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Versatile functions for IL-6 in metabolism and cancer
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.282.22.2131openalex-snapshot
Elevated C-Reactive Protein Levels in Overweight and Obese Adults
inferredcites →https://doi.org/10.1001/jama.286.3.327openalex-snapshot
C-Reactive Protein, Interleukin 6, and Risk of Developing Type 2 Diabetes Mellitus
inferredcites →https://doi.org/10.1002/eji.1830171008openalex-snapshot
High‐affinity binding sites for human 26‐kDa protein (interleukin 6, B cell stimulatory factor‐2, human hybridoma plasmacytoma growth factor, interferon‐β2), different from those of type I interferon (α,β), on lymphoblastoid cells
inferredcites →https://doi.org/10.1002/eji.1830240837openalex-snapshot
Soluble interleukin‐6 receptors released from T cell or granulocyte/macrophage cell lines and human peripheral blood mononuclear cells are generated through an alternative splicing mechanism
inferredcites →https://doi.org/10.1002/hep.24655openalex-snapshot
Glucocorticoids Increase Interleukin–6–Dependent Gene Induction by Interfering With the Expression of the Suppressor of Cytokine Signaling 3 Feedback Inhibitor
inferredcites →https://doi.org/10.1002/j.1460-2075.1986.tb04531.xopenalex-snapshot
Structure and expression of cDNA and genes for human interferon‐beta‐2, a distinct species inducible by growth‐stimulatory cytokines.
inferredcites →https://doi.org/10.1007/978-3-540-73259-4_7openalex-snapshot
Humanized Antihuman IL-6 Receptor Antibody, Tocilizumab
inferredcites →https://doi.org/10.1007/s00125-004-1403-xopenalex-snapshot
Interleukin-6 and tumor necrosis factor-? are not increased in patients with Type 2 diabetes: evidence that plasma interleukin-6 is related to fat mass and not insulin responsiveness
inferredcites →https://doi.org/10.1007/s00125-010-1865-yopenalex-snapshot
Interleukin-6-deficient mice develop hepatic inflammation and systemic insulin resistance
inferredcites →https://doi.org/10.1016/0092-8674(89)90438-8openalex-snapshot
Interleukin-6 triggers the association of its receptor with a possible signal transducer, gp130
inferredcites →https://doi.org/10.1016/0092-8674(94)90235-6openalex-snapshot
Molecular cloning of APRF, a novel IFN-stimulated gene factor 3 p91-related transcription factor involved in the gp130-mediated signaling pathway
inferredcites →https://doi.org/10.1016/1043-4666(92)90043-qopenalex-snapshot
Isolation of an mRNA encoding a soluble form of the human interleukin-6 receptor
inferredcites →https://doi.org/10.1016/j.bbamcr.2011.01.034openalex-snapshot
The pro- and anti-inflammatory properties of the cytokine interleukin-6
inferredcites →https://doi.org/10.1016/j.ccr.2009.01.001openalex-snapshot
IL-6 and Stat3 Are Required for Survival of Intestinal Epithelial Cells and Development of Colitis-Associated Cancer
inferredcites →https://doi.org/10.1016/j.ccr.2011.10.012openalex-snapshot
IL-6 Controls Leukemic Multipotent Progenitor Cell Fate and Contributes to Chronic Myelogenous Leukemia Development
inferredcites →https://doi.org/10.1016/j.cell.2009.12.052openalex-snapshot
Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression
inferredcites →https://doi.org/10.1016/j.cell.2010.09.043openalex-snapshot
DNA Damage-Mediated Induction of a Chemoresistant Niche
inferredcites →https://doi.org/10.1016/j.celrep.2013.07.023openalex-snapshot
Obesity Promotes Liver Carcinogenesis via Mcl-1 Stabilization Independent of IL-6Rα Signaling
inferredcites →https://doi.org/10.1016/j.cmet.2006.02.009openalex-snapshot
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production
inferredcites →https://doi.org/10.1016/j.cmet.2006.05.011openalex-snapshot
Oxidative metabolism and PGC-1β attenuate macrophage-mediated inflammation
inferredcites →https://doi.org/10.1016/j.cmet.2007.05.004openalex-snapshot
Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production
inferredcites →https://doi.org/10.1016/j.cmet.2007.11.011openalex-snapshot
Interleukin-6 Is an Essential Regulator of Satellite Cell-Mediated Skeletal Muscle Hypertrophy
inferredcites →https://doi.org/10.1016/j.cmet.2008.08.015openalex-snapshot
Ablation of CD11c-Positive Cells Normalizes Insulin Sensitivity in Obese Insulin Resistant Animals
inferredcites →https://doi.org/10.1016/j.cmet.2009.08.013openalex-snapshot
MyD88 Signaling in the CNS Is Required for Development of Fatty Acid-Induced Leptin Resistance and Diet-Induced Obesity
inferredcites →https://doi.org/10.1016/j.cmet.2010.06.011openalex-snapshot
Interleukin-6 Signaling in Liver-Parenchymal Cells Suppresses Hepatic Inflammation and Improves Systemic Insulin Action
inferredcites →https://doi.org/10.1016/j.cmet.2011.02.010openalex-snapshot
Adiponectin Enhances Insulin Sensitivity by Increasing Hepatic IRS-2 Expression via a Macrophage-Derived IL-6-Dependent Pathway
inferredcites →https://doi.org/10.1016/j.cmet.2011.11.013openalex-snapshot
Orchestration of Metabolism by Macrophages
inferredcites →https://doi.org/10.1016/j.cmet.2013.09.017openalex-snapshot
Adipose Natural Regulatory B Cells Negatively Control Adipose Tissue Inflammation
inferredcites →https://doi.org/10.1016/j.cmet.2014.05.005openalex-snapshot
Adipocyte Inflammation Is Essential for Healthy Adipose Tissue Expansion and Remodeling
inferredcites →https://doi.org/10.1016/j.cmet.2014.06.011openalex-snapshot
A Switch from White to Brown Fat Increases Energy Expenditure in Cancer-Associated Cachexia
inferredcites →https://doi.org/10.1016/j.cytogfr.2012.04.001openalex-snapshot
Plasticity and cross-talk of Interleukin 6-type cytokines
inferredcites →https://doi.org/10.1016/j.immuni.2004.07.020openalex-snapshot
TGF-β Suppresses Tumor Progression in Colon Cancer by Inhibition of IL-6 trans-Signaling
inferredcites →https://doi.org/10.1016/j.immuni.2010.05.007openalex-snapshot
Alternative Activation of Macrophages: Mechanism and Functions
inferredcites →https://doi.org/10.1016/j.immuni.2014.06.008openalex-snapshot
Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
inferredcites →https://doi.org/10.1016/j.smim.2014.01.008openalex-snapshot
The two faces of IL-6 in the tumor microenvironment
inferredcites →https://doi.org/10.1016/j.tips.2007.02.002openalex-snapshot
Beneficial health effects of exercise – the role of IL-6 as a myokine
inferredcites →https://doi.org/10.1016/j.yexcr.2009.09.024openalex-snapshot
Oncostatin M (OSM) primes IL-13- and IL-4-induced eotaxin responses in fibroblasts: Regulation of the type-II IL-4 receptor chains IL-4Rα and IL-13Rα1
inferredcites →https://doi.org/10.1016/s0006-291x(02)00230-9openalex-snapshot
Intracerebroventricular interleukin-6 treatment decreases body fat in rats
inferredcites →https://doi.org/10.1016/s0306-4522(02)00447-5openalex-snapshot
Induction of uncoupling protein 1 by central interleukin-6 gene delivery is dependent on sympathetic innervation of brown adipose tissue and underlies one mechanism of body weight reduction in rats
inferredcites →https://doi.org/10.1016/s1074-7613(01)00151-0openalex-snapshot
IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation
inferredcites →https://doi.org/10.1016/s1074-7613(04)00107-4openalex-snapshot
Alternative Macrophage Activation Is Essential for Survival during Schistosomiasis and Downmodulates T Helper 1 Responses and Immunopathology
inferredcites →https://doi.org/10.1016/s1096-6374(03)00051-0openalex-snapshot
On the site and mechanism of action of the anti-obesity effects of interleukin-6
inferredcites →https://doi.org/10.1038/324073a0openalex-snapshot
Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin
inferredcites →https://doi.org/10.1038/43206openalex-snapshot
A family of cytokine-inducible inhibitors of signalling
inferredcites →https://doi.org/10.1038/75068openalex-snapshot
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo
inferredcites →https://doi.org/10.1038/nature05894openalex-snapshot
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
inferredcites →https://doi.org/10.1038/nature07475openalex-snapshot
Frequent in-frame somatic deletions activate gp130 in inflammatory hepatocellular tumours
inferredcites →https://doi.org/10.1038/nature10653openalex-snapshot
Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis
inferredcites →https://doi.org/10.1038/ncomms4460openalex-snapshot
Ammonia as a case study for the spontaneous ionization of a simple hydrogen-bonded compound
inferredcites →https://doi.org/10.1038/ncomms6798openalex-snapshot
STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13
inferredcites →https://doi.org/10.1038/ni.2865openalex-snapshot
Signaling by IL-6 promotes alternative activation of macrophages to limit endotoxemia and obesity-associated resistance to insulin
inferredcites →https://doi.org/10.1038/nm.2513openalex-snapshot
Interleukin-6 enhances insulin secretion by increasing glucagon-like peptide-1 secretion from L cells and alpha cells
inferredcites →https://doi.org/10.1038/nm.3549openalex-snapshot
Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis
inferredcites →https://doi.org/10.1038/nm0102-75openalex-snapshot
Interleukin-6-deficient mice develop mature-onset obesity
inferredcites →https://doi.org/10.1038/nm1166openalex-snapshot
Local and systemic insulin resistance resulting from hepatic activation of IKK-β and NF-κB
inferredcites →https://doi.org/10.1038/nm1185openalex-snapshot
IKK-β links inflammation to obesity-induced insulin resistance
inferredcites →https://doi.org/10.1038/nm980openalex-snapshot
Role of STAT-3 in regulation of hepatic gluconeogenic genes and carbohydrate metabolism in vivo
inferredcites →https://doi.org/10.1038/nrc1408openalex-snapshot
Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms
inferredcites →https://doi.org/10.1038/nri2921openalex-snapshot
Adipokines in inflammation and metabolic disease
inferredcites →https://doi.org/10.1038/nri2925openalex-snapshot
Type 2 diabetes as an inflammatory disease
inferredcites →https://doi.org/10.1038/nri3073openalex-snapshot
Protective and pathogenic functions of macrophage subsets
inferredcites →https://doi.org/10.1056/nejmcibr1409796openalex-snapshot
The Target of Metformin in Type 2 Diabetes
inferredcites →https://doi.org/10.1073/pnas.0707849104openalex-snapshot
Hepatic NF-κB essential modulator deficiency prevents obesity-induced insulin resistance but synergizes with high-fat feeding in tumorigenesis
inferredcites →https://doi.org/10.1073/pnas.0801059105openalex-snapshot
Interleukin-6 regulates pancreatic α-cell mass expansion
inferredcites →https://doi.org/10.1073/pnas.1106750109openalex-snapshot
The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines
inferredcites →https://doi.org/10.1073/pnas.1312525110openalex-snapshot
Acute inflammation primes myeloid effector cells for anti-inflammatory STAT6 signaling
inferredcites →https://doi.org/10.1073/pnas.1415191111openalex-snapshot
Individual differences in the peripheral immune system promote resilience versus susceptibility to social stress
inferredcites →https://doi.org/10.1073/pnas.83.23.8957openalex-snapshot
Anti-beta-interferon antibodies inhibit the increased expression of HLA-B7 mRNA in tumor necrosis factor-treated human fibroblasts: structural studies of the beta 2 interferon involved.
inferredcites →https://doi.org/10.1073/pnas.84.20.7251openalex-snapshot
Interferon beta 2/B-cell stimulatory factor type 2 shares identity with monocyte-derived hepatocyte-stimulating factor and regulates the major acute phase protein response in liver cells.
inferredcites →https://doi.org/10.1073/pnas.95.6.3251openalex-snapshot
Sympathetic neurons can produce and respond to interleukin 6
inferredcites →https://doi.org/10.1074/jbc.271.10.5487openalex-snapshot
A Di-leucine Motif and an Upstream Serine in the Interleukin-6 (IL-6) Signal Transducer gp130 Mediate Ligand-induced Endocytosis and Down-regulation of the IL-6 Receptor
inferredcites →https://doi.org/10.1074/jbc.271.16.9503openalex-snapshot
STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6
inferredcites →https://doi.org/10.1074/jbc.274.12.7793openalex-snapshot
The STAT3-independent Signaling Pathway by Glycoprotein 130 in Hepatic Cells
inferredcites →https://doi.org/10.1074/jbc.m113.461905openalex-snapshot
Lack of Oncostatin M Receptor β Leads to Adipose Tissue Inflammation and Insulin Resistance by Switching Macrophage Phenotype
inferredcites →https://doi.org/10.1074/jbc.m113.542399openalex-snapshot
Deficiency of Oncostatin M Receptor β (OSMRβ) Exacerbates High-fat Diet-induced Obesity and Related Metabolic Disorders in Mice
inferredcites →https://doi.org/10.1074/jbc.m210584200openalex-snapshot
Cellular Cholesterol Depletion Triggers Shedding of the Human Interleukin-6 Receptor by ADAM10 and ADAM17 (TACE)
inferredcites →https://doi.org/10.1074/jbc.m413930200openalex-snapshot
Activation of Stat3 Sequence-specific DNA Binding and Transcription by p300/CREB-binding Protein-mediated Acetylation
inferredcites →https://doi.org/10.1084/jem.157.2.583openalex-snapshot
B cell growth factors and B cell differentiation factor from human T hybridomas. Two distinct kinds of B cell growth factor and their synergism in B cell proliferation.
inferredcites →https://doi.org/10.1089/jir.2005.25.241openalex-snapshot
Review: IL-6 Transsignaling: The In Vivo Consequences
inferredcites →https://doi.org/10.1093/oxfordjournals.jbchem.a123261openalex-snapshot
Purification and Characterization of Soluble Human IL-6 Receptor Expressed in CHO Cells
inferredcites →https://doi.org/10.1101/gad.197590.112openalex-snapshot
Context-specific roles for paracrine IL-6 in lymphomagenesis
inferredcites →https://doi.org/10.1101/gad.211649.112openalex-snapshot
Adaptive thermogenesis in adipocytes: Is beige the new brown?
inferredcites →https://doi.org/10.1111/j.1432-1033.1986.tb09931.xopenalex-snapshot
Structural analysis of the sequence coding for an inducible 26‐kDa protein in human fibroblasts
inferredcites →https://doi.org/10.1111/j.1469-7793.2000.00237.xopenalex-snapshot
Production of interleukin‐6 in contracting human skeletal muscles can account for the exercise‐induced increase in plasma interleukin‐6
inferredcites →https://doi.org/10.1126/science.1061620openalex-snapshot
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
inferredcites →https://doi.org/10.1126/science.1140485openalex-snapshot
Gender Disparity in Liver Cancer Due to Sex Differences in MyD88-Dependent IL-6 Production
inferredcites →https://doi.org/10.1126/science.1160794openalex-snapshot
A Stress Signaling Pathway in Adipose Tissue Regulates Hepatic Insulin Resistance
inferredcites →https://doi.org/10.1126/science.1201475openalex-snapshot
Eosinophils Sustain Adipose Alternatively Activated Macrophages Associated with Glucose Homeostasis
inferredcites →https://doi.org/10.1126/science.274.5291.1379openalex-snapshot
Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice
inferredcites →https://doi.org/10.1126/science.289.5487.2122openalex-snapshot
Role of Brain Insulin Receptor in Control of Body Weight and Reproduction
inferredcites →https://doi.org/10.1126/science.3136546openalex-snapshot
Cloning and Expression of the Human Interleukin-6 (BSF-2/IFNβ 2) Receptor
inferredcites →https://doi.org/10.1126/science.7678183openalex-snapshot
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
inferredcites →https://doi.org/10.1128/mcb.18.7.4109openalex-snapshot
Gab1 Acts as an Adapter Molecule Linking the Cytokine Receptor gp130 to ERK Mitogen-Activated Protein Kinase
inferredcites →https://doi.org/10.1152/ajpendo.00189.2003openalex-snapshot
Lipid and carbohydrate metabolism in mice with a targeted mutation in the IL-6 gene: absence of development of age-related obesity
inferredcites →https://doi.org/10.1152/ajpendo.90996.2008openalex-snapshot
NIH experiment in centralized mouse phenotyping: the Vanderbilt experience and recommendations for evaluating glucose homeostasis in the mouse
inferredcites →https://doi.org/10.1152/jappl.1988.65.1.106openalex-snapshot
Strenuous exercise causes systemic endotoxemia
inferredcites →https://doi.org/10.1152/jappl.1995.79.5.1497openalex-snapshot
Endurance run increases circulating IL-6 and IL-1ra but downregulates ex vivo TNF-alpha and IL-1 beta production
inferredcites →https://doi.org/10.1172/jci19451openalex-snapshot
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
inferredcites →https://doi.org/10.1172/jci20514openalex-snapshot
Obesity-induced inflammatory changes in adipose tissue
inferredcites →https://doi.org/10.1172/jci29881openalex-snapshot
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
inferredcites →https://doi.org/10.1172/jci31871openalex-snapshot
Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
inferredcites →https://doi.org/10.1172/jci32533openalex-snapshot
IL-6 triggers malignant features in mammospheres from human ductal breast carcinoma and normal mammary gland
inferredcites →https://doi.org/10.1172/jci62308openalex-snapshot
Brown adipose tissue regulates glucose homeostasis and insulin sensitivity
inferredcites →https://doi.org/10.1182/blood-2005-03-1159openalex-snapshot
Time-course analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS
inferredcites →https://doi.org/10.1182/blood-2007-01-067918openalex-snapshot
Apoptosis is a natural stimulus of IL6R shedding and contributes to the proinflammatory trans-signaling function of neutrophils
inferredcites →https://doi.org/10.1182/blood-2007-02-072587openalex-snapshot
Tumor-associated leukemia inhibitory factor and IL-6 skew monocyte differentiation into tumor-associated macrophage-like cells
inferredcites →https://doi.org/10.1182/blood-2009-10-249540openalex-snapshot
Toll-like receptor–induced changes in glycolytic metabolism regulate dendritic cell activation
inferredcites →https://doi.org/10.1182/blood-2011-09-381483openalex-snapshot
Genome-wide analysis of STAT3 binding in vivo predicts effectors of the anti-inflammatory response in macrophages
inferredcites →https://doi.org/10.1182/blood.v74.1.1.bloodjournal7411openalex-snapshot
The biology of interleukin-6
inferredcites →https://doi.org/10.1182/blood.v82.4.1120.1120openalex-snapshot
Soluble forms of the interleukin-6 signal-transducing receptor component gp130 in human serum possessing a potential to inhibit signals through membrane-anchored gp130
inferredcites →https://doi.org/10.1210/en.2004-1468openalex-snapshot
Interleukin-6 Depletion Selectively Improves Hepatic Insulin Action in Obesity
inferredcites →https://doi.org/10.1210/jc.85.9.3338openalex-snapshot
Elevated Levels of Interleukin 6 Are Reduced in Serum and Subcutaneous Adipose Tissue of Obese Women after Weight Loss
inferredcites →https://doi.org/10.1210/jc.87.5.2084openalex-snapshot
Adipose Tissue IL-6 Content Correlates with Resistance to Insulin Activation of Glucose Uptake both in Vivo and in Vitro
inferredcites →https://doi.org/10.1210/me.2008-0264openalex-snapshot
STAT3 Targets the Regulatory Regions of Gluconeogenic Genes in Vivo
inferredcites →https://doi.org/10.1371/journal.pcbi.1002577openalex-snapshot
Quantifying the Contribution of the Liver to Glucose Homeostasis: A Detailed Kinetic Model of Human Hepatic Glucose Metabolism
inferredcites →https://doi.org/10.2337/db05-1404openalex-snapshot
Interleukin-6 Increases Insulin-Stimulated Glucose Disposal in Humans and Glucose Uptake and Fatty Acid Oxidation In Vitro via AMP-Activated Protein Kinase
inferredcites →https://doi.org/10.2337/db08-0872openalex-snapshot
Phenotypic Switching of Adipose Tissue Macrophages With Obesity Is Generated by Spatiotemporal Differences in Macrophage Subtypes
inferredcites →https://doi.org/10.2337/db08-1293openalex-snapshot
Activation of AMP-Activated Protein Kinase by Interleukin-6 in Rat Skeletal Muscle
inferredcites →https://doi.org/10.2337/diabetes.53.4.1060openalex-snapshot
Differential Effects of Interleukin-6 and -10 on Skeletal Muscle and Liver Insulin Action In Vivo
inferredcites →https://doi.org/10.4049/jimmunol.165.9.5227openalex-snapshot
Inhibition of IL-6 and IL-10 Signaling and Stat Activation by Inflammatory and Stress Pathways
inferredcites →https://doi.org/10.4049/jimmunol.169.5.2253openalex-snapshot
Shaping Gene Expression in Activated and Resting Primary Macrophages by IL-10
inferredcites →https://doi.org/10.4049/jimmunol.171.6.3202openalex-snapshot
Soluble IL-6 Receptor Governs IL-6 Activity in Experimental Arthritis: Blockade of Arthritis Severity by Soluble Glycoprotein 130
inferredcites →https://doi.org/10.4049/jimmunol.178.5.2813openalex-snapshot
Regulation of Suppressor of Cytokine Signaling 3 (SOCS3) mRNA Stability by TNF-α Involves Activation of the MKK6/p38MAPK/MK2 Cascade
inferredcites →https://doi.org/10.4161/jkst.23878openalex-snapshot
Mechanisms of chronic JAK-STAT3-SOCS3 signaling in obesity
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4679402openalex-extracted
Styryl Carbamates Backbones for the Discovery of TME-Disruptors Agents
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Nutritional Management of Oncologic Diseases
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Cowpea Mosaic Virus Promotes Anti‐Tumor Activity and Immune Memory in a Mouse Ovarian Tumor Model
inferred← citeshttps://doi.org/10.1002/advs.76416openalex-snapshot
Psychological Stress Associated Bile Acid Reprogramming Promotes Hepatocellular Carcinoma Progression
inferred← citeshttps://doi.org/10.1002/cam4.3106openalex-snapshot
Characterization of the immune profile of oral tongue squamous cell carcinomas with advancing disease
inferred← citeshttps://doi.org/10.1002/cbf.3701openalex-snapshot
Genetic deletion of IL‐6 increases CK‐MB, a classic cardiac damage marker, and decreases UPRmt genes after exhaustive exercise
inferred← citeshttps://doi.org/10.1002/elan.201600248openalex-snapshot
Development of Electrochemical Immunosensors towards Point‐of‐care Cancer Diagnostics: Clinically Relevant Studies
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Host Genetic Impact on Infectious Diseases among Different Ethnic Groups
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Neuromedin U alters bioenergetics and expands the cancer stem cell phenotype in HER2‐positive breast cancer
inferred← citeshttps://doi.org/10.1002/jcp.29781openalex-snapshot
RETRACTED: Coinhibition of S1PR1 and GP130 by siRNA‐loaded alginate‐conjugated trimethyl chitosan nanoparticles robustly blocks development of cancer cells
inferred← citeshttps://doi.org/10.1002/jcsm.13109openalex-snapshot
Interleukin‐6 initiates muscle‐ and adipose tissue wasting in a novel C57BL/6 model of cancer‐associated cachexia
inferred← citeshttps://doi.org/10.1002/jlb.3ma0120-578ropenalex-snapshot
Anti-inflammatory and metabolic reprogramming effects of MENK produce antitumor response in CT26 tumor-bearing mice
inferred← citeshttps://doi.org/10.1002/jso.25085openalex-snapshot
The association between preoperative serum interleukin‐6 levels and postoperative prognosis in patients with T2 gallbladder cancer
inferred← citeshttps://doi.org/10.1002/ptr.7345openalex-snapshot
Brazilian green propolis: A novel tool to improve the cytotoxic and immunomodulatory action of docetaxel on MCF ‐7 breast cancer cells and on women monocyte
inferred← citeshttps://doi.org/10.1007/978-3-031-09518-4_6openalex-snapshot
The Role of Interleukin-6/GP130 Cytokines in Cancer Cachexia
inferred← citeshttps://doi.org/10.1007/978-3-031-88361-3_22openalex-snapshot
Skeletal Muscle as Endocrine Organ
inferred← citeshttps://doi.org/10.1007/978-3-319-66475-0_2openalex-snapshot
Immune Surveillance in Health and Diseases of Aging: Definitions of Acute and Chronic Inflammation [Yin and Yang]
inferred← citeshttps://doi.org/10.1007/978-981-95-5651-9_4openalex-snapshot
Diabetes in Cancer Survivors
inferred← citeshttps://doi.org/10.1007/s00125-019-05045-yopenalex-snapshot
GLP-1 secretion is regulated by IL-6 signalling: a randomised, placebo-controlled study
inferred← citeshttps://doi.org/10.1007/s00395-021-00863-xopenalex-snapshot
Cytokines as therapeutic targets for cardio- and cerebrovascular diseases
inferred← citeshttps://doi.org/10.1007/s00424-017-1955-5openalex-snapshot
Macrophage function in obesity-induced inflammation and insulin resistance
inferred← citeshttps://doi.org/10.1007/s00436-023-08033-9openalex-snapshot
Ileal inflammation is reduced due to treatment with a metalloprotease from BmooMP-α-I snake venom in an experimental model of Toxoplasma gondii infection
inferred← citeshttps://doi.org/10.1007/s00438-022-01923-0openalex-snapshot
Development of a genetic risk score for obesity predisposition evaluation
inferred← citeshttps://doi.org/10.1007/s00705-025-06369-4openalex-snapshot
The mechanism of action of micafungin against pteropine orthoreovirus infection in the human A549 cell line
inferred← citeshttps://doi.org/10.1007/s10495-022-01763-8openalex-snapshot
DNA damage induces STING mediated IL-6-STAT3 survival pathway in triple-negative breast cancer cells and decreased survival of breast cancer patients
inferred← citeshttps://doi.org/10.1007/s10557-020-07106-6openalex-snapshot
Inflammation in Coronary Atherosclerosis and Its Therapeutic Implications.
inferred← citeshttps://doi.org/10.1007/s11332-023-01102-7openalex-snapshot
Muscle-to-organ cross-talk mediated by interleukin 6 during exercise: a review
inferred← citeshttps://doi.org/10.1007/s11926-019-0831-zopenalex-snapshot
Macrophages in Systemic Sclerosis: Novel Insights and Therapeutic Implications
inferred← citeshttps://doi.org/10.1007/s12026-017-8893-3openalex-snapshot
The improvement of M1 polarization in macrophages by glycopeptide derived from Ganoderma lucidum
inferred← citeshttps://doi.org/10.1007/s12079-021-00648-wopenalex-snapshot
Targeting of the tumor immune microenvironment by metformin
inferred← citeshttps://doi.org/10.1007/s12094-022-02833-8openalex-snapshot
The road-map for establishment of a prognostic molecular marker panel in glioma using liquid biopsy: current status and future directions
inferred← citeshttps://doi.org/10.1007/s12282-019-00966-3openalex-snapshot
PIM1 is responsible for IL-6-induced breast cancer cell EMT and stemness via c-myc activation
inferred← citeshttps://doi.org/10.1007/s12288-024-01947-zopenalex-snapshot
Assessment of TNF α and IL-6 Levels in Indian Patients of CML and their Correlation with Early Molecular Response: An Observational Study
inferred← citeshttps://doi.org/10.1007/s12640-024-00718-yopenalex-snapshot
Methylphenidate Exposing During Neurodevelopment Alters Amino Acid Profile, Astrocyte Marker and Glutamatergic Excitotoxicity in the Rat Striatum
inferred← citeshttps://doi.org/10.1007/s13193-021-01358-wopenalex-snapshot
Expression Levels of Il-6 and Il-18 in Acute Myeloid Leukemia and Its Relation with Response to Therapy and Acute GvHD After Bone Marrow Transplantation
inferred← citeshttps://doi.org/10.1007/s13277-016-5098-7openalex-snapshot
Role of interleukin-6 in cancer progression and therapeutic resistance
inferred← citeshttps://doi.org/10.1007/s13311-016-0461-3openalex-snapshot
Combined Metabolomics and Transcriptomics Approaches to Assess the IL-6 Blockade as a Therapeutic of ALS: Deleterious Alteration of Lipid Metabolism
inferred← citeshttps://doi.org/10.1007/s13402-022-00667-8openalex-snapshot
Roles for macrophage-polarizing interleukins in cancer immunity and immunotherapy
inferred← citeshttps://doi.org/10.1007/s42399-020-00473-zopenalex-snapshot
Interleukin-6 in Very Elderly Patients with Coronary Artery Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-814593-7.00013-xopenalex-snapshot
Muscle as an Endocrine Organ
inferred← citeshttps://doi.org/10.1016/b978-0-323-88426-6.00003-8openalex-snapshot
Cancer in diabetes: Who is who?
inferred← citeshttps://doi.org/10.1016/b978-0-443-13825-6.00346-0openalex-snapshot
The adipose tissue
inferred← citeshttps://doi.org/10.1016/b978-0-443-24080-5.00028-xopenalex-snapshot
Investigating fatigue in rats on high-fat regimen
inferred← citeshttps://doi.org/10.1016/bs.acc.2020.06.004openalex-snapshot
Cytokines and the immune response in obesity-related disorders
inferred← citeshttps://doi.org/10.1016/j.ajpath.2019.06.010openalex-snapshot
Blockade of Lymphangiogenesis Shapes Tumor-Promoting Adipose Tissue Inflammation
inferred← citeshttps://doi.org/10.1016/j.amjmed.2023.11.001openalex-snapshot
Effect of Periodontal Treatment on Reducing Chronic Inflammation in Systemically Healthy Patients With Periodontal Disease
inferred← citeshttps://doi.org/10.1016/j.amjms.2023.11.016openalex-snapshot
Construction of a hepatocellular carcinoma high-risk population rating scale and independent predictors' assessment
inferred← citeshttps://doi.org/10.1016/j.arr.2022.101697openalex-snapshot
The hormetic and hermetic role of IL-6
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2017.06.008openalex-snapshot
Proteolytic control of Interleukin-11 and Interleukin-6 biology
inferred← citeshttps://doi.org/10.1016/j.bbcan.2023.189023openalex-snapshot
Metabolic reprogramming in nasopharyngeal carcinoma: Mechanisms and therapeutic opportunities
inferred← citeshttps://doi.org/10.1016/j.bbi.2018.02.013openalex-snapshot
Rethinking IL-6 and CRP: Why they are more than inflammatory biomarkers, and why it matters
inferred← citeshttps://doi.org/10.1016/j.bbr.2021.113607openalex-snapshot
Neutralizing interleukin-6 in tumor-bearing mice does not abrogate behavioral fatigue induced by Lewis lung carcinoma
inferred← citeshttps://doi.org/10.1016/j.bbrc.2018.11.083openalex-snapshot
Interleukin-6 derived from cutaneous deficiency of stearoyl-CoA desaturase- 1 may mediate metabolic organ crosstalk among skin, adipose tissue and liver
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.11.032openalex-snapshot
HIF1α inhibits LPS-mediated induction of IL-6 synthesis via SOCS3-dependent CEBPβ suppression in human dental pulp cells
inferred← citeshttps://doi.org/10.1016/j.bioadv.2022.213128openalex-snapshot
Biomimetic surface topography as a potential modulator of macrophages inflammatory response to biomaterials
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2017.05.040openalex-snapshot
Augmented glioma-targeted theranostics using multifunctional polymer-coated carbon nanodots
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2021.120914openalex-snapshot
Cowpea mosaic virus stimulates antitumor immunity through recognition by multiple MYD88-dependent toll-like receptors
inferred← citeshttps://doi.org/10.1016/j.biopha.2017.05.055openalex-snapshot
Rheumatoid arthritis: Recent advances on its etiology, role of cytokines and pharmacotherapy
inferred← citeshttps://doi.org/10.1016/j.biopsycho.2023.108664openalex-snapshot
A perinatal coparenting intervention: Effects of a randomized trial on parent cardiometabolic risk and self-reported health
inferred← citeshttps://doi.org/10.1016/j.canlet.2017.07.014openalex-snapshot
Metabolic regulation of glioma stem-like cells in the tumor micro-environment
inferred← citeshttps://doi.org/10.1016/j.ccell.2020.06.007openalex-snapshot
IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
inferred← citeshttps://doi.org/10.1016/j.ccm.2019.05.001openalex-snapshot
Pulmonary Manifestations of Systemic Sclerosis and Mixed Connective Tissue Disease
inferred← citeshttps://doi.org/10.1016/j.cej.2025.170017openalex-snapshot
Development of a high-sensitivity interleukin-6 biosensor by combining nanobody engineering and solution-immersed silicon ellipsometry
inferred← citeshttps://doi.org/10.1016/j.cell.2016.04.039openalex-snapshot
Lung Adenocarcinoma Distally Rewires Hepatic Circadian Homeostasis
inferred← citeshttps://doi.org/10.1016/j.cell.2023.05.002openalex-snapshot
Distinct longevity mechanisms across and within species and their association with aging
inferred← citeshttps://doi.org/10.1016/j.cellsig.2021.109931openalex-snapshot
Down-regulation of GP130 signaling sensitizes bladder cancer to cisplatin by impairing Ku70 DNA repair signaling and promoting apoptosis
inferred← citeshttps://doi.org/10.1016/j.cellsig.2022.110371openalex-snapshot
WNK1 kinase signaling in metastasis and angiogenesis
inferred← citeshttps://doi.org/10.1016/j.celrep.2017.03.043openalex-snapshot
IL-6 Improves Energy and Glucose Homeostasis in Obesity via Enhanced Central IL-6 trans-Signaling
inferred← citeshttps://doi.org/10.1016/j.clcc.2025.12.001openalex-snapshot
Effects of Cancer Treatment on Inflammation in Colorectal Cancer Patients: A Longitudinal Study
inferred← citeshttps://doi.org/10.1016/j.clim.2017.08.012openalex-snapshot
Ficolin-2 triggers antitumor effect by activating macrophages and CD8+ T cells
inferred← citeshttps://doi.org/10.1016/j.cllc.2018.03.016openalex-snapshot
A Placebo-Controlled Phase II Study of Ruxolitinib in Combination With Pemetrexed and Cisplatin for First-Line Treatment of Patients With Advanced Nonsquamous Non–Small-Cell Lung Cancer and Systemic Inflammation
inferred← citeshttps://doi.org/10.1016/j.cmet.2016.01.011openalex-snapshot
Voluntary Running Suppresses Tumor Growth through Epinephrine- and IL-6-Dependent NK Cell Mobilization and Redistribution
inferred← citeshttps://doi.org/10.1016/j.cmet.2017.05.018openalex-snapshot
IL-6/Stat3-Dependent Induction of a Distinct, Obesity-Associated NK Cell Subpopulation Deteriorates Energy and Glucose Homeostasis
inferred← citeshttps://doi.org/10.1016/j.coi.2015.02.008openalex-snapshot
The IL-6/gp130/STAT3 signaling axis: recent advances towards specific inhibition
inferred← citeshttps://doi.org/10.1016/j.critrevonc.2024.104352openalex-snapshot
C-reactive protein (CRP) as a prognostic biomarker in patients with urothelial carcinoma: A systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.crmeth.2023.100502openalex-snapshot
Single-cell deep phenotyping of cytokine release unmasks stimulation-specific biological signatures and distinct secretion dynamics
inferred← citeshttps://doi.org/10.1016/j.cyto.2015.04.018openalex-snapshot
Muscular interleukin-6 differentially regulates skeletal muscle adaptation to high-fat diet in a sex-dependent manner
inferred← citeshttps://doi.org/10.1016/j.cyto.2019.02.001openalex-snapshot
The role of cytokines in the regulation of NK cells in the tumor environment
inferred← citeshttps://doi.org/10.1016/j.cyto.2020.155228openalex-snapshot
A combinational approach to restore cytokine balance and to inhibit virus growth may promote patient recovery in severe COVID-19 cases
inferred← citeshttps://doi.org/10.1016/j.cyto.2021.155684openalex-snapshot
Unravelling the broader complexity of IL-6 involvement in health and disease
inferred← citeshttps://doi.org/10.1016/j.cyto.2022.155889openalex-snapshot
Evaluation of the relationship between IL-6 gene single nucleotide polymorphisms and the severity of COVID-19 in an Iranian population
inferred← citeshttps://doi.org/10.1016/j.cyto.2024.156852openalex-snapshot
Exploring the mechanism and crosstalk between IL-6 and IL- 1β on M2 macrophages under metabolic stress conditions
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2015.07.009openalex-snapshot
Cardiotrophin-1: A multifaceted cytokine
inferred← citeshttps://doi.org/10.1016/j.cytogfr.2025.01.001openalex-snapshot
Interleukin-6 (IL-6)-associated tumor microenvironment remodelling and cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.dmpk.2025.101510openalex-snapshot
Current status of prediction of IL-6 mediated cytochrome P450 activity modulation using in vitro data and PBPK modeling
inferred← citeshttps://doi.org/10.1016/j.ebiom.2019.102612openalex-snapshot
Contribution of synergism between PHF8 and HER2 signalling to breast cancer development and drug resistance
inferred← citeshttps://doi.org/10.1016/j.ejps.2023.106380openalex-snapshot
The convergence of pharmacometrics and quantitative systems pharmacology in pharmaceutical research and development
inferred← citeshttps://doi.org/10.1016/j.exger.2021.111377openalex-snapshot
Is early life adversity a trigger towards inflammageing?
inferred← citeshttps://doi.org/10.1016/j.fbio.2022.101998openalex-snapshot
Utilizing lemon peel extract and its nano-emulsion to control aflatoxin toxicity in rats
inferred← citeshttps://doi.org/10.1016/j.hsr.2023.100098openalex-snapshot
Pathogenesis of obesity-associated cardiovascular diseases: Key role of biomolecules
inferred← citeshttps://doi.org/10.1016/j.intimp.2022.109130openalex-snapshot
Interleukin-6 cytokine: An overview of the immune regulation, immune dysregulation, and therapeutic approach
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111766openalex-snapshot
Calcitonin gene-related peptide-modulated macrophage phenotypic alteration regulates angiogenesis in early bone healing
inferred← citeshttps://doi.org/10.1016/j.intimp.2024.111906openalex-snapshot
Interleukin-6 promotes visceral adipose tissue accumulation during aging via inhibiting fat lipolysis
inferred← citeshttps://doi.org/10.1016/j.isci.2021.103325openalex-snapshot
Maturation trajectories and transcriptional landscape of plasmablasts and autoreactive B cells in COVID-19
inferred← citeshttps://doi.org/10.1016/j.jchromb.2026.125002openalex-snapshot
Characterization and development of an interleukin-6 reference material by SI-traceable isotope-dilution mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.jconrel.2020.01.044openalex-snapshot
Doxorubicin-polyglycerol-nanodiamond conjugates disrupt STAT3/IL-6-mediated reciprocal activation loop between glioblastoma cells and astrocytes
inferred← citeshttps://doi.org/10.1016/j.jep.2023.116679openalex-snapshot
System pharmacology analysis to decipher the effect and mechanism of active ingredients combination from Duhuo Jisheng decoction on osteoarthritis in rats
inferred← citeshttps://doi.org/10.1016/j.jff.2023.105879openalex-snapshot
Integrating network analysis and experimental validation to reveal the mechanism of pinocembrin in alleviating high glucose and free fatty acid-induced lipid accumulation in HepG2 cells
inferred← citeshttps://doi.org/10.1016/j.lfs.2018.11.060openalex-snapshot
A new chemotherapeutic approach using doxorubicin simultaneously with geopropolis favoring monocyte functions
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.118097openalex-snapshot
The bio-mission of interleukin-6 in the pathogenesis of COVID-19: A brief look at potential therapeutic tactics
inferred← citeshttps://doi.org/10.1016/j.mgene.2021.100972openalex-snapshot
The link between IL-6 rs2069840 SNP and cancer risk: Evidence from a systematic review and meta-analysis
inferred← citeshttps://doi.org/10.1016/j.molmet.2018.08.010openalex-snapshot
Hepatic leptin receptor expression can partially compensate for IL-6Rα deficiency in DEN-induced hepatocellular carcinoma
inferred← citeshttps://doi.org/10.1016/j.molmet.2019.05.001openalex-snapshot
What role do fat cells play in pancreatic tissue?
inferred← citeshttps://doi.org/10.1016/j.molmet.2020.101029openalex-snapshot
Lack of Gαi2 proteins in adipocytes attenuates diet-induced obesity
inferred← citeshttps://doi.org/10.1016/j.molmet.2025.102171openalex-snapshot
IL-6 decodes sex and diet-dependent circadian and metabolic rhythms
inferred← citeshttps://doi.org/10.1016/j.molonc.2015.08.001openalex-snapshot
Fibroblast activation protein‐α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations
inferred← citeshttps://doi.org/10.1016/j.nano.2021.102371openalex-snapshot
The prospects of nanotherapeutic approaches for targeting tumor-associated macrophages in oral cancer
inferred← citeshttps://doi.org/10.1016/j.neo.2022.100788openalex-snapshot
Myeloid-derived suppressor cells promote tumor growth and sorafenib resistance by inducing FGF1 upregulation and fibrosis
inferred← citeshttps://doi.org/10.1016/j.omtn.2017.06.009openalex-snapshot
Regulatory Role of the MicroRNA-29b-IL-6 Signaling in the Formation of Vascular Mimicry
inferred← citeshttps://doi.org/10.1016/j.phymed.2024.155451openalex-snapshot
A comprehensive review of phytochemicals targeting macrophages for the regulation of colorectal cancer progression
inferred← citeshttps://doi.org/10.1016/j.rec.2019.03.006openalex-snapshot
Potential Therapeutic Value of Interleukin 1b-targeted Strategies in Atherosclerotic Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/j.recesp.2019.02.021openalex-snapshot
Valor terapéutico potencial de las estrategias dirigidas contra la interleucina 1β en la enfermedad cardiovascular ateroesclerótica
inferred← citeshttps://doi.org/10.1016/j.rechem.2024.101372openalex-snapshot
Styryl carbamate backbones for the discovery of TME-disrupting agents
inferred← citeshttps://doi.org/10.1016/j.resinv.2024.11.015openalex-snapshot
Molecular mechanisms and clinical impact of biologic therapies in severe asthma
inferred← citeshttps://doi.org/10.1016/j.semcancer.2018.08.001openalex-snapshot
NK cells shape pancreatic and oral tumor microenvironments; role in inhibition of tumor growth and metastasis
inferred← citeshttps://doi.org/10.1016/j.semcancer.2025.03.007openalex-snapshot
Vitamin D: What role in obesity-related cancer?
inferred← citeshttps://doi.org/10.1016/j.sjbs.2020.10.065openalex-snapshot
Exercise-induced downregulation of serum interleukin-6 and tumor necrosis factor-alpha in Egyptian handball players
inferred← citeshttps://doi.org/10.1016/j.soi.2024.100045openalex-snapshot
Intra-pleural and intra-peritoneal tocilizumab therapy for managing malignant pleural effusions and ascites: The Regional Immuno-Oncology Trial (RIOT)−2 study protocol
inferred← citeshttps://doi.org/10.1016/j.survophthal.2017.05.003openalex-snapshot
Systemic and ocular fluid compounds as potential biomarkers in age-related macular degeneration
inferred← citeshttps://doi.org/10.1016/j.vaccine.2023.05.073openalex-snapshot
Evaluation of protection and immunity induced by infectious bronchitis vaccines administered by oculonasal, spray or gel routes in commercial broiler chicks
inferred← citeshttps://doi.org/10.1016/j.vetimm.2018.11.005openalex-snapshot
Piglet weight gain during the first two weeks of lactation influences the immune system development
inferred← citeshttps://doi.org/10.1016/j.xcrm.2022.100813openalex-snapshot
Anti-diabetic effects of GLP1 analogs are mediated by thermogenic interleukin-6 signaling in adipocytes
inferred← citeshttps://doi.org/10.1016/j.yexcr.2019.02.015openalex-snapshot
Interleukin-6 released from differentiating human beige adipocytes improves browning
inferred← citeshttps://doi.org/10.1016/j.yexcr.2020.111877openalex-snapshot
Detection of intracellular biomarkers in viable cells using millisecond pulsed electric fields
inferred← citeshttps://doi.org/10.1016/j.yexcr.2022.113112openalex-snapshot
IL-6 promotes chemoresistance via upregulating CD36 mediated fatty acids uptake in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1016/s1155-1941(19)58130-6openalex-snapshot
10.1016/s1155-1941(19)58130-6
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.9b01567openalex-snapshot
Design, Synthesis, and Biological Evaluation of Amidobenzimidazole Derivatives as Stimulator of Interferon Genes (STING) Receptor Agonists
inferred← citeshttps://doi.org/10.1021/acs.jproteome.6b00892openalex-snapshot
IL-6 Linkage to Exercise-Induced Shifts in Lipid-Related Metabolites: A Metabolomics-Based Analysis
inferred← citeshttps://doi.org/10.1038/am.2017.225openalex-snapshot
Molybdenum disulfide/graphene oxide nanocomposites show favorable lung targeting and enhanced drug loading/tumor-killing efficacy with improved biocompatibility
inferred← citeshttps://doi.org/10.1038/leu.2016.34openalex-snapshot
TGF-α and IL-6 plasma levels selectively identify CML patients who fail to achieve an early molecular response or progress in the first year of therapy
inferred← citeshttps://doi.org/10.1038/ncomms14803openalex-snapshot
Temporal and tissue-specific requirements for T-lymphocyte IL-6 signalling in obesity-associated inflammation and insulin resistance
inferred← citeshttps://doi.org/10.1038/s41388-018-0160-0openalex-snapshot
TET2-dependent IL-6 induction mediated by the tumor microenvironment promotes tumor metastasis in osteosarcoma
inferred← citeshttps://doi.org/10.1038/s41416-018-0301-9openalex-snapshot
Low-dose anti-inflammatory combinatorial therapy reduced cancer stem cell formation in patient-derived preclinical models for tumour relapse prevention
inferred← citeshttps://doi.org/10.1038/s41420-023-01638-0openalex-snapshot
Tumor suppressor p53 mediates interleukin-6 expression to enable cancer cell evasion of genotoxic stress
inferred← citeshttps://doi.org/10.1038/s41420-025-02776-3openalex-snapshot
Therapeutic targeting of STING-IL6/STAT3 axis to inhibit osteoclastic niche formation and breast cancer bone metastasis
inferred← citeshttps://doi.org/10.1038/s41422-019-0192-1openalex-snapshot
Intragenic antagonistic roles of protein and circRNA in tumorigenesis
inferred← citeshttps://doi.org/10.1038/s41467-022-31655-zopenalex-snapshot
Maternal and perinatal obesity induce bronchial obstruction and pulmonary hypertension via IL-6-FoxO1-axis in later life
inferred← citeshttps://doi.org/10.1038/s41467-024-51827-3openalex-snapshot
A metabolic crosstalk between liposarcoma and muscle sustains tumor growth
inferred← citeshttps://doi.org/10.1038/s41467-024-54684-2openalex-snapshot
Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study
inferred← citeshttps://doi.org/10.1038/s41467-025-58706-5openalex-snapshot
FFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes
inferred← citeshttps://doi.org/10.1038/s41540-020-00145-7openalex-snapshot
Mitigating the risk of cytokine release syndrome in a Phase I trial of CD20/CD3 bispecific antibody mosunetuzumab in NHL: impact of translational system modeling
inferred← citeshttps://doi.org/10.1038/s41565-018-0085-3openalex-snapshot
Nanoparticle-induced neuronal toxicity across placental barriers is mediated by autophagy and dependent on astrocytes
inferred← citeshttps://doi.org/10.1038/s41574-019-0174-xopenalex-snapshot
Physical activity and muscle–brain crosstalk
inferred← citeshttps://doi.org/10.1038/s41574-025-01197-7openalex-snapshot
Sarcopenia and MASLD: novel insights and the future
inferred← citeshttps://doi.org/10.1038/s41590-024-01872-3openalex-snapshot
The balance of STING signaling orchestrates immunity in cancer
inferred← citeshttps://doi.org/10.1038/s41598-017-04100-1openalex-snapshot
Macrophage responses to lipopolysaccharide are modulated by a feedback loop involving prostaglandin E2, dual specificity phosphatase 1 and tristetraprolin
inferred← citeshttps://doi.org/10.1038/s41598-018-34238-5openalex-snapshot
Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism
inferred← citeshttps://doi.org/10.1038/s41598-021-90843-xopenalex-snapshot
Inflammation-related plasma protein levels and association with adiposity measurements in young adults
inferred← citeshttps://doi.org/10.1038/s41598-022-08850-5openalex-snapshot
Exercise suppresses tumor growth independent of high fat food intake and associated immune dysfunction
inferred← citeshttps://doi.org/10.1038/s42003-024-06453-6openalex-snapshot
Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia
inferred← citeshttps://doi.org/10.1038/s42255-024-01079-8openalex-snapshot
Obesity-induced inflammation: connecting the periphery to the brain
inferred← citeshttps://doi.org/10.1038/srep17977openalex-snapshot
Divergent responses to thermogenic stimuli in BAT and subcutaneous adipose tissue from interleukin 18 and interleukin 18 receptor 1-deficient mice
inferred← citeshttps://doi.org/10.1039/d0bm01219jopenalex-snapshot
The unique potency of Cowpea mosaic virus (CPMV) in situ cancer vaccine
inferred← citeshttps://doi.org/10.1039/d2fo02450kopenalex-snapshot
Onchidium struma polysaccharides exhibit hypoglycemic activity and modulate the gut microbiota in mice with type 2 diabetes mellitus
inferred← citeshttps://doi.org/10.1039/d3ob01838eopenalex-snapshot
Design, synthesis, and cell-based in vitro assay of deoxyinosine-mixed SATE-dCDN prodrugs that activate all common STING variants
inferred← citeshttps://doi.org/10.1042/bst20180136openalex-snapshot
The role of the interleukin (IL)-6/IL-6 receptor axis in cancer
inferred← citeshttps://doi.org/10.1055/s-0040-1705259openalex-snapshot
IL-6: Sinalização na Hipertrofia Muscular e efeitos Metabólicos Sistêmicos
inferred← citeshttps://doi.org/10.1063/5.0320056openalex-snapshot
A comparative study of cytokines, vit-D and renal function in diabetic nephropathy patients in Thi-Qar Province, Iraq
inferred← citeshttps://doi.org/10.1073/pnas.1811040116openalex-snapshot
Dual mechanisms of posttranscriptional regulation of Tet2 by Let-7 microRNA in macrophages
inferred← citeshttps://doi.org/10.1073/pnas.1906712116openalex-snapshot
Feedback regulation of Arid5a and Ppar-γ2 maintains adipose tissue homeostasis
inferred← citeshttps://doi.org/10.1073/pnas.1920004117openalex-snapshot
Regulation of adipose tissue inflammation by interleukin 6
inferred← citeshttps://doi.org/10.1080/01635581.2020.1764982openalex-snapshot
Interleukin-6 and the Gut Microbiota Influence Melanoma Progression in Obese Mice
inferred← citeshttps://doi.org/10.1080/07391102.2023.2250452openalex-snapshot
Therapeutic efficacy of α-lactalbumin coated oleic acid based liposomes against colorectal carcinoma in Caco-2 cells and DMH-treated albino rats
inferred← citeshttps://doi.org/10.1080/07391102.2024.2426077openalex-snapshot
Potential mechanism of Laportea bulbifera on treating inflammation and tumor via metabolomics, network pharmacology and molecular docking
inferred← citeshttps://doi.org/10.1080/08923973.2020.1742733openalex-snapshot
Mechanism of tumor cells escaping from immune surveillance of NK cells
inferred← citeshttps://doi.org/10.1080/10520295.2025.2548792openalex-snapshot
Microscopic and ultrastructural insights into the protective role of melatonin against tartrazine-induced hepatotoxicity
inferred← citeshttps://doi.org/10.1080/14789450.2020.1845654openalex-snapshot
Multiomic analysis of cytokines in immuno-oncology
inferred← citeshttps://doi.org/10.1080/15548627.2022.2155794openalex-snapshot
Autophagy inhibition signals through senescence to promote tumor suppression
inferred← citeshttps://doi.org/10.1080/19490976.2017.1405209openalex-snapshot
Modulation of the gut microbiota by metformin improves metabolic profiles in aged obese mice
inferred← citeshttps://doi.org/10.1080/21623945.2020.1760674openalex-snapshot
Role of TLR4 in the induction of inflammatory changes in adipocytes and macrophages
inferred← citeshttps://doi.org/10.1080/2162402x.2018.1494110openalex-snapshot
IL-6 augments IL-4-induced polarization of primary human macrophages through synergy of STAT3, STAT6 and BATF transcription factors
inferred← citeshttps://doi.org/10.1080/26895293.2020.1732483openalex-snapshot
The synergistic effect of fenretinide and metformin to achieve a decrease in insulin resistance and inflammatory mediators: an in vivo study
inferred← citeshttps://doi.org/10.1089/rej.2018.2089openalex-snapshot
STAT3/c-Myc Axis-Mediated Metabolism Alternations of Inflammation-Related Glycolysis Involve with Colorectal Carcinogenesis
inferred← citeshttps://doi.org/10.1089/ten.tea.2019.0190openalex-snapshot
Controlling the Phenotype of Macrophages Promotes Maturation of Tissue-Engineered Cartilage
inferred← citeshttps://doi.org/10.1093/bib/bbaa259openalex-snapshot
Computer-aided prediction and design of IL-6 inducing peptides: IL-6 plays a crucial role in COVID-19
inferred← citeshttps://doi.org/10.1093/carcin/bgab102openalex-snapshot
Tocilizumab suppresses the pro-carcinogenic effects of breast cancer-associated fibroblasts through inhibition of the STAT3/AUF1 pathway
inferred← citeshttps://doi.org/10.1093/hmg/ddab023openalex-snapshot
Genome-wide association study of circulating interleukin 6 levels identifies novel loci
inferred← citeshttps://doi.org/10.1093/jb/mvz091openalex-snapshot
Interleukin-6 confers radio-resistance by inducing Akt mediated glycolysis and reducing mitochondrial damage in cells
inferred← citeshttps://doi.org/10.1096/fj.201801563ropenalex-snapshot
Cardiotrophin‐1 is an anti‐inflammatory cytokine and promotes IL‐4–induced M2 macrophage polarization
inferred← citeshttps://doi.org/10.1097/j.pain.0000000000001139openalex-snapshot
Disease modifying actions of interleukin-6 blockade in a rat model of bone cancer pain
inferred← citeshttps://doi.org/10.1097/mco.0000000000000283openalex-snapshot
Skeletal muscle as a gene regulatory endocrine organ
inferred← citeshttps://doi.org/10.1097/md.0000000000044804openalex-snapshot
Pathogenic mechanisms and treatment advances in proliferative vitreoretinopathy: A review
inferred← citeshttps://doi.org/10.1097/shk.0000000000000849openalex-snapshot
An ALPHA7 Nicotinic Acetylcholine Receptor Agonist (GTS-21) Promotes C2C12 Myonuclear Accretion in Association with Release of Interleukin-6 (IL-6) and Improves Survival in Burned Mice
inferred← citeshttps://doi.org/10.1097/shk.0000000000002550openalex-snapshot
INCREASED CIRCULATORY KREBS CYCLE METABOLITES IN SEPSIS IS ASSOCIATED WITH INCREASED INTERLEUKIN-6 RELEASE AND WORSE SURVIVAL
inferred← citeshttps://doi.org/10.1097/tp.0000000000003494openalex-snapshot
Intestinal Dysbiosis Correlates With Sirolimus-induced Metabolic Disorders in Mice
inferred← citeshttps://doi.org/10.1097/xce.0000000000000298openalex-snapshot
Chronic GLP1 therapy reduces postprandial IL6 in obese humans with prediabetes
inferred← citeshttps://doi.org/10.1101/2020.03.19.998351openalex-snapshot
CDK8 fine-tunes IL-6 transcriptional activities by limiting STAT3 resident time at the gene loci
inferred← citeshttps://doi.org/10.1101/2021.01.29.428838openalex-snapshot
MMP12 Knockout Prevent Weight and Muscle Loss Induced by Cancer Cachexia
inferred← citeshttps://doi.org/10.1101/2021.09.14.460246openalex-snapshot
Prolific Induction of IL-6 in Human Cells by SARS-CoV-2-derived Peptide is Attenuated by Recombinant Human Anti-inflammatory Cytokines made in planta
inferred← citeshttps://doi.org/10.1101/2023.06.02.543362openalex-snapshot
A metabolic crosstalk between liposarcoma and muscle sustains tumor growth
inferred← citeshttps://doi.org/10.1101/2025.01.23.634615openalex-snapshot
The mechanism of Micafungin action to Pteropine orthoreovirus infection in human cell line
inferred← citeshttps://doi.org/10.1101/682476openalex-snapshot
Synergistic interplay between PHF8 and HER2 signaling contributes to breast cancer development and drug resistance
inferred← citeshttps://doi.org/10.1101/gad.278549.116openalex-snapshot
Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma
inferred← citeshttps://doi.org/10.11106/ijt.2020.13.1.1openalex-snapshot
The Significance of Transcriptomic Signatures in the Multifocal Papillary Thyroid Carcinoma: Two mRNA Expression Patterns with Distinctive Clinical Behavior from The Cancer Genome Atlas (TCGA) Database
inferred← citeshttps://doi.org/10.1111/aji.13304openalex-snapshot
COVID‐19 and Treg/Th17 imbalance: Potential relationship to pregnancy outcomes
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