snapshot

Recently Discovered Interstitial Cell Population of Telocytes: Distinguishing Facts from Fiction Regarding Their Role in the Pathogenesis of Diverse Diseases Called “Telocytopathies”

inferred← citeshttps://doi.org/10.3390/ph16010114openalex-snapshot

Oxy210, a Semi-Synthetic Oxysterol, Inhibits Profibrotic Signaling in Cellular Models of Lung and Kidney Fibrosis

inferred← citeshttps://doi.org/10.3724/abbs.2024191openalex-snapshot

Tim-1-mediated extracellular matrix promotes the development of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.3748/wjg.v28.i46.6433openalex-snapshot

Recent progress in molecular mechanisms of postoperative recurrence and metastasis of hepatocellular carcinoma

inferred← citeshttps://doi.org/10.4081/ejh.2021.3337openalex-snapshot

Autofluorescence in freshly isolated adult human liver sinusoidal cells

inferred← citeshttps://doi.org/10.47162/rjme.61.3.01openalex-snapshot

Hepatic stellate cells – from past till present: morphology, human markers, human cell lines, behavior in normal and liver pathology

inferred← citeshttps://doi.org/10.7150/ijbs.97304openalex-snapshot

Tenovin-1, a Selective SIRT1/2 Inhibitor, Attenuates High-fat Diet-induced Hepatic Fibrosis via Inhibition of HSC Activation in ZDF Rats

inferred← citeshttps://doi.org/10.7150/thno.77256openalex-snapshot

Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases

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