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An Adversarial DNA N6-Methyladenine-Sensor Network Preserves Polycomb Silencing

https://doi.org/10.1016/j.molcel.2019.03.018

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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CG14906 (mettl4) mediates m6A methylation of U2 snRNA in Drosophila

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N6-methyladenine is incorporated into mammalian genome by DNA polymerase

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DNA N6-methyladenine methylase N6AMT1 controls neuropathic pain through epigenetically modifying Kcnj16 in dorsal horn neurons

inferred← citeshttps://doi.org/10.1101/2022.12.15.520167openalex-snapshot

Multi-omics on truncating ASXL1 mutations in Bohring Opitz syndrome identify dysregulation of canonical and non-canonical Wnt signaling

inferred← citeshttps://doi.org/10.1101/2023.01.16.524325openalex-snapshot

Sequencing of N 6 -methyl-deoxyadenosine at single-base resolution across the mammalian genome

inferred← citeshttps://doi.org/10.1101/2023.03.08.531649openalex-snapshot

The Loss of the E3 ubiquitin ligase TRIP12 inhibits Pancreatic Acinar Cell Plasticity and Tumor Cell Metastatic Capacity

inferred← citeshttps://doi.org/10.1101/2023.06.07.544091openalex-snapshot

Prokaryotic winged helix domains as dsDNA adenine methylation sensors

inferred← citeshttps://doi.org/10.1101/2023.09.13.556486openalex-snapshot

The intrinsically disordered region of the E3 ubiquitin ligase TRIP12 induces the formation of chromatin condensates and interferes with DNA damage response

inferred← citeshttps://doi.org/10.1101/2025.06.10.658764openalex-snapshot

A distinct class of eukaryotic demethylases safeguards the positional fidelity of N 6 -methyladenine (6mA)

inferred← citeshttps://doi.org/10.1111/imb.12865openalex-snapshot

Functional characterisation of Fe ( II ) and 2OG ‐dependent dioxygenase TcALKBH4 in the red flour beetle, Tribolium castaneum

inferred← citeshttps://doi.org/10.1111/nph.18117openalex-snapshot

MTA1‐mediated RNA m 6 A modification regulates autophagy and is required for infection of the rice blast fungus

inferred← citeshttps://doi.org/10.1126/science.abe9582openalex-snapshot

FTO mediates LINE1 m 6 A demethylation and chromatin regulation in mESCs and mouse development

inferred← citeshttps://doi.org/10.1128/msphere.01208-20openalex-snapshot

Case Study of the Response of N 6 -Methyladenine DNA Modification to Environmental Stressors in the Unicellular Eukaryote Tetrahymena thermophila

inferred← citeshttps://doi.org/10.1155/2020/1047896openalex-snapshot

Epigenetic Clock: DNA Methylation in Aging

inferred← citeshttps://doi.org/10.11569/wcjd.v28.i11.428openalex-snapshot

Molecular mechanism of methyltransferase-like protein family: Relationship with gastric cancer

inferred← citeshttps://doi.org/10.1158/0008-5472.c.6513891.v1openalex-snapshot

Data from Oncogenic and Tumor-Suppressive Functions of the RNA Demethylase FTO

inferred← citeshttps://doi.org/10.1158/0008-5472.can-21-3710openalex-snapshot

Oncogenic and Tumor-Suppressive Functions of the RNA Demethylase FTO

inferred← citeshttps://doi.org/10.1158/0008-5472.can-25-4336openalex-snapshot

MPND Loss Epigenetically Activates TGFβ/SMAD3 Signaling to Drive Tumor Progression and Metastasis in Non–Small Cell Lung Cancer

inferred← citeshttps://doi.org/10.1161/circulationaha.123.068358openalex-snapshot

Rectifying METTL4-Mediated N 6 -Methyladenine Excess in Mitochondrial DNA Alleviates Heart Failure

inferred← citeshttps://doi.org/10.1161/circulationaha.125.075258openalex-snapshot

Letter by Sun and Ren Regarding Article, “METTL4-Mediated Mitochondrial DNA N6-Methyldeoxyadenosine Promoting Macrophage Inflammation and Atherosclerosis”

inferred← citeshttps://doi.org/10.1161/hypertensionaha.124.24491openalex-snapshot

Targeting N 6 -Methyladenine of Tubular Mitochondrial DNA Against Hypertensive CKD

inferred← citeshttps://doi.org/10.1172/jci.insight.167744openalex-snapshot

Multiomics of Bohring-Opitz syndrome truncating ASXL1 mutations identify canonical and noncanonical Wnt signaling dysregulation

inferred← citeshttps://doi.org/10.1186/s12920-021-01066-yopenalex-snapshot

Exome sequencing identifies novel and known mutations in families with intellectual disability

inferred← citeshttps://doi.org/10.1186/s13059-022-02819-3openalex-snapshot

METTL4-mediated nuclear N6-deoxyadenosine methylation promotes metastasis through activating multiple metastasis-inducing targets

inferred← citeshttps://doi.org/10.1186/s13059-023-03042-4openalex-snapshot

A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.1242/dev.202795openalex-snapshot

HemK2 functions for sufficient protein synthesis and RNA stability through eRF1 methylation during Drosophila oogenesis

inferred← citeshttps://doi.org/10.1371/journal.pgen.1008252openalex-snapshot

The demethylase NMAD-1 regulates DNA replication and repair in the Caenorhabditis elegans germline

inferred← citeshttps://doi.org/10.1371/journal.ppat.1012553openalex-snapshot

The novel roles of RNA m6A modification in regulating the development, infection, and oxidative DNA damage repair of Phytophthora sojae

inferred← citeshttps://doi.org/10.15252/embj.2020105977openalex-snapshot

m6A RNA methylation: from mechanisms to therapeutic potential

inferred← citeshttps://doi.org/10.20892/j.issn.2095-3941.2019.0347openalex-snapshot

Epigenetic N6-methyladenosine modification of RNA and DNA regulates cancer

inferred← citeshttps://doi.org/10.21203/rs.3.rs-4864013/v1openalex-snapshot

Investigating the hub genes and genetic basis regulating fatty acid metabolictraits in chicken breast muscle based on combined genomic and transcriptomic approaches

inferred← citeshttps://doi.org/10.2139/ssrn.5006215openalex-snapshot

The E3 Ubiquitin Ligase Trip12 Attenuates Wnt9a/Fzd9b Signaling During Hematopoietic Stem Cell Development

inferred← citeshttps://doi.org/10.32604/biocell.2023.026698openalex-snapshot

DNA methylation as a mediator of epigenetic regulation in the pathogenesis and precision medicine of osteoarthritis: An updated review

inferred← citeshttps://doi.org/10.3389/fcell.2021.663208openalex-snapshot

Epigenetic Regulation in Hydra: Conserved and Divergent Roles

inferred← citeshttps://doi.org/10.3389/fcell.2023.1116805openalex-snapshot

Epigenetic reprogramming in cancer: From diagnosis to treatment

inferred← citeshttps://doi.org/10.3389/fgene.2021.657171openalex-snapshot

N6-Methyladenine in Eukaryotic DNA: Tissue Distribution, Early Embryo Development, and Neuronal Toxicity

inferred← citeshttps://doi.org/10.3389/fgene.2022.914404openalex-snapshot

DNA N6-Methyladenine Modification in Eukaryotic Genome

inferred← citeshttps://doi.org/10.3389/fimmu.2021.626418openalex-snapshot

Regulation of B Lymphocyte Development by Histone H2A Deubiquitinase BAP1

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1353138openalex-snapshot

B-cell intrinsic regulation of antibody mediated immunity by histone H2A deubiquitinase BAP1

inferred← citeshttps://doi.org/10.3389/fimmu.2024.1482728openalex-snapshot

Autoimmune disease: a view of epigenetics and therapeutic targeting

inferred← citeshttps://doi.org/10.3389/fmicb.2024.1286822openalex-snapshot

Characterization of winged helix domain fusion endonucleases as N6-methyladenine-dependent type IV restriction systems

inferred← citeshttps://doi.org/10.3389/fonc.2023.1153463openalex-snapshot

The role of demethylase AlkB homologs in cancer

inferred← citeshttps://doi.org/10.3389/fonc.2023.1290330openalex-snapshot

Epigenetic targeting of autophagy for cancer: DNA and RNA methylation

inferred← citeshttps://doi.org/10.3390/ani13030446openalex-snapshot

The Characterization and Differential Analysis of m6A Methylation in Hycole Rabbit Muscle and Adipose Tissue and Prediction of Regulatory Mechanism about Intramuscular Fat

inferred← citeshttps://doi.org/10.3390/biology14050461openalex-snapshot

Cross-Kingdom DNA Methylation Dynamics: Comparative Mechanisms of 5mC/6mA Regulation and Their Implications in Epigenetic Disorders

inferred← citeshttps://doi.org/10.3390/cimb46090622openalex-snapshot

Dealkylation of Macromolecules by Eukaryotic α-Ketoglutarate-Dependent Dioxygenases from the AlkB-like Family

inferred← citeshttps://doi.org/10.3390/epigenomes3030017openalex-snapshot

The Dynamic Partnership of Polycomb and Trithorax in Brain Development and Diseases

inferred← citeshttps://doi.org/10.3390/genes16070793openalex-snapshot

A Genome-Wide Association Study of Anti-Müllerian Hormone (AMH) Levels in Samoan Women

inferred← citeshttps://doi.org/10.3390/ijms21228515openalex-snapshot

E3 Ubiquitin Ligase TRIP12: Regulation, Structure, and Physiopathological Functions

inferred← citeshttps://doi.org/10.3390/ijms23115950openalex-snapshot

Molecular Classification and Overcoming Therapy Resistance for Acute Myeloid Leukemia with Adverse Genetic Factors

inferred← citeshttps://doi.org/10.3390/ijms24043368openalex-snapshot

Structures of MPND Reveal the Molecular Recognition of Nucleosomes

inferred← citeshttps://doi.org/10.3390/ijms24043468openalex-snapshot

CRISPR-Cas9-Mediated Mutation of Methyltransferase METTL4 Results in Embryonic Defects in Silkworm Bombyx mori

inferred← citeshttps://doi.org/10.3390/ijms24043727openalex-snapshot

The Immuno-Oncology and Genomic Aspects of DNA-Hypomethylating Therapeutics in Acute Myeloid Leukemia

inferred← citeshttps://doi.org/10.3390/ijms25020686openalex-snapshot

Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A

inferred← citeshttps://doi.org/10.3390/ijms26115349openalex-snapshot

The Role of Methylation Modification in Neural Injury and Repair

inferred← citeshttps://doi.org/10.3390/ijms262411799openalex-snapshot

8-Oxoguanine: A Lesion, an Epigenetic Mark, or a Molecular Signal?

inferred← citeshttps://doi.org/10.3390/plants9020247openalex-snapshot

DNA N6-Methyladenine Modification in Plant Genomes—A Glimpse into Emerging Epigenetic Code

inferred← citeshttps://doi.org/10.3390/w14223595openalex-snapshot

ALKBH4 Stabilization Is Required for Arsenic-Induced 6mA DNA Methylation Inhibition, Keratinocyte Malignant Transformation, and Tumorigenicity

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062462openalex-snapshot

Additional file 1 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062465openalex-snapshot

Additional file 2 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062468openalex-snapshot

Additional file 3 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062471openalex-snapshot

Additional file 4 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062474openalex-snapshot

Additional file 5 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062477openalex-snapshot

Additional file 6 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062480openalex-snapshot

Additional file 7 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062483openalex-snapshot

Additional file 8 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.6084/m9.figshare.24062486openalex-snapshot

Additional file 9 of A DNA adenine demethylase impairs PRC2-mediated repression of genes marked by a specific chromatin signature

inferred← citeshttps://doi.org/10.61797/ijbic.v2i2.234openalex-snapshot

A review on Epigenome Editing using CRISPR-based Tools to Rejuvenate Skin Tissues

inferred← citeshttps://doi.org/10.70675/0c0f818fz10b0z42d5zbea1zde77534d9ffaopenalex-snapshot

Etude du rôle et des modes d’action de l’enzyme épigénétique TET chez la drosophile

inferred← citeshttps://doi.org/10.70675/2940ddd8z8031z4332z8a4az40015df9c667openalex-snapshot

Régulation et fonctions de l'E3 ubiquitine ligase TRIP12 au cours du cycle cellulaire

inferred← citeshttps://doi.org/10.7150/jca.89271openalex-snapshot

ALKBH1 rs2267755 C>T polymorphism decreases neuroblastoma risk in Chinese children

inferred← citeshttps://doi.org/10.7554/elife.101626openalex-snapshot

N6-methyladenosine in DNA promotes genome stability

inferred← citeshttps://doi.org/10.7554/elife.101626.1openalex-snapshot

N6-methyladenosine in DNA promotes genome stability

inferred← citeshttps://doi.org/10.7554/elife.101626.2openalex-snapshot

N6-methyladenosine in DNA promotes genome stability

inferred← citeshttps://doi.org/10.7554/elife.101626.3openalex-snapshot

N6-methyladenosine in DNA promotes genome stability

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