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Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis

https://doi.org/10.1073/pnas.1201840109
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/gene.20004openalex-snapshot
Cre recombinase‐mediated gene targeting of mesenchymal cells
inferredcites →https://doi.org/10.1002/hep.22193openalex-snapshot
The role of matrix stiffness in regulating cell behavior†
inferredcites →https://doi.org/10.1002/hep.22721openalex-snapshot
Mesenchymal origin of hepatic stellate cells, submesothelial cells, and perivascular mesenchymal cells during mouse liver development†
inferredcites →https://doi.org/10.1002/micr.20365openalex-snapshot
Cotransplanted hepatic stellate cells enhance vascularization of islet allografts
inferredcites →https://doi.org/10.1007/978-1-59745-242-7_3openalex-snapshot
Intragastric Ethanol Infusion Model in Rodents
inferredcites →https://doi.org/10.1016/j.cell.2008.06.049openalex-snapshot
Senescence of Activated Stellate Cells Limits Liver Fibrosis
inferredcites →https://doi.org/10.1016/j.immuni.2006.11.011openalex-snapshot
Ito Cells Are Liver-Resident Antigen-Presenting Cells for Activating T Cell Responses
inferredcites →https://doi.org/10.1016/s0168-8278(01)00053-8openalex-snapshot
A non-toxic heat shock protein 70 inducer, geranylgeranylacetone, suppresses apoptosis of cultured rat hepatocytes caused by hydrogen peroxide and ethanol
inferredcites →https://doi.org/10.1038/nm1663openalex-snapshot
TLR4 enhances TGF-β signaling and hepatic fibrosis
inferredcites →https://doi.org/10.1046/j.1365-2141.1998.00980.xopenalex-snapshot
Enhanced human cell engraftment in mice deficient in RAG2 and the common cytokine receptor γ chain
inferredcites →https://doi.org/10.1053/gast.2001.27188openalex-snapshot
Gliotoxin stimulates the apoptosis of human and rat hepatic stellate cells and enhances the resolution of liver fibrosis in rats
inferredcites →https://doi.org/10.1053/jhep.2003.50005openalex-snapshot
Foxf1 +/− mice exhibit defective stellate cell activation and abnormal liver regeneration following CCl4 injury
inferredcites →https://doi.org/10.1053/jhep.2003.50067openalex-snapshot
DNase I-hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells
inferredcites →https://doi.org/10.1073/pnas.82.24.8681openalex-snapshot
Hepatic lipocytes: the principal collagen-producing cells of normal rat liver.
inferredcites →https://doi.org/10.1074/jbc.m209175200openalex-snapshot
5′ Stem-Loop of Collagen α1(I) mRNA Inhibits Translationin Vitro but Is Required for Triple Helical Collagen Synthesis in Vivo
inferredcites →https://doi.org/10.1074/jbc.m410078200openalex-snapshot
Adipogenic Transcriptional Regulation of Hepatic Stellate Cells
inferredcites →https://doi.org/10.1084/jem.20040104openalex-snapshot
Early Growth Response Gene 1–mediated Apoptosis Is Essential for Transforming Growth Factor β1–induced Pulmonary Fibrosis
inferredcites →https://doi.org/10.1096/fj.06-7717comopenalex-snapshot
The endocannabinoid 2‐arachidonoyl glycerol induces death of hepatic stellate cells via mitochondrial reactive oxygen species
inferredcites →https://doi.org/10.1097/01.alc.0000189279.92602.f0openalex-snapshot
Adipogenic Phenotype of Hepatic Stellate Cells
inferredcites →https://doi.org/10.1111/j.1749-6632.2005.tb00012.xopenalex-snapshot
Antiapoptotic and Anti-inflammatory Mechanisms of Heat-Shock Protein Protection
inferredcites →https://doi.org/10.1128/mcb.20.18.6826-6836.2000openalex-snapshot
Hsp72-Mediated Suppression of c-Jun N-Terminal Kinase Is Implicated in Development of Tolerance to Caspase-Independent Cell Death
inferredcites →https://doi.org/10.1172/jci1018openalex-snapshot
Mechanisms of spontaneous resolution of rat liver fibrosis. Hepatic stellate cell apoptosis and reduced hepatic expression of metalloproteinase inhibitors.
inferredcites →https://doi.org/10.1172/jci118304openalex-snapshot
Activation of hepatic stellate cells by TGF alpha and collagen type I is mediated by oxidative stress through c-myb expression.
inferredcites →https://doi.org/10.1172/jci200524282c1openalex-snapshot
Liver fibrosis
inferredcites →https://doi.org/10.1172/jci24282openalex-snapshot
Liver fibrosis
inferredcites →https://doi.org/10.1371/journal.pone.0006721openalex-snapshot
Restoration of Podocyte Structure and Improvement of Chronic Renal Disease in Transgenic Mice Overexpressing Renin
inferredcites →https://doi.org/10.1385/1-59259-773-4:219openalex-snapshot
Multiparameter Flow Cytometry of Fluorescent Protein Reporters

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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CD73 Aggravates Alcohol-Related Liver Fibrosis by Promoting Autophagy Mediated Activation of Hepatic Stellate Cells Through Ampk/Akt/Mtor Signaling Pathway
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Hedgehog signaling in the liver
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Hepatic Fibrogenesis
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Hepatic Fibrosis
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Stellate Cells and Fibrosis
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The Rule‐Based Model Approach:A Kappa Model for Hepatic Stellate Cells Activation by TGFB1
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The Material World of 3D‐Bioprinted and Microfluidic‐Chip Models of Human Liver Fibrosis
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Protozoan‐Derived Cytokine‐Transgenic Macrophages Reverse Hepatic Fibrosis
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Targeting Fibrosis: From Molecular Mechanisms to Advanced Therapies
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In vitro modeling of liver fibrosis with 3D co‐culture system using a novel human hepatic stellate cell line
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Carboxymethyl chitosan prolongs adenovirus‐mediated expression of IL ‐10 and ameliorates hepatic fibrosis in a mouse model
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Molecular interplays in hepatic stellate cells: apoptosis, senescence, and phenotype reversion as cellular connections that modulate liver fibrosis
inferred← citeshttps://doi.org/10.1002/ccs3.12015openalex-snapshot
Survivin inhibition ameliorates liver fibrosis by inducing hepatic stellate cell senescence and depleting hepatic macrophage population
inferred← citeshttps://doi.org/10.1002/cpdd.336openalex-snapshot
Assessment of Hepatic Impairment and Implications for Pharmacokinetics of Substance Use Treatment
inferred← citeshttps://doi.org/10.1002/cphy.c120035openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/hep.26230openalex-snapshot
Hedgehog pathway and pediatric nonalcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1002/hep.26429openalex-snapshot
Hepatic macrophages but not dendritic cells contribute to liver fibrosis by promoting the survival of activated hepatic stellate cells in mice
inferred← citeshttps://doi.org/10.1002/hep.26627openalex-snapshot
Relaxin modulates human and rat hepatic myofibroblast function and ameliorates portal hypertension in vivo
inferred← citeshttps://doi.org/10.1002/hep.26637openalex-snapshot
Fra, Fra Away: The complex role of activator protein 1 in liver injury
inferred← citeshttps://doi.org/10.1002/hep.27035openalex-snapshot
Mesodermal Mesenchymal Cells Give Rise to Myofibroblasts, but Not Epithelial Cells, in Mouse Liver Injury
inferred← citeshttps://doi.org/10.1002/hep.27376openalex-snapshot
Liver sinusoidal endothelial cells in hepatic fibrosis
inferred← citeshttps://doi.org/10.1002/hep.27383openalex-snapshot
Osteopontin deficiency does not prevent but promotes alcoholic neutrophilic hepatitis in mice
inferred← citeshttps://doi.org/10.1002/hep.27606openalex-snapshot
Cre‐ativity in the liver: Transgenic approaches to targeting hepatic nonparenchymal cells
inferred← citeshttps://doi.org/10.1002/hep.27659openalex-snapshot
Determining the fate of hepatic cells by lineage tracing: Facts and pitfalls
inferred← citeshttps://doi.org/10.1002/hep.27720openalex-snapshot
Strategies and endpoints of antifibrotic drug trials: Summary and recommendations from the AASLD Emerging Trends Conference, Chicago, June 2014
inferred← citeshttps://doi.org/10.1002/hep.28933openalex-snapshot
Deregulated neddylation in liver fibrosis
inferred← citeshttps://doi.org/10.1002/hep.30965openalex-snapshot
A Deactivation Factor of Fibrogenic Hepatic Stellate Cells Induces Regression of Liver Fibrosis in Mice
inferred← citeshttps://doi.org/10.1002/hep.31151openalex-snapshot
Taming the Savage Breast From Within: Transcription Factor 21, a Regulator of Stellate Cell Deactivation
inferred← citeshttps://doi.org/10.1002/hep.31743openalex-snapshot
Heterogeneity of HSCs in a Mouse Model of NASH
inferred← citeshttps://doi.org/10.1002/hep.31754openalex-snapshot
Myofibroblast‐Specific Msi2 Knockout Inhibits HCC Progression in a Mouse Model
inferred← citeshttps://doi.org/10.1002/hep.32776openalex-snapshot
Interleukin‐18 signaling promotes activation of hepatic stellate cells in mouse liver fibrosis
inferred← citeshttps://doi.org/10.1002/hep4.1331openalex-snapshot
Role of the Gut–Liver Axis in Liver Inflammation, Fibrosis, and Cancer: A Special Focus on the Gut Microbiota Relationship
inferred← citeshttps://doi.org/10.1002/hep4.1628openalex-snapshot
Hepatic Stellate Cell Regulation of Liver Regeneration and Repair
inferred← citeshttps://doi.org/10.1002/hep4.2058openalex-snapshot
Loss of heat shock factor 1 promotes hepatic stellate cell activation and drives liver fibrosis
inferred← citeshttps://doi.org/10.1002/iub.1742openalex-snapshot
Effect of histone deacetylase inhibitor on epithelial‐mesenchymal transition of liver fibrosis
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2013.tb00529.xopenalex-snapshot
Hepatic Stellate Cells and Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/jbm.a.35456openalex-snapshot
Varying RGD concentration and cell phenotype alters the expression of extracellular matrix genes in vocal fold fibroblasts
inferred← citeshttps://doi.org/10.1002/jcp.30582openalex-snapshot
Hepatic stellate cells in the injured liver: Perspectives beyond hepatic fibrosis
inferred← citeshttps://doi.org/10.1002/jcp.30877openalex-snapshot
Differential recruitment of monocyte‐derived macrophages in control and stellate cell‐depleted mice during recurrent carbon tetrachloride‐induced acute liver injury
inferred← citeshttps://doi.org/10.1002/jhbp.245openalex-snapshot
Recent advancement of molecular mechanisms of liver fibrosis
inferred← citeshttps://doi.org/10.1002/lci2.70015openalex-snapshot
Phytotherapy for Liver Fibrosis: Insights From the Biology of Hepatic Stellate Cells—A Narrative Review
inferred← citeshttps://doi.org/10.1002/mnfr.201400649openalex-snapshot
Inhibitory effect of dietary capsaicin on liver fibrosis in mice
inferred← citeshttps://doi.org/10.1002/path.4373openalex-snapshot
MicroRNA ‐101 suppresses liver fibrosis by targeting the TGF β signalling pathway
inferred← citeshttps://doi.org/10.1002/path.4707openalex-snapshot
Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation
inferred← citeshttps://doi.org/10.1002/pmic.201300539openalex-snapshot
SILAC‐based quantitative proteomic analysis of secretome between activated and reverted hepatic stellate cells
inferred← citeshttps://doi.org/10.1002/ptr.6784openalex-snapshot
A survey of herbal medicines as tumor microenvironment‐modulating agents
inferred← citeshttps://doi.org/10.1002/ptr.8193openalex-snapshot
Plant‐derived flavonoids are a potential source of drugs for the treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1002/stem.2210openalex-snapshot
Molecular and Cellular Functions Distinguish Superior Therapeutic Efficiency of Bone Marrow CD45 Cells Over Mesenchymal Stem Cells in Liver Cirrhosis
inferred← citeshttps://doi.org/10.1002/stem.3449openalex-snapshot
Human Induced Pluripotent Stem Cell-Derived Macrophages Ameliorate Liver Fibrosis
inferred← citeshttps://doi.org/10.1002/term.2503openalex-snapshot
Hepatic perivascular mesenchymal stem cells with myogenic properties
inferred← citeshttps://doi.org/10.1002/wsbm.1499openalex-snapshot
Liver fibrosis: Pathophysiology and clinical implications
inferred← citeshttps://doi.org/10.1007/978-1-0716-1382-5_12openalex-snapshot
Why Stress Matters: An Introduction
inferred← citeshttps://doi.org/10.1007/978-1-0716-1382-5_2openalex-snapshot
Myofibroblast Functions in Tissue Repair and Fibrosis: An Introduction
inferred← citeshttps://doi.org/10.1007/978-1-0716-1382-5_20openalex-snapshot
Animal and Human Models of Tissue Repair and Fibrosis: An Introduction
inferred← citeshttps://doi.org/10.1007/978-1-0716-3207-9_12openalex-snapshot
Hepatic Stellate Cell Depletion and Genetic Manipulation
inferred← citeshttps://doi.org/10.1007/978-1-4939-6383-6_16openalex-snapshot
Discoidin Domain Receptors in Liver Fibrosis
inferred← citeshttps://doi.org/10.1007/978-3-030-55920-5_14openalex-snapshot
5-HT2B Receptors in Liver
inferred← citeshttps://doi.org/10.1007/978-3-319-02096-9_28openalex-snapshot
The Immunopathogenesis of Cirrhosis
inferred← citeshttps://doi.org/10.1007/978-3-319-13614-1_8openalex-snapshot
Reversal of Cirrhosis
inferred← citeshttps://doi.org/10.1007/978-3-319-17437-2_3openalex-snapshot
Mechanical and Matrix Regulation of Valvular Fibrosis
inferred← citeshttps://doi.org/10.1007/978-3-319-17437-2_5openalex-snapshot
The Stressful Life of Cardiac Myofibroblasts
inferred← citeshttps://doi.org/10.1007/978-3-319-20538-0_5openalex-snapshot
Animal Models of Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-64298-7_2openalex-snapshot
Chronic Liver Failure and Hepatic Cirrhosis
inferred← citeshttps://doi.org/10.1007/978-3-319-98143-7_15openalex-snapshot
Liver Fibrosis: Current Approaches and Future Directions for Diagnosis and Treatment
inferred← citeshttps://doi.org/10.1007/978-4-431-55651-0openalex-snapshot
Innovative Medicine: Basic Research and Development
inferred← citeshttps://doi.org/10.1007/978-4-431-55651-0_16openalex-snapshot
Clarity and Challenges in Tissue Fibrosis
inferred← citeshttps://doi.org/10.1007/978-4-431-56101-9_3openalex-snapshot
Hepatic Fibrosis in Hepatitis C
inferred← citeshttps://doi.org/10.1007/978-981-13-7979-6_15openalex-snapshot
Antifibrotic Therapy for Liver Cirrhosis
inferred← citeshttps://doi.org/10.1007/978-981-15-0391-7_2openalex-snapshot
Nanomedicine for Hepatic Fibrosis
inferred← citeshttps://doi.org/10.1007/s00018-015-2110-0openalex-snapshot
The myofibroblast, a key cell in normal and pathological tissue repair
inferred← citeshttps://doi.org/10.1007/s00018-019-03212-3openalex-snapshot
Molecular determinants of mesenchymal cell activation in fibroproliferative diseases
inferred← citeshttps://doi.org/10.1007/s00204-015-1543-4openalex-snapshot
Experimental models of liver fibrosis
inferred← citeshttps://doi.org/10.1007/s00204-017-2045-3openalex-snapshot
Adverse outcome pathways: opportunities, limitations and open questions
inferred← citeshttps://doi.org/10.1007/s00204-018-2254-4openalex-snapshot
Confounding influence of tamoxifen in mouse models of Cre recombinase-induced gene activity or modulation
inferred← citeshttps://doi.org/10.1007/s00408-025-00820-8openalex-snapshot
Pericytes in the Pulmonary Microenvironment: Guardians or Adversaries?
inferred← citeshttps://doi.org/10.1007/s00535-017-1404-4openalex-snapshot
Human hepatic stellate cell isolation and characterization
inferred← citeshttps://doi.org/10.1007/s10238-016-0438-xopenalex-snapshot
Senescence in hepatic stellate cells as a mechanism of liver fibrosis reversal: a putative synergy between retinoic acid and PPAR-gamma signalings
inferred← citeshttps://doi.org/10.1007/s10620-015-3976-2openalex-snapshot
Regulatory Effects and Mechanism of Adenovirus-Mediated PTEN Gene on Hepatic Stellate Cells
inferred← citeshttps://doi.org/10.1007/s10753-023-01831-4openalex-snapshot
Lymphocyte-Specific Protein Tyrosine Kinase Contributes to Spontaneous Regression of Liver Fibrosis may by Interacting with Suppressor of Cytokine Signaling 1
inferred← citeshttps://doi.org/10.1007/s11010-026-05504-2openalex-snapshot
Targeting EIF5A suppresses liver fibrosis through impairment of mitochondrial function in hepatic stellate cells
inferred← citeshttps://doi.org/10.1007/s11033-022-08210-6openalex-snapshot
Divergent effect of Birinapant, and BV6 SMAC mimetic on TNFα induced NF-κB signaling and cell viability in activated hepatic stellate cells
inferred← citeshttps://doi.org/10.1007/s11302-014-9410-yopenalex-snapshot
Role of adenosine A2B receptor signaling in contribution of cardiac mesenchymal stem-like cells to myocardial scar formation
inferred← citeshttps://doi.org/10.1007/s11596-024-2860-8openalex-snapshot
KLF4 Inhibits the Activation of Human Hepatic Stellate Cell In Vitro
inferred← citeshttps://doi.org/10.1007/s11926-020-00918-3openalex-snapshot
Current and Potential New Targets in Systemic Sclerosis Therapy: a New Hope
inferred← citeshttps://doi.org/10.1007/s12072-021-10135-4openalex-snapshot
Regression of portal hypertension: underlying mechanisms and therapeutic strategies
inferred← citeshttps://doi.org/10.1007/s12272-016-0809-6openalex-snapshot
Myofibroblasts and inflammatory cells as players of cardiac fibrosis
inferred← citeshttps://doi.org/10.1007/s13346-024-01551-8openalex-snapshot
Liver fibrosis pathologies and potentials of RNA based therapeutics modalities
inferred← citeshttps://doi.org/10.1007/s13577-022-00844-9openalex-snapshot
Induction of premature senescence and a less-fibrogenic phenotype by programmed cell death 4 knockdown in the human hepatic stellate cell line Lieming Xu-2
inferred← citeshttps://doi.org/10.1007/s40139-013-0018-7openalex-snapshot
Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts
inferred← citeshttps://doi.org/10.1007/s40139-013-0025-8openalex-snapshot
Myofibroblasts in Fibrotic Kidneys
inferred← citeshttps://doi.org/10.1007/s40139-014-0052-0openalex-snapshot
The Mechanisms of HSC Activation and Epigenetic Regulation of HSCs Phenotypes
inferred← citeshttps://doi.org/10.1007/s40139-014-0053-zopenalex-snapshot
New Approaches for Studying Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1007/s40139-014-0054-yopenalex-snapshot
Portal Fibroblasts in Biliary Fibrosis
inferred← citeshttps://doi.org/10.1007/s40139-014-0057-8openalex-snapshot
Strategies to Detect Hepatic Myofibroblasts in Liver Cirrhosis of Different Etiologies
inferred← citeshttps://doi.org/10.1007/s40139-014-0058-7openalex-snapshot
Extracellular Matrix Metabolism and Fibrotic Disease
inferred← citeshttps://doi.org/10.1007/s40139-016-0097-3openalex-snapshot
The Role of IL-17 Signaling in Regulation of the Liver–Brain Axis and Intestinal Permeability in Alcoholic Liver Disease
inferred← citeshttps://doi.org/10.1007/s40139-016-0103-9openalex-snapshot
Liver Fibrosis and Leptin
inferred← citeshttps://doi.org/10.1007/s40139-018-0168-8openalex-snapshot
Targeting Pericytes to Improve Wound Healing Outcomes
inferred← citeshttps://doi.org/10.1007/s40265-020-01458-xopenalex-snapshot
Strategies Targeting the Innate Immune Response for the Treatment of Hepatitis C Virus-Associated Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800102-8.00023-0openalex-snapshot
Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800134-9.00004-xopenalex-snapshot
Stellate Cells and Hepatic Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-800134-9.00006-3openalex-snapshot
Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition
inferred← citeshttps://doi.org/10.1016/b978-0-12-800134-9.00011-7openalex-snapshot
Hepatic Stellate Cells as Target for Reversal of Fibrosis/Cirrhosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.64267-8openalex-snapshot
Leading-Edge Approaches for In Vitro Hepatotoxicity Evaluation
inferred← citeshttps://doi.org/10.1016/b978-0-12-801238-3.64336-2openalex-snapshot
Mechanisms of Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-12-802761-5.00020-1openalex-snapshot
Molecular Basis of Liver Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-804274-8.00034-5openalex-snapshot
Portal Hypertension—Molecular Mechanisms
inferred← citeshttps://doi.org/10.1016/b978-0-12-809847-9.02001-8openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1016/b978-0-12-813257-9.00020-6openalex-snapshot
Molecular basis of liver disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-817068-7.02001-2openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1016/b978-0-323-34062-5.00007-8openalex-snapshot
Liver fibrogenesis
inferred← citeshttps://doi.org/10.1016/b978-0-323-37591-7.00005-7openalex-snapshot
The Liver's Response to Injury
inferred← citeshttps://doi.org/10.1016/b978-0-323-42873-6.00040-8openalex-snapshot
Regression of Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00240-0openalex-snapshot
Mechanisms of Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-323-99764-5.00010-xopenalex-snapshot
From inflammation to fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-323-99764-5.00014-7openalex-snapshot
Cells, cytokines, and factors involved in profibrogenic pathways
inferred← citeshttps://doi.org/10.1016/b978-0-443-15617-5.02001-1openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1016/b978-0-443-15717-2.00066-4openalex-snapshot
Stem Cells and Extracellular Vesicles for Prevention and Treatment of Liver Fibrosis
inferred← citeshttps://doi.org/10.1016/b978-0-443-34258-5.00004-9openalex-snapshot
Alcohol and liver physiology
inferred← citeshttps://doi.org/10.1016/b978-0-7020-6697-9.00001-7openalex-snapshot
Structure, Function, and Responses to Injury
inferred← citeshttps://doi.org/10.1016/b978-0-7020-8228-3.00001-6openalex-snapshot
Structure, Function and Responses to Injury
inferred← citeshttps://doi.org/10.1016/j.addr.2017.05.007openalex-snapshot
Hepatic stellate cells as key target in liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.addr.2017.05.018openalex-snapshot
Engineering in vitro models of hepatofibrogenesis
inferred← citeshttps://doi.org/10.1016/j.addr.2017.07.004openalex-snapshot
3D in vitro models of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2012.09.009openalex-snapshot
Transforming Growth Factor β-1 Stimulates Profibrotic Epithelial Signaling to Activate Pericyte-Myofibroblast Transition in Obstructive Kidney Fibrosis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2012.11.032openalex-snapshot
Absence of Nogo-B (Reticulon 4B) Facilitates Hepatic Stellate Cell Apoptosis and Diminishes Hepatic Fibrosis in Mice
inferred← citeshttps://doi.org/10.1016/j.ajpath.2014.02.003openalex-snapshot
Matrix Biology of Idiopathic Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2015.06.004openalex-snapshot
Hepatic Progenitor Cells in Action
inferred← citeshttps://doi.org/10.1016/j.ajpath.2015.07.022openalex-snapshot
Intratracheal Cell Transfer Demonstrates the Profibrotic Potential of Resident Fibroblasts in Pulmonary Fibrosis
inferred← citeshttps://doi.org/10.1016/j.ajpath.2016.01.018openalex-snapshot
Mechanisms of Lung Fibrosis Resolution
inferred← citeshttps://doi.org/10.1016/j.ajpath.2016.09.001openalex-snapshot
Hepatic Stellate Cell Selective Disruption of Dynamin-2 GTPase Increases Murine Fibrogenesis through Up-Regulation of Sphingosine-1 Phosphate–Induced Cell Migration
inferred← citeshttps://doi.org/10.1016/j.ajpath.2017.11.007openalex-snapshot
Fibroblasts Promote Inflammation and Pain via IL-1α Induction of the Monocyte Chemoattractant Chemokine (C-C Motif) Ligand 2
inferred← citeshttps://doi.org/10.1016/j.ajpath.2020.06.006openalex-snapshot
Hepatic Stellate Cell–Specific Platelet-Derived Growth Factor Receptor-α Loss Reduces Fibrosis and Promotes Repair after Hepatocellular Injury
inferred← citeshttps://doi.org/10.1016/j.ajpath.2025.02.003openalex-snapshot
Crosstalk between Hepatic Stellate Cells and Hepatic Macrophages in Metabolic Dysfunction–Associated Steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.amjms.2017.08.012openalex-snapshot
Iron Enhances Hepatic Fibrogenesis and Activates Transforming Growth Factor-β Signaling in Murine Hepatic Stellate Cells
inferred← citeshttps://doi.org/10.1016/j.antiviral.2014.03.012openalex-snapshot
Reversal, maintenance or progression: What happens to the liver after a virologic cure of hepatitis C?
inferred← citeshttps://doi.org/10.1016/j.aohep.2024.101565openalex-snapshot
Ethanol with thioacetamide murine model of alcoholic liver disease identifies hepatic pathways as targets for the human disease
inferred← citeshttps://doi.org/10.1016/j.apsb.2021.12.016openalex-snapshot
Design of a highly potent GLP-1R and GCGR dual-agonist for recovering hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.bbadis.2012.11.002openalex-snapshot
Extracellular matrix degradation in liver fibrosis: Biochemistry and regulation
inferred← citeshttps://doi.org/10.1016/j.bbadis.2012.11.015openalex-snapshot
Resident mesenchymal cells and fibrosis
inferred← citeshttps://doi.org/10.1016/j.bbadis.2013.02.019openalex-snapshot
Origins and functions of liver myofibroblasts
inferred← citeshttps://doi.org/10.1016/j.bbadis.2018.08.009openalex-snapshot
Animal models for hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.bbadis.2019.06.009openalex-snapshot
Nicotinamide riboside, an NAD+ precursor, attenuates the development of liver fibrosis in a diet-induced mouse model of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.bbadis.2025.167802openalex-snapshot
Differentiation-inducing factor-1 ameliorates liver fibrosis through the reversion of activated hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2023.119569openalex-snapshot
Bromodomain protein 4 is a key molecular driver of TGFβ1-induced hepatic stellate cell activation
inferred← citeshttps://doi.org/10.1016/j.bbcan.2020.188356openalex-snapshot
Fibrosis and cancer: A strained relationship
inferred← citeshttps://doi.org/10.1016/j.bbrc.2017.08.164openalex-snapshot
Hedgehog signaling inhibitor GANT61 induces endoplasmic reticulum stress-mediated protective autophagy in hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.11.153openalex-snapshot
CDH11 promotes liver fibrosis via activation of hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2021.05.035openalex-snapshot
GPRC5B promotes collagen production in myofibroblasts
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152011openalex-snapshot
Hepatic stellate cell-derived Delta-like 1 is dispensable for injury-induced liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115497openalex-snapshot
BRD4 promotes hepatic stellate cells activation and hepatic fibrosis via mediating P300/H3K27ac/PLK1 axis
inferred← citeshttps://doi.org/10.1016/j.bcp.2023.115740openalex-snapshot
Targeting collagen homeostasis for the treatment of liver fibrosis: Opportunities and challenges
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2022.07.018openalex-snapshot
A boronate-based modular assembly nanosystem to block the undesirable crosstalk between hepatic stellate cells and Kupffer cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2021.105933openalex-snapshot
Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2015.11.026openalex-snapshot
Novel human hepatic organoid model enables testing of drug-induced liver fibrosis in vitro
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2018.07.008openalex-snapshot
Laminin-521 promotes quiescence in isolated stellate cells from rat liver
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2020.120611openalex-snapshot
3D culture of HepaRG cells in GelMa and its application to bioprinting of a multicellular hepatic model
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2023.122232openalex-snapshot
Dually fibronectin/CD44-mediated nanoparticles targeted disrupt the Golgi apparatus and inhibit the hedgehog signaling in activated hepatic stellate cells to alleviate liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2012.10.002openalex-snapshot
Clearance of activated stellate cells for hepatic fibrosis regression: Molecular basis and translational potential
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.08.037openalex-snapshot
Nrf2 activation is required for curcumin to induce lipocyte phenotype in hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2019.109516openalex-snapshot
Extract of Averrhoacarambola L. (Oxalidaceae) roots ameliorates carbon tetrachloride-induced hepatic fibrosis in rats
inferred← citeshttps://doi.org/10.1016/j.biopha.2020.109932openalex-snapshot
Total phenolic extract of Euscaphis konishii hayata Pericarp attenuates carbon tetrachloride (CCl4)-induced liver fibrosis in mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117178openalex-snapshot
Emerging role of BMPs/BMPR2 signaling pathway in treatment for pulmonary fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2024.117737openalex-snapshot
An anti-RAGE chimeric antibody alleviates CCl4-induced liver fibrosis via RAGE/NF-kB pathway in mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118249openalex-snapshot
Therapeutic implications of obeticholic acid, a farnesoid X receptor agonist, in the treatment of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119883openalex-snapshot
Fibroblast activation protein-α in liver fibrosis and hepatocarcinogenesis: Stromal remodeling, molecular imaging, and theranostic targeting
inferred← citeshttps://doi.org/10.1016/j.bpg.2017.04.005openalex-snapshot
Reversal of liver fibrosis: From fiction to reality
inferred← citeshttps://doi.org/10.1016/j.canlet.2016.03.047openalex-snapshot
Hepatocellular carcinoma: Mouse models and the potential roles of proteases
inferred← citeshttps://doi.org/10.1016/j.carbpol.2023.121659openalex-snapshot
Structural characterization of an inulin neoseries-type fructan from Ophiopogonis Radix and the therapeutic effect on liver fibrosis in vivo
inferred← citeshttps://doi.org/10.1016/j.ccell.2016.09.004openalex-snapshot
p62/SQSTM1 by Binding to Vitamin D Receptor Inhibits Hepatic Stellate Cell Activity, Fibrosis, and Liver Cancer
inferred← citeshttps://doi.org/10.1016/j.ccell.2016.09.013openalex-snapshot
p62 in Liver Disease: Good Guy or Bad Guy?
inferred← citeshttps://doi.org/10.1016/j.ccell.2023.02.015openalex-snapshot
Activated fibroblasts in cancer: Perspectives and challenges
inferred← citeshttps://doi.org/10.1016/j.cej.2026.182254openalex-snapshot
Antioxidant biosurfactant-integrated stem cell nanovesicles for fibroblast reprogramming and membrane-protective wound healing
inferred← citeshttps://doi.org/10.1016/j.cell.2014.08.007openalex-snapshot
Vitamin D Receptor-Mediated Stromal Reprogramming Suppresses Pancreatitis and Enhances Pancreatic Cancer Therapy
inferred← citeshttps://doi.org/10.1016/j.cell.2026.02.001openalex-snapshot
Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.cellimm.2025.105024openalex-snapshot
Follicular helper T cells and fibrotic diseases
inferred← citeshttps://doi.org/10.1016/j.cellsig.2025.111774openalex-snapshot
Circadian clock regulation of myofibroblast fate
inferred← citeshttps://doi.org/10.1016/j.cellsig.2026.112487openalex-snapshot
KNDC1 attenuates fibrosis in nonalcoholic fatty liver disease by inhibiting glycolysis in hepatic stellate cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2023.112669openalex-snapshot
Reelin through the years: From brain development to inflammation
inferred← citeshttps://doi.org/10.1016/j.clinre.2015.05.017openalex-snapshot
Morphogen-related therapeutic targets for liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.clinre.2015.06.011openalex-snapshot
New therapies for hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.clinre.2015.06.015openalex-snapshot
Reversibility of liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.cmet.2020.10.026openalex-snapshot
The Power of Plasticity—Metabolic Regulation of Hepatic Stellate Cells
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2024.114376openalex-snapshot
Dual-ligand-functionalized nanostructured lipid carriers as a novel dehydrocavidine delivery system for liver fibrosis therapy
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2022.103902openalex-snapshot
Deciphering the possible reciprocal loop between hepatic stellate cells and cancer cells in the tumor microenvironment of the liver
inferred← citeshttps://doi.org/10.1016/j.cveq.2026.04.003openalex-snapshot
Equine Liver Histopathology
inferred← citeshttps://doi.org/10.1016/j.diff.2016.05.009openalex-snapshot
Genetic tools for identifying and manipulating fibroblasts in the mouse
inferred← citeshttps://doi.org/10.1016/j.diff.2016.07.001openalex-snapshot
The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis
inferred← citeshttps://doi.org/10.1016/j.dld.2021.07.006openalex-snapshot
Intercellular crosstalk of liver sinusoidal endothelial cells in liver fibrosis, cirrhosis and hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.drudis.2015.10.015openalex-snapshot
Emerging therapeutic targets for the treatment of hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.ebiom.2016.05.040openalex-snapshot
Progressive Fibrosis Is Driven by Genetic Predisposition, Allo-immunity, and Inflammation in Pediatric Liver Transplant Recipients
inferred← citeshttps://doi.org/10.1016/j.ebiom.2018.12.017openalex-snapshot
Reversion of in vivo fibrogenesis by novel chromone scaffolds
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.02.019openalex-snapshot
Nitro-fatty acids protect against steatosis and fibrosis during development of nonalcoholic fatty liver disease in mice
inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115596openalex-snapshot
Design, synthesis and anti-hepatic fibrosis activity of novel diphenyl vitamin D receptor agonists
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.117281openalex-snapshot
Recent advances in small molecule design strategies against hepatic fibrosis
inferred← citeshttps://doi.org/10.1016/j.ejphar.2019.172730openalex-snapshot
Naringenin attenuates the progression of liver fibrosis via inactivation of hepatic stellate cells and profibrogenic pathways
inferred← citeshttps://doi.org/10.1016/j.etp.2013.05.008openalex-snapshot
Characterization of glial fibrillary acidic protein (GFAP)-expressing hepatic stellate cells and myofibroblasts in thioacetamide (TAA)-induced rat liver injury
inferred← citeshttps://doi.org/10.1016/j.exer.2015.07.009openalex-snapshot
Myofibroblasts
inferred← citeshttps://doi.org/10.1016/j.gastha.2026.100917openalex-snapshot
Lecithin-Retinol Acyltransferase-Cre Exhibits Widespread Expression Beyond Hepatic Stellate Cells Across Multiple Tissues
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2025.147642openalex-snapshot
Roles and potential mechanisms of hepatic stellate cells activation mediated by epigenetics through insulin like growth factor 1 and receptor: A review
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