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Synergistic interplay between PHF8 and HER2 signaling contributes to breast cancer development and drug resistance

https://doi.org/10.1101/682476
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inferredcites →https://doi.org/10.1002/j.1460-2075.1987.tb04797.xopenalex-snapshot
Overexpression of the EGF receptor‐related proto‐oncogene erbB‐2 in human mammary tumor cell lines by different molecular mechanisms.
inferredcites →https://doi.org/10.1002/jcb.22781openalex-snapshot
Targeting chromosomal instability and tumour heterogeneity in HER2‐positive breast cancer
inferredcites →https://doi.org/10.1007/978-1-4939-1804-1_24openalex-snapshot
Epigenetic Inhibitors
inferredcites →https://doi.org/10.1016/j.bbagrm.2017.07.005openalex-snapshot
Histone demethylase PHF8 regulates hypoxia signaling through HIF1α and H3K4me3
inferredcites →https://doi.org/10.1016/j.bbrc.2014.07.076openalex-snapshot
The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer
inferredcites →https://doi.org/10.1016/j.canlet.2008.10.013openalex-snapshot
Overexpression of ErbB2 induces invasion of MCF10A human breast epithelial cells via MMP-9
inferredcites →https://doi.org/10.1016/j.cell.2009.06.044openalex-snapshot
Phosphorylation of the Human MicroRNA-Generating Complex Mediates MAPK/Erk Signaling
inferredcites →https://doi.org/10.1016/j.cell.2011.08.017openalex-snapshot
BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc
inferredcites →https://doi.org/10.1016/j.cell.2011.09.057openalex-snapshot
Combinatorial Patterning of Chromatin Regulators Uncovered by Genome-wide Location Analysis in Human Cells
inferredcites →https://doi.org/10.1016/j.celrep.2013.09.009openalex-snapshot
Chromatin Modifications Sequentially Enhance ErbB2 Expression in ErbB2-Positive Breast Cancers
inferredcites →https://doi.org/10.1016/j.celrep.2015.03.037openalex-snapshot
Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains
inferredcites →https://doi.org/10.1016/j.ejmech.2017.07.075openalex-snapshot
Recent advances in HER2 positive breast cancer epigenetics: Susceptibility and therapeutic strategies
inferredcites →https://doi.org/10.1016/j.it.2014.12.008openalex-snapshot
Versatile functions for IL-6 in metabolism and cancer
inferredcites →https://doi.org/10.1016/j.molcel.2010.03.002openalex-snapshot
A Functional Link between the Histone Demethylase PHF8 and the Transcription Factor ZNF711 in X-Linked Mental Retardation
inferredcites →https://doi.org/10.1016/j.phrs.2013.11.002openalex-snapshot
The ErbB/HER family of protein-tyrosine kinases and cancer
inferredcites →https://doi.org/10.1016/j.smim.2014.01.008openalex-snapshot
The two faces of IL-6 in the tumor microenvironment
inferredcites →https://doi.org/10.1023/a:1009528918064openalex-snapshot
Myc and Mammary Cancer: Myc is a Downstream Effector of the ErbB2 Receptor Tyrosine Kinase
inferredcites →https://doi.org/10.1038/nature07483openalex-snapshot
Regulation of ERBB2 by oestrogen receptor–PAX2 determines response to tamoxifen
inferredcites →https://doi.org/10.1038/nature09261openalex-snapshot
Histone H4K20/H3K9 demethylase PHF8 regulates zebrafish brain and craniofacial development
inferredcites →https://doi.org/10.1038/nature09272openalex-snapshot
PHF8 mediates histone H4 lysine 20 demethylation events involved in cell cycle progression
inferredcites →https://doi.org/10.1038/nbt.3519openalex-snapshot
Near-optimal probabilistic RNA-seq quantification
inferredcites →https://doi.org/10.1038/ncomms7702openalex-snapshot
IL-6-mediated environmental conditioning of defective Th1 differentiation dampens antitumour immune responses in old age
inferredcites →https://doi.org/10.1038/ni.2224openalex-snapshot
Inflammasomes in carcinogenesis and anticancer immune responses
inferredcites →https://doi.org/10.1038/ni.3153openalex-snapshot
IL-6 as a keystone cytokine in health and disease
inferredcites →https://doi.org/10.1038/nmeth.4324openalex-snapshot
Differential analysis of RNA-seq incorporating quantification uncertainty
inferredcites →https://doi.org/10.1038/nrc2656openalex-snapshot
Novel anticancer targets: revisiting ERBB2 and discovering ERBB3
inferredcites →https://doi.org/10.1038/nrg3173openalex-snapshot
Histone methylation: a dynamic mark in health, disease and inheritance
inferredcites →https://doi.org/10.1038/nsmb.1778openalex-snapshot
PHF8 activates transcription of rRNA genes through H3K4me3 binding and H3K9me1/2 demethylation
inferredcites →https://doi.org/10.1038/onc.2011.512openalex-snapshot
Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion
inferredcites →https://doi.org/10.1038/onc.2011.547openalex-snapshot
Modeling invasive breast cancer: growth factors propel progression of HER2-positive premalignant lesions
inferredcites →https://doi.org/10.1038/onc.2012.400openalex-snapshot
Transcriptional regulation of the GPX1 gene by TFAP2C and aberrant CpG methylation in human breast cancer
inferredcites →https://doi.org/10.1038/onc.2013.368openalex-snapshot
c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer
inferredcites →https://doi.org/10.1038/onc.2015.489openalex-snapshot
HER2 induced EMT and tumorigenicity in breast epithelial progenitor cells is inhibited by coexpression of EGFR
inferredcites →https://doi.org/10.1038/onc.2017.382openalex-snapshot
A novel HER2 gene body enhancer contributes to HER2 expression
inferredcites →https://doi.org/10.1038/sj.onc.1203303openalex-snapshot
AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen
inferredcites →https://doi.org/10.1042/bj20021238openalex-snapshot
Identification of HTF (HER2 transcription factor) as an AP-2 (activator protein-2) transcription factor and contribution of the HTF binding site to ERBB2 gene overexpression
inferredcites →https://doi.org/10.1056/nejmc0801440openalex-snapshot
HER2Status and Benefit from Adjuvant Trastuzumab in Breast Cancer
inferredcites →https://doi.org/10.1073/pnas.0506580102openalex-snapshot
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
inferredcites →https://doi.org/10.1073/pnas.0808300106openalex-snapshot
Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation
inferredcites →https://doi.org/10.1089/jir.2014.0026openalex-snapshot
The Role of Cytokines in Breast Cancer Development and Progression
inferredcites →https://doi.org/10.1093/hmg/ddp480openalex-snapshot
PHF8, a gene associated with cleft lip/palate and mental retardation, encodes for an Nε-dimethyl lysine demethylase
inferredcites →https://doi.org/10.1093/nar/gkw1093openalex-snapshot
Histone demethylase PHF8 promotes epithelial to mesenchymal transition and breast tumorigenesis
inferredcites →https://doi.org/10.1093/nar/gkw1346openalex-snapshot
The histone demethylase PHF8 is a molecular safeguard of the IFNγ response
inferredcites →https://doi.org/10.1093/nar/gkx247openalex-snapshot
GEPIA: a web server for cancer and normal gene expression profiling and interactive analyses
inferredcites →https://doi.org/10.1093/nar/gky1131openalex-snapshot
STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets
inferredcites →https://doi.org/10.1097/mpa.0b013e31823cdd10openalex-snapshot
IL-6 Stimulates STAT3 and Pim-1 Kinase in Pancreatic Cancer Cell Lines
inferredcites →https://doi.org/10.1128/mcb.01520-09openalex-snapshot
PHF8 Targets Histone Methylation and RNA Polymerase II To Activate Transcription
inferredcites →https://doi.org/10.1155/2014/852748openalex-snapshot
Human Epidermal Growth Factor Receptor 2 (HER2) in Cancers: Overexpression and Therapeutic Implications
inferredcites →https://doi.org/10.1158/0008-5472.can-10-1529openalex-snapshot
HER-2 Signaling, Acquisition of Growth Factor Independence, and Regulation of Biological Networks Associated with Cell Transformation
inferredcites →https://doi.org/10.1158/0008-5472.can-17-2761openalex-snapshot
HER2 Overexpression Triggers an IL1α Proinflammatory Circuit to Drive Tumorigenesis and Promote Chemotherapy Resistance
inferredcites →https://doi.org/10.1158/1078-0432.ccr-12-1436openalex-snapshot
HER2-Associated Radioresistance of Breast Cancer Stem Cells Isolated from HER2-Negative Breast Cancer Cells
inferredcites →https://doi.org/10.1172/jci44952openalex-snapshot
IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells
inferredcites →https://doi.org/10.1172/jci85747openalex-snapshot
Stabilization of histone demethylase PHF8 by USP7 promotes breast carcinogenesis
inferredcites →https://doi.org/10.1186/1471-2407-9-279openalex-snapshot
Identification of target genes of transcription factor activator protein 2 gamma in breast cancer cells
inferredcites →https://doi.org/10.1186/1476-4598-5-24openalex-snapshot
Optimized high-throughput microRNA expression profiling provides novel biomarker assessment of clinical prostate and breast cancer biopsies.
inferredcites →https://doi.org/10.1186/1752-0509-3-1openalex-snapshot
Modeling ERBB receptor-regulated G1/S transition to find novel targets for de novo trastuzumab resistance
inferredcites →https://doi.org/10.1186/s12885-015-1869-6openalex-snapshot
A Her2-let-7-β2-AR circuit affects prognosis in patients with Her2-positive breast cancer
inferredcites →https://doi.org/10.1186/s13046-018-0890-4openalex-snapshot
PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma
inferredcites →https://doi.org/10.1186/s13046-018-0944-7openalex-snapshot
Correction to: PHF8 upregulation contributes to autophagic degradation of E-cadherin, epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma
inferredcites →https://doi.org/10.1309/8a2d-jft0-7ne6-ewheopenalex-snapshot
Detection and Quantitation of HER-2 Gene Amplification and Protein Expression in Breast Carcinoma
inferredcites →https://doi.org/10.1371/journal.pone.0077353openalex-snapshot
Oncogenic Features of PHF8 Histone Demethylase in Esophageal Squamous Cell Carcinoma
inferredcites →https://doi.org/10.1667/rr1472.1openalex-snapshot
NF-κB-MediatedHER2Overexpression inRadiation-Adaptive Resistance
inferredcites →https://doi.org/10.18632/oncotarget.12310openalex-snapshot
c-MYC drives histone demethylase PHF8 during neuroendocrine differentiation and in castration-resistant prostate cancer
inferredcites →https://doi.org/10.2174/1381612822666151124234417openalex-snapshot
Interleukin-6: A Critical Cytokine in Cancer Multidrug Resistance
inferredcites →https://doi.org/10.3322/caac.21551openalex-snapshot
Cancer statistics, 2019
inferredcites →https://doi.org/10.3390/cancers11010013openalex-snapshot
Interplay between Epigenetics, Expression of Estrogen Receptor- α, HER2/ERBB2 and Sensitivity of Triple Negative Breast Cancer Cells to Hormonal Therapy
inferredcites →https://doi.org/10.3892/ijo.2013.2195openalex-snapshot
STAT3 activation in HER2-overexpressing breast cancer promotes epithelial-mesenchymal transition and cancer stem cell traits
inferredcites →https://doi.org/10.3892/ijo.2017.4108openalex-snapshot
Cooperative oncogenic effect and cell signaling crosstalk of co-occurring HER2 and mutant PIK3CA in mammary epithelial cells
inferredcites →https://doi.org/10.3892/ijo_00000524openalex-snapshot
ErbB2-enhanced invasiveness of H-Ras MCF10A breast cells requires MMP-13 and uPA upregulation via p38 MAPK signaling
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