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Pancreatic Exocrine Duct Cells Give Rise to Insulin-Producing β Cells during Embryogenesis but Not after Birth
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/aja.1000120304openalex-snapshot
Studies on the pancreas of the guinea pig
inferredcites →https://doi.org/10.1006/dbio.2002.0597openalex-snapshot
Efficient Recombination in Diverse Tissues by a Tamoxifen-Inducible Form of Cre: A Tool for Temporally Regulated Gene Activation/Inactivation in the Mouse
inferredcites →https://doi.org/10.1006/jmbi.1998.2307openalex-snapshot
Inducible site-specific recombination in the brain 1 1Edited by M. Yaniv
inferredcites →https://doi.org/10.1007/bf00400600openalex-snapshot
Duct- to islet-cell differentiation and islet growth in the pancreas of duct-ligated adult rats
inferredcites →https://doi.org/10.1007/bf00403301openalex-snapshot
Beta-cell growth in adolescent and adult rats treated with streptozotocin during the neonatal period
inferredcites →https://doi.org/10.1007/s00125-003-1287-1openalex-snapshot
Combined gastrin and epidermal growth factor treatment induces islet regeneration and restores normoglycaemia in C57Bl6/J mice treated with alloxan
inferredcites →https://doi.org/10.1016/0012-1606(72)90083-8openalex-snapshot
An ultrastructural analysis of the developing embryonic pancreas
inferredcites →https://doi.org/10.1016/0963-6897(95)00020-xopenalex-snapshot
In Vivo Cell Transformation: Neogenesis of Beta Cells from Pancreatic Ductal Cells
inferredcites →https://doi.org/10.1016/j.cell.2007.12.015openalex-snapshot
β Cells Can Be Generated from Endogenous Progenitors in Injured Adult Mouse Pancreas
inferredcites →https://doi.org/10.1016/j.devcel.2007.04.011openalex-snapshot
Growth and Regeneration of Adult β Cells Does Not Involve Specialized Progenitors
inferredcites →https://doi.org/10.1016/j.devcel.2007.06.001openalex-snapshot
A Multipotent Progenitor Domain Guides Pancreatic Organogenesis
inferredcites →https://doi.org/10.1016/j.modgep.2006.11.001openalex-snapshot
Snail2, a mediator of epithelial-mesenchymal transitions, expressed in progenitor cells of the developing endocrine pancreas
inferredcites →https://doi.org/10.1016/j.modgep.2007.09.006openalex-snapshot
Expression of HNF-4α (MODY1), HNF-1β (MODY5), and HNF-1α (MODY3) proteins in the developing mouse pancreas
inferredcites →https://doi.org/10.1016/j.ydbio.2008.07.034openalex-snapshot
A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation
inferredcites →https://doi.org/10.1016/s0940-9602(03)80025-0openalex-snapshot
Centroacinar and intercalated duct cells as potential precursors of pancreatic endocrine cells in rats treated with streptozotocin
inferredcites →https://doi.org/10.1038/371606a0openalex-snapshot
Insulin-promoter-factor 1 is required for pancreas development in mice
inferredcites →https://doi.org/10.1038/5007openalex-snapshot
Generalized lacZ expression with the ROSA26 Cre reporter strain
inferredcites →https://doi.org/10.1038/nature02520openalex-snapshot
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
inferredcites →https://doi.org/10.1038/nature07314openalex-snapshot
In vivo reprogramming of adult pancreatic exocrine cells to β-cells
inferredcites →https://doi.org/10.1038/ng959openalex-snapshot
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors
inferredcites →https://doi.org/10.1053/j.gastro.2005.12.005openalex-snapshot
The Transcription Factor Hepatocyte Nuclear Factor-6 Controls the Development of Pancreatic Ducts in the Mouse
inferredcites →https://doi.org/10.1053/j.gastro.2009.01.047openalex-snapshot
Notch Signaling as Gatekeeper of Rat Acinar-to-β-Cell Conversion in Vitro
inferredcites →https://doi.org/10.1053/j.gastro.2009.03.022openalex-snapshot
Notch Signaling: Where Pancreatic Cancer and Differentiation Meet?
inferredcites →https://doi.org/10.1073/pnas.0405776102openalex-snapshot
Lack of TCF2/vHNF1 in mice leads to pancreas agenesis
inferredcites →https://doi.org/10.1073/pnas.0507567102openalex-snapshot
Lineage tracing and characterization of insulin-secreting cells generated from adult pancreatic acinar cells
inferredcites →https://doi.org/10.1073/pnas.0605248104openalex-snapshot
β cell transdifferentiation does not contribute to preneoplastic/metaplastic ductal lesions of the pancreas by genetic lineage tracing in vivo
inferredcites →https://doi.org/10.1073/pnas.0704054104openalex-snapshot
Sox9 coordinates a transcriptional network in pancreatic progenitor cells
inferredcites →https://doi.org/10.1073/pnas.0805803105openalex-snapshot
Carbonic anhydrase II-positive pancreatic cells are progenitors for both endocrine and exocrine pancreas after birth
inferredcites →https://doi.org/10.1073/pnas.241349398openalex-snapshot
A transcription factor regulatory circuit in differentiated pancreatic cells
inferredcites →https://doi.org/10.1093/hmg/ddg355openalex-snapshot
Hnf6 and Tcf2 (MODY5) are linked in a gene network operating in a precursor cell domain of the embryonic pancreas
inferredcites →https://doi.org/10.1093/hmg/ddl161openalex-snapshot
Severe pancreas hypoplasia and multicystic renal dysplasia in two human fetuses carrying novel HNF1β/MODY5 mutations
inferredcites →https://doi.org/10.1097/00006676-199207000-00002openalex-snapshot
Ultrastructure of the Rat Pancreas after Experimental Duct Ligation. II. Duct and Stromal Cell Proliferation, Differentiation, and Deletion
inferredcites →https://doi.org/10.1101/gr.749203openalex-snapshot
A Highly Efficient Recombineering-Based Method for Generating Conditional Knockout Mutations
inferredcites →https://doi.org/10.1128/mcb.21.9.3234-3243.2001openalex-snapshot
Hepatic Nuclear Factor 1-α Directs Nucleosomal Hyperacetylation to Its Tissue-Specific Transcriptional Targets
inferredcites →https://doi.org/10.1172/jci29988openalex-snapshot
Preexisting pancreatic acinar cells contribute to acinar cell, but not islet β cell, regeneration
inferredcites →https://doi.org/10.1172/jci32959openalex-snapshot
Recovery from diabetes in mice by β cell regeneration
inferredcites →https://doi.org/10.1210/en.138.4.1736openalex-snapshot
Apoptosis Participates in the Remodeling of the Endocrine Pancreas in the Neonatal Rat
inferredcites →https://doi.org/10.1210/endo.141.6.7567openalex-snapshot
Perspective: Postnatal Pancreatic β Cell Growth
inferredcites →https://doi.org/10.1210/jc.2004-0761openalex-snapshot
Combination Therapy with Epidermal Growth Factor and Gastrin Induces Neogenesis of Human Islet β-Cells from Pancreatic Duct Cells and an Increase in Functional β-Cell Mass
inferredcites →https://doi.org/10.1242/dev.118.1.33openalex-snapshot
Epithelial cell proliferation and islet neogenesis in IFN-g transgenic mice
inferredcites →https://doi.org/10.1242/dev.127.11.2317openalex-snapshot
Adult insulin- and glucagon-producing cells differentiate from two independent cell lineages
inferredcites →https://doi.org/10.1242/dev.129.10.2447openalex-snapshot
Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors
inferredcites →https://doi.org/10.1369/jhc.2008.950675openalex-snapshot
Generation and Characterization of Ptf1a Antiserum and Localization of Ptf1a in Relation to Nkx6.1 and Pdx1 During the Earliest Stages of Mouse Pancreas Development
inferredcites →https://doi.org/10.2337/db06-0832openalex-snapshot
Patients With Chronic Pancreatitis Have Islet Progenitor Cells in Their Ducts, but Reversal of Overt Diabetes in NOD Mice by Anti-CD3 Shows No Evidence for Islet Regeneration
inferredcites →https://doi.org/10.2337/diab.42.12.1715openalex-snapshot
A Second Pathway for Regeneration of Adult Exocrine and Endocrine Pancreas: A Possible Recapitulation of Embryonic Development
inferredcites →https://doi.org/10.2337/diabetes.49.8.1341openalex-snapshot
Linear correlation between beta-cell mass and body weight throughout the lifespan in Lewis rats: role of beta-cell hyperplasia and hypertrophy.
inferredcites →https://doi.org/10.2337/diabetes.54.9.2596openalex-snapshot
Combination Therapy With Epidermal Growth Factor and Gastrin Increases β-Cell Mass and Reverses Hyperglycemia in Diabetic NOD Mice
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4789208openalex-extracted
Unlocking Regenerative Potential: Beta-Cell Neogenesis and Novel Myokines Involved in Adaptation to Insulin Resistance in Mice
inferred← citeshttps://doi.org/10.1002/ar.22420openalex-snapshot
Whole‐Mount Imaging Demonstrates Hypervascularity of the Pancreatic Ducts and Other Pancreatic Structures
inferred← citeshttps://doi.org/10.1002/bies.201800119openalex-snapshot
Evidence for a Neogenic Niche at the Periphery of Pancreatic Islets
inferred← citeshttps://doi.org/10.1002/cphy.c230008openalex-snapshot
Pancreatic Crosstalk in the Disease Setting: Understanding the Impact of Exocrine Disease on Endocrine Function
inferred← citeshttps://doi.org/10.1002/dvdy.22556openalex-snapshot
Essential role of clusterin in pancreas regeneration
inferred← citeshttps://doi.org/10.1002/dvdy.22561openalex-snapshot
Facultative stem cells in liver and pancreas: Fact and fancy
inferred← citeshttps://doi.org/10.1002/dvdy.22584openalex-snapshot
Pancreas organogenesis: From bud to plexus to gland
inferred← citeshttps://doi.org/10.1002/dvdy.70063openalex-snapshot
Streptozotocin induced hyperglycemia in the axolotl
inferred← citeshttps://doi.org/10.1002/hep.26254openalex-snapshot
Canonical Notch2 signaling determines biliary cell fates of embryonic hepatoblasts and adult hepatocytes independent of Hes1
inferred← citeshttps://doi.org/10.1002/hep.27078openalex-snapshot
The biliary epithelium gives rise to liver progenitor cells
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2024.tb00294.xopenalex-snapshot
Pancreatic Crosstalk in the Disease Setting: Understanding the Impact of Exocrine Disease on Endocrine Function
inferred← citeshttps://doi.org/10.1002/jhbp.246openalex-snapshot
Molecular mechanism of intraductal papillary mucinous neoplasm and intraductal papillary mucinous neoplasm-derived pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1002/jmor.20806openalex-snapshot
Development of the duct system during exocrine pancreas differentiation in the grass snake Natrix natrix (Lepidosauria, Serpentes)
inferred← citeshttps://doi.org/10.1002/jmor.20921openalex-snapshot
Development of endocrine pancreatic islets in embryos of the grass snake Natrix natrix (Lepidosauria, Serpentes)
inferred← citeshttps://doi.org/10.1002/jmor.21083openalex-snapshot
Development of pancreatic acini in embryos of the grass snake Natrix natrix (Lepidosauria, Serpentes)
inferred← citeshttps://doi.org/10.1002/path.5629openalex-snapshot
Insights into the etiology and physiopathology of MODY5 / HNF1B pancreatic phenotype with a mouse model of the human disease
inferred← citeshttps://doi.org/10.1002/path.5759openalex-snapshot
Brg1 is required to maintain colorectal cancer stem cells
inferred← citeshttps://doi.org/10.1002/path.6139openalex-snapshot
Simultaneous activation of Kras–Akt and Notch pathways induces extrahepatic biliary cancer via the mTORC1 pathway
inferred← citeshttps://doi.org/10.1002/sctm.19-0231openalex-snapshot
SOX9+/PTF1A+ Cells Define the Tip Progenitor Cells of the Human Fetal Pancreas of the Second Trimester
inferred← citeshttps://doi.org/10.1002/stem.1828openalex-snapshot
Concise Reviews: In Vitro-Produced Pancreas Organogenesis Models in Three Dimensions: Self-Organization From Few Stem Cells or Progenitors
inferred← citeshttps://doi.org/10.1002/stem.482openalex-snapshot
Pancreatic β-Cell Neogenesis by Direct Conversion from Mature α-Cells
inferred← citeshttps://doi.org/10.1002/wdev.99openalex-snapshot
Notch signaling in the pancreas: patterning and cell fate specification
inferred← citeshttps://doi.org/10.1007/5584_2022_756openalex-snapshot
Direct Reprogramming of Somatic Cells into Induced β-Cells: An Overview
inferred← citeshttps://doi.org/10.1007/978-1-0716-2014-4_13openalex-snapshot
Murine Models for Lineage Tracing Cancer Initiating Cells
inferred← citeshttps://doi.org/10.1007/978-1-4614-7696-2_20openalex-snapshot
Progenitors of Islet Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-0793-9_6openalex-snapshot
Diabetes in Children and Adolescents
inferred← citeshttps://doi.org/10.1007/978-1-4939-6631-8_4-2openalex-snapshot
Developmental Molecular Biology of the Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-4939-7193-0_4openalex-snapshot
Developmental Molecular Biology of the Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-4939-8961-4_5openalex-snapshot
Genetic Lineage Tracing of Biliary Epithelial Cells
inferred← citeshttps://doi.org/10.1007/978-1-4939-9631-5_6openalex-snapshot
Isolation and Characterization of Colony-Forming Progenitor Cells from Adult Pancreas
inferred← citeshttps://doi.org/10.1007/978-1-61779-225-0_14openalex-snapshot
Reprogramming Towards Pancreatic β-Cells
inferred← citeshttps://doi.org/10.1007/978-1-61779-225-0_15openalex-snapshot
Pancreatic Plasticity and Reprogramming: Novel Directions Towards Disease Therapy
inferred← citeshttps://doi.org/10.1007/978-1-62703-068-7_20openalex-snapshot
Lineage Tracing of Pancreatic Stem Cells and Beta Cell Regeneration
inferred← citeshttps://doi.org/10.1007/978-1-62703-098-4_9openalex-snapshot
Pancreatic Regeneration in the Face of Diabetes
inferred← citeshttps://doi.org/10.1007/978-1-62703-200-1_14openalex-snapshot
Advances in Lentiviral Vector-based Cell Therapy with Mesenchymal Stem Cells
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_2openalex-snapshot
Development of the Pancreatic Ducts and Their Contribution to Organogenesis
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_3openalex-snapshot
β-Cell Heterogeneity and Plasticity
inferred← citeshttps://doi.org/10.1007/978-3-031-62232-8_4openalex-snapshot
β-Cell Regeneration Is Driven by Pancreatic Plasticity
inferred← citeshttps://doi.org/10.1007/978-3-319-21705-5_6openalex-snapshot
The Elusive Pancreatic Stem Cell
inferred← citeshttps://doi.org/10.1007/978-3-319-55687-1_1openalex-snapshot
Stem Cell Transplantation in Diabetes Mellitus Type I and Type II
inferred← citeshttps://doi.org/10.1007/978-3-319-57153-9_10openalex-snapshot
Engineering Organoid Systems to Model Health and Disease
inferred← citeshttps://doi.org/10.1007/978-3-319-90695-9_9openalex-snapshot
Regenerative Medicine for Diabetes Treatment: New β-Cell Sources
inferred← citeshttps://doi.org/10.1007/978-81-322-2110-4_14openalex-snapshot
Overview of Pancreatic Replacement of β-Cells from Various Cell Sources
inferred← citeshttps://doi.org/10.1007/978-94-007-6686-0_36openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/978-94-007-6884-0_36-2openalex-snapshot
Regulation of Pancreatic Islet Formation
inferred← citeshttps://doi.org/10.1007/s00018-013-1510-2openalex-snapshot
Transcriptional control of mammalian pancreas organogenesis
inferred← citeshttps://doi.org/10.1007/s00125-010-1963-xopenalex-snapshot
The stress of starvation: glucocorticoid restraint of beta cell development
inferred← citeshttps://doi.org/10.1007/s00125-011-2153-1openalex-snapshot
Epidermal growth factor (EGF)-receptor signalling is needed for murine beta cell mass expansion in response to high-fat diet and pregnancy but not after pancreatic duct ligation
inferred← citeshttps://doi.org/10.1007/s00125-014-3468-5openalex-snapshot
Ins1 Cre knock-in mice for beta cell-specific gene recombination
inferred← citeshttps://doi.org/10.1007/s00125-016-4023-3openalex-snapshot
A combination of cytokines EGF and CNTF protects the functional beta cell mass in mice with short-term hyperglycaemia
inferred← citeshttps://doi.org/10.1007/s00125-022-05662-0openalex-snapshot
Spatial and transcriptional heterogeneity of pancreatic beta cell neogenesis revealed by a time-resolved reporter system
inferred← citeshttps://doi.org/10.1007/s00441-010-1028-yopenalex-snapshot
Clonal and territorial development of the pancreas as revealed by eGFP-labelled mouse chimeras
inferred← citeshttps://doi.org/10.1007/s00534-010-0303-3openalex-snapshot
Regenerative medicine for insulin deficiency: creation of pancreatic islets and bioartificial pancreas
inferred← citeshttps://doi.org/10.1007/s00534-010-0307-zopenalex-snapshot
Genetic lineage tracing, a powerful tool to investigate the embryonic organogenesis and adult organ maintenance of the pancreas
inferred← citeshttps://doi.org/10.1007/s00534-012-0545-3openalex-snapshot
Basics and applications of stem cells in the pancreas
inferred← citeshttps://doi.org/10.1007/s00592-011-0306-9openalex-snapshot
Severely fibrotic pancreases from young patients with chronic pancreatitis: evidence for a ductal origin of islet neogenesis
inferred← citeshttps://doi.org/10.1007/s11626-012-9555-3openalex-snapshot
Induction of mouse pancreatic ductal differentiation, an in vitro assay
inferred← citeshttps://doi.org/10.1007/s11626-021-00580-8openalex-snapshot
A new shortened protocol to obtain islet-like cells from hESC-derived ductal cells
inferred← citeshttps://doi.org/10.1007/s11892-011-0218-7openalex-snapshot
Potential Pathways to Restore β-Cell Mass: Pluripotent Stem Cells, Reprogramming, and Endogenous Regeneration
inferred← citeshttps://doi.org/10.1007/s11892-012-0301-8openalex-snapshot
Understanding Pancreas Development for β-Cell Repair and Replacement Therapies
inferred← citeshttps://doi.org/10.1007/s11892-013-0400-1openalex-snapshot
Making β Cells from Adult Cells Within the Pancreas
inferred← citeshttps://doi.org/10.1007/s11892-016-0729-3openalex-snapshot
New Insights into Diabetes Cell Therapy
inferred← citeshttps://doi.org/10.1007/s11892-019-1176-8openalex-snapshot
How, When, and Where Do Human β-Cells Regenerate?
inferred← citeshttps://doi.org/10.1007/s11892-019-1261-zopenalex-snapshot
Organoids from the Human Fetal and Adult Pancreas
inferred← citeshttps://doi.org/10.1007/s12015-011-9333-8openalex-snapshot
Pancreatic Stem Cells: From Possible to Probable
inferred← citeshttps://doi.org/10.1007/s12015-012-9350-2openalex-snapshot
Ontogenesis of Hepatic and Pancreatic Stem Cells
inferred← citeshttps://doi.org/10.1007/s12015-025-10859-yopenalex-snapshot
Pancreatic Ductal Cell Heterogeneity: Insights into the Potential for β-Cell Regeneration in Diabetes
inferred← citeshttps://doi.org/10.1007/s13340-024-00774-xopenalex-snapshot
Differentiation, reduction, and proliferation of pancreatic β-cells and their regulatory factors
inferred← citeshttps://doi.org/10.1007/s13402-022-00664-xopenalex-snapshot
Molecular signaling in pancreatic ductal metaplasia: emerging biomarkers for detection and intervention of early pancreatic cancer
inferred← citeshttps://doi.org/10.1007/s13410-026-01626-xopenalex-snapshot
Clinical presentation, biochemical profile, and imaging characteristics of patients with genetically confirmed maturity-onset diabetes of the young (MODY) type 5: Our experience and systematic review
inferred← citeshttps://doi.org/10.1007/s40139-015-0068-0openalex-snapshot
Direct Reprogramming for Pancreatic Beta-Cells Using Key Developmental Genes
inferred← citeshttps://doi.org/10.1016/b978-0-12-385233-5.00001-5openalex-snapshot
Transcriptional Control of Acinar Development and Homeostasis
inferred← citeshttps://doi.org/10.1016/b978-0-12-386456-7.04901-7openalex-snapshot
Normal Pancreatic Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-405945-0.00031-4openalex-snapshot
Pancreas Development and Regeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-416012-5.00002-5openalex-snapshot
Pancreatic Stem Cells
inferred← citeshttps://doi.org/10.1016/b978-0-12-416021-7.00006-7openalex-snapshot
From Pancreas Morphogenesis to β-Cell Regeneration
inferred← citeshttps://doi.org/10.1016/b978-0-12-800563-7.00008-7openalex-snapshot
Gene Therapy for Diabetes
inferred← citeshttps://doi.org/10.1016/b978-0-12-814831-0.00026-9openalex-snapshot
Pancreas progenitors
inferred← citeshttps://doi.org/10.1016/b978-0-12-814831-0.00029-4openalex-snapshot
Ductal cell reprograming to insulin-producing cells as a potential beta cell replacement source for islet auto-transplant recipients
inferred← citeshttps://doi.org/10.1016/b978-0-443-15289-4.00013-5openalex-snapshot
Pancreatic Stem Cells and Regenerative Medicine of Endocrine Pancreas
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2016.10.005openalex-snapshot
Zebrafish Pancreas Development and Regeneration
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.02.009openalex-snapshot
Recapitulating and Deciphering Human Pancreas Development From Human Pluripotent Stem Cells in a Dish
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2018.12.005openalex-snapshot
Pancreas organogenesis: The interplay between surrounding microenvironment(s) and epithelium-intrinsic factors
inferred← citeshttps://doi.org/10.1016/bs.ctdb.2020.10.006openalex-snapshot
Pancreas morphogenesis: Branching in and then out
inferred← citeshttps://doi.org/10.1016/j.acthis.2017.08.004openalex-snapshot
Mesenchymal cells are required for epithelial duct cell-to-beta cell maturation and function in an injured adult pancreas in the rat
inferred← citeshttps://doi.org/10.1016/j.arr.2013.01.001openalex-snapshot
Generating insulin-producing cells for diabetic therapy: Existing strategies and new development
inferred← citeshttps://doi.org/10.1016/j.arr.2022.101674openalex-snapshot
The pancreatic β-cell in ageing: Implications in age-related diabetes
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2016.04.011openalex-snapshot
AGC1/2, the mitochondrial aspartate-glutamate carriers
inferred← citeshttps://doi.org/10.1016/j.bbcan.2022.188698openalex-snapshot
Ductal metaplasia in pancreas
inferred← citeshttps://doi.org/10.1016/j.bcp.2020.114216openalex-snapshot
Antidiabetic drug therapy alleviates type 1 diabetes in mice by promoting pancreatic α-cell transdifferentiation
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115019openalex-snapshot
GABA and insulin but not nicotinamide augment α- to β-cell transdifferentiation in insulin-deficient diabetic mice
inferred← citeshttps://doi.org/10.1016/j.beem.2015.10.001openalex-snapshot
Reprogramming of human exocrine pancreas cells to beta cells
inferred← citeshttps://doi.org/10.1016/j.biocel.2010.07.006openalex-snapshot
Pancreatic acinar cell: New insights into the control of secretion
inferred← citeshttps://doi.org/10.1016/j.ccr.2012.10.025openalex-snapshot
Identification of Sox9-Dependent Acinar-to-Ductal Reprogramming as the Principal Mechanism for Initiation of Pancreatic Ductal Adenocarcinoma
inferred← citeshttps://doi.org/10.1016/j.ceb.2017.11.014openalex-snapshot
Phenotypic plasticity in the pancreas: new triggers, new players
inferred← citeshttps://doi.org/10.1016/j.cell.2018.12.003openalex-snapshot
A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets
inferred← citeshttps://doi.org/10.1016/j.celrep.2012.10.016openalex-snapshot
Planar Cell Polarity Controls Pancreatic Beta Cell Differentiation and Glucose Homeostasis
inferred← citeshttps://doi.org/10.1016/j.celrep.2016.03.036openalex-snapshot
Proinflammatory Cytokines Induce Endocrine Differentiation in Pancreatic Ductal Cells via STAT3-Dependent NGN3 Activation
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.110377openalex-snapshot
Adult pancreatic islet endocrine cells emerge as fetal hormone-expressing cells
inferred← citeshttps://doi.org/10.1016/j.cmet.2009.12.005openalex-snapshot
Ductal Origin Hypothesis of Pancreatic Regeneration under Attack
inferred← citeshttps://doi.org/10.1016/j.cmet.2012.04.018openalex-snapshot
Adenosine Signaling Promotes Regeneration of Pancreatic β Cells In Vivo
inferred← citeshttps://doi.org/10.1016/j.cmet.2013.06.011openalex-snapshot
Pancreas-Specific Cre Driver Lines and Considerations for Their Prudent Use
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.08.007openalex-snapshot
Pancreatic β Cell Regeneration as a Possible Therapy for Diabetes
inferred← citeshttps://doi.org/10.1016/j.cmet.2022.11.009openalex-snapshot
Single-cell transcriptomic and spatial landscapes of the developing human pancreas
inferred← citeshttps://doi.org/10.1016/j.cmet.2026.07.023openalex-snapshot
A single-cell multi-omic atlas of the human pancreas reveals potential for cellular plasticity across development, health, and disease
inferred← citeshttps://doi.org/10.1016/j.cophys.2019.10.019openalex-snapshot
Pancreatic β cell regeneration: to β or not to β
inferred← citeshttps://doi.org/10.1016/j.cophys.2019.11.009openalex-snapshot
Insights on β-cell regeneration from the zebrafish shoal: from generation of cells to functional integration
inferred← citeshttps://doi.org/10.1016/j.cub.2013.05.037openalex-snapshot
Metabolic Regulation of Cellular Plasticity in the Pancreas
inferred← citeshttps://doi.org/10.1016/j.devcel.2010.02.005openalex-snapshot
Cellular Plasticity within the Pancreas— Lessons Learned from Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2010.05.015openalex-snapshot
Nkx6 Transcription Factors and Ptf1a Function as Antagonistic Lineage Determinants in Multipotent Pancreatic Progenitors
inferred← citeshttps://doi.org/10.1016/j.devcel.2013.03.016openalex-snapshot
Gene Regulatory Networks Governing Pancreas Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2013.05.018openalex-snapshot
Adult Duct-Lining Cells Can Reprogram into β-like Cells Able to Counter Repeated Cycles of Toxin-Induced Diabetes
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.05.024openalex-snapshot
Postnatal Exocrine Pancreas Growth by Cellular Hypertrophy Correlates with a Shorter Lifespan in Mammals
inferred← citeshttps://doi.org/10.1016/j.devcel.2018.06.028openalex-snapshot
Defining Lineage Potential and Fate Behavior of Precursors during Pancreas Development
inferred← citeshttps://doi.org/10.1016/j.devcel.2020.01.015openalex-snapshot
Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
inferred← citeshttps://doi.org/10.1016/j.devcel.2022.07.014openalex-snapshot
Pancreas agenesis mutations disrupt a lead enhancer controlling a developmental enhancer cluster
inferred← citeshttps://doi.org/10.1016/j.devcel.2023.08.023openalex-snapshot
Single-cell epigenome analysis identifies molecular events controlling direct conversion of human fibroblasts to pancreatic ductal-like cells
inferred← citeshttps://doi.org/10.1016/j.diff.2015.10.008openalex-snapshot
Islet Neogenesis Associated Protein (INGAP) induces the differentiation of an adult human pancreatic ductal cell line into insulin-expressing cells through stepwise activation of key transcription factors for embryonic beta cell development
inferred← citeshttps://doi.org/10.1016/j.gendis.2014.09.004openalex-snapshot
The versatile functions of Sox9 in development, stem cells, and human diseases
inferred← citeshttps://doi.org/10.1016/j.isci.2024.110332openalex-snapshot
MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2019.06.005openalex-snapshot
Pancreatic Ductal Deletion of Hnf1b Disrupts Exocrine Homeostasis, Leads to Pancreatitis, and Facilitates Tumorigenesis
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.11.010openalex-snapshot
On the Origin of Pancreatic Cancer: Molecular Tumor Subtypes in Perspective of Exocrine Cell Plasticity
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2025.101639openalex-snapshot
Loss of Brg1 and Pten in Pancreatic Ductal Cells Forms Intraductal Tubulopapillary Neoplasm via the YAP/TAZ Pathway
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2026.101743openalex-snapshot
The Stathmin 1-lineage Contributes to Acinar Regeneration but Not to Neoplasia Upon Oncogenic Kras Expression
inferred← citeshttps://doi.org/10.1016/j.mce.2014.03.004openalex-snapshot
Bone marrow mesenchymal stem cells promote the repair of islets from diabetic mice through paracrine actions
inferred← citeshttps://doi.org/10.1016/j.mce.2016.11.008openalex-snapshot
Pancreatic β-cell regeneration: Facultative or dedicated progenitors?
inferred← citeshttps://doi.org/10.1016/j.mce.2021.111459openalex-snapshot
Stem/progenitor cells in normal physiology and disease of the pancreas
inferred← citeshttps://doi.org/10.1016/j.mod.2020.103634openalex-snapshot
β-Cell specific transcription factors in the context of diabetes mellitus and β-cell regeneration
inferred← citeshttps://doi.org/10.1016/j.molmet.2014.01.010openalex-snapshot
Islet cell plasticity and regeneration
inferred← citeshttps://doi.org/10.1016/j.molmet.2022.101467openalex-snapshot
Physically interacting beta-delta pairs in the regenerating pancreas revealed by single-cell sequencing
inferred← citeshttps://doi.org/10.1016/j.proghi.2013.09.001openalex-snapshot
The ductal origin of structural and functional heterogeneity between pancreatic islets
inferred← citeshttps://doi.org/10.1016/j.scr.2015.11.015openalex-snapshot
Cells with surface expression of CD133highCD71low are enriched for tripotent colony-forming progenitor cells in the adult murine pancreas
inferred← citeshttps://doi.org/10.1016/j.semcdb.2010.07.007openalex-snapshot
Pancreatic beta-cells: From generation to regeneration
inferred← citeshttps://doi.org/10.1016/j.semcdb.2012.06.005openalex-snapshot
Lineage determinants in early endocrine development
inferred← citeshttps://doi.org/10.1016/j.semcdb.2012.06.008openalex-snapshot
Exocrine ontogenies: On the development of pancreatic acinar, ductal and centroacinar cells
inferred← citeshttps://doi.org/10.1016/j.semcdb.2015.08.013openalex-snapshot
Pax4 acts as a key player in pancreas development and plasticity
inferred← citeshttps://doi.org/10.1016/j.semcdb.2017.01.005openalex-snapshot
The molecular and morphogenetic basis of pancreas organogenesis
inferred← citeshttps://doi.org/10.1016/j.semcdb.2018.08.008openalex-snapshot
Mesodermal induction of pancreatic fate commitment
inferred← citeshttps://doi.org/10.1016/j.stem.2014.11.001openalex-snapshot
Plasticity and Dedifferentiation within the Pancreas: Development, Homeostasis, and Disease
inferred← citeshttps://doi.org/10.1016/j.stem.2016.05.010openalex-snapshot
De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data
inferred← citeshttps://doi.org/10.1016/j.stem.2017.11.020openalex-snapshot
Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes
inferred← citeshttps://doi.org/10.1016/j.stem.2021.07.004openalex-snapshot
Continuous clonal labeling reveals uniform progenitor potential in the adult exocrine pancreas
inferred← citeshttps://doi.org/10.1016/j.stem.2021.08.003openalex-snapshot
Ductal Ngn3-expressing progenitors contribute to adult β cell neogenesis in the pancreas
inferred← citeshttps://doi.org/10.1016/j.stem.2021.10.005openalex-snapshot
New evidence for adult beta cell neogenesis
inferred← citeshttps://doi.org/10.1016/j.stem.2023.03.003openalex-snapshot
Matters arising: Insufficient evidence that pancreatic β cells are derived from adult ductal Neurog3-expressing progenitors
inferred← citeshttps://doi.org/10.1016/j.stemcr.2015.02.017openalex-snapshot
Efficient Generation of NKX6-1+ Pancreatic Progenitors from Multiple Human Pluripotent Stem Cell Lines
inferred← citeshttps://doi.org/10.1016/j.stemcr.2018.01.028openalex-snapshot
Heterogeneity of SOX9 and HNF1β in Pancreatic Ducts Is Dynamic
inferred← citeshttps://doi.org/10.1016/j.stemcr.2018.02.005openalex-snapshot
Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential
inferred← citeshttps://doi.org/10.1016/j.stemcr.2023.02.001openalex-snapshot
Methylcellulose colony assay and single-cell micro-manipulation reveal progenitor-like cells in adult human pancreatic ducts
inferred← citeshttps://doi.org/10.1016/j.tcb.2014.09.003openalex-snapshot
Plasticity within stem cell hierarchies in mammalian epithelia
inferred← citeshttps://doi.org/10.1016/j.tcb.2021.09.007openalex-snapshot
Harnessing orthogonal recombinases to decipher cell fate with enhanced precision
inferred← citeshttps://doi.org/10.1016/j.tem.2010.02.008openalex-snapshot
Emerging roles for the TGFβ family in pancreatic β-cell homeostasis
inferred← citeshttps://doi.org/10.1016/j.tem.2010.09.004openalex-snapshot
β-Cell regeneration: the pancreatic intrinsic faculty
inferred← citeshttps://doi.org/10.1016/j.tem.2018.10.002openalex-snapshot
Pancreatic Progenitors: There and Back Again
inferred← citeshttps://doi.org/10.1016/j.tem.2024.12.008openalex-snapshot
Lineage tracing of pancreatic cells for mechanistic and therapeutic insights
inferred← citeshttps://doi.org/10.1016/j.trsl.2010.06.005openalex-snapshot
Stem cell approaches for the treatment of type 1 diabetes mellitus
inferred← citeshttps://doi.org/10.1016/j.trsl.2013.11.012openalex-snapshot
Adult tissue sources for new β cells
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.08.006openalex-snapshot
Ngn3+ endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.10.025openalex-snapshot
Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.11.010openalex-snapshot
Ongoing Notch signaling maintains phenotypic fidelity in the adult exocrine pancreas
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.04.002openalex-snapshot
Zebrafish sox9b is crucial for hepatopancreatic duct development and pancreatic endocrine cell regeneration
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.10.030openalex-snapshot
ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools
inferred← citeshttps://doi.org/10.1016/j.ydbio.2013.04.003openalex-snapshot
Smad signaling pathways regulate pancreatic endocrine development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2015.07.002openalex-snapshot
REST represses a subset of the pancreatic endocrine differentiation program
inferred← citeshttps://doi.org/10.1016/j.ydbio.2016.02.027openalex-snapshot
Centroacinar cells: At the center of pancreas regeneration
inferred← citeshttps://doi.org/10.1016/j.yexcr.2014.01.030openalex-snapshot
Thyroid hormones promote endocrine differentiation at expenses of exocrine tissue
inferred← citeshttps://doi.org/10.1016/j.ymthe.2018.02.014openalex-snapshot
Long-Term Correction of Diabetes in Mice by In Vivo Reprogramming of Pancreatic Ducts
inferred← citeshttps://doi.org/10.1016/s1155-1941(23)43263-5openalex-snapshot
10.1016/s1155-1941(23)43263-5
inferred← citeshttps://doi.org/10.1021/acsptsci.9b00048openalex-snapshot
Inventing Liraglutide, a Glucagon-Like Peptide-1 Analogue, for the Treatment of Diabetes and Obesity
inferred← citeshttps://doi.org/10.1038/cddis.2013.52openalex-snapshot
Neurogenin 3+ cells contribute to β-cell neogenesis and proliferation in injured adult mouse pancreas
inferred← citeshttps://doi.org/10.1038/labinvest.2013.113openalex-snapshot
Specific transduction and labeling of pancreatic ducts by targeted recombinant viral infusion into mouse pancreatic ducts
inferred← citeshttps://doi.org/10.1038/nbt.2747openalex-snapshot
Transient cytokine treatment induces acinar cell reprogramming and regenerates functional beta cell mass in diabetic mice
inferred← citeshttps://doi.org/10.1038/ncb2916openalex-snapshot
The chromatin regulator Brg1 suppresses formation of intraductal papillary mucinous neoplasm and pancreatic ductal adenocarcinoma
inferred← citeshttps://doi.org/10.1038/ncb3309openalex-snapshot
Stem cells versus plasticity in liver and pancreas regeneration
inferred← citeshttps://doi.org/10.1038/ng.722openalex-snapshot
Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine
inferred← citeshttps://doi.org/10.1038/nprot.2013.079openalex-snapshot
Isolation, culture and genetic manipulation of mouse pancreatic ductal cells
inferred← citeshttps://doi.org/10.1038/nrendo.2013.145openalex-snapshot
The use of stem cells for pancreatic regeneration in diabetes mellitus
inferred← citeshttps://doi.org/10.1038/nrgastro.2017.93openalex-snapshot
Regenerative medicine and cell-based approaches to restore pancreatic function
inferred← citeshttps://doi.org/10.1038/onc.2015.437openalex-snapshot
KrasG12D induces EGFR-MYC cross signaling in murine primary pancreatic ductal epithelial cells
inferred← citeshttps://doi.org/10.1038/onc.2015.441openalex-snapshot
p53 mutations cooperate with oncogenic Kras to promote adenocarcinoma from pancreatic ductal cells
inferred← citeshttps://doi.org/10.1038/s12276-021-00593-zopenalex-snapshot
Insulin-positive ductal cells do not migrate into preexisting islets during pregnancy
inferred← citeshttps://doi.org/10.1038/s41392-023-01707-xopenalex-snapshot
EZH2 inhibitors promote β-like cell regeneration in young and adult type 1 diabetes donors
inferred← citeshttps://doi.org/10.1038/s41392-024-02098-3openalex-snapshot
Pancreatic endocrine and exocrine signaling and crosstalk in physiological and pathological status
inferred← citeshttps://doi.org/10.1038/s41421-022-00485-0openalex-snapshot
Use of a dual genetic system to decipher exocrine cell fate conversions in the adult pancreas
inferred← citeshttps://doi.org/10.1038/s41467-017-00258-4openalex-snapshot
Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis
inferred← citeshttps://doi.org/10.1038/s41467-017-00561-0openalex-snapshot
Glycoprotein 2 is a specific cell surface marker of human pancreatic progenitors
inferred← citeshttps://doi.org/10.1038/s41467-017-00666-6openalex-snapshot
Endoderm Jagged induces liver and pancreas duct lineage in zebrafish
inferred← citeshttps://doi.org/10.1038/s41467-018-02942-5openalex-snapshot
Genome-wide meta-analysis identifies five new susceptibility loci for pancreatic cancer
inferred← citeshttps://doi.org/10.1038/s41467-021-23295-6openalex-snapshot
A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion
inferred← citeshttps://doi.org/10.1038/s41467-021-23673-0openalex-snapshot
Reinforcing one-carbon metabolism via folic acid/Folr1 promotes β-cell differentiation
inferred← citeshttps://doi.org/10.1038/s41574-018-0132-zopenalex-snapshot
Modelling the endocrine pancreas in health and disease
inferred← citeshttps://doi.org/10.1038/s41575-023-00775-2openalex-snapshot
Fetal liver development and implications for liver disease pathogenesis
inferred← citeshttps://doi.org/10.1038/s41575-025-01116-1openalex-snapshot
Advances in liver and pancreas organoids: how far we have come and where we go next
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