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Molecular and Functional Characteristics of APJ
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1006/bbrc.1997.6252openalex-snapshot
Identification and Characterization of a Novel Human Cortistatin-like Peptide
inferredcites →https://doi.org/10.1006/bbrc.1998.9489openalex-snapshot
Isolation and Characterization of a Novel Endogenous Peptide Ligand for the Human APJ Receptor
inferredcites →https://doi.org/10.1007/s001090050403openalex-snapshot
The quest for novel bioactive peptides utilizing orphan seven-transmembrane-domain receptors
inferredcites →https://doi.org/10.1016/0006-291x(80)91415-1openalex-snapshot
Isolation and amino acid composition of two somatostatin-like peptides from ovine hypothalamus: Somatostatin-28 and somatostatin-25
inferredcites →https://doi.org/10.1016/0006-291x(90)91222-eopenalex-snapshot
Molecular identification of receptor for pituitary adenylate cyclase activating polypeptide
inferredcites →https://doi.org/10.1016/0378-1119(93)90495-oopenalex-snapshot
A human gene that shows identity with the gene encoding the angiotensin receptor is located on chromosome 11
inferredcites →https://doi.org/10.1016/s0167-4889(99)00114-7openalex-snapshot
Apelin, the natural ligand of the orphan receptor APJ, is abundantly secreted in the colostrum
inferredcites →https://doi.org/10.1016/s1043-9471(05)80042-4openalex-snapshot
[12] Regulation of Na+-H+ exchange by G protein-coupled receptors
inferredcites →https://doi.org/10.1038/30515openalex-snapshot
A prolactin-releasing peptide in the brain
inferredcites →https://doi.org/10.1038/377532a0openalex-snapshot
Isolation and structure of the endogenous agonist of opioid receptor-like ORL1 receptor
inferredcites →https://doi.org/10.1073/pnas.95.19.11360openalex-snapshot
HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors
inferredcites →https://doi.org/10.1111/j.1749-6632.1949.tb27297.xopenalex-snapshot
THE ATTRACTIONS OF PROTEINS FOR SMALL MOLECULES AND IONS
inferredcites →https://doi.org/10.1126/science.270.5237.792openalex-snapshot
Orphanin FQ: A Neuropeptide That Activates an Opioidlike G Protein-Coupled Receptor
inferredcites →https://doi.org/10.1128/jvi.72.10.7934-7940.1998openalex-snapshot
An Orphan Seven-Transmembrane Domain Receptor Expressed Widely in the Brain Functions as a Coreceptor for Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus
inferredcites →https://doi.org/10.1128/jvi.72.7.6113-6118.1998openalex-snapshot
The Orphan Seven-Transmembrane Receptor Apj Supports the Entry of Primary T-Cell-Line-Tropic and Dualtropic Human Immunodeficiency Virus Type 1
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/1873-3468.13344openalex-snapshot
Molecular determinants on extracellular loop domains that dictate interaction between β‐arrestin and human APJ receptor
inferred← citeshttps://doi.org/10.1002/bip.22498openalex-snapshot
Stability and degradation patterns of chemically modified analogs of apelin‐13 in plasma and cerebrospinal fluid
inferred← citeshttps://doi.org/10.1002/cmdc.201000061openalex-snapshot
Exploring the ‘RPRL’ Motif of Apelin‐13 through Molecular Simulation and Biological Evaluation of Cyclic Peptide Analogues
inferred← citeshttps://doi.org/10.1002/cphy.c170028openalex-snapshot
Apelinergic System Structure and Function
inferred← citeshttps://doi.org/10.1002/hep.31545openalex-snapshot
The Apelin–Apelin Receptor Axis Triggers Cholangiocyte Proliferation and Liver Fibrosis During Mouse Models of Cholestasis
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2018.tb00012.xopenalex-snapshot
Apelinergic System Structure and Function
inferred← citeshttps://doi.org/10.1002/jat.4405openalex-snapshot
Potential role of the apelin‐APJ pathway in sex‐related differential cardiotoxicity induced by doxorubicin in mice
inferred← citeshttps://doi.org/10.1002/jcp.26144openalex-snapshot
Apelin/APJ system: A novel potential therapy target for kidney disease
inferred← citeshttps://doi.org/10.1002/jcp.26554openalex-snapshot
ROS‐Autophagy pathway mediates monocytes‐human umbilical vein endothelial cells adhesion induced by apelin‐13
inferred← citeshttps://doi.org/10.1002/jcp.27047openalex-snapshot
Targeting drugs to APJ receptor: From signaling to pathophysiological effects
inferred← citeshttps://doi.org/10.1002/jcp.27720openalex-snapshot
Function and regulation of apelin/APJ system in digestive physiology and pathology
inferred← citeshttps://doi.org/10.1006/bbrc.2002.6575openalex-snapshot
The Effects of Centrally Administered Apelin-13 on Food Intake, Water Intake and Pituitary Hormone Release in Rats
inferred← citeshttps://doi.org/10.1007/3-540-34447-0_5openalex-snapshot
Central Neuropeptide Receptors Involved in Water Balance: Application to Apelin
inferred← citeshttps://doi.org/10.1007/5584_2020_567openalex-snapshot
Apelin Receptor Signaling During Mesoderm Development
inferred← citeshttps://doi.org/10.1007/978-2-8178-0466-8_6openalex-snapshot
Apelin Signaling in Retinal Angiogenesis
inferred← citeshttps://doi.org/10.1007/978-3-319-05392-9_147openalex-snapshot
Effect of Different Peptides
inferred← citeshttps://doi.org/10.1007/978-3-642-37078-6_144openalex-snapshot
Pathophysiology of Portal Hypertension
inferred← citeshttps://doi.org/10.1007/978-3-642-37393-0_144-1openalex-snapshot
Pathophysiology of Portal Hypertension
inferred← citeshttps://doi.org/10.1007/bf03165767openalex-snapshot
Expanding role for the apelin/APJ system in physiopathology
inferred← citeshttps://doi.org/10.1007/s00018-020-03461-7openalex-snapshot
Apelin/APJ system: an emerging therapeutic target for respiratory diseases
inferred← citeshttps://doi.org/10.1007/s00383-012-3210-7openalex-snapshot
Apelin is a marker of the progression of liver fibrosis and portal hypertension in patients with biliary atresia
inferred← citeshttps://doi.org/10.1007/s00404-022-06433-3openalex-snapshot
Apelin is associated with clinicopathological parameters and prognosis in breast cancer patients
inferred← citeshttps://doi.org/10.1007/s00441-009-0806-xopenalex-snapshot
Cordial connections: molecular ensembles and structures of adhering junctions connecting interstitial cells of cardiac valves in situ and in cell culture
inferred← citeshttps://doi.org/10.1007/s00726-010-0555-xopenalex-snapshot
Apelin suppresses apoptosis of human vascular smooth muscle cells via APJ/PI3-K/Akt signaling pathways
inferred← citeshttps://doi.org/10.1007/s00726-015-2020-3openalex-snapshot
Apelin attenuates the osteoblastic differentiation of aortic valve interstitial cells via the ERK and PI3-K/Akt pathways
inferred← citeshttps://doi.org/10.1007/s00784-015-1544-yopenalex-snapshot
Is there an association between obstructive sleep apnea syndrome and periodontal inflammation?
inferred← citeshttps://doi.org/10.1007/s10495-006-0489-7openalex-snapshot
Apelin suppresses apoptosis of human osteoblasts
inferred← citeshttps://doi.org/10.1007/s10522-023-10016-3openalex-snapshot
Signaling mechanisms underlying lymphatic vessel dysfunction in skin aging and possible anti-aging strategies
inferred← citeshttps://doi.org/10.1007/s10557-005-6900-8openalex-snapshot
Rethinking the Renin-Angiotensin System and Its Role in Cardiovascular Regulation
inferred← citeshttps://doi.org/10.1007/s10557-026-07913-3openalex-snapshot
The Apelin-APJ Axis in Heart Failure: Mechanistic Insights, Clinical Evidence, and Translational Challenges
inferred← citeshttps://doi.org/10.1007/s10735-004-1247-1openalex-snapshot
Distribution of apelin, the endogenous ligand of the APJ receptor, in the lizard Podarcis sicula
inferred← citeshttps://doi.org/10.1007/s10735-007-9135-0openalex-snapshot
Immunohistochemical localization of apelin in human normal breast and breast carcinoma
inferred← citeshttps://doi.org/10.1007/s10735-024-10279-1openalex-snapshot
Protective effect of Apelin-13 on oxygen and glucose deprivation induced-damage in retinal ganglion cells cultured in vitro
inferred← citeshttps://doi.org/10.1007/s10741-015-9475-xopenalex-snapshot
Effects of apelin on the cardiovascular system
inferred← citeshttps://doi.org/10.1007/s10856-019-6306-yopenalex-snapshot
An injectable thermosensitive hydrogel for sustained release of apelin-13 to enhance flap survival in rat random skin flap
inferred← citeshttps://doi.org/10.1007/s10989-013-9374-8openalex-snapshot
Apelin-13 Inhibits Apoptosis of Cortical Neurons Following Brain Ischemic Reperfusion Injury in a Transient Model of Focal Cerebral Ischemia
inferred← citeshttps://doi.org/10.1007/s10989-017-9638-9openalex-snapshot
Effect of Intracerebroventricular Administration of Apelin-13 on the Hypothalamus–Pituitary–Thyroid Axis and Peripheral Uncoupling Proteins
inferred← citeshttps://doi.org/10.1007/s10989-021-10173-4openalex-snapshot
Apelin 13 Improves Anxiety and Cognition Via Hippocampal Increases BDNF Expression and Reduction Cell Death in Neonatal Alcohol Exposed Rats
inferred← citeshttps://doi.org/10.1007/s11010-019-03581-0openalex-snapshot
Apelin promotes hepatic fibrosis through ERK signaling in LX-2 cells
inferred← citeshttps://doi.org/10.1007/s11033-014-3552-4openalex-snapshot
Apelin/APJ system: a promising therapy target for hypertension
inferred← citeshttps://doi.org/10.1007/s11033-023-08911-6openalex-snapshot
Protective effect of apelin-13 on ventilator-induced acute lung injury
inferred← citeshttps://doi.org/10.1007/s11064-014-1469-xopenalex-snapshot
Apelin-13 Attenuates Traumatic Brain Injury-Induced Damage by Suppressing Autophagy
inferred← citeshttps://doi.org/10.1007/s11064-016-1878-0openalex-snapshot
Apelin-13 Protects PC12 Cells from Corticosterone-Induced Apoptosis Through PI3K and ERKs Activation
inferred← citeshttps://doi.org/10.1007/s11064-016-1948-3openalex-snapshot
Apelin-13 Impaires Acquisition but Not Consolidation or Expression of Contextual Fear in Rats
inferred← citeshttps://doi.org/10.1007/s11626-025-01092-5openalex-snapshot
Co-cultured adipocytes alter the expression of genes involved in extracellular matrix remodeling and metabolic adaptation in muscle cells
inferred← citeshttps://doi.org/10.1007/s11690-011-0292-7openalex-snapshot
Effets métaboliques de l’apeline sur le tissu adipeux humain
inferred← citeshttps://doi.org/10.1007/s11845-021-02914-7openalex-snapshot
Serum Elabela level is related to endoscopic activity index in patients with active ulcerative colitis
inferred← citeshttps://doi.org/10.1007/s12020-011-9507-9openalex-snapshot
Apelin, diabetes, and obesity
inferred← citeshttps://doi.org/10.1007/s12031-012-9808-3openalex-snapshot
Apelin-13 Protects the Brain Against Ischemic Reperfusion Injury and Cerebral Edema in a Transient Model of Focal Cerebral Ischemia
inferred← citeshttps://doi.org/10.1007/s12170-011-0210-4openalex-snapshot
Update on the Role of Adipokines in Atherosclerosis and Cardiovascular Diseases
inferred← citeshttps://doi.org/10.1007/s12265-025-10612-3openalex-snapshot
Mesenchymal Stem Cell-based Apelin Gene Therapy Improves Pulmonary Artery Remodeling in Monocrotaline-induced Pulmonary Hypertension Through PI3K/AKT/eNOS and ERK1/2 Signaling Pathways
inferred← citeshttps://doi.org/10.1007/s13679-015-0174-7openalex-snapshot
Novel Mediators of Adipose Tissue and Muscle Crosstalk
inferred← citeshttps://doi.org/10.1007/s43032-021-00709-wopenalex-snapshot
Blood Circulating Levels of Adipokines in Polycystic Ovary Syndrome Patients: A Systematic Review and Meta-analysis
inferred← citeshttps://doi.org/10.1016/b978-0-12-803592-4.00006-7openalex-snapshot
Food Intake and Its Control by Signaling Molecules
inferred← citeshttps://doi.org/10.1016/b978-012369442-3/50111-2openalex-snapshot
Apelin: Discovery, Distribution, and Physiological Role
inferred← citeshttps://doi.org/10.1016/j.ab.2013.07.006openalex-snapshot
Pyroglutamyl apelin-13 identified as the major apelin isoform in human plasma
inferred← citeshttps://doi.org/10.1016/j.advms.2014.11.001openalex-snapshot
The effects of apelin treatment on a rat model of type 2 diabetes
inferred← citeshttps://doi.org/10.1016/j.ajpath.2011.08.024openalex-snapshot
Apelin Attenuates UVB-Induced Edema and Inflammation by Promoting Vessel Function
inferred← citeshttps://doi.org/10.1016/j.ando.2010.03.004openalex-snapshot
Participation de l’apéline à la régulation de l’équilibre hydrique, de l’homéostasie glucidique et des fonctions cardiovasculaires
inferred← citeshttps://doi.org/10.1016/j.bbadis.2016.11.007openalex-snapshot
Targeting the apelin pathway as a novel therapeutic approach for cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.bbagen.2017.05.017openalex-snapshot
Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands
inferred← citeshttps://doi.org/10.1016/j.bbrc.2004.10.042openalex-snapshot
Apelin is a novel angiogenic factor in retinal endothelial cells
inferred← citeshttps://doi.org/10.1016/j.bbrc.2007.04.017openalex-snapshot
Direct effects of apelin on cardiomyocyte contractility and electrophysiology
inferred← citeshttps://doi.org/10.1016/j.bbrc.2010.03.151openalex-snapshot
The fate of the internalized apelin receptor is determined by different isoforms of apelin mediating differential interaction with β-arrestin
inferred← citeshttps://doi.org/10.1016/j.bbrc.2023.01.068openalex-snapshot
Apelin expression is downregulated in T cells in a murine model of chronic colitis
inferred← citeshttps://doi.org/10.1016/j.bcp.2007.12.015openalex-snapshot
The apelin–APJ system in heart failure
inferred← citeshttps://doi.org/10.1016/j.bcp.2018.01.011openalex-snapshot
Adipokine apelin ameliorates chronic colitis in Il-10−/− mice by promoting intestinal lymphatic functions
inferred← citeshttps://doi.org/10.1016/j.beem.2004.08.002openalex-snapshot
Receptors for gut peptides
inferred← citeshttps://doi.org/10.1016/j.biopha.2016.09.048openalex-snapshot
Anticonvulsant and neuroprotective effects of apelin-13 on pentylenetetrazole-induced seizures in male rats
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119847openalex-snapshot
The apelin/APJ signaling axis in ocular neurovascular disorders: Molecular mechanisms and therapeutic strategies for angiogenesis and neurodegeneration
inferred← citeshttps://doi.org/10.1016/j.bmc.2014.04.001openalex-snapshot
Identifying structural determinants of potency for analogs of apelin-13: Integration of C-terminal truncation with structure–activity
inferred← citeshttps://doi.org/10.1016/j.bmc.2016.06.018openalex-snapshot
Discovery of a novel small molecule agonist scaffold for the APJ receptor
inferred← citeshttps://doi.org/10.1016/j.bmc.2019.115237openalex-snapshot
Identification of potent pyrazole based APELIN receptor (APJ) agonists
inferred← citeshttps://doi.org/10.1016/j.brainres.2019.146334openalex-snapshot
Apelin-36 mitigates MPTP/MPP+-induced neurotoxicity: Involvement of α-synuclein and endoplasmic reticulum stress
inferred← citeshttps://doi.org/10.1016/j.brainres.2019.146493openalex-snapshot
Apelin-36 mediates neuroprotective effects by regulating oxidative stress, autophagy and apoptosis in MPTP-induced Parkinson’s disease model mice
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2012.06.003openalex-snapshot
Centrally administered apelin-13 induces depression-like behavior in mice
inferred← citeshttps://doi.org/10.1016/j.brainresbull.2017.01.005openalex-snapshot
Amelioration of apelin-13 in chronic normobaric hypoxia-induced anxiety-like behavior is associated with an inhibition of NF-κB in the hippocampus
inferred← citeshttps://doi.org/10.1016/j.cardfail.2007.04.002openalex-snapshot
The 212A Variant of the APJ Receptor Gene for the Endogenous Inotrope Apelin is Associated With Slower Heart Failure Progression in Idiopathic Dilated Cardiomyopathy
inferred← citeshttps://doi.org/10.1016/j.cardfail.2010.02.002openalex-snapshot
Apelin Antagonizes Myocardial Impairment in Sepsis
inferred← citeshttps://doi.org/10.1016/j.cardfail.2010.02.004openalex-snapshot
Myocardial Apelin Production is Reduced in Humans With Left Ventricular Systolic Dysfunction
inferred← citeshttps://doi.org/10.1016/j.cardfail.2015.03.007openalex-snapshot
The Emerging Potential of the Apelin-APJ System in Heart Failure
inferred← citeshttps://doi.org/10.1016/j.cardiores.2004.08.018openalex-snapshot
The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
inferred← citeshttps://doi.org/10.1016/j.cardiores.2007.02.002openalex-snapshot
Apelin modulates aortic vascular tone via endothelial nitric oxide synthase phosphorylation pathway in diabetic mice
inferred← citeshttps://doi.org/10.1016/j.cca.2019.09.011openalex-snapshot
Role of apelin/APJ system in hypothalamic-pituitary axis
inferred← citeshttps://doi.org/10.1016/j.cellsig.2004.09.018openalex-snapshot
Apelin signalling: a promising pathway from cloning to pharmacology
inferred← citeshttps://doi.org/10.1016/j.cellsig.2017.08.003openalex-snapshot
Apelin protects against liver X receptor-mediated steatosis through AMPK and PPARα in human and mouse hepatocytes
inferred← citeshttps://doi.org/10.1016/j.cyto.2011.06.007openalex-snapshot
Apelin, vaspin, visfatin and adiponectin in large for gestational age infants with insulin resistance
inferred← citeshttps://doi.org/10.1016/j.ddmod.2012.06.003openalex-snapshot
G-protein-coupled receptors and pulmonary arterial hypertension (PAH)
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.01.011openalex-snapshot
Apelin and Its Receptor Control Heart Field Formation during Zebrafish Gastrulation
inferred← citeshttps://doi.org/10.1016/j.devcel.2007.01.012openalex-snapshot
The G Protein-Coupled Receptor Agtrl1b Regulates Early Development of Myocardial Progenitors
inferred← citeshttps://doi.org/10.1016/j.domaniend.2025.106976openalex-snapshot
Effects of experimentally induced LH surge on local regulation of apelin/APJ in follicle during ovulation and corpus luteum formation in the cow
inferred← citeshttps://doi.org/10.1016/j.drudis.2006.10.011openalex-snapshot
Therapeutic potential of interfering with apelin signalling
inferred← citeshttps://doi.org/10.1016/j.drudis.2022.05.004openalex-snapshot
APJ/apelin: A promising target for the treatment of retinopathy of prematurity
inferred← citeshttps://doi.org/10.1016/j.ejheart.2005.10.007openalex-snapshot
Plasma Concentrations of the Novel Peptide Apelin are Decreased in Patients with Chronic Heart Failure
inferred← citeshttps://doi.org/10.1016/j.ejheart.2008.06.002openalex-snapshot
The Role of Apelin in Cardiovascular Function and Heart Failure
inferred← citeshttps://doi.org/10.1016/j.ejim.2011.08.009openalex-snapshot
Traditional and novel cardiovascular risk factors in non-functioning adrenal adenomas
inferred← citeshttps://doi.org/10.1016/j.ejogrb.2014.02.022openalex-snapshot
Apelin levels in relation with hormonal and metabolic profile in patients with polycystic ovary syndrome
inferred← citeshttps://doi.org/10.1016/j.ejogrb.2024.03.034openalex-snapshot
Relationship between serum apelin, visfatin levels, and body composition in Polycystic Ovary Syndrome patients
inferred← citeshttps://doi.org/10.1016/j.ejphar.2015.05.017openalex-snapshot
Apelin receptors: From signaling to antidiabetic strategy
inferred← citeshttps://doi.org/10.1016/j.ejphar.2016.08.036openalex-snapshot
Apelin-36 is protective against N-methyl-D-aspartic-acid-induced retinal ganglion cell death in the mice
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177302openalex-snapshot
Advances in the therapeutic potentials of ligands of the apelin receptor APJ
inferred← citeshttps://doi.org/10.1016/j.euroneuro.2016.01.007openalex-snapshot
Apelin-13 exerts antidepressant-like and recognition memory improving activities in stressed rats
inferred← citeshttps://doi.org/10.1016/j.gene.2025.149591openalex-snapshot
Insights into the function and research status of membrane protein APJ
inferred← citeshttps://doi.org/10.1016/j.ijsu.2015.06.072openalex-snapshot
Apelin attenuates postburn sepsis via a phosphatidylinositol 3-kinase/protein kinase B dependent mechanism: A randomized animal study
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.108822openalex-snapshot
Apelin/APJ system in inflammation
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.109991openalex-snapshot
Apelin-13, a regulator of autophagy, apoptosis and inflammation in multifaceted bone protection
inferred← citeshttps://doi.org/10.1016/j.jacbts.2017.12.002openalex-snapshot
Designer Approaches for G Protein–Coupled Receptor Modulation for Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/j.jacc.2006.03.061openalex-snapshot
Utility of Amino-Terminal Pro-Brain Natriuretic Peptide, Galectin-3, and Apelin for the Evaluation of Patients With Acute Heart Failure
inferred← citeshttps://doi.org/10.1016/j.jacc.2008.06.013openalex-snapshot
Vascular Effects of Apelin In Vivo in Man
inferred← citeshttps://doi.org/10.1016/j.jhep.2008.09.019openalex-snapshot
Apelin signaling modulates splanchnic angiogenesis and portosystemic collateral vessel formation in rats with portal hypertension
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2007.06.006openalex-snapshot
Role of adipocytokines in obesity-associated insulin resistance
inferred← citeshttps://doi.org/10.1016/j.jphs.2016.12.002openalex-snapshot
Apelin protects against NMDA-induced retinal neuronal death via an APJ receptor by activating Akt and ERK1/2, and suppressing TNF-α expression in mice
inferred← citeshttps://doi.org/10.1016/j.jsxm.2021.02.004openalex-snapshot
Apelin-13 Protects Corpus Cavernosum Against Fibrosis Induced by High-Fat Diet in an MMP-Dependent Mechanism
inferred← citeshttps://doi.org/10.1016/j.lfs.2019.03.047openalex-snapshot
Apelin-36 exerts the cytoprotective effect against MPP+-induced cytotoxicity in SH-SY5Y cells through PI3K/Akt/mTOR autophagy pathway
inferred← citeshttps://doi.org/10.1016/j.mce.2007.07.008openalex-snapshot
Cloning and activation of the bullfrog apelin receptor: Gi/o coupling and high affinity for [Pro1]apelin-13
inferred← citeshttps://doi.org/10.1016/j.mce.2014.08.009openalex-snapshot
Molecular and physiological evidences for the role in appetite regulation of apelin and its receptor APJ in Ya-fish (Schizothorax prenanti)
inferred← citeshttps://doi.org/10.1016/j.mce.2016.07.040openalex-snapshot
Agonist-induced internalization and desensitization of the apelin receptor
inferred← citeshttps://doi.org/10.1016/j.mefs.2018.04.003openalex-snapshot
Serum adipokine (apelin) in lean and obese polycystic ovary syndrome patients before and after metformin treatment
inferred← citeshttps://doi.org/10.1016/j.metabol.2010.05.008openalex-snapshot
Serum levels of vaspin, obestatin, and apelin-36 in patients with nonalcoholic fatty liver disease
inferred← citeshttps://doi.org/10.1016/j.neuint.2013.09.017openalex-snapshot
Apelin-36, a potent peptide, protects against ischemic brain injury by activating the PI3K/Akt pathway
inferred← citeshttps://doi.org/10.1016/j.neulet.2016.06.046openalex-snapshot
The neuroprotective effect of apelin-13 in a mouse model of intracerebral hemorrhage
inferred← citeshttps://doi.org/10.1016/j.neulet.2022.136518openalex-snapshot
Apelin-13 Facilitates Lordosis Behavior Following Infusions to the Ventromedial Hypothalamus or Preoptic Area in Ovariectomized, Estrogen-Primed Rats
inferred← citeshttps://doi.org/10.1016/j.neuroscience.2024.12.025openalex-snapshot
Effects and mechanisms of Apelin in treating central nervous system diseases
inferred← citeshttps://doi.org/10.1016/j.npep.2016.08.001openalex-snapshot
Induction of antinociceptive tolerance to the chronic intrathecal administration of apelin-13 in rat
inferred← citeshttps://doi.org/10.1016/j.npep.2016.12.001openalex-snapshot
Peripheral apelin-13 administration inhibits gastrointestinal motor functions in rats: The role of cholecystokinin through CCK1 receptor-mediated pathway
inferred← citeshttps://doi.org/10.1016/j.npep.2019.101959openalex-snapshot
Apelin attenuates depressive-like behavior and neuroinflammation in rats co-treated with chronic stress and lipopolysaccharide
inferred← citeshttps://doi.org/10.1016/j.npep.2021.102130openalex-snapshot
Apelin-13 attenuates spatial memory impairment by anti-oxidative, anti-apoptosis, and anti-inflammatory mechanism against ethanol neurotoxicity in the neonatal rat hippocampus
inferred← citeshttps://doi.org/10.1016/j.npep.2021.102131openalex-snapshot
Neuroprotective gain of Apelin/APJ system
inferred← citeshttps://doi.org/10.1016/j.npep.2023.102382openalex-snapshot
The regulatory effects of the apelin/APJ system on depression: A prospective therapeutic target
inferred← citeshttps://doi.org/10.1016/j.numecd.2008.12.008openalex-snapshot
Effect of diet-induced weight loss on plasma apelin and cytokine levels in individuals with the metabolic syndrome
inferred← citeshttps://doi.org/10.1016/j.oraloncology.2011.12.015openalex-snapshot
Hypoxia-induced up-regulation of apelin is associated with a poor prognosis in oral squamous cell carcinoma patients
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2005.05.011openalex-snapshot
ACE2: A novel therapeutic target for cardiovascular diseases
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2017.09.013openalex-snapshot
Load-dependent effects of apelin on murine cardiomyocytes
inferred← citeshttps://doi.org/10.1016/j.peptides.2006.10.005openalex-snapshot
Apelin stimulates proliferation and suppresses apoptosis of mouse osteoblastic cell line MC3T3-E1 via JNK and PI3-K/Akt signaling pathways
inferred← citeshttps://doi.org/10.1016/j.peptides.2007.07.016openalex-snapshot
Apelin activates l-arginine/nitric oxide synthase/nitric oxide pathway in rat aortas
inferred← citeshttps://doi.org/10.1016/j.peptides.2009.02.011openalex-snapshot
Supraspinal administration of apelin-13 induces antinociception via the opioid receptor in mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2009.04.020openalex-snapshot
Apelin in goldfish (Carassius auratus): Cloning, distribution and role in appetite regulation
inferred← citeshttps://doi.org/10.1016/j.peptides.2010.08.021openalex-snapshot
The presence of the peptides apelin, ghrelin and nesfatin-1 in the human breast milk, and the lowering of their levels in patients with gestational diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.peptides.2010.09.006openalex-snapshot
Intracerebroventricular administration of apelin-13 inhibits distal colonic transit in mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.01.023openalex-snapshot
Effect of centrally administered apelin-13 on gastric emptying and gastrointestinal transit in mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.10.001openalex-snapshot
Apelin-13 passes through the ADMA-damaged endothelial barrier and acts on vascular smooth muscle cells
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.10.010openalex-snapshot
The apelinergic system in the developing lung: Expression and signaling
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.11.011openalex-snapshot
Central apelin-13 inhibits food intake via the CRF receptor in mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.12.005openalex-snapshot
Central and peripheral apelin receptor distribution in the mouse: Species differences with rat
inferred← citeshttps://doi.org/10.1016/j.peptides.2011.12.015openalex-snapshot
Apelin supports primary rat retinal Müller cells under chemical hypoxia and glucose deprivation
inferred← citeshttps://doi.org/10.1016/j.peptides.2012.03.005openalex-snapshot
Maternal hypertension induces tissue-specific modulations of the apelinergic system in the fetoplacental unit in rat
inferred← citeshttps://doi.org/10.1016/j.peptides.2012.06.007openalex-snapshot
Supraspinal antinociceptive effect of apelin-13 in a mouse visceral pain model
inferred← citeshttps://doi.org/10.1016/j.peptides.2012.07.012openalex-snapshot
Neuroprotection of apelin and its signaling pathway
inferred← citeshttps://doi.org/10.1016/j.peptides.2012.08.004openalex-snapshot
In vivo, ex vivo, and in vitro studies on apelin's effect on myocardial glucose uptake
inferred← citeshttps://doi.org/10.1016/j.peptides.2013.03.024openalex-snapshot
Regulation of feeding behavior, gastrointestinal function and fluid homeostasis by apelin
inferred← citeshttps://doi.org/10.1016/j.peptides.2013.05.013openalex-snapshot
The apelinergic system: Sexual dimorphism and tissue-specific modulations by obesity and insulin resistance in female mice
inferred← citeshttps://doi.org/10.1016/j.peptides.2014.10.003openalex-snapshot
The role of apelin-13 in novel object recognition memory
inferred← citeshttps://doi.org/10.1016/j.peptides.2014.11.011openalex-snapshot
Apelin's effects on young rat gastrointestinal tract maturation
inferred← citeshttps://doi.org/10.1016/j.peptides.2017.05.007openalex-snapshot
The evidence of apelin has the bidirectional effects on feeding regulation in Siberian sturgeon ( Acipenser baerii )
inferred← citeshttps://doi.org/10.1016/j.peptides.2019.170102openalex-snapshot
Anxiolytic impact of Apelin-13 in a rat model of Alzheimer's disease: Involvement of glucocorticoid receptor and FKBP5
inferred← citeshttps://doi.org/10.1016/j.peptides.2020.170350openalex-snapshot
Apelin inhibits an endothelium-derived hyperpolarizing factor-like pathway in rat cerebral arteries
inferred← citeshttps://doi.org/10.1016/j.peptides.2021.170697openalex-snapshot
Apelin pathway in cardiovascular, kidney, and metabolic diseases: Therapeutic role of apelin analogs and apelin receptor agonists
inferred← citeshttps://doi.org/10.1016/j.pharmr.2026.100130openalex-snapshot
International Union of Basic and Clinical Pharmacology. CXXI. Apelin receptor pharmacology in the human cardiovascular system and emerging clinical applications
inferred← citeshttps://doi.org/10.1016/j.pharmthera.2005.04.001openalex-snapshot
Emerging roles of apelin in biology and medicine
inferred← citeshttps://doi.org/10.1016/j.placenta.2010.06.001openalex-snapshot
Maternal Apelin Physiology during Rat Pregnancy: The Role of the Placenta
inferred← citeshttps://doi.org/10.1016/j.placenta.2016.01.006openalex-snapshot
Maternal obesity alters the apelinergic system at the feto-maternal interface
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2018.10.005openalex-snapshot
Protective role of Apelin-13 on amyloid β25–35-induced memory deficit; Involvement of autophagy and apoptosis process
inferred← citeshttps://doi.org/10.1016/j.regpep.2003.11.002openalex-snapshot
Immunocytochemical localization of the endogenous vasoactive peptide apelin to human vascular and endocardial endothelial cells
inferred← citeshttps://doi.org/10.1016/j.regpep.2004.10.019openalex-snapshot
Immunocytochemical localisation of the apelin receptor, APJ, to human cardiomyocytes, vascular smooth muscle and endothelial cells
inferred← citeshttps://doi.org/10.1016/j.regpep.2005.01.013openalex-snapshot
Apelin cells in the rat stomach
inferred← citeshttps://doi.org/10.1016/j.regpep.2006.02.004openalex-snapshot
Apelin and its receptor are expressed in human osteoblasts
inferred← citeshttps://doi.org/10.1016/j.regpep.2007.02.002openalex-snapshot
Increased colonic apelin production in rodents with experimental colitis and in humans with IBD
inferred← citeshttps://doi.org/10.1016/j.regpep.2010.03.005openalex-snapshot
Apelin is a novel islet peptide
inferred← citeshttps://doi.org/10.1016/j.regpep.2011.12.002openalex-snapshot
Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs
inferred← citeshttps://doi.org/10.1016/j.rmed.2012.10.026openalex-snapshot
Serum apelin-12 level is elevated in schoolchildren with atopic asthma
inferred← citeshttps://doi.org/10.1016/j.surg.2015.01.011openalex-snapshot
Apelin inhibits the activation of the nucleotide-binding domain and the leucine-rich, repeat-containing family, pyrin-containing 3 (NLRP3) inflammasome and ameliorates insulin resistance in severely burned rats
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2021.06.011openalex-snapshot
Reproductive roles of novel adipokines apelin, visfatin, and irisin in farm animals
inferred← citeshttps://doi.org/10.1016/j.theriogenology.2022.12.013openalex-snapshot
Expression and localization of apelin and apelin receptor (APJ) in buffalo ovarian follicles and corpus luteum and the in-vitro effect of apelin on steroidogenesis and survival of granulosa cells
inferred← citeshttps://doi.org/10.1016/j.tice.2019.01.003openalex-snapshot
Apelin receptor (Aplnr) signaling promotes fibroblast migration
inferred← citeshttps://doi.org/10.1016/j.tice.2019.101318openalex-snapshot
The effect of experimental varicocele on the apelin and APJ expressions in rat testis tissue
inferred← citeshttps://doi.org/10.1016/j.tips.2006.02.006openalex-snapshot
Unravelling the roles of the apelin system: prospective therapeutic applications in heart failure and obesity
inferred← citeshttps://doi.org/10.1016/j.tips.2015.06.002openalex-snapshot
Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system
inferred← citeshttps://doi.org/10.1016/j.virol.2003.08.026openalex-snapshot
The N-terminal domain of APJ, a CNS-based coreceptor for HIV-1, is essential for its receptor function and coreceptor activity
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.06.028openalex-snapshot
Xapelin and Xmsr are required for cardiovascular development in Xenopus laevis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.03.004openalex-snapshot
Paracrine and autocrine mechanisms of apelin signaling govern embryonic and tumor angiogenesis
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.08.035openalex-snapshot
Dynamics of apelin receptor/G protein coupling in living cells
inferred← citeshttps://doi.org/10.1016/j.ygcen.2006.12.013openalex-snapshot
Molecular evolution of neuropeptide receptors with regard to maintaining high affinity to their authentic ligands
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2006.07.004openalex-snapshot
Down-regulation of cardiac apelin system in hypertrophied and failing hearts: Possible role of angiotensin II–angiotensin type 1 receptor system
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2009.12.011openalex-snapshot
Modulation of canine cardiac sodium current by Apelin
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.07.002openalex-snapshot
Apelin administration ameliorates high fat diet-induced cardiac hypertrophy and contractile dysfunction
inferred← citeshttps://doi.org/10.1016/s0006-291x(03)01424-4openalex-snapshot
Circulating and cardiac levels of apelin, the novel ligand of the orphan receptor APJ, in patients with heart failure
inferred← citeshttps://doi.org/10.1016/s0014-2999(03)01821-1openalex-snapshot
Venous dilator effect of apelin, an endogenous peptide ligand for the orphan APJ receptor, in conscious rats
inferred← citeshttps://doi.org/10.1016/s0042-6822(02)00021-1openalex-snapshot
Cell–cell fusion and internalization of the CNS-based, HIV-1 co-receptor, APJ
inferred← citeshttps://doi.org/10.1016/s0042-6822(03)00185-5openalex-snapshot
Binding of ALX40-4C to APJ, a CNS-based receptor, inhibits its utilization as a co-receptor by HIV-1
inferred← citeshttps://doi.org/10.1016/s0079-6123(08)00443-3openalex-snapshot
Opposite potentiality of hypothalamic coexpressed neuropeptides, apelin and vasopressin in maintaining body-fluid homeostasis
inferred← citeshttps://doi.org/10.1016/s0165-6147(02)00007-xopenalex-snapshot
Emerging roles for orphan G-protein-coupled receptors in the cardiovascular system
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