On the public citation graph
Hereditary sensory neuropathy type 1-associated deoxysphingolipids cause neurotoxicity, acute calcium handling abnormalities and mitochondrial dysfunction in vitro
0 signed · 112 inferred · view as graph
Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.
Is this your work? Sign in with ORCID and put your name on the
claims that are yours.
Reference health. See whether every reference in this work resolves to a
known work and none has been retracted — and get a dated CiteStamped
badge you can embed.
What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/2211-5463.12038openalex-snapshot
Adaptive response to l ‐serine deficiency is mediated by p38 MAPK activation via 1‐deoxysphinganine in normal fibroblasts
inferredcites →https://doi.org/10.1002/humu.21481openalex-snapshot
Characterization of two mutations in the SPTLC1 subunit of serine palmitoyltransferase associated with hereditary sensory and autonomic neuropathy type I
inferredcites →https://doi.org/10.1007/bf00762735openalex-snapshot
Recent progress on regulation of the mitochondrial permeability transition pore; a cyclosporin-sensitive pore in the inner mitochondrial membrane
inferredcites →https://doi.org/10.1007/bf00769537openalex-snapshot
The mitochondrial megachannel is the permeability transition pore
inferredcites →https://doi.org/10.1007/s00125-011-2384-1openalex-snapshot
Plasma deoxysphingolipids: a novel class of biomarkers for the metabolic syndrome?
inferredcites →https://doi.org/10.1007/s00415-011-6397-yopenalex-snapshot
Frequency of mutations in the genes associated with hereditary sensory and autonomic neuropathy in a UK cohort
inferredcites →https://doi.org/10.1007/s10495-006-0573-zopenalex-snapshot
The marine sphingolipid-derived compound ES 285 triggers an atypical cell death pathway
inferredcites →https://doi.org/10.1007/s12017-015-8379-1openalex-snapshot
The Variant p.(Arg183Trp) in SPTLC2 Causes Late-Onset Hereditary Sensory Neuropathy
inferredcites →https://doi.org/10.1007/s12154-014-0125-xopenalex-snapshot
Mitochondrial protein alterations in a familial peripheral neuropathy caused by the V144D amino acid mutation in the sphingolipid protein, SPTLC1
inferredcites →https://doi.org/10.1016/0925-4439(95)00015-vopenalex-snapshot
Calcium ion-dependent signalling and mitochondrial dysfunction: mitochondrial calcium uptake during hormonal stimulation in intact liver cells and its implication for the mitochondrial permeability transition
inferredcites →https://doi.org/10.1016/b978-0-444-52902-2.00050-3openalex-snapshot
Hereditary sensory and autonomic neuropathies
inferredcites →https://doi.org/10.1016/j.ajhg.2010.09.010openalex-snapshot
Mutations in the SPTLC2 Subunit of Serine Palmitoyltransferase Cause Hereditary Sensory and Autonomic Neuropathy Type I
inferredcites →https://doi.org/10.1016/j.bbamcr.2016.11.028openalex-snapshot
The functions of store-operated calcium channels
inferredcites →https://doi.org/10.1016/j.bbamem.2006.05.027openalex-snapshot
Sphingolipid metabolism diseases
inferredcites →https://doi.org/10.1016/j.bpj.2014.10.010openalex-snapshot
Biophysical Properties of Novel 1-Deoxy-(Dihydro)ceramides Occurring in Mammalian Cells
inferredcites →https://doi.org/10.1016/j.ejmg.2013.02.002openalex-snapshot
Mutations at Ser331 in the HSN type I gene SPTLC1 are associated with a distinct syndromic phenotype
inferredcites →https://doi.org/10.1016/j.nbd.2013.03.010openalex-snapshot
Silencing of the Charcot–Marie–Tooth disease-associated gene GDAP1 induces abnormal mitochondrial distribution and affects Ca2+ homeostasis by reducing store-operated Ca2+ entry
inferredcites →https://doi.org/10.1016/j.neuint.2007.02.008openalex-snapshot
The mitochondrial permeability transition in neurologic disease
inferredcites →https://doi.org/10.1016/j.neuropharm.2016.03.033openalex-snapshot
1-Deoxysphingolipid-induced neurotoxicity involves N-methyl-d-aspartate receptor signaling
inferredcites →https://doi.org/10.1016/j.tcb.2008.12.002openalex-snapshot
MAM: more than just a housekeeper
inferredcites →https://doi.org/10.1016/s0006-3495(83)84449-xopenalex-snapshot
The molecular mechanism of action of the proton ionophore FCCP (carbonylcyanide p-trifluoromethoxyphenylhydrazone)
inferredcites →https://doi.org/10.1016/s0022-510x(00)00414-7openalex-snapshot
Ca2+-permeable AMPA receptors and selective vulnerability of motor neurons
inferredcites →https://doi.org/10.1016/s0143-4160(02)00203-8openalex-snapshot
Actions of ionomycin, 4-BrA23187 and a novel electrogenic Ca2+ ionophore on mitochondria in intact cells
inferredcites →https://doi.org/10.1016/s0304-3835(99)00428-0openalex-snapshot
The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers
inferredcites →https://doi.org/10.1016/s1388-1981(03)00059-3openalex-snapshot
Serine palmitoyltransferase, a key enzyme of sphingolipid metabolism
inferredcites →https://doi.org/10.1016/s1474-4422(12)70065-0openalex-snapshot
Diabetic neuropathy: clinical manifestations and current treatments
inferredcites →https://doi.org/10.1038/17135openalex-snapshot
Molecular characterization of mitochondrial apoptosis-inducing factor
inferredcites →https://doi.org/10.1038/35040009openalex-snapshot
Apoptosis in neurodegenerative disorders
inferredcites →https://doi.org/10.1038/85879openalex-snapshot
Mutations in SPTLC1, encoding serine palmitoyltransferase, long chain base subunit-1, cause hereditary sensory neuropathy type I
inferredcites →https://doi.org/10.1038/nchembio.392openalex-snapshot
An update on sphingosine-1-phosphate and other sphingolipid mediators
inferredcites →https://doi.org/10.1038/ng0596-101openalex-snapshot
The gene for hereditary sensory neuropathy type I (HSN–I) maps to chromosome 9q22.1–q22.3
inferredcites →https://doi.org/10.1038/nrneurol.2011.227openalex-snapshot
Mechanisms of disease in hereditary sensory and autonomic neuropathies
inferredcites →https://doi.org/10.1038/srep42993openalex-snapshot
CMT-linked loss-of-function mutations in GDAP1 impair store-operated Ca2+ entry-stimulated respiration
inferredcites →https://doi.org/10.1042/bst0390789openalex-snapshot
A diversity of SERCA Ca2+ pump inhibitors
inferredcites →https://doi.org/10.1074/jbc.272.36.22432openalex-snapshot
Characterization of Ceramide Synthesis
inferredcites →https://doi.org/10.1074/jbc.272.51.32108openalex-snapshot
A Mammalian Homolog of the Yeast LCB1 Encodes a Component of Serine Palmitoyltransferase, the Enzyme Catalyzing the First Step in Sphingolipid Synthesis
inferredcites →https://doi.org/10.1074/jbc.m109.092973openalex-snapshot
Hereditary Sensory Neuropathy Type 1 Is Caused by the Accumulation of Two Neurotoxic Sphingolipids
inferredcites →https://doi.org/10.1074/jbc.m110.122259openalex-snapshot
A Disease-causing Mutation in the Active Site of Serine Palmitoyltransferase Causes Catalytic Promiscuity
inferredcites →https://doi.org/10.1074/jbc.m114.603860openalex-snapshot
l-Serine Deficiency Elicits Intracellular Accumulation of Cytotoxic Deoxysphingolipids and Lipid Body Formation
inferredcites →https://doi.org/10.1074/jbc.m212971200openalex-snapshot
Mitochondria Efficiently Buffer Subplasmalemmal Ca2+Elevation during Agonist Stimulation
inferredcites →https://doi.org/10.1074/jbc.m808798200openalex-snapshot
Ceramide Synthase Inhibition by Fumonisin B1 Causes Accumulation of 1-Deoxysphinganine
inferredcites →https://doi.org/10.1074/jbc.r115.658823openalex-snapshot
1-Deoxysphingolipids Encountered Exogenously and Made de Novo: Dangerous Mysteries inside an Enigma
inferredcites →https://doi.org/10.1083/jcb.200604016openalex-snapshot
Structural and functional features and significance of the physical linkage between ER and mitochondria
inferredcites →https://doi.org/10.1084/jem.189.2.381openalex-snapshot
Mitochondrial Release of Caspase-2 and -9 during the Apoptotic Process
inferredcites →https://doi.org/10.1089/dna.2013.2182openalex-snapshot
Mutations in the SPTLC1 Protein Cause Mitochondrial Structural Abnormalities and Endoplasmic Reticulum Stress in Lymphoblasts
inferredcites →https://doi.org/10.1093/brain/awh712openalex-snapshot
Clinical, pathological and genetic characterization of hereditary sensory and autonomic neuropathy type 1 (HSAN I)
inferredcites →https://doi.org/10.1096/fasebj.9.2.7781924openalex-snapshot
Calcium‐mediated cell injury and cell death
inferredcites →https://doi.org/10.1097/00019052-200410000-00007openalex-snapshot
Hereditary sensory neuropathies
inferredcites →https://doi.org/10.1111/j.1432-1033.1997.00239.xopenalex-snapshot
Human and Murine Serine‐Palmitoyl‐CoA Transferase
inferredcites →https://doi.org/10.1128/jb.173.14.4325-4332.1991openalex-snapshot
Cloning and characterization of LCB1, a Saccharomyces gene required for biosynthesis of the long-chain base component of sphingolipids
inferredcites →https://doi.org/10.1152/physrev.00057.2003openalex-snapshot
Store-Operated Calcium Channels
inferredcites →https://doi.org/10.1172/jci57549openalex-snapshot
Oral l-serine supplementation reduces production of neurotoxic deoxysphingolipids in mice and humans with hereditary sensory autonomic neuropathy type 1
inferredcites →https://doi.org/10.1186/1476-511x-9-84openalex-snapshot
Deoxysphingoid bases as plasma markers in Diabetes mellitus
inferredcites →https://doi.org/10.1194/jlr.m067033openalex-snapshot
Elucidating the chemical structure of native 1-deoxysphingosine
inferredcites →https://doi.org/10.1194/jlr.m068676openalex-snapshot
Localization of 1-deoxysphingolipids to mitochondria induces mitochondrial dysfunction
inferredcites →https://doi.org/10.1194/jlr.m072421openalex-snapshot
Cytotoxic 1-deoxysphingolipids are metabolized by a cytochrome P450-dependent pathway
inferredcites →https://doi.org/10.1212/wnl.0b013e318295d789openalex-snapshot
Hereditary sensory and autonomic neuropathy type 1 (HSANI) caused by a novel mutation in SPTLC2
inferredcites →https://doi.org/10.1371/journal.pgen.1005115openalex-snapshot
Lack of GDAP1 Induces Neuronal Calcium and Mitochondrial Defects in a Knockout Mouse Model of Charcot-Marie-Tooth Neuropathy
inferredcites →https://doi.org/10.2337/db13-1042openalex-snapshot
Deoxysphingolipids, Novel Biomarkers for Type 2 Diabetes, Are Cytotoxic for Insulin-Producing Cells
inferredcites →https://doi.org/10.2337/db14-1325openalex-snapshot
Lowering Plasma 1-Deoxysphingolipids Improves Neuropathy in Diabetic Rats
inferredcites →https://doi.org/10.55782/ane-2015-2023openalex-snapshot
Molecular pathogenesis, experimental therapy and genetic counseling in hereditary sensory neuropathies
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4794969openalex-extracted
(1-Deoxy)Ceramides in Bilayers Containing Sphingomyelin and Cholesterol
inferred← citeshttps://doi.org/10.1001/jamaneurol.2021.2598openalex-snapshot
Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis
inferred← citeshttps://doi.org/10.1002/glia.70071openalex-snapshot
The Influence of Schwann Cell Metabolism and Dysfunction on Axon Maintenance
inferred← citeshttps://doi.org/10.1002/jimd.12745openalex-snapshot
Human genetic defects of sphingolipid synthesis
inferred← citeshttps://doi.org/10.1002/mc.70023openalex-snapshot
The Contradictory Effects of SPTLC1 on Clear Cell Renal Carcinoma Sensitivity to Sunitinib Mediated by Androgen Receptor
inferred← citeshttps://doi.org/10.1007/s00415-022-11164-1openalex-snapshot
Neurological update: hereditary neuropathies
inferred← citeshttps://doi.org/10.1007/s12017-021-08646-2openalex-snapshot
Sphingolipids as Regulators of Neuro-Inflammation and NADPH Oxidase 2
inferred← citeshttps://doi.org/10.1007/s12017-021-08698-4openalex-snapshot
Deoxysphingolipids Upregulate MMP-1, Downregulate TIMP-1, and Induce Cytotoxicity in Human Schwann Cells
inferred← citeshttps://doi.org/10.1016/j.atherosclerosis.2024.119091openalex-snapshot
Sphingoid Base Diversity
inferred← citeshttps://doi.org/10.1016/j.cellsig.2020.109890openalex-snapshot
The noncanonical chronicles: Emerging roles of sphingolipid structural variants
inferred← citeshttps://doi.org/10.1016/j.celrep.2026.118089openalex-snapshot
Deoxysphingolipids activate cGAS-STING and enhance antitumor immunity
inferred← citeshttps://doi.org/10.1016/j.colsurfb.2024.114155openalex-snapshot
(1-Deoxy)ceramides in bilayers containing sphingomyelin and cholesterol
inferred← citeshttps://doi.org/10.1016/j.coph.2021.08.011openalex-snapshot
Dietary serine supplementation: Friend or foe?
inferred← citeshttps://doi.org/10.1016/j.cpsurg.2026.102140openalex-snapshot
Identification of biomarkers for FANCI and mitochondrial dysfunction in focal cortical dysplasia
inferred← citeshttps://doi.org/10.1016/j.foodres.2021.110566openalex-snapshot
Sphingolipids in foodstuff: Compositions, distribution, digestion, metabolism and health effects – A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.jbc.2023.104684openalex-snapshot
Structural insights into the substrate recognition of serine palmitoyltransferase from Sphingobacterium multivorum
inferred← citeshttps://doi.org/10.1016/j.jbc.2026.113258openalex-snapshot
The riddle of sphingolipid structure-function relationship in the nervous system
inferred← citeshttps://doi.org/10.1016/j.jbior.2018.10.004openalex-snapshot
Sphingoid bases and their involvement in neurodegenerative diseases
inferred← citeshttps://doi.org/10.1016/j.jdiacomp.2021.107852openalex-snapshot
Altered plasma serine and 1-deoxydihydroceramide profiles are associated with diabetic neuropathy in type 2 diabetes and obesity
inferred← citeshttps://doi.org/10.1016/j.jlr.2021.100122openalex-snapshot
Metabolism of HSAN1- and T2DM-associated 1-deoxy-sphingolipids inhibits the migration of fibroblasts
inferred← citeshttps://doi.org/10.1016/j.jlr.2026.101141openalex-snapshot
Mechanisms of deoxysphinganine cytotoxicity in lymphoma cells
inferred← citeshttps://doi.org/10.1016/j.neuron.2025.04.006openalex-snapshot
Lipid metabolism alterations in peripheral neuropathies
inferred← citeshttps://doi.org/10.1016/j.plipres.2019.100988openalex-snapshot
Mammalian sphingoid bases: Biophysical, physiological and pathological properties
inferred← citeshttps://doi.org/10.1016/j.plipres.2019.100995openalex-snapshot
WITHDRAWN: Mammalian sphingoid bases: Biophysical, physiological and pathological properties
inferred← citeshttps://doi.org/10.1016/j.prostaglandins.2023.106769openalex-snapshot
A novel HSPB1S139F mouse model of Charcot-Marie-Tooth Disease
inferred← citeshttps://doi.org/10.1016/j.tem.2023.03.001openalex-snapshot
Serine signaling governs metabolic homeostasis and health
inferred← citeshttps://doi.org/10.1016/j.xcrm.2021.100345openalex-snapshot
An iPSC model of hereditary sensory neuropathy-1 reveals L-serine-responsive deficits in neuronal ganglioside composition and axoglial interactions
inferred← citeshttps://doi.org/10.1038/s41467-023-39775-wopenalex-snapshot
Imbalanced unfolded protein response signaling contributes to 1-deoxysphingolipid retinal toxicity
inferred← citeshttps://doi.org/10.1038/s41467-025-66687-8openalex-snapshot
Very long-chain fatty acids drive 1-deoxySphingolipid toxicity
inferred← citeshttps://doi.org/10.1038/s41572-022-00365-7openalex-snapshot
Genetic pain loss disorders
inferred← citeshttps://doi.org/10.1056/nejmoa1815111openalex-snapshot
Serine and Lipid Metabolism in Macular Disease and Peripheral Neuropathy
inferred← citeshttps://doi.org/10.1080/15548627.2020.1804677openalex-snapshot
1-Deoxysphingolipids cause autophagosome and lysosome accumulation and trigger NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1089/dna.2021.0816openalex-snapshot
Calcium-Mediated Calpain Activation and Microtubule Dissociation in Cell Model of Hereditary Sensory Neuropathy Type-1 Expressing V144D SPTLC1 Mutation
inferred← citeshttps://doi.org/10.1091/mbc.e19-07-0364openalex-snapshot
Cytotoxicity of 1-deoxysphingolipid unraveled by genome-wide genetic screens and lipidomics in Saccharomyces cerevisiae
inferred← citeshttps://doi.org/10.1101/2021.01.21.427595openalex-snapshot
1-Deoxysphingolipids Tempt Autophagy Resulting in Lysosomal Lipid Substrate Accumulation: Tracing the Impact of 1-Deoxysphingolipids on Ultra-Structural Level using a Novel Click-Chemistry Detection
inferred← citeshttps://doi.org/10.1101/2024.10.16.618749openalex-snapshot
Deoxysphingolipids activate cGAS-STING1 and enhance antitumor immunity
inferred← citeshttps://doi.org/10.1101/2025.05.13.653734openalex-snapshot
Very long chain fatty acids drive 1-deoxy-Sphingolipid toxicity
inferred← citeshttps://doi.org/10.1101/770339openalex-snapshot
Mutations in the SPTLC1 gene are a cause of juvenile amyotrophic lateral sclerosis that may be amenable to serine supplementation
inferred← citeshttps://doi.org/10.1111/ane.13650openalex-snapshot
Blood biomarkers of peripheral neuropathy
inferred← citeshttps://doi.org/10.1111/jnc.14985openalex-snapshot
Role of 1‐Deoxysphingolipids in docetaxel neurotoxicity
inferred← citeshttps://doi.org/10.1111/jns.12508openalex-snapshot
Description of a patient cohort with Hereditary Sensory Neuropathy type 1 without retinal disease Macular Telangiectasia type 2 ‐ implications for retinal screening in HSN1
inferred← citeshttps://doi.org/10.1136/jnnp-2020-323016openalex-snapshot
Humans: the ultimate animal models
inferred← citeshttps://doi.org/10.1186/s13024-026-00932-6openalex-snapshot
Lipid alterations in hereditary peripheral neuropathies: common mechanisms in disease heterogeneity?
inferred← citeshttps://doi.org/10.1212/nxg.0000000000000365openalex-snapshot
Deoxysphingolipids as candidate biomarkers for a novel SPTLC1 mutation associated with HSAN-I
inferred← citeshttps://doi.org/10.2337/db22-1018openalex-snapshot
Deoxysphingolipids: Atypical Skeletal Muscle Lipids Related to Insulin Resistance in Humans That Decrease Insulin Sensitivity In Vitro
inferred← citeshttps://doi.org/10.26444/aaem/134151openalex-snapshot
Genetic aspects of pain and its variability in the human population
inferred← citeshttps://doi.org/10.26508/lsa.202101278openalex-snapshot
Serine palmitoyltransferase assembles at ER–mitochondria contact sites
inferred← citeshttps://doi.org/10.3389/fendo.2021.772925openalex-snapshot
1-Deoxysphingolipids, Early Predictors of Type 2 Diabetes, Compromise the Functionality of Skeletal Myoblasts
inferred← citeshttps://doi.org/10.3390/biom13010168openalex-snapshot
The Dark Side of Sphingolipids: Searching for Potential Cardiovascular Biomarkers
inferred← citeshttps://doi.org/10.3390/dna6030040openalex-snapshot
Sphingolipid Regulation of Genome Stability: Stress Signaling, Chromatin Control, and Organelle Dysfunction
inferred← citeshttps://doi.org/10.3390/ijms20133304openalex-snapshot
The Link between Gaucher Disease and Parkinson’s Disease Sheds Light on Old and Novel Disorders of Sphingolipid Metabolism
Editorial review for independent work. ICSAC — the Institute for Complexity
Science and Advanced Computing — runs a structured editorial panel for researchers
publishing outside journals, and publishes on CiteStamp rails. Submission is free
and goes through ORCID: icsacinstitute.org/submit.