On the public citation graph

Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Causes Abnormal Locomotion Behaviors and Neurodegeneration in Caenorhabditis elegans

https://doi.org/10.1021/acs.est.2c08644

0 signed · 213 inferred · view as graph

Inferred edges come from two machine sources: sweeps of open repository metadata (mostly SSRN and Zenodo), and a bulk OpenAlex citation snapshot. Every row below is labelled with the one it came from. Neither is a complete citation index — absence here is not evidence of absence.

Is this your work? Sign in with ORCID and put your name on the claims that are yours.

Claim with ORCID

Reference health. See whether every reference in this work resolves to a known work and none has been retracted — and get a dated CiteStamped badge you can embed.

See reference health

What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/etc.3937openalex-snapshot

Mixture effects of copper, cadmium, and zinc on mortality and behavior ofCaenorhabditis elegans

inferredcites →https://doi.org/10.1002/jat.4360openalex-snapshot

A review of transgenerational and multigenerational toxicology in the in vivo model animal Caenorhabditis elegans

inferredcites →https://doi.org/10.1002/neu.10245openalex-snapshot

Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans

inferredcites →https://doi.org/10.1007/978-981-13-3633-1openalex-snapshot

Molecular Toxicology in Caenorhabditis elegans

inferredcites →https://doi.org/10.1007/978-981-15-6129-0openalex-snapshot

Exposure Toxicology in Caenorhabditis elegans

inferredcites →https://doi.org/10.1007/978-981-16-6746-6openalex-snapshot

Toxicology at Environmentally Relevant Concentrations in Caenorhabditis elegans

inferredcites →https://doi.org/10.1007/s12640-020-00175-3openalex-snapshot

Nickel-Induced Developmental Neurotoxicity in C. elegans Includes Cholinergic, Dopaminergic and GABAergic Degeneration, Altered Behaviour, and Increased SKN-1 Activity

inferredcites →https://doi.org/10.1016/0896-6273(95)90231-7openalex-snapshot

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

inferredcites →https://doi.org/10.1016/j.atmosenv.2006.09.041openalex-snapshot

Emissions of polycyclic aromatic hydrocarbons (PAHs) from the pyrolysis of scrap tires

inferredcites →https://doi.org/10.1016/j.biocel.2004.02.030openalex-snapshot

Calreticulin, a Ca2+-binding chaperone of the endoplasmic reticulum

inferredcites →https://doi.org/10.1016/j.chemosphere.2019.02.143openalex-snapshot

Study on transformation and degradation of bisphenol A by Trametes versicolor laccase and simulation of molecular docking

inferredcites →https://doi.org/10.1016/j.chemosphere.2019.125730openalex-snapshot

Toxicity assessment of parabens in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.chemosphere.2022.134687openalex-snapshot

Multi-walled carbon nanotubes induce transgenerational toxicity associated with activation of germline long non-coding RNA linc-7 in C. elegans

inferredcites →https://doi.org/10.1016/j.chemosphere.2022.136154openalex-snapshot

Polystyrene nanoparticles cause dynamic alteration in mitochondrial unfolded protein response from parents to the offspring in C. elegans

inferredcites →https://doi.org/10.1016/j.chemosphere.2023.137986openalex-snapshot

Exposure to multi-walled carbon nanotubes causes suppression in octopamine signal associated with transgenerational toxicity induction in C. elegans

inferredcites →https://doi.org/10.1016/j.ecoenv.2019.01.101openalex-snapshot

Understanding the interaction of single-walled carbon nanotube (SWCNT) on estrogen receptor: A combined molecular dynamics and experimental study

inferredcites →https://doi.org/10.1016/j.ecoenv.2021.112018openalex-snapshot

Dysregulated mir-76 mediated a protective response to nanopolystyrene by modulating heme homeostasis related molecular signaling in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.ecoenv.2021.112239openalex-snapshot

Response of tyramine and glutamate related signals to nanoplastic exposure in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.ecoenv.2021.112732openalex-snapshot

Neuronal Gα subunits required for the control of response to polystyrene nanoparticles in the range of μg/L in C. elegans

inferredcites →https://doi.org/10.1016/j.ecoenv.2022.114022openalex-snapshot

Induction of transgenerational toxicity is associated with the activated germline insulin signals in nematodes exposed to nanoplastic at predicted environmental concentrations

inferredcites →https://doi.org/10.1016/j.envint.2019.05.048openalex-snapshot

Ecological toxicity reduction of dinotefuran to honeybee: New perspective from an enantiomeric level

inferredcites →https://doi.org/10.1016/j.envint.2021.106405openalex-snapshot

Polycyclic aromatic hydrocarbon exposure, oxidative potential in dust, and their relationships to oxidative stress in human body: A case study in the indoor environment of Guangzhou, South China

inferredcites →https://doi.org/10.1016/j.envpol.2019.113406openalex-snapshot

Airborne toluene exposure causes germline apoptosis and neuronal damage that promotes neurobehavioural changes in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.envpol.2020.116036openalex-snapshot

Long-term toxicity of lindane through oxidative stress and cell apoptosis in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.envpol.2021.117659openalex-snapshot

Detection of selected tire wear compounds in urban receiving waters

inferredcites →https://doi.org/10.1016/j.envpol.2022.119927openalex-snapshot

Review of the toxicity and potential molecular mechanisms of parental or successive exposure to environmental pollutants in the model organism Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.envpol.2022.120029openalex-snapshot

Assessing the hepatotoxicity of PFOA, PFOS, and 6:2 Cl-PFESA in black-spotted frogs (Rana nigromaculata) and elucidating potential association with gut microbiota

inferredcites →https://doi.org/10.1016/j.etap.2008.11.011openalex-snapshot

The neurotoxic effects of heavy metal exposure on GABAergic nervous system in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.ijpddr.2016.09.001openalex-snapshot

In silico analysis of the binding of anthelmintics to Caenorhabditis elegans P-glycoprotein 1

inferredcites →https://doi.org/10.1016/j.impact.2020.100256openalex-snapshot

Dysregulated mir-354 enhanced the protective response to nanopolystyrene by affecting the activity of TGF-β signaling pathway in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.impact.2022.100403openalex-snapshot

Long-term exposure to polystyrene nanoparticles causes transgenerational toxicity by affecting the function and expression of MEV-1 and DAF-2 signals in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.impact.2022.100425openalex-snapshot

Alteration in Wnt signaling mediates induction of transgenerational toxicity of polystyrene nanoplastics in C. elegans

inferredcites →https://doi.org/10.1016/j.jhazmat.2022.129302openalex-snapshot

Nanoplastics cause transgenerational toxicity through inhibiting germline microRNA mir-38 in C. elegans

inferredcites →https://doi.org/10.1016/j.pestbp.2017.03.005openalex-snapshot

Deltamethrin affects the expression of voltage-gated calcium channel α1 subunits and the locomotion, egg-laying, foraging behavior of Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.scitotenv.2018.05.314openalex-snapshot

Chronic exposure to triadimenol at environmentally relevant concentration adversely affects aging biomarkers in Caenorhabditis elegans associated with insulin/IGF-1 signaling pathway

inferredcites →https://doi.org/10.1016/j.scitotenv.2019.134817openalex-snapshot

Toxicity comparison between pristine and sulfonate modified nanopolystyrene particles in affecting locomotion behavior, sensory perception, and neuronal development in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.scitotenv.2020.138378openalex-snapshot

Neuronal ERK MAPK signaling in response to low-dose nanopolystyrene exposure by suppressing insulin peptide expression in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.scitotenv.2020.141047openalex-snapshot

Response of DBL-1/TGF-β signaling-mediated neuron-intestine communication to nanopolystyrene in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.scitotenv.2022.156013openalex-snapshot

Multiview behavior and neurotransmitter analysis of zebrafish dyskinesia induced by 6PPD and its metabolites

inferredcites →https://doi.org/10.1016/j.scitotenv.2022.158468openalex-snapshot

Tyre Additive Chemicals, Tyre Road Wear Particles and High Production Polymers in Surface Water at 5 Urban Centres in Queensland, Australia

inferredcites →https://doi.org/10.1016/j.scitotenv.2022.160591openalex-snapshot

Long-term exposure to tire-derived 6-PPD quinone causes intestinal toxicity by affecting functional state of intestinal barrier in Caenorhabditis elegans

inferredcites →https://doi.org/10.1016/j.taap.2018.03.016openalex-snapshot

C. elegans as a model in developmental neurotoxicology

inferredcites →https://doi.org/10.1016/j.watres.2018.03.051openalex-snapshot

Tire wear particles in the aquatic environment - A review on generation, analysis, occurrence, fate and effects

inferredcites →https://doi.org/10.1016/j.watres.2022.118122openalex-snapshot

Abiotic oxidative transformation of 6-PPD and 6-PPD quinone from tires and occurrence of their products in snow from urban roads and in municipal wastewater

inferredcites →https://doi.org/10.1016/s0166-2236(00)01548-4openalex-snapshot

Calcium signaling in the ER: its role in neuronal plasticity and neurodegenerative disorders

inferredcites →https://doi.org/10.1016/s0896-6273(01)00432-9openalex-snapshot

Necrotic Cell Death in C. elegans Requires the Function of Calreticulin and Regulators of Ca2+ Release from the Endoplasmic Reticulum

inferredcites →https://doi.org/10.1016/s1001-0742(10)60436-6openalex-snapshot

Behavior toxicity to Caenorhabditis elegans transferred to the progeny after exposure to sulfamethoxazole at environmentally relevant concentrations

inferredcites →https://doi.org/10.1021/acs.est.0c04114openalex-snapshot

Broad Exposure of the North American Environment to Phenolic and Amino Antioxidants and to Ultraviolet Filters

inferredcites →https://doi.org/10.1021/acs.est.1c02723openalex-snapshot

Organic Markers of Tire and Road Wear Particles in Sediments and Soils: Transformation Products of Major Antiozonants as Promising Candidates

inferredcites →https://doi.org/10.1021/acs.est.1c07376openalex-snapshot

New Evidence of Rubber-Derived Quinones in Water, Air, and Soil

inferredcites →https://doi.org/10.1021/acs.est.1c07451openalex-snapshot

Concentrations of Tire Additive Chemicals and Tire Road Wear Particles in an Australian Urban Tributary

inferredcites →https://doi.org/10.1021/acs.est.2c04765openalex-snapshot

Novel Insight into the Mechanisms of Neurotoxicity Induced by 6:6 PFPiA through Disturbing the Gut–Brain Axis

inferredcites →https://doi.org/10.1021/acs.estlett.1c00148openalex-snapshot

Occurrence of Substituted p -Phenylenediamine Antioxidants in Dusts

inferredcites →https://doi.org/10.1021/acs.estlett.1c00682openalex-snapshot

Occurrences of Tire Rubber-Derived Contaminants in Cold-Climate Urban Runoff

inferredcites →https://doi.org/10.1021/acs.estlett.1c00794openalex-snapshot

A Direct Mass Spectrometry Method for the Rapid Analysis of Ubiquitous Tire-Derived Toxin N -(1,3-Dimethylbutyl)- N ′-phenyl- p -phenylenediamine Quinone (6-PPDQ)

inferredcites →https://doi.org/10.1021/acs.estlett.1c00910openalex-snapshot

6PPD-Quinone: Revised Toxicity Assessment and Quantification with a Commercial Standard

inferredcites →https://doi.org/10.1021/acs.estlett.2c00050openalex-snapshot

Acute Toxicity of the Tire Rubber-Derived Chemical 6PPD-quinone to Four Fishes of Commercial, Cultural, and Ecological Importance

inferredcites →https://doi.org/10.1021/acs.estlett.2c00431openalex-snapshot

Exposure to the Tire Rubber-Derived Contaminant 6PPD-Quinone Causes Mitochondrial Dysfunction In Vitro

inferredcites →https://doi.org/10.1021/es204257dopenalex-snapshot

Automobile Tires—A Potential Source of Highly Carcinogenic Dibenzopyrenes to the Environment

inferredcites →https://doi.org/10.1021/es3024379openalex-snapshot

Zinc Leaching from Tire Crumb Rubber

inferredcites →https://doi.org/10.1021/jm970377oopenalex-snapshot

Neuronal Nicotinic Acetylcholine Receptors as Targets for Drug Discovery

inferredcites →https://doi.org/10.1021/tx800074eopenalex-snapshot

Arsenite-Induced Germline Apoptosis through a MAPK-Dependent, p53-independent Pathway in Caenorhabditis elegans

inferredcites →https://doi.org/10.1038/364337a0openalex-snapshot

The GABAergic nervous system of Caenorhabditis elegans

inferredcites →https://doi.org/10.1038/372780a0openalex-snapshot

Control of type-D GABAergic neuron differentiation by C. elegans UNC-30 homeodomain protein

inferredcites →https://doi.org/10.1038/nature01108openalex-snapshot

Specific aspartyl and calpain proteases are required for neurodegeneration in C. elegans

inferredcites →https://doi.org/10.1038/nprot.2016.051openalex-snapshot

Computational protein–ligand docking and virtual drug screening with the AutoDock suite

inferredcites →https://doi.org/10.1038/nrg1018openalex-snapshot

Dying for a cause: invertebrate genetics takes on human neurodegeneration

inferredcites →https://doi.org/10.1038/nrn731openalex-snapshot

Emerging structure of the Nicotinic Acetylcholine receptors

inferredcites →https://doi.org/10.1039/c9en00473dopenalex-snapshot

Neuronal damage induced by nanopolystyrene particles in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1039/d1en00835hopenalex-snapshot

Increase in germline methyltransferases governing the methylation of histone H3K9 is associated with transgenerational nanoplastic toxicity in Caenorhabditis elegans

inferredcites →https://doi.org/10.1080/10408444.2019.1626801openalex-snapshot

Caenorhabditis elegansas a tool for environmental risk assessment: emerging and promising applications for a “nobelized worm”

inferredcites →https://doi.org/10.1080/10937404.2014.933722openalex-snapshot

Toxicity Testing of Neurotoxic Pesticides inCaenorhabditis elegans

inferredcites →https://doi.org/10.1083/jcb.134.4.885openalex-snapshot

unc-68 encodes a ryanodine receptor involved in regulating C. elegans body-wall muscle contraction.

inferredcites →https://doi.org/10.1093/genetics/77.1.71openalex-snapshot

THE GENETICS OF CAENORHABDITIS ELEGANS

inferredcites →https://doi.org/10.1093/toxsci/kfn121openalex-snapshot

Caenorhabditis elegans: An Emerging Model in Biomedical and Environmental Toxicology

inferredcites →https://doi.org/10.1098/rstb.1986.0056openalex-snapshot

The structure of the nervous system of the nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1111/j.1474-9726.2007.00275.xopenalex-snapshot

Calcium and neurodegeneration

inferredcites →https://doi.org/10.1126/science.282.5396.2028openalex-snapshot

Neurobiology of the Caenorhabditis elegans Genome

inferredcites →https://doi.org/10.1126/science.abd6951openalex-snapshot

A ubiquitous tire rubber–derived chemical induces acute mortality in coho salmon

inferredcites →https://doi.org/10.1186/s12302-020-00331-8openalex-snapshot

Exposure to low-dose nanopolystyrene induces the response of neuronal JNK MAPK signaling pathway in nematode Caenorhabditis elegans

inferredcites →https://doi.org/10.1289/ehp.1206198openalex-snapshot

Sulfated Metabolites of Polychlorinated Biphenyls Are High-Affinity Ligands for the Thyroid Hormone Transport Protein Transthyretin

inferredcites →https://doi.org/10.1371/journal.pone.0004690openalex-snapshot

A β-Catenin-Dependent Wnt Pathway Mediates Anteroposterior Axon Guidance in C. elegans Motor Neurons

inferredcites →https://doi.org/10.1371/journal.pone.0074908openalex-snapshot

A Network of HSPG Core Proteins and HS Modifying Enzymes Regulates Netrin-Dependent Guidance of D-Type Motor Neurons in Caenorhabditis elegans

inferredcites →https://doi.org/10.1534/genetics.116.195669openalex-snapshot

Locomotion Behavior Is Affected by the GαS Pathway and the Two-Pore-Domain K+ Channel TWK-7 Interacting in GABAergic Motor Neurons in Caenorhabditis elegans

inferredcites →https://doi.org/10.1897/02-565openalex-snapshot

The effects of metals and food availability on the behavior of Caenorhabditis elegans

inferredcites →https://doi.org/10.1897/03-264openalex-snapshot

Assessing behavioral toxicity with Caenorhabditis elegans

inferredcites →https://doi.org/10.3389/fphar.2022.949608openalex-snapshot

Beneficial effect of Xuebijing against Pseudomonas aeruginosa infection in Caenorhabditis elegans

inferredcites →https://doi.org/10.3390/toxics10110699openalex-snapshot

Nanoplastic Exposure at Predicted Environmental Concentrations Induces Activation of Germline Ephrin Signal Associated with Toxicity Formation in the Caenorhabditis elegans Offspring

inferredcites →https://doi.org/10.5094/apr.2014.089openalex-snapshot

Ozone distributions and urban air quality during summer in Agra – a world heritage site

inferredcites →https://doi.org/10.5487/tr.2012.28.1.019openalex-snapshot

Involvement of Caenohabditis elegans MAPK Signaling Pathways in Oxidative Stress Response Induced by Silver Nanoparticles Exposure

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4688983openalex-extracted

Chronic Exposure to 6-Ppd Quinone at Environmentally Relevant Concentrations Causes Neurotoxicity by Affecting Dopaminergic, Serotonergic, Glutamatergic, and Gabaergic Neuronal Systems in Caenorhabditis Elegans

inferred← citeshttps://doi.org/10.1002/jat.4972openalex-snapshot

Different Toxic Effects of Polystyrene Microplastics and Nanoplastics on Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1007/978-981-92-1389-4_12openalex-snapshot

Regulation of Transgenerational Toxicity by Metabolic Signals

inferred← citeshttps://doi.org/10.1007/978-981-92-1389-4_16openalex-snapshot

Protective Responses Against Transgenerational Toxicity

inferred← citeshttps://doi.org/10.1007/978-981-92-1389-4_3openalex-snapshot

Factors Affecting Transgenerational Toxicity

inferred← citeshttps://doi.org/10.1007/978-981-92-1389-4_4openalex-snapshot

Roles of Transgenerational Translocation and Biological Barrier in Controlling Transgenerational Toxicity of Pollutants

inferred← citeshttps://doi.org/10.1007/978-981-92-5166-7_1openalex-snapshot

Values of Caenorhabditis elegans for Pharmacological Study

inferred← citeshttps://doi.org/10.1007/978-981-92-5166-7_4openalex-snapshot

Physiological and Pathological Models for Pharmacological Study

inferred← citeshttps://doi.org/10.1007/978-981-92-5166-7_7openalex-snapshot

Target Organ Pharmacology

inferred← citeshttps://doi.org/10.1007/s10646-026-03080-1openalex-snapshot

Crawling towards complex interactions: the impact of 6PPD-quinone and increased temperatures on the freshwater snail Ampullaceana balthica

inferred← citeshttps://doi.org/10.1007/s12272-023-01459-wopenalex-snapshot

Paeoniflorin increases the survival of Pseudomonas aeruginosa infected Caenorhabditis elegans at the immunosuppression stage by activating PMK-1, BAR-1, and EGL-1 signals

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2023.139193openalex-snapshot

Polylactic acid microparticles in the range of μg/L reduce reproductive capacity by affecting the gonad development and the germline apoptosis in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.142499openalex-snapshot

Neurotoxicity and accumulation of CPPD quinone at environmentally relevant concentrations in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.142894openalex-snapshot

Combined toxicity of pristine or artificially aged tire wear particles and bisphenols to Tigriopus japonicus

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.142975openalex-snapshot

Exposure to 6-PPD quinone disrupts glucose metabolism associated with lifespan reduction by affecting insulin and AMPK signals in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.chemosphere.2024.143303openalex-snapshot

Treatment with quercetin mitigates polystyrene nanoparticle-induced reduction in neuron capacity by inhibiting dopaminergic neurodegeneration and facilitating dopamine metabolism in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.colsurfa.2026.139762openalex-snapshot

Interfacial mechanisms of 6PPD-quinone adsorption on metal-organic framework functionalized nanocellulose aerogels

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2023.115131openalex-snapshot

Exposure to polystyrene nanoparticles at predicted environmental concentrations enhances toxic effects of Acinetobacter johnsonii AC15 infection on Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116056openalex-snapshot

Polystyrene nanoparticles strengthen high glucose toxicity associated with alteration in insulin signaling pathway in C. elegans

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2024.116689openalex-snapshot

Neurotoxicity from long-term exposure to 6-PPDQ: Recent advances

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2025.117744openalex-snapshot

Tire rubber-derived contaminants 6PPD and 6PPD-quinone reduce attachment and outgrowth of trophoblast spheroids onto endometrial epithelial cells

inferred← citeshttps://doi.org/10.1016/j.ecoenv.2026.119809openalex-snapshot

6PPD-Q exposure promotes hepatocellular carcinoma progression and confers resistance to ferroptosis

inferred← citeshttps://doi.org/10.1016/j.enceco.2025.05.022openalex-snapshot

6-PPD quinone at environmentally relevant concentrations disrupts citric acid cycle in Caenorhabditis elegans: Role of reduction in acetyl CoA and pyruvate contents

inferred← citeshttps://doi.org/10.1016/j.enceco.2025.10.018openalex-snapshot

JNK signal-driven histone methylations mediate transgenerational neurotoxicity of 6-PPD Quinone at predicted environmental concentrations in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.envint.2024.108677openalex-snapshot

Environmental profiles, hazard identification, and toxicological hallmarks of emerging tire rubber-related contaminants 6PPD and 6PPD-quinone

inferred← citeshttps://doi.org/10.1016/j.envpol.2023.121937openalex-snapshot

Exposure to 6-PPD quinone enhances lipid accumulation through activating metabolic sensors of SBP-1 and MDT-15 in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.envpol.2023.122649openalex-snapshot

Disruption of dopamine metabolism by exposure to 6-PPD quinone in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.envpol.2023.122828openalex-snapshot

A mini review on 6PPD quinone: A new threat to aquaculture and fisheries

inferred← citeshttps://doi.org/10.1016/j.envpol.2024.123835openalex-snapshot

Mixture toxicity of 6PPD-quinone and polystyrene nanoplastics in zebrafish

inferred← citeshttps://doi.org/10.1016/j.envpol.2024.123872openalex-snapshot

6PPDQ induces cardiomyocyte senescence via AhR/ROS-mediated autophagic flux blockage

inferred← citeshttps://doi.org/10.1016/j.envpol.2024.124600openalex-snapshot

Exposure to 6-PPD quinone enhances glycogen accumulation in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.envpol.2025.125780openalex-snapshot

Effects of tire particles on earthworm (Eisenia andrei) fitness and bioaccumulation of tire-related chemicals

inferred← citeshttps://doi.org/10.1016/j.envpol.2025.125785openalex-snapshot

6-PPD triggered lipid metabolism disorder and inflammatory response in larval zebrafish (Danio rerio) by regulating PPARγ/NF-κB pathway

inferred← citeshttps://doi.org/10.1016/j.envpol.2025.126352openalex-snapshot

Environmental fate, toxicity, and mitigation of 6PPD and 6PPD-Quinone: Current understanding and future directions

inferred← citeshttps://doi.org/10.1016/j.envpol.2026.128111openalex-snapshot

Uptake, metabolism, and transcriptome responses to 6PPD-Quinone in germinating Ipomoea aquatica

inferred← citeshttps://doi.org/10.1016/j.envres.2026.123840openalex-snapshot

Prenatal exposure to tire-derived chemical mixtures and childhood neurodevelopment at 2 years: Integrating mixture and single-pollutant models

inferred← citeshttps://doi.org/10.1016/j.envres.2026.124637openalex-snapshot

Exposure to 6-PPD quinone inhibits ATP synthesis by causing damage on mitochondrial complex V in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.ese.2025.100567openalex-snapshot

Chronic toxicity mechanisms of 6PPD and 6PPD-Quinone in zebrafish

inferred← citeshttps://doi.org/10.1016/j.fct.2026.116056openalex-snapshot

6PPD-quinone promotes ovarian cancer progression: Insights from network toxicology, machine learning, and in vitro validation

inferred← citeshttps://doi.org/10.1016/j.fochx.2026.104100openalex-snapshot

Para-phenylenediamines and their oxidative derivatives in infant formulas in China: Occurrence and health implications

inferred← citeshttps://doi.org/10.1016/j.hazadv.2026.101572openalex-snapshot

Automated high-throughput behavioral phenotyping reveals subtle ecotoxicity of tire wear particles in Drosophila larvae

inferred← citeshttps://doi.org/10.1016/j.jare.2025.03.033openalex-snapshot

Inhalation exposure to tire rubber particle-sourced pollutant 6PPD-quinone involving basolateral amygdala impairment in male ICR mice

inferred← citeshttps://doi.org/10.1016/j.jece.2026.123090openalex-snapshot

Trophic transfer and toxicity of 6PPD-quinone in an aquatic food chain: Role of uptake routes

inferred← citeshttps://doi.org/10.1016/j.jece.2026.125200openalex-snapshot

Environmental occurrence, fate and ecological toxicity of tire-derived 6PPD and 6PPD-Q in earthworms: Insights into gut dysbiosis and potential ARG dissemination risks

inferred← citeshttps://doi.org/10.1016/j.jenvman.2026.130197openalex-snapshot

Characterization and risk of PPDs and PPD-Qs in an abandoned rubber antioxidant production site

inferred← citeshttps://doi.org/10.1016/j.jep.2025.119721openalex-snapshot

Niuhuang jiedu prescription alleviates realgar-induced dopaminergic and GABAergic neurotoxicity in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jes.2025.11.004openalex-snapshot

Exposure to 6-PPD quinone suppresses the proliferation and differentiation of osteoblasts by Nr4a1-p38 MAPK signal axis

inferred← citeshttps://doi.org/10.1016/j.jes.2025.12.032openalex-snapshot

Environmental levels of 6PPD and 6PPD-Q induced neurotoxicity in zebrafish: Insights from molecular dynamics simulation, neurotransmitters, and transcriptomic analysis

inferred← citeshttps://doi.org/10.1016/j.jes.2026.02.051openalex-snapshot

Impairment of pentose phosphate pathway mediates 6-PPD quinone-induced neurotoxicity by inhibiting NADPH-dependent antioxidant defense

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2023.132265openalex-snapshot

Tire-rubber related pollutant 6-PPD quinone: A review of its transformation, environmental distribution, bioavailability, and toxicity

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2023.133312openalex-snapshot

6PPD-quinone exposure induces neuronal mitochondrial dysfunction to exacerbate Lewy neurites formation induced by α-synuclein preformed fibrils seeding

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.133545openalex-snapshot

Comparison of reproductive toxicity between pristine and aged polylactic acid microplastics in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.134165openalex-snapshot

Chronic exposure to tire rubber-derived contaminant 6PPD-quinone impairs sperm quality and induces the damage of reproductive capacity in male mice

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.134356openalex-snapshot

Exposure to 6-PPD quinone causes ferroptosis activation associated with induction of reproductive toxicity in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.134598openalex-snapshot

Exposure to 6-PPD quinone causes damage on mitochondrial complex I/II associated with lifespan reduction in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.134730openalex-snapshot

Polymer chain extenders induce significant toxicity through DAF-16 and SKN-1 pathways in Caenorhabditis elegans: A comparative analysis

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.135938openalex-snapshot

Environmentally relevant concentrations of perfluorobutane sulfonate impair locomotion behaviors and healthspan by downregulating mitophagy in C. elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.135995openalex-snapshot

Stress of soil moisture and temperature exacerbates the toxicity of tire wear particles to soil fauna: Tracking the role of additives through host microbiota

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.136099openalex-snapshot

Accurate and stable detection of p-phenylenediamine antioxidants and their transformation products in aquatic products using antioxidant protection – Analysis of actual aquatic products

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.136155openalex-snapshot

Unveiling the environmental impact of tire wear particles and the associated contaminants: A comprehensive review of environmental and health risk

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.137000openalex-snapshot

Environmental factors ultraviolet a and ozone exacerbate the repeated inhalation toxicity of 6PPD in mice via accelerating the aging reaction

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2024.137037openalex-snapshot

Exposure to 6PPD-Q induces dysfunctions of ovarian granulosa cells: Its potential role in PCOS

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.137373openalex-snapshot

p-Phenylenediamines and their derived quinones: A review of their environmental fate, human exposure, and biological toxicity

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.137821openalex-snapshot

Identification of cell-surface receptors associated with 6-PPD quinone-induced reproductive toxicity in Caenorhabditis elegans after long-term and low-dose exposure: A primordial response including sword effect and shield effect

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139277openalex-snapshot

Respiratory exposure to 6PPD-quinone aggravates Klebsiella pneumoniae pneumonia by impairing the innate immune function of alveolar macrophages

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.139650openalex-snapshot

Gut-brain axis dysfunction mediates neurotoxicity of embryonic p-phenylenediamine exposure in zebrafish

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.140332openalex-snapshot

6-PPD induces mitochondrial dysfunction and reduces healthspan and lifespan through SKN-1 in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2025.140527openalex-snapshot

Earthworm intestine orchestrates dual host-microbiome detoxification of 6PPD-quinone

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.142781openalex-snapshot

6PPD-quinone induces systemic and transgenerational effects in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.143190openalex-snapshot

Combined thermal and 6PPD-quinone stressors alter biological endpoints, oxidative stress responses, and transcriptomic profiles in the rotifer Brachionus plicatilis

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.143254openalex-snapshot

The emergence of rubber-derived quinones in environment: From Evidence-based toxicological views to policy interventions

inferred← citeshttps://doi.org/10.1016/j.jhazmat.2026.143469openalex-snapshot

Accelerated transformation and enhanced gastrointestinal toxicity of tire wear particles during photo-chlorination mediated by reactive species

inferred← citeshttps://doi.org/10.1016/j.jwpe.2026.110733openalex-snapshot

Tire wear particles in the environment: A critical review on key challenges and future perspectives in fate, risk, and mitigation

inferred← citeshttps://doi.org/10.1016/j.marenvres.2026.108056openalex-snapshot

Occurrence and distribution of waterborne substituted p-phenylenediamine antioxidants and their derivatives in coastal areas of China

inferred← citeshttps://doi.org/10.1016/j.neuro.2026.103491openalex-snapshot

Combined exposure to 6PPD and 6PPD-Q induced neurotoxic responses in zebrafish and SH-SY5Y cells: Evidence from neurotransmitter disruption, oxidative damage, and apoptosis

inferred← citeshttps://doi.org/10.1016/j.pestbp.2025.106829openalex-snapshot

Avermectin and cyclobutrifluram cause oxidative stress and energy metabolic disorders of Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.scib.2023.12.045openalex-snapshot

Neurological impairment is crucial for tire rubber-derived contaminant 6PPDQ-induced acute toxicity to rainbow trout

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.164842openalex-snapshot

Four-week repeated exposure to tire-derived 6-PPD quinone causes multiple organ injury in male BALB/c mice

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.167471openalex-snapshot

Polyethylene nanoplastics cause reproductive toxicity associated with activation of both estrogenic hormone receptor NHR-14 and DNA damage checkpoints in C. elegans

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.167820openalex-snapshot

Environmentally relevant exposure to tetrabromobisphenol A induces reproductive toxicity via regulating glucose-6-phosphate 1-dehydrogenase and sperm activation in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2023.169291openalex-snapshot

Stable isotope-assisted mass spectrometry reveals in vivo distribution, metabolism, and excretion of tire rubber-derived 6PPD-quinone in mice

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.170679openalex-snapshot

Environmentally realistic dose of tire-derived metabolite 6PPD-Q exposure causes intestinal jejunum and ileum damage in mice via cannabinoid receptor-activated inflammation

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.170760openalex-snapshot

Polyethylene nanoparticles at environmentally relevant concentrations enhances neurotoxicity and accumulation of 6-PPD quinone in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.171220openalex-snapshot

Evaluation of 6-PPD quinone toxicity on lung of male BALB/c mice by quantitative proteomics

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.171291openalex-snapshot

Long-term exposure to 6-PPD quinone at environmentally relevant concentrations causes neurotoxicity by affecting dopaminergic, serotonergic, glutamatergic, and GABAergic neuronal systems in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.172306openalex-snapshot

Comparison of intestinal toxicity in enhancing intestinal permeability and in causing ROS production of six PPD quinones in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.174449openalex-snapshot

P-phenylenediamine antioxidants and their quinone derivatives: A review of their environmental occurrence, accessibility, potential toxicity, and human exposure

inferred← citeshttps://doi.org/10.1016/j.tox.2025.154091openalex-snapshot

6PPD induces apoptosis and autophagy in SH-SY5Y cells via ROS-mediated PI3K/AKT/mTOR pathway: In vitro and in silico approaches

inferred← citeshttps://doi.org/10.1016/j.watres.2024.122408openalex-snapshot

Development and application of diffusive gradients in thin-films for in-situ monitoring of 6PPD-Quinone in urban waters

inferred← citeshttps://doi.org/10.1021/acs.est.3c05026openalex-snapshot

Urine Excretion, Organ Distribution, and Placental Transfer of 6PPD and 6PPD-Quinone in Mice and Potential Developmental Toxicity through Nuclear Receptor Pathways

inferred← citeshttps://doi.org/10.1021/acs.est.3c05325openalex-snapshot

Exposure to 6-PPD Quinone at Environmentally Relevant Concentrations Inhibits Both Lifespan and Healthspan in C. elegans

inferred← citeshttps://doi.org/10.1021/acs.est.4c00027openalex-snapshot

Fragmentation Pattern-Based Screening Strategy Combining Diagnostic Ion and Neutral Loss Uncovered Novel para-Phenylenediamine Quinone Contaminants in the Environment

inferred← citeshttps://doi.org/10.1021/acs.est.4c03552openalex-snapshot

Nontarget Analysis of Legacy and Emerging PFAS in a Lithium-Ion Power Battery Recycling Park and Their Possible Toxicity Measured Using High-Throughput Phenotype Screening

inferred← citeshttps://doi.org/10.1021/acs.est.4c04693openalex-snapshot

Characterizing the Metabolism of Tire Rubber-Derived p-Phenylenediamine Quinones to Identify Potential Exposure Biomarkers in Humans

inferred← citeshttps://doi.org/10.1021/acs.est.4c06357openalex-snapshot

Environmentally Relevant Concentrations of S-6PPD-Quinone Caused More Serious Hepatotoxicity Than R-Enantiomer and Racemate in Oncorhynchus mykiss

inferred← citeshttps://doi.org/10.1021/acs.est.4c07783openalex-snapshot

Diquat Induces Cell Death and dopamine Neuron Loss via Reactive Oxygen Species Generation in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1021/acs.est.4c09276openalex-snapshot

Long-Term Exposure to Tire-Derived 6-PPD Quinone Causes Neurotoxicity and Neuroinflammation via Inhibition of HTR2A in C57BL/6 Mice

inferred← citeshttps://doi.org/10.1021/acs.est.4c13830openalex-snapshot

Tire Rubber Antioxidant 6PPD and 6PPD-quinone Disrupt the Energy Supply and Lipid Metabolism of Earthworms

inferred← citeshttps://doi.org/10.1021/acs.est.5c02319openalex-snapshot

6:2 Chlorinated Polyfluoroalkyl Ether Sulfonate (F-53B) Induces Aging and Parkinson’s Disease-like Disorders in C. elegans at Low Concentrations

inferred← citeshttps://doi.org/10.1021/acs.est.5c06619openalex-snapshot

In-Depth Investigation into the Neurotoxic and Neuroglioma Risks of 6PPD Exposure in Zebrafish Larvae: Benchmark Dose Analysis, Molecular Mechanisms, and Adult Pathological Effects

inferred← citeshttps://doi.org/10.1021/acs.est.5c12242openalex-snapshot

Spatiotemporal Distribution of 6PPD-Q in China Revealed by a National-Scale Quantification Framework

inferred← citeshttps://doi.org/10.1021/acs.est.5c12923openalex-snapshot

Occurrence, Transformation, and Toxicity of Tire-Derived Chemicals 6PPD and 6PPD-q in the Environment

inferred← citeshttps://doi.org/10.1021/acs.est.5c16686openalex-snapshot

Chemoproteomic Profiling Reveals 6PPDQ-Mediated Neurotoxicity in Rainbow Trout through Disruption of the Glutamate–Glutamine Cycle

inferred← citeshttps://doi.org/10.1021/acs.estlett.6c00044openalex-snapshot

Light Aging of Plastic Films Causes Nerve Damage Due to the Additives Released into the Water

inferred← citeshttps://doi.org/10.1021/acs.jafc.5c14862openalex-snapshot

Investigation of the Inhibition of IRE-1/XBP-1 Pathway in the Multiple Nematicidal Mechanisms of Isobavachalcone against Meloidogyne incognita

inferred← citeshttps://doi.org/10.1021/acs.jafc.5c15430openalex-snapshot

Ecological Risk Assessment for Six Pesticides in Farmland and Surface Water Ecosystems

inferred← citeshttps://doi.org/10.1021/acs.jafc.6c05811openalex-snapshot

Behavioral Effects and Potential Mechanisms of Imidacloprid- and Flupyradifurone-Induced Neurotoxicity in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1021/acsestwater.3c00275openalex-snapshot

Automated, High-Throughput Analysis of Tire-Derived p -Phenylenediamine Quinones (PPDQs) in Water by Online Membrane Sampling Coupled to MS/MS

inferred← citeshttps://doi.org/10.1021/acsnano.4c08516openalex-snapshot

Putative Adverse Outcome Pathway for Parkinson’s Disease-like Symptoms Induced by Silicon Quantum Dots based on In Vivo/Vitro Approaches

inferred← citeshttps://doi.org/10.1039/d4sc01423eopenalex-snapshot

Charge-regulated fluorescent anchors enable high-fidelity tracking of plasma membrane dynamics during biological events

inferred← citeshttps://doi.org/10.1039/d5em00224aopenalex-snapshot

An environmentally relevant concentration of 6-PPD quinone inhibits two types of mitophagy to cause mitochondrial dysfunction and lifespan reduction in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.1080/2833373x.2026.2650933openalex-snapshot

A piece of the ecotoxicology puzzle: how can current and future research inform PPD regulations?

inferred← citeshttps://doi.org/10.20517/jeea.2025.66openalex-snapshot

6-PPD quinone-inhibited retinoic acid synthesis mediates toxicity through feedback loop between ALH-3/DHS-19-SEX-1 axis and intestinal signals in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.2139/ssrn.5348234openalex-snapshot

Multi-Omics Analysis Reveals the Role of Tire Particles in the Mechanism of Neurodegeneration

inferred← citeshttps://doi.org/10.2139/ssrn.5777595openalex-snapshot

Tire Derived 6PPD-Quinone in Ipomoea aquatica during Germination: Uptake, Metabolism, and Transcriptome Responses

inferred← citeshttps://doi.org/10.2139/ssrn.6617712openalex-snapshot

Mechanisms of Chloride Enhanced Electrochemical Degradation of 6PPD-Q: The Role of Reactive Chlorine Species and Chlorinated Products Formation

inferred← citeshttps://doi.org/10.2139/ssrn.6636669openalex-snapshot

Impact of Tyre Rubber Leachates on Freshwater Gastropods: Behavioural and Developmental Effects on Physella acuta

inferred← citeshttps://doi.org/10.3389/fphar.2023.1202379openalex-snapshot

Paeoniflorin mitigates high glucose-induced lifespan reduction by inhibiting insulin signaling in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.3390/toxics11060511openalex-snapshot

Sulfonate-Modified Polystyrene Nanoparticle at Precited Environmental Concentrations Induces Transgenerational Toxicity Associated with Increase in Germline Notch Signal of Caenorhabditis elegans

inferred← citeshttps://doi.org/10.3390/toxics11080653openalex-snapshot

Combined Effects of Micro- and Nanoplastics at the Predicted Environmental Concentration on Functional State of Intestinal Barrier in Caenorhabditis elegans

inferred← citeshttps://doi.org/10.3390/toxics13040301openalex-snapshot

Review of Health Effects of Automotive Brake and Tyre Wear Particles

inferred← citeshttps://doi.org/10.3390/toxics13100873openalex-snapshot

Environmental and Human Health Risks of 6PPD and 6PPDQ: Assessment and Implications

inferred← citeshttps://doi.org/10.3390/toxics13110906openalex-snapshot

Environmental Occurrence, Influencing Factors, and Toxic Effects of 6PPD-Q

Editorial review for independent work. ICSAC — the Institute for Complexity Science and Advanced Computing — runs a structured editorial panel for researchers publishing outside journals, and publishes on CiteStamp rails. Submission is free and goes through ORCID: icsacinstitute.org/submit.