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Interleukin-1β Maturation Triggers Its Relocation to the Plasma Membrane for Gasdermin-D-Dependent and -Independent Secretion

https://doi.org/10.1016/j.celrep.2018.07.027

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1007/978-1-61779-527-5_15openalex-snapshot

Measuring the Inflammasome

inferredcites →https://doi.org/10.1016/j.cell.2010.01.040openalex-snapshot

The Inflammasomes

inferredcites →https://doi.org/10.1016/j.cell.2016.05.076openalex-snapshot

Hexokinase Is an Innate Immune Receptor for the Detection of Bacterial Peptidoglycan

inferredcites →https://doi.org/10.1016/j.celrep.2014.06.028openalex-snapshot

The Neutrophil NLRC4 Inflammasome Selectively Promotes IL-1β Maturation without Pyroptosis during Acute Salmonella Challenge

inferredcites →https://doi.org/10.1016/j.celrep.2014.07.012openalex-snapshot

Single-Cell Imaging of Caspase-1 Dynamics Reveals an All-or-None Inflammasome Signaling Response

inferredcites →https://doi.org/10.1016/j.celrep.2015.05.003openalex-snapshot

Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis

inferredcites →https://doi.org/10.1016/j.celrep.2017.06.073openalex-snapshot

XIAP Loss Triggers RIPK3- and Caspase-8-Driven IL-1β Activation and Cell Death as a Consequence of TLR-MyD88-Induced cIAP1-TRAF2 Degradation

inferredcites →https://doi.org/10.1016/j.chembiol.2017.03.009openalex-snapshot

Pyroptosis and Apoptosis Pathways Engage in Bidirectional Crosstalk in Monocytes and Macrophages

inferredcites →https://doi.org/10.1016/j.cyto.2015.03.022openalex-snapshot

Mechanisms of unconventional secretion of IL-1 family cytokines

inferredcites →https://doi.org/10.1016/j.imbio.2012.07.020openalex-snapshot

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

inferredcites →https://doi.org/10.1016/j.immuni.2012.09.015openalex-snapshot

Caspase-8 Blocks Kinase RIPK3-Mediated Activation of the NLRP3 Inflammasome

inferredcites →https://doi.org/10.1016/j.immuni.2016.01.012openalex-snapshot

Human Monocytes Engage an Alternative Inflammasome Pathway

inferredcites →https://doi.org/10.1016/j.immuni.2017.06.001openalex-snapshot

MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation

inferredcites →https://doi.org/10.1016/j.immuni.2017.11.013openalex-snapshot

The Pore-Forming Protein Gasdermin D Regulates Interleukin-1 Secretion from Living Macrophages

inferredcites →https://doi.org/10.1038/cdd.2015.176openalex-snapshot

Inflammasome-dependent IL-1β release depends upon membrane permeabilisation

inferredcites →https://doi.org/10.1038/cdd.2016.69openalex-snapshot

Cell death is not essential for caspase-1-mediated interleukin-1β activation and secretion

inferredcites →https://doi.org/10.1038/cr.2015.139openalex-snapshot

Gasdermin D is an executor of pyroptosis and required for interleukin-1β secretion

inferredcites →https://doi.org/10.1038/emboj.2011.398openalex-snapshot

Autophagy‐based unconventional secretory pathway for extracellular delivery of IL‐1β

inferredcites →https://doi.org/10.1038/nature15514openalex-snapshot

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

inferredcites →https://doi.org/10.1038/nature15541openalex-snapshot

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

inferredcites →https://doi.org/10.1038/nature18590openalex-snapshot

Pore-forming activity and structural autoinhibition of the gasdermin family

inferredcites →https://doi.org/10.1038/nature18629openalex-snapshot

Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores

inferredcites →https://doi.org/10.1038/ncomms9761openalex-snapshot

Human caspase-4 and caspase-5 regulate the one-step non-canonical inflammasome activation in monocytes

inferredcites →https://doi.org/10.1038/s41598-017-07081-3openalex-snapshot

Salmonella typhimurium-induced IL-1 release from primary human monocytes requires NLRP3 and can occur in the absence of pyroptosis

inferredcites →https://doi.org/10.1038/srep04736openalex-snapshot

Real-time single-cell imaging of protein secretion

inferredcites →https://doi.org/10.1073/pnas.1110156109openalex-snapshot

Conservation and divergence in Toll-like receptor 4-regulated gene expression in primary human versus mouse macrophages

inferredcites →https://doi.org/10.1073/pnas.1607769113openalex-snapshot

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

inferredcites →https://doi.org/10.1073/pnas.1613305114openalex-snapshot

Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner

inferredcites →https://doi.org/10.1084/jem.20172222openalex-snapshot

Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity

inferredcites →https://doi.org/10.1111/j.1462-5822.2006.00751.xopenalex-snapshot

Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages

inferredcites →https://doi.org/10.1111/tra.12415openalex-snapshot

Distinct Roles for APPL1 and APPL2 in Regulating Toll‐like Receptor 4 Signaling in Macrophages

inferredcites →https://doi.org/10.1124/mol.66.4.openalex-snapshot

Interleukin 2 (IL-2) variants engineered for increased IL-2 receptor alpha-subunit affinity exhibit increased potency arising from a cell surface ligand reservoir effect.

inferredcites →https://doi.org/10.1124/mol.66.4.909openalex-snapshot

Maitotoxin Induces Biphasic Interleukin-1β Secretion and Membrane Blebbing in Murine Macrophages

inferredcites →https://doi.org/10.1126/science.7535475openalex-snapshot

Altered Cytokine Export and Apoptosis in Mice Deficient in Interleukin-1β Converting Enzyme

inferredcites →https://doi.org/10.1126/science.aaf3036openalex-snapshot

An endogenous caspase-11 ligand elicits interleukin-1 release from living dendritic cells

inferredcites →https://doi.org/10.1152/physrev.00002.2012openalex-snapshot

Role of Phospholipids in Endocytosis, Phagocytosis, and Macropinocytosis

inferredcites →https://doi.org/10.1242/jcs.03377openalex-snapshot

Caspase-1-dependent processing of pro-interleukin-1β is cytosolic and precedes cell death

inferredcites →https://doi.org/10.15252/embj.201694696openalex-snapshot

GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death

inferredcites →https://doi.org/10.3389/fimmu.2015.00054openalex-snapshot

ATP-Induced IL-1β Specific Secretion: True Under Stringent Conditions

inferredcites →https://doi.org/10.4049/jimmunol.1401624openalex-snapshot

Neutrophil IL-1β Processing Induced by Pneumolysin Is Mediated by the NLRP3/ASC Inflammasome and Caspase-1 Activation and Is Dependent on K+ Efflux

inferredcites →https://doi.org/10.4049/jimmunol.1601757openalex-snapshot

MLKL Activation Triggers NLRP3-Mediated Processing and Release of IL-1β Independently of Gasdermin-D

inferredcites →https://doi.org/10.4049/jimmunol.180.11.7147openalex-snapshot

P2X7 Receptor Differentially Couples to Distinct Release Pathways for IL-1β in Mouse Macrophage

inferredcites →https://doi.org/10.7554/elife.11205openalex-snapshot

Translocation of interleukin-1β into a vesicle intermediate in autophagy-mediated secretion

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How Do Biomolecules Cross the Cell Membrane?

inferred← citeshttps://doi.org/10.1038/s41392-024-01801-8openalex-snapshot

The gasdermin family: emerging therapeutic targets in diseases

inferred← citeshttps://doi.org/10.1038/s41418-018-0212-6openalex-snapshot

Pyroptosis versus necroptosis: similarities, differences, and crosstalk

inferred← citeshttps://doi.org/10.1038/s41419-019-1723-xopenalex-snapshot

Docosahexaenoic acid inhibits both NLRP3 inflammasome assembly and JNK-mediated mature IL-1β secretion in 5-fluorouracil-treated MDSC: implication in cancer treatment

inferred← citeshttps://doi.org/10.1038/s41419-022-05191-zopenalex-snapshot

Hypoxic human proximal tubular epithelial cells undergo ferroptosis and elicit an NLRP3 inflammasome response in CD1c+ dendritic cells

inferred← citeshttps://doi.org/10.1038/s41419-022-05476-3openalex-snapshot

Lysosomal cathepsins act in concert with Gasdermin-D during NAIP/NLRC4-dependent IL-1β secretion

inferred← citeshttps://doi.org/10.1038/s41419-025-07537-9openalex-snapshot

LL37 complexed to double-stranded RNA induces RIG-I-like receptor signalling and Gasdermin E activation facilitating IL-36γ release from keratinocytes

inferred← citeshttps://doi.org/10.1038/s41419-025-07620-1openalex-snapshot

Gasdermin D deficiency aggravates nephrocalcinosis-related chronic kidney disease with rendering macrophages vulnerable to necroptosis

inferred← citeshttps://doi.org/10.1038/s41419-025-07748-0openalex-snapshot

Gasdermin E deficiency limits inflammation and lung damage during influenza virus infection

inferred← citeshttps://doi.org/10.1038/s41467-020-16043-9openalex-snapshot

N-GSDMD trafficking to neutrophil organelles facilitates IL-1β release independently of plasma membrane pores and pyroptosis

inferred← citeshttps://doi.org/10.1038/s41467-021-22979-3openalex-snapshot

The ubiquitylation of IL-1β limits its cleavage by caspase-1 and targets it for proteasomal degradation

inferred← citeshttps://doi.org/10.1038/s41467-021-27034-9openalex-snapshot

Inflammasome-mediated GSDMD activation facilitates escape of Candida albicans from macrophages

inferred← citeshttps://doi.org/10.1038/s41467-021-27692-9openalex-snapshot

Gasdermin D pores are dynamically regulated by local phosphoinositide circuitry

inferred← citeshttps://doi.org/10.1038/s41467-023-41391-7openalex-snapshot

NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity

inferred← citeshttps://doi.org/10.1038/s41467-024-50901-0openalex-snapshot

Proximity labelling of pro-interleukin-1α reveals evolutionary conserved nuclear interactions

inferred← citeshttps://doi.org/10.1038/s41467-024-52818-0openalex-snapshot

Coronavirus envelope protein activates TMED10-mediated unconventional secretion of inflammatory factors

inferred← citeshttps://doi.org/10.1038/s41467-024-55083-3openalex-snapshot

Cytokine-armed pyroptosis induces antitumor immunity against diverse types of tumors

inferred← citeshttps://doi.org/10.1038/s41556-024-01474-zopenalex-snapshot

Gasdermins as evolutionarily conserved executors of inflammation and cell death

inferred← citeshttps://doi.org/10.1038/s41564-020-00832-5openalex-snapshot

Escherichia coli Rho GTPase-activating toxin CNF1 mediates NLRP3 inflammasome activation via p21-activated kinases-1/2 during bacteraemia in mice

inferred← citeshttps://doi.org/10.1038/s41564-026-02272-zopenalex-snapshot

Gasdermins against intracellular bacterial pathogens

inferred← citeshttps://doi.org/10.1038/s41568-019-0123-yopenalex-snapshot

Diverging inflammasome signals in tumorigenesis and potential targeting

inferred← citeshttps://doi.org/10.1038/s41573-021-00154-zopenalex-snapshot

Channelling inflammation: gasdermins in physiology and disease

inferred← citeshttps://doi.org/10.1038/s41577-019-0165-0openalex-snapshot

The NLRP3 inflammasome: molecular activation and regulation to therapeutics

inferred← citeshttps://doi.org/10.1038/s41577-019-0228-2openalex-snapshot

The gasdermins, a protein family executing cell death and inflammation

inferred← citeshttps://doi.org/10.1038/s41577-024-00995-wopenalex-snapshot

Mechanistic insights from inflammasome structures

inferred← citeshttps://doi.org/10.1038/s41577-024-01075-9openalex-snapshot

Inflammasome components as new therapeutic targets in inflammatory disease

inferred← citeshttps://doi.org/10.1038/s41580-025-00869-6openalex-snapshot

Regulation of inflammatory processes by caspases

inferred← citeshttps://doi.org/10.1038/s41581-019-0158-zopenalex-snapshot

The role of inflammasomes in kidney disease

inferred← citeshttps://doi.org/10.1038/s41581-022-00621-9openalex-snapshot

Targeting innate immunity-driven inflammation in CKD and cardiovascular disease

inferred← citeshttps://doi.org/10.1038/s41586-021-03478-3openalex-snapshot

Gasdermin D pore structure reveals preferential release of mature interleukin-1

inferred← citeshttps://doi.org/10.1038/s41590-023-01656-1openalex-snapshot

E-selectin-mediated rapid NLRP3 inflammasome activation regulates S100A8/S100A9 release from neutrophils via transient gasdermin D pore formation

inferred← citeshttps://doi.org/10.1038/s41590-024-02024-3openalex-snapshot

Pyroptotic cell corpses are crowned with F-actin-rich filopodia that engage CLEC9A signaling in incoming dendritic cells

inferred← citeshttps://doi.org/10.1038/s41598-019-42298-4openalex-snapshot

Early endosome autoantigen 1 regulates IL-1β release upon caspase-1 activation independently of gasdermin D membrane permeabilization

inferred← citeshttps://doi.org/10.1038/s41598-022-11230-8openalex-snapshot

Army liposome formulation containing QS-21 render human monocyte-derived macrophages less permissive to HIV-1 infection by upregulating APOBEC3A

inferred← citeshttps://doi.org/10.1038/s41598-023-45870-1openalex-snapshot

Native low-density lipoproteins are priming signals of the NLRP3 inflammasome/interleukin-1β pathway in human adipose tissue and macrophages

inferred← citeshttps://doi.org/10.1038/s41598-026-43392-0openalex-snapshot

Analysis of the NLRP3 inflammasome components expression in triple-negative breast cancer patients with and without BRCA1 mutations

inferred← citeshttps://doi.org/10.1038/s42003-020-0871-yopenalex-snapshot

The Na,K-ATPase acts upstream of phosphoinositide PI(4,5)P2 facilitating unconventional secretion of Fibroblast Growth Factor 2

inferred← citeshttps://doi.org/10.1038/s42003-024-06882-3openalex-snapshot

Activation of the NLRP1B inflammasome by caspase-8

inferred← citeshttps://doi.org/10.1038/s44319-026-00698-4openalex-snapshot

IRF2 deficiency disrupts pyroptosis, NK cell interferon-γ production and resistance to Francisella

inferred← citeshttps://doi.org/10.1039/d4md00950aopenalex-snapshot

Towards more efficient synthetic immunomodulators: biological characterization and mechanism of action of monosaccharide-derived TLR4 agonists

inferred← citeshttps://doi.org/10.1039/d5dt01235jopenalex-snapshot

A copper complex with a thiazole-modified tridentate ligand: synthesis, structural characterization, and anticancer activity in B16-F10 melanoma cells

inferred← citeshttps://doi.org/10.1042/bcj20190472openalex-snapshot

The NLRP3 inflammasome regulates adipose tissue metabolism

inferred← citeshttps://doi.org/10.1042/bcj20210606openalex-snapshot

Cell death in skin function, inflammation, and disease

inferred← citeshttps://doi.org/10.1042/bcj20210711openalex-snapshot

No longer married to inflammasome signaling: the diverse interacting pathways leading to pyroptotic cell death

inferred← citeshttps://doi.org/10.1042/bcj20220051openalex-snapshot

Activation and manipulation of inflammasomes and pyroptosis during bacterial infections

inferred← citeshttps://doi.org/10.1042/bsr20201366openalex-snapshot

Piceatannol inhibits pyroptosis and suppresses oxLDL-induced lipid storage in macrophages by regulating miR-200a/Nrf2/GSDMD axis

inferred← citeshttps://doi.org/10.1042/bst20180179openalex-snapshot

Control of growth factor signalling by MACPF proteins

inferred← citeshttps://doi.org/10.1042/bst20200986openalex-snapshot

Great balls of fire: activation and signalling of inflammatory caspases

inferred← citeshttps://doi.org/10.1042/bst20221525openalex-snapshot

Mitochondrial DNA in cell death and inflammation

inferred← citeshttps://doi.org/10.1042/bst20230548openalex-snapshot

Molecular aspects of Interleukin-36 cytokine activation and regulation

inferred← citeshttps://doi.org/10.1042/bst20230549openalex-snapshot

New insights into Gasdermin D pore formation

inferred← citeshttps://doi.org/10.1073/pnas.2101189118openalex-snapshot

RIPK1 activates distinct gasdermins in macrophages and neutrophils upon pathogen blockade of innate immune signaling

inferred← citeshttps://doi.org/10.1073/pnas.2120287119openalex-snapshot

Electrostatic influence on IL-1 transport through the GSDMD pore

inferred← citeshttps://doi.org/10.1073/pnas.2537563123openalex-snapshot

Inflammasome adaptor protein ASC is a mechanistic checkpoint in IL-1β maturation

inferred← citeshttps://doi.org/10.1074/jbc.ra119.008009openalex-snapshot

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

inferred← citeshttps://doi.org/10.1080/08820139.2024.2312896openalex-snapshot

Role of Extracellular Vesicles in Immunity and Host Defense

inferred← citeshttps://doi.org/10.1080/15384101.2025.2574275openalex-snapshot

Enigmatic functions of ATP8B1: cholestasis, inflammation, phosphoinositide flipping, and cellular homeostasis

inferred← citeshttps://doi.org/10.1080/17460913.2024.2360798openalex-snapshot

Helicobacter pylori infection delays neutrophil apoptosis and exacerbates inflammatory response

inferred← citeshttps://doi.org/10.1083/jcb.202106123openalex-snapshot

Cholesterol promotes clustering of PI(4,5)P2 driving unconventional secretion of FGF2

inferred← citeshttps://doi.org/10.1083/jcb.202503075openalex-snapshot

TMEDs mediate versatile cargo transport in vesicle-dependent unconventional secretion

inferred← citeshttps://doi.org/10.1084/jem.20181892openalex-snapshot

Cell death–mediated cytokine release and its therapeutic implications

inferred← citeshttps://doi.org/10.1084/jem.20190314openalex-snapshot

Inflammasome signaling and regulation of interleukin-1 family cytokines

inferred← citeshttps://doi.org/10.1084/jem.20190545openalex-snapshot

Gasdermins and their role in immunity and inflammation

inferred← citeshttps://doi.org/10.1084/jem.20200649openalex-snapshot

Inflammasome signaling in human placental trophoblasts regulates immune defense against Listeria monocytogenes infection

inferred← citeshttps://doi.org/10.1089/neu.2021.0318openalex-snapshot

LDC7559 Exerts Neuroprotective Effects by Inhibiting GSDMD-Dependent Pyroptosis of Microglia in Mice with Traumatic Brain Injury

inferred← citeshttps://doi.org/10.1089/vim.2023.0138openalex-snapshot

Inflammatory Consequences: Hepatitis C Virus-Induced Inflammasome Activation and Pyroptosis

inferred← citeshttps://doi.org/10.1093/femsre/fuz004openalex-snapshot

Inner sensors of endotoxin – implications for sepsis research and therapy

inferred← citeshttps://doi.org/10.1093/infdis/jiaf099openalex-snapshot

Clinical Isolates of Antimicrobial-Resistant Enterobacter Species Can Persist in Human Macrophages Without Replication and Overt Cellular Cytotoxicity

inferred← citeshttps://doi.org/10.1093/jpp/rgaa069openalex-snapshot

Ginsenoside Rg3 ameliorates acetaminophen-induced hepatotoxicity by suppressing inflammation and oxidative stress

inferred← citeshttps://doi.org/10.1101/2021.03.15.435390openalex-snapshot

The inflammasome-activated cytokine IL-1β is targeted for ubiquitylation and proteasomal degradation to limit its inflammatory potential

inferred← citeshttps://doi.org/10.1101/2022.04.07.487503openalex-snapshot

The NLRP3 inflammasome selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates bacterial killing in vivo

inferred← citeshttps://doi.org/10.1101/2023.04.12.536539openalex-snapshot

Disulfide bridge-dependent dimerization triggers FGF2 membrane translocation into the extracellular space

inferred← citeshttps://doi.org/10.1101/2023.06.26.546506openalex-snapshot

Proximity labelling and evolutionary evidence reveal insights into IL-1α nuclear networks and function

inferred← citeshttps://doi.org/10.1101/2023.08.03.551696openalex-snapshot

An unconventional mechanism of IL-1β secretion that requires Type I IFN in lupus monocytes

inferred← citeshttps://doi.org/10.1101/2024.05.14.594157openalex-snapshot

CRISPR Double Knockout Library Reveals Synthetic Lethal Gene Pairs in Triple-Negative Breast Cancer

inferred← citeshttps://doi.org/10.1101/2024.07.01.601578openalex-snapshot

Poly(allylamine)/tripolyphosphate nanocomplex coacervate as a NLRP3-dependent systemic adjuvant for vaccine development

inferred← citeshttps://doi.org/10.1101/2025.09.03.673694openalex-snapshot

Inflammasomes and DNA Damage Orchestrate Divergent Pyroptotic Fates in Neutrophils

inferred← citeshttps://doi.org/10.1101/514125openalex-snapshot

Extracellular mycobacterial DNA drives disease progression by triggering Caspase-11-dependent pyroptosis of infected macrophages

inferred← citeshttps://doi.org/10.1101/679928openalex-snapshot

Sustained exposure to trypsin causes cells to transition into a state of reversible stemness that is amenable to transdifferentiation

inferred← citeshttps://doi.org/10.1101/cshperspect.a037028openalex-snapshot

Neutrophil Extracellular Traps in Host Defense

inferred← citeshttps://doi.org/10.1111/1348-0421.12771openalex-snapshot

Inflammasome‐associated cell death: Pyroptosis, apoptosis, and physiological implications

inferred← citeshttps://doi.org/10.1111/aji.13184openalex-snapshot

Gasdermin D: Evidence of pyroptosis in spontaneous preterm labor with sterile intra‐amniotic inflammation or intra‐amniotic infection

inferred← citeshttps://doi.org/10.1111/cmi.13373openalex-snapshot

Inflammasome activation and IL ‐1β signalling in group A Streptococcus disease

inferred← citeshttps://doi.org/10.1111/febs.15308openalex-snapshot

Double agents of cell death: novel emerging functions of apoptotic regulators

inferred← citeshttps://doi.org/10.1111/febs.70215openalex-snapshot

Gasdermins: multifunctional effectors of membrane permeabilization across cellular compartments

inferred← citeshttps://doi.org/10.1111/imm.13230openalex-snapshot

Gasdermin D‐independent release of interleukin‐1β by living macrophages in response to mycoplasmal lipoproteins and lipopeptides

inferred← citeshttps://doi.org/10.1111/imr.12892openalex-snapshot

Cross talk between intracellular pathogens and cell death

inferred← citeshttps://doi.org/10.1111/imr.13186openalex-snapshot

Pyroptosis in neutrophils: Multimodal integration of inflammasome and regulated cell death signaling pathways

inferred← citeshttps://doi.org/10.1111/imr.13410openalex-snapshot

Regulation of the NLRP3 inflammasome by autophagy and mitophagy

inferred← citeshttps://doi.org/10.1111/mmi.14891openalex-snapshot

Inflammasome and gasdermin signaling in neutrophils

inferred← citeshttps://doi.org/10.1111/odi.15013openalex-snapshot

Pyroptosis: A major trigger of excessive immune response in the gingiva

inferred← citeshttps://doi.org/10.1111/pim.12916openalex-snapshot

Neutrophils and schistosomiasis: a missing piece in pathology

inferred← citeshttps://doi.org/10.1126/sciadv.abc3465openalex-snapshot

Caspase-8–dependent gasdermin D cleavage promotes antimicrobial defense but confers susceptibility to TNF-induced lethality

inferred← citeshttps://doi.org/10.1126/sciadv.adu7985openalex-snapshot

Norovirus co-opts NINJ1 for selective protein secretion

inferred← citeshttps://doi.org/10.1126/sciadv.aeb4830openalex-snapshot

Threat assessment shapes neutrophil cell fate upon inflammasome activation

inferred← citeshttps://doi.org/10.1126/sciimmunol.aav1447openalex-snapshot

Gasdermin D activity in inflammation and host defense

inferred← citeshttps://doi.org/10.1126/scisignal.abe1757openalex-snapshot

Select hyperactivating NLRP3 ligands enhance the T H 1- and T H 17-inducing potential of human type 2 conventional dendritic cells

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