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Biophysical Properties of Novel 1-Deoxy-(Dihydro)ceramides Occurring in Mammalian Cells

https://doi.org/10.1016/j.bpj.2014.10.010

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Ceramide acyl chain length markedly influences miscibility with palmitoyl sphingomyelin in bilayer membranes

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Spisulosine (ES-285) given as a weekly three-hour intravenous infusion: results of a phase I dose-escalating study in patients with advanced solid malignancies

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The marine sphingolipid-derived compound ES 285 triggers an atypical cell death pathway

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Phase I dose-escalating study of ES-285 given as a three-hour intravenous infusion every three weeks in patients with advanced malignant solid tumors

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Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory and Autonomic Neuropathy Type I

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Biophysics of sphingolipids I. Membrane properties of sphingosine, ceramides and other simple sphingolipids

inferredcites →https://doi.org/10.1016/j.bbamem.2008.09.002openalex-snapshot

Effects of ceramide and other simple sphingolipids on membrane lateral structure

inferredcites →https://doi.org/10.1016/j.bbamem.2009.02.019openalex-snapshot

Thermotropic behavior and lateral distribution of very long chain sphingolipids

inferredcites →https://doi.org/10.1016/j.bbamem.2011.07.023openalex-snapshot

Effect of ceramide structure on membrane biophysical properties: The role of acyl chain length and unsaturation

inferredcites →https://doi.org/10.1016/j.bbamem.2013.10.010openalex-snapshot

Lipid bilayers containing sphingomyelins and ceramides of varying N-acyl lengths: A glimpse into sphingolipid complexity

inferredcites →https://doi.org/10.1016/j.bpj.2009.08.040openalex-snapshot

Coexistence of Immiscible Mixtures of Palmitoylsphingomyelin and Palmitoylceramide in Monolayers and Bilayers

inferredcites →https://doi.org/10.1016/j.bpj.2013.11.1687openalex-snapshot

Lipid Bilayers Containing Sphingomyelins and Ceramides of Varying N-Acyl Lengths: a Glimpse into Sphingolipid Complexity

inferredcites →https://doi.org/10.1016/j.chemphyslip.2010.04.008openalex-snapshot

Phase state and surface topography of palmitoyl-ceramide monolayers

inferredcites →https://doi.org/10.1016/j.ejphar.2008.02.011openalex-snapshot

Spisulosine (ES-285) induces prostate tumor PC-3 and LNCaP cell death by de novo synthesis of ceramide and PKCζ activation

inferredcites →https://doi.org/10.1016/j.plipres.2011.11.001openalex-snapshot

Chain length-specific properties of ceramides

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The interfacial elastic packing interactions of galactosylceramides, sphingomyelins, and phosphatidylcholines

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Structural and thermotropic properties of synthetic C16:0 (palmitoyl) ceramide: effect of hydration.

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Sphingolipid and Glycosphingolipid Metabolic Pathways in the Era of Sphingolipidomics

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Ceramide N-Acyl Chain Length: A Determinant of Bidimensional Transitions, Condensed Domain Morphology, and Interfacial Thickness

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Kdo2-Lipid A, a TLR4-specific Agonist, Induces de Novo Sphingolipid Biosynthesis in RAW264.7 Macrophages, Which Is Essential for Induction of Autophagy

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A Mouse Macrophage Lipidome

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Ceramide Synthase Inhibition by Fumonisin B1 Causes Accumulation of 1-Deoxysphinganine

inferredcites →https://doi.org/10.1074/jbc.r111.254359openalex-snapshot

Many Ceramides

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Ceramide-platform formation and -induced biophysical changes in a fluid phospholipid membrane

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Phase I safety, pharmacokinetic, and pharmacogenomic trial of ES-285, a novel marine cytotoxic agent, administered to adult patients with advanced solid tumors

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Deoxysphingolipids, Novel Biomarkers for Type 2 Diabetes, Are Cytotoxic for Insulin-Producing Cells

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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(1-Deoxy)Ceramides in Bilayers Containing Sphingomyelin and Cholesterol

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Lipidomics in Cell Biology

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Demyelination in hereditary sensory neuropathy type‐1C

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Sphingoid Base Diversity

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1-deoxysphingolipids dysregulate membrane properties and cargo trafficking in the early secretory pathway

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Cholesterol interactions with ceramide and sphingomyelin

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The puzzle of sphingolipids and cholesterol under the atomic force microscope: bilayer thicknesses and breakthrough forces

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(1-Deoxy)ceramides in bilayers containing sphingomyelin and cholesterol

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