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Prolonged mitosis causes separase deregulation and chromosome nondisjunction
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1016/0165-4608(84)90113-4openalex-snapshot
Mitotic modifications and aberrations in human cervical cancer
inferredcites →https://doi.org/10.1016/j.ceb.2018.02.012openalex-snapshot
Anaphase: a fortune-teller of genomic instability
inferredcites →https://doi.org/10.1016/j.cub.2006.03.049openalex-snapshot
Human Scc4 Is Required for Cohesin Binding to Chromatin, Sister-Chromatid Cohesion, and Mitotic Progression
inferredcites →https://doi.org/10.1016/j.cub.2006.07.022openalex-snapshot
Aurora Kinase Promotes Turnover of Kinetochore Microtubules to Reduce Chromosome Segregation Errors
inferredcites →https://doi.org/10.1016/j.cub.2009.09.055openalex-snapshot
Deviant Kinetochore Microtubule Dynamics Underlie Chromosomal Instability
inferredcites →https://doi.org/10.1016/j.cub.2010.01.034openalex-snapshot
Mechanisms of Chromosomal Instability
inferredcites →https://doi.org/10.1016/j.cub.2015.08.051openalex-snapshot
The Molecular Biology of Spindle Assembly Checkpoint Signaling Dynamics
inferredcites →https://doi.org/10.1016/j.devcel.2012.06.015openalex-snapshot
Separase Sensor Reveals Dual Roles for Separase Coordinating Cohesin Cleavage and Cdk1 Inhibition
inferredcites →https://doi.org/10.1016/j.devcel.2016.02.008openalex-snapshot
HP1-Assisted Aurora B Kinase Activity Prevents Chromosome Segregation Errors
inferredcites →https://doi.org/10.1016/j.molcel.2015.03.025openalex-snapshot
Human Chromosome Segregation Involves Multi-Layered Regulation of Separase by the Peptidyl-Prolyl-Isomerase Pin1
inferredcites →https://doi.org/10.1016/j.tcb.2016.07.008openalex-snapshot
Time To Split Up: Dynamics of Chromosome Separation
inferredcites →https://doi.org/10.1038/emboj.2013.211openalex-snapshot
How unfinished business from S‐phase affects mitosis and beyond
inferredcites →https://doi.org/10.1038/nature08136openalex-snapshot
A mechanism linking extra centrosomes to chromosomal instability
inferredcites →https://doi.org/10.1038/nature11935openalex-snapshot
Replication stress links structural and numerical cancer chromosomal instability
inferredcites →https://doi.org/10.1038/nature12369openalex-snapshot
Erratum: Corrigendum: Replication stress links structural and numerical cancer chromosomal instability
inferredcites →https://doi.org/10.1038/ncb1738openalex-snapshot
Extra centrosomes and/or chromosomes prolong mitosis in human cells
inferredcites →https://doi.org/10.1038/ncb1809openalex-snapshot
Genome stability is ensured by temporal control of kinetochore–microtubule dynamics
inferredcites →https://doi.org/10.1038/ncb2842openalex-snapshot
Kinetic framework of spindle assembly checkpoint signalling
inferredcites →https://doi.org/10.1038/ncb2855openalex-snapshot
The spindle assembly checkpoint works like a rheostat rather than a toggle switch
inferredcites →https://doi.org/10.1038/onc.2013.493openalex-snapshot
MMTV-Espl1 transgenic mice develop aneuploid, estrogen receptor alpha (ERα)-positive mammary adenocarcinomas
inferredcites →https://doi.org/10.1073/pnas.0801610105openalex-snapshot
Overexpression of Separase induces aneuploidy and mammary tumorigenesis
inferredcites →https://doi.org/10.1083/jcb.200811028openalex-snapshot
Kinetochore stretching inactivates the spindle assembly checkpoint
inferredcites →https://doi.org/10.1083/jcb.201001036openalex-snapshot
Dissecting the role of MPS1 in chromosome biorientation and the spindle checkpoint through the small molecule inhibitor reversine
inferredcites →https://doi.org/10.1083/jcb.201210040openalex-snapshot
Linking abnormal mitosis to the acquisition of DNA damage
inferredcites →https://doi.org/10.1091/mbc.e16-12-0853openalex-snapshot
Spindle assembly checkpoint signaling and sister chromatid cohesion are disrupted by HPV E6-mediated transformation
inferredcites →https://doi.org/10.1111/j.1365-2184.1985.tb00642.xopenalex-snapshot
Alterations In Metaphase Durations In Cells Derived From Human Tumours
inferredcites →https://doi.org/10.1371/journal.pone.0006564openalex-snapshot
Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1007/s10577-021-09651-8openalex-snapshot
SOGA1 and SOGA2/MTCL1 are CLASP-interacting proteins required for faithful chromosome segregation in human cells
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111723openalex-snapshot
Autocleavage of Separase Suppresses its Premature Activation by Promoting Binding to Cyclin B1
inferred← citeshttps://doi.org/10.1016/j.cub.2021.01.062openalex-snapshot
Kinetochore stretching-mediated rapid silencing of the spindle-assembly checkpoint required for failsafe chromosome segregation
inferred← citeshttps://doi.org/10.1016/j.cub.2021.02.014openalex-snapshot
Chromosomal instability: Stretching the role of checkpoint silencing
inferred← citeshttps://doi.org/10.1016/j.cub.2025.09.049openalex-snapshot
Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy
inferred← citeshttps://doi.org/10.1016/j.jbc.2024.107697openalex-snapshot
Cell fate simulation reveals cancer cell features in the tumor microenvironment
inferred← citeshttps://doi.org/10.1016/j.xhgg.2025.100437openalex-snapshot
The chromosomal challenge of human embryos: Mechanisms and fundamentals
inferred← citeshttps://doi.org/10.1038/s41698-025-01101-6openalex-snapshot
KMT2C inactivation leads to PTEN downregulation and tolerance to DNA damage during cell cycle progression
inferred← citeshttps://doi.org/10.1091/mbc.e24-08-0386openalex-snapshot
M phase–specific generation of supernumerary centrioles in cancer cells
inferred← citeshttps://doi.org/10.1093/nar/gkag229openalex-snapshot
RSRC2 is a novel RNA-binding protein that safeguards mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1
inferred← citeshttps://doi.org/10.1111/cas.14989openalex-snapshot
Unraveling pathologies underlying chromosomal instability in cancers
inferred← citeshttps://doi.org/10.1111/cas.70438openalex-snapshot
Targeting Cell Cycle Vulnerabilities in Cancers: Emerging Strategies for Therapeutic Development
inferred← citeshttps://doi.org/10.1158/2159-8290.cd-23-1348openalex-snapshot
Phosphocreatine Promotes Epigenetic Reprogramming to Facilitate Glioblastoma Growth Through Stabilizing BRD2
inferred← citeshttps://doi.org/10.18297/etd/3949openalex-snapshot
Molecular mechanisms of hexavalent chromium-induced centrosome amplification.
inferred← citeshttps://doi.org/10.3389/fcell.2024.1355979openalex-snapshot
Early onset of APC/C activity renders SAC inefficient in mouse embryos
inferred← citeshttps://doi.org/10.3390/cancers13123056openalex-snapshot
Structural Chromosome Instability: Types, Origins, Consequences, and Therapeutic Opportunities
inferred← citeshttps://doi.org/10.3390/cancers13184531openalex-snapshot
Attenuated Chromosome Oscillation as a Cause of Chromosomal Instability in Cancer Cells
inferred← citeshttps://doi.org/10.3390/cells11020248openalex-snapshot
Spatial and Temporal Scaling of Microtubules and Mitotic Spindles
inferred← citeshttps://doi.org/10.5772/intechopen.99812openalex-snapshot
Background, Diagnosis, Types, Management/Prevention and Implications of Chromosomal Abnormalities
inferred← citeshttps://doi.org/10.70675/8a35d253z2bc1z4f60za910za75252660eadopenalex-snapshot
Implications de la lamine B1 dans la stabilité des télomères et la mitose
inferred← citeshttps://doi.org/10.7554/elife.80254openalex-snapshot
Inhibitors of Rho kinases (ROCK) induce multiple mitotic defects and synthetic lethality in BRCA2-deficient cells
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