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Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)

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Structural characterization and dynamic NMR studies of a new peracylated macrocyclic diterpene
inferredcites →https://doi.org/10.1002/ejoc.201200733openalex-snapshot
Diterpenes from European Euphorbia Species Serving as Prototypes for Natural‐Product‐Based Drug Discovery
inferredcites →https://doi.org/10.1002/hlca.200390282openalex-snapshot
Isolation and Structure Determination of New Jatrophane Diterpenoids from Euphorbia platyphyllos L.
inferredcites →https://doi.org/10.1002/hlca.200590124openalex-snapshot
Toward a Total Synthesis of Macrocyclic Jatrophane Diterpenes – Concise Route to a Highly Functionalized Cyclopentane Key Intermediate
inferredcites →https://doi.org/10.1002/hlca.200900288openalex-snapshot
New Cytotoxic Myrsinane‐Type Diterpenes from Euphorbia prolifera
inferredcites →https://doi.org/10.1002/hlca.200900353openalex-snapshot
Three New Diterpenoids from Euphorbia sororia L.
inferredcites →https://doi.org/10.1002/hlca.201200092openalex-snapshot
Bisyinshanic Acids A and B, Two Novel Diterpene Dimers from the Roots of Euphorbia yinshanica
inferredcites →https://doi.org/10.1002/jcb.23021openalex-snapshot
Euphorbia factor L1 reverses ABCB1‐mediated multidrug resistance involving interaction with ABCB1 independent of ABCB1 downregualtion
inferredcites →https://doi.org/10.1007/s10059-011-0137-0openalex-snapshot
Jolkinolide B from Euphorbia fischeriana Steud Induces Apoptosis in Human Leukemic U937 Cells through PI3K/Akt and XIAP Pathways
inferredcites →https://doi.org/10.1007/s11101-009-9126-8openalex-snapshot
Jatrophane diterpenes from Euphorbia spp. as modulators of multidrug resistance in cancer therapy
inferredcites →https://doi.org/10.1007/s11418-009-0366-0openalex-snapshot
Bioassay-guided separation of the proinflammatory constituents from the roots of Euphorbia kansui
inferredcites →https://doi.org/10.1007/s11418-012-0688-1openalex-snapshot
Four new myrsinol diterpenes from Euphorbia prolifera
inferredcites →https://doi.org/10.1007/s12272-001-2149-3openalex-snapshot
Cytotoxic macrocyclic diterpenoids from Euphorbia helioscopia
inferredcites →https://doi.org/10.1016/0031-9422(92)83710-gopenalex-snapshot
Jatrophane and lathyrane diterpenoid esters from north american leafy spurge seed
inferredcites →https://doi.org/10.1016/0040-4020(89)80132-2openalex-snapshot
Total synthesis of (±)−jolkinolide A, B, and E utilizing a new mild esterification followsd by intramolecular Wittig-Horner reaction
inferredcites →https://doi.org/10.1016/0738-081x(86)90062-3openalex-snapshot
Irritant plants in the spurge family (Euphorbiaceae)
inferredcites →https://doi.org/10.1016/j.aspen.2009.09.002openalex-snapshot
Pesticidal activity of ingenane diterpenes isolated from Euphorbia kansui against Nilaparvata lugens and Tetranychus urticae
inferredcites →https://doi.org/10.1016/j.bcp.2008.11.025openalex-snapshot
SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro
inferredcites →https://doi.org/10.1016/j.bmc.2005.10.059openalex-snapshot
Inhibition of cellular proliferation by diterpenes, topoisomerase II inhibitor
inferredcites →https://doi.org/10.1016/j.bmc.2006.09.028openalex-snapshot
Apoptosis induction and modulation of P-glycoprotein mediated multidrug resistance by new macrocyclic lathyrane-type diterpenoids
inferredcites →https://doi.org/10.1016/j.bmc.2008.08.071openalex-snapshot
Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells
inferredcites →https://doi.org/10.1016/j.bmc.2009.04.041openalex-snapshot
Lathyrane diterpenes from Euphorbia lathyris as modulators of multidrug resistance and their crystal structures
inferredcites →https://doi.org/10.1016/j.bmcl.2007.05.072openalex-snapshot
Paraliane and pepluane diterpenes as anti-inflammatory agents: First insights in structure–activity relationships
inferredcites →https://doi.org/10.1016/j.bmcl.2012.04.052openalex-snapshot
New myrsinol diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production
inferredcites →https://doi.org/10.1016/j.bse.2009.04.003openalex-snapshot
Ent-abietane diterpenoids from Euphorbia guyoniana Boiss. & Reut.
inferredcites →https://doi.org/10.1016/j.cclet.2009.09.013openalex-snapshot
A new diterpenoid from Euphorbia helioscopia
inferredcites →https://doi.org/10.1016/j.cclet.2009.10.002openalex-snapshot
A new lathyrane diterpene glycoside from Euphorbia helioscopia L.
inferredcites →https://doi.org/10.1016/j.cclet.2010.04.024openalex-snapshot
Kansuinine J, a new macrocyclic diterpenoid from the roots of Euphorbia kansui
inferredcites →https://doi.org/10.1016/j.cellbi.2003.11.017openalex-snapshot
Selective inhibition of the growth of cancer cells by diterpenes selected with embryonic cells of Xenopus
inferredcites →https://doi.org/10.1016/j.ejmech.2007.03.016openalex-snapshot
Anti-tumor 12-deoxyphorbol esters from Euphorbia cornigera
inferredcites →https://doi.org/10.1016/j.ejmech.2009.03.019openalex-snapshot
Bio-active compounds from Euphorbia cornigera Boiss
inferredcites →https://doi.org/10.1016/j.eururo.2006.04.006openalex-snapshot
Effect of Intravesical Resiniferatoxin (RTX) on Lower Urinary Tract Symptoms, Urodynamic Parameters, and Quality of Life of Patients with Urodynamic Increased Bladder Sensation
inferredcites →https://doi.org/10.1016/j.fct.2011.09.035openalex-snapshot
New anti-cancer characteristics of jatrophane diterpenes from Euphorbia dendroides
inferredcites →https://doi.org/10.1016/j.fitote.2008.01.008openalex-snapshot
Two new diterpenes from Euphorbia kansuensis
inferredcites →https://doi.org/10.1016/j.fitote.2009.06.014openalex-snapshot
A new cytotoxic casbane diterpene from Euphorbia pekinensis
inferredcites →https://doi.org/10.1016/j.fitote.2010.05.015openalex-snapshot
Diterpenoid (poly)esters and a ring A-seco-phorboid from the aerial parts of Euphorbia macroclada Boiss
inferredcites →https://doi.org/10.1016/j.fitote.2010.05.017openalex-snapshot
Two new lathyrane type diterpenoids from Euphorbia aellenii
inferredcites →https://doi.org/10.1016/j.fitote.2010.10.015openalex-snapshot
Macrocyclic diterpenoids from the Iranian plant Euphorbia bungei Boiss.
inferredcites →https://doi.org/10.1016/j.fitote.2011.10.020openalex-snapshot
Comparative characteristic of the inflammatory diterpenes in the roots of Euphorbia fischeriana with different preparation method using HPLC–ELSD
inferredcites →https://doi.org/10.1016/j.fitote.2012.06.014openalex-snapshot
Lathyrane diterpenes from Euphorbia prolifera and their inhibitory activities on LPS-induced NO production
inferredcites →https://doi.org/10.1016/j.intimp.2011.10.020openalex-snapshot
17-Hydroxy-jolkinolide B, a diterpenoid from Euphorbia fischeriana, inhibits inflammatory mediators but activates heme oxygenase-1 expression in lipopolysaccharide-stimulated murine macrophages
inferredcites →https://doi.org/10.1016/j.jaad.2009.01.008openalex-snapshot
Randomized, double-blind, double-dummy, vehicle-controlled study of ingenol mebutate gel 0.025% and 0.05% for actinic keratosis
inferredcites →https://doi.org/10.1016/j.phymed.2009.07.009openalex-snapshot
Antitumor activity of terpenoids against classical and atypical multidrug resistant cancer cells
inferredcites →https://doi.org/10.1016/j.phytochem.2003.08.021openalex-snapshot
Secondary metabolites from the liverwort Tylimanthus renifolius
inferredcites →https://doi.org/10.1016/j.phytochem.2007.09.013openalex-snapshot
Ingenane diterpenoids from Euphorbia esula
inferredcites →https://doi.org/10.1016/j.phytochem.2009.10.003openalex-snapshot
Bioactive jatrophane diterpenes from Euphorbia guyoniana
inferredcites →https://doi.org/10.1016/j.phytochem.2009.10.005openalex-snapshot
Effects of diterpenes from latex of Euphorbia lactea and Euphorbia laurifolia on human immunodeficiency virus type 1 reactivation
inferredcites →https://doi.org/10.1016/j.phytochem.2011.11.016openalex-snapshot
Diterpenoids from Euphorbia neriifolia
inferredcites →https://doi.org/10.1016/j.phytol.2010.05.003openalex-snapshot
Jatrophane diterpenoids from Fructus Euphorbia sororia
inferredcites →https://doi.org/10.1016/j.tet.2005.10.035openalex-snapshot
Synthetic approaches to ingenol
inferredcites →https://doi.org/10.1016/j.tet.2006.11.083openalex-snapshot
Diastereoselective synthesis of antiquorin and related polyoxygenated atisene-type diterpenes
inferredcites →https://doi.org/10.1016/j.tet.2011.07.051openalex-snapshot
New premyrsinane-type diterpene polyesters from Euphorbia falcata
inferredcites →https://doi.org/10.1016/j.tet.2011.11.039openalex-snapshot
Cyclomyrsinane and premyrsinane diterpenes from Euphorbia falcata modulate resistance of cancer cells to doxorubicin
inferredcites →https://doi.org/10.1016/j.tetlet.2003.10.171openalex-snapshot
Enantioselective synthesis of the C-14 to C-5 cyclopentane segment of jatrophane diterpenes
inferredcites →https://doi.org/10.1016/j.tetlet.2007.06.046openalex-snapshot
Concise synthesis of a highly functionalized cyclopentane segment: toward the total synthesis of kansuinine A
inferredcites →https://doi.org/10.1016/j.tetlet.2012.03.080openalex-snapshot
Efforts toward the total synthesis of a jatrophane diterpene
inferredcites →https://doi.org/10.1016/s0031-9422(00)84773-1openalex-snapshot
The characterization of esulone C and chemotaxonomy of jatrophane diterpenes in leafy spurge
inferredcites →https://doi.org/10.1016/s0031-9422(97)00749-8openalex-snapshot
Jatrophane diterpenoids from Euphorbia esula
inferredcites →https://doi.org/10.1016/s0031-9422(97)00831-5openalex-snapshot
Diterpenes from Euphorbia peplus
inferredcites →https://doi.org/10.1016/s0031-9422(97)01037-6openalex-snapshot
Rosane diterpenes and bis-dinorditerpenes from hugonia CASTENEIFOLIAfn2fn2Part 87 in the series Constituents of Tropical Medicinal Plants. For part 86 see Ref. [1].
inferredcites →https://doi.org/10.1016/s0040-4020(00)00982-0openalex-snapshot
Euphosalicin, a new diterpene polyester with multidrug resistance reversing activity from Euphorbia salicifolia
inferredcites →https://doi.org/10.1016/s0040-4039(01)01285-0openalex-snapshot
Salicifoline and salicinolide, new diterpene polyesters from Euphorbia salicifolia
inferredcites →https://doi.org/10.1016/s0040-4039(02)02159-7openalex-snapshot
Construction of the ingenane core using an Fe(III) or Ti(IV) Lewis acid-catalyzed intramolecular [6+4] cycloaddition
inferredcites →https://doi.org/10.1016/s0040-4039(02)02505-4openalex-snapshot
Langduin C, a novel dimeric diterpenoid from the roots of Euphorbia fischeriana
inferredcites →https://doi.org/10.1016/s0040-4039(98)00243-3openalex-snapshot
Synthetic studies on the ingenane diterpenes. Construction of an ABC tricycle exhibiting trans-intrabridgehead stereochemistry
inferredcites →https://doi.org/10.1016/s0092-8674(02)00703-1openalex-snapshot
Missing Pieces in the NF-κB Puzzle
inferredcites →https://doi.org/10.1016/s1572-5995(01)80009-0openalex-snapshot
Labdane-type diterpenes: Chemistry and biological activity
inferredcites →https://doi.org/10.1016/s1875-5364(10)60009-xopenalex-snapshot
A New Jatrophane Diterpenoid from Euphorbia peplus
inferredcites →https://doi.org/10.1016/s1875-5364(10)60013-1openalex-snapshot
Diterpenoids from Euphorbia esula
inferredcites →https://doi.org/10.1021/bi0521745openalex-snapshot
Modulator-Induced Interference in Functional Cross Talk between the Substrate and the ATP Sites of Human P-glycoprotein
inferredcites →https://doi.org/10.1021/ci200145popenalex-snapshot
Toward a Better Pharmacophore Description of P-Glycoprotein Modulators, Based on Macrocyclic Diterpenes fromEuphorbiaSpecies
inferredcites →https://doi.org/10.1021/cr040636zopenalex-snapshot
Total Synthesis of Ingenol
inferredcites →https://doi.org/10.1021/cr078350sopenalex-snapshot
Chemical and Pharmacological Research of the Plants in Genus Euphorbia
inferredcites →https://doi.org/10.1021/ja00168a050openalex-snapshot
Studies on tumor promoters. 9. A second-generation synthesis of phorbol
inferredcites →https://doi.org/10.1021/ja00179a035openalex-snapshot
The total synthesis of (.+-.)-epi-jatrophone and (.+-.)-jatrophone using palladium-catalyzed carbonylative coupling of vinyl triflates with vinyl stannanes as the macrocycle-forming step
inferredcites →https://doi.org/10.1021/ja00243a062openalex-snapshot
Inside-outside stereoisomerism. II. Synthesis of the carbocyclic ring system of the ingenane diterpenes via the intramolecular dioxolenone photocycloaddition
inferredcites →https://doi.org/10.1021/ja00391a054openalex-snapshot
A strategy for the total synthesis of jatrophone: synthesis of normethyljatrophone
inferredcites →https://doi.org/10.1021/ja026600aopenalex-snapshot
The First Total Synthesis of (±)-Ingenol
inferredcites →https://doi.org/10.1021/ja029226nopenalex-snapshot
Total Synthesis of Ingenol
inferredcites →https://doi.org/10.1021/ja044123lopenalex-snapshot
Total Synthesis of Ingenol
inferredcites →https://doi.org/10.1021/jm0111301openalex-snapshot
Discovery and Biological Evaluation of a New Family of Potent Modulators of Multidrug Resistance: Reversal of Multidrug Resistance of Mouse Lymphoma Cells by New Natural Jatrophane Diterpenoids Isolated from Euphorbia Species
inferredcites →https://doi.org/10.1021/jm050321ropenalex-snapshot
Discovery and Biological Evaluation of the Novel Naturally Occurring Diterpene Pepluanone as Antiinflammatory Agent
inferredcites →https://doi.org/10.1021/jo00074a003openalex-snapshot
Stereoselective construction of the complete ingenane ring system
inferredcites →https://doi.org/10.1021/jo048833lopenalex-snapshot
Formal Synthesis of Optically Active Ingenol via Ring-Closing Olefin Metathesis
inferredcites →https://doi.org/10.1021/jo1019738openalex-snapshot
Total Synthesis of Natural and Non-Natural Δ5,6Δ12,13-Jatrophane Diterpenes and Their Evaluation as MDR Modulators
inferredcites →https://doi.org/10.1021/jo802581gopenalex-snapshot
Synthetic Studies toward Jatrophane Diterpenes from Euphorbia characias. Enantioselective Synthesis of (−)-15-O-Acetyl-3-O-propionyl-17-norcharaciol
inferredcites →https://doi.org/10.1021/jo961714oopenalex-snapshot
Synthetic Studies on the Ingenane Diterpenes. Direct Conversion of the out,out-Bicyclo[4.4.1]undecane System into a Highly Strained In,out Stereoisomer
inferredcites →https://doi.org/10.1021/jo970172nopenalex-snapshot
A New Approach for Ingenol Synthesis
inferredcites →https://doi.org/10.1021/np0200921openalex-snapshot
Diterpenes from the Roots of Euphorbia kansui and Their in Vitro Effects on the Cell Division of Xenopus
inferredcites →https://doi.org/10.1021/np0706163openalex-snapshot
Cytotoxic Diterpenoids from Euphorbia helioscopia
inferredcites →https://doi.org/10.1021/np100673sopenalex-snapshot
Unusual Tigliane Diterpenes from Euphorbia grandicornis
inferredcites →https://doi.org/10.1021/np2001489openalex-snapshot
Lathyrane Diterpenoids from the Roots of Euphorbia micractina and Their Biological Activities
inferredcites →https://doi.org/10.1021/np200202hopenalex-snapshot
Jatrophane Diterpenes from Euphorbia esula as Antiproliferative Agents and Potent Chemosensitizers to Overcome Multidrug Resistance
inferredcites →https://doi.org/10.1021/np200241copenalex-snapshot
Isolation and Biological Evaluation of Jatrophane Diterpenoids from Euphorbia dendroides
inferredcites →https://doi.org/10.1021/np200591hopenalex-snapshot
Bioactive Myrsinol Diterpenoids from the Roots of Euphorbia prolifera
inferredcites →https://doi.org/10.1021/np200906sopenalex-snapshot
Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010
inferredcites →https://doi.org/10.1021/np800816nopenalex-snapshot
Ingol and Ingenol Diterpenes from the Aerial Parts of Euphorbia royleana and Their Antiangiogenic Activities
inferredcites →https://doi.org/10.1021/np900127jopenalex-snapshot
Diterpenoids and Triterpenoids from Euphorbia retusa
inferredcites →https://doi.org/10.1021/np960669copenalex-snapshot
Macrocyclic Diterpene Polyesters of the Jatrophane Type from Euphorbia esula
inferredcites →https://doi.org/10.1021/ol0155541openalex-snapshot
Unnatural Natural Products from the Transannular Cyclization of Lathyrane Diterpenes
inferredcites →https://doi.org/10.1021/ol060115topenalex-snapshot
Synthesis of the Norjatrophane Diterpene (−)-15-Acetyl-3-propionyl- 17-norcharaciol
inferredcites →https://doi.org/10.1021/ol900819uopenalex-snapshot
Total Synthesis of Jatrophane Diterpenes from Euphorbia characias
inferredcites →https://doi.org/10.1021/ol902221yopenalex-snapshot
General Synthesis of Highly Functionalized Cyclopentane Segments for the Preparation of Jatrophane Diterpenes
inferredcites →https://doi.org/10.1039/b705652bopenalex-snapshot
Recent advances in the total synthesis of pharmaceutically relevant diterpenes
inferredcites →https://doi.org/10.1039/cs9972600387openalex-snapshot
Approaches to the synthesis of ingenol
inferredcites →https://doi.org/10.1039/p19850002075openalex-snapshot
The absolute stereochemical characterization of two new jatrophane diterpenes from Euphorbia esula
inferredcites →https://doi.org/10.1055/s-0029-1240691openalex-snapshot
Schistosomiasis Suppressing Deoxyphorbol Esters fromEuphorbia cauducifoliaL. Latex
inferredcites →https://doi.org/10.1055/s-0030-1249805openalex-snapshot
Kansuinine A and Kansuinine B fromEuphorbia kansuiL. Inhibit IL-6-induced Stat3 Activation
inferredcites →https://doi.org/10.1055/s-0032-1314975openalex-snapshot
Cycloartane Triterpenes and Ingol Diterpenes Isolated from Euphorbia neriifolia in a Screening Program for Death-Receptor Expression-Enhancing Activity
inferredcites →https://doi.org/10.1055/s-2000-8568openalex-snapshot
Diterpenoids from Euphorbia peplus
inferredcites →https://doi.org/10.1055/s-2002-23135openalex-snapshot
New Macrocyclic Diterpenoids from Euphorbia esula
inferredcites →https://doi.org/10.1055/s-2004-815542openalex-snapshot
Euphopubescenol and Euphopubescene, Two New Jatrophane Polyesters, and Lathyrane-type Diterpenes fromEuphorbia pubescens
inferredcites →https://doi.org/10.1055/s-2006-957574openalex-snapshot
Cytotoxicity and Antiviral Activity of the Compounds fromEuphorbia kansui
inferredcites →https://doi.org/10.1055/s-2007-993765openalex-snapshot
Three New Jatrophane Polyesters and Antiproliferative Constituents from Euphorbia tuckeyana
inferredcites →https://doi.org/10.1080/10286020.2010.489039openalex-snapshot
Irritant and co-carcinogenic diterpene esters from the latex of Euphorbia cauducifolia L.
inferredcites →https://doi.org/10.1080/10286020.2010.512007openalex-snapshot
Isolation and characterization of cytotoxic compounds fromEuphorbia cornigeraBoiss.
inferredcites →https://doi.org/10.1080/10286020.2010.529611openalex-snapshot
New myrsinane-type diterpenoids fromEuphorbia aelleniiRech. f. with their immunomodulatory activity
inferredcites →https://doi.org/10.1080/10286020.2010.532490openalex-snapshot
Diterpenoids from the roots ofEuphorbia fischeriana
inferredcites →https://doi.org/10.1080/10286020600782496openalex-snapshot
A new diterpene from the processed roots of Euphorbia Kansui
inferredcites →https://doi.org/10.1080/14786410903388017openalex-snapshot
New diterpenoids from the roots ofEuphorbia ebracteolataHayata
inferredcites →https://doi.org/10.1097/cad.0b013e3280149ec5openalex-snapshot
Proceedings of the First International Conference on PEP005
inferredcites →https://doi.org/10.1107/s1600536807066901openalex-snapshot
Euphorbiafactor L8: a diterpenoid from the seeds ofEuphorbia lathyris
inferredcites →https://doi.org/10.1111/j.1095-8339.1987.tb01036.xopenalex-snapshot
The saga of the spurges: a review of classification and relationships in the Euphorbiales
inferredcites →https://doi.org/10.1111/j.1095-8339.1987.tb01039.xopenalex-snapshot
Members of Euphorbiaceae in primitive and advanced societies
inferredcites →https://doi.org/10.1111/j.1095-8339.1987.tb01046.xopenalex-snapshot
Tumour promoters of the irritant diterpene ester type as risk factors of cancer in man
inferredcites →https://doi.org/10.1111/j.1095-8339.1987.tb01047.xopenalex-snapshot
The biosynthesis of tigliane and related diterpenoids; an intriguing problem
inferredcites →https://doi.org/10.1111/j.1349-7006.2009.01408.xopenalex-snapshot
Analysis of inhibition of topoisomerase IIα and cancer cell proliferation by ingenolEZ
inferredcites →https://doi.org/10.1111/j.1440-0960.2008.00497.xopenalex-snapshot
PEP005 (ingenol mebutate) gel, a novel agent for the treatment of actinic keratosis: Results of a randomized, double‐blind, vehicle‐controlled, multicentre, phase IIa study
inferredcites →https://doi.org/10.1111/j.1440-0960.2010.00626.xopenalex-snapshot
PEP005 (ingenol mebutate) gel for the topical treatment of superficial basal cell carcinoma: Results of a randomized phase IIa trial
inferredcites →https://doi.org/10.1139/y06-045openalex-snapshot
Induction of apoptosis in K562 cells by jolkinolide B
inferredcites →https://doi.org/10.1158/0008-5472.can-03-3403openalex-snapshot
Characterization of the Interaction of Ingenol 3-Angelate with Protein Kinase C
inferredcites →https://doi.org/10.1158/0008-5472.can-09-0462openalex-snapshot
17-Hydroxy-jolkinolide B Inhibits Signal Transducers and Activators of Transcription 3 Signaling by Covalently Cross-Linking Janus Kinases and Induces Apoptosis of Human Cancer Cells
inferredcites →https://doi.org/10.1158/1535-7163.mct-07-2060openalex-snapshot
Effects of protein kinase C modulation by PEP005, a novel ingenol angelate, on mitogen-activated protein kinase and phosphatidylinositol 3-kinase signaling in cancer cells
inferredcites →https://doi.org/10.1158/1535-7163.mct-08-0263openalex-snapshot
17-Acetoxyjolkinolide B irreversibly inhibits IκB kinase and induces apoptosis of tumor cells
inferredcites →https://doi.org/10.1246/cl.2004.918openalex-snapshot
Total Synthesis of (–)-ent-Jolkinolide D
inferredcites →https://doi.org/10.1248/bpb.29.286openalex-snapshot
3-O-(2,3-Dimethylbutanoyl)-13-O-decanoylingenol from Euphorbia kansui Suppresses IgE-Mediated Mast Cell Activation
inferredcites →https://doi.org/10.1365/s10337-009-1258-xopenalex-snapshot
LC–DAD–ESI-MS–MS Separation and Chemical Characterization of the Inflammatory Fraction of the Roots of Euphorbia kansui
inferredcites →https://doi.org/10.1515/znc-2008-1-211openalex-snapshot
Antinematodal Activities of Ingenane Diterpenes from Euphorbia kansui and their Derivatives against the Pine Wood Nematode (Bursaphelenchus xylophilus)
inferredcites →https://doi.org/10.2174/0929867013373138openalex-snapshot
Structure-Activity Relationships of Multidrug Resistance Reversers
inferredcites →https://doi.org/10.2174/138161206775201893openalex-snapshot
Inhibition of Multidrug Resistance of Cancer Cells by Natural Diterpenes, Triterpenes and Carotenoids
inferredcites →https://doi.org/10.2174/138945011794815266openalex-snapshot
Activation of Latent HIV-1 Expression by Protein Kinase C Agonists. A Novel Therapeutic Approach to Eradicate HIV-1 Reservoirs
inferredcites →https://doi.org/10.2174/156802611796904924openalex-snapshot
Therapeutic Targeting of TRPV1 by Resiniferatoxin, from Preclinical Studies to Clinical Trials
inferredcites →https://doi.org/10.2174/157015908784533888openalex-snapshot
TRPV1: A Target for Next Generation Analgesics
inferredcites →https://doi.org/10.2174/1876386301306010095openalex-snapshot
Resiniferatoxin for Pain Treatment: An Interventional Approach to Personalized Pain Medicine
inferredcites →https://doi.org/10.3390/12030455openalex-snapshot
Occurrence, Biological Activities and Synthesis of Kaurane Diterpenes and their Glycosides
inferredcites →https://doi.org/10.3390/molecules14114454openalex-snapshot
13C-NMR Data of Three Important Diterpenes Isolated from Euphorbia Species
inferredcites →https://doi.org/10.3390/molecules16010466openalex-snapshot
Feeding Deterrents against Two Grain Storage Insects from Euphorbia fischeriana
inferredcites →https://doi.org/10.3390/molecules16043222openalex-snapshot
Structure Identification of Euphorbia Factor L3 and Its Induction of Apoptosis through the Mitochondrial Pathway
inferredcites →https://doi.org/10.3390/molecules17022082openalex-snapshot
Regulated Expressions of MMP-2, -9 by Diterpenoids from Euphorbia formosana Hayata
inferredcites →https://doi.org/10.3390/molecules17089520openalex-snapshot
Three New Myrsinol Diterpenes from Euphorbia prolifera and Their Neuroprotective Activities
inferredcites →https://doi.org/10.3390/toxins2010174openalex-snapshot
The Protein Kinase C Agonist PEP005 (Ingenol 3-Angelate) in the Treatment of Human Cancer: A Balance between Efficacy and Toxicity
inferredcites →https://doi.org/10.3724/sp.j.1009.2010.00081openalex-snapshot
A New Jatrophane Diterpenoid from Euphorbia peplus
inferredcites →https://doi.org/10.3724/sp.j.1009.2010.00094openalex-snapshot
Diterpenoids from Euphorbia esula
inferredcites →https://doi.org/10.3724/sp.j.1009.2010.00101openalex-snapshot
Diterpenes and Triterpenes from the Roots of Euphorbia fischeriana
inferredcites →https://doi.org/10.5897/jmpr.9001179openalex-snapshot
Terpens from aerial parts of Euphorbia splendida.
inferredcites →https://doi.org/10.5897/jmpr.9001294openalex-snapshot
Why do Euphorbiaceae tick as medicinal plants? A review of Euphorbiaceae family and its medicinal features

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112504zenodo-depositor-declared
Bioactive diterpenoid metabolism and cytotoxic activities of genetically transformed Euphorbia lathyris roots
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112519zenodo-depositor-declared
Bond reactivity indices approach analysis of the [2+2] cycloaddition of jatrophane skeleton diterpenoids from Euphorbia gaditana Coss to tetracyclic gaditanone
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112649zenodo-depositor-declared
Euphorbia helioscopia L.: A phytochemical and pharmacological overview
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113106zenodo-depositor-declared
Diverse diterpenoids with α-glucosidase and β-glucuronidase inhibitory activities from Euphorbia milii
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113113zenodo-depositor-declared
Pimarane, abietane, and labdane diterpenoids from Euphorbia pekinensis Rupr. and their anti-tumor activities
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113154zenodo-depositor-declared
Characterization of undescribed melanoma inhibitors from Euphorbia mauritanica L. cultivated in Egypt targeting BRAFV600E and MEK 1 kinases via in-silico study and ADME prediction
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113486zenodo-depositor-declared
Diterpenoids with anti-inflammatory activity from Euphorbia wallichii
inferred← citeshttps://doi.org/10.1002/9781119844792.ch5openalex-snapshot
Deciphering Complex Natural Mixtures through Metabolome Mining of Mass Spectrometry Data
inferred← citeshttps://doi.org/10.1002/ange.201409572openalex-snapshot
Catalytic Asymmetric Intramolecular Homologation of Ketones with α‐Diazoesters: Synthesis of Cyclic α‐Aryl/Alkyl β‐Ketoesters
inferred← citeshttps://doi.org/10.1002/ange.201509160openalex-snapshot
Total Synthesis of Crotophorbolone
inferred← citeshttps://doi.org/10.1002/ange.201704929openalex-snapshot
Diastereoselective Total Synthesis of the Euphorbia Diterpenoid Pepluanol A: A Reductive Annulation Approach
inferred← citeshttps://doi.org/10.1002/ange.201706845openalex-snapshot
Total Syntheses of the Reported Structures of Curcusones I and J through Tandem Gold Catalysis
inferred← citeshttps://doi.org/10.1002/ange.201913645openalex-snapshot
Fragmentverknüpfungen in der Totalsynthese – Bildung von C‐C‐Bindungen über intermediäre Carbanionen oder freie Radikale
inferred← citeshttps://doi.org/10.1002/ange.201915876openalex-snapshot
Total Synthesis of (−)‐Pepluanol B: Conformational Control of the Eight‐Membered‐Ring System
inferred← citeshttps://doi.org/10.1002/ange.202400943openalex-snapshot
Total Synthesis of the Euphorbia Diterpenoid Pepluacetal
inferred← citeshttps://doi.org/10.1002/ange.202409997openalex-snapshot
Asymmetric Total Synthesis of Euphordraculoate A and Pedrolide
inferred← citeshttps://doi.org/10.1002/ange.202522620openalex-snapshot
Energy‐Transfer‐Enabled Skeletal Rearrangement of Cyclic Ketones into Strained Cyclopropane‐Fused Medium Rings
inferred← citeshttps://doi.org/10.1002/anie.201409572openalex-snapshot
Catalytic Asymmetric Intramolecular Homologation of Ketones with α‐Diazoesters: Synthesis of Cyclic α‐Aryl/Alkyl β‐Ketoesters
inferred← citeshttps://doi.org/10.1002/anie.201509160openalex-snapshot
Total Synthesis of Crotophorbolone
inferred← citeshttps://doi.org/10.1002/anie.201704929openalex-snapshot
Diastereoselective Total Synthesis of the Euphorbia Diterpenoid Pepluanol A: A Reductive Annulation Approach
inferred← citeshttps://doi.org/10.1002/anie.201706845openalex-snapshot
Total Syntheses of the Reported Structures of Curcusones I and J through Tandem Gold Catalysis
inferred← citeshttps://doi.org/10.1002/anie.201913645openalex-snapshot
Fragment Coupling Reactions in Total Synthesis That Form Carbon–Carbon Bonds via Carbanionic or Free Radical Intermediates
inferred← citeshttps://doi.org/10.1002/anie.201915876openalex-snapshot
Total Synthesis of (−)‐Pepluanol B: Conformational Control of the Eight‐Membered‐Ring System
inferred← citeshttps://doi.org/10.1002/anie.202400943openalex-snapshot
Total Synthesis of the Euphorbia Diterpenoid Pepluacetal
inferred← citeshttps://doi.org/10.1002/anie.202409997openalex-snapshot
Asymmetric Total Synthesis of Euphordraculoate A and Pedrolide
inferred← citeshttps://doi.org/10.1002/anie.202522620openalex-snapshot
Energy‐Transfer‐Enabled Skeletal Rearrangement of Cyclic Ketones into Strained Cyclopropane‐Fused Medium Rings
inferred← citeshttps://doi.org/10.1002/ardp.70080openalex-snapshot
New Anti‐HIV Agents Isolated From Two Euphorbia Species
inferred← citeshttps://doi.org/10.1002/bmc.70268openalex-snapshot
Comprehensive UHPLC‐ESI‐Orbitrap‐MS Profiling and Bioactivity‐Guided Fractionation of Euphorbia greenwayi : Mechanistic Insights Into Anti‐Inflammatory and Antiaging Bioactive Metabolites
inferred← citeshttps://doi.org/10.1002/cbdv.201400426openalex-snapshot
Polygonifoliol, a New Tirucallane Triterpene from the Latex of the Seaside Sandmat Euphorbia polygonifolia
inferred← citeshttps://doi.org/10.1002/cbdv.201700327openalex-snapshot
New Bioactive Macrocyclic Diterpenoids from Euphorbia helioscopia
inferred← citeshttps://doi.org/10.1002/cbdv.201800144openalex-snapshot
Lathyrane‐Type Diterpenoids from the Seeds of Euphorbia lathyris L. with Inhibitory Effects on NO Production in RAW 264.7 Cells
inferred← citeshttps://doi.org/10.1002/cbdv.201800386openalex-snapshot
Five New Diterpenoids from the Seeds of Euphorbia lathyris
inferred← citeshttps://doi.org/10.1002/cbdv.201900051openalex-snapshot
Chemical Characterization of Euphorbia heterophylla L. Essential Oils and Their Antioxidant Activity and Allelopathic Potential on Cenchrus echinatus L.
inferred← citeshttps://doi.org/10.1002/cbdv.201900495openalex-snapshot
Diterpenoids from Euphorbia neriifolia and Their Related Anti‐HIV and Cytotoxic Activity
inferred← citeshttps://doi.org/10.1002/cbdv.201900531openalex-snapshot
Synthesis of New Lathyrane Diterpenoid Derivatives from Euphorbia lathyris and Evaluation of Their Anti‐Inflammatory Activities
inferred← citeshttps://doi.org/10.1002/cbdv.202000369openalex-snapshot
Enriched Terpenes Fractions of the Latex of Euphorbia umbellata Promote Apoptosis in Leukemic Cells
inferred← citeshttps://doi.org/10.1002/cbdv.202000919openalex-snapshot
Cytotoxic Diterpenoids from Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1002/cbdv.202100238openalex-snapshot
Prevalence of Diterpenes in Essential Oil of Euphorbia mauritanica L.: Detailed Chemical Profile, Antioxidant, Cytotoxic and Phytotoxic Activities
inferred← citeshttps://doi.org/10.1002/cbdv.202200568openalex-snapshot
Bioactive Secondary Plant Metabolites from Euphorbia umbellata (PAX) BRUYNS (Euphorbiaceae)
inferred← citeshttps://doi.org/10.1002/cbdv.202200918openalex-snapshot
Integration of LC/MS, NMR and Molecular Docking for Profiling of Bioactive Diterpenes from Euphorbia mauritanica L. with in Vitro Anti‐SARS‐CoV‐2 Activity
inferred← citeshttps://doi.org/10.1002/cbdv.202301454openalex-snapshot
ent‐Atisane Diterpenoids from Euphorbia helioscopia and Their Anti‐inflammatory Activities
inferred← citeshttps://doi.org/10.1002/cbdv.202400808openalex-snapshot
Abietane‐Type Diterpenoids: Insights into Structural Diversity and Therapeutic Potential
inferred← citeshttps://doi.org/10.1002/cbdv.202500495openalex-snapshot
Lathyrane Diterpenoids From the Roots and Stems of Euphorbia prolifera and Their Anti‐inflammatory Activity
inferred← citeshttps://doi.org/10.1002/chem.201604541openalex-snapshot
Expedient and Diastereodivergent Assembly of Terpenoid Decalin Subunits having Quaternary Stereocenters through Organocatalytic Robinson Annulation of Nazarov Reagent
inferred← citeshttps://doi.org/10.1002/chem.202003221openalex-snapshot
Synthetic Tigliane Intermediates Engage Thiols to Induce Potent Cell Line Selective Anti‐Cancer Activity
inferred← citeshttps://doi.org/10.1002/chem.202003741openalex-snapshot
The Total Synthesis of Diquinane‐Containing Natural Products
inferred← citeshttps://doi.org/10.1002/chir.70061openalex-snapshot
Anti‐Inflammatory Jatrophane Diterpenoids With Multiple Chiral Carbon Centers From Jatropha curcas
inferred← citeshttps://doi.org/10.1002/cjoc.201800199openalex-snapshot
Asymmetric Synthesis of the Ring A Substructure of Genkwadane A
inferred← citeshttps://doi.org/10.1002/cjoc.202400898openalex-snapshot
Total Syntheses of Highly Oxidized Natural Products†
inferred← citeshttps://doi.org/10.1002/ejoc.201403598openalex-snapshot
Progress in the Preparation of Jatrophane Diterpenes
inferred← citeshttps://doi.org/10.1002/fsn3.72244openalex-snapshot
Phytochemical Characterization of Euphorbia peplis Extracts and Their Antioxidant, Enzyme Inhibitory, and Cytotoxic Activities: An Integrated Experimental and In Silico Study
inferred← citeshttps://doi.org/10.1002/med.21816openalex-snapshot
Recent progress and new perspectives for diterpenoid biosynthesis in medicinal plants
inferred← citeshttps://doi.org/10.1002/open.202300243openalex-snapshot
Chemical Profiling and Antioxidant, Antimicrobial, and Hemolytic Properties of Euphorbia calyptrata (l.) Essential oils: in Vitro and in Silico Analysis
inferred← citeshttps://doi.org/10.1002/pca.2711openalex-snapshot
Quantitative Analysis of Ingenol in Euphorbia species via Validated Isotope Dilution Ultra‐high Performance Liquid Chromatography Tandem Mass Spectrometry
inferred← citeshttps://doi.org/10.1002/pca.2776openalex-snapshot
Profiling of Hura crepitans L. latex by ultra‐high‐performance liquid chromatography/atmospheric pressure chemical ionisation linear ion trap Orbitrap mass spectrometry
inferred← citeshttps://doi.org/10.1002/pca.2841openalex-snapshot
Effective MDR reversers through phytochemical study of Euphorbia boetica
inferred← citeshttps://doi.org/10.1007/978-3-030-31269-5_15openalex-snapshot
Therapeutic and Medicinal Uses of Terpenes
inferred← citeshttps://doi.org/10.1007/978-3-030-64853-4_2openalex-snapshot
From Plant to Patient: Thapsigargin, a Tool for Understanding Natural Product Chemistry, Total Syntheses, Biosynthesis, Taxonomy, ATPases, Cell Death, and Drug Development
inferred← citeshttps://doi.org/10.1007/978-3-031-67180-7_1openalex-snapshot
Tigliane Diterpenoids
inferred← citeshttps://doi.org/10.1007/978-3-032-09901-3_1openalex-snapshot
The Diels–Alder Reaction as a Key Step in Natural Product Synthesis
inferred← citeshttps://doi.org/10.1007/978-3-319-31421-1_219-1openalex-snapshot
Microbial Production of Isoprenoids
inferred← citeshttps://doi.org/10.1007/978-3-319-31421-1_219-2openalex-snapshot
Microbial Production of Isoprenoids
inferred← citeshttps://doi.org/10.1007/978-3-319-33172-0_1openalex-snapshot
Ingenane Diterpenoids
inferred← citeshttps://doi.org/10.1007/978-3-319-50436-0_219openalex-snapshot
Microbial Production of Isoprenoids
inferred← citeshttps://doi.org/10.1007/978-3-319-54528-8_58-1openalex-snapshot
Bioactive Lipids
inferred← citeshttps://doi.org/10.1007/978-3-319-67903-7_8openalex-snapshot
Commercial-Scale Tissue Culture for the Production of Plant Natural Products: Successes, Failures and Outlook
inferred← citeshttps://doi.org/10.1007/978-3-319-78030-6_58openalex-snapshot
Bioactive Lipids
inferred← citeshttps://doi.org/10.1007/978-981-13-1745-3_18-1openalex-snapshot
Dietary Diterpenoids
inferred← citeshttps://doi.org/10.1007/978-981-15-4148-3_18openalex-snapshot
Dietary Diterpenoids
inferred← citeshttps://doi.org/10.1007/978-981-19-9605-4_4openalex-snapshot
Secondary Metabolites of Plant Origin in Parasitic Manifestations
inferred← citeshttps://doi.org/10.1007/978-981-99-7329-3_1openalex-snapshot
Introduction
inferred← citeshttps://doi.org/10.1007/s00044-022-02867-1openalex-snapshot
Anti-tumor metabolites from Synadenium grantii Hook F.
inferred← citeshttps://doi.org/10.1007/s10600-023-04091-8openalex-snapshot
A New Diterpenoid with Cytotoxic Activities from the Roots of Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1007/s10787-023-01298-7openalex-snapshot
LC-QToF chemical profiling of Euphorbia grantii Oliv. and its potential to inhibit LPS-induced lung inflammation in rats via the NF-κB, CY450P2E1, and P38 MAPK14 pathways
inferred← citeshttps://doi.org/10.1007/s10886-023-01413-6openalex-snapshot
Defensive Specialized Metabolites from the Latex of Euphorbia jolkinii
inferred← citeshttps://doi.org/10.1007/s11101-016-9472-2openalex-snapshot
Naturally occurring furanoditerpenoids: distribution, chemistry and their pharmacological activities
inferred← citeshttps://doi.org/10.1007/s11101-019-09606-2openalex-snapshot
The landscape of natural product diversity and their pharmacological relevance from a focus on the Dictionary of Natural Products®
inferred← citeshttps://doi.org/10.1007/s11101-020-09667-8openalex-snapshot
Jatrophane and rearranged jatrophane-type diterpenes: biogenesis, structure, isolation, biological activity and SARs (1984–2019)
inferred← citeshttps://doi.org/10.1007/s11101-025-10100-1openalex-snapshot
Diterpenoids from Euphorbia lathyris L.: a comprehensive review update
inferred← citeshttps://doi.org/10.1007/s11295-016-1054-3openalex-snapshot
Genome-wide analysis of the terpene synthase gene family in physic nut (Jatropha curcas L.) and functional identification of six terpene synthases
inferred← citeshttps://doi.org/10.1007/s11418-016-0987-zopenalex-snapshot
Euphorins A–H: bioactive diterpenoids from Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1007/s11626-021-00612-3openalex-snapshot
Jolkinolide B attenuates laryngeal cancer cell growth and induces apoptosis via PTEN/PI3K/Akt signaling pathway
inferred← citeshttps://doi.org/10.1007/s11696-026-05516-8openalex-snapshot
Comprehensive phytochemical and mineral profiling of Euphorbia clementei Boiss. via HPLC-DAD, GC-MS, and ICP-MS: association with in vitro bioactivity
inferred← citeshttps://doi.org/10.1007/s12298-021-01040-zopenalex-snapshot
Genome-wide detection and classification of terpene synthase genes in Aquilaria agallochum
inferred← citeshttps://doi.org/10.1007/s13659-018-0159-9openalex-snapshot
Abietane Diterpernoids from the Roots of Euphorbia ebracteolata
inferred← citeshttps://doi.org/10.1007/s13659-021-00301-4openalex-snapshot
Jatrophane Diterpenoids from the Seeds of Euphorbia peplus with Potential Bioactivities in Lysosomal-Autophagy Pathway
inferred← citeshttps://doi.org/10.1007/s13659-025-00548-1openalex-snapshot
Strophioglandins A–C, highly rearranged norditerpenoids with an unusual tricyclo[6.4.1.04,13]tridecane core from Strophioblachia glandulosa var. cordifolia
inferred← citeshttps://doi.org/10.1007/s43450-025-00731-yopenalex-snapshot
Chemical Constituents of Excoecaria cochinchinensis with Cytotoxic, Antioxidant, Tyrosinase, and α-Glucosidase Inhibitory Activities
inferred← citeshttps://doi.org/10.1016/b978-0-12-816455-6.00009-3openalex-snapshot
Analysis of diterpenes and diterpenoids
inferred← citeshttps://doi.org/10.1016/b978-0-12-817905-5.00009-3openalex-snapshot
Jatrophane diterpenes from Euphorbiaceae family
inferred← citeshttps://doi.org/10.1016/b978-0-12-819541-3.00009-8openalex-snapshot
Potential for cancer treatment: natural products from the Balkans
inferred← citeshttps://doi.org/10.1016/b978-0-12-820237-1.00035-1openalex-snapshot
Euphorbia bicolor (Euphorbiaceae) latex phytochemicals and applications to analgesia
inferred← citeshttps://doi.org/10.1016/b978-0-12-822405-2.00017-7openalex-snapshot
Health effects of terpenoids
inferred← citeshttps://doi.org/10.1016/b978-0-323-90390-5.00010-4openalex-snapshot
Phytochemicals as potential biopharmaceutical agents
inferred← citeshttps://doi.org/10.1016/b978-0-443-18611-0.00007-3openalex-snapshot
Casbene-derived diterpenoids
inferred← citeshttps://doi.org/10.1016/b978-0-443-33885-4.00028-7openalex-snapshot
Drug development based on natural products of Euphorbia genus
inferred← citeshttps://doi.org/10.1016/j.arabjc.2022.103807openalex-snapshot
Six new tigliane diterpenoids with anti-inflammatory activity from Euphorbia kansuensis
inferred← citeshttps://doi.org/10.1016/j.arabjc.2022.104203openalex-snapshot
Euphorane C, an unusual C17-norabietane diterpenoid from Euphorbia dracunculoides induces cell cycle arrest and apoptosis in human leukemia K562 cells
inferred← citeshttps://doi.org/10.1016/j.bbr.2026.116165openalex-snapshot
Targeting orofacial pain: From pathophysiological mechanisms to Traditional Chinese Medicine approaches
inferred← citeshttps://doi.org/10.1016/j.bioorg.2018.06.025openalex-snapshot
Cytotoxic macrocyclic diterpenoids from Jatropha multifida
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103237openalex-snapshot
NO inhibitory diterpenoids as potential anti-inflammatory agents from Euphorbia antiquorum
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103292openalex-snapshot
Discovery of diverse diterpenoid scaffolds from Euphorbia antiquorum and their activity against RANKL-induced osteoclastogenesis
inferred← citeshttps://doi.org/10.1016/j.bioorg.2019.103546openalex-snapshot
Ingol diterpenoids as P-glycoprotein-dependent multidrug resistance (MDR) reversal agents from Euphorbia marginata
inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.103763openalex-snapshot
Euphoresulanes A–M, structurally diverse jatrophane diterpenoids from Euphorbia esula
inferred← citeshttps://doi.org/10.1016/j.bioorg.2020.104464openalex-snapshot
Macrocyclic diterpenoids from the seeds of Euphorbia peplus with potential activity in inducing lysosomal biogenesis
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.104944openalex-snapshot
Diterpenoids from the seeds of Euphorbia lathyris and their anti-inflammatory activity
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.104989openalex-snapshot
Jatrophane diterpenoids as multidrug resistance modulators from Euphorbia sororia
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105356openalex-snapshot
Bisfischoids A and B, dimeric ent-abietane-type diterpenoids with anti-inflammatory potential from Euphorbia fischeriana Steud.
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105442openalex-snapshot
Diterpenoids from Euphorbia glomerulans with potential reversal activities against P-glycoprotein-mediated multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.bioorg.2021.105534openalex-snapshot
Diterpenoids from Euphorbia helioscopia and their enhancement of NK cell-mediated killing of NSCLC cells
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.105759openalex-snapshot
Cytotoxic diterpenoid dimer containing an intricately caged core from Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106103openalex-snapshot
Tigliane and rhamnofolane glycosides from Euphorbia wallichii prevent oxidative stress-induced neuronal death in PC-12 cells
inferred← citeshttps://doi.org/10.1016/j.bioorg.2022.106329openalex-snapshot
Synthesis, antiproliferative and anti-MDR activities of lathyrane diterpene derivatives based on configuration inversion strategy
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106595openalex-snapshot
Discovery of myrsinane-type Euphorbia diterpene derivatives through a skeleton conversion strategy from lathyrane diterpene for the treatment of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.bioorg.2023.106619openalex-snapshot
Diterpenoids with an unusual tricyclo[10.3.0.02,9]pentadecane skeleton from Pedilanthus tithymaloides as multidrug resistance modulators
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107377openalex-snapshot
Lathyrane and premyrsinane Euphorbia diterpenes against Alzheimer's disease: Bioinspired synthesis, anti-cholinesterase and neuroprotection bioactivity
inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107769openalex-snapshot
Effect of lathyrane-type diterpenoids in neural stem cell physiology: Microbial transformations, molecular docking and dynamics studies
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.108961openalex-snapshot
Tigliane glycosides from Euphorbia tirucalli as multidrug resistance modulators
inferred← citeshttps://doi.org/10.1016/j.bioorg.2025.109241openalex-snapshot
Diversified applications and research progress of plant-derived natural products in PROTAC technology
inferred← citeshttps://doi.org/10.1016/j.biopha.2026.119721openalex-snapshot
Euphol targets key oncogenic processes and promotes chemoprevention in organoid and In Vivo models of colorectal cancers
inferred← citeshttps://doi.org/10.1016/j.bjp.2016.11.002openalex-snapshot
Euphorbia umbellata bark extracts – an in vitro cytotoxic study
inferred← citeshttps://doi.org/10.1016/j.bmc.2017.04.016openalex-snapshot
Lathyrol and epoxylathyrol derivatives: Modulation of Cdr1p and Mdr1p drug-efflux transporters of Candida albicans in Saccharomyces cerevisiae model
inferred← citeshttps://doi.org/10.1016/j.bmc.2023.117366openalex-snapshot
Daphnanes diterpenes from the latex of Hura crepitans L. and their PKCζ-dependent anti-proliferative activity on colorectal cancer cells
inferred← citeshttps://doi.org/10.1016/j.bmc.2025.118516openalex-snapshot
Biomimetic semi-synthesis, structural optimization and anti-HIV activity of naturally scarce eupholathone-, lathyranone- and integerrimine-type Euphorbia diterpenoids
inferred← citeshttps://doi.org/10.1016/j.bmcl.2016.05.035openalex-snapshot
Jatrophane and ingenane-type diterpenoids from Euphorbia kansui inhibit the LPS-induced NO production in RAW 264.7 cells
inferred← citeshttps://doi.org/10.1016/j.bmcl.2017.08.054openalex-snapshot
Synthesis and biological evaluation of the natural product komaroviquinone and related compounds aiming at a potential therapeutic lead compound for high-risk multiple myeloma
inferred← citeshttps://doi.org/10.1016/j.bse.2019.04.006openalex-snapshot
Chemical constituents from Euphorbia stracheyi Boiss
inferred← citeshttps://doi.org/10.1016/j.bse.2020.104016openalex-snapshot
Chemical constituents from Senefelderopsis croizatii Steyerm
inferred← citeshttps://doi.org/10.1016/j.bse.2021.104307openalex-snapshot
Chemical constituents of Euphorbia peplus
inferred← citeshttps://doi.org/10.1016/j.cclet.2022.03.003openalex-snapshot
Octacyclic and decacyclic ent‑abietane dimers with cytotoxic activity from Euphorbia fischeriana steud.
inferred← citeshttps://doi.org/10.1016/j.cclet.2026.113232openalex-snapshot
Eufischeramines A and B: Ingenane-type diterpenoid alkaloids from Euphorbia fischeriana with potent anti-pulmonary fibrosis activity
inferred← citeshttps://doi.org/10.1016/j.chroma.2015.09.092openalex-snapshot
Insights on profiling of phorbol, deoxyphorbol, ingenol and jatrophane diterpene esters by high performance liquid chromatography coupled to multiple stage mass spectrometry
inferred← citeshttps://doi.org/10.1016/j.compbiomed.2023.107007openalex-snapshot
Network pharmacology and molecular docking combined with widely targeted metabolomics to elucidate the potential compounds and targets of Euphorbia helioscopia seeds for the treatment of pulmonary fibrosis
inferred← citeshttps://doi.org/10.1016/j.ejmech.2015.08.057openalex-snapshot
Design, synthesis and biological evaluation of tricyclic diterpene derivatives as novel neuroprotective agents against ischemic brain injury
inferred← citeshttps://doi.org/10.1016/j.ejmech.2016.05.045openalex-snapshot
neo-Clerodane diterpenoids from Scutellaria barbata mediated inhibition of P-glycoprotein in MCF-7/ADR cells
inferred← citeshttps://doi.org/10.1016/j.ejmech.2017.03.008openalex-snapshot
Synthesis of heterocyclic ring-fused tricyclic diterpene analogs as novel inhibitors of RANKL-induced osteoclastogenesis and bone resorption
inferred← citeshttps://doi.org/10.1016/j.ejmech.2018.01.027openalex-snapshot
Jatrophane diterpenoids from Euphorbia sororia as potent modulators against P-glycoprotein-based multidrug resistance
inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.05.005openalex-snapshot
Synthesis and biological evaluation of methylpyrimidine-fused tricyclic diterpene analogs as novel oral anti-late-onset hypogonadism agents
inferred← citeshttps://doi.org/10.1016/j.ejmech.2025.118458openalex-snapshot
Exploring novel aromatase cytochrome P450-binding ligands: Molecular docking and QSAR study of phorbol esters as aromatase inhibitors
inferred← citeshttps://doi.org/10.1016/j.fitote.2015.05.012openalex-snapshot
Cyparissins A and B, jatrophane diterpenes from Euphorbia cyparissias as Pgp inhibitors and cytotoxic agents against ovarian cancer cell lines
inferred← citeshttps://doi.org/10.1016/j.fitote.2015.06.021openalex-snapshot
LC-MS2-Based dereplication of Euphorbia extracts with anti-Chikungunya virus activity
inferred← citeshttps://doi.org/10.1016/j.fitote.2015.11.008openalex-snapshot
6(17)-Epoxylathyrane diterpenes from Euphorbia sogdiana Popov with cytotoxic activity
inferred← citeshttps://doi.org/10.1016/j.fitote.2018.03.009openalex-snapshot
LC-MS guided isolation of diterpenoids from Sapium insigne with α-glucosidase inhibitory activities
inferred← citeshttps://doi.org/10.1016/j.fitote.2019.01.015openalex-snapshot
Lewis acid-mediated skeleton transformation of Euphorbia diterpenes: From lathyrane to euphoractane and myrsinane
inferred← citeshttps://doi.org/10.1016/j.fitote.2019.04.001openalex-snapshot
Further terpenoids from Euphorbia tirucalli
inferred← citeshttps://doi.org/10.1016/j.fitote.2019.104408openalex-snapshot
Sesquiterpenes and diterpenes from Euphorbia thymifolia
inferred← citeshttps://doi.org/10.1016/j.fitote.2020.104583openalex-snapshot
Diterpenes with potential treatment of vitiligo from the aerials parts of Euphorbia antiquorum L
inferred← citeshttps://doi.org/10.1016/j.fitote.2020.104680openalex-snapshot
Transcriptome analysis of the medicinally significant plant Fontainea picrosperma (Euphorbiaceae) reveals conserved biosynthetic pathways
inferred← citeshttps://doi.org/10.1016/j.fitote.2020.104710openalex-snapshot
An unexpected Lewis acid-mediated structural conversion of a Euphorbia Diterpene: From a Lathyrane skeleton to diterpene pseudo-alkaloids
inferred← citeshttps://doi.org/10.1016/j.fitote.2020.104810openalex-snapshot
Daphnane-type diterpenoids from Euphorbia fischeriana Steud and their cytotoxic activities
inferred← citeshttps://doi.org/10.1016/j.fitote.2021.104888openalex-snapshot
Structurally diverse triterpenoids with cytotoxicity from Euphorbia hypericifolia
inferred← citeshttps://doi.org/10.1016/j.fitote.2022.105139openalex-snapshot
Euphzycopias A−I, macrocyclic diterpenes with NLRP3 inflammasome inhibitory activity from Euphorbia helioscopia L.
inferred← citeshttps://doi.org/10.1016/j.fitote.2022.105195openalex-snapshot
An unusual indole-diterpenoid with C-17 norcassane skeleton from Euphorbia fischeriana induces HEL cell cycle arrest and apoptosis
inferred← citeshttps://doi.org/10.1016/j.fitote.2023.105466openalex-snapshot
An overview of the traditional use, phytochemistry, and biological activity of the genus Homalanthus
inferred← citeshttps://doi.org/10.1016/j.fitote.2023.105614openalex-snapshot
Euphopias G − J, macrocyclic diterpenes with anti-zika virus activity from Euphorbia helioscopia L
inferred← citeshttps://doi.org/10.1016/j.fitote.2024.105821openalex-snapshot
Euphzycopins A − D, macrocyclic diterpenoids with potential anti-inflammatory activity from Euphorbia Helioscopia
inferred← citeshttps://doi.org/10.1016/j.fitote.2024.105838openalex-snapshot
Diverse diterpenoids and a triterpenoid from Euphorbia spinidens Bornm. ex Prokh
inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106385openalex-snapshot
Rapid isolation of cytotoxic daphnane diterpenoids from Daphne altaica Pall. using MS-DIAL
inferred← citeshttps://doi.org/10.1016/j.fitote.2025.106525openalex-snapshot
Tigliane and premyrsinane diterpenoids from Euphorbia monostyla and their cytotoxic activity
inferred← citeshttps://doi.org/10.1016/j.fitote.2026.107119openalex-snapshot
New terpenoids from Euphorbia pekinensis with potent and selective anti-hepatocellular carcinoma activity
inferred← citeshttps://doi.org/10.1016/j.gresc.2026.05.006openalex-snapshot
Recent advances in the total synthesis of highly strained tetracyclic diterpenoids from Euphorbiaceae: Pepluanols and Euphorikanin A
inferred← citeshttps://doi.org/10.1016/j.heliyon.2023.e13691openalex-snapshot
Euphejolkinolide A, a new ent-abietane lactone from Euphorbia peplus L. with promising biological activity in activating the autophagy-lysosomal pathway
inferred← citeshttps://doi.org/10.1016/j.indcrop.2022.115096openalex-snapshot
Integrating metabolomics and transcriptomics to unveil the spatiotemporal distribution of macrocyclic diterpenoids and candidate genes involved in ingenol biosynthesis in the medicinal plant Euphorbia lathyris L.
inferred← citeshttps://doi.org/10.1016/j.jcoa.2026.100312openalex-snapshot
Polyphenolic profiling of Euphorbia cardiophylla, an endemic Turkish species, using Liquid chromatography-High resolution Orbitrap mass spectrometry and investigating its biological activity
inferred← citeshttps://doi.org/10.1016/j.jep.2015.10.025openalex-snapshot
Global medicinal uses of Euphorbia L. (Euphorbiaceae)
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112557openalex-snapshot
Effect of the vinegar-process on chemical compositions and biological activities of Euphorbia kansui: A review
inferred← citeshttps://doi.org/10.1016/j.jep.2020.112878openalex-snapshot
Topical medicines for wound healing: A systematic review of Unani literature with recent advances
inferred← citeshttps://doi.org/10.1016/j.jep.2021.114581openalex-snapshot
Jolkinolide B inhibits proliferation or migration and promotes apoptosis of MCF-7 or BT-474 breast cancer cells by downregulating the PI3K-Akt pathway
inferred← citeshttps://doi.org/10.1016/j.jep.2022.115574openalex-snapshot
Phytochemical and pharmacological review of diterpenoids from the genus Euphorbia Linn (2012–2021)
inferred← citeshttps://doi.org/10.1016/j.jep.2026.121772openalex-snapshot
Traditional Herbal Medicine Euphorbia milii Des Moul: Research progress in chemical constituents and pharmacological activities
inferred← citeshttps://doi.org/10.1016/j.jpba.2018.07.059openalex-snapshot
Phytochemical profile of Euphorbia peplus L. collected in Central Italy and NMR semi-quantitative analysis of the diterpenoid fraction
inferred← citeshttps://doi.org/10.1016/j.jsps.2017.08.001openalex-snapshot
Quantitative and qualitative analysis for standardization of Euphorbia cuneata Vahl
inferred← citeshttps://doi.org/10.1016/j.molcatb.2017.02.008openalex-snapshot
Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis
inferred← citeshttps://doi.org/10.1016/j.molstruc.2021.131237openalex-snapshot
Comprehensive investigation of structural properties (X-ray diffraction, IR, Hirshfeld, MEP and FMOs) and in silico screening of potential biological activity of Euphorbia factor L1
inferred← citeshttps://doi.org/10.1016/j.nexres.2026.102321openalex-snapshot
Euphorbia royleana Boiss., as a source of bioactive compounds: Traditional uses and pharmacological evidence
inferred← citeshttps://doi.org/10.1016/j.phymed.2016.05.007openalex-snapshot
Jatrophane diterpenes and cancer multidrug resistance – ABCB1 efflux modulation and selective cell death induction
inferred← citeshttps://doi.org/10.1016/j.phytochem.2016.12.021openalex-snapshot
Chemical profile and defensive function of the latex of Euphorbia peplus
inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.10.006openalex-snapshot
Diterpenes from the stem bark of Euphorbia neriifolia and their in vitro anti-HIV activity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.10.012openalex-snapshot
Highly oxygenated and structurally diverse diterpenoids from Euphorbia helioscopia
inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.01.016openalex-snapshot
Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis
inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.12.003openalex-snapshot
Cytochrome P450 enzymes: A driving force of plant diterpene diversity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2019.112064openalex-snapshot
Euphonoids A−G, cytotoxic diterpenoids from Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112360openalex-snapshot
Anti-HIV tigliane diterpenoids from Reutealis trisperma
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112395openalex-snapshot
Diterpenoids from Euphorbia royleana reverse P-glycoprotein-mediated multidrug resistance in cancer cells
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112437openalex-snapshot
Antiproliferative diterpenoids and acetophenone glycoside from the roots of Euphorbia fischeriana
inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112523openalex-snapshot
Diterpenoids from the aerial parts of Euphorbia antiquorum and their efficacy on nitric oxide inhibition
inferred← citeshttps://doi.org/10.1016/j.phytochem.2021.112846openalex-snapshot
Diterpenoids from the genus Euphorbia: Structure and biological activity (2013–2019)
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113344openalex-snapshot
Ingol, ent-atisane, and stachane-type diterpenoids from Euphorbia deightonii with multidrug resistance reversing activity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113382openalex-snapshot
Diterpene glycosides, acetophenone glycosides and tannins from polar extracts of the root of Euphorbia fischeriana with cytotoxicity and antibacterial activities
inferred← citeshttps://doi.org/10.1016/j.phytochem.2022.113420openalex-snapshot
Jatrophane diterpenoids with cytotoxic activity from the whole plant of Euphorbia heliosocpia L
inferred← citeshttps://doi.org/10.1016/j.phytochem.2023.113682openalex-snapshot
Anti-inflammatory lanostane triterpenoids with rearranged spirobi[indene] scaffold and their biogenetically related analogues from Euphorbia maculata
inferred← citeshttps://doi.org/10.1016/j.phytochem.2023.113745openalex-snapshot
Diterpenoids from Euphorbia lactea and their anti-HIV-1 activity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.113996openalex-snapshot
Ent-atisane diterpenoids from Euphorbia wallichii and their anti-influenza A virus activity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114043openalex-snapshot
Structurally intriguing diterpenoids from Euphorbia wallichii Hook. f. with potential antioxidant activity
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114193openalex-snapshot
Targeted discovery of unusual diterpenoids with anti-fungal activity from the root of Euphorbia lathyris
inferred← citeshttps://doi.org/10.1016/j.phytochem.2024.114256openalex-snapshot
Lathyrane and ent-isopimarane diterpenoids from Euphorbia wallichii and target prediction of active ingredient
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114418openalex-snapshot
Undescribed diterpenes from Euphorbia mauritanica L. as modulators of the breast cancer resistance: Mechanistic and in silico studies
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114575openalex-snapshot
Efficient NMR spectroscopy approach for the determination of the relative configuration of Δ5,6Δ11,12-jatrophane diterpenes and their chemotherapy sensitization activities
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114657openalex-snapshot
Euphebranes A−G: higher diterpenoids from the radix of Euphorbia ebracteolata
inferred← citeshttps://doi.org/10.1016/j.phytochem.2025.114712openalex-snapshot
Euphorbia diterpenoids from Euphorbia peplus possessing anti-Alzheimer's activity via targeting PPARγ and upregulating the level of ABCA1
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