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Lipophilic extracts of Leucas zeylanica, a multi-purpose medicinal plant in the tropics, inhibit key enzymes involved in inflammation and gout
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/ptr.1603openalex-snapshot
Lipoxygenase inhibitors from natural plant sources. Part 1: Medicinal plants with inhibitory activity on arachidonate 5‐lipoxygenase and 5‐lipoxygenase[sol ]cyclooxygenase
inferredcites →https://doi.org/10.1016/b978-0-12-819218-4.00004-3openalex-snapshot
Multitarget approach for natural products in inflammation
inferredcites →https://doi.org/10.1016/j.bcp.2015.06.022openalex-snapshot
Perspective of microsomal prostaglandin E2 synthase-1 as drug target in inflammation-related disorders
inferredcites →https://doi.org/10.1016/j.biotechadv.2018.02.010openalex-snapshot
Natural products as inhibitors of prostaglandin E2 and pro-inflammatory 5-lipoxygenase-derived lipid mediator biosynthesis
inferredcites →https://doi.org/10.1016/j.drudis.2014.08.006openalex-snapshot
Multi-target approach for natural products in inflammation
inferredcites →https://doi.org/10.1016/j.ejphar.2007.04.059openalex-snapshot
Anti-inflammatory effects of compounds alpha-humulene and (−)-trans-caryophyllene isolated from the essential oil of Cordia verbenacea
inferredcites →https://doi.org/10.1016/j.sajb.2006.09.004openalex-snapshot
Antimycobacterial activity of some trees used in South African traditional medicine
inferredcites →https://doi.org/10.1016/j.tibs.2007.06.002openalex-snapshot
5-Lipoxygenase: regulation of expression and enzyme activity
inferredcites →https://doi.org/10.1016/s0022-2275(20)39128-8openalex-snapshot
Antioxidant and prooxidant activity of alpha-tocopherol in human plasma and low density lipoprotein.
inferredcites →https://doi.org/10.1021/acs.jmedchem.5b01750openalex-snapshot
Design and Development of Microsomal Prostaglandin E 2 Synthase-1 Inhibitors: Challenges and Future Directions
inferredcites →https://doi.org/10.1021/jm801085sopenalex-snapshot
Pirinixic Acid Derivatives as Novel Dual Inhibitors of Microsomal Prostaglandin E2Synthase-1 and 5-Lipoxygenase
inferredcites →https://doi.org/10.1038/1811199a0openalex-snapshot
Antioxidant Determinations by the Use of a Stable Free Radical
inferredcites →https://doi.org/10.1038/288183a0openalex-snapshot
Vitamin E modulates the lipoxygenation of arachidonic acid in leukocytes
inferredcites →https://doi.org/10.1055/s-2003-45141openalex-snapshot
Anti-Inflammatory Compounds of Plant Origin. Part I. Action on Arachidonic Acid Pathway, Nitric Oxide and Nuclear Factor κ B (NF-κB)
inferredcites →https://doi.org/10.1055/s-2007-990242openalex-snapshot
Inhibition of 5-Lipoxygenase Product Synthesis by Natural Compounds of Plant Origin
inferredcites →https://doi.org/10.1056/nejm199012203232505openalex-snapshot
The Effects of a 5-Lipoxygenase Inhibitor on Asthma Induced by Cold, Dry Air
inferredcites →https://doi.org/10.1073/pnas.0803601105openalex-snapshot
Beta-caryophyllene is a dietary cannabinoid
inferredcites →https://doi.org/10.1080/13543776.2017.1276568openalex-snapshot
Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents
inferredcites →https://doi.org/10.1080/13543776.2017.1344218openalex-snapshot
Microsomal prostaglandin E2 synthase-1 inhibitors: a patent review
inferredcites →https://doi.org/10.1080/21553769.2014.901926openalex-snapshot
Total phenolics, antioxidant and xanthine oxidase inhibitory activity of three colored onions (Allium cepaL.)
inferredcites →https://doi.org/10.1093/jac/48.suppl_1.5openalex-snapshot
Determination of minimum inhibitory concentrations
inferredcites →https://doi.org/10.1096/fj.02-0815fjeopenalex-snapshot
Phosphorylation‐ and stimulus‐dependent inhibition of cellular 5‐lipoxygenase activity by nonredox‐type inhibitors
inferredcites →https://doi.org/10.1146/annurev-med-011209-153129openalex-snapshot
Emotion Recollected in Tranquility: Lessons Learned from the COX-2 Saga
inferredcites →https://doi.org/10.1186/ar1908openalex-snapshot
The inflammatory process of gout and its treatment.
inferredcites →https://doi.org/10.1186/s12906-016-1455-8openalex-snapshot
Photoprotective potential in some medicinal plants used to treat skin diseases in Sri Lanka
inferredcites →https://doi.org/10.1517/13543771003602012openalex-snapshot
5-Lipoxygenase inhibitors: a review of recent developments and patents
inferredcites →https://doi.org/10.2174/092986709789578178openalex-snapshot
Inhibitors of the Microsomal Prostaglandin E2 Synthase-1 as Alternative to Non Steroidal Anti-Inflammatory Drugs (NSAIDs) – A Critical Review
inferredcites →https://doi.org/10.3329/icpj.v2i9.16076openalex-snapshot
Leucas zeylanica (L.) R. Br. protects ethanol and hydrogen peroxide-induced oxidative stress on hepatic tissue of rats
inferredcites →https://doi.org/10.5897/jpp.9000002openalex-snapshot
A review of plants of genus Leucas
inferredcites →https://doi.org/10.7439/ijpp.v2i5.617openalex-snapshot
In silico docking studies and in vitro xanthine oxidase inhibitory activity of commercially available terpenoids
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.2139/ssrn.4689659openalex-extracted
Anti-Inflammatory Diterpenoids from the Aerial Parts of Leucas Zeylanica
inferred← citeshttps://doi.org/10.1002/bmc.4726openalex-snapshot
Promotion of a quality standard for Porana sinensis Hemsl. based on the efficacy‐oriented Effect‐Constituent Index
inferred← citeshttps://doi.org/10.1002/ptr.8211openalex-snapshot
Herbal remedies in the management of hyperuricemia and gout: A review of in vitro, in vivo and clinical evidences
inferred← citeshttps://doi.org/10.1007/s10600-021-03560-2openalex-snapshot
Bioactive Chemical Constituents of Leucas zeylanica
inferred← citeshttps://doi.org/10.1007/s11655-022-3721-6openalex-snapshot
Effects of Total Saponins from Dioscorea Nipponica Makino on Monosodium Urate-Induced M1-Polarized Macrophages through Arachidonic Acid Signaling Pathway: An in vitro Study
inferred← citeshttps://doi.org/10.1007/s44372-025-00122-6openalex-snapshot
Evaluation of antioxidant, acetylcholinesterase, lipase, α-amylase, xanthine oxidase, and α-glucosidase enzyme inhibitory activities of Sri Lankan tea cultivars
inferred← citeshttps://doi.org/10.1016/b978-0-12-817903-1.00013-9openalex-snapshot
Bioactive natural products as potent inhibitors of xanthine oxidase
inferred← citeshttps://doi.org/10.1016/j.fitote.2024.105948openalex-snapshot
Four new diterpenoids from the aerial parts of Leucas zeylanica (L.) R. Br.
inferred← citeshttps://doi.org/10.1016/j.phrs.2021.105977openalex-snapshot
Microsomal prostaglandin E2 synthase-1 and its inhibitors: Molecular mechanisms and therapeutic significance
inferred← citeshttps://doi.org/10.1080/15287394.2021.2002744openalex-snapshot
Licania rigida leaf extract: Protective effect on oxidative stress, associated with cytotoxic, mutagenic and preclinical aspects
inferred← citeshttps://doi.org/10.11113/mjfas.v17n6.2306openalex-snapshot
Bioactivity Evaluation of Leucas zeylanica and its Phytochemicals
inferred← citeshttps://doi.org/10.11113/mjfas.v20n2.3464openalex-snapshot
Investigation on Optimized Flavonoid Extraction from Leucas zeylanica and Its Anthelmintic Activity
inferred← citeshttps://doi.org/10.1155/2019/2969364openalex-snapshot
Suppressive Effect of Huzhentongfeng on Experimental Gouty Arthritis: An In Vivo and In Vitro Study
inferred← citeshttps://doi.org/10.1155/2019/5985207openalex-snapshot
Development of Novel Topical Cosmeceutical Formulations from Nigella sativa L. with Antimicrobial Activity against Acne-Causing Microorganisms
inferred← citeshttps://doi.org/10.1155/2020/6950206openalex-snapshot
Chinese Medicine Huzhen Tongfeng Formula Effectively Attenuates Gouty Arthritis by Inhibiting Arachidonic Acid Metabolism and Inflammatory Mediators
inferred← citeshttps://doi.org/10.14233/ajchem.2023.26874openalex-snapshot
Bioactive Phytoconstituents of Leucas zeylanica and its Molecular Docking Study
inferred← citeshttps://doi.org/10.2174/0122103155341864250108062025openalex-snapshot
Potential Plant-based Remedies for Gouty Arthritis: A Comprehensive Review on Counterweighing the Inflammatory Pathways
inferred← citeshttps://doi.org/10.2174/1381612826666200728144605openalex-snapshot
Natural Products and Extracts as Xantine Oxidase Inhibitors - A Hope for Gout Disease?
inferred← citeshttps://doi.org/10.2174/1568026619666191029145209openalex-snapshot
A Paradigm Shift in the Development of Anti-Candida Drugs
inferred← citeshttps://doi.org/10.21931/rb/2020.05.04.18openalex-snapshot
Phytochemical screening and in vitro anti-inflammatory activity of ethanolic extract of Epidendrum coryophorum leaves.
inferred← citeshttps://doi.org/10.22159/ajpcr.2025v18i8.55364openalex-snapshot
EVALUATION OF HEPATOPROTECTIVE POTENTIAL OF APOCYNACEAE FAMILY PLANTS IN RAT MODELS OF ALCOHOL, PARACETAMOL, AND RANITIDINE-INDUCED HEPATOTOXICITY
inferred← citeshttps://doi.org/10.30574/gscbps.2021.16.1.0184openalex-snapshot
Leucas zeylanica is a Bangladeshi plant with significant medicinal prospect: A review
inferred← citeshttps://doi.org/10.33086/etm.v1i2.2072openalex-snapshot
Phytochemical and Toxicity Analysis of Leucas zeylanica crude extracts
inferred← citeshttps://doi.org/10.3389/fimmu.2025.1671548openalex-snapshot
Fatty acid metabolism in gouty arthritis: mechanisms to therapeutic targeting
inferred← citeshttps://doi.org/10.3389/fnut.2021.676346openalex-snapshot
Metabolites of Procyanidins From Litchi Chinensis Pericarp With Xanthine Oxidase Inhibitory Effect and Antioxidant Activity
inferred← citeshttps://doi.org/10.3389/fphar.2021.759157openalex-snapshot
Integrated Strategy From In Vitro, In Situ, In Vivo to In Silico for Predicting Active Constituents and Exploring Molecular Mechanisms of Tongfengding Capsule for Treating Gout by Inhibiting Inflammatory Responses
inferred← citeshttps://doi.org/10.3390/molecules25081894openalex-snapshot
The Anti-Inflammatory and Antimicrobial Potential of Selected Ethnomedicinal Plants from Sri Lanka
inferred← citeshttps://doi.org/10.3390/ph15040436openalex-snapshot
Plectranthus zeylanicus: A Rich Source of Secondary Metabolites with Antimicrobial, Disinfectant and Anti-Inflammatory Activities
inferred← citeshttps://doi.org/10.37966/ijkiu2023042041openalex-snapshot
Development of herbal skin care formulations from the hydro-alcoholic extract of Leucas zeylanica (L.) W.T.Aiton
inferred← citeshttps://doi.org/10.4038/jsc.v14i1.60openalex-snapshot
Development of novel topical cosmeceutical formulations with antimicrobial activity against acne-causing microorganisms from Coriandrum sativum L.
inferred← citeshttps://doi.org/10.48048/tis.2022.2583openalex-snapshot
Phytochemical and Xanthine Oxidase Inhibitory Activity in Nypa fruticans Wurmb. Fruit Extracts
inferred← citeshttps://doi.org/10.53023/p.rasayan-20211102openalex-snapshot
In vitro evaluation of UV-filtering and anti-tyrosinase potential in selected medicinal plants in Sri Lanka for the development of herbal cosmetics
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