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Psychedelics, but Not Ketamine, Produce Persistent Antidepressant-like Effects in a Rodent Experimental System for the Study of Depression
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Outgoing claims: the papers this work cites, builds on, or argues with.
inferredcites →https://doi.org/10.1001/archgenpsychiatry.2010.116openalex-snapshot
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-Stage Cancer
inferredcites →https://doi.org/10.1001/jamapsychiatry.2015.2235openalex-snapshot
Efficacy of Bright Light Treatment, Fluoxetine, and the Combination in Patients With Nonseasonal Major Depressive Disorder
inferredcites →https://doi.org/10.1002/cpt.557openalex-snapshot
Psychedelics as Medicines: An Emerging New Paradigm
inferredcites →https://doi.org/10.1002/syn.21940openalex-snapshot
Gene expression related to serotonergic and glutamatergic neurotransmission is altered in the flinders sensitive line rat model of depression: Effect of ketamine
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Structure–activity relationships of serotonin 5‐HT2Aagonists
inferredcites →https://doi.org/10.1007/978-1-61779-458-2_7openalex-snapshot
Modeling Depression in Animal Models
inferredcites →https://doi.org/10.1007/bf02699783openalex-snapshot
Effect of stress on the behavior and 5-HT system in Sprague-Dawley and Wistar Kyoto rat strains
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Psilocybin with psychological support for treatment-resistant depression: six-month follow-up
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The STAR*D project results: A comprehensive review of findings
inferredcites →https://doi.org/10.1007/s11920-007-0063-1openalex-snapshot
The role of glutamate in mood disorders: Results from the ketamine in major depression study and the presumed cellular mechanism underlying its antidepressant effects
inferredcites →https://doi.org/10.1016/0031-9384(93)90345-gopenalex-snapshot
Sex differences and stress response of WKY rats
inferredcites →https://doi.org/10.1016/0091-3057(77)90180-0openalex-snapshot
Psilocybin: Biphasic dose-response effects on the acoustic startle reflex in the rat
inferredcites →https://doi.org/10.1016/j.bbr.2005.12.001openalex-snapshot
Factor analysis of Forced Swimming test, Sucrose Preference test and Open Field test on enriched, social and isolated reared rats
inferredcites →https://doi.org/10.1016/j.bbr.2009.05.036openalex-snapshot
Wistar–Kyoto rats as an animal model of anxiety vulnerability: Support for a hypervigilance hypothesis
inferredcites →https://doi.org/10.1016/j.bbr.2012.10.049openalex-snapshot
Antidepressant-like effects of curcumin in WKY rat model of depression is associated with an increase in hippocampal BDNF
inferredcites →https://doi.org/10.1016/j.biopsych.2012.06.022openalex-snapshot
Rapid and Longer-Term Antidepressant Effects of Repeated Ketamine Infusions in Treatment-Resistant Major Depression
inferredcites →https://doi.org/10.1016/j.biopsych.2015.12.025openalex-snapshot
Sex Differences in Effects of Ketamine on Behavior, Spine Density, and Synaptic Proteins in Socially Isolated Rats
inferredcites →https://doi.org/10.1016/j.brainres.2004.06.052openalex-snapshot
A distinct neurochemical profile in WKY rats at baseline and in response to acute stress: implications for animal models of anxiety and depression
inferredcites →https://doi.org/10.1016/j.brainres.2007.05.042openalex-snapshot
The effects of chronic stress on hippocampal morphology and function: An evaluation of chronic restraint paradigms
inferredcites →https://doi.org/10.1016/j.celrep.2018.05.022openalex-snapshot
Psychedelics Promote Structural and Functional Neural Plasticity
inferredcites →https://doi.org/10.1016/j.jneumeth.2010.12.015openalex-snapshot
Repeated rat-forced swim test: Reducing the number of animals to evaluate gradual effects of antidepressants
inferredcites →https://doi.org/10.1016/j.lfs.2014.02.014openalex-snapshot
The role of mTOR in depression and antidepressant responses
inferredcites →https://doi.org/10.1016/j.mce.2012.08.022openalex-snapshot
Activation of Akt through 5-HT2A receptor ameliorates serotonin-induced degradation of insulin receptor substrate-1 in adipocytes
inferredcites →https://doi.org/10.1016/j.neuropharm.2013.04.044openalex-snapshot
Upregulation of the dorsal raphe nucleus-prefrontal cortex serotonin system by chronic treatment with escitalopram in hyposerotonergic Wistar-Kyoto rats
inferredcites →https://doi.org/10.1016/j.neuroscience.2010.04.035openalex-snapshot
Chronic fluoxetine treatment induces structural plasticity and selective changes in glutamate receptor subunits in the rat cerebral cortex
inferredcites →https://doi.org/10.1016/j.neuroscience.2012.03.052openalex-snapshot
Antidepressant-like effects of low ketamine dose is associated with increased hippocampal AMPA/NMDA receptor density ratio in female Wistar–Kyoto rats
inferredcites →https://doi.org/10.1016/j.pnpbp.2010.02.008openalex-snapshot
Sex differences in the effects of N,N-diethyllysergamide (LSD) on behavioural activity and prepulse inhibition
inferredcites →https://doi.org/10.1016/j.pnpbp.2011.05.010openalex-snapshot
The mTOR signaling pathway in the prefrontal cortex is compromised in major depressive disorder
inferredcites →https://doi.org/10.1016/j.pnpbp.2012.05.018openalex-snapshot
Chronic restraint stress causes anxiety- and depression-like behaviors, downregulates glucocorticoid receptor expression, and attenuates glutamate release induced by brain-derived neurotrophic factor in the prefrontal cortex
inferredcites →https://doi.org/10.1016/j.pnpbp.2017.03.016openalex-snapshot
The anti-inflammatory mechanism of antidepressants – SSRIs, SNRIs
inferredcites →https://doi.org/10.1016/j.pnpbp.2017.09.012openalex-snapshot
Serotonergic hallucinogens in the treatment of anxiety and depression in patients suffering from a life-threatening disease: A systematic review
inferredcites →https://doi.org/10.1016/s0014-2999(97)01276-4openalex-snapshot
Are Wistar-Kyoto rats a genetic animal model of depression resistant to antidepressants?
inferredcites →https://doi.org/10.1016/s0169-328x(99)00274-0openalex-snapshot
The Flinders Sensitive Line rats, a genetic model of depression, show abnormal serotonin receptor mRNA expression in the brain that is reversed by 17β-estradiol
inferredcites →https://doi.org/10.1016/s0306-4530(01)00052-xopenalex-snapshot
Amplified behavioral and endocrine responses to forced swim stress in the Wistar–Kyoto rat
inferredcites →https://doi.org/10.1016/s0893-133x(99)00100-1openalex-snapshot
Strain Differences in the Behavioral Effects of Antidepressant Drugs in the Rat Forced Swimming Test
inferredcites →https://doi.org/10.1016/s2215-0366(16)30065-7openalex-snapshot
Psilocybin with psychological support for treatment-resistant depression: an open-label feasibility study
inferredcites →https://doi.org/10.1017/neu.2019.15openalex-snapshot
Psilocybin lacks antidepressant-like effect in the Flinders Sensitive Line rat
inferredcites →https://doi.org/10.1021/acschemneuro.8b00134openalex-snapshot
Effects of N,N-Dimethyltryptamine on Rat Behaviors Relevant to Anxiety and Depression
inferredcites →https://doi.org/10.1037/pha0000119openalex-snapshot
Adolescent chronic restraint stress (aCRS) elicits robust depressive-like behavior in freely cycling, adult female rats without increasing anxiety-like behaviors.
inferredcites →https://doi.org/10.1038/266730a0openalex-snapshot
Depression: a new animal model sensitive to antidepressant treatments
inferredcites →https://doi.org/10.1038/npp.2009.183openalex-snapshot
Antidepressant-Like Effects of κ-Opioid Receptor Antagonists in Wistar Kyoto Rats
inferredcites →https://doi.org/10.1038/nprot.2007.44openalex-snapshot
The use of the elevated plus maze as an assay of anxiety-related behavior in rodents
inferredcites →https://doi.org/10.1038/nprot.2012.044openalex-snapshot
Using the rat forced swim test to assess antidepressant-like activity in rodents
inferredcites →https://doi.org/10.1038/s41586-019-1075-9openalex-snapshot
Oxytocin-dependent reopening of a social reward learning critical period with MDMA
inferredcites →https://doi.org/10.1073/pnas.1200506109openalex-snapshot
Rat brains also have a default mode network
inferredcites →https://doi.org/10.1080/09540261.2018.1474185openalex-snapshot
Awe: a putative mechanism underlying the effects of classic psychedelic-assisted psychotherapy
inferredcites →https://doi.org/10.1093/ijnp/pyw089openalex-snapshot
Rapid and Sustained Antidepressant Action of the mGlu2/3 Receptor Antagonist MGS0039 in the Social Defeat Stress Model: Comparison with Ketamine
inferredcites →https://doi.org/10.1097/jcp.0000000000000894openalex-snapshot
Maintenance Ketamine Therapy for Treatment-Resistant Depression
inferredcites →https://doi.org/10.1111/bph.12710openalex-snapshot
Sex differences in animal models of psychiatric disorders
inferredcites →https://doi.org/10.1111/j.1742-7843.2009.00516.xopenalex-snapshot
Sex Differences in Animal Models of Depression and Antidepressant Response
inferredcites →https://doi.org/10.1126/science.1190287openalex-snapshot
mTOR-Dependent Synapse Formation Underlies the Rapid Antidepressant Effects of NMDA Antagonists
inferredcites →https://doi.org/10.1152/ajpregu.2001.281.3.r786openalex-snapshot
Altered hormone levels and circadian rhythm of activity in the WKY rat, a putative animal model of depression
inferredcites →https://doi.org/10.1166/jpsp.2015.1064openalex-snapshot
Acute Cytisine and Diarylpropionitrile Independently and Additively Reduce Depressive-Like Behavior in Female Ovariectomized Rats
inferredcites →https://doi.org/10.1177/0269881114531666openalex-snapshot
Repeated lysergic acid diethylamide in an animal model of depression: Normalisation of learning behaviour and hippocampal serotonin 5-HT 2 signalling
inferredcites →https://doi.org/10.1177/0269881116675512openalex-snapshot
Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial
inferredcites →https://doi.org/10.1177/070674371005500303openalex-snapshot
The Sequenced Treatment Alternatives to Relieve Depression (STAR*D) Trial: A Review
inferredcites →https://doi.org/10.1371/journal.pone.0194215openalex-snapshot
Visual recognition of mirror, video-recorded, and still images in rats
inferredcites →https://doi.org/10.2165/11633130-000000000-00000openalex-snapshot
Targeting the Glutamatergic System to Treat Major Depressive Disorder
inferredcites →https://doi.org/10.3171/2012.5.jns112224openalex-snapshot
Effects of aging on behavioral assessment performance: implications for clinically relevant models of neurological disease
inferredcites →https://doi.org/10.3389/fphar.2017.00974openalex-snapshot
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression
inferredcites →https://doi.org/10.3389/fphar.2017.00978openalex-snapshot
S-Ketamine Mediates Its Acute and Sustained Antidepressant-Like Activity through a 5-HT1B Receptor Dependent Mechanism in a Genetic Rat Model of Depression
inferredcites →https://doi.org/10.3390/ijerph15040771openalex-snapshot
Predictors of Response to Ketamine in Treatment Resistant Major Depressive Disorder and Bipolar Disorder
inferredcites →https://doi.org/10.4088/jcp.14f09432openalex-snapshot
Antidepressant Augmentation With Anti-Inflammatory Agents
inferredcites →https://doi.org/10.4103/0976-0105.177703openalex-snapshot
A simple practice guide for dose conversion between animals and human
What points at this work
Incoming claims: where this work appears in other papers’ reference lists and arguments.
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Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease: An Open-Label Pilot Trial
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Psychedelic Drugs in Mental Disorders: Current Clinical Scope and Deep Learning‐Based Advanced Perspectives
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The changing outlook of psychedelic drugs: The importance of risk assessment and occupational exposure limits
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Hallucinogenic drugs and their potential for treating fear‐related disorders: Through the lens of fear extinction
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Contribution of the Serotonin 5‐ HT 2A Receptor to the Therapeutic Effect of Psilocin on Social Behavior Deficits in Mice Repeatedly Exposed to Social Defeat Stress
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Ethopharmacological evaluation of antidepressant-like effect of serotonergic psychedelics in C57BL/6J male mice
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The role of serotonin neurotransmission in rapid antidepressant actions
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Psilocybin mitigates the cognitive deficits observed in a rat model of Fragile X syndrome
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Probing the antidepressant potential of psilocybin: integrating insight from human research and animal models towards an understanding of neural circuit mechanisms
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Content analysis of Reddit posts about coadministration of selective serotonin reuptake inhibitors and psilocybin mushrooms
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Unraveling psilocybin’s therapeutic potential: behavioral and neuroplasticity insights in Wistar-Kyoto and Wistar male rat models of treatment-resistant depression
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Resetting the hippocampal buffer: a neurocognitive account of psychedelic therapy for anxiety-related psychopathology
inferred← citeshttps://doi.org/10.1007/s00213-026-07188-4openalex-snapshot
Acute anxiogenic effects of psilocybin and the related tryptamine, norbaeocystin, in male and female rats
inferred← citeshttps://doi.org/10.1007/s00406-023-01699-3openalex-snapshot
Psilocybin does not induce the vulnerability marker HSP70 in neurons susceptible to Olney’s lesions
inferred← citeshttps://doi.org/10.1007/s00702-026-03287-wopenalex-snapshot
Single ayahuasca administration mitigates long-term behavioral and neurochemical effects of early-life stress in rats
inferred← citeshttps://doi.org/10.1007/s11920-022-01361-0openalex-snapshot
Psilocybin Efficacy and Mechanisms of Action in Major Depressive Disorder: a Review
inferred← citeshttps://doi.org/10.1007/s40263-021-00877-yopenalex-snapshot
Molecular Mechanisms of Psilocybin and Implications for the Treatment of Depression
inferred← citeshttps://doi.org/10.1007/s40263-022-00944-yopenalex-snapshot
A Research Domain Criteria (RDoC)-Guided Dashboard to Review Psilocybin Target Domains: A Systematic Review
inferred← citeshttps://doi.org/10.1007/s40263-023-01008-5openalex-snapshot
Lysergic Acid Diethylamide (LSD) for the Treatment of Anxiety Disorders: Preclinical and Clinical Evidence
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The effects of Lysergic Acid Diethylamide (LSD) on the Positive Valence Systems: A Research Domain Criteria (RDoC)-Informed Systematic Review
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The Therapeutic Effects of Classic Psychedelics in Alcohol Use Disorder
inferred← citeshttps://doi.org/10.1007/s40501-021-00249-9openalex-snapshot
Modulating Neuroplasticity: Lessons Learned from Antidepressants and Emerging Novel Therapeutics
inferred← citeshttps://doi.org/10.1007/s43440-023-00542-9openalex-snapshot
Preclinical models of treatment-resistant depression: challenges and perspectives
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Fast-acting antidepressant-like effects of ketamine in aged male rats
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Effects of psilocybin and chronic mild stress on microglial activation in rat spinal cord: an ex vivo analysis
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Epigenetic Approaches to Behavioral Neuroscience
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Psychedelics in psychiatry
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Current and future directions of drug delivery for the treatment of mental illnesses
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Effect of psilocybin on decision-making and motivation in the healthy rat
inferred← citeshttps://doi.org/10.1016/j.bcp.2022.115028openalex-snapshot
“Selective” serotonin 5-HT2A receptor antagonists
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Serotonin 5-HT2A, 5-HT2c and 5-HT1A receptor involvement in the acute effects of psilocybin in mice. In vitro pharmacological profile and modulation of thermoregulation and head-twich response
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LSD's rapid antidepressant effects are modulated by 5-HT2B receptors
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118720openalex-snapshot
Psilocybin as a fast-acting and long-lasting antidepressant for adolescence: Proposing NeuroD1 as a biomarker of its long-term plasticity
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Prolonged epigenomic and synaptic plasticity alterations following single exposure to a psychedelic in mice
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A non-hallucinogenic LSD analog with therapeutic potential for mood disorders
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Mechanisms of enhancer function in neuronal systems in health and disease
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Mice lacking the serotonin transporter do not respond to the behavioural effects of psilocybin
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Natural psychedelics in the treatment of depression; a review focusing on neurotransmitters
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Psilocybin induces acute anxiety and changes in amygdalar phosphopeptides independently from the 5-HT2A receptor
inferred← citeshttps://doi.org/10.1016/j.jad.2022.12.042openalex-snapshot
Subtypes of the psychedelic experience have reproducible and predictable effects on depression and anxiety symptoms
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If the Doors of Perception Were Cleansed, Would Chronic Pain be Relieved? Evaluating the Benefits and Risks of Psychedelics
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Utility of preclinical models in the study of psilocybin – A comprehensive review
inferred← citeshttps://doi.org/10.1016/j.neubiorev.2024.105899openalex-snapshot
Psychedelics: A review of their effects on recalled aversive memories and fear/anxiety expression in rodents
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The effect of psychedelic microdosing on animal behavior: A review with recommendations for the field
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Classic psychedelics and autism spectrum disorder: preclinical evidence, mechanistic insights and unresolved challenges
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Ventral hippocampal parvalbumin interneurons gate the acute anxiolytic action of the serotonergic psychedelic DOI
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Ketamine induces plasticity in a norepinephrine-astroglial circuit to promote behavioral perseverance
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Preclinical perspectives on the mechanisms underlying the therapeutic actions of psilocybin in psychiatric disorders
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Single administration of a psychedelic [(R)-DOI] influences coping strategies to an escapable social stress
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Psilocybin reduces grooming in the SAPAP3 knockout mouse model of compulsive behaviour
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Concurrent stress modulates the acute and post-acute effects of psilocybin in a sex-dependent manner
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Effect of a single psilocybin treatment on Fos protein expression in male rat brain
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Biased agonism in drug discovery: Is there a future for biased 5-HT1A receptor agonists in the treatment of neuropsychiatric diseases?
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Molecular mechanisms of rapid-acting antidepressants: New perspectives for developing antidepressants
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Depression: Biological markers and treatment
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Modulation of DNA methylation and protein expression in the prefrontal cortex by repeated administration of D-lysergic acid diethylamide (LSD): Impact on neurotropic, neurotrophic, and neuroplasticity signaling
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Clinical and preclinical evidence of psilocybin as antidepressant. A narrative review
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The effect of low-dose psilocybin on brain neurotransmission and rat behavior
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Psilocybin has a narrow therapeutic window as an antidepressant treatment
inferred← citeshttps://doi.org/10.1016/j.pnpbp.2025.111508openalex-snapshot
Psilocybin-assisted psychotherapy in adults with depression – A literature review
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Changing your mind: neuroplastic mechanisms underlying the therapeutic effect of psychedelics in depression, PTSD, and addiction
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The astrocytes in the prefrontal cortex contribute to the rapid antidepressant-like effects of psilocybin in the chronic restraint stress mouse model
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Psilocybin restores behavioral and neuroplastic deficits induced by chronic stress in rats
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Psilocybin selectively suppresses novelty-induced grooming via 5-HT2B receptors: A microstructure analysis in Wistar rats
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Esketamine inhaled as dry powder: Pharmacokinetic, pharmacodynamic and safety assessment in a preclinical study
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Neuroplasticity as a convergent mechanism of ketamine and classical psychedelics
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A perspective on psychedelic teratogenicity: the utility of zebrafish models
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Psychiatric Applications of Psychedelics
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The need for guidance in antidepressant drug development: Revisiting the role of the forced swim test and tail suspension test
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Is there a place for psychedelics in sports practice?
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Psilocybin in neuropsychiatry: a review of its pharmacology, safety, and efficacy
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Biochemical Mechanisms Underlying Psychedelic-Induced Neuroplasticity
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Serotonin 2A Receptor (5-HT 2A R) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants
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Pharmahuasca and DMT Rescue ROS Production and Differentially Expressed Genes Observed after Predator and Psychosocial Stress: Relevance to Human PTSD
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Tolerance and Cross-Tolerance among Psychedelic and Nonpsychedelic 5-HT2A Receptor Agonists in Mice
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5-HT2ARs Mediate Therapeutic Behavioral Effects of Psychedelic Tryptamines
inferred← citeshttps://doi.org/10.1021/acschemneuro.3c00108openalex-snapshot
Antidepressant-like Effect of 1-(2-(4-(4-Ethylphenyl)-1H-1,2,3-triazol-1-yl)phenyl)ethan-1-one in Mice: Evidence of the Contribution of the Serotonergic System
inferred← citeshttps://doi.org/10.1021/acschemneuro.4c00058openalex-snapshot
RE104: Synthesis and Activity of a Novel Serotonergic Psychedelic Prodrug of 4-Hydroxy-N,N-diisopropyltryptamine
inferred← citeshttps://doi.org/10.1021/acschemneuro.6c00202openalex-snapshot
Short- and Long-Acting Psychedelics: Structure–Activity Relationships, Pharmacology, and Implications for Neuropsychiatric Therapeutics
inferred← citeshttps://doi.org/10.1021/acsptsci.0c00065openalex-snapshot
Transient Stimulation with Psychoplastogens Is Sufficient to Initiate Neuronal Growth
inferred← citeshttps://doi.org/10.1021/acsptsci.0c00194openalex-snapshot
The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects
inferred← citeshttps://doi.org/10.1021/acsptsci.3c00123openalex-snapshot
Transient Elevation of Plasma Glucocorticoids Supports Psilocybin-Induced Anxiolysis in Mice
inferred← citeshttps://doi.org/10.1021/acsptsci.5c00208openalex-snapshot
The Selective Serotonin 5-HT2A Receptor Agonist (S)-3-(2,5-Dimethoxy-4-(trifluoromethyl)phenyl)piperidine (LPH-5) Induces Persistent and Robust Antidepressant-Like Effects in Rodents
inferred← citeshttps://doi.org/10.1038/s41380-022-01832-zopenalex-snapshot
Could psychedelic drugs have a role in the treatment of schizophrenia? Rationale and strategy for safe implementation
inferred← citeshttps://doi.org/10.1038/s41380-023-02274-xopenalex-snapshot
Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics
inferred← citeshttps://doi.org/10.1038/s41380-023-02391-7openalex-snapshot
High-resolution tracking of unconfined zebrafish behavior reveals stimulatory and anxiolytic effects of psilocybin
inferred← citeshttps://doi.org/10.1038/s41380-025-03005-0openalex-snapshot
Letter to the editor: Comments on ‘Striking long-term beneficial effects of single-dose psilocybin and psychedelic mushroom extract in the SAPAP3 rodent model of OCD-like excessive self-grooming’ by Brownstien et al. (2024)
inferred← citeshttps://doi.org/10.1038/s41380-025-03308-2openalex-snapshot
Neuropharmacology of halogenated DMT analogs: psychoplastogenic and antidepressant properties of 5-Br-DMT, a psychedelic derivative with low hallucinogenic potential
inferred← citeshttps://doi.org/10.1038/s41380-025-03387-1openalex-snapshot
The serotonin 1B receptor is required for some of the behavioral effects of psilocybin in mice
inferred← citeshttps://doi.org/10.1038/s41386-020-0694-zopenalex-snapshot
Psilocybin and LSD have no long-lasting effects in an animal model of alcohol relapse
inferred← citeshttps://doi.org/10.1038/s41386-022-01301-9openalex-snapshot
Repeated lysergic acid diethylamide (LSD) reverses stress-induced anxiety-like behavior, cortical synaptogenesis deficits and serotonergic neurotransmission decline
inferred← citeshttps://doi.org/10.1038/s41386-023-01613-4openalex-snapshot
UNRAVELing the synergistic effects of psilocybin and environment on brain-wide immediate early gene expression in mice
inferred← citeshttps://doi.org/10.1038/s41386-023-01666-5openalex-snapshot
Therapeutic mechanisms of psychedelics and entactogens
inferred← citeshttps://doi.org/10.1038/s41386-025-02272-3openalex-snapshot
Psychedelics produce enduring behavioral effects and functional plasticity through mechanisms independent of structural plasticity
inferred← citeshttps://doi.org/10.1038/s41386-026-02361-xopenalex-snapshot
Psilocybin improves novel object recognition in a rat model of Fragile X Syndrome through the modulation of the BDNF/TrkB signaling pathway
inferred← citeshttps://doi.org/10.1038/s41398-022-01846-9openalex-snapshot
Psilocin acutely alters sleep-wake architecture and cortical brain activity in laboratory mice
inferred← citeshttps://doi.org/10.1038/s41398-023-02414-5openalex-snapshot
Sex-specific effects of psychedelic drug exposure on central amygdala reactivity and behavioral responding
inferred← citeshttps://doi.org/10.1038/s41398-025-03421-4openalex-snapshot
Evaluation of behavioural and neurochemical effects of psilocybin in mice subjected to chronic unpredictable mild stress
inferred← citeshttps://doi.org/10.1038/s41398-026-03995-7openalex-snapshot
Effects of a single dose of psilocybin on diet-induced weight loss in obese mice
inferred← citeshttps://doi.org/10.1038/s41467-025-58239-xopenalex-snapshot
Structural basis for psilocybin biosynthesis
inferred← citeshttps://doi.org/10.1038/s41592-024-02375-7openalex-snapshot
Rapid, biochemical tagging of cellular activity history in vivo
inferred← citeshttps://doi.org/10.1038/s41593-022-01177-4openalex-snapshot
The neural basis of psychedelic action
inferred← citeshttps://doi.org/10.1038/s41593-023-01316-5openalex-snapshot
Psychedelics promote plasticity by directly binding to BDNF receptor TrkB
inferred← citeshttps://doi.org/10.1038/s41593-025-02021-1openalex-snapshot
The psychoplastogen tabernanthalog induces neuroplasticity without proximate immediate early gene activation
inferred← citeshttps://doi.org/10.1038/s41598-022-14165-2openalex-snapshot
Validation of the forced swim test in Drosophila, and its use to demonstrate psilocybin has long-lasting antidepressant-like effects in flies
inferred← citeshttps://doi.org/10.1038/s44159-024-00345-6openalex-snapshot
Clinically relevant acute subjective effects of psychedelics beyond mystical experience
inferred← citeshttps://doi.org/10.1039/d4cc03892dopenalex-snapshot
Photoswitchable TCB-2 for control of the 5-HT 2A receptor and analysis of biased agonism
inferred← citeshttps://doi.org/10.1073/pnas.2020705118openalex-snapshot
Lysergic acid diethylamide (LSD) promotes social behavior through mTORC1 in the excitatory neurotransmission
inferred← citeshttps://doi.org/10.1073/pnas.2022489118openalex-snapshot
Harnessing psilocybin: antidepressant-like behavioral and synaptic actions of psilocybin are independent of 5-HT2R activation in mice
inferred← citeshttps://doi.org/10.1073/pnas.2416106122openalex-snapshot
Molecular design of a therapeutic LSD analogue with reduced hallucinogenic potential
inferred← citeshttps://doi.org/10.1080/02791072.2025.2607726openalex-snapshot
Daily Administration of Psilocin Mucate (L-130) Produces a Favorable Safety Profile and Anxiolytic Effects in Rodents Exposed to Chronic Unpredictable Mild Stress
inferred← citeshttps://doi.org/10.1080/13543784.2022.2113376openalex-snapshot
New investigational agents for the treatment of major depressive disorder
inferred← citeshttps://doi.org/10.1080/17460441.2022.2111415openalex-snapshot
Where do we go next in antidepressant drug discovery? A new generation of antidepressants: a pivotal role of AMPA receptor potentiation and mGlu2/3 receptor antagonism
inferred← citeshttps://doi.org/10.1080/17460441.2025.2460674openalex-snapshot
Investigating novel pharmacological strategies for treatment-resistant depression: focus on new mechanisms and approaches
inferred← citeshttps://doi.org/10.1080/19585969.2025.2480566openalex-snapshot
Exploring novel therapeutic strategies: Could psychedelic perspectives offer promising solutions for Alzheimer’s disease comorbidities?
inferred← citeshttps://doi.org/10.1089/psymed.2022.0012openalex-snapshot
A Single Administration of Psilocybin Persistently Rescues Cognitive Deficits Caused by Adolescent Chronic Restraint Stress Without Long-Term Changes in Synaptic Protein Gene Expression in a Rat Experimental System with Translational Relevance to Depression
inferred← citeshttps://doi.org/10.1089/psymed.2023.0010openalex-snapshot
Learned Helplessness As a Potential Transdiagnostic Therapeutic Mechanism of Classic Psychedelics
inferred← citeshttps://doi.org/10.1089/psymed.2023.0037openalex-snapshot
Preadministration of Lorazepam Reduces Efficacy and Longevity of Antidepressant-Like Effect from a Psychedelic
inferred← citeshttps://doi.org/10.1093/brain/awab406openalex-snapshot
Models of psychedelic drug action: modulation of cortical-subcortical circuits
inferred← citeshttps://doi.org/10.1093/ijnp/pyaa087openalex-snapshot
Ketamine and Serotonergic Psychedelics: Common Mechanisms Underlying the Effects of Rapid-Acting Antidepressants
inferred← citeshttps://doi.org/10.1093/oso/9780192898371.003.0007openalex-snapshot
Classic psychedelics in translational research: addressing epistemic challenges from bench to bedside
inferred← citeshttps://doi.org/10.1097/gh9.0000000000000089openalex-snapshot
The psychedelic renaissance: can psilocybin possibly combat depression?
inferred← citeshttps://doi.org/10.1101/2020.08.12.248229openalex-snapshot
Delayed Anxiolytic-Like Effects of Psilocybin in Male Mice Are Supported by Acute Glucocorticoid Release
inferred← citeshttps://doi.org/10.1101/2021.02.16.431276openalex-snapshot
Psilocin acutely disrupts sleep and affects local but not global sleep homeostasis in laboratory mice
inferred← citeshttps://doi.org/10.1101/2021.02.24.432725openalex-snapshot
Prolonged epigenetic and synaptic plasticity alterations following single exposure to a psychedelic in mice
inferred← citeshttps://doi.org/10.1101/2022.12.29.522099openalex-snapshot
Ketamine modulates a norepinephrine-astroglial circuit to persistently suppress futility-induced passivity
inferred← citeshttps://doi.org/10.1101/2024.01.04.574146openalex-snapshot
Behavioural Investigations of Psilocybin in Animals 1962-2021: A Scoping Review
inferred← citeshttps://doi.org/10.1101/2024.04.19.590212openalex-snapshot
The selective 5-HT 2A receptor agonist LPH-5 induces persistent and robust antidepressant-like effects in rodents
inferred← citeshttps://doi.org/10.1101/2024.12.20.629571openalex-snapshot
Characterizing psilocybin as an antidepressant for adolescence in male and female rats
inferred← citeshttps://doi.org/10.1101/2025.04.08.647810openalex-snapshot
A multi-institutional investigation of psilocybin’s effects on mouse behavior
inferred← citeshttps://doi.org/10.1108/k-01-2023-0083openalex-snapshot
TOTEs and trauma 2: a rat maternal care and stress epigenetic schematic
inferred← citeshttps://doi.org/10.1111/bph.16466openalex-snapshot
Pharmacological and behavioural effects of tryptamines present in psilocybin‐containing mushrooms
inferred← citeshttps://doi.org/10.1111/bph.17370openalex-snapshot
Preclinical models for evaluating psychedelics in the treatment of major depressive disorder
inferred← citeshttps://doi.org/10.1111/bph.70050openalex-snapshot
Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT 2A receptor agonists
inferred← citeshttps://doi.org/10.1111/ejn.16421openalex-snapshot
Psychedelic therapy in depression and substance use disorders
inferred← citeshttps://doi.org/10.1111/ejn.70351openalex-snapshot
Acute Blockade of the Serotonin Transporter With Low Doses of Escitalopram Does Not Alter the Behavioural Responses to Acute Psilocybin
inferred← citeshttps://doi.org/10.1111/fcp.70038openalex-snapshot
Psilocybin as Transformative Fast‐Acting Antidepressant: Pharmacological Properties and Molecular Mechanisms
inferred← citeshttps://doi.org/10.1111/jnc.15536openalex-snapshot
Molecular targets of psychedelic‐induced plasticity
inferred← citeshttps://doi.org/10.1111/jnc.15544openalex-snapshot
Psychedelic‐inspired approaches for treating neurodegenerative disorders
inferred← citeshttps://doi.org/10.1111/jnc.16017openalex-snapshot
Psilocybin as a lead candidate molecule in preclinical therapeutic studies of psychiatric disorders: A systematic review
inferred← citeshttps://doi.org/10.1124/jpet.124.002237openalex-snapshot
Evaluating the potential for psilocybin as a treatment for post-traumatic stress disorder
inferred← citeshttps://doi.org/10.1124/pharmrev.120.000056openalex-snapshot
Psychedelics in Psychiatry: Neuroplastic, Immunomodulatory, and Neurotransmitter Mechanisms
inferred← citeshttps://doi.org/10.1124/pharmrev.121.000508openalex-snapshot
Neural Mechanisms and Psychology of Psychedelic Ego Dissolution
inferred← citeshttps://doi.org/10.1124/pharmrev.122.000590openalex-snapshot
Animal Behavior in Psychedelic Research
inferred← citeshttps://doi.org/10.1126/science.adl0666openalex-snapshot
Isolation of psychedelic-responsive neurons underlying anxiolytic behavioral states
inferred← citeshttps://doi.org/10.1126/scisignal.adw6055openalex-snapshot
Design of a new psychedelic quipazine analog with therapeutic efficacy and potentially fewer side effects
inferred← citeshttps://doi.org/10.1177/0269881120959614openalex-snapshot
Transcriptional regulation in the rat prefrontal cortex and hippocampus after a single administration of psilocybin
inferred← citeshttps://doi.org/10.1177/0269881120986422openalex-snapshot
Hallucinogenic/psychedelic 5HT2A receptor agonists as rapid antidepressant therapeutics: Evidence and mechanisms of action
inferred← citeshttps://doi.org/10.1177/02698811231205692openalex-snapshot
Acute but not long-lasting antidepressant-like effect of psilocybin in differential reinforcement of low-rate 72 schedule in rats
inferred← citeshttps://doi.org/10.1177/02698811241249436openalex-snapshot
Psilocybin promotes neuroplasticity and induces rapid and sustained antidepressant-like effects in mice
inferred← citeshttps://doi.org/10.1177/02698811251330783openalex-snapshot
Psilocybin and ketamine affect novel neuropeptides gene expression in the rat hypothalamus
inferred← citeshttps://doi.org/10.1177/02698811251360754openalex-snapshot
Appraisal of the validity of preclinical investigations to predict the efficacy of psychedelic drugs as fast-acting antidepressants
inferred← citeshttps://doi.org/10.1177/02698811251368361openalex-snapshot
High dose of psilocybin induces acute behavioral changes without inducing conditioned place preference in Sprague-Dawley rats
inferred← citeshttps://doi.org/10.1177/02698811251395386openalex-snapshot
An exploration of the relationships between the effects of psilocybin on behavior, 5-HT 2A receptor occupancy, and neuroplastic effects in mice
inferred← citeshttps://doi.org/10.1177/02698811261458349openalex-snapshot
Blocking 5-HT2B receptors abolishes psilocybin’s efficacy in the rat forced swim test
inferred← citeshttps://doi.org/10.1177/13634615221129116openalex-snapshot
Psychosis and psychedelics: Historical entanglements and contemporary contrasts
inferred← citeshttps://doi.org/10.1177/23982128221081645openalex-snapshot
A systematic review of studies investigating the acute effects of N -methyl- D -aspartate receptor antagonists on behavioural despair in normal animals suggests poor predictive validity
inferred← citeshttps://doi.org/10.1177/28314425251393186openalex-snapshot
Preadministration of Lorazepam Negates the Long-Term Antidepressant-Like Effects of Psilocybin in Male Wistar Kyoto Rats
inferred← citeshttps://doi.org/10.1254/fpj.22141openalex-snapshot
Contribution of serotonin 5-HT2A receptor to antidepressant effect of serotonergic psychedelics
inferred← citeshttps://doi.org/10.1523/jneurosci.1316-22.2022openalex-snapshot
NMDA Receptor Activation-Dependent Antidepressant-Relevant Behavioral and Synaptic Actions of Ketamine
inferred← citeshttps://doi.org/10.1523/jneurosci.1659-20.2020openalex-snapshot
Hallucinogens in Mental Health: Preclinical and Clinical Studies on LSD, Psilocybin, MDMA, and Ketamine
inferred← citeshttps://doi.org/10.1556/2054.2025.00364openalex-snapshot
Behavioural investigations of psilocybin in non-human animals 1962–2021: A scoping review
inferred← citeshttps://doi.org/10.2174/1568026623666230705151922openalex-snapshot
Addressing the Current Knowledge and Gaps in Research Surrounding Lysergic Acid Diethylamide (LSD), Psilocybin, and Psilocin in Rodent Models
inferred← citeshttps://doi.org/10.2174/2772432817666220321142707openalex-snapshot
Using Psychedelics in Clinical Practice: Comparing Therapeutic Uses and Potential Harms
inferred← citeshttps://doi.org/10.22271/27069567.2021.v3.i1f.159openalex-snapshot
Unmet need in depression: Psilocybin, a breakthrough treatment option
inferred← citeshttps://doi.org/10.24839/2325-7342.jn27.3.185openalex-snapshot
Well-Being and the Outdoors: An Environmentalism Study Among a Religious Student Population
inferred← citeshttps://doi.org/10.24839/2325-7342.jn27.3.223openalex-snapshot
INVITED EDITORIAL: Sharing Effective Models of Student Research Mentoring: Stories From Associate Editors
inferred← citeshttps://doi.org/10.26686/wgtn.19579795openalex-snapshot
The Therapeutic Efficacy of Psilocybin in a Preclinical Model of Depressive- and Anxiety-Like Symptomology
inferred← citeshttps://doi.org/10.26876/ikergazte.v.04.14openalex-snapshot
Psilozibinaren administrazio akutuaren eraginen ebaluazioa garun kortexean serotonina, noradrenalina eta dopamina mailak neurtuz: garun-mikrodialisiaren bidez burututako ikerlana esna dauden saguetan
inferred← citeshttps://doi.org/10.31234/osf.io/xqzu2openalex-snapshot
A Quantitative and Qualitative Report of Psilocybin Induced Mystical-Type Experiences and Their Relation to Lasting Positive Effects
inferred← citeshttps://doi.org/10.31234/osf.io/ypr7wopenalex-snapshot
Therapeutic dissociation: From non-ordinary states to psychological transformation
inferred← citeshttps://doi.org/10.3138/jmvfh-2023-0014openalex-snapshot
Mechanisms of integration in psychedelic-assisted therapy
inferred← citeshttps://doi.org/10.31390/gradschool_dissertations.5761openalex-snapshot
Evaluation of Hippocampal Allostatic Load-Associated Factors in Animal Models of Post-Traumatic Stress Disorder: Relevance to Human PTSD
inferred← citeshttps://doi.org/10.32920/26052859openalex-snapshot
How Does Psilocybin Therapy Work? an Exploration of Experiential Avoidance as a Putative Mechanism of Change
inferred← citeshttps://doi.org/10.32920/26052859.v1openalex-snapshot
How Does Psilocybin Therapy Work? an Exploration of Experiential Avoidance as a Putative Mechanism of Change
inferred← citeshttps://doi.org/10.3389/fnmol.2021.748359openalex-snapshot
Serotonergic Psychedelics in Neural Plasticity
inferred← citeshttps://doi.org/10.3389/fnsys.2025.1585367openalex-snapshot
Neurobiology of psilocybin: a comprehensive overview and comparative analysis of experimental models
inferred← citeshttps://doi.org/10.3389/fpain.2024.1346053openalex-snapshot
Chronic pain as an emergent property of a complex system and the potential roles of psychedelic therapies
inferred← citeshttps://doi.org/10.3389/fphar.2020.602770openalex-snapshot
Acute Lysergic Acid Diethylamide Does Not Influence Reward-Driven Decision Making of C57BL/6 Mice in the Iowa Gambling Task
inferred← citeshttps://doi.org/10.3389/fphar.2022.841648openalex-snapshot
Psilocybin-Induced Mystical-Type Experiences are Related to Persisting Positive Effects: A Quantitative and Qualitative Report
inferred← citeshttps://doi.org/10.3389/fphar.2023.1240295openalex-snapshot
Bedside to bench: the outlook for psychedelic research
inferred← citeshttps://doi.org/10.3389/fpsyt.2020.00412openalex-snapshot
Toward a New Model of Understanding, Preventing, and Treating Adolescent Depression Focusing on Exhaustion and Stress
inferred← citeshttps://doi.org/10.3389/fpsyt.2021.727117openalex-snapshot
Psychedelics and Other Psychoplastogens for Treating Mental Illness
inferred← citeshttps://doi.org/10.3389/fpsyt.2021.800072openalex-snapshot
Psychedelic Therapy's Transdiagnostic Effects: A Research Domain Criteria (RDoC) Perspective
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.1041277openalex-snapshot
Methylone, a rapid acting entactogen with robust anxiolytic and antidepressant-like activity
inferred← citeshttps://doi.org/10.3389/fpsyt.2022.867484openalex-snapshot
Ketamine for Bipolar Depression: Biochemical, Psychotherapeutic, and Psychedelic Approaches
inferred← citeshttps://doi.org/10.3389/frspt.2022.899159openalex-snapshot
A long trip into the universe: Psychedelics and space travel
inferred← citeshttps://doi.org/10.3390/biology12111380openalex-snapshot
A Comprehensive Review of the Current Status of the Cellular Neurobiology of Psychedelics
inferred← citeshttps://doi.org/10.3390/biomedicines12122744openalex-snapshot
Neuroplasticity and Mechanisms of Action of Acute and Chronic Treatment with Antidepressants in Preclinical Studies
inferred← citeshttps://doi.org/10.3390/biomedicines14071516openalex-snapshot
Psilocibin: Current Evidence, Safety Signals, and Challenges in Assessing Potential Multi-Organ Effects
inferred← citeshttps://doi.org/10.3390/ijms23126713openalex-snapshot
Effect of Psilocybin and Ketamine on Brain Neurotransmitters, Glutamate Receptors, DNA and Rat Behavior
inferred← citeshttps://doi.org/10.3390/ijms232315284openalex-snapshot
Psychedelic-Induced Serotonin 2A Receptor Downregulation Does Not Predict Swim Stress Coping in Mice
inferred← citeshttps://doi.org/10.3390/ijms24021329openalex-snapshot
The Bright Side of Psychedelics: Latest Advances and Challenges in Neuropharmacology
inferred← citeshttps://doi.org/10.3390/ijms25010100openalex-snapshot
Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study
inferred← citeshttps://doi.org/10.3390/ijms25010241openalex-snapshot
Molecular and Medical Aspects of Psychedelics
inferred← citeshttps://doi.org/10.3390/molecules31020212openalex-snapshot
Psychedelic Drugs Rediscovered—In Silico Study of Potential Fetal Exposure to Analogues of Psychedelic Drugs During Pregnancy
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