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Detection and Structural Characterization of Glutathione-Trapped Reactive Metabolites Using Liquid Chromatography−High-Resolution Mass Spectrometry and Mass Defect Filtering

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/bms.1200220602openalex-snapshot
Mass spectrometry in the analysis of glutathione conjugates
inferredcites →https://doi.org/10.1002/rcm.2111openalex-snapshot
Accelerated throughput metabolic route screening in early drug discovery using high‐resolution liquid chromatography/quadrupole time‐of‐flight mass spectrometry and automated data analysis
inferredcites →https://doi.org/10.1002/rcm.2223openalex-snapshot
Application of stable isotope labeled glutathione and rapid scanning mass spectrometers in detecting and characterizing reactive metabolites
inferredcites →https://doi.org/10.1002/rcm.2996openalex-snapshot
MS E with mass defect filtering for in vitro and in vivo metabolite identification
inferredcites →https://doi.org/10.1006/taap.1994.1048openalex-snapshot
Cresol Isomers: Comparison of Toxic Potency in Rat Liver Slices
inferredcites →https://doi.org/10.1007/978-1-4613-4124-6openalex-snapshot
Biological Reactive Intermediates
inferredcites →https://doi.org/10.1007/pl00005298openalex-snapshot
Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine
inferredcites →https://doi.org/10.1016/j.jpba.2004.04.019openalex-snapshot
The development of a higher throughput reactive intermediate screening assay incorporating micro-bore liquid chromatography–micro-electrospray ionization–tandem mass spectrometry and glutathione ethyl ester as an in vitro conjugating agent
inferredcites →https://doi.org/10.1016/s0022-3565(24)37177-0openalex-snapshot
Neutrophil Cytotoxicity of the Chemically Reactive Metabolite(s) of Clozapine: Possible Role in Agranulocytosis
inferredcites →https://doi.org/10.1016/s1359-6446(03)02816-2openalex-snapshot
Screening for the potential of a drug candidate to cause idiosyncratic drug reactions
inferredcites →https://doi.org/10.1021/ac0518811openalex-snapshot
Performance Evaluation of a Hybrid Linear Ion Trap/Orbitrap Mass Spectrometer
inferredcites →https://doi.org/10.1021/tx0100237openalex-snapshot
Detection and Characterization of DNA Adducts of 3-Methylindole
inferredcites →https://doi.org/10.1021/tx034170bopenalex-snapshot
Drug−Protein Adducts: An Industry Perspective on Minimizing the Potential for Drug Bioactivation in Drug Discovery and Development
inferredcites →https://doi.org/10.1021/tx049741uopenalex-snapshot
Negative Ion Tandem Mass Spectrometry for the Detection of Glutathione Conjugates
inferredcites →https://doi.org/10.1021/tx600277yopenalex-snapshot
Screening and Identification of GSH-Trapped Reactive Metabolites Using Hybrid Triple Quadruple Linear Ion Trap Mass Spectrometry
inferredcites →https://doi.org/10.1021/tx950120yopenalex-snapshot
Bioactivation of a Toxic Metabolite of Valproic Acid, (E)-2-Propyl-2,4-pentadienoic Acid, via Glucuronidation. LC/MS/MS Characterization of the GSH−Glucuronide Diconjugates
inferredcites →https://doi.org/10.1124/dmd.105.004861openalex-snapshot
PATHWAYS OF CARBAMAZEPINE BIOACTIVATION IN VITRO: II. THE ROLE OF HUMAN CYTOCHROME P450 ENZYMES IN THE FORMATION OF 2-HYDROXYIMINOSTILBENE
inferredcites →https://doi.org/10.1124/dmd.30.11.1170openalex-snapshot
Pathways of Carbamazepine Bioactivation in Vitro I. Characterization of Human Cytochromes P450 Responsible for the Formation of 2- and 3-Hydroxylated Metabolites
inferredcites →https://doi.org/10.2174/138920006777697972openalex-snapshot
Utility of the Hybrid LTQ-FTMS for Drug Metabolism Applications

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inferred← citeshttps://doi.org/10.2139/ssrn.4796224openalex-extracted
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inferred← citeshttps://doi.org/10.1002/9780470409817.ch4openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9780470890387.ch7openalex-snapshot
Strategies for the Detection of Reactive Intermediates in Drug Discovery and Development
inferred← citeshttps://doi.org/10.1002/9780470921920.edm054openalex-snapshot
Drug Metabolism in Drug Safety Evaluation
inferred← citeshttps://doi.org/10.1002/9780470921920.edm090openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9780470921920.edm097openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9780470929278.ch13openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/9781118180730.ch6openalex-snapshot
LC‐MS in Drug Metabolism and Pharmacokinetics: A Pharmaceutical Industry Perspective
inferred← citeshttps://doi.org/10.1002/9781118180778.ch20openalex-snapshot
Application of Accurate Mass Spectrometry for Metabolite Identification
inferred← citeshttps://doi.org/10.1002/9781118516157.ch12openalex-snapshot
Screening Reactive Metabolites: Role of Liquid Chromatography–High‐Resolution Mass Spectrometry in Combination with “Intelligent” Data Mining Tools
inferred← citeshttps://doi.org/10.1002/9781118541203.xen0025openalex-snapshot
Drug Metabolite Identification with High‐resolution Mass Spectrometry
inferred← citeshttps://doi.org/10.1002/9781119171003.ch7openalex-snapshot
Liquid Chromatography‐Mass Spectrometry (LC‐MS) Quantification of Reactive Metabolites
inferred← citeshttps://doi.org/10.1002/9781119294269.ch5openalex-snapshot
Identification Strategies
inferred← citeshttps://doi.org/10.1002/9783527673391.ch1openalex-snapshot
Introduction to Mass Spectrometry, a Tutorial
inferred← citeshttps://doi.org/10.1002/bdd.659openalex-snapshot
Integrated strategies for assessment of metabolite exposure in humans during drug development: analytical challenges and clinical development considerations
inferred← citeshttps://doi.org/10.1002/bmc.1136openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/etc.5182openalex-snapshot
Environmental Sources, Chemistry, Fate, and Transport of Per- and Polyfluoroalkyl Substances: State of the Science, Key Knowledge Gaps, and Recommendations Presented at the August 2019 SETAC Focus Topic Meeting
inferred← citeshttps://doi.org/10.1002/jms.1302openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jms.1311openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/jms.1390openalex-snapshot
An algorithm for thorough background subtraction from high‐resolution LC/MS data: application for detection of glutathione‐trapped reactive metabolites
inferred← citeshttps://doi.org/10.1002/jms.1475openalex-snapshot
Screening and characterization of reactive metabolites using glutathione ethyl ester in combination with Q‐trap mass spectrometry
inferred← citeshttps://doi.org/10.1002/jms.1610openalex-snapshot
Mass defect filter technique and its applications to drug metabolite identification by high‐resolution mass spectrometry
inferred← citeshttps://doi.org/10.1002/jms.1921openalex-snapshot
It is time for a paradigm shift in drug discovery bioanalysis: from SRM to HRMS
inferred← citeshttps://doi.org/10.1002/jms.2005openalex-snapshot
High‐resolution mass spectrometry method for the detection, characterization and quantitation of pharmaceuticals in water
inferred← citeshttps://doi.org/10.1002/jms.2953openalex-snapshot
The use of mass defect in modern mass spectrometry
inferred← citeshttps://doi.org/10.1002/jms.4320openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/mas.20186openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/pca.2508openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3504openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3585openalex-snapshot
Mass defect profiles of biological matrices and the general applicability of mass defect filtering for metabolite detection
inferred← citeshttps://doi.org/10.1002/rcm.3758openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3854openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3881openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3951openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.3953openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.4041openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.4045openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.4207openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.4399openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.4507openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.5005openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.5197openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.6135openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.7062openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/rcm.8679openalex-snapshot
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inferred← citeshttps://doi.org/10.1002/sscp.70213openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/978-1-4939-7677-5_13openalex-snapshot
Reactive Metabolite Assessment in Drug Discovery and Development in Support of Safe Drug Design
inferred← citeshttps://doi.org/10.1007/978-3-642-00663-0_19openalex-snapshot
Approaches for Minimizing Metabolic Activation of New Drug Candidates in Drug Discovery
inferred← citeshttps://doi.org/10.1007/978-981-33-6064-8_20openalex-snapshot
The Application of Mass Spectrometry in Drug Metabolism and Pharmacokinetics
inferred← citeshttps://doi.org/10.1007/s00216-019-02239-6openalex-snapshot
In vitro metabolism of triclosan studied by liquid chromatography–high-resolution tandem mass spectrometry
inferred← citeshttps://doi.org/10.1007/s00216-024-05608-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s11356-014-3187-yopenalex-snapshot
Post-acquisition data processing for the screening of transformation products of different organic contaminants. Two-year monitoring of river water using LC-ESI-QTOF-MS and GCxGC-EI-TOF-MS
inferred← citeshttps://doi.org/10.1007/s11418-024-01835-wopenalex-snapshot
Screening and identification of reactive metabolic compounds of Cortex Periplocae based on glutathione capture-mass spectrometry
inferred← citeshttps://doi.org/10.1007/s11419-016-0312-2openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s12127-012-0113-1openalex-snapshot
Resolving the microcosmos of complex samples: UPLC/travelling wave ion mobility separation high resolution mass spectrometry for the analysis of in vivo drug metabolism studies
inferred← citeshttps://doi.org/10.1007/s13361-012-0351-9openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s13361-012-0354-6openalex-snapshot
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inferred← citeshttps://doi.org/10.1007/s40495-016-0079-5openalex-snapshot
The Opportunities of Metabolomics in Drug Safety Evaluation
inferred← citeshttps://doi.org/10.1007/s40495-018-0144-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-12-820018-6.00003-xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-323-90560-2.00010-8openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/b978-0-323-95488-4.00161-3openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.aca.2012.04.024openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.aca.2013.01.012openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.aca.2013.06.022openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.aca.2015.09.034openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.aca.2017.08.047openalex-snapshot
The application of a novel high-resolution mass spectrometry-based analytical strategy to rapid metabolite profiling of a dual drug combination in humans
inferred← citeshttps://doi.org/10.1016/j.cbi.2008.09.014openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.cbi.2009.06.017openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chroma.2010.02.022openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chroma.2016.03.068openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chroma.2020.461160openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chroma.2021.462029openalex-snapshot
An enhanced strategy integrating offline superimposed two-dimensional separation with mass defect filter and diagnostic ion filter: Comprehensive characterization of steroid alkaloids in Fritillariae Pallidiflorae Bulbus as a case study
inferred← citeshttps://doi.org/10.1016/j.chroma.2021.462095openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.chroma.2026.467531openalex-snapshot
Mass spectrometry‑based chemoproteomics for modern drug screening: A critical review and the 3M framework (Match–Map–Mine)
inferred← citeshttps://doi.org/10.1016/j.drudis.2008.11.002openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.jasms.2009.07.018openalex-snapshot
Nucleophile addition of reduced glutathione on 2-methyl-2-nitroso compound: A combined electron paramagnetic resonance spectroscopy and electrospray tandem mass spectrometry study
inferred← citeshttps://doi.org/10.1016/j.jchromb.2011.08.025openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.microc.2024.112287openalex-snapshot
Strategy of mass defect filter combined with characteristic fragment analysis for the chemical profiling of Dictamnus dasycarpus Turcz. From multiple regions
inferred← citeshttps://doi.org/10.1016/j.talanta.2013.11.025openalex-snapshot
Rapid screening and identification of target constituents using full scan-parent ions list-dynamic exclusion acquisition coupled to diagnostic product ions analysis on a hybrid LTQ-Orbitrap mass spectrometer
inferred← citeshttps://doi.org/10.1016/j.tiv.2010.11.002openalex-snapshot
d-Isomer of gly-tyr-pro-cys-pro-his-pro peptide: A novel and sensitive in vitro trapping agent to detect reactive metabolites by electrospray mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.toxrep.2015.07.002openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.trac.2010.10.014openalex-snapshot
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inferred← citeshttps://doi.org/10.1016/j.vascn.2015.08.157openalex-snapshot
Characterization of a highly sensitive and selective novel trapping reagent, stable isotope labeled glutathione ethyl ester, for the detection of reactive metabolites
inferred← citeshttps://doi.org/10.1016/s1872-0854(09)00003-4openalex-snapshot
Chapter 3 Applications of Quadrupole-Linear Ion Trap Mass Spectrometry to the Analysis of Reactive Metabolites in Drug Discovery and Development
inferred← citeshttps://doi.org/10.1021/ac202280fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/ac504737xopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/ac800887hopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/ac900778yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.analchem.3c01094openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.chemrestox.3c00162openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.chemrestox.3c00209openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.chemrestox.6b00385openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jcim.0c00360openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jcim.9b00836openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acs.jmedchem.2c00336openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/acsomega.5c03129openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/bc900289mopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx1000046openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx100131fopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx1003694openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx200033vopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx300339uopenalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx8001115openalex-snapshot
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inferred← citeshttps://doi.org/10.1021/tx900035jopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/b921638copenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c5ra13276bopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c7nj04958gopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/c9ra10871hopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/d4ay00577eopenalex-snapshot
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inferred← citeshttps://doi.org/10.1074/jbc.r110.200055openalex-snapshot
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inferred← citeshttps://doi.org/10.1074/mcp.m111.009431openalex-snapshot
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inferred← citeshttps://doi.org/10.1080/00498254.2018.1504256openalex-snapshot
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inferred← citeshttps://doi.org/10.1080/19440049.2011.618467openalex-snapshot
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inferred← citeshttps://doi.org/10.1093/chromsci/bmu056openalex-snapshot
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inferred← citeshttps://doi.org/10.1124/dmd.109.027300openalex-snapshot
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inferred← citeshttps://doi.org/10.1124/dmd.124.001661openalex-snapshot
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inferred← citeshttps://doi.org/10.1177/1087057113492852openalex-snapshot
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inferred← citeshttps://doi.org/10.1201/9781420092219-c5openalex-snapshot
Metabolite Identification Strategies and Procedures
inferred← citeshttps://doi.org/10.1201/9781420092219-c6openalex-snapshot
Reactive Metabolite Screening and Covalent-Binding Assays
inferred← citeshttps://doi.org/10.1517/17425250802665706openalex-snapshot
Analytical strategies for the screening and evaluation of chemically reactive drug metabolites
inferred← citeshttps://doi.org/10.1517/17425255.2015.1048222openalex-snapshot
Detecting reactive drug metabolites for reducing the potential for drug toxicity
inferred← citeshttps://doi.org/10.15760/etd.3078openalex-snapshot
Biomimetic Tools in Oxidative Metabolism: Characterization of Reactive Metabolites from Antithyroid Drugs
inferred← citeshttps://doi.org/10.2174/138920011795202974openalex-snapshot
Conventional and Novel Approaches in Generating and Characterization of Reactive Intermediates from Drugs/Drug Candidates
inferred← citeshttps://doi.org/10.25148/etd.fidc007036openalex-snapshot
An Investigation into the Adduct Forming Potential of Drugs of Abuse with Peptides and Proteins
inferred← citeshttps://doi.org/10.3109/00498254.2012.696740openalex-snapshot
Glutathione conjugation of busulfan produces a hydroxyl radical-trapping dehydroalanine metabolite
inferred← citeshttps://doi.org/10.3109/03602532.2014.1001029openalex-snapshot
Applications of mass spectrometry in drug metabolism: 50 years of progress
inferred← citeshttps://doi.org/10.3390/mi12091099openalex-snapshot
The Fabrication of Amino Acid Incorporated Nanoflowers with Intrinsic Peroxidase-like Activity and Its Application for Efficiently Determining Glutathione with TMB Radical Cation as Indicator
inferred← citeshttps://doi.org/10.3390/molecules27113638openalex-snapshot
Mass Defect Filtering-Oriented Identification of Resin Glycosides from Root of Convolvulus scammonia Based on Quadrupole-Orbitrap Mass Spectrometer
inferred← citeshttps://doi.org/10.33915/etd.2940openalex-snapshot
Properties of a dehydroalanine analog of glutathione: A reactive electrophilic busulfan metabolite
inferred← citeshttps://doi.org/10.4155/bio.09.32openalex-snapshot
From Known Knowns to Known Unknowns: Predictingin VivoDrug Metabolites
inferred← citeshttps://doi.org/10.4155/bio.09.65openalex-snapshot
Advances in Bioanalytical LC–MS Using the Orbitrap™ Mass Analyzer
inferred← citeshttps://doi.org/10.4155/bio.10.83openalex-snapshot
Novel MS Solutions Inspired by MIST
inferred← citeshttps://doi.org/10.4155/bio.12.43openalex-snapshot
Recent Advances in Metabolite Identification And Quantitative Bioanalysis By Lc–Q-Tof Ms
inferred← citeshttps://doi.org/10.4155/bio.12.5openalex-snapshot
Application of Lc–High-Resolution Ms With ‘Intelligent’ Data Mining Tools For Screening Reactive Drug Metabolites
inferred← citeshttps://doi.org/10.4155/bio.13.100openalex-snapshot
Applications of High-Resolution MS in Bioanalysis
inferred← citeshttps://doi.org/10.4155/bio.13.3openalex-snapshot
Metabolite Structure Analysis by High-Resolution MS: Supporting Drug-Development Studies
inferred← citeshttps://doi.org/10.5772/intechopen.1001481openalex-snapshot
Non-radiolabeled Study to Evaluate the Metabolism and Residue Kinetics of Veterinary Drugs in Food-producing Animals and Anti-doping Analysis in Equine Sports: Application of High-Resolution Mass Spectrometry
inferred← citeshttps://doi.org/10.5772/intechopen.1001524openalex-snapshot
Equine Science - Applications and Implications of New Technologies [Working Title]
Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.