On the public citation graph
Inhibition of NF-κB Activation by 4-Hydroxynonenal Contributes to Liver Injury in a Mouse Model of Alcoholic Liver Disease
0 signed · 88 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/hep.1840090302openalex-snapshot
Increased tumor necrosis factor production by monocytes in alcoholic hepatitis
inferredcites →https://doi.org/10.1002/hep.1840130211openalex-snapshot
Circulating tumor necrosis factor, interleukin-1 and interleukin-6 concentrations in chronic alcoholic patients
inferredcites →https://doi.org/10.1002/hep.20412openalex-snapshot
S-adenosylhomocysteine sensitizes to TNF-? hepatotoxicity in mice and liver cells: A possible etiological factor in alcoholic liver disease
inferredcites →https://doi.org/10.1002/hep.22074openalex-snapshot
Inhibition of adiponectin production by homocysteine: A potential mechanism for alcoholic liver disease
inferredcites →https://doi.org/10.1002/hep.24599openalex-snapshot
An essential role for monocyte chemoattractant protein-1 in alcoholic liver injury: Regulation of proinflammatory cytokines and hepatic steatosis in mice
inferredcites →https://doi.org/10.1002/hep.510250216openalex-snapshot
Effect of Chronic Ethanol Feeding on Lipid Peroxidation and Protein Oxidation in Relation to Liver Pathology
inferredcites →https://doi.org/10.1002/hep.510260119openalex-snapshot
Association of a tumor necrosis factor promoter polymorphism with susceptibility to alcoholic steatohepatitis
inferredcites →https://doi.org/10.1002/hep.510260621openalex-snapshot
Antibodies to tumor necrosis factor alfa attenuate hepatic necrosis and inflammation caused by chronic exposure to ethanol in the rat
inferredcites →https://doi.org/10.1002/hep.510260622openalex-snapshot
Dietary saturated fatty acids down-regulate cyclooxygenase-2 and tumor necrosis factor alfa and reverse fibrosis in alcohol-induced liver disease in the rat
inferredcites →https://doi.org/10.1002/hep.510270518openalex-snapshot
Increased lipid peroxidation and impaired antioxidant enzyme function is associated with pathological liver injury in experimental alcoholic liver disease in rats fed diets high in corn oil and fish oil
inferredcites →https://doi.org/10.1006/exmp.1993.1006openalex-snapshot
Effect of Ethanol on Cytochrome P450 2E1 (CYP2E1), Lipid Peroxidation, and Serum Protein Adduct Formation in Relation to Liver Pathology Pathogenesis
inferredcites →https://doi.org/10.1016/0005-2760(84)90219-4openalex-snapshot
Cytotoxic aldehydes originating from the peroxidation of liver microsomal lipids
inferredcites →https://doi.org/10.1016/0891-5849(91)90192-6openalex-snapshot
Chemistry and biochemistry of 4-hydroxynonenal, malonaldehyde and related aldehydes
inferredcites →https://doi.org/10.1016/0929-7855(94)00027-aopenalex-snapshot
Detection of 4-hydroxynonenal (HNE) as a physiological component in human plasma
inferredcites →https://doi.org/10.1016/j.alcohol.2005.03.013openalex-snapshot
Alcohol, iron-associated oxidative stress, and cancer
inferredcites →https://doi.org/10.1016/j.freeradbiomed.2004.05.011openalex-snapshot
Induction of endothelial iNOS by 4-hydroxyhexenal through NF-κB activation
inferredcites →https://doi.org/10.1016/j.taap.2010.08.025openalex-snapshot
Xanthine oxidase-derived reactive oxygen species mediate 4-oxo-2-nonenal-induced hepatocyte cell death
inferredcites →https://doi.org/10.1016/s0009-9120(99)00057-0openalex-snapshot
Effect of ethanol on tumor necrosis factor signaling during liver regeneration
inferredcites →https://doi.org/10.1016/s0016-5085(98)70034-4openalex-snapshot
Selective glutathione depletion of mitochondria by ethanol sensitizes hepatocytes to tumor necrosis factor
inferredcites →https://doi.org/10.1016/s0016-5085(99)70354-9openalex-snapshot
Essential role of tumor necrosis factor α in alcohol-induced liver injury in mice
inferredcites →https://doi.org/10.1016/s0022-3565(25)38746-xopenalex-snapshot
The oral iron chelator, 1,2-dimethyl-3-hydroxypyrid-4-one reduces hepatic-free iron, lipid peroxidation and fat accumulation in chronically ethanol-fed rats.
inferredcites →https://doi.org/10.1016/s1074-7613(00)80042-4openalex-snapshot
Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice
inferredcites →https://doi.org/10.1053/he.2000.7013openalex-snapshot
Ethanol potentiates tumor necrosis factor-α cytotoxicity in hepatoma cells and primary rat hepatocytes by promoting induction of the mitochondrial permeability transition
inferredcites →https://doi.org/10.1055/s-0029-1214370openalex-snapshot
Oxidative Stress and Alcoholic Liver Disease
inferredcites →https://doi.org/10.1074/jbc.274.17.11611openalex-snapshot
4-Hydroxynonenal Prevents NF-κB Activation and Tumor Necrosis Factor Expression by Inhibiting IκB Phosphorylation and Subsequent Proteolysis
inferredcites →https://doi.org/10.1074/jbc.m101632200openalex-snapshot
Chronic Ethanol Exposure Potentiates Lipopolysaccharide Liver Injury Despite Inhibiting Jun N-terminal Kinase and Caspase 3 Activation
inferredcites →https://doi.org/10.1093/jn/134.4.904openalex-snapshot
Dietary Saturated Fat Reduces Alcoholic Hepatotoxicity in Rats by Altering Fatty Acid Metabolism and Membrane Composition
inferredcites →https://doi.org/10.1093/jn/138.3.497openalex-snapshot
Mammalian Sirtuin 1 Is Involved in the Protective Action of Dietary Saturated Fat against Alcoholic Fatty Liver in Mice
inferredcites →https://doi.org/10.1111/j.1365-2036.2004.01881.xopenalex-snapshot
Current management of alcoholic liver disease
inferredcites →https://doi.org/10.1111/j.1530-0277.1990.tb00482.xopenalex-snapshot
Plasma Tumor Necrosis Factor α Predicts Decreased Long‐Term Survival in Severe Alcoholic Hepatitis
inferredcites →https://doi.org/10.1111/j.1530-0277.1998.tb03637.xopenalex-snapshot
Increased Circulating Products of Lipid Peroxidation in Patients with Alcoholic Liver Disease
inferredcites →https://doi.org/10.1111/j.1530-0277.2006.00012.xopenalex-snapshot
Moderate Alcohol Intake in Humans Attenuates Monocyte Inflammatory Responses: Inhibition of Nuclear Regulatory Factor Kappa B and Induction of Interleukin 10
inferredcites →https://doi.org/10.1172/jci0215295openalex-snapshot
Hepatocyte-specific inhibition of NF-κB leads to apoptosis after TNF treatment, but not after partial hepatectomy
inferredcites →https://doi.org/10.1172/jci118077openalex-snapshot
Experimental liver cirrhosis induced by alcohol and iron.
inferredcites →https://doi.org/10.1172/jci15295openalex-snapshot
Hepatocyte-specific inhibition of NF-κB leads to apoptosis after TNF treatment, but not after partial hepatectomy
inferredcites →https://doi.org/10.3748/wjg.v9.i1.125openalex-snapshot
N-acetylcysteine attenuates alcohol-induced oxidative stress in the rat
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4794612openalex-extracted
Molecular Mechanism of 4-Hydroxynonenal Induced Cell Death
inferred← citeshttps://doi.org/10.1002/cbf.70169openalex-snapshot
ALDH2 and NFκB Activation Restores VEGFR2 Expression and Angiogenesis Impaired by 4‐HNE in Coronary Endothelial Cells
inferred← citeshttps://doi.org/10.1002/hep.29229openalex-snapshot
Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity
inferred← citeshttps://doi.org/10.1007/s00018-018-2852-6openalex-snapshot
Targeting Nrf-2 is a promising intervention approach for the prevention of ethanol-induced liver disease
inferred← citeshttps://doi.org/10.1007/s12272-026-01611-2openalex-snapshot
Leptin sensitizes hepatocytes to endotoxin toxicity via interleukin-1β signaling and drives adaptive immune activation in the liver
inferred← citeshttps://doi.org/10.1007/s40362-013-0015-6openalex-snapshot
Regulation of Glutathione in Health and Disease with Special Emphasis on Chronic Alcoholism and Hyperglycaemia Mediated Liver Injury: A Brief Perspective
inferred← citeshttps://doi.org/10.1016/b978-0-12-811297-7.00032-9openalex-snapshot
Transcriptional Factor Modulation by Lipid Peroxidation-Derived Aldehydes
inferred← citeshttps://doi.org/10.1016/b978-0-12-823371-9.00006-xopenalex-snapshot
Dietary oxidized lipids
inferred← citeshttps://doi.org/10.1016/j.abb.2016.11.003openalex-snapshot
Signaling by 4-hydroxy-2-nonenal: Exposure protocols, target selectivity and degradation
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.11.002openalex-snapshot
Induction of Cyp2e1 contributes to asparaginase-induced hepatocyte sensitization to lipotoxicity
inferred← citeshttps://doi.org/10.1016/j.bbalip.2013.09.004openalex-snapshot
tert-Butylhydroquinone (tBHQ) protects hepatocytes against lipotoxicity via inducing autophagy independently of Nrf2 activation
inferred← citeshttps://doi.org/10.1016/j.cbi.2026.112012openalex-snapshot
β-Nicotinamide mononucleotide prevents senescence and lipid accumulation in hepatic stellate cells by restoring SIRT1 function
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.11.010openalex-snapshot
Pro-apoptotic effects of lipid oxidation products: HNE at the crossroads of NF-κB pathway and anti-apoptotic Bcl-2
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2016.11.032openalex-snapshot
4-hydroxynonenal-mediated signaling and aging
inferred← citeshttps://doi.org/10.1016/j.freeradbiomed.2017.01.023openalex-snapshot
Lipid oxidation products in the pathogenesis of non-alcoholic steatohepatitis
inferred← citeshttps://doi.org/10.1016/j.intimp.2013.05.023openalex-snapshot
Puerarin, isolated from Kudzu root (Willd.), attenuates hepatocellular cytotoxicity and regulates the GSK-3β/NF-κB pathway for exerting the hepatoprotection against chronic alcohol-induced liver injury in rats
inferred← citeshttps://doi.org/10.1016/j.intimp.2021.107777openalex-snapshot
Insights on the mechanisms of action of ozone in the medical therapy against COVID-19
inferred← citeshttps://doi.org/10.1016/j.jff.2016.02.019openalex-snapshot
Fisetin protects liver from binge alcohol-induced toxicity by mechanisms including inhibition of matrix metalloproteinases (MMPs) and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.jff.2017.09.056openalex-snapshot
Histidine-alleviated hepatocellular death in response to 4-hydroxynonenal contributes to the protection against high-fat diet-induced liver injury
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.11.011openalex-snapshot
Preventive effects of indole-3-carbinol against alcohol-induced liver injury in mice via antioxidant, anti-inflammatory, and anti-apoptotic mechanisms: Role of gut-liver-adipose tissue axis
inferred← citeshttps://doi.org/10.1016/j.jphs.2016.02.001openalex-snapshot
Celastrol, an NF-κB inhibitor, ameliorates hypercalciuria and articular cartilage lesions in a mouse model of secondary osteoporosis
inferred← citeshttps://doi.org/10.1016/j.prerep.2024.100018openalex-snapshot
Mirabegron alleviates fructose induced nonalcoholic fatty liver disease in rats: Insights into the underlying mechanisms
inferred← citeshttps://doi.org/10.1016/j.redox.2014.12.009openalex-snapshot
Steatosis-induced proteins adducts with lipid peroxidation products and nuclear electrophilic stress in hepatocytes
inferred← citeshttps://doi.org/10.1021/acs.jafc.2c00852openalex-snapshot
Upregulation of 4-Hydroxynonenal Contributes to the Negative Effect of n-6 Polyunsaturated Fatty Acid on Alcohol-Induced Liver Injury and Hepatic Steatosis
inferred← citeshttps://doi.org/10.1038/cdd.2013.138openalex-snapshot
Cell death and diseases related to oxidative stress:4-hydroxynonenal (HNE) in the balance
inferred← citeshttps://doi.org/10.1038/s41598-019-49262-2openalex-snapshot
Cerium oxide nanoparticles display antilipogenic effect in rats with non-alcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1039/c3mb70114jopenalex-snapshot
RNA-seq data analysis at the gene and CDS levels provides a comprehensive view of transcriptome responses induced by 4-hydroxynonenal
inferred← citeshttps://doi.org/10.1039/c9ra08976dopenalex-snapshot
Therapeutic potency of fermented field water-dropwort ( Oenanthe javanica (Blume) DC.) in ethanol-induced liver injury
inferred← citeshttps://doi.org/10.1039/d2fo03323bopenalex-snapshot
Monounsaturated fatty acid-enriched olive oil exacerbates chronic alcohol-induced hepatic steatosis and liver injury in C57BL/6J mice
inferred← citeshttps://doi.org/10.1080/15376516.2022.2127389openalex-snapshot
Acutely increased aquaporin-4 exhibits more potent protective effects in the cortex against single and repeated isoflurane-induced neurotoxicity in the developing rat brain
inferred← citeshttps://doi.org/10.1101/2022.12.07.519420openalex-snapshot
Aldo-Keto Reductase Family 1 Member A1 (AKR1A1) Deficiency Exacerbates Alcohol-Induced Hepatic Oxidative Stress, Inflammation, Steatosis, and Fibrosis
inferred← citeshttps://doi.org/10.1101/2025.11.24.690094openalex-snapshot
4-Hydroxynonenal suppresses IL-10 production during infection
inferred← citeshttps://doi.org/10.1126/sciadv.adt6195openalex-snapshot
Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease
inferred← citeshttps://doi.org/10.1128/9781555819194.ch45openalex-snapshot
Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages
inferred← citeshttps://doi.org/10.1128/microbiolspec.mchd-0044-2016openalex-snapshot
Glutathione and Glutathione Transferase Omega 1 as Key Posttranslational Regulators in Macrophages
inferred← citeshttps://doi.org/10.1139/cjpp-2017-0473openalex-snapshot
Capsaicin, the pungent principle of peppers, ameliorates alcohol-induced acute liver injury in mice via modulation of matrix metalloproteinases
inferred← citeshttps://doi.org/10.1155/2014/360438openalex-snapshot
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal
inferred← citeshttps://doi.org/10.1155/2019/5937326openalex-snapshot
4-Hydroxy-Trans-2-Nonenal in the Regulation of Anti-Oxidative and Pro-Inflammatory Signaling Pathways
inferred← citeshttps://doi.org/10.1165/rcmb.2014-0195ocopenalex-snapshot
The Lung-Liver Axis: A Requirement for Maximal Innate Immunity and Hepatoprotection during Pneumonia
inferred← citeshttps://doi.org/10.1186/s13578-024-01200-0openalex-snapshot
Aldo-keto reductase family 1 member A1 (AKR1A1) exerts a protective function in alcohol-associated liver disease by reducing 4-HNE accumulation and p53 activation
inferred← citeshttps://doi.org/10.1371/journal.pone.0186357openalex-snapshot
Danshen protects against early-stage alcoholic liver disease in mice via inducing PPARα activation and subsequent 4-HNE degradation
inferred← citeshttps://doi.org/10.1371/journal.pone.0225531openalex-snapshot
NF-κB-mediated regulation of rat CYP2E1 by two independent signaling pathways
inferred← citeshttps://doi.org/10.1371/journal.pone.0245799openalex-snapshot
Pharmacological inhibition of catalase induces peroxisome leakage and suppression of LPS induced inflammatory response in Raw 264.7 cell
inferred← citeshttps://doi.org/10.3389/fcvm.2022.842980openalex-snapshot
Salvia miltiorrhiza Bge. (Danshen) in the Treating Non-alcoholic Fatty Liver Disease Based on the Regulator of Metabolic Targets
inferred← citeshttps://doi.org/10.3389/fnagi.2020.00001openalex-snapshot
Electrophile Signaling and Emerging Immuno- and Neuro-modulatory Electrophilic Pharmaceuticals
inferred← citeshttps://doi.org/10.3389/fncel.2022.998512openalex-snapshot
Serum 4-hydroxynonenal associates with the recurrence of patients with primary cerebral infarction
inferred← citeshttps://doi.org/10.3389/fnut.2022.1026740openalex-snapshot
Dietary camellia seed oil attenuates liver injury in mice chronically exposed to alcohol
inferred← citeshttps://doi.org/10.3390/antiox12040829openalex-snapshot
Response of a Human Lens Epithelial Cell Line to Hyperglycemic and Oxidative Stress: The Role of Aldose Reductase
inferred← citeshttps://doi.org/10.3390/antiox13020232openalex-snapshot
Reactive Carbonyl Species and Protein Lipoxidation in Atherogenesis
inferred← citeshttps://doi.org/10.4103/mgr.medgasres-d-24-00005openalex-snapshot
Ozone: complicated effects in central nervous system diseases
inferred← citeshttps://doi.org/10.7150/ijbs.85028openalex-snapshot
N-Acetylcysteine overcomes epalrestat-mediated increase of toxic 4-hydroxy-2-nonenal and potentiates the anti-arthritic effect of epalrestat in AIA model
inferred← citeshttps://doi.org/10.71781/26251openalex-snapshot
Étude in vitro de l’implication des cytokines de type Th17 dans la fibrose hépatique
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.