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Post genomic analysis of permeases from the amino acid/auxin family in protozoan parasites
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
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Mammalian integral membrane receptors are homologous to facilitators and antiporters of yeast, fungi, and eubacteria
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Molecular cloning: A laboratory manual
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Trypanosoma gambiense: Membrane transport of amino acids
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Correlation between inhibition of growth and arginine transport of Leishmania donovani promastigotes in vitro by diamidines
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Amino-acid transport in Trypanosoma brucei
inferredcites →https://doi.org/10.1016/0166-6851(85)90073-8openalex-snapshot
In vitro differentiation of Trypanosoma cruzi under chemically defined conditions
inferredcites →https://doi.org/10.1016/0166-6851(87)90066-1openalex-snapshot
Two high affinity nucleoside transporters in Leishmania donovani
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A functional superfamily of sodium/solute symporters
inferredcites →https://doi.org/10.1016/0305-0491(76)90318-7openalex-snapshot
Proline metabolism in Trypanosoma cruzi epimastigotes
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The importance of arginine in evolution
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Nucleotide sequence of the Saccharomyces cerevisiae PUT4 proline-permease-encoding gene: similarities between CAN1, HIP1 and PUT4 permeases
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Phosphoric Acid Anhydrides and Other Energy-Rich Compounds
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COMPARATIVE BIOCHEMISTRY
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Biochemical characterization of a low-affinity arginine permease from the parasite Trypanosoma cruzi
inferredcites →https://doi.org/10.1016/s0005-2736(98)00196-5openalex-snapshot
The amino acid/auxin:proton symport permease family1The accompanying review paper ‘Phylogenetic characterization of novel transport protein families revealed by genome analysis’ by M.H. Saier Jr. et al. will be published in Biochim. Biophys. Acta, Vol. 1422/1, February 1999 issue.1
inferredcites →https://doi.org/10.1016/s0014-5793(02)03157-5openalex-snapshot
Arginine metabolism in Trypanosoma cruzi is coupled to parasite stage and replication
inferredcites →https://doi.org/10.1016/s0014-5793(03)01171-2openalex-snapshot
Arginine kinase overexpression improves Trypanosoma cruzi survival capability
inferredcites →https://doi.org/10.1016/s0022-1910(00)00170-0openalex-snapshot
Ionic composition of the rectal contents and excreta of the reduviid bug Triatoma infestans
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Basic Local Alignment Search Tool
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Point mutations in a nucleoside transporter gene from Leishmania donovani confer drug resistance and alter substrate selectivity
inferredcites →https://doi.org/10.1074/jbc.272.48.30552openalex-snapshot
Topology of NAT2, a Prototypical Example of a New Family of Amino Acid Transporters
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Cloning and Functional Expression of a Gene Encoding a P1 Type Nucleoside Transporter from Trypanosoma brucei
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Trypanosoma cruzi Arginine Kinase Characterization and Cloning
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The Transporter Classification (TC) System, 2002
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Applications of InterPro in protein annotation and genome analysis
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Tree View: An application to display phylogenetic trees on personal computers
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Comparative accuracy of methods for protein sequence similarity search.
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Automated assembly of protein blocks for database searching
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Consed: A Graphical Tool for Sequence Finishing
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l-Proline is essential for the intracellular differentiation of Trypanosoma cruzi
inferredcites →https://doi.org/10.1111/j.1550-7408.1999.tb05132.xopenalex-snapshot
L‐Arginine Uptake and L‐Phosphoarginine Synthesis In Trypanosoma Cruzi
inferredcites →https://doi.org/10.1111/j.1550-7408.2002.tb00225.xopenalex-snapshot
Active Transport of L‐Proline in Trypanosoma cruzi
inferredcites →https://doi.org/10.1111/j.1550-7408.2002.tb00346.xopenalex-snapshot
Arginine Kinase: A Common Feature for Management of Energy Reserves in African and American Flagellated Trypanosomatids
inferredcites →https://doi.org/10.1111/j.1574-6968.2004.tb09630.xopenalex-snapshot
Biochemical characterization of a low-affinity arginine permease from the parasiteTrypanosoma cruzi
inferredcites →https://doi.org/10.1126/science.285.5425.242openalex-snapshot
A Nucleoside Transporter from Trypanosoma brucei Involved in Drug Resistance
inferredcites →https://doi.org/10.1146/annurev.mi.27.100173.002023openalex-snapshot
Biology of Trypanosoma Cruzi
inferredcites →https://doi.org/10.1146/annurev.physiol.63.1.289openalex-snapshot
Evolution and Physiological Roles of Phosphagen Systems
inferredcites →https://doi.org/10.1385/1-59259-192-2:221openalex-snapshot
The Use of CLUSTAL W and CLUSTAL X for Multiple Sequence Alignment
inferredcites →https://doi.org/10.1590/s0074-02761909000200008openalex-snapshot
Nova tripanozomiaze humana: estudos sobre a morfolojia e o ciclo evolutivo do Schizotrypanum cruzi n. gen., n. sp., ajente etiolojico de nova entidade morbida do homem
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Unravelling the Mechanisms of Proline Analogues Against Trypanosoma Cruzi
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Drug Discovery and Development for Kinetoplastid Diseases
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Drugs and Transporters in Kinetoplastid Protozoa
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Trypanosoma cruzi Polyamine Transporter: Its Role on Parasite Growth and Survival Under Stress Conditions
inferred← citeshttps://doi.org/10.1007/s00726-010-0812-zopenalex-snapshot
Lysine transporters in human trypanosomatid pathogens
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Effectiveness of the repurposed drug isotretinoin in an experimental murine model of Chagas disease
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Mechanisms of resistance of Trypanosoma cruzi to benznidazole and nifurtimox: Molecular implications and multifaceted impact
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Evaluation of proline analogs as trypanocidal agents through the inhibition of a Trypanosoma cruzi proline transporter
inferred← citeshttps://doi.org/10.1016/j.bbrc.2006.03.215openalex-snapshot
Molecular and functional characterization of a spermidine transporter (TcPAT12) from Trypanosoma cruzi
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Identification of cisapride as new inhibitor of putrescine uptake in Trypanosoma cruzi by combined ligand- and structure-based virtual screening
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Characterisation of a developmentally regulated amino acid transporter gene fromLeishmania amazonensis
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Aspartate transport and metabolism in the protozoan parasiteTrypanosoma cruzi
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Biochemical characterization of the glutamate transport in Trypanosoma cruzi
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Biochemical characterization of serine transport in Leishmania (Leishmania) amazonensis
inferred← citeshttps://doi.org/10.1016/j.molbiopara.2009.07.006openalex-snapshot
Glucose uptake in the mammalian stages of Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1016/j.molbiopara.2018.07.007openalex-snapshot
L-Glutamine uptake is developmentally regulated and is involved in metacyclogenesis in Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1016/s0065-308x(06)63002-9openalex-snapshot
Targeting of Toxic Compounds to the Trypanosome's Interior
inferred← citeshttps://doi.org/10.1042/bcj20210428openalex-snapshot
Higher expression of proline dehydrogenase altered mitochondrial function and increased Trypanosoma cruzi differentiation in vitro and in the insect vector
inferred← citeshttps://doi.org/10.1042/bj20110362openalex-snapshot
Polyamine homoeostasis as a drug target in pathogenic protozoa: peculiarities and possibilities
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Elucidating the Transport Mechanisms and Metabolic Roles of Serine, Threonine, and Glycine in Trypanosoma cruzi
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A novel high‐affinity arginine transporter from the human parasitic protozoan Leishmania donovani
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Active Transport of Glutamate in Leishmania (Leishmania) amazonensis
inferred← citeshttps://doi.org/10.1111/j.1574-6968.2008.01467.xopenalex-snapshot
Characterization ofTrypanosoma cruzil-cysteine transport mechanisms and their adaptive regulation
inferred← citeshttps://doi.org/10.1111/j.1574-6968.2010.01936.xopenalex-snapshot
Trypanosoma cruziamino acid transporter TcAAAP411 mediates arginine uptake in yeasts
inferred← citeshttps://doi.org/10.1111/jeu.12219openalex-snapshot
The Uptake of GABA in Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1111/jeu.12278openalex-snapshot
Biochemical Characterization of Branched Chain Amino Acids Uptake in Trypanosoma cruzi
inferred← citeshttps://doi.org/10.1111/jeu.12295openalex-snapshot
Trypanosoma cruzi Proline Transport Presents a Cell Density‐dependent Regulation
inferred← citeshttps://doi.org/10.1128/msphere.00983-24openalex-snapshot
The role of l -serine and l -threonine in the energy metabolism and nutritional stress response of Trypanosoma cruzi
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Uptake of l -Alanine and Its Distinct Roles in the Bioenergetics of Trypanosoma cruzi
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Análise do transporte de glutamato e GABA em epimastigotas de Trypanosoma cruzi.
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Papel da Alanine e da Alanine racemase no metabolismo do >i /i<
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Metabolismo dos aminoácidos ramificados e sua participação na modulação da diferenciação em Trypanosoma cruzi.
inferred← citeshttps://doi.org/10.1186/1471-2091-12-46openalex-snapshot
The major leucyl aminopeptidase of Trypanosoma cruzi (LAPTc) assembles into a homohexamer and belongs to the M17 family of metallopeptidases
inferred← citeshttps://doi.org/10.1186/1471-2148-7-26openalex-snapshot
Origins of amino acid transporter loci in trypanosomatid parasites.
inferred← citeshttps://doi.org/10.1186/s13071-015-0950-yopenalex-snapshot
Identification and functional characterization of a novel arginine/ornithine transporter, a member of a cationic amino acid transporter subfamily in the Trypanosoma cruzi genome
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Correction: On the Evolution of Hexose Transporters in Kinetoplastid Potozoans
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Trypanocidal Effect of Isotretinoin through the Inhibition of Polyamine and Amino Acid Transporters in Trypanosoma cruzi
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The superfamily keeps growing: Identification in trypanosomatids of RibJ, the first riboflavin transporter family in protists
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Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069
inferred← citeshttps://doi.org/10.1371/journal.pone.0032760openalex-snapshot
Cationic Amino Acid Uptake Constitutes a Metabolic Regulation Mechanism and Occurs in the Flagellar Pocket of Trypanosoma cruzi
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On the Evolution of Hexose Transporters in Kinetoplastid Potozoans
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Proline Modulates the Trypanosoma cruzi Resistance to Reactive Oxygen Species and Drugs through a Novel D, L-Proline Transporter
inferred← citeshttps://doi.org/10.17760/d20328152openalex-snapshot
Chemical modifications for activity and property optimization
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Metabolite Transporters in Trypanosomatid Parasites: Promising Therapeutic Targets But… How to Deal with Them?
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The Thiol-polyamine Metabolism of Trypanosoma cruzi: Molecular Targets and Drug Repurposing Strategies
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Amino Acid and Polyamine Membrane Transporters in Trypanosoma cruzi: Biological Function and Evaluation as Drug Targets
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Proline transport inhibitors trigger differential responses in Trypanosoma cruzi growth inhibition
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Unravelling the effects of proline analogues against Trypanosoma cruzi
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Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing
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The potential of the antifungal nystatin to be repurposed to fight the protozoan Trypanosoma cruzi
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Transport proteins of parasitic protists and their role in nutrient salvage
inferred← citeshttps://doi.org/10.3390/insects12080746openalex-snapshot
Genome-Wide Analysis of the Amino Acid Auxin Permease (AAAP) Gene Family and Identification of an AAAP Gene Associated with the Growth and Reproduction of the Brown Planthopper, Nilaparvata lugens (Stål)
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The Uptake and Metabolism of Amino Acids, and Their Unique Role in the Biology of Pathogenic Trypanosomatids
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