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Isolation of Premyrsinane, Myrsinane, and Tigliane Diterpenoids from Euphorbia pithyusa Using a Chikungunya Virus Cell-Based Assay and Analogue Annotation by Molecular Networking

https://doi.org/10.1021/acs.jnatprod.7b00233

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Proposed minimum reporting standards for chemical analysis

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Four diterpene esters from Euphorbia myrsinites

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Diterpenes from euphorbia seguieriana

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Protein kinases C as potential host targets for the inhibition of chikungunya virus replication

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Chikungunya virus: an update on antiviral development and challenges

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Tigliane diterpenes from Croton mauritianus as inhibitors of chikungunya virus replication

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LC-MS2-Based dereplication of Euphorbia extracts with anti-Chikungunya virus activity

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Dual mechanism of action of ingenol mebutate gel for topical treatment of actinic keratoses: Rapid lesion necrosis followed by lesion-specific immune response

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Antiviral chlorinated daphnane diterpenoid orthoesters from the bark and wood of Trigonostemon cherrieri

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Cyclomyrsinane and premyrsinane diterpenes from Euphorbia falcata modulate resistance of cancer cells to doxorubicin

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Molecular Networking As a Drug Discovery, Drug Metabolism, and Precision Medicine Strategy

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US Military contributions to the global response to pandemic chikungunya

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The Caribbean response to chikungunya

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Antiviral Activity of Diterpene Esters on Chikungunya Virus and HIV Replication

inferredcites →https://doi.org/10.1021/acs.jnatprod.5b00116openalex-snapshot

Antiviral Activity of Flexibilane and Tigliane Diterpenoids from Stillingia lineata

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Simplified Bryostatin Analogues Protect Cells from Chikungunya Virus-Induced Cell Death

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Inhibition of Chikungunya Virus-Induced Cell Death by Salicylate-Derived Bryostatin Analogues Provides Additional Evidence for a PKC-Independent Pathway

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Myrsinane, Premyrsinane, and Cyclomyrsinane Diterpenes from Euphorbia falcata as Potassium Ion Channel Inhibitors with Selective G Protein-Activated Inwardly Rectifying Ion Channel (GIRK) Blocking Effects

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ChemCalc: A Building Block for Tomorrow’s Chemical Infrastructure

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Chemical and Pharmacological Research of the Plants in Genus Euphorbia

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Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)

inferredcites →https://doi.org/10.1021/jm400460dopenalex-snapshot

Chikungunya Virus: Emerging Targets and New Opportunities for Medicinal Chemistry

inferredcites →https://doi.org/10.1021/np200591hopenalex-snapshot

Bioactive Myrsinol Diterpenoids from the Roots of Euphorbia prolifera

inferredcites →https://doi.org/10.1021/np300637topenalex-snapshot

Prostratin and 12-O-Tetradecanoylphorbol 13-Acetate Are Potent and Selective Inhibitors of Chikungunya Virus Replication

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Molecular Networking as a Dereplication Strategy

inferredcites →https://doi.org/10.1021/np500271uopenalex-snapshot

Jatrophane Diterpenes as Inhibitors of Chikungunya Virus Replication: Structure–Activity Relationship and Discovery of a Potent Lead

inferredcites →https://doi.org/10.1021/np990209uopenalex-snapshot

Diterpenoids from Euphorbia pithyusa subsp. cupanii

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US assesses virus of the Caribbean

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Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

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Biologically active diterpenes containing a gem-dimethylcyclopropane subunit: an intriguing source of PKC modulators

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Pre-myrsinanes and deoxygenated phorboids from the Iranian spurge Euphorbia macroclada Boiss.

inferredcites →https://doi.org/10.1101/gr.1239303openalex-snapshot

Cytoscape: A Software Environment for Integrated Models of Biomolecular Interaction Networks

inferredcites →https://doi.org/10.1111/1469-0691.12694openalex-snapshot

Globalization of Chikungunya: 10 years to invade the world

inferredcites →https://doi.org/10.1111/evo.12534openalex-snapshot

Evolutionary bursts in Euphorbia (Euphorbiaceae) are linked with photosynthetic pathway

inferredcites →https://doi.org/10.1111/j.1095-8339.1987.tb01036.xopenalex-snapshot

The saga of the spurges: a review of classification and relationships in the Euphorbiales

inferredcites →https://doi.org/10.2147/vdt.s25513openalex-snapshot

Current research and clinical trials for a vaccine against Chikungunya virus

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Concurrent outbreaks of dengue, chikungunya and Zika virus infections – an unprecedented epidemic wave of mosquito-borne viruses in the Pacific 2012–2014

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Trigocherrierin A, a Potent Inhibitor of Chikungunya Virus Replication

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Emerging and re-emerging viruses: A global challenge illustrated by Chikungunya virus outbreaks

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Why do Euphorbiaceae tick as medicinal plants? A review of Euphorbiaceae family and its medicinal features

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Bioactive Diterpenoids from the Stems of Euphorbia antiquorum

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Pepluanols C–D, Two Diterpenoids with Two Skeletons from Euphorbia peplus

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