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Hearts and bones: Shared regulatory mechanisms in heart valve, cartilage, tendon, and bone development
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/jama.262.4.523openalex-snapshot
Association of mitral valve prolapse and systemic abnormalities of connective tissue. A phenotypic continuum
inferredcites →https://doi.org/10.1002/(sici)1097-0177(199710)210:2<130::aid-aja6>3.0.co;2-hopenalex-snapshot
Developmental expression of perlecan during murine embryogenesis
inferredcites →https://doi.org/10.1002/(sici)1097-0177(199803)211:3<248::aid-aja6>3.0.co;2-hopenalex-snapshot
Expression of type VI collagen in the developing mouse heart
inferredcites →https://doi.org/10.1002/aja.1001480108openalex-snapshot
Structural development of endocardial cushions
inferredcites →https://doi.org/10.1002/aja.1002000407openalex-snapshot
Elastic extracellular matrix of the embryonic chick heart: An immunohistological study using laser confocal microscopy
inferredcites →https://doi.org/10.1002/aja.1002040106openalex-snapshot
Developmental pattern of expression of the mouse α1(XI) collagen gene (Col11a1)
inferredcites →https://doi.org/10.1002/ajmg.10774openalex-snapshot
Molecular basis of vertebrate limb patterning
inferredcites →https://doi.org/10.1002/ajmg.1320240302openalex-snapshot
Prevalence of mitral‐valve prolapse in the Stickler syndrome
inferredcites →https://doi.org/10.1002/ajmg.1320470409openalex-snapshot
Williams syndrome: Autosomal dominant inheritance
inferredcites →https://doi.org/10.1002/ajmg.a.10619openalex-snapshot
Prevalence of mitral valve prolapse in Stickler syndrome
inferredcites →https://doi.org/10.1002/ajmg.c.30068openalex-snapshot
Recent progress towards a molecular understanding of Marfan syndrome
inferredcites →https://doi.org/10.1002/ar.10129openalex-snapshot
Survey of fibroblast growth factor expression during chick organogenesis
inferredcites →https://doi.org/10.1002/ar.1092430311openalex-snapshot
Atrioventricular valves of the mouse: III. Collagenous skeleton and myotendinous junction
inferredcites →https://doi.org/10.1002/dvdy.10418openalex-snapshot
Molecular markers of cardiac endocardial cushion development
inferredcites →https://doi.org/10.1002/dvdy.10481openalex-snapshot
Signals regulating tendon formation during chick embryonic development
inferredcites →https://doi.org/10.1002/dvdy.20051openalex-snapshot
Development of heart valve leaflets and supporting apparatus in chicken and mouse embryos
inferredcites →https://doi.org/10.1002/dvdy.20092openalex-snapshot
MAP kinase activation in avian cardiovascular development
inferredcites →https://doi.org/10.1002/gene.10050openalex-snapshot
Conditional inactivation of Sox9: A mouse model for campomelic dysplasia
inferredcites →https://doi.org/10.1002/jcb.20211openalex-snapshot
Multiple functions of BMPs in chondrogenesis
inferredcites →https://doi.org/10.1002/path.850openalex-snapshot
Expression of MMP2, MMP9, MT1-MMP, TIMP1, and TIMP2 mRNA in valvular lesions of the heart
inferredcites →https://doi.org/10.1006/bbrc.1998.8697openalex-snapshot
Severe Osteoporosis in Mice Lacking Osteoclastogenesis Inhibitory Factor/Osteoprotegerin
inferredcites →https://doi.org/10.1006/dbio.1996.8487openalex-snapshot
SOX9 Binds DNA, Activates Transcription, and Coexpresses with Type II Collagen during Chondrogenesis in the Mouse
inferredcites →https://doi.org/10.1006/dbio.1997.8824openalex-snapshot
Endogenous and Ectopic Expression ofnogginSuggests a Conserved Mechanism for Regulation of BMP Function during Limb and Somite Patterning
inferredcites →https://doi.org/10.1006/dbio.1998.9001openalex-snapshot
TheCspg2Gene, Disrupted in thehdfMutant, Is Required for Right Cardiac Chamber and Endocardial Cushion Formation
inferredcites →https://doi.org/10.1006/dbio.2002.0707openalex-snapshot
Fgf4 Positively Regulates scleraxis and Tenascin Expression in Chick Limb Tendons
inferredcites →https://doi.org/10.1007/bf00187179openalex-snapshot
Immunohistological and ultrastructural study of the developing tendons of the avian foot
inferredcites →https://doi.org/10.1007/s00109-003-0456-5openalex-snapshot
Form and function of developing heart valves: coordination by extracellular matrix and growth factor signaling
inferredcites →https://doi.org/10.1016/0002-8703(95)90397-6openalex-snapshot
Abnormalities in elastic fibers and other connective-tissue components of floppy mitral valve
inferredcites →https://doi.org/10.1016/0003-4975(95)00263-kopenalex-snapshot
Aortic valve cusp microstructure: The role of elastin
inferredcites →https://doi.org/10.1016/0092-8674(84)90514-2openalex-snapshot
Embryonic lethal mutation in mouse collagen I gene causes rupture of blood vessels and is associated with erythropoietic and mesenchymal cell death
inferredcites →https://doi.org/10.1016/0092-8674(95)90492-1openalex-snapshot
A fibrillar collagen gene, Col11a1, is essential for skeletal morphogenesis
inferredcites →https://doi.org/10.1016/0922-3371(89)90740-5openalex-snapshot
The extracellular matrix architecture relating to myotendinous pattern formation in the distal part of the developing chick limb: An ultrastructural, histochemical and immunocytochemical analysis
inferredcites →https://doi.org/10.1016/j.bbrc.2005.06.189openalex-snapshot
Limb chondrogenesis is compromised in the versican deficient hdf mouse
inferredcites →https://doi.org/10.1016/j.carpath.2005.03.005openalex-snapshot
Cardiac valves and valvular pathology
inferredcites →https://doi.org/10.1016/j.cell.2005.02.006openalex-snapshot
Longevity and Lineages: Toward the Integrative Biology of Degenerative Diseases in Heart, Muscle, and Bone
inferredcites →https://doi.org/10.1016/j.cytogfr.2004.06.004openalex-snapshot
The molecular triad OPG/RANK/RANKL: involvement in the orchestration of pathophysiological bone remodeling
inferredcites →https://doi.org/10.1016/j.jacc.2004.03.050openalex-snapshot
Bicuspid aortic valve is heritable
inferredcites →https://doi.org/10.1016/j.prp.2005.02.001openalex-snapshot
CD34+ fibrocytes in normal mitral valves and myxomatous mitral valve degeneration
inferredcites →https://doi.org/10.1016/j.ydbio.2004.01.045openalex-snapshot
Bone morphogenetic protein-2 can mediate myocardial regulation of atrioventricular cushion mesenchymal cell formation in mice
inferredcites →https://doi.org/10.1016/j.ydbio.2005.12.042openalex-snapshot
BMP and FGF regulatory pathways control cell lineage diversification of heart valve precursor cells
inferredcites →https://doi.org/10.1016/j.ydbio.2006.01.017openalex-snapshot
NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K
inferredcites →https://doi.org/10.1016/j.ymgme.2003.07.004openalex-snapshot
Control of endocardial cushion and cardiac valve maturation by BMP signaling pathways
inferredcites →https://doi.org/10.1016/s0003-4975(03)01584-4openalex-snapshot
Fibrillin and other matrix proteins in mitral valve prolapse syndrome
inferredcites →https://doi.org/10.1016/s0012-1606(03)00066-6openalex-snapshot
Analysis of the molecular cascade responsible for mesodermal limb chondrogenesis: sox genes and BMP signaling
inferredcites →https://doi.org/10.1016/s0012-1606(03)00099-xopenalex-snapshot
Fibroblast growth factor (FGF)-4 can induce proliferation of cardiac cushion mesenchymal cells during early valve leaflet formation
inferredcites →https://doi.org/10.1016/s0021-9258(18)51455-1openalex-snapshot
Glycine to serine substitution in the triple helical domain of pro-α 1 (II) collagen results in a lethal perinatal form of short-limbed dwarfism
inferredcites →https://doi.org/10.1016/s0021-9258(18)68776-9openalex-snapshot
Ehlers-Danlos syndrome type IV: a multi-exon deletion in one of the two COL3A1 alleles affecting structure, stability, and processing of type III procollagen.
inferredcites →https://doi.org/10.1016/s0021-9290(97)00122-xopenalex-snapshot
The role of elastin in aortic valve mechanics
inferredcites →https://doi.org/10.1016/s0074-7696(05)43005-3openalex-snapshot
Cell Biology of Cardiac Cushion Development
inferredcites →https://doi.org/10.1016/s0735-1097(02)01886-7openalex-snapshot
The incidence of congenital heart disease
inferredcites →https://doi.org/10.1016/s0925-4773(02)00249-6openalex-snapshot
Expression of Sox8, Sox9 and Sox10 in the developing valves and autonomic nerves of the embryonic heart
inferredcites →https://doi.org/10.1016/s0959-437x(02)00339-8openalex-snapshot
Developmental regulation of somite derivatives: muscle, cartilage and tendon
inferredcites →https://doi.org/10.1016/s1054-8807(99)00004-6openalex-snapshot
Ultrastructure Abnormalities in Proteoglycans, Collagen Fibrils, and Elastic Fibers in Normal and Myxomatous Mitral Valve Chordae Tendineae
inferredcites →https://doi.org/10.1016/s1534-5807(02)00157-0openalex-snapshot
Reaching a Genetic and Molecular Understanding of Skeletal Development
inferredcites →https://doi.org/10.1016/s1534-5807(02)00369-6openalex-snapshot
Induction and Activation of the Transcription Factor NFATc1 (NFAT2) Integrate RANKL Signaling in Terminal Differentiation of Osteoclasts
inferredcites →https://doi.org/10.1023/b:abme.0000032460.97278.e9openalex-snapshot
Relationship Between Collagen Fibrils, Glycosaminoglycans, and Stress Relaxation in Mitral Valve Chordae Tendineae
inferredcites →https://doi.org/10.1038/15537openalex-snapshot
Perlecan is essential for cartilage and cephalic development
inferredcites →https://doi.org/10.1038/16852openalex-snapshot
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
inferredcites →https://doi.org/10.1038/32419openalex-snapshot
Role of the NF-ATc transcription factor in morphogenesis of cardiac valves and septum
inferredcites →https://doi.org/10.1038/32426openalex-snapshot
The transcription factor NF-ATc is essential for cardiac valve formation
inferredcites →https://doi.org/10.1038/352330a0openalex-snapshot
Linkage of Marfan syndrome and a phenotypically related disorder to two different fibrillin genes
inferredcites →https://doi.org/10.1038/372525a0openalex-snapshot
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related gene
inferredcites →https://doi.org/10.1038/6016openalex-snapshot
Mice lacking link protein develop dwarfism and craniofacial abnormalities
inferredcites →https://doi.org/10.1038/82638openalex-snapshot
Perlecan, the major proteoglycan of basement membranes, is altered in patients with Schwartz-Jampel syndrome (chondrodystrophic myotonia)
inferredcites →https://doi.org/10.1038/8792openalex-snapshot
Sox9 is required for cartilage formation
inferredcites →https://doi.org/10.1038/eye.1994.153openalex-snapshot
Stickler syndrome: Correlation between vitreoretinal phenotypes and linkage to COL 2A1
inferredcites →https://doi.org/10.1038/nature01658openalex-snapshot
Osteoclast differentiation and activation
inferredcites →https://doi.org/10.1038/nature03940openalex-snapshot
Mutations in NOTCH1 cause aortic valve disease
inferredcites →https://doi.org/10.1038/ng0697-174openalex-snapshot
SOX9 directly regulates the type-ll collagen gene
inferredcites →https://doi.org/10.1038/ng0993-11openalex-snapshot
Hemizygosity at the elastin locus in a developmental disorder, Williams syndrome
inferredcites →https://doi.org/10.1038/ng0997-104openalex-snapshot
Tenascin–X deficiency is associated with Ehlers–Danlos syndrome
inferredcites →https://doi.org/10.1038/ng1059openalex-snapshot
Nf1 has an essential role in endothelial cells
inferredcites →https://doi.org/10.1038/ng772openalex-snapshot
Mutations in PTPN11, encoding the protein tyrosine phosphatase SHP-2, cause Noonan syndrome
inferredcites →https://doi.org/10.1038/nm1084openalex-snapshot
Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation
inferredcites →https://doi.org/10.1056/nejmoa002939openalex-snapshot
A Recessive Form of the Ehlers–Danlos Syndrome Caused by Tenascin-X Deficiency
inferredcites →https://doi.org/10.1073/pnas.0401711101openalex-snapshot
Essential role of Sox9 in the pathway that controls formation of cardiac valves and septa
inferredcites →https://doi.org/10.1073/pnas.111092198openalex-snapshot
Haploinsufficiency of Sox9 results in defective cartilage primordia and premature skeletal mineralization
inferredcites →https://doi.org/10.1073/pnas.88.15.6624openalex-snapshot
Stop codon in the procollagen II gene (COL2A1) in a family with the Stickler syndrome (arthro-ophthalmopathy).
inferredcites →https://doi.org/10.1073/pnas.88.17.7640openalex-snapshot
Expression of a partially deleted gene of human type II procollagen (COL2A1) in transgenic mice produces a chondrodysplasia.
inferredcites →https://doi.org/10.1073/pnas.90.8.3226openalex-snapshot
A human vascular disorder, supravalvular aortic stenosis, maps to chromosome 7.
inferredcites →https://doi.org/10.1073/pnas.94.13.6943openalex-snapshot
Dwarfism and age-associated spinal degeneration of heterozygote cmd mice defective in aggrecan
inferredcites →https://doi.org/10.1073/pnas.94.5.1852openalex-snapshot
Type III collagen is crucial for collagen I fibrillogenesis and for normal cardiovascular development
inferredcites →https://doi.org/10.1073/pnas.95.23.13453openalex-snapshot
Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
inferredcites →https://doi.org/10.1073/pnas.97.4.1566openalex-snapshot
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism
inferredcites →https://doi.org/10.1074/jbc.273.24.14998openalex-snapshot
Chondrocyte-specific Enhancer Elements in the Col11a2 Gene Resemble the Col2a1 Tissue-specific Enhancer
inferredcites →https://doi.org/10.1074/jbc.274.2.981openalex-snapshot
Cutis Laxa Arising from Frameshift Mutations in Exon 30 of the Elastin Gene (ELN)
inferredcites →https://doi.org/10.1074/jbc.275.17.12712openalex-snapshot
Identification of an Enhancer Sequence within the First Intron Required for Cartilage-specific Transcription of the α2(XI) Collagen Gene
inferredcites →https://doi.org/10.1074/jbc.m213067200openalex-snapshot
The Calcineurin/Nuclear Factor of Activated T Cells Signaling Pathway Regulates Osteoclastogenesis in RAW264.7 Cells
inferredcites →https://doi.org/10.1074/jbc.m406786200openalex-snapshot
SOX9-dependent and -independent Transcriptional Regulation of Human Cartilage Link Protein
inferredcites →https://doi.org/10.1074/jbc.m408795200openalex-snapshot
Essential Role of p38 Mitogen-activated Protein Kinase in Cathepsin K Gene Expression during Osteoclastogenesis through Association of NFATc1 and PU.1
inferredcites →https://doi.org/10.1080/03008200290001302openalex-snapshot
Viscoelastic Properties of Self-Assembled Type I Collagen Fibers: Molecular Basis of Elastic and Viscous Behaviors
inferredcites →https://doi.org/10.1083/jcb.140.5.1159openalex-snapshot
The Tight Skin Mouse: Demonstration of Mutant Fibrillin-1 Production and Assembly into Abnormal Microfibrils
inferredcites →https://doi.org/10.1083/jcb.98.6.1926openalex-snapshot
Chick myotendinous antigen. I. A monoclonal antibody as a marker for tendon and muscle morphogenesis.
inferredcites →https://doi.org/10.1086/301789openalex-snapshot
Marshall Syndrome Associated with a Splicing Defect at the COL11A1 Locus
inferredcites →https://doi.org/10.1086/302859openalex-snapshot
Classical Ehlers-Danlos Syndrome Caused by a Mutation in Type I Collagen
inferredcites →https://doi.org/10.1086/444401openalex-snapshot
A Mutation in the Variable Repeat Region of the Aggrecan Gene (AGC1) Causes a Form of Spondyloepiphyseal Dysplasia Associated with Severe, Premature Osteoarthritis
inferredcites →https://doi.org/10.1093/eurheartj/ehi248openalex-snapshot
Extracellular matrix remodelling in human aortic valve disease: the role of matrix metalloproteinases and their tissue inhibitors
inferredcites →https://doi.org/10.1097/00003086-200110001-00004openalex-snapshot
Composition and Structure of Articular Cartilage
inferredcites →https://doi.org/10.1101/gad.1017802openalex-snapshot
The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6
inferredcites →https://doi.org/10.1101/gad.12.9.1260openalex-snapshot
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification
inferredcites →https://doi.org/10.1111/j.1749-6632.1996.tb56300.xopenalex-snapshot
Stickler Syndrome Type 2 and Linkage to the COL11A1 Genea
inferredcites →https://doi.org/10.1126/science.2543071openalex-snapshot
Identification of the Molecular Defect in a Family with Spondyloepiphyseal Dysplasia
inferredcites →https://doi.org/10.1126/science.273.5279.1236openalex-snapshot
Pycnodysostosis, a Lysosomal Disease Caused by Cathepsin K Deficiency
inferredcites →https://doi.org/10.1126/science.293.5535.1670openalex-snapshot
UDP-Glucose Dehydrogenase Required for Cardiac Valve Formation in Zebrafish
inferredcites →https://doi.org/10.1128/mcb.17.4.2336openalex-snapshot
SOX9 Is a Potent Activator of the Chondrocyte-Specific Enhancer of the Proα1(II) Collagen Gene
inferredcites →https://doi.org/10.1136/jmg.22.3.187openalex-snapshot
Exclusion of the alpha 1(II) cartilage collagen gene as the mutant locus in type IA osteogenesis imperfecta.
inferredcites →https://doi.org/10.1136/jmg.40.1.34openalex-snapshot
In frame fibrillin-1 gene deletion in autosomal dominant Weill-Marchesani syndrome: Figure 1
inferredcites →https://doi.org/10.1152/physiol.00035.2005openalex-snapshot
Ras-Related Signaling Pathways in Valve Development: Ebb and Flow
inferredcites →https://doi.org/10.1159/000079779openalex-snapshot
The Epidemiology of Valvular Heart Diseases: The Problem Is Growing
inferredcites →https://doi.org/10.1159/000147166openalex-snapshot
Histochemical and Ultrastructural Changes in the Extracellular Matrix of the Developing Chick Semilunar Heart Valves
inferredcites →https://doi.org/10.1161/01.cir.0000070591.21548.69openalex-snapshot
Human Aortic Valve Calcification Is Associated With an Osteoblast Phenotype
inferredcites →https://doi.org/10.1161/01.cir.103.11.1522openalex-snapshot
Bone Formation and Inflammation in Cardiac Valves
inferredcites →https://doi.org/10.1161/01.cir.52.4.651openalex-snapshot
Aortic root dilatation and mitral valve prolapse in Marfan's syndrome: an ECHOCARDIOgraphic study.
inferredcites →https://doi.org/10.1161/01.cir.53.4.651openalex-snapshot
Mitral valve prolapse in children: a problem defined by real-time cross-sectional echocardiography.
inferredcites →https://doi.org/10.1161/01.hyp.0000164580.39991.3dopenalex-snapshot
Structural and Genetic Bases of Arterial Stiffness
inferredcites →https://doi.org/10.1161/01.res.0000026056.81424.daopenalex-snapshot
Hyperplastic Conotruncal Endocardial Cushions and Transposition of Great Arteries in Perlecan-Null Mice
inferredcites →https://doi.org/10.1161/01.res.0000136520.07995.aaopenalex-snapshot
Valvular Myofibroblast Activation by Transforming Growth Factor-β
inferredcites →https://doi.org/10.1161/01.res.0000141146.95728.daopenalex-snapshot
Heart Valve Development
inferredcites →https://doi.org/10.1161/01.res.0000141429.13560.cbopenalex-snapshot
Lineage and Morphogenetic Analysis of the Cardiac Valves
inferredcites →https://doi.org/10.1161/01.res.0000185326.04010.9fopenalex-snapshot
Heart Valve Tissue Engineering
inferredcites →https://doi.org/10.1161/01.res.0000186194.06514.b0openalex-snapshot
Noonan Syndrome Mutation Q79R in Shp2 Increases Proliferation of Valve Primordia Mesenchymal Cells via Extracellular Signal–Regulated Kinase 1/2 Signaling
inferredcites →https://doi.org/10.1161/01.res.77.1.1openalex-snapshot
Molecular Regulation of Atrioventricular Valvuloseptal Morphogenesis
inferredcites →https://doi.org/10.1161/01.res.83.5.523openalex-snapshot
Versican Expression Is Associated With Chamber Specification, Septation, and Valvulogenesis in the Developing Mouse Heart
inferredcites →https://doi.org/10.1161/circulationaha.105.171600openalex-snapshot
Heart Disease and Stroke Statistics—2006 Update
inferredcites →https://doi.org/10.1161/hc4601.099489openalex-snapshot
Activated Interstitial Myofibroblasts Express Catabolic Enzymes and Mediate Matrix Remodeling in Myxomatous Heart Valves
inferredcites →https://doi.org/10.1172/jci111082openalex-snapshot
Restriction fragment length polymorphism associated with the pro alpha 2(I) gene of human type I procollagen. Application to a family with an autosomal dominant form of osteogenesis imperfecta.
inferredcites →https://doi.org/10.1172/jci200419657openalex-snapshot
Critical roles of c-Jun signaling in regulation of NFAT family and RANKL-regulated osteoclast differentiation
inferredcites →https://doi.org/10.1172/jci200422715openalex-snapshot
TGF-β–dependent pathogenesis of mitral valve prolapse in a mouse model of Marfan syndrome
inferredcites →https://doi.org/10.1172/jci200423701openalex-snapshot
Marfan syndrome and mitral valve prolapse
inferredcites →https://doi.org/10.1172/jci4487openalex-snapshot
Novel arterial pathology in mice and humans hemizygous for elastin.
inferredcites →https://doi.org/10.1242/dev.01275openalex-snapshot
FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression
inferredcites →https://doi.org/10.1242/dev.01699openalex-snapshot
Feedback interactions between MKP3 and ERK MAP kinase controlscleraxisexpression and the specification of rib progenitors in the developing chick somite
inferredcites →https://doi.org/10.1242/dev.01970openalex-snapshot
Genetic and cellular analyses of zebrafish atrioventricular cushion and valve development
inferredcites →https://doi.org/10.1242/dev.02156openalex-snapshot
Bmp2 is essential for cardiac cushion epithelial-mesenchymal transition and myocardial patterning
inferredcites →https://doi.org/10.1242/dev.125.20.4019openalex-snapshot
Muscle and tendon morphogenesis in the avian hind limb
inferredcites →https://doi.org/10.1242/dev.126.19.4317openalex-snapshot
Dual role of the basic helix-loop-helix transcription factor scleraxis in mesoderm formation and chondrogenesis during mouse embryogenesis
inferredcites →https://doi.org/10.1242/dev.128.19.3855openalex-snapshot
Analysis of the tendon cell fate using Scleraxis, a specific marker for tendons and ligaments
inferredcites →https://doi.org/10.1359/jbmr.1999.14.10.1654openalex-snapshot
Cathepsin K Knockout Mice Develop Osteopetrosis Due to a Deficit in Matrix Degradation but Not Demineralization
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/adfm.202108057openalex-snapshot
Hylozoic by Design: Converging Material and Biological Complexities for Cell‐Driven Living Materials with 4D Behaviors
inferred← citeshttps://doi.org/10.1002/adma.201906423openalex-snapshot
From Shape to Function: The Next Step in Bioprinting
inferred← citeshttps://doi.org/10.1002/ar.23911openalex-snapshot
Filamin‐A as a Balance between Erk/Smad Activities During Cardiac Valve Development
inferred← citeshttps://doi.org/10.1002/ar.23913openalex-snapshot
Dynamic Expression Profiles of Sox9 in Embryonic, Post Natal, and Adult Heart Valve Cell Populations
inferred← citeshttps://doi.org/10.1002/ar.24010openalex-snapshot
Areas of Cartilaginous and Osseous Metaplasia After Experimental Myocardial Infarction in Rats
inferred← citeshttps://doi.org/10.1002/ar.25041openalex-snapshot
Heart morphology during the embryonic development of Podocnemis unifilis Trosquel 1948 (Testudines: Podocnemididae)
inferred← citeshttps://doi.org/10.1002/art.23237openalex-snapshot
Index to ring finger length ratio and the risk of osteoarthritis
inferred← citeshttps://doi.org/10.1002/art.30339openalex-snapshot
What makes the permanent articular cartilage permanent?
inferred← citeshttps://doi.org/10.1002/bdra.20799openalex-snapshot
Molecular and developmental mechanisms of congenital heart valve disease
inferred← citeshttps://doi.org/10.1002/bdra.20815openalex-snapshot
Notch signaling in cardiac valve development and disease
inferred← citeshttps://doi.org/10.1002/cphy.c150048openalex-snapshot
Heart Valve Biomechanics and Underlying Mechanobiology
inferred← citeshttps://doi.org/10.1002/cphy.c160020openalex-snapshot
Pathophysiology of Aortic Stenosis and Mitral Regurgitation
inferred← citeshttps://doi.org/10.1002/dvdy.20980openalex-snapshot
ColVa1 and ColXIa1 are required for myocardial morphogenesis and heart valve development
inferred← citeshttps://doi.org/10.1002/dvdy.21097openalex-snapshot
BMP and FGF regulatory pathways in semilunar valve precursor cells
inferred← citeshttps://doi.org/10.1002/dvdy.21719openalex-snapshot
Temporal and spatial expression of collagens during murine atrioventricular heart valve development and maintenance
inferred← citeshttps://doi.org/10.1002/dvdy.21933openalex-snapshot
Periostin promotes a fibroblastic lineage pathway in atrioventricular valve progenitor cells
inferred← citeshttps://doi.org/10.1002/dvdy.22702openalex-snapshot
Transforming growth factor Beta2 is required for valve remodeling during heart development
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2016.tb00724.xopenalex-snapshot
Heart Valve Biomechanics and Underlying Mechanobiology
inferred← citeshttps://doi.org/10.1002/j.2040-4603.2017.tb00762.xopenalex-snapshot
Pathophysiology of Aortic Stenosis and Mitral Regurgitation
inferred← citeshttps://doi.org/10.1002/jbmr.2903openalex-snapshot
Bone Mineral Density Is Positively Related to Carotid Intima-Media Thickness: Findings From a Population-Based Study in Adolescents and Premenopausal Women
inferred← citeshttps://doi.org/10.1002/jcb.22975openalex-snapshot
An autonomous BMP2 regulatory element in mesenchymal cells
inferred← citeshttps://doi.org/10.1002/jcp.22999openalex-snapshot
Human myxomatous mitral valve prolapse: Role of bone morphogenetic protein 4 in valvular interstitial cell activation
inferred← citeshttps://doi.org/10.1002/pd.2443openalex-snapshot
Identification of circulating placental mRNA in maternal blood of pregnancies affected with fetal congenital heart diseases at the second trimester of pregnancy: implications for early molecular screening
inferred← citeshttps://doi.org/10.1002/pd.4853openalex-snapshot
Maternal plasma mRNA species in fetal heart defects: a potential for molecular screening
inferred← citeshttps://doi.org/10.1007/978-1-4471-4429-8_36openalex-snapshot
Role of Bone Morphogenetic Proteins in Valvulogenesis
inferred← citeshttps://doi.org/10.1007/978-1-4899-7693-2_1openalex-snapshot
Oxidative Stress in Cardiac Valve Development
inferred← citeshttps://doi.org/10.1007/978-3-030-01993-8_10openalex-snapshot
Mechanical Mediation of Signaling Pathways in Heart Valve Development and Disease
inferred← citeshttps://doi.org/10.1007/978-3-030-01993-8_3openalex-snapshot
The Role of Proteoglycans and Glycosaminoglycans in Heart Valve Biomechanics
inferred← citeshttps://doi.org/10.1007/978-3-030-01993-8_9openalex-snapshot
Molecular and Cellular Developments in Heart Valve Development and Disease
inferred← citeshttps://doi.org/10.1007/978-3-030-18512-1_4-1openalex-snapshot
Heart Valve Bioengineering
inferred← citeshttps://doi.org/10.1007/978-3-030-42937-9_53-1openalex-snapshot
Congenital Mitral Valve Abnormalities
inferred← citeshttps://doi.org/10.1007/978-3-030-44211-8_4openalex-snapshot
Heart Valve Bioengineering
inferred← citeshttps://doi.org/10.1007/978-3-030-46725-8_3openalex-snapshot
Developmental Pathways and Aortic Valve Calcification
inferred← citeshttps://doi.org/10.1007/978-3-030-67947-7_9openalex-snapshot
Morphogenetic Aspects of Mitral Valve Development
inferred← citeshttps://doi.org/10.1007/978-3-030-80614-9_5openalex-snapshot
Proteoglycans and Diseases of Soft Tissues
inferred← citeshttps://doi.org/10.1007/978-3-030-80614-9_6openalex-snapshot
Growth Factor Roles in Soft Tissue Physiology and Pathophysiology
inferred← citeshttps://doi.org/10.1007/978-3-031-07563-6_53openalex-snapshot
Congenital Mitral Valve Abnormalities
inferred← citeshttps://doi.org/10.1007/978-94-007-7893-1_4openalex-snapshot
Proteoglycans and Diseases of Soft Tissues
inferred← citeshttps://doi.org/10.1007/978-94-007-7893-1_5openalex-snapshot
Advances in the Use of Growth Factors for Treatment of Disorders of Soft Tissues
inferred← citeshttps://doi.org/10.1007/s00018-011-0784-5openalex-snapshot
Periostin in fibrillogenesis for tissue regeneration: periostin actions inside and outside the cell
inferred← citeshttps://doi.org/10.1007/s00018-012-1197-9openalex-snapshot
Co-ordinating Notch, BMP, and TGF-β signaling during heart valve development
inferred← citeshttps://doi.org/10.1007/s00246-009-9616-xopenalex-snapshot
Transcriptional Regulation of Heart Valve Progenitor Cells
inferred← citeshttps://doi.org/10.1007/s00296-009-1217-8openalex-snapshot
Valvular heart disease in systemic lupus erythematosus and Jaccoud’s arthropathy
inferred← citeshttps://doi.org/10.1007/s00418-012-1022-4openalex-snapshot
The role of PKCε-dependent signaling for cardiac differentiation
inferred← citeshttps://doi.org/10.1007/s00439-006-0316-9openalex-snapshot
Evidence in favor of linkage to human chromosomal regions 18q, 5q and 13q for bicuspid aortic valve and associated cardiovascular malformations
inferred← citeshttps://doi.org/10.1007/s00441-007-0570-8openalex-snapshot
Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development
inferred← citeshttps://doi.org/10.1007/s00441-011-1241-3openalex-snapshot
Transforming growth factor beta signaling in adult cardiovascular diseases and repair
inferred← citeshttps://doi.org/10.1007/s10237-012-0448-xopenalex-snapshot
Development of fibroblast-seeded collagen gels under planar biaxial mechanical constraints: a biomechanical study
inferred← citeshttps://doi.org/10.1007/s11886-014-0487-2openalex-snapshot
Genetics of Valvular Heart Disease
inferred← citeshttps://doi.org/10.1007/s11886-018-0968-9openalex-snapshot
Calcific Aortic Valve Disease: a Developmental Biology Perspective
inferred← citeshttps://doi.org/10.1007/s12013-013-9606-8openalex-snapshot
Distinct Signaling Pathways Activated by “Extracellular” and “Intracellular” Serotonin in Heart Valve Development and Disease
inferred← citeshttps://doi.org/10.1007/s12024-026-01205-wopenalex-snapshot
The examination of the atrio-ventricular node region should be a routine practice in all cases of sudden unexpected death in infancy (SUDI) and childhood (SUDC)
inferred← citeshttps://doi.org/10.1007/s12265-011-9312-0openalex-snapshot
Progenitor Cells Confer Plasticity to Cardiac Valve Endothelium
inferred← citeshttps://doi.org/10.1016/b978-0-12-381332-9.00019-0openalex-snapshot
Signaling Pathways in Valve Formation
inferred← citeshttps://doi.org/10.1016/b978-0-12-387786-4.00006-3openalex-snapshot
Heart Valve Development, Maintenance, and Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-397166-1.00012-6openalex-snapshot
Physiological Actions of PTH and PTHrP IV
inferred← citeshttps://doi.org/10.1016/b978-0-12-405206-2.00001-6openalex-snapshot
Molecular Basis of Cardiac Development
inferred← citeshttps://doi.org/10.1016/b978-0-12-405206-2.00009-0openalex-snapshot
Calcific and Degenerative Heart Valve Disease
inferred← citeshttps://doi.org/10.1016/b978-0-12-814841-9.00026-9openalex-snapshot
Cardiovascular actions of parathyroid hormone/parathyroid hormone–related protein signaling
inferred← citeshttps://doi.org/10.1016/b978-0-323-05385-3.50021-0openalex-snapshot
Cardiovascular System
inferred← citeshttps://doi.org/10.1016/b978-0-323-06545-0.00054-6openalex-snapshot
The cardiovascular system
inferred← citeshttps://doi.org/10.1016/b978-0-323-35214-7.00050-0openalex-snapshot
Cardiovascular Development
inferred← citeshttps://doi.org/10.1016/b978-0-323-56711-4.00071-7openalex-snapshot
10.1016/b978-0-323-56711-4.00071-7
inferred← citeshttps://doi.org/10.1016/b978-1-4160-3479-7.10063-1openalex-snapshot
Cardiovascular Development
inferred← citeshttps://doi.org/10.1016/b978-1-4557-2794-0.00017-6openalex-snapshot
Cardiovascular System
inferred← citeshttps://doi.org/10.1016/b978-1-78242-301-0.00003-3openalex-snapshot
Growth factors for musculoskeletal tissue engineering
inferred← citeshttps://doi.org/10.1016/j.athoracsur.2008.02.027openalex-snapshot
Endothelial Expression of Bone Morphogenetic Protein Receptor Type 1a is Required for Atrioventricular Valve Formation
inferred← citeshttps://doi.org/10.1016/j.athoracsur.2018.06.034openalex-snapshot
The Transcriptional Signature of Growth in Human Fetal Aortic Valve Development
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2012.09.013openalex-snapshot
Embryological origin of the endocardium and derived valve progenitor cells: From developmental biology to stem cell-based valve repair
inferred← citeshttps://doi.org/10.1016/j.bbamcr.2016.03.004openalex-snapshot
Interplay between cardiac function and heart development
inferred← citeshttps://doi.org/10.1016/j.biocel.2009.10.003openalex-snapshot
Scleraxis and E47 cooperatively regulate the Sox9-dependent transcription
inferred← citeshttps://doi.org/10.1016/j.carpath.2010.06.010openalex-snapshot
Transcriptional regulation of heart valve development and disease
inferred← citeshttps://doi.org/10.1016/j.carpath.2012.02.011openalex-snapshot
Decreased and inactivated nuclear factor kappa B 1 (p50) in human degenerative calcified aortic valve
inferred← citeshttps://doi.org/10.1016/j.carpath.2012.11.001openalex-snapshot
Emerging pathogenic mechanisms in human myxomatous mitral valve: lessons from past and novel data
inferred← citeshttps://doi.org/10.1016/j.cellsig.2023.110929openalex-snapshot
Identification and functional coordination analysis of gene co-expression networks in different tissues of XBP1 cartilage-specific deficient mice
inferred← citeshttps://doi.org/10.1016/j.celrep.2018.02.066openalex-snapshot
TGF-ß Regulates Cathepsin Activation during Normal and Pathogenic Development
inferred← citeshttps://doi.org/10.1016/j.cels.2024.10.006openalex-snapshot
Systematic analysis identifies a connection between spatial and genomic variations of chromatin states
inferred← citeshttps://doi.org/10.1016/j.devcel.2009.06.017openalex-snapshot
Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis
inferred← citeshttps://doi.org/10.1016/j.diff.2012.04.001openalex-snapshot
Atrioventricular valve development: New perspectives on an old theme
inferred← citeshttps://doi.org/10.1016/j.diff.2026.100987openalex-snapshot
The regulation of endothelial-to-mesenchymal transition in endocardial cushion development: Signaling pathways and transcription factors
inferred← citeshttps://doi.org/10.1016/j.ijcard.2017.09.174openalex-snapshot
Reduced aggrecan expression affects cardiac outflow tract development in zebrafish and is associated with bicuspid aortic valve disease in humans
inferred← citeshttps://doi.org/10.1016/j.jacc.2018.09.089openalex-snapshot
Endothelial to Mesenchymal Transition in Cardiovascular Disease
inferred← citeshttps://doi.org/10.1016/j.jcpa.2008.06.001openalex-snapshot
Detection and Characterization of Chondroid Metaplasia in Canine Atrioventricular Valves
inferred← citeshttps://doi.org/10.1016/j.jtcvs.2009.11.006openalex-snapshot
In vivo monitoring of function of autologous engineered pulmonary valve
inferred← citeshttps://doi.org/10.1016/j.jvc.2011.12.001openalex-snapshot
Signaling pathways in mitral valve degeneration
inferred← citeshttps://doi.org/10.1016/j.jvc.2011.12.002openalex-snapshot
Static and cyclic tensile strain induce myxomatous effector proteins and serotonin in canine mitral valves
inferred← citeshttps://doi.org/10.1016/j.matbio.2012.01.001openalex-snapshot
Maladaptive matrix remodeling and regional biomechanical dysfunction in a mouse model of aortic valve disease
inferred← citeshttps://doi.org/10.1016/j.mehy.2013.05.017openalex-snapshot
Tgif1 and SnoN modified chondrocytes or stem cells for tendon–bone insertion regeneration
inferred← citeshttps://doi.org/10.1016/j.siny.2013.05.003openalex-snapshot
Environmental origins of congenital heart disease: The heart–placenta connection
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.09.024openalex-snapshot
Atrioventricular valve development during late embryonic and postnatal stages involves condensation and extracellular matrix remodeling
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.09.047openalex-snapshot
Tbx20 regulation of endocardial cushion cell proliferation and extracellular matrix gene expression
inferred← citeshttps://doi.org/10.1016/j.ydbio.2006.09.048openalex-snapshot
Periostin promotes atrioventricular mesenchyme matrix invasion and remodeling mediated by integrin signaling through Rho/PI 3-kinase
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.02.002openalex-snapshot
Sox9 is required for precursor cell expansion and extracellular matrix organization during mouse heart valve development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.07.041openalex-snapshot
Cartilage link protein 1 (Crtl1), an extracellular matrix component playing an important role in heart development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2007.12.028openalex-snapshot
BMP-2 induces cell migration and periostin expression during atrioventricular valvulogenesis
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.01.003openalex-snapshot
Periostin regulates atrioventricular valve maturation
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.02.006openalex-snapshot
Disruption of Smad4 in neural crest cells leads to mid-gestation death with pharyngeal arch, craniofacial and cardiac defects
inferred← citeshttps://doi.org/10.1016/j.ydbio.2008.02.037openalex-snapshot
Twist1 function in endocardial cushion cell proliferation, migration, and differentiation during heart valve development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2009.11.030openalex-snapshot
Wnt signaling in heart valve development and osteogenic gene induction
inferred← citeshttps://doi.org/10.1016/j.ydbio.2010.08.021openalex-snapshot
Twist1 promotes heart valve cell proliferation and extracellular matrix gene expression during development in vivo and is expressed in human diseased aortic valves
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.06.041openalex-snapshot
Altered versican cleavage in ADAMTS5 deficient mice; A novel etiology of myxomatous valve disease
inferred← citeshttps://doi.org/10.1016/j.ydbio.2011.08.022openalex-snapshot
Mmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.06.002openalex-snapshot
Pod1/Tcf21 is regulated by retinoic acid signaling and inhibits differentiation of epicardium-derived cells into smooth muscle in the developing heart
inferred← citeshttps://doi.org/10.1016/j.ydbio.2012.11.023openalex-snapshot
Fluid flow forces and rhoA regulate fibrous development of the atrioventricular valves
inferred← citeshttps://doi.org/10.1016/j.yexmp.2008.02.004openalex-snapshot
Osteoprotegerin/RANK/RANKL axis in cardiac remodeling due to immuno-inflammatory myocardial disease
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2010.12.005openalex-snapshot
Differential expression of cartilage and bone-related proteins in pediatric and adult diseased aortic valves
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2011.12.013openalex-snapshot
Differential activation of valvulogenic, chondrogenic, and osteogenic pathways in mouse models of myxomatous and calcific aortic valve disease
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.03.010openalex-snapshot
Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valves
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2013.10.007openalex-snapshot
Tgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2017.05.012openalex-snapshot
Effect of altered haemodynamics on the developing mitral valve in chick embryonic heart
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2020.03.013openalex-snapshot
Piezo1 is required for outflow tract and aortic valve development
inferred← citeshttps://doi.org/10.1016/j.yjmcc.2023.11.002openalex-snapshot
Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development
inferred← citeshttps://doi.org/10.1016/s0070-2153(08)00604-2openalex-snapshot
Chapter 4 Mouse Models of Congenital Cardiovascular Disease
inferred← citeshttps://doi.org/10.1017/s1431927610094365openalex-snapshot
Expression and Deposition of Fibrous Extracellular Matrix Proteins in Cardiac Valves during Chick Development
inferred← citeshttps://doi.org/10.1021/acsami.7b03281openalex-snapshot
Bioinspired Engineering of Poly(ethylene glycol) Hydrogels and Natural Protein Fibers for Layered Heart Valve Constructs
inferred← citeshttps://doi.org/10.1021/bi401284ropenalex-snapshot
FGF–FGFR Signaling Mediated through Glycosaminoglycans in Microtiter Plate and Cell-Based Microarray Platforms
inferred← citeshttps://doi.org/10.1021/cb400713vopenalex-snapshot
Divergent Differentiation of Skeletal Progenitors into Cartilage and Tendon: Lessons from the Embryonic Limb
inferred← citeshttps://doi.org/10.1038/s41467-026-71043-5openalex-snapshot
Formation of S- and Z-twist supramolecular micro-ropes by peptide stereoisomers
inferred← citeshttps://doi.org/10.1038/s41467-026-77008-yopenalex-snapshot
Hypoxia-activated scleraxis a mediates epicardial progenitor differentiation into a unique cardiac perivascular cell type
inferred← citeshttps://doi.org/10.1038/s41598-017-08185-6openalex-snapshot
Expression changes in pelvic organ prolapse: a systematic review and in silico study
inferred← citeshttps://doi.org/10.1038/s44318-026-00886-xopenalex-snapshot
Hox/Meis-dependent gene-regulatory transition underlies cardiopharyngeal neural crest diversification
inferred← citeshttps://doi.org/10.1038/srep00977openalex-snapshot
Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytes
inferred← citeshttps://doi.org/10.1073/pnas.1508399112openalex-snapshot
Spontaneous retrotransposon insertion into TNF 3′UTR causes heart valve disease and chronic polyarthritis
inferred← citeshttps://doi.org/10.1074/jbc.m109.014811openalex-snapshot
Transforming Growth Factors β Coordinate Cartilage and Tendon Differentiation in the Developing Limb Mesenchyme
inferred← citeshttps://doi.org/10.1074/jbc.m113.497727openalex-snapshot
Microfibril-associated Glycoprotein 2 (MAGP2) Loss of Function Has Pleiotropic Effects in Vivo
inferred← citeshttps://doi.org/10.1074/jbc.m610113200openalex-snapshot
Scleraxis and NFATc Regulate the Expression of the Pro-α1(I) Collagen Gene in Tendon Fibroblasts
inferred← citeshttps://doi.org/10.1074/jbc.m704723200openalex-snapshot
Bone Morphogenetic Protein 2 Functions via a Conserved Signaling Pathway Involving Wnt4 to Regulate Uterine Decidualization in the Mouse and the Human
inferred← citeshttps://doi.org/10.1080/09205063.2018.1429732openalex-snapshot
A human pericardium biopolymeric scaffold for autologous heart valve tissue engineering: cellular and extracellular matrix structure and biomechanical properties in comparison with a normal aortic heart valve
inferred← citeshttps://doi.org/10.1089/ars.2022.0166openalex-snapshot
Perish in the Attempt: Regulated Cell Death in Regenerative and Nonregenerative Tissue
inferred← citeshttps://doi.org/10.1089/ten.tea.2007.0292openalex-snapshot
Additive Effect of RGD Coating to Functionalized Titanium Surfaces on Human Osteoprogenitor Cell Adhesion and Spreading
inferred← citeshttps://doi.org/10.1089/ten.tea.2014.0189openalex-snapshot
Transforming Growth Factor Beta 1 Augments Calvarial Defect Healing and Promotes Suture Regeneration
inferred← citeshttps://doi.org/10.1093/cvr/cvu233openalex-snapshot
Loss of Krox20 results in aortic valve regurgitation and impaired transcriptional activation of fibrillar collagen genes
inferred← citeshttps://doi.org/10.1093/glycob/cwy003openalex-snapshot
Keratan sulfate, a complex glycosaminoglycan with unique functional capability
inferred← citeshttps://doi.org/10.1095/biolreprod.108.075697openalex-snapshot
Cloning of Complementary DNAs Encoding Structurally Related Homeoproteins from Preimplantation Mouse Embryos: Their Involvement in the Differentiation of Embryonic Stem Cells1
inferred← citeshttps://doi.org/10.1097/hco.0000000000000124openalex-snapshot
When should we prescribe high-dose folic acid to prevent congenital heart defects?
inferred← citeshttps://doi.org/10.1097/scs.0b013e3181843312openalex-snapshot
Bone Morphogenetic Protein 2 Therapy for Craniofacial Surgery
inferred← citeshttps://doi.org/10.1097/scs.0b013e318256657copenalex-snapshot
Safety and Efficacy of Recombinant Human Bone Morphogenetic Protein 2 on Cranial Defect Closure in the Pediatric Population
inferred← citeshttps://doi.org/10.1098/rsif.2009.0174openalex-snapshot
Melanocyte pigmentation stiffens murine cardiac tricuspid valve leaflet
inferred← citeshttps://doi.org/10.1100/tsw.2011.132openalex-snapshot
The Inter-Relationship of Periostin, TGFβ, and BMP in Heart Valve Development and Valvular Heart Diseases
inferred← citeshttps://doi.org/10.1101/2022.11.30.518511openalex-snapshot
Targeting of MMP-13 prevents aortic aneurysm formation in Marfan mice
inferred← citeshttps://doi.org/10.1101/2023.12.11.570452openalex-snapshot
Broad H3K4me3 Domain Is Associated with Spatial Coherence during Mammalian Embryonic Development
inferred← citeshttps://doi.org/10.1101/2025.05.09.652961openalex-snapshot
Concentration- and time-dependence of phosphorylation events stimulated by fibroblast growth factor-4 (FGF-4) in Rama 27 fibroblasts
inferred← citeshttps://doi.org/10.1101/cshperspect.a013912openalex-snapshot
How to Make a Heart Valve: From Embryonic Development to Bioengineering of Living Valve Substitutes
inferred← citeshttps://doi.org/10.1111/j.1755-148x.2008.00459.xopenalex-snapshot
Timeline and distribution of melanocyte precursors in the mouse heart
inferred← citeshttps://doi.org/10.1111/ped.15582openalex-snapshot
Increased incidence of mitral valve prolapse in children with pectus chest wall deformity
inferred← citeshttps://doi.org/10.1124/jpet.117.242503openalex-snapshot
Discovery and Preclinical Characterization of GSK1278863 (Daprodustat), a Small Molecule Hypoxia Inducible Factor–Prolyl Hydroxylase Inhibitor for Anemia
inferred← citeshttps://doi.org/10.1139/cjpp-2013-0489openalex-snapshot
A tale of 2 tissues: the overlapping role of scleraxis in tendons and the heart
inferred← citeshttps://doi.org/10.1139/y09-105openalex-snapshot
Emerging concepts in cardiac matrix biologyThis article is one of a selection of papers published in a special issue on Advances in Cardiovascular Research.
inferred← citeshttps://doi.org/10.1146/annurev-pathol-011110-130257openalex-snapshot
Mechanisms of Function and Disease of Natural and Replacement Heart Valves
inferred← citeshttps://doi.org/10.1146/annurev-physiol-012110-142145openalex-snapshot
Heart Valve Structure and Function in Development and Disease
inferred← citeshttps://doi.org/10.1146/annurev-physiol-022516-034001openalex-snapshot
Developmental Mechanisms of Aortic Valve Malformation and Disease
inferred← citeshttps://doi.org/10.1152/ajpheart.00209.2017openalex-snapshot
Hypoxia promotes primitive glycosaminoglycan-rich extracellular matrix composition in developing heart valves
inferred← citeshttps://doi.org/10.1152/ajpheart.00987.2011openalex-snapshot
Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00034.2020openalex-snapshot
Identification of a peripheral blood gene signature predicting aortic valve calcification
inferred← citeshttps://doi.org/10.1152/physiolgenomics.00115.2014openalex-snapshot
Comparative transcriptome profiling in human bicuspid aortic valve disease using RNA sequencing
inferred← citeshttps://doi.org/10.1152/physiolgenomics.90212.2008openalex-snapshot
Shared gene expression profiles in developing heart valves and osteoblast progenitor cells
inferred← citeshttps://doi.org/10.1152/physrev.00054.2009openalex-snapshot
Mitogen-Activated Protein Kinase Signaling in the Heart: Angels Versus Demons in a Heart-Breaking Tale
inferred← citeshttps://doi.org/10.1155/2013/320413openalex-snapshot
The Heart-Placenta Axis in the First Month of Pregnancy: Induction and Prevention of Cardiovascular Birth Defects
inferred← citeshttps://doi.org/10.1155/2016/7680701openalex-snapshot
Histochemical and Molecular Characterization of Spongiosal Cells in Native Tissue, Two- and Three-Dimensional Cultures of Rat Aortic Valve
inferred← citeshttps://doi.org/10.1159/000544776openalex-snapshot
Anatomy, Histology, Aetiology, Development and Functions of Cartilago Cordis: A Systematic Review
inferred← citeshttps://doi.org/10.1161/atvbaha.110.216184openalex-snapshot
Mitral Valve Endothelial Cells With Osteogenic Differentiation Potential
inferred← citeshttps://doi.org/10.1161/atvbaha.112.300388openalex-snapshot
Increased Dietary Intake of Vitamin A Promotes Aortic Valve Calcification In Vivo
inferred← citeshttps://doi.org/10.1161/atvbaha.113.302071openalex-snapshot
Conserved Transcriptional Regulatory Mechanisms in Aortic Valve Development and Disease
inferred← citeshttps://doi.org/10.1161/atvbaha.114.304579openalex-snapshot
Loss of β-Catenin Promotes Chondrogenic Differentiation of Aortic Valve Interstitial Cells
inferred← citeshttps://doi.org/10.1161/atvbaha.115.306091openalex-snapshot
Valve Endothelial Cell–Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification
inferred← citeshttps://doi.org/10.1161/circgenetics.112.962894openalex-snapshot
Genetic Basis of Familial Valvular Heart Disease
inferred← citeshttps://doi.org/10.1161/circresaha.108.177238openalex-snapshot
Scleraxis Is Required for Cell Lineage Differentiation and Extracellular Matrix Remodeling During Murine Heart Valve Formation In Vivo
inferred← citeshttps://doi.org/10.1161/circresaha.108.187252openalex-snapshot
Thar’s Tendons in Them Thar Valves!
inferred← citeshttps://doi.org/10.1161/circresaha.109.201566openalex-snapshot
Heart Valve Development
inferred← citeshttps://doi.org/10.1161/circresaha.109.213702openalex-snapshot
Reduced Sox9 Function Promotes Heart Valve Calcification Phenotypes In Vivo
inferred← citeshttps://doi.org/10.1161/circresaha.110.225318openalex-snapshot
The FGF-BMP Signaling Axis Regulates Outflow Tract Valve Primordium Formation by Promoting Cushion Neural Crest Cell Differentiation
inferred← citeshttps://doi.org/10.1161/circresaha.110.234237openalex-snapshot
Cell–Matrix Interactions in the Pathobiology of Calcific Aortic Valve Disease
inferred← citeshttps://doi.org/10.1161/circresaha.113.300155openalex-snapshot
Molecular and Cellular Aspects of Calcific Aortic Valve Disease
inferred← citeshttps://doi.org/10.1161/circresaha.123.323027openalex-snapshot
PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves
inferred← citeshttps://doi.org/10.1161/circulationaha.108.780031openalex-snapshot
Local Tenomodulin Absence, Angiogenesis, and Matrix Metalloproteinase Activation Are Associated With the Rupture of the Chordae Tendineae Cordis
inferred← citeshttps://doi.org/10.1161/circulationaha.108.805911openalex-snapshot
Evolving Concepts of Cardiac Valve Dynamics
inferred← citeshttps://doi.org/10.1161/jaha.121.023131openalex-snapshot
Spontaneous Degenerative Aortic Valve Disease in New Zealand Obese Mice
inferred← citeshttps://doi.org/10.1172/jci.insight.133019openalex-snapshot
Inappropriate cathepsin K secretion promotes its enzymatic activation driving heart and valve malformation
inferred← citeshttps://doi.org/10.1172/jci.insight.174417openalex-snapshot
ADAMTSL2 mutations determine the phenotypic severity in geleophysic dysplasia
inferred← citeshttps://doi.org/10.1172/jci40973openalex-snapshot
Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents
inferred← citeshttps://doi.org/10.1242/dev.125252openalex-snapshot
SOX9 modulates the expression of key transcription factors required for heart valve development
inferred← citeshttps://doi.org/10.1242/dev.180398openalex-snapshot
A cellular atlas of Pitx2-dependent cardiac development
inferred← citeshttps://doi.org/10.1242/dmm.008219openalex-snapshot
Excessive activity of cathepsin K is associated with cartilage defects in a zebrafish model of mucolipidosis II
inferred← citeshttps://doi.org/10.1369/0022155418824083openalex-snapshot
Non-pathological Chondrogenic Features of Valve Interstitial Cells in Normal Adult Zebrafish
inferred← citeshttps://doi.org/10.1369/0022155420952902openalex-snapshot
Aggrecan in Cardiovascular Development and Disease
inferred← citeshttps://doi.org/10.1371/journal.pone.0026769openalex-snapshot
Sox9 Transcriptionally Represses Spp1 to Prevent Matrix Mineralization in Maturing Heart Valves and Chondrocytes
inferred← citeshttps://doi.org/10.1371/journal.pone.0027743openalex-snapshot
Inhibitory Role of Notch1 in Calcific Aortic Valve Disease
inferred← citeshttps://doi.org/10.1371/journal.pone.0053183openalex-snapshot
A Subpopulation of Smooth Muscle Cells, Derived from Melanocyte-Competent Precursors, Prevents Patent Ductus Arteriosus
inferred← citeshttps://doi.org/10.1371/journal.pone.0057073openalex-snapshot
Mef2c Regulates Transcription of the Extracellular Matrix Protein Cartilage Link Protein 1 in the Developing Murine Heart
inferred← citeshttps://doi.org/10.1387/ijdb.130213ymopenalex-snapshot
Dual embryonic origin of the hyobranchial apparatus in the Mexican axolotl (Ambystoma mexicanum)
inferred← citeshttps://doi.org/10.14288/1.0220645openalex-snapshot
Analysis of transcriptional targets of SOX9 during embryonic heart valve development reveals a critical network of transcription factors
inferred← citeshttps://doi.org/10.14302/issn.2329-9487.jhc-12-102openalex-snapshot
Human Myxomatous Mitral Valves Exhibit Focal Expression of Cartilage-Related Proteins
inferred← citeshttps://doi.org/10.1586/eop.10.67openalex-snapshot
Pharmaceutical intervention for myopia control
inferred← citeshttps://doi.org/10.18926/amo/41320openalex-snapshot
Histone acetylation influences the activity of Sox9-related transcriptional complex.
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