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Chemistry and biology of ophiobolin A and its congeners
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/anie.201104447openalex-snapshot
Convergent Total Synthesis of (+)‐Ophiobolin A
inferredcites →https://doi.org/10.1002/chem.201204119openalex-snapshot
Enantioselective Total Synthesis of (+)‐Ophiobolin A
inferredcites →https://doi.org/10.1002/hlca.201000283openalex-snapshot
Ophiobolin Sesterterpenoids and Pyrrolidine Alkaloids from the Sponge‐Derived Fungus Aspergillus ustus
inferredcites →https://doi.org/10.1007/bf01922453openalex-snapshot
Phytotoxins and their involvement in plant diseases. Introduction
inferredcites →https://doi.org/10.1007/bf01922458openalex-snapshot
Non-host-selective fungal phytotoxins: Biochemical aspects of their mode of action
inferredcites →https://doi.org/10.1007/s11095-014-1386-3openalex-snapshot
Incorporation of Ophiobolin A into Novel Chemoembolization Particles for Cancer Cell Treatment
inferredcites →https://doi.org/10.1016/0968-0896(96)00036-3openalex-snapshot
Ophiobolin M and analogues, noncompetitive inhibitors of ivermectin binding with nematocidal activity
inferredcites →https://doi.org/10.1016/j.bmcl.2011.10.079openalex-snapshot
The novel agent ophiobolin O induces apoptosis and cell cycle arrest of MCF-7 cells through activation of MAPK signaling pathways
inferredcites →https://doi.org/10.1016/j.bmcl.2013.04.034openalex-snapshot
3-Anhydro-6-hydroxy-ophiobolin A, a new sesterterpene inhibiting the growth of methicillin-resistant Staphylococcus aureus and inducing the cell death by apoptosis on K562, from the phytopathogenic fungus Bipolaris oryzae
inferredcites →https://doi.org/10.1016/j.bmcl.2015.08.066openalex-snapshot
Fungal metabolite ophiobolin A as a promising anti-glioma agent: In vivo evaluation, structure–activity relationship and unique pyrrolylation of primary amines
inferredcites →https://doi.org/10.1016/j.fitote.2013.08.002openalex-snapshot
Ophiobolins P–T, five new cytotoxic and antibacterial sesterterpenes from the endolichenic fungus Ulocladium sp.
inferredcites →https://doi.org/10.1016/j.phytochem.2006.07.016openalex-snapshot
Ophiobolin E and 8-epi-ophiobolin J produced by Drechslera gigantea, a potential mycoherbicide of weedy grasses
inferredcites →https://doi.org/10.1016/j.tet.2004.05.021openalex-snapshot
Cytotoxic sesterterpenes, 6-epi-ophiobolin G and 6-epi-ophiobolin N, from marine derived fungus Emericella variecolor GF10
inferredcites →https://doi.org/10.1016/s0021-9258(17)43208-xopenalex-snapshot
Ophiobolin A. A natural product inhibitor of calmodulin.
inferredcites →https://doi.org/10.1016/s0024-3205(00)00668-8openalex-snapshot
The biology of ophiobolins
inferredcites →https://doi.org/10.1016/s0040-4020(01)96148-4openalex-snapshot
Structure and conformation of ophiobolin K and 6- epiophiobolin K from Aspergillus ustus as a nematocidal agent.
inferredcites →https://doi.org/10.1016/s0040-4039(00)72395-1openalex-snapshot
The constitution of cochliobolin
inferredcites →https://doi.org/10.1016/s0040-4039(00)72403-8openalex-snapshot
The structure of zizannin-A and -B, C25-terpenoids isolated from
inferredcites →https://doi.org/10.1016/s0040-4039(01)00682-7openalex-snapshot
Regioselective lithiations of a pterocarpan skeleton: the first synthesis of (±)-4′-dehydroxycabenegrin A-I
inferredcites →https://doi.org/10.1016/s0040-4039(01)85110-8openalex-snapshot
A new natural ophiobolin
inferredcites →https://doi.org/10.1016/s0040-4039(01)89701-xopenalex-snapshot
The structure of cephalonic acid, a pentaprenyl terpenoid
inferredcites →https://doi.org/10.1016/s0040-4039(01)89702-1openalex-snapshot
The chemical transformation of cephalonic acid
inferredcites →https://doi.org/10.1016/s0040-4039(01)99159-2openalex-snapshot
The isolation of an acyclic C25-isoprenoid alcohol, geranylnerolidol, and a new ophiobolin
inferredcites →https://doi.org/10.1016/s0040-4039(01)99717-5openalex-snapshot
Isolation and constitution of cochliobolin b
inferredcites →https://doi.org/10.1021/acs.jnatprod.7b00335openalex-snapshot
Ophiobolins from the Mangrove Fungus Aspergillus ustus
inferredcites →https://doi.org/10.1021/ja00189a069openalex-snapshot
Total synthesis of (+)-ophiobolin C
inferredcites →https://doi.org/10.1021/ja00949a061openalex-snapshot
The Structure of Ophiobolin, a C25 Terpenoid Having a Novel Skeleton
inferredcites →https://doi.org/10.1021/jf00124a019openalex-snapshot
Ophiobolins G and H: new fungal metabolites from a novel source, Aspergillus ustus
inferredcites →https://doi.org/10.1021/jf052843lopenalex-snapshot
Herbicidal Potential of Ophiobolins Produced by Drechslera gigantea
inferredcites →https://doi.org/10.1021/jo00245a008openalex-snapshot
Some new phytotoxic ophiobolins produced by Drechslera oryzae
inferredcites →https://doi.org/10.1021/np50065a046openalex-snapshot
3-Anhydroophiobolin A and 3-Anhydro-6-epi-ophiobolin A, Phytotoxic Metabolites of the Johnson Grass Pathogen Bipolaris sorghicola
inferredcites →https://doi.org/10.1021/np50115a009openalex-snapshot
Microbial Metabolites of Ophiobolin A and Antimicrobial Evaluation of Ophiobolins
inferredcites →https://doi.org/10.1021/np980462eopenalex-snapshot
Characterization of 6-epi-3-Anhydroophiobolin B from Cochliobolus heterostrophus
inferredcites →https://doi.org/10.1038/cddis.2013.85openalex-snapshot
Ophiobolin A induces paraptosis-like cell death in human glioblastoma cells by decreasing BKCa channel activity
inferredcites →https://doi.org/10.1038/onc.2016.59openalex-snapshot
Cancer stem cell drugs target K-ras signaling in a stemness context
inferredcites →https://doi.org/10.1038/sj.cdd.4401465openalex-snapshot
Paraptosis: mediation by MAP kinases and inhibition by AIP-1/Alix
inferredcites →https://doi.org/10.1039/c2ra22701kopenalex-snapshot
Terretonin, ophiobolin, and drimaneterpenes with absolute configurations from an algicolous Aspergillus ustus
inferredcites →https://doi.org/10.1039/c6ob01418fopenalex-snapshot
Single dish gradient screening of small molecule localization
inferredcites →https://doi.org/10.1073/pnas.84.10.3081openalex-snapshot
Phytotoxins from the pathogenic fungi Drechslera maydis and Drechslera sorghicola
inferredcites →https://doi.org/10.1073/pnas.97.26.14376openalex-snapshot
An alternative, nonapoptotic form of programmed cell death
inferredcites →https://doi.org/10.1080/00021369.1972.10860584openalex-snapshot
Production and Characterization of a New Fungal Metabolite, Cotylenol
inferredcites →https://doi.org/10.1080/14786419.2015.1022777openalex-snapshot
Biological activities of ophiobolin K and 6-epi-ophiobolin K produced by the endophytic fungusAspergillus calidoustus
inferredcites →https://doi.org/10.1080/14786419.2015.1062760openalex-snapshot
Anticancer activity of Ophiobolin A, isolated from the endophytic fungus Bipolaris setariae
inferredcites →https://doi.org/10.1080/14786419.2016.1253084openalex-snapshot
Influence of light on the biosynthesis of ophiobolin A by Bipolaris maydis
inferredcites →https://doi.org/10.1104/pp.118.3.965openalex-snapshot
Identification of the Binding and Inhibition Sites in the Calmodulin Molecule for Ophiobolin A by Site-Directed Mutagenesis
inferredcites →https://doi.org/10.1104/pp.77.2.303openalex-snapshot
Role of Calmodulin Inhibition in the Mode of Action of Ophiobolin A
inferredcites →https://doi.org/10.1126/science.aaf6742openalex-snapshot
Enantioselective synthesis of an ophiobolin sesterterpene via a programmed radical cascade
inferredcites →https://doi.org/10.1211/146080800128736312openalex-snapshot
Ophiobolin A, a Novel Apoptosis-inducing Agent from Fungus Strain f-7438
inferredcites →https://doi.org/10.1371/journal.pone.0167672openalex-snapshot
Ophiobolin A Induces Autophagy and Activates the Mitochondrial Pathway of Apoptosis in Human Melanoma Cells
inferredcites →https://doi.org/10.3109/01913123.2012.751949openalex-snapshot
Ultrastructural Patterns of the Activated Cell Death Programs in the Human Brain
inferredcites →https://doi.org/10.3390/md11114570openalex-snapshot
Ophiobolin-O Reverses Adriamycin Resistance via Cell Cycle Arrest and Apoptosis Sensitization in Adriamycin-Resistant Human Breast Carcinoma (MCF-7/ADR) Cells
inferredcites →https://doi.org/10.3390/md13010431openalex-snapshot
Ophiobolin O Isolated from Aspergillus ustus Induces G1 Arrest of MCF-7 Cells through Interaction with AKT/GSK3β/Cyclin D1 Signaling
inferredcites →https://doi.org/10.3390/md15070229openalex-snapshot
The Biological Activities of Sesterterpenoid-Type Ophiobolins
inferredcites →https://doi.org/10.3892/ijo.2013.1979openalex-snapshot
Ophiobolin A, a sesterterpenoid fungal phytotoxin, displays higher in vitro growth-inhibitory effects in mammalian than in plant cells and displays in vivo antitumor activity
inferredcites →https://doi.org/10.3892/ijo.2017.3858openalex-snapshot
Ophiobolin A, a sesterpenoid fungal phytotoxin, displays different mechanisms of cell death in mammalian cells depending upon the cancer cell origin
inferredcites →https://doi.org/10.7554/elife.14601openalex-snapshot
The anticancer natural product ophiobolin A induces cytotoxicity by covalent modification of phosphatidylethanolamine
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4818930openalex-extracted
Uplc-Q-Tof-Ms/Ms Analysis of Ophiobolins Sesterterpenoids to Mine New and Bioactive Analogues from Bipolaris Eleusines
inferred← citeshttps://doi.org/10.1002/9781119737582.ch9openalex-snapshot
Biological Control and Use of Bioherbicides
inferred← citeshttps://doi.org/10.1002/ange.201913150openalex-snapshot
Total Synthesis of (+)‐6‐epi‐Ophiobolin A
inferred← citeshttps://doi.org/10.1002/ange.202319306openalex-snapshot
Bioinspired Total Synthesis of Bipolarolides A and B
inferred← citeshttps://doi.org/10.1002/anie.201913150openalex-snapshot
Total Synthesis of (+)‐6‐epi‐Ophiobolin A
inferred← citeshttps://doi.org/10.1002/anie.202319306openalex-snapshot
Bioinspired Total Synthesis of Bipolarolides A and B
inferred← citeshttps://doi.org/10.1002/cbdv.202100976openalex-snapshot
Exploration of Potent Cytotoxic Molecules from Fungi in Recent Past to Discover Plausible Anticancer Scaffolds
inferred← citeshttps://doi.org/10.1002/ejoc.202100122openalex-snapshot
Lithium Hydroxide Assisted Endo‐Selective [4+4]‐Photocycloaddition of Pyran‐2‐ones
inferred← citeshttps://doi.org/10.1002/ptr.8354openalex-snapshot
A Marine‐Derived Small Molecule Inhibits Prostate Cancer Growth by Promoting Endoplasmic Reticulum Stress Induced Apoptosis and Autophagy
inferred← citeshttps://doi.org/10.1007/978-3-031-18587-8_13openalex-snapshot
Biochemistry of Secondary Metabolism of Fungi
inferred← citeshttps://doi.org/10.1007/978-981-99-5696-8_5openalex-snapshot
Endolichenic Fungi, an Emerging Source of Bioactive Compounds: A Pharmaceutical Perspective
inferred← citeshttps://doi.org/10.1007/s00253-019-10103-xopenalex-snapshot
Production of sesterterpene ophiobolin by a bifunctional terpene synthase in Escherichia coli
inferred← citeshttps://doi.org/10.1007/s11101-019-09624-0openalex-snapshot
Phytotoxins produced by pathogenic fungi of agrarian plants
inferred← citeshttps://doi.org/10.1016/b978-0-12-819092-0.00004-2openalex-snapshot
Terpene toxicity and oxidative stress
inferred← citeshttps://doi.org/10.1016/j.apsb.2023.08.025openalex-snapshot
Genomics-driven derivatization of the bioactive fungal sesterterpenoid variecolin: Creation of an unnatural analogue with improved anticancer properties
inferred← citeshttps://doi.org/10.1016/j.bcp.2026.118527openalex-snapshot
Marine-derived ophiobolin MHO7 targets voltage-dependent anion channel 2 and promotes its degradation in triple-negative breast cancer
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.114081openalex-snapshot
Design and synthesis of marine sesterterpene analogues as novel estrogen receptor α degraders for breast cancer treatment
inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114313openalex-snapshot
Synthesis and structure-activity relationship study of a potent MHO7 analogue as potential anti-triple negative breast cancer agent
inferred← citeshttps://doi.org/10.1016/j.hermed.2025.100992openalex-snapshot
Evaluation of milk thistle (Silybum marianum) phytochemicals as curative agents of retinoblastoma using in-silico approach
inferred← citeshttps://doi.org/10.1016/j.jspr.2026.103018openalex-snapshot
Insights into the host-pathogen interaction of emerging disease, seed discoloration in rice: Losses, pathogenomics, and management strategies
inferred← citeshttps://doi.org/10.1016/j.phrs.2020.104953openalex-snapshot
Erinacine A and related cyathane diterpenoids: Molecular diversity and mechanisms underlying their neuroprotection and anticancer activities
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113352openalex-snapshot
Cyophiobiolins A-D, ophiobolin sestertepenoids from Cytospora rhizophorae
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114267openalex-snapshot
UPLC-Q-TOF-MS/MS analysis of ophiobolins sesterterpenoids and bioactive analogs from Bipolaris eleusines
inferred← citeshttps://doi.org/10.1016/j.phytochem.2026.114802openalex-snapshot
1H NMR-guided isolation of ophiobolins from Bipolaris maydis and their bioactivities
inferred← citeshttps://doi.org/10.1016/j.tetlet.2021.153608openalex-snapshot
Synthesis of the eight-membered carbocycle of brachialactone by intramolecular Mizoroki-Heck reaction
inferred← citeshttps://doi.org/10.1021/acs.accounts.0c00055openalex-snapshot
Syntheses of Complex Terpenes from Simple Polyprenyl Precursors
inferred← citeshttps://doi.org/10.1021/acs.chemrev.0c00045openalex-snapshot
Recent Advances in the Total Synthesis of Natural Products Containing Eight-Membered Carbocycles (2009–2019)
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c03352openalex-snapshot
LC–MS/MS-Guided Molecular Networking for Targeted Discovery of Undescribed and Bioactive Ophiobolins from Bipolaris eleusines
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c00836openalex-snapshot
Drophiobiolins A and B, Bioactive Ophiobolan Sestertepenoids Produced byDreschslera gigantea
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.5c01414openalex-snapshot
Gigobolins A–C, New Ophiobolins with Anticancer Activity from the Phytopathogenic Fungus Drechslera gigantea
inferred← citeshttps://doi.org/10.1021/acs.orglett.0c02938openalex-snapshot
Pharmacophore-Directed Retrosynthesis Applied to Ophiobolin A: Simplified Bicyclic Derivatives Displaying Anticancer Activity
inferred← citeshttps://doi.org/10.1021/acs.orglett.2c02272openalex-snapshot
A Stereoselective Photoinduced Cycloisomerization Inspired by Ophiobolin A
inferred← citeshttps://doi.org/10.1021/acschembio.4c00064openalex-snapshot
Ophiobolin A Covalently Targets Mitochondrial Complex IV Leading to Metabolic Collapse in Cancer Cells
inferred← citeshttps://doi.org/10.1021/jacs.2c04633openalex-snapshot
Asymmetric Total Syntheses of Hypoestin A, Albolic Acid, and Ceroplastol II
inferred← citeshttps://doi.org/10.1021/jacs.2c12750openalex-snapshot
Organocatalytic Enantioselective Thermal [4 + 4] Cycloadditions
inferred← citeshttps://doi.org/10.1038/s41598-021-89923-9openalex-snapshot
Epithelial-mesenchymal transition sensitizes breast cancer cells to cell death via the fungus-derived sesterterpenoid ophiobolin A
inferred← citeshttps://doi.org/10.1039/d0np00048eopenalex-snapshot
Bridging the gap between natural product synthesis and drug discovery
inferred← citeshttps://doi.org/10.1039/d0np00070aopenalex-snapshot
Sesterterpenoids: chemistry, biology, and biosynthesis
inferred← citeshttps://doi.org/10.1039/d3np00002hopenalex-snapshot
Therapeutic vulnerabilities of cancer stem cells and effects of natural products
inferred← citeshttps://doi.org/10.1039/d3np00035dopenalex-snapshot
The incredible story of ophiobolin A and sphaeropsidin A: two fungal terpenes from wilt-inducing phytotoxins to promising anticancer compounds
inferred← citeshttps://doi.org/10.1039/d4np00041bopenalex-snapshot
Sesterterpenoids: sources, structural diversity, biological activity, and data management
inferred← citeshttps://doi.org/10.1080/14786419.2020.1860975openalex-snapshot
Augmented phytotoxic effect of nanoencapsulated ophiobolin A
inferred← citeshttps://doi.org/10.1101/2025.04.08.647828openalex-snapshot
Ophiobolin A selectively alters mitochondria, metabolism and redox biology in breast cancer and mammary epithelial cells which have undergone epithelial to mesenchymal transition
inferred← citeshttps://doi.org/10.1101/2025.04.08.647841openalex-snapshot
PANoptosis, a combination of inflammatory cell death mechanisms, induced by Ophiobolin A in breast cancer cell lines
inferred← citeshttps://doi.org/10.1158/1535-7163.mct-21-0175openalex-snapshot
Development of a High-throughput NanoBRET Screening Platform to Identify Modulators of the RAS/RAF Interaction
inferred← citeshttps://doi.org/10.1186/s12935-025-04135-9openalex-snapshot
Ophiobolin A impacts mitochondrial redox biology in an epithelial-mesenchymal transition (EMT)-specific manner
inferred← citeshttps://doi.org/10.2174/1389557520666200807133659openalex-snapshot
Modulation of Calcium Signaling in Glioblastoma Multiforme: A Therapeutic Promise for Natural Products
inferred← citeshttps://doi.org/10.33774/chemrxiv-2021-x171copenalex-snapshot
Heterologous Biosynthesis and Genomics-Driven Derivatization of Fungal Bioactive Sesterterpenoid Variecolin
inferred← citeshttps://doi.org/10.3390/biom11020240openalex-snapshot
Arabidopsis Defense against the Pathogenic Fungus Drechslera gigantea Is Dependent on the Integrity of the Unfolded Protein Response
inferred← citeshttps://doi.org/10.3390/biom11091393openalex-snapshot
The Surprising Story of Fusicoccin: A Wilt-Inducing Phytotoxin, a Tool in Plant Physiology and a 14-3-3-Targeted Drug
inferred← citeshttps://doi.org/10.3390/ijms222011256openalex-snapshot
Polygodial and Ophiobolin A Analogues for Covalent Crosslinking of Anticancer Targets
inferred← citeshttps://doi.org/10.3390/ijms241411867openalex-snapshot
The Use of Photodynamic Therapy for Head, Neck, and Brain Diseases
inferred← citeshttps://doi.org/10.3390/ijms27020618openalex-snapshot
Gasdermin D Cleavage and Cytokine Release, Indicative of Pyroptotic Cell Death, Induced by Ophiobolin A in Breast Cancer Cell Lines
inferred← citeshttps://doi.org/10.3390/microorganisms11040843openalex-snapshot
Specialized Metabolites Produced by Phytotopatogen Fungi to Control Weeds and Parasite Plants
inferred← citeshttps://doi.org/10.3390/molecules31071206openalex-snapshot
From Phytotoxin to Cell-Death Probe: Ophiobolin A and Related Sesterterpenoids in Membrane Stress and Non-Apoptotic Cell Death
inferred← citeshttps://doi.org/10.3390/toxins13040261openalex-snapshot
Phytotoxic Secondary Metabolites from Fungi
inferred← citeshttps://doi.org/10.3390/toxins14080517openalex-snapshot
In Vitro Effects of Fungal Phytotoxins on Cancer Cell Viability: First Insight into Structure Activity Relationship of a Potent Metabolite of Cochliobolus australiensis Radicinin
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