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Role of pyroptosis in cardiovascular diseases
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1 of the 99 references listed on this page is in the Retraction Watch database as retracted (export 2026-10-28): 10.3892/mmr.2013.1507 (notice 2017-09-20).
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1007/s00395-018-0692-zopenalex-snapshotCaspase-1 inhibition by VX-765 administered at reperfusion in P2Y12 receptor antagonist-treated rats provides long-term reduction in myocardial infarct size and preservation of ventricular function
inferredcites →https://doi.org/10.1016/j.bbrc.2017.09.006openalex-snapshotCholecalciterol cholesterol emulsion attenuates experimental autoimmune myocarditis in mice via inhibition of the pyroptosis signaling pathway
inferredcites →https://doi.org/10.1016/j.jaci.2017.11.040openalex-snapshotA functional splice variant associated with decreased asthma risk abolishes the ability of gasdermin B to induce epithelial cell pyroptosis
inferredcites →https://doi.org/10.1016/j.tox.2018.09.002openalex-snapshotAcrolein induces NLRP3 inflammasome-mediated pyroptosis and suppresses migration via ROS-dependent autophagy in vascular endothelial cells
inferredcites →https://doi.org/10.1038/mi.2016.73openalex-snapshotNeutrophil pyroptosis mediates pathology of P. aeruginosa lung infection in the absence of the NADPH oxidase NOX2
inferredcites →https://doi.org/10.1038/ni.1864openalex-snapshotThe AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses
inferredcites →https://doi.org/10.1038/onc.2014.96openalex-snapshotMolecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition
inferredcites →https://doi.org/10.1038/s41418-018-0106-7openalex-snapshotSingle-cell analysis of pyroptosis dynamics reveals conserved GSDMD-mediated subcellular events that precede plasma membrane rupture
inferredcites →https://doi.org/10.1073/pnas.0707370105openalex-snapshotAnthrax lethal toxin and Salmonella elicit the common cell death pathway of caspase-1-dependent pyroptosis via distinct mechanisms
inferredcites →https://doi.org/10.1093/cvr/cvt091openalex-snapshotThe NLRP3 inflammasome is up-regulated in cardiac fibroblasts and mediates myocardial ischaemia–reperfusion injury
inferredcites →https://doi.org/10.1111/ajt.14699openalex-snapshotVEGF mitigates histone-induced pyroptosis in the remote liver injury associated with renal allograft ischemia–reperfusion injury in rats
inferredcites →https://doi.org/10.1111/jpi.12449openalex-snapshotMelatonin prevents endothelial cell pyroptosis via regulation of long noncoding RNA MEG3/miR‐223/NLRP3 axis
inferredcites →https://doi.org/10.1155/2017/9743280openalex-snapshotNLRP3 Inflammasome Activation‐Mediated Pyroptosis Aggravates Myocardial Ischemia/Reperfusion Injury in Diabetic Rats
inferredcites →https://doi.org/10.1159/000488183openalex-snapshotPioglitazone Confers Neuroprotection Against Ischemia-Induced Pyroptosis due to its Inhibitory Effects on HMGB-1/RAGE and Rac1/ROS Pathway by Activating PPAR-ɤ
inferredcites →https://doi.org/10.12659/msm.908529openalex-snapshotNF-κB-Gasdermin D (GSDMD) Axis Couples Oxidative Stress and NACHT, LRR and PYD Domains-Containing Protein 3 (NLRP3) Inflammasome-Mediated Cardiomyocyte Pyroptosis Following Myocardial Infarction
inferredcites →https://doi.org/10.3892/mmr.2013.1507openalex-snapshotCathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway
inferredcites →https://doi.org/10.3892/mmr.2017.7551openalex-snapshotCathepsin B inhibition attenuates cardiac dysfunction and remodeling following myocardial infarction by inhibiting the NLRP3 pathway
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4673402openalex-extractedShengxian Decoction Protects Against Obesity-Induced Cardiac Injuryin Rats by Regulating the Hk1/Nlrp3 Signalling Pathway
inferred← citeshttps://doi.org/10.1002/14651858.cd014741openalex-snapshotInterleukin-receptor antagonist and tumor necrosis factor inhibitors for the primary and secondary prevention of atherosclerotic cardiovascular diseases
inferred← citeshttps://doi.org/10.1002/14651858.cd014741.pub2openalex-snapshotInterleukin-receptor antagonist and tumour necrosis factor inhibitors for the primary and secondary prevention of atherosclerotic cardiovascular diseases
inferred← citeshttps://doi.org/10.1002/biof.1787openalex-snapshotMelatonin ameliorates trimethyltin chloride‐induced cardiotoxicity: The role of nuclear xenobiotic metabolism and Keap1‐Nrf2 / ARE axis‐mediated pyroptosis
inferred← citeshttps://doi.org/10.1002/ehf2.13814openalex-snapshotRETRACTED: Long Non-Coding RNA Sox2OT Promotes Coronary Microembolization-Induced Myocardial Injury by Mediating Pyroptosis
inferred← citeshttps://doi.org/10.1002/jat.4258openalex-snapshotPFOS facilitates liver inflammation and steatosis: An involvement of NLRP3 inflammasome‐mediated hepatocyte pyroptosis
inferred← citeshttps://doi.org/10.1002/jat.70061openalex-snapshotUnravelling the Potential Role of Nanoplastics and Microplastics‐Induced Toxicity in Freshwater Fish: Emerging Role of Programmed Cell Death Mechanisms
inferred← citeshttps://doi.org/10.1002/ptr.7191openalex-snapshotEmodin alleviates LPS ‐induced myocardial injury through inhibition of NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.08.007openalex-snapshotGasdermin D-mediated pyroptosis in myocardial ischemia and reperfusion injury: Cumulative evidence for future cardioprotective strategies
inferred← citeshttps://doi.org/10.1016/j.bbrc.2022.09.057openalex-snapshotTRIM16 exerts protective function on myocardial ischemia/reperfusion injury through reducing pyroptosis and inflammation via NLRP3 signaling
inferred← citeshttps://doi.org/10.1016/j.bcp.2021.114791openalex-snapshotVolume-activated chloride channels contribute to lipopolysaccharide plus nigericin–induced pyroptosis in bone marrow–derived macrophages
inferred← citeshttps://doi.org/10.1016/j.biopha.2022.113999openalex-snapshotResearch progress on pyroptosis-mediated immune-inflammatory response in ischemic stroke and the role of natural plant components as regulator of pyroptosis: A review
inferred← citeshttps://doi.org/10.1016/j.ejphar.2025.177816openalex-snapshotDCAAA mitigates neuroinflammation and microglial pyroptosis in spinal cord injury by inhibiting PI3K/AKT/NF-κB and NLRP3/caspase-1/GSDMD signaling
inferred← citeshttps://doi.org/10.1016/j.imbio.2021.152133openalex-snapshotLong non-coding RNA RP11-490M8.1 inhibits lipopolysaccharide-induced pyroptosis of human umbilical vein endothelial cells via the TLR4/NF-κB pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2020.107086openalex-snapshotPuerarin protects against myocardial ischemia/reperfusion injury by inhibiting inflammation and the NLRP3 inflammasome: The role of the SIRT1/NF-κB pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110219openalex-snapshotSevoflurane exerts protection against myocardial ischemia–reperfusion injury and pyroptosis through the circular RNA PAN3/microRNA-29b-3p/stromal cell-derived factor 4 axis
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.110423openalex-snapshotEleutheroside E from pre-treatment of Acanthopanax senticosus (Rupr.etMaxim.) Harms ameliorates high-altitude-induced heart injury by regulating NLRP3 inflammasome-mediated pyroptosis via NLRP3/caspase-1 pathway
inferred← citeshttps://doi.org/10.1016/j.intimp.2023.111454openalex-snapshotCaspase-3/gasdermin-E axis facilitates the progression of coronary artery calcification by inducing the release of high mobility group box protein 1
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.113428openalex-snapshotInterleukin-38 ameliorates myocardial Ischemia-Reperfusion injury via inhibition of NLRP3 inflammasome activation in fibroblasts through the IL-1R8/SYK axis
inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101497openalex-snapshotInnovative diabetes mellitus treatment strategies: Mesenchymal stem cell-based therapy and its impact on pro- and anti-inflammatory cytokines modulation
inferred← citeshttps://doi.org/10.1016/j.lfs.2025.124167openalex-snapshotYAP inactivated by NF-κB p65, can protect against colonic epithelial cell pyroptosis in ulcerative colitis via transcriptionally regulating NLRP3
inferred← citeshttps://doi.org/10.1016/j.numecd.2022.02.014openalex-snapshotSodium selenite and Se-enriched yeast supplementation in atherosclerotic patients: Effects on the expression of pyroptosis-related genes and oxidative stress status
inferred← citeshttps://doi.org/10.1016/j.tice.2026.103720openalex-snapshotColchicine attenuates diet-induced early aortic vascular remodeling in mice via modulation of inflammatory and cell death-associated pathways
inferred← citeshttps://doi.org/10.1021/acsami.1c17382openalex-snapshotDelivery of Ultrasmall Nanoparticles to the Cytosolic Compartment of Pyroptotic J774A.1 Macrophages via GSDMDNterm Membrane Pores
inferred← citeshttps://doi.org/10.1038/s41374-021-00635-0openalex-snapshotLncRNA XIST shuttled by adipose tissue-derived mesenchymal stem cell-derived extracellular vesicles suppresses myocardial pyroptosis in atrial fibrillation by disrupting miR-214-3p-mediated Arl2 inhibition
inferred← citeshttps://doi.org/10.1038/s41419-019-2021-3openalex-snapshotEndothelial cell pyroptosis plays an important role in Kawasaki disease via HMGB1/RAGE/cathespin B signaling pathway and NLRP3 inflammasome activation
inferred← citeshttps://doi.org/10.1038/s41598-024-70477-5openalex-snapshotInhibition of Caspase-1-dependent pyroptosis alleviates myocardial ischemia/reperfusion injury during cardiopulmonary bypass (CPB) in type 2 diabetic rats
inferred← citeshttps://doi.org/10.1080/21655979.2023.2253414openalex-snapshotExosomes derived from bone marrow mesenchymal stem cells regulate pyroptosis via the miR-143-3p/myeloid differentiation factor 88 axis to ameliorate intestinal ischemia-reperfusion injury
inferred← citeshttps://doi.org/10.1111/all.14907openalex-snapshotCaspases and therapeutic potential of caspase inhibitors in moderate–severe SARS‐CoV‐2 infection and long COVID
inferred← citeshttps://doi.org/10.1111/cas.15384openalex-snapshotThe HOXC‐AS2/miR‐876‐5p/HKDC1 axis regulates endometrial cancer progression in a high glucose‐related tumor microenvironment
inferred← citeshttps://doi.org/10.1111/jdi.14087openalex-snapshotIdentification and validation of voltage‐dependent anion channel 1‐related genes and immune cell infiltration in diabetic nephropathy
inferred← citeshttps://doi.org/10.1113/ep090685openalex-snapshotInhibition of the glycogen synthase kinase 3β–hypoxia‐inducible factor 1α pathway alleviates NLRP3‐mediated pyroptosis induced by high glucose in renal tubular epithelial cells
inferred← citeshttps://doi.org/10.1139/bcb-2020-0672openalex-snapshotCLEC5A knockdown protects against cardiac dysfunction after myocardial infarction by suppressing macrophage polarization, NLRP3 inflammasome activation, and pyroptosis
inferred← citeshttps://doi.org/10.1142/s0192415x24500198openalex-snapshotAstragaloside IV Alleviates Doxorubicin-Induced Cardiotoxicity by Inhibiting Cardiomyocyte Pyroptosis through the SIRT1/NLRP3 Pathway
inferred← citeshttps://doi.org/10.1155/2021/6966394openalex-snapshotRh‐CXCL‐12 Attenuates Neuronal Pyroptosis after Subarachnoid Hemorrhage in Rats via Regulating the CXCR4/NLRP1 Pathway
inferred← citeshttps://doi.org/10.1155/2022/4622520openalex-snapshotKDM3A Attenuates Myocardial Ischemic and Reperfusion Injury by Ameliorating Cardiac Microvascular Endothelial Cell Pyroptosis
inferred← citeshttps://doi.org/10.1155/mi/6298056openalex-snapshotPropofol and Salvianolic Acid a Synergistically Attenuate LPS‐Induced Myocardial Pyroptosis in Diabetic Mice via the SIRT1/HMGB1 Pathway
inferred← citeshttps://doi.org/10.1186/s12864-019-5743-9openalex-snapshotGene expression profiling analysis to investigate the role of remote ischemic postconditioning in ischemia-reperfusion injury in rats
inferred← citeshttps://doi.org/10.1186/s12868-022-00747-3openalex-snapshotMechanism of LSD1 in oxygen-glucose deprivation/reoxygenation-induced pyroptosis of retinal ganglion cells via the miR-21-5p/NLRP12 axis
inferred← citeshttps://doi.org/10.1186/s12876-026-04986-0openalex-snapshotDual GIP/GLP-1 receptor agonist tirzepatide ameliorates hepatic steatosis and inflammatory responses in a MASLD mouse model associated with the CCL2/CCR2 axis
inferred← citeshttps://doi.org/10.1186/s12974-021-02137-8openalex-snapshotRelevant mediators involved in and therapies targeting the inflammatory response induced by activation of the NLRP3 inflammasome in ischemic stroke
inferred← citeshttps://doi.org/10.1186/s13287-019-1522-4openalex-snapshotLncRNA KLF3-AS1 in human mesenchymal stem cell-derived exosomes ameliorates pyroptosis of cardiomyocytes and myocardial infarction through miR-138-5p/Sirt1 axis
inferred← citeshttps://doi.org/10.1186/s40001-023-01277-2openalex-snapshotDevelopment and validation of a kidney renal clear cell carcinoma prognostic model relying on pyroptosis-related LncRNAs-A multidimensional comprehensive bioinformatics exploration
inferred← citeshttps://doi.org/10.1186/s40001-024-01765-zopenalex-snapshotPreparation of VX765 sodium alginate nanogels and evaluation of their therapeutic effect via local injection on myocardial infarction in rats
inferred← citeshttps://doi.org/10.1536/ihj.21-571openalex-snapshotMelatonin Inhibits OGD/R-Induced H9c2 Cardiomyocyte Pyroptosis via Regulation of MT2/miR-155/FOXO3a/ARC Axis
inferred← citeshttps://doi.org/10.18632/aging.205631openalex-snapshotThe low expression of miR-155 promotes the expression of SHP2 by inhibiting the activation of the ERK1/2 pathway and improves cell pyroptosis induced by I/R in mice
inferred← citeshttps://doi.org/10.21037/atm-20-8196openalex-snapshotMelatonin alleviates lipopolysaccharide-induced myocardial injury by inhibiting inflammation and pyroptosis in cardiomyocytes
inferred← citeshttps://doi.org/10.21037/tcr-22-177openalex-snapshotIdentification of a pyroptosis related gene signature for predicting prognosis and estimating tumor immune microenvironment in bladder cancer
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1298963/v1openalex-snapshotExploring key genes and potential therapeutic and predictive targets between pyroptosis genes and adult extent of malignant glioma based on bioinformatics analysis
inferred← citeshttps://doi.org/10.21203/rs.3.rs-2722788/v1openalex-snapshotExploring potential diagnostic and therapeutic targets for glioma based on the prognostic model of differential expression of pyroxis-related genes
inferred← citeshttps://doi.org/10.21203/rs.3.rs-7562588/v1openalex-snapshotTirzepatide but not Semaglutide Ameliorates Hepatic Steatosis and Inflammatory Infiltration in a Mouse Model of MASLD via Inhibition of the CCL2/CCR2-PI3K-Akt Pathway
inferred← citeshttps://doi.org/10.2147/dddt.s379629openalex-snapshotBaicalin Alleviates Contrast-Induced Acute Kidney Injury Through ROS/NLRP3/Caspase-1/GSDMD Pathway-Mediated Proptosis in vitro
inferred← citeshttps://doi.org/10.2147/jir.s386470openalex-snapshotSodium Tanshinone IIA Sulfonate Inhibits Vascular Endothelial Cell Pyroptosis via the AMPK Signaling Pathway in Atherosclerosis
inferred← citeshttps://doi.org/10.2298/vsp241003015mopenalex-snapshotThe association of IL-1β, IL-1α, IL-6, and E-selectin with the diastolic dysfunction in patients with type 2 diabetes mellitus and preserved ejection fraction
inferred← citeshttps://doi.org/10.3389/fcvm.2021.693257openalex-snapshotmiR-200a-3p Attenuates Coronary Microembolization-Induced Myocardial Injury in Rats by Inhibiting TXNIP/NLRP3-Mediated Cardiomyocyte Pyroptosis
inferred← citeshttps://doi.org/10.3389/fcvm.2022.755619openalex-snapshotAdenosine A2a Receptor Regulates Autophagy Flux and Apoptosis to Alleviate Ischemia-Reperfusion Injury via the cAMP/PKA Signaling Pathway
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