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Biodegradable Metal–Organic-Frameworks-Mediated Protein Delivery Enables Intracellular Cascade Biocatalysis and Pyroptosis In Vivo
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What this work says
Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1002/adma.201902791openalex-snapshot
Rational Design of Nanocarriers for Intracellular Protein Delivery
inferredcites →https://doi.org/10.1002/adma.201907267openalex-snapshot
Metal–Organic Framework Nanoparticles Induce Pyroptosis in Cells Controlled by the Extracellular pH
inferredcites →https://doi.org/10.1002/adma.202006892openalex-snapshot
Nanocatalytic Theranostics with Glutathione Depletion and Enhanced Reactive Oxygen Species Generation for Efficient Cancer Therapy
inferredcites →https://doi.org/10.1002/adma.202104355openalex-snapshot
Dynamic Polymer Amphiphiles for Efficient Intracellular and In Vivo Protein Delivery
inferredcites →https://doi.org/10.1002/adma.202108174openalex-snapshot
Engineering Multienzyme‐Mimicking Covalent Organic Frameworks as Pyroptosis Inducers for Boosting Antitumor Immunity
inferredcites →https://doi.org/10.1002/anie.201916474openalex-snapshot
“Armor‐Plating” Enzymes with Metal–Organic Frameworks (MOFs)
inferredcites →https://doi.org/10.1002/anie.202004008openalex-snapshot
Hypoxia‐Induced Pro‐Protein Therapy Assisted by a Self‐Catalyzed Nanozymogen
inferredcites →https://doi.org/10.1002/anie.202004180openalex-snapshot
Self‐Boosting Catalytic Nanoreactors Integrated with Triggerable Crosslinking Membrane Networks for Initiation of Immunogenic Cell Death by Pyroptosis
inferredcites →https://doi.org/10.1002/anie.202010281openalex-snapshot
Cell Death Mediated by the Pyroptosis Pathway with the Aid of Nanotechnology: Prospects for Cancer Therapy
inferredcites →https://doi.org/10.1002/anie.202013904openalex-snapshot
Hierarchical Self‐assembly of Discrete Metal–Organic Cages into Supramolecular Nanoparticles for Intracellular Protein Delivery
inferredcites →https://doi.org/10.1002/anie.202016399openalex-snapshot
Activation of Pyroptosis by Membrane‐Anchoring AIE Photosensitizer Design: New Prospect for Photodynamic Cancer Cell Ablation
inferredcites →https://doi.org/10.1002/anie.202102574openalex-snapshot
Antitumor Agents Based on Metal–Organic Frameworks
inferredcites →https://doi.org/10.1002/anie.202107036openalex-snapshot
Hypoxia‐Responsive Gene Editing to Reduce Tumor Thermal Tolerance for Mild‐Photothermal Therapy
inferredcites →https://doi.org/10.1002/anie.202115800openalex-snapshot
A Carbonic Anhydrase IX (CAIX)‐Anchored Rhenium(I) Photosensitizer Evokes Pyroptosis for Enhanced Anti‐Tumor Immunity
inferredcites →https://doi.org/10.1002/smll.202006599openalex-snapshot
A Virus‐Spike Tumor‐Activatable Pyroptotic Agent
inferredcites →https://doi.org/10.1016/j.cell.2021.06.028openalex-snapshot
Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway
inferredcites →https://doi.org/10.1016/j.jcis.2020.12.028openalex-snapshot
Cu-MOF chemodynamic nanoplatform via modulating glutathione and H2O2 in tumor microenvironment for amplified cancer therapy
inferredcites →https://doi.org/10.1021/acs.accounts.8b00493openalex-snapshot
Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing
inferredcites →https://doi.org/10.1021/acs.chemrev.0c01029openalex-snapshot
Metal–Organic Framework-Based Enzyme Biocomposites
inferredcites →https://doi.org/10.1021/acs.nanolett.1c02790openalex-snapshot
Biodegradable Upconversion Nanoparticles Induce Pyroptosis for Cancer Immunotherapy
inferredcites →https://doi.org/10.1021/acsami.0c01539openalex-snapshot
Fusiform-Like Copper(II)-Based Metal–Organic Framework through Relief Hypoxia and GSH-Depletion Co-Enhanced Starvation and Chemodynamic Synergetic Cancer Therapy
inferredcites →https://doi.org/10.1021/acsami.1c00829openalex-snapshot
Correlation between Protonation of Tailor-Made Polypiperazines and Endosomal Escape for Cytosolic Protein Delivery
inferredcites →https://doi.org/10.1021/acsami.1c10816openalex-snapshot
Phosphate-Degradable Nanoparticles Based on Metal–Organic Frameworks for Chemo-Starvation-Chemodynamic Synergistic Antitumor Therapy
inferredcites →https://doi.org/10.1021/acsami.1c12611openalex-snapshot
Tumor Microenvironment-Activated Theranostics Nanozymes for Fluorescence Imaging and Enhanced Chemo-Chemodynamic Therapy of Tumors
inferredcites →https://doi.org/10.1021/acsami.2c00552openalex-snapshot
Enhanced Cancer Starvation Therapy Enabled by an Autophagy Inhibitors-Encapsulated Biomimetic ZIF-8 Nanodrug: Disrupting and Harnessing Dual Pro-Survival Autophagic Responses
inferredcites →https://doi.org/10.1021/es0617800openalex-snapshot
Methylene Blue Dye Test for Rapid Qualitative Detection of Hydroxyl Radicals Formed in a Fenton's Reaction Aqueous Solution
inferredcites →https://doi.org/10.1021/jacs.0c09482openalex-snapshot
Na2S2O8 Nanoparticles Trigger Antitumor Immunotherapy through Reactive Oxygen Species Storm and Surge of Tumor Osmolarity
inferredcites →https://doi.org/10.1021/jacs.1c00258openalex-snapshot
Regulation of Proteins to the Cytosol Using Delivery Systems with Engineered Polymer Architecture
inferredcites →https://doi.org/10.1021/jacs.6b03673openalex-snapshot
Encapsulation of a Nerve Agent Detoxifying Enzyme by a Mesoporous Zirconium Metal–Organic Framework Engenders Thermal and Long-Term Stability
inferredcites →https://doi.org/10.1021/jacs.8b04457openalex-snapshot
Biomineralized Metal–Organic Framework Nanoparticles Enable Intracellular Delivery and Endo-Lysosomal Release of Native Active Proteins
inferredcites →https://doi.org/10.1021/jacs.8b08714openalex-snapshot
Self-Assembled Copper–Amino Acid Nanoparticles for in Situ Glutathione “AND” H2O2 Sequentially Triggered Chemodynamic Therapy
inferredcites →https://doi.org/10.1021/jacs.8b11996openalex-snapshot
Nanoscale ATP-Responsive Zeolitic Imidazole Framework-90 as a General Platform for Cytosolic Protein Delivery and Genome Editing
inferredcites →https://doi.org/10.1021/jacs.9b03457openalex-snapshot
Synthesis of Copper Peroxide Nanodots for H 2 O 2 Self-Supplying Chemodynamic Therapy
inferredcites →https://doi.org/10.1021/jacs.9b08669openalex-snapshot
Enzyme-Instructed Activation of Pro-protein Therapeutics In Vivo
inferredcites →https://doi.org/10.1021/jacs.9b11371openalex-snapshot
Direct Observation of Amorphous Precursor Phases in the Nucleation of Protein–Metal–Organic Frameworks
inferredcites →https://doi.org/10.1021/jacs.9b11638openalex-snapshot
Cell-Type-Specific CRISPR/Cas9 Delivery by Biomimetic Metal Organic Frameworks
inferredcites →https://doi.org/10.1038/nature15514openalex-snapshot
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
inferredcites →https://doi.org/10.1038/nature18629openalex-snapshot
Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
inferredcites →https://doi.org/10.1038/nature22393openalex-snapshot
Chemotherapy drugs induce pyroptosis through caspase-3 cleavage of a gasdermin
inferredcites →https://doi.org/10.1038/ncomms6979openalex-snapshot
Stable metal-organic frameworks containing single-molecule traps for enzyme encapsulation
inferredcites →https://doi.org/10.1038/ncomms8240openalex-snapshot
Biomimetic mineralization of metal-organic frameworks as protective coatings for biomacromolecules
inferredcites →https://doi.org/10.1038/nprot.2006.378openalex-snapshot
Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
inferredcites →https://doi.org/10.1038/s41467-017-00424-8openalex-snapshot
Tumor-selective catalytic nanomedicine by nanocatalyst delivery
inferredcites →https://doi.org/10.1038/s41586-020-2079-1openalex-snapshot
A bioorthogonal system reveals antitumour immune function of pyroptosis
inferredcites →https://doi.org/10.1038/s41929-018-0117-2openalex-snapshot
Biocatalytic cascades driven by enzymes encapsulated in metal–organic framework nanoparticles
inferredcites →https://doi.org/10.1039/c0cs00227eopenalex-snapshot
Tailoring nanocarriers for intracellular protein delivery
inferredcites →https://doi.org/10.1039/c7cs00058hopenalex-snapshot
Enzyme–MOF (metal–organic framework) composites
inferredcites →https://doi.org/10.1039/d0cs00178copenalex-snapshot
Multifunctional metal–organic framework heterostructures for enhanced cancer therapy
inferredcites →https://doi.org/10.1039/d0cs01030hopenalex-snapshot
Stimuli-responsive metal–organic framework nanoparticles for controlled drug delivery and medical applications
inferredcites →https://doi.org/10.1073/pnas.0702176104openalex-snapshot
An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by β-lapachone
inferredcites →https://doi.org/10.1126/science.1230444openalex-snapshot
The Chemistry and Applications of Metal-Organic Frameworks
inferredcites →https://doi.org/10.1126/science.aar7607openalex-snapshot
ESCRT-dependent membrane repair negatively regulates pyroptosis downstream of GSDMD activation
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
inferred← citeshttps://doi.org/10.1002/adfm.202311362openalex-snapshot
Biomaterials Elicit Pyroptosis Enhancing Cancer Immunotherapy
inferred← citeshttps://doi.org/10.1002/smll.202402812openalex-snapshot
Biomineralized ZIF‐8 Encapsulating SOD from Hydrogenobacter Thermophilus: Maintaining Activity in the Intestine and Alleviating Intestinal Oxidative Stress
inferred← citeshttps://doi.org/10.1002/smll.74654openalex-snapshot
NIR‐II Type I AIE Photosensitiser‐Functionalized MOF‐Cu Nanoplatform Promotes Ferroptosis and Cuproptosis for Antitumor Therapy
inferred← citeshttps://doi.org/10.1007/s10565-025-10104-9openalex-snapshot
Distinct mechanisms of cell in breast cancer and their clinical implication
inferred← citeshttps://doi.org/10.1016/j.actbio.2025.01.014openalex-snapshot
Copper-Based biomaterials for anti-tumor therapy: Recent advances and perspectives
inferred← citeshttps://doi.org/10.1016/j.ajps.2024.100948openalex-snapshot
Recent advances in copper homeostasis-involved tumor theranostics
inferred← citeshttps://doi.org/10.1016/j.apsb.2024.11.011openalex-snapshot
Nanomaterials evoke pyroptosis boosting cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.asems.2024.100092openalex-snapshot
Recent progress in pyroptosis probes and inducers
inferred← citeshttps://doi.org/10.1016/j.bioactmat.2023.10.027openalex-snapshot
Engineering materials for pyroptosis induction in cancer treatment
inferred← citeshttps://doi.org/10.1016/j.cej.2025.163961openalex-snapshot
A cerium-based ferroptosis/PANoptosis nano-inducer for photothermal-enhanced combination therapy of breast cancer
inferred← citeshttps://doi.org/10.1016/j.jconrel.2024.05.014openalex-snapshot
Boarding pyroptosis onto nanotechnology for cancer therapy
inferred← citeshttps://doi.org/10.1016/j.matdes.2024.112731openalex-snapshot
Engineering metal-organic framework nanoparticles trigger pyroptosis to boost colon cancer immunotherapy
inferred← citeshttps://doi.org/10.1016/j.matt.2024.101948openalex-snapshot
Efficient oral insulin delivery with sustained release by folate-conjugated metal-organic framework nanoparticles
inferred← citeshttps://doi.org/10.1016/j.mtbio.2026.103111openalex-snapshot
Metal-organic framework nanoparticles induced non-apoptotic cell death: Construction, mechanisms, and cancer therapy
inferred← citeshttps://doi.org/10.1016/j.pmatsci.2025.101526openalex-snapshot
Bridging biodegradable metals and biodegradable polymers: A comprehensive review of biodegradable metal–organic frameworks for biomedical application
inferred← citeshttps://doi.org/10.1021/acsami.3c13162openalex-snapshot
Targeting Lysosome for Enhanced Cancer Photodynamic/Photothermal Therapy in a “One Stone Two Birds” Pattern
inferred← citeshttps://doi.org/10.1021/acsanm.4c03041openalex-snapshot
Bicatalytic Cupric Metal–Organic Framework Nanosheets for Self-Cascade Conversion of Methyl Parathion to 4-Aminophenol
inferred← citeshttps://doi.org/10.1021/acsanm.6c01491openalex-snapshot
Review of Copper-Based Nanozymes for Remodeling the Tumor Immune Microenvironment
inferred← citeshttps://doi.org/10.1038/s43246-026-01163-4openalex-snapshot
Delivering biomedicines with stimuli‑responsive biomaterials
inferred← citeshttps://doi.org/10.1039/d4cc02084gopenalex-snapshot
Metal–organic framework (MOF)-based materials for pyroptosis-mediated cancer therapy
inferred← citeshttps://doi.org/10.1039/d4nr03898copenalex-snapshot
Metal–organic framework microneedles for precision transdermal drug delivery: design strategy and therapeutic potential
inferred← citeshttps://doi.org/10.1039/d4qi02555eopenalex-snapshot
MOF nanozymes: active sites and sensing applications
inferred← citeshttps://doi.org/10.1111/raq.12963openalex-snapshot
Copper Homeostasis and Its Impact on Innate Immunity in Crustaceans
inferred← citeshttps://doi.org/10.1186/s12951-025-03220-5openalex-snapshot
Copper-based metal–organic frameworks for antitumor application
inferred← citeshttps://doi.org/10.12677/acm.2023.1371517openalex-snapshot
Advances in the Treatment of Tumor by Glucose Oxidase Nanomaterials
inferred← citeshttps://doi.org/10.3390/catal13020250openalex-snapshot
Role and Application of Biocatalysts in Cancer Drug Discovery
inferred← citeshttps://doi.org/10.3390/jfb14060301openalex-snapshot
Functional L-Arginine Derivative as an Efficient Vector for Intracellular Protein Delivery for Potential Cancer Therapy
inferred← citeshttps://doi.org/10.3390/nano14070648openalex-snapshot
Advances in Nanodynamic Therapy for Cancer Treatment
inferred← citeshttps://doi.org/10.3390/pharmaceutics15092293openalex-snapshot
Recent Progress of Copper-Based Nanomaterials in Tumor-Targeted Photothermal Therapy/Photodynamic Therapy
inferred← citeshttps://doi.org/10.34133/bmr.0327openalex-snapshot
Surface Engineering of MXenes for Biomedical Uses: Functionalization Strategies and Application Trends
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