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Adiponectin-Secretion-Promoting Phenylethylchromones from the Agarwood of Aquilaria malaccensis

https://doi.org/10.1021/acs.jnatprod.8b00635

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/hlca.201100442openalex-snapshot

Two New 2‐(2‐Phenylethyl)chromen‐4‐ones from Aquilaria sinensis ( Lour. ) Gilg

inferredcites →https://doi.org/10.1002/hlca.201200069openalex-snapshot

Eight New 2‐(2‐Phenylethyl)chromone (=2‐(2‐Phenylethyl)‐4 H ‐1‐benzopyran‐4‐one) Derivatives from Aquilaria malaccensis Agarwood

inferredcites →https://doi.org/10.1016/j.bbagen.2017.05.008openalex-snapshot

X-ray crystal structure of rivoglitazone bound to PPARγ and PPAR subtype selectivity of TZDs

inferredcites →https://doi.org/10.1016/j.bcp.2009.03.008openalex-snapshot

Interleukin-17A inhibits adipocyte differentiation in human mesenchymal stem cells and regulates pro-inflammatory responses in adipocytes

inferredcites →https://doi.org/10.1016/j.bcp.2011.12.010openalex-snapshot

Interleukin-17A increases leptin production in human bone marrow mesenchymal stem cells

inferredcites →https://doi.org/10.1016/j.bmc.2018.01.019openalex-snapshot

2-Formyl-komarovicine promotes adiponectin production in human mesenchymal stem cells through PPARγ partial agonism

inferredcites →https://doi.org/10.1016/j.bmcl.2014.03.034openalex-snapshot

Kojyl cinnamate ester derivatives promote adiponectin production during adipogenesis in human adipose tissue-derived mesenchymal stem cells

inferredcites →https://doi.org/10.1016/s0223-5234(01)01218-1openalex-snapshot

Synthesis and biological evaluation of some novel 4H-benzopyran-4-one derivatives as nonsteroidal antiestrogens

inferredcites →https://doi.org/10.1021/acs.jmedchem.7b00805openalex-snapshot

Polypharmacology ofN6-(3-Iodobenzyl)adenosine-5′-N-methyluronamide (IB-MECA) and Related A3Adenosine Receptor Ligands: Peroxisome Proliferator Activated Receptor (PPAR) γ Partial Agonist and PPARδ Antagonist Activity Suggests Their Antidiabetic Potential

inferredcites →https://doi.org/10.1021/acs.jnatprod.7b00462openalex-snapshot

Aquilanols A and B, Macrocyclic Humulene-Type Sesquiterpenoids from the Agarwood of Aquilaria malaccensis

inferredcites →https://doi.org/10.1021/cr400265zopenalex-snapshot

Chromone: A Valid Scaffold in Medicinal Chemistry

inferredcites →https://doi.org/10.1021/jm501155fopenalex-snapshot

Peroxisome Proliferator-Activated Receptor γ (PPARγ) and Ligand Choreography: Newcomers Take the Stage

inferredcites →https://doi.org/10.1021/jm800733hopenalex-snapshot

Crystal Structure of the Peroxisome Proliferator-Activated Receptor γ (PPARγ) Ligand Binding Domain Complexed with a Novel Partial Agonist: A New Region of the Hydrophobic Pocket Could Be Exploited for Drug Design

inferredcites →https://doi.org/10.1021/np0503808openalex-snapshot

Neuroprotective 2-(2-Phenylethyl)chromones of Imperata cylindrica

inferredcites →https://doi.org/10.1021/np50017a010openalex-snapshot

Plant Anticancer Agents. XIX. Constituents of Aquilaria malaccensis

inferredcites →https://doi.org/10.1038/25931openalex-snapshot

Ligand binding and co-activator assembly of the peroxisome proliferator-activated receptor-γ

inferredcites →https://doi.org/10.1038/90984openalex-snapshot

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

inferredcites →https://doi.org/10.1038/90992openalex-snapshot

The adipocyte-secreted protein Acrp30 enhances hepatic insulin action

inferredcites →https://doi.org/10.1038/ncomms4571openalex-snapshot

An alternate binding site for PPARγ ligands

inferredcites →https://doi.org/10.1055/s-0033-1350647openalex-snapshot

2-(2-Phenylethyl)chromone Derivatives in Chinese Agarwood “Qi-Nan” from Aquilaria sinensis

inferredcites →https://doi.org/10.1161/01.atv.0000099786.99623.efopenalex-snapshot

Adiponectin and Metabolic Syndrome

inferredcites →https://doi.org/10.1161/01.atv.0000256469.06782.d5openalex-snapshot

Effects of Peroxisome Proliferator-Activated Receptor Ligands, Bezafibrate and Fenofibrate, on Adiponectin Level

inferredcites →https://doi.org/10.1172/jci17797openalex-snapshot

The fat-derived hormone adiponectin alleviates alcoholic and nonalcoholic fatty liver diseases in mice

inferredcites →https://doi.org/10.1172/jci29126openalex-snapshot

Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome

inferredcites →https://doi.org/10.1210/er.2011-1015openalex-snapshot

The Role of Adiponectin in Cancer: A Review of Current Evidence

inferredcites →https://doi.org/10.1248/cpb.30.3791openalex-snapshot

Studies on the agarwood (Jinko). I. Structures of 2-(2-phenylethyl) chromone derivatives.

inferredcites →https://doi.org/10.1248/cpb.33.5088openalex-snapshot

A new chromone from agarwood and pyrolysis products of chromone derivatives.

inferredcites →https://doi.org/10.1248/cpb.51.560openalex-snapshot

Four New 2-(2-Phenylethyl)chromone Derivatives from Withered Wood of Aquilaria sinensis

inferredcites →https://doi.org/10.2337/db09-1338openalex-snapshot

Macrophage Adiponectin Expression Improves Insulin Sensitivity and Protects Against Inflammation and Atherosclerosis

inferredcites →https://doi.org/10.2337/diabetes.52.7.1655openalex-snapshot

Induction of Adiponectin, a Fat-Derived Antidiabetic and Antiatherogenic Factor, by Nuclear Receptors

inferredcites →https://doi.org/10.3724/sp.j.1009.2013.00077openalex-snapshot

Two new chromones and a new flavone glycoside from Imperata cylindrica

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2020.112630zenodo-depositor-declared

Sesquiterpene derivatives from the agarwood of Aquilaria malaccensis and their anti-inflammatory effects on NO production of macrophage RAW 264.7 cells

inferred← citeshttps://doi.org/10.1002/cbdv.202200490openalex-snapshot

Chemical and Bioactivity Diversity of 2‐(2‐Phenylethyl)chromones in Agarwood: A Review

inferred← citeshttps://doi.org/10.1007/s00204-019-02462-1openalex-snapshot

A long-wave UVA filter avobenzone induces obesogenic phenotypes in normal human epidermal keratinocytes and mesenchymal stem cells

inferred← citeshttps://doi.org/10.1007/s13659-021-00313-0openalex-snapshot

Sesquiterpenoids and 2-(2-Phenylethyl)chromone Derivatives from the Resinous Heartwood of Aquilaria sinensis

inferred← citeshttps://doi.org/10.1016/j.bioorg.2024.107890openalex-snapshot

Butanolides and clerodane diterpenes from the twigs of Casearia grewiifolia and their effects on adiponectin secretion

inferred← citeshttps://doi.org/10.1016/j.bmc.2019.05.028openalex-snapshot

2-Phenyl-8-(1-phenylallyl)-chromenone compounds have a pan-PPAR modulator pharmacophore

inferred← citeshttps://doi.org/10.1016/j.ejmech.2019.111969openalex-snapshot

Novel linked butanolide dimer compounds increase adiponectin production during adipogenesis in human mesenchymal stem cells through peroxisome proliferator-activated receptor γ modulation

inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114397openalex-snapshot

Occurrence, synthesis and biological activity of 2-(2-phenyethyl)chromones

inferred← citeshttps://doi.org/10.1016/j.ejmech.2022.114927openalex-snapshot

Discovery of PPARγ and glucocorticoid receptor dual agonists to promote the adiponectin and leptin biosynthesis in human bone marrow mesenchymal stem cells

inferred← citeshttps://doi.org/10.1016/j.ica.2025.122792openalex-snapshot

Nickel(II) metallates induced intrinsic apoptotic pathway-mediated cell death in lung and breast cancer cells

inferred← citeshttps://doi.org/10.1016/j.indcrop.2021.114129openalex-snapshot

The formation and quality evaluation of agarwood induced by the fungi in Aquilaria sinensis

inferred← citeshttps://doi.org/10.1016/j.indcrop.2026.122698openalex-snapshot

Bioactivity and in silico insights into 2-(2-phenylethyl)-4H-chromen-4-one and sesquiterpenoid constituents from agarwood (Aquilaria sinensis) as anti-inflammatory agents

inferred← citeshttps://doi.org/10.1016/j.nexres.2025.101117openalex-snapshot

A critical review on agarwood: biosynthesis, therapeutic potential, trade, and conservation challenges

inferred← citeshttps://doi.org/10.1016/j.sajb.2022.10.020openalex-snapshot

An insight into the immunomodulatory potential of wood oil of Aquilaria malaccensis Lam. with an emphasis into related phytomedicine, biomarkers, pharmacology, and toxicity

inferred← citeshttps://doi.org/10.1016/j.yexcr.2026.114947openalex-snapshot

Agarotetrol attenuates spinal cord injury by targeting PPARγ to modulate microglial activation

inferred← citeshttps://doi.org/10.1021/acs.jcim.3c00033openalex-snapshot

Computational Prediction of the Phenotypic Effect of Flavonoids on Adiponectin Biosynthesis

inferred← citeshttps://doi.org/10.1021/acs.jmedchem.0c01874openalex-snapshot

Discovery and Structure–Activity Relationships of Novel Template, Truncated 1′-Homologated Adenosine Derivatives as Pure Dual PPARγ/δ Modulators

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.1c01102openalex-snapshot

Adiponectin-Secretion-Promoting Cyclic Peptide–Polyketide Hybrids from a Halophyte-Associated Fungus, Colletotrichum gloeosporioides JS0417

inferred← citeshttps://doi.org/10.1021/acs.jnatprod.2c00844openalex-snapshot

Alkaloids and Coumarins with Adiponectin-Secretion-Promoting Activities from the Leaves of Orixa japonica

inferred← citeshttps://doi.org/10.1021/acsabm.3c00200openalex-snapshot

Multifaceted Chiral Probe 2,3-Dihydro-4-hydroxy-chromene Schiff Base in Detecting Cu2+ Ions, l -Histidine, and Indazole: Spectroscopic Investigation and Confocal and Live Cell Imaging

inferred← citeshttps://doi.org/10.1039/d0np00042fopenalex-snapshot

Natural products in agarwood and Aquilaria plants: chemistry, biological activities and biosynthesis

inferred← citeshttps://doi.org/10.1080/21501203.2025.2602352openalex-snapshot

Metabolites associated with endophytic fungi in agarwood: fungal compounds and host metabolites triggered by fungi

inferred← citeshttps://doi.org/10.1093/jimb/kuaf025openalex-snapshot

Towards sustainable agarwood production: integrating microbial interactions, anatomical changes, and metabolite biosynthesis

inferred← citeshttps://doi.org/10.26512/abyayala.v1i3.7124openalex-snapshot

El continuum de las violencias en un contexto del noreste de México. Notas desde una experiencia de investigación social contemporánea

inferred← citeshttps://doi.org/10.26538/tjnpr/v9i8.2openalex-snapshot

Review of Potential Pharmacological Activities of Agarwood Plants (Aquilaria Sp.) as Herbal Medicine and Development as Potential Herbal Preparations

inferred← citeshttps://doi.org/10.3389/fphar.2024.1468393openalex-snapshot

Pharmacology and therapeutic potential of agarwood and agarwood tree leaves in periodontitis

inferred← citeshttps://doi.org/10.3390/biom10020275openalex-snapshot

Cyclin-Dependent Kinase 5 Inhibitor Butyrolactone I Elicits a Partial Agonist Activity of Peroxisome Proliferator-Activated Receptor γ

inferred← citeshttps://doi.org/10.3390/molecules24101990openalex-snapshot

Chemical Profiles of Cultivated Agarwood Induced by Different Techniques

inferred← citeshttps://doi.org/10.3390/molecules28041667openalex-snapshot

Comprehensive Comparisons between Grafted Kynam Agarwood and Normal Agarwood on Traits, Composition, and In Vitro Activation of AMPK

inferred← citeshttps://doi.org/10.3390/ph17111548openalex-snapshot

The Potential Therapeutic Use of Agarwood for Diabetes: A Scoping Review

inferred← citeshttps://doi.org/10.3390/plants14071012openalex-snapshot

Biosynthesis and Its Regulatory Mechanisms of 2-(2-Phenylethyl)chromones in Agarwood

inferred← citeshttps://doi.org/10.4062/biomolther.2025.005openalex-snapshot

Dimethyl Sulfoxide Shifts Human Mesenchymal Stem Cell Differentiation toward Adipogenesis over Osteogenesis

inferred← citeshttps://doi.org/10.4103/cmac.cmac_43_21openalex-snapshot

Medicinal uses of agarwood

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