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The G Protein-Coupled Receptor Agtrl1b Regulates Early Development of Myocardial Progenitors

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/aja.1002000206openalex-snapshot
Precardiac mesoderm is specified during gastrulation in quail
inferredcites →https://doi.org/10.1002/dvdy.10356openalex-snapshot
Germ‐line transmission of a myocardium‐specific GFP transgene reveals critical regulatory elements in the cardiac myosin light chain 2 promoter of zebrafish
inferredcites →https://doi.org/10.1002/dvg.1020170104openalex-snapshot
Regionalisation of cell fate and morphogenetic movement of the mesoderm during mouse gastrulation
inferredcites →https://doi.org/10.1006/bbrc.1998.9489openalex-snapshot
Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor
inferredcites →https://doi.org/10.1006/bbrc.2001.6230openalex-snapshot
Apelin (65–77) Activates Extracellular Signal-Regulated Kinases via a PTX-Sensitive G Protein
inferredcites →https://doi.org/10.1006/dbio.1996.0212openalex-snapshot
NK-2Homeobox Genes and Heart Development
inferredcites →https://doi.org/10.1006/dbio.1999.9406openalex-snapshot
Restricted Expression of Cardiac Myosin Genes Reveals Regulated Aspects of Heart Tube Assembly in Zebrafish
inferredcites →https://doi.org/10.1006/dbio.2002.0711openalex-snapshot
In Vivo Imaging of Embryonic Vascular Development Using Transgenic Zebrafish
inferredcites →https://doi.org/10.1016/0925-4773(96)00585-0openalex-snapshot
Expression of a new G protein-coupled receptor X-msr is associated with an endothelial lineage in Xenopus laevis
inferredcites →https://doi.org/10.1016/j.cardiores.2004.08.018openalex-snapshot
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
inferredcites →https://doi.org/10.1016/j.cellsig.2004.09.018openalex-snapshot
Apelin signalling: a promising pathway from cloning to pharmacology
inferredcites →https://doi.org/10.1016/j.modgep.2006.09.006openalex-snapshot
Zebrafish Angiotensin II Receptor-like 1a (agtrl1a) is expressed in migrating hypoblast, vasculature, and in multiple embryonic epithelia
inferredcites →https://doi.org/10.1016/j.neuron.2005.07.014openalex-snapshot
Assembly of Trigeminal Sensory Ganglia by Chemokine Signaling
inferredcites →https://doi.org/10.1016/j.ydbio.2006.04.452openalex-snapshot
Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo
inferredcites →https://doi.org/10.1016/j.ydbio.2006.06.028openalex-snapshot
Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis
inferredcites →https://doi.org/10.1016/s0092-8674(01)00385-3openalex-snapshot
Smoothened Mutants Reveal Redundant Roles for Shh and Ihh Signaling Including Regulation of L/R Asymmetry by the Mouse Node
inferredcites →https://doi.org/10.1016/s0092-8674(02)01135-2openalex-snapshot
Guidance of Primordial Germ Cell Migration by the Chemokine SDF-1
inferredcites →https://doi.org/10.1016/s0960-9822(02)01319-2openalex-snapshot
Zebrafish as a Model Organism for the Identification and Characterization of Drugs and Genes Affecting p53 Signaling
inferredcites →https://doi.org/10.1034/j.1600-065x.2003.00067.xopenalex-snapshot
Chemokines in the systemic organization of immunity
inferredcites →https://doi.org/10.1038/mp.a000304.01openalex-snapshot
Apelin receptor
inferredcites →https://doi.org/10.1038/nature01338openalex-snapshot
A zebrafish homologue of the chemokine receptor Cxcr4 is a germ-cell guidance receptor
inferredcites →https://doi.org/10.1074/jbc.m404149200openalex-snapshot
Regulatory Roles for APJ, a Seven-transmembrane Receptor Related to Angiotensin-type 1 Receptor in Blood Pressure in Vivo
inferredcites →https://doi.org/10.1074/jbc.m908417199openalex-snapshot
Molecular and Functional Characteristics of APJ
inferredcites →https://doi.org/10.1096/fj.04-1930fjeopenalex-snapshot
Apelin (65‐77) activates p70 S6 kinase and is mitogenic for umbilical endothelial cells
inferredcites →https://doi.org/10.1101/gad.11.4.451openalex-snapshot
A role for bone morphogenetic proteins in the induction of cardiac myogenesis.
inferredcites →https://doi.org/10.1101/gad.855601openalex-snapshot
Wnt antagonism initiates cardiogenesis in Xenopus laevis
inferredcites →https://doi.org/10.1126/science.1101573openalex-snapshot
Retinoic Acid Signaling Restricts the Cardiac Progenitor Pool
inferredcites →https://doi.org/10.1161/01.cir.0000091235.94914.75openalex-snapshot
Novel Role for the Potent Endogenous Inotrope Apelin in Human Cardiac Dysfunction
inferredcites →https://doi.org/10.1242/dev.00640openalex-snapshot
The chemokine SDF1/CXCL12 and its receptor CXCR4 regulate mouse germ cell migration and survival
inferredcites →https://doi.org/10.1242/dev.01145openalex-snapshot
The ascidianMespgene specifies heart precursor cells
inferredcites →https://doi.org/10.1242/dev.01185openalex-snapshot
Organization of cardiac chamber progenitors in the zebrafish blastula
inferredcites →https://doi.org/10.1242/dev.01970openalex-snapshot
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
inferredcites →https://doi.org/10.1242/dev.02051openalex-snapshot
Uncoupling heart cell specification and migration in the simple chordateCiona intestinalis
inferredcites →https://doi.org/10.1242/dev.02087openalex-snapshot
Cellular and molecular analyses of vascular tube and lumen formation in zebrafish
inferredcites →https://doi.org/10.1242/dev.119.1.31openalex-snapshot
Cardiovascular development in the zebrafish I. Myocardial fate map and heart tube formation
inferredcites →https://doi.org/10.1242/dev.121.10.3141openalex-snapshot
cloche, an early acting zebrafish gene, is required by both the endothelial and hematopoietic lineages
inferredcites →https://doi.org/10.1242/dev.126.12.2643openalex-snapshot
Cell-autonomous and non-autonomous requirements for the zebrafish gene cloche in hematopoiesis
inferredcites →https://doi.org/10.1242/dev.126.15.3437openalex-snapshot
MesP1 is expressed in the heart precursor cells and required for the formation of a single heart tube
inferredcites →https://doi.org/10.1242/dev.127.15.3215openalex-snapshot
MesP1 and MesP2 are essential for the development of cardiac mesoderm
inferredcites →https://doi.org/10.1242/dev.127.2.225openalex-snapshot
Induction and differentiation of the zebrafish heart requires fibroblast growth factor 8 (fgf8/acerebellar)
inferredcites →https://doi.org/10.1242/dev.127.9.1953openalex-snapshot
Laser-induced gene expression in specific cells of transgenic zebrafish
inferredcites →https://doi.org/10.1371/journal.pbio.0000080openalex-snapshot
Tre1, a G Protein-Coupled Receptor, Directs Transepithelial Migration of Drosophila Germ Cells
inferredcites →https://doi.org/10.3892/ijmm.16.5.787openalex-snapshot
G protein-coupled APJ receptor signaling induces focal adhesion formation and cell motility

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4122571openalex-extracted
APJ+ Cells in the SHF Contribute to Aorta and Pulmonary Trunk Through APJ and Canonical WNT Signaling Pathways
inferred← citeshttps://doi.org/10.1002/9783527626236.ch8openalex-snapshot
Apelin and Vasopressin
inferred← citeshttps://doi.org/10.1002/bies.201400048openalex-snapshot
Small proteins, big roles: The signaling protein Apela extends the complexity of developmental pathways in the early zebrafish embryo
inferred← citeshttps://doi.org/10.1002/cbin.10581openalex-snapshot
Apelin: an endogenous peptide essential for cardiomyogenic differentiation of mesenchymal stem cells via activating extracellular signal‐regulated kinase 1/2 and 5
inferred← citeshttps://doi.org/10.1002/cphy.c170028openalex-snapshot
Apelinergic System Structure and Function
inferred← citeshttps://doi.org/10.1002/dvg.20340openalex-snapshot
Small heat shock protein Hsp27 is required for proper heart tube formation
inferred← citeshttps://doi.org/10.1002/hep.22467openalex-snapshot
The hepatic apelin system
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2018.tb00012.xopenalex-snapshot
Apelinergic System Structure and Function
inferred← citeshttps://doi.org/10.1002/jcp.26492openalex-snapshot
Biological functions of Elabela, a novel endogenous ligand of APJ receptor
inferred← citeshttps://doi.org/10.1002/wsbm.112openalex-snapshot
Signaling pathways in early cardiac development
inferred← citeshttps://doi.org/10.1007/5584_2020_567openalex-snapshot
Apelin Receptor Signaling During Mesoderm Development
inferred← citeshttps://doi.org/10.1007/978-2-8178-0466-8_6openalex-snapshot
Apelin Signaling in Retinal Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-030-26780-3_9openalex-snapshot
Ferroptosis in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1007/978-3-031-39171-2_8openalex-snapshot
Ferroptosis in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-41677-9_7openalex-snapshot
Apelin and Cancer
inferred← citeshttps://doi.org/10.1007/978-3-319-75935-7_13openalex-snapshot
Challenges of Endocrine Disruption and Cardiac Development
inferred← citeshttps://doi.org/10.1007/978-3-642-37078-6_144openalex-snapshot
Pathophysiology of Portal Hypertension
inferred← citeshttps://doi.org/10.1007/978-3-642-37393-0_144-1openalex-snapshot
Pathophysiology of Portal Hypertension
inferred← citeshttps://doi.org/10.1007/bf03165767openalex-snapshot
Expanding role for the apelin/APJ system in physiopathology
inferred← citeshttps://doi.org/10.1007/s00395-015-0521-6openalex-snapshot
Characterization of apela, a novel endogenous ligand of apelin receptor, in the adult heart
inferred← citeshttps://doi.org/10.1007/s00427-012-0403-yopenalex-snapshot
Identification and developmental expression of leucine-rich repeat-containing G protein-coupled receptor 6 (lgr6) in the medaka fish, Oryzias latipes
inferred← citeshttps://doi.org/10.1007/s10741-017-9652-1openalex-snapshot
De novo implantation vs. upgrade cardiac resynchronization therapy: a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1007/s10989-013-9374-8openalex-snapshot
Apelin-13 Inhibits Apoptosis of Cortical Neurons Following Brain Ischemic Reperfusion Injury in a Transient Model of Focal Cerebral Ischemia
inferred← citeshttps://doi.org/10.1007/s12031-012-9808-3openalex-snapshot
Apelin-13 Protects the Brain Against Ischemic Reperfusion Injury and Cerebral Edema in a Transient Model of Focal Cerebral Ischemia
inferred← citeshttps://doi.org/10.1016/b978-0-12-381332-9.00004-9openalex-snapshot
Cardiac Development in the Zebrafish
inferred← citeshttps://doi.org/10.1016/b978-0-12-381332-9.00009-8openalex-snapshot
The Behavior of Cells that Form the Myocardial Compartments of the Vertebrate Heart
inferred← citeshttps://doi.org/10.1016/b978-0-12-381510-1.00003-xopenalex-snapshot
Cardiac Myocyte Specification and Differentiation
inferred← citeshttps://doi.org/10.1016/b978-0-12-386930-2.00004-5openalex-snapshot
Zebrafish as a Model of Cardiac Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-387786-4.00001-4openalex-snapshot
Life Before Nkx2.5
inferred← citeshttps://doi.org/10.1016/b978-0-12-394587-7.00005-1openalex-snapshot
GPCRs in Stem Cell Function
inferred← citeshttps://doi.org/10.1016/j.ajpath.2011.08.024openalex-snapshot
Apelin Attenuates UVB-Induced Edema and Inflammation by Promoting Vessel Function
inferred← citeshttps://doi.org/10.1016/j.bcp.2016.07.018openalex-snapshot
Cardiac action of the first G protein biased small molecule apelin agonist
inferred← citeshttps://doi.org/10.1016/j.biopha.2023.115268openalex-snapshot
Therapeutic potential of apelin and Elabela in cardiovascular disease
inferred← citeshttps://doi.org/10.1016/j.cyto.2020.155003openalex-snapshot
Insight into adipokines to optimize therapeutic effects of stem cell for tissue regeneration
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2019.03.003openalex-snapshot
Elabela and Apelin actions in healthy and pathological pregnancies
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.02.005openalex-snapshot
Apelin and Its G Protein-Coupled Receptor Regulate Cardiac Development as Well as Cardiac Function
inferred← citeshttps://doi.org/10.1016/j.devcel.2013.11.002openalex-snapshot
ELABELA: A Hormone Essential for Heart Development Signals via the Apelin Receptor
inferred← citeshttps://doi.org/10.1016/j.devcel.2017.08.008openalex-snapshot
Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts
inferred← citeshttps://doi.org/10.1016/j.diff.2012.05.005openalex-snapshot
Zebrafish models in cardiac development and congenital heart birth defects
inferred← citeshttps://doi.org/10.1016/j.ejheart.2008.06.002openalex-snapshot
The Role of Apelin in Cardiovascular Function and Heart Failure
inferred← citeshttps://doi.org/10.1016/j.ejphar.2015.05.017openalex-snapshot
Apelin receptors: From signaling to antidiabetic strategy
inferred← citeshttps://doi.org/10.1016/j.gde.2008.07.011openalex-snapshot
Back and forth between cell fate specification and movement during vertebrate gastrulation
inferred← citeshttps://doi.org/10.1016/j.ijcard.2016.07.263openalex-snapshot
Apelin-13 infusion salvages the peri-infarct region to preserve cardiac function after severe myocardial injury
inferred← citeshttps://doi.org/10.1016/j.mce.2014.08.009openalex-snapshot
Molecular and physiological evidences for the role in appetite regulation of apelin and its receptor APJ in Ya-fish (Schizothorax prenanti)
inferred← citeshttps://doi.org/10.1016/j.peptides.2009.04.020openalex-snapshot
Apelin in goldfish (Carassius auratus): Cloning, distribution and role in appetite regulation
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.10.010openalex-snapshot
The apelinergic system in the developing lung: Expression and signaling
inferred← citeshttps://doi.org/10.1016/j.peptides.2012.03.005openalex-snapshot
Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat
inferred← citeshttps://doi.org/10.1016/j.peptides.2018.04.011openalex-snapshot
Apelin and Elabela/Toddler; double ligands for APJ/Apelin receptor in heart development, physiology, and pathology
inferred← citeshttps://doi.org/10.1016/j.peptides.2021.170674openalex-snapshot
Effects and signaling pathways of Elabela in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.pharmr.2026.100130openalex-snapshot
International Union of Basic and Clinical Pharmacology. CXXI. Apelin receptor pharmacology in the human cardiovascular system and emerging clinical applications
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2010.09.003openalex-snapshot
Adipocytokines, cardiovascular pathophysiology and myocardial protection
inferred← citeshttps://doi.org/10.1016/j.regpep.2007.10.002openalex-snapshot
Apelin reduces myocardial reperfusion injury independently of PI3K/Akt and P70S6 kinase
inferred← citeshttps://doi.org/10.1016/j.stem.2010.11.011openalex-snapshot
A Mesoderm-Derived Precursor for Mesenchymal Stem and Endothelial Cells
inferred← citeshttps://doi.org/10.1016/j.stemcr.2021.02.003openalex-snapshot
Modulation of APLNR Signaling Is Required during the Development and Maintenance of the Hematopoietic System
inferred← citeshttps://doi.org/10.1016/j.tips.2015.06.002openalex-snapshot
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.vph.2023.107193openalex-snapshot
Cardiovascular aspects of ELABELA: A potential diagnostic biomarker and therapeutic target
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.08.001openalex-snapshot
The orphan G protein-coupled receptor 161 is required for left–right patterning
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.02.010openalex-snapshot
Differential requirement for BMP signaling in atrial and ventricular lineages establishes cardiac chamber proportionality
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.08.022openalex-snapshot
Mespaa can potently induce cardiac fates in zebrafish
inferred← citeshttps://doi.org/10.1016/j.ydbio.2023.04.003openalex-snapshot
APJ+ cells in the SHF contribute to the cells of aorta and pulmonary trunk through APJ signaling
inferred← citeshttps://doi.org/10.1016/s0070-2153(09)89007-8openalex-snapshot
Chapter 7 Convergence and Extension Movements During Vertebrate Gastrulation
inferred← citeshttps://doi.org/10.1016/s1546-5098(10)02905-5openalex-snapshot
Endocrinology of zebrafish
inferred← citeshttps://doi.org/10.1038/nature11263openalex-snapshot
APJ acts as a dual receptor in cardiac hypertrophy
inferred← citeshttps://doi.org/10.1038/ncomms11805openalex-snapshot
In vivo modulation of endothelial polarization by Apelin receptor signalling
inferred← citeshttps://doi.org/10.1038/ncomms7020openalex-snapshot
Genetic targeting of sprouting angiogenesis using Apln-CreER
inferred← citeshttps://doi.org/10.1038/nrm2154openalex-snapshot
In Brief
inferred← citeshttps://doi.org/10.1038/s41467-019-09831-5openalex-snapshot
Functional cardiac fibroblasts derived from human pluripotent stem cells via second heart field progenitors
inferred← citeshttps://doi.org/10.1038/s41467-021-26966-6openalex-snapshot
Single cell multi-omic analysis identifies a Tbx1-dependent multilineage primed population in murine cardiopharyngeal mesoderm
inferred← citeshttps://doi.org/10.1038/s41467-025-63003-2openalex-snapshot
Apelin as a CNS-specific pathway for fenestrated capillary formation in the choroid plexus
inferred← citeshttps://doi.org/10.1038/s41556-022-00947-3openalex-snapshot
Mesp1 controls the chromatin and enhancer landscapes essential for spatiotemporal patterning of early cardiovascular progenitors
inferred← citeshttps://doi.org/10.1038/s41581-021-00461-zopenalex-snapshot
The therapeutic potential of apelin in kidney disease
inferred← citeshttps://doi.org/10.1038/s41594-022-00797-5openalex-snapshot
Structural insight into apelin receptor-G protein stoichiometry
inferred← citeshttps://doi.org/10.1038/s44318-025-00441-0openalex-snapshot
Early coordination of cell migration and cardiac fate determination during mammalian gastrulation
inferred← citeshttps://doi.org/10.1038/s44319-025-00656-6openalex-snapshot
Apelin signaling acts as a molecular switch between endothelial and hematopoietic stem cell fates
inferred← citeshttps://doi.org/10.1038/sj.emboj.7601982openalex-snapshot
Spatial and temporal role of the apelin/APJ system in the caliber size regulation of blood vessels during angiogenesis
inferred← citeshttps://doi.org/10.1042/etls20230084openalex-snapshot
Signaling mechanisms that direct cell fate specification and morphogenesis in human embryonic stem cells-based models of human gastrulation
inferred← citeshttps://doi.org/10.1051/jbio/2009021openalex-snapshot
Signalisation apeline et physiopathologie vasculaire
inferred← citeshttps://doi.org/10.1074/jbc.m109.069948openalex-snapshot
G Protein βγ Subunits Regulate Cell Adhesion through Rap1a and Its Effector Radil
inferred← citeshttps://doi.org/10.1080/0886022x.2020.1792926openalex-snapshot
Serum elabela and apelin levels during different stages of chronic kidney disease
inferred← citeshttps://doi.org/10.1089/scd.2011.0584openalex-snapshot
Involvement of Metabotropic Glutamate Receptor 5 in Cardiomyocyte Differentiation from Mouse Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1093/abbs/gmu032openalex-snapshot
ELABELA: a novel hormone in cardiac development acting as a new endogenous ligand for the APJ receptor
inferred← citeshttps://doi.org/10.1093/abbs/gmu046openalex-snapshot
A static pressure sensitive receptor APJ promote H9c2 cardiomyocyte hypertrophy via PI3K-autophagy pathway
inferred← citeshttps://doi.org/10.1093/abbs/gmx098openalex-snapshot
Elabela-APJ axis: a novel therapy target for cardiovascular diseases
inferred← citeshttps://doi.org/10.1093/cvr/cvr098openalex-snapshot
Zebrafish as a model to study cardiac development and human cardiac disease
inferred← citeshttps://doi.org/10.1093/cvr/cvt166openalex-snapshot
The G-protein-coupled receptor APJ is expressed in the second heart field and regulates Cerberus–Baf60c axis in embryonic stem cell cardiomyogenesis
inferred← citeshttps://doi.org/10.1093/cvr/cvx061openalex-snapshot
ELABELA-APJ axis protects from pressure overload heart failure and angiotensin II-induced cardiac damage
inferred← citeshttps://doi.org/10.1096/fj.09-140715openalex-snapshot
Identification and pharmacological properties of E339–3D6, the first nonpeptidic apelin receptor agonist
inferred← citeshttps://doi.org/10.1097/fjc.0000000000000803openalex-snapshot
Essential Role of the ELABELA-APJ Signaling Pathway in Cardiovascular System Development and Diseases
inferred← citeshttps://doi.org/10.1101/199638openalex-snapshot
Hey2 restricts cardiac progenitor addition to the developing heart
inferred← citeshttps://doi.org/10.1101/2020.09.01.278366openalex-snapshot
An intestinal cell type in zebrafish is the nexus for the SARS-CoV-2 receptor and the Renin-Angiotensin-Aldosterone System that contributes to COVID-19 comorbidities
inferred← citeshttps://doi.org/10.1111/febs.16048openalex-snapshot
Critical APJ receptor residues in extracellular domains that influence effector selectivity
inferred← citeshttps://doi.org/10.1111/j.1095-8649.2008.02125.xopenalex-snapshot
The outflow tract of the heart in fishes: anatomy, genes and evolution
inferred← citeshttps://doi.org/10.1124/pr.110.002949openalex-snapshot
International Union of Basic and Clinical Pharmacology. LXXIV. Apelin Receptor Nomenclature, Distribution, Pharmacology, and Function
inferred← citeshttps://doi.org/10.1124/pr.119.017533openalex-snapshot
International Union of Basic and Clinical Pharmacology. CVII. Structure and Pharmacology of the Apelin Receptor with a Recommendation that Elabela/Toddler Is a Second Endogenous Peptide Ligand
inferred← citeshttps://doi.org/10.1126/sciadv.abg0834openalex-snapshot
GATA4/5/6 family transcription factors are conserved determinants of cardiac versus pharyngeal mesoderm fate
inferred← citeshttps://doi.org/10.1126/sciadv.add2488openalex-snapshot
A self-generated Toddler gradient guides mesodermal cell migration
inferred← citeshttps://doi.org/10.1126/science.1160038openalex-snapshot
Chemokine Signaling Controls Endodermal Migration During Zebrafish Gastrulation
inferred← citeshttps://doi.org/10.1126/science.1248636openalex-snapshot
Toddler: An Embryonic Signal That Promotes Cell Movement via Apelin Receptors
inferred← citeshttps://doi.org/10.1146/annurev-cellbio-012125-115503openalex-snapshot
Zebrafish Gastrulation
inferred← citeshttps://doi.org/10.1146/annurev-cellbio-112122-030209openalex-snapshot
Nodal Signaling: A Paradigm for TGFβ Signaling in Embryonic Development
inferred← citeshttps://doi.org/10.1146/annurev-genet-110711-155646openalex-snapshot
Uncovering the Molecular and Cellular Mechanisms of Heart Development Using the Zebrafish
inferred← citeshttps://doi.org/10.1152/ajpheart.00366.2012openalex-snapshot
Apelin-13 increases myocardial progenitor cells and improves repair postmyocardial infarction
inferred← citeshttps://doi.org/10.1152/ajpheart.00686.2009openalex-snapshot
Endogenous regulation of cardiovascular function by apelin-APJ
inferred← citeshttps://doi.org/10.1152/ajpheart.00693.2017openalex-snapshot
Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition
inferred← citeshttps://doi.org/10.1152/ajpheart.00935.2007openalex-snapshot
In vivo genetic profiling and cellular localization of apelin reveals a hypoxia-sensitive, endothelial-centered pathway activated in ischemic heart failure
inferred← citeshttps://doi.org/10.1152/ajpregu.00422.2009openalex-snapshot
The effects of apelin treatment on skeletal muscle mitochondrial content
inferred← citeshttps://doi.org/10.1160/th08-06-0358openalex-snapshot
Maturation of blood vessels by haematopoietic stem cells and progenitor cells: Involvement of apelin/APJ and angiopoietin/Tie2 interactions in vessel caliber size regulation
inferred← citeshttps://doi.org/10.1161/atvbaha.108.174847openalex-snapshot
Apelin-APJ Signaling in Retinal Angiogenesis
inferred← citeshttps://doi.org/10.1161/atvbaha.113.302785openalex-snapshot
Essential Role of Apelin Signaling During Lymphatic Development in Zebrafish
inferred← citeshttps://doi.org/10.1161/atvbaha.113.302905openalex-snapshot
Apelin Signaling
inferred← citeshttps://doi.org/10.1161/circresaha.108.188805openalex-snapshot
Arterial–Venous Specification During Development
inferred← citeshttps://doi.org/10.1161/circresaha.109.201186openalex-snapshot
G Protein-Coupled Receptor APJ and Its Ligand Apelin Act Downstream of Cripto to Specify Embryonic Stem Cells Toward the Cardiac Lineage Through Extracellular Signal-Regulated Kinase/p70S6 Kinase Signaling Pathway
inferred← citeshttps://doi.org/10.1161/circresaha.109.203042openalex-snapshot
Why Don't They Beat?
inferred← citeshttps://doi.org/10.1161/circresaha.110.217950openalex-snapshot
Tbx5 and Bmp Signaling Are Essential for Proepicardium Specification in Zebrafish
inferred← citeshttps://doi.org/10.1161/circresaha.113.301324openalex-snapshot
Apelin-APJ Signaling Is a Critical Regulator of Endothelial MEF2 Activation in Cardiovascular Development
inferred← citeshttps://doi.org/10.1161/circresaha.113.301632openalex-snapshot
A Novel APJ Signaling Cascade That Regulates Cardiovascular Development
inferred← citeshttps://doi.org/10.1161/circulationaha.113.007822openalex-snapshot
ERG-APLNR Axis Controls Pulmonary Venule Endothelial Proliferation in Pulmonary Veno-Occlusive Disease
inferred← citeshttps://doi.org/10.1172/jci69608openalex-snapshot
Apelin is a positive regulator of ACE2 in failing hearts
inferred← citeshttps://doi.org/10.1182/blood-2011-12-396093openalex-snapshot
APELIN promotes hematopoiesis from human embryonic stem cells
inferred← citeshttps://doi.org/10.1186/1756-0500-2-231openalex-snapshot
Zebrafish aplnra functions in epiboly
inferred← citeshttps://doi.org/10.1186/s12861-015-0090-9openalex-snapshot
Med14 cooperates with brg1 in the differentiation of skeletogenic neural crest
inferred← citeshttps://doi.org/10.1242/bio.058172openalex-snapshot
The SARS-CoV-2 receptor and other key components of the Renin-Angiotensin-Aldosterone System related to COVID-19 are expressed in enterocytes in larval zebrafish
inferred← citeshttps://doi.org/10.1242/bio.2012380openalex-snapshot
The Aplnr GPCR regulates myocardial progenitor development via a novel cell-non-autonomous, Gαi/o protein-independent pathway
inferred← citeshttps://doi.org/10.1242/dev.020107openalex-snapshot
Sdf1/Cxcr4 signaling controls the dorsal migration of endodermal cells during zebrafish gastrulation
inferred← citeshttps://doi.org/10.1242/dev.020396openalex-snapshot
Sphingosine-1-phosphate receptors regulate individual cell behaviours underlying the directed migration of prechordal plate progenitor cells during zebrafish gastrulation
inferred← citeshttps://doi.org/10.1242/dev.024083openalex-snapshot
Hedgehog signaling plays a cell-autonomous role in maximizing cardiac developmental potential
inferred← citeshttps://doi.org/10.1242/dev.064279openalex-snapshot
Smarcd3b and Gata5 promote a cardiac progenitor fate in the zebrafish embryo
inferred← citeshttps://doi.org/10.1242/dev.158477openalex-snapshot
In vivo imaging of emerging endocrine cells reveals a requirement for PI3K-regulated motility in pancreatic islet morphogenesis
inferred← citeshttps://doi.org/10.1242/dev.163535openalex-snapshot
Nodal signaling has dual roles in fate specification and directed migration during germ layer segregation in zebrafish
inferred← citeshttps://doi.org/10.1242/dev.167510openalex-snapshot
Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development
inferred← citeshttps://doi.org/10.1247/csf.18005openalex-snapshot
Hidden Peptides Encoded by Putative Noncoding RNAs
inferred← citeshttps://doi.org/10.1371/journal.pbio.1001403openalex-snapshot
Chemokine GPCR Signaling Inhibits β-Catenin during Zebrafish Axis Formation
inferred← citeshttps://doi.org/10.1371/journal.pone.0007780openalex-snapshot
Gi-Coupled GPCR Signaling Controls the Formation and Organization of Human Pluripotent Colonies
inferred← citeshttps://doi.org/10.1371/journal.pone.0009105openalex-snapshot
G Protein Coupled Receptors in Embryonic Stem Cells: A Role for Gs-Alpha Signaling
inferred← citeshttps://doi.org/10.1371/journal.pone.0038328openalex-snapshot
Apelin Enhances Directed Cardiac Differentiation of Mouse and Human Embryonic Stem Cells
inferred← citeshttps://doi.org/10.1371/journal.pone.0056981openalex-snapshot
Postnatal Overfeeding Causes Early Shifts in Gene Expression in the Heart and Long-Term Alterations in Cardiometabolic and Oxidative Parameters
inferred← citeshttps://doi.org/10.1371/journal.pone.0070053openalex-snapshot
Full Transcriptome Analysis of Early Dorsoventral Patterning in Zebrafish
inferred← citeshttps://doi.org/10.1371/journal.pone.0183094openalex-snapshot
Expression and functional implications of the renal apelinergic system in rodents
inferred← citeshttps://doi.org/10.1517/14728221003752743openalex-snapshot
The apelinergic system: a promising therapeutic target
inferred← citeshttps://doi.org/10.1530/joe-12-0232openalex-snapshot
Role of adipokines in cardiovascular disease
inferred← citeshttps://doi.org/10.15476/elte.2017.122openalex-snapshot
Az embrionális fejlődés során zajló sejtmozgások szabályozásának vizsgálata zebradánió modellben
inferred← citeshttps://doi.org/10.17615/ydd8-g533openalex-snapshot
Functional analysis of CASTOR in vertebrate cardiomyocyte differentiation
inferred← citeshttps://doi.org/10.17912/micropub.biology.000886openalex-snapshot
Elabela and Apelin regulate coronary angiogenesis in a competitive manner
inferred← citeshttps://doi.org/10.18452/15818openalex-snapshot
Function of the alpha1B1 subunit of Na +, K + ATPase during zebrafish heart development
inferred← citeshttps://doi.org/10.22038/ijbms.2018.24796.6165openalex-snapshot
Mild exercise along with limb blood-flow restriction modulates the electrocardiogram, angiotensin, and apelin receptors of the heart in aging rats.
inferred← citeshttps://doi.org/10.2515/therapie/2009045openalex-snapshot
Effet de l’apéline sur le système cardiovasculaire et le métabolisme hydrique
inferred← citeshttps://doi.org/10.29252/mlj.11.5.27openalex-snapshot
Effect of 8-Week Aerobic, Strength and Concurrent Training on Circulating Apelin in Morphine-Dependent Rats
inferred← citeshttps://doi.org/10.32657/10356/180359openalex-snapshot
Use of the zebrafish model for target identification for host-directed therapies against tuberculosis
inferred← citeshttps://doi.org/10.3389/fcell.2015.00076openalex-snapshot
G-protein Coupled Receptor Signaling in Pluripotent Stem Cell-derived Cardiovascular Cells: Implications for Disease Modeling
inferred← citeshttps://doi.org/10.3389/fendo.2018.00756openalex-snapshot
Characterization of the Apelin/Elabela Receptors (APLNR) in Chickens, Turtles, and Zebrafish: Identification of a Novel Apelin-Specific Receptor in Teleosts
inferred← citeshttps://doi.org/10.3390/cells8111311openalex-snapshot
Roles of the Hepatic Endocannabinoid and Apelin Systems in the Pathogenesis of Liver Fibrosis
inferred← citeshttps://doi.org/10.3390/genes13112172openalex-snapshot
Distribution, Function, and Expression of the Apelinergic System in the Healthy and Diseased Mammalian Brain
inferred← citeshttps://doi.org/10.3390/ijms22031330openalex-snapshot
Reorganization of Metabolism during Cardiomyogenesis Implies Time-Specific Signaling Pathway Regulation
inferred← citeshttps://doi.org/10.3390/ijms24098014openalex-snapshot
The Apelinergic System in Pregnancy
inferred← citeshttps://doi.org/10.3390/jcdd8020015openalex-snapshot
Atrial and Sinoatrial Node Development in the Zebrafish Heart
inferred← citeshttps://doi.org/10.36290/vnl.2020.035openalex-snapshot
Adipocytokines and thyreopathies
inferred← citeshttps://doi.org/10.3727/096368909x474843openalex-snapshot
Increased Apelin following Bone Marrow Mononuclear Cell Transplantation Contributes to the Improvement of Cardiac Function in Patients with Severe Heart Failure
inferred← citeshttps://doi.org/10.3727/096368910x504450openalex-snapshot
The Apelin-APJ Pathway Exists in Cardiomyogenic Cells Derived from Mesenchymal Stem Cells In Vitro and in Vivo
inferred← citeshttps://doi.org/10.3727/096368916x691123openalex-snapshot
Activation of Endogenous Cardiac Stem Cells by Apelin-13 in Infarcted Rat Heart
inferred← citeshttps://doi.org/10.5603/ah.a2022.0016openalex-snapshot
Elabela: novel perspectives on vascular physiology and disease
inferred← citeshttps://doi.org/10.5603/gp.a2021.0246openalex-snapshot
Elabela levels in pregnancies with intrauterine growth retardation
inferred← citeshttps://doi.org/10.5772/14304openalex-snapshot
Embryonic Stem Cells as a Model System to Elucidate Early Events in Cardiac Specification and Determination
inferred← citeshttps://doi.org/10.5772/26645openalex-snapshot
Apelin Signalling: Lineage Marker and Functional Actor of Blood Vessel Formation
inferred← citeshttps://doi.org/10.64898/2026.04.01.715778openalex-snapshot
Vegfc–Vegfr3-Dependent Lymphatic Sprouting Requires Apelin Signaling
inferred← citeshttps://doi.org/10.7150/ijbs.30100openalex-snapshot
Aplnra/b Sequentially Regulate Organ Left-Right Patterning via Distinct Mechanisms
inferred← citeshttps://doi.org/10.7554/elife.06726openalex-snapshot
The hormonal peptide Elabela guides angioblasts to the midline during vasculogenesis
inferred← citeshttps://doi.org/10.7554/elife.13758openalex-snapshot
The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development
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