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An Edaravone-Guided Design of a Rhodamine-Based Turn-on Fluorescent Probe for Detecting Hydroxyl Radicals in Living Systems

https://doi.org/10.1021/acs.analchem.1c03877
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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HKOH‐1: A Highly Sensitive and Selective Fluorescent Probe for Detecting Endogenous Hydroxyl Radicals in Living Cells
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Rationally Designed Fluorescence .OH Probe with High Sensitivity and Selectivity for Monitoring the Generation of .OH in Iron Autoxidation without Addition of H2O2
inferredcites →https://doi.org/10.1002/anie.201901318openalex-snapshot
Illuminating the Function of the Hydroxyl Radical in the Brains of Mice with Depression Phenotypes by Two‐Photon Fluorescence Imaging
inferredcites →https://doi.org/10.1002/anie.201916357openalex-snapshot
Quantitative Design of Bright Fluorophores and AIEgens by the Accurate Prediction of Twisted Intramolecular Charge Transfer (TICT)
inferredcites →https://doi.org/10.1002/anie.202102377openalex-snapshot
High‐Contrast Fluorescence Diagnosis of Cancer Cells/Tissues Based on β‐Lapachone‐Triggered ROS Amplification Specific in Cancer Cells
inferredcites →https://doi.org/10.1002/anie.202107877openalex-snapshot
Hemicyanine‐Based Near‐Infrared Activatable Probes for Imaging and Diagnosis of Diseases
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Molecular Origins of Heteroatom Engineering on the Emission Wavelength Tuning, Quantum Yield Variations and Fluorogenicity of NBD‐like SCOTfluors
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On the •OH and •OOH scavenging activity of 3‐methyl‐1‐pyridin‐2‐yl‐5‐pyrazolone: Comparisons with its parent compound, edaravone
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Hydroxyl Radical Generation During Mitochondrial Electron-Transfer and the Formation of 8-Hydroxydesoxyguanosine in Mitochondrial-DNA
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Reinterpretation of the anomalous fluorescense of -n,n-dimethylamino-benzonitrile
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Free radicals in biology and medicine
inferredcites →https://doi.org/10.1016/j.biomaterials.2017.10.043openalex-snapshot
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inferredcites →https://doi.org/10.1016/j.bmc.2020.115463openalex-snapshot
Chemical reactivity and uses of 1-phenyl-3-methyl-5-pyrazolone (PMP), also known as edaravone
inferredcites →https://doi.org/10.1016/j.ccr.2020.213457openalex-snapshot
Fluorescent detectors for hydroxyl radical and their applications in bioimaging: A review
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DT-diaphorase: a target for new anticancer drugs
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A comprehensive review on β-lapachone: Mechanisms, structural modifications, and therapeutic potentials
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inferredcites →https://doi.org/10.1016/j.freeradbiomed.2015.03.033openalex-snapshot
Role of labile iron in the toxicity of pharmacological ascorbate
inferredcites →https://doi.org/10.1016/j.jss.2018.03.020openalex-snapshot
Dose-dependency of multiple free radical-scavenging activity of edaravone
inferredcites →https://doi.org/10.1016/s0045-6535(99)00296-9openalex-snapshot
Quantitation of hydroxyl radical during Fenton oxidation following a single addition of iron and peroxide
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Cinnamaldehyde induces apoptosis by ROS-mediated mitochondrial permeability transition in human promyelocytic leukemia HL-60 cells
inferredcites →https://doi.org/10.1016/s1056-8719(98)00025-2openalex-snapshot
Ferrous iron-induced luminol chemiluminescence: a method for hydroxyl radical study
inferredcites →https://doi.org/10.1021/acs.analchem.9b04002openalex-snapshot
Lighting Up NIR-II Fluorescence in Vivo: An Activable Probe for Noninvasive Hydroxyl Radical Imaging
inferredcites →https://doi.org/10.1021/acs.jmedchem.8b01424openalex-snapshot
Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer
inferredcites →https://doi.org/10.1021/bi0600087openalex-snapshot
The Crystal Structure of NAD(P)H Quinone Oxidoreductase 1 in Complex with Its Potent Inhibitor Dicoumarol
inferredcites →https://doi.org/10.1021/cb600132mopenalex-snapshot
Fluorogenic Label for Biomolecular Imaging
inferredcites →https://doi.org/10.1021/cr940745lopenalex-snapshot
Structural Changes Accompanying Intramolecular Electron Transfer: Focus on Twisted Intramolecular Charge-Transfer States and Structures
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The mechanism of iron EDTA catalyzed superoxide dismutation
inferredcites →https://doi.org/10.1021/jacs.5b12848openalex-snapshot
Real-Time Discrimination and Versatile Profiling of Spontaneous Reactive Oxygen Species in Living Organisms with a Single Fluorescent Probe
inferredcites →https://doi.org/10.1021/jacs.9b04893openalex-snapshot
Quaternary Piperazine-Substituted Rhodamines with Enhanced Brightness for Super-Resolution Imaging
inferredcites →https://doi.org/10.1021/jacs.9b09722openalex-snapshot
Ferroptosis Accompanied by •OH Generation and Cytoplasmic Viscosity Increase Revealed via Dual-Functional Fluorescence Probe
inferredcites →https://doi.org/10.1021/jo010067kopenalex-snapshot
Mechanisms of Acid-Catalyzed Z/E Isomerization of Imines
inferredcites →https://doi.org/10.1021/jp110400topenalex-snapshot
OH Radical Scavenging Activity of Edaravone: Mechanism and Kinetics
inferredcites →https://doi.org/10.1021/jp963267mopenalex-snapshot
Density Functional Study of the Radical Reactions of 3-Methyl-1-phenyl-2-pyrazolin-5-one (MCI-186): Implication for the Biological Function of MCI-186 as a Highly Potent Antioxidative Radical Scavenger
inferredcites →https://doi.org/10.1021/ol102182jopenalex-snapshot
HKGreen-3: A Rhodol-Based Fluorescent Probe for Peroxynitrite
inferredcites →https://doi.org/10.1021/ol701620hopenalex-snapshot
A Water-Soluble “Switching On” Fluorescent Chemosensor of Selectivity to Cd2+
inferredcites →https://doi.org/10.1038/35030140openalex-snapshot
Superoxide dismutase as a target for the selective killing of cancer cells
inferredcites →https://doi.org/10.1038/nmeth.3256openalex-snapshot
A general method to improve fluorophores for live-cell and single-molecule microscopy
inferredcites →https://doi.org/10.1038/nrd4002openalex-snapshot
Modulation of oxidative stress as an anticancer strategy
inferredcites →https://doi.org/10.1039/b100085nopenalex-snapshot
Fe(ii)–EDTA chelate-induced aromatic hydroxylation of terephthalate as a new method for the evaluation of hydroxyl radical-scavenging ability
inferredcites →https://doi.org/10.1039/d0cc00233jopenalex-snapshot
An endoplasmic reticulum-targeting fluorescent probe for imaging ˙OH in living cells
inferredcites →https://doi.org/10.1039/d0ob02456bopenalex-snapshot
Asymmetric bismuth-rhodamines as an activatable fluorogenic photosensitizer
inferredcites →https://doi.org/10.1042/bj3130017openalex-snapshot
Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer
inferredcites →https://doi.org/10.1073/pnas.0704030104openalex-snapshot
Molecular mechanism for metal-independent production of hydroxyl radicals by hydrogen peroxide and halogenated quinones
inferredcites →https://doi.org/10.1073/pnas.95.17.9738openalex-snapshot
DNA strand breaking by the hydroxyl radical is governed by the accessible surface areas of the hydrogen atoms of the DNA backbone
inferredcites →https://doi.org/10.1074/jbc.275.8.5416openalex-snapshot
NAD(P)H:Quinone Oxidoreductase Activity Is the Principal Determinant of β-Lapachone Cytotoxicity
inferredcites →https://doi.org/10.1080/13510002.1996.11747069openalex-snapshot
Antioxidant activity of 3-methyl-1-phenyl-2-pyrazolin-5-one
inferredcites →https://doi.org/10.1080/21678421.2017.1353101openalex-snapshot
Edaravone and its clinical development for amyotrophic lateral sclerosis
inferredcites →https://doi.org/10.1096/fj.02-0130fjeopenalex-snapshot
High glucose‐induced oxidative stress causes apoptosis in proximal tubular epithelial cells and is mediated by multiple caspases
inferredcites →https://doi.org/10.1111/j.1527-3466.2008.00041.xopenalex-snapshot
The Novel Antioxidant Edaravone: From Bench to Bedside
inferredcites →https://doi.org/10.1124/jpet.108.148676openalex-snapshot
Edaravone, a Free Radical Scavenger, Protects against Retinal Damage in Vitro and in Vivo
inferredcites →https://doi.org/10.1248/cpb.52.186openalex-snapshot
The Reaction Rate of Edaravone (3-Methyl-1-phenyl-2-pyrazolin-5-one (MCI-186)) with Hydroxyl Radical

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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