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Development of Inhibitor-Directed Enzyme Prodrug Therapy (IDEPT) for Prostate Cancer

https://doi.org/10.1021/bc500362n
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1097-0045(20000301)42:4<318::aid-pros10>3.0.co;2-lopenalex-snapshot
Serum levels of PSMA
inferredcites →https://doi.org/10.1002/(sici)1097-0142(19980601)82:11<2256::aid-cncr22>3.0.co;2-sopenalex-snapshot
Prostate specific membrane antigen expression in prostatic intraepithelial neoplasia and adenocarcinoma
inferredcites →https://doi.org/10.1002/1097-4652(2001)9999:9999<::aid-jcp1060>3.0.co;2-hopenalex-snapshot
Gene directed enzyme/prodrug therapy of cancer: Historical appraisal and future prospectives
inferredcites →https://doi.org/10.1002/1521-3773(20010601)40:11<2004::aid-anie2004>3.0.co;2-5openalex-snapshot
Click Chemistry: Diverse Chemical Function from a Few Good Reactions
inferredcites →https://doi.org/10.1002/anie.201008178openalex-snapshot
Genetically Encoded Copper‐Free Click Chemistry
inferredcites →https://doi.org/10.1002/bit.22070openalex-snapshot
High‐level cell‐free synthesis yields of proteins containing site‐specific non‐natural amino acids
inferredcites →https://doi.org/10.1002/cmdc.200500044openalex-snapshot
Design and Synthesis of a PSMA Inhibitor–Doxorubicin Conjugate for Targeted Prostate Cancer Therapy
inferredcites →https://doi.org/10.1002/pros.20753openalex-snapshot
Cell‐Surface labeling and internalization by a fluorescent inhibitor of prostate‐specific membrane antigen
inferredcites →https://doi.org/10.1006/prep.1997.0839openalex-snapshot
Cloning, Overexpression, and Purification of Cytosine Deaminase fromSaccharomyces cerevisiae
inferredcites →https://doi.org/10.1007/s002940050169openalex-snapshot
Characterization of the Saccharomyces cerevisiae FCY1 gene encoding cytosine deaminase and its homologue FCA1 of Candida albicans
inferredcites →https://doi.org/10.1016/j.bmc.2004.06.031openalex-snapshot
Probing for a hydrophobic a binding register in prostate-specific membrane antigen with phenylalkylphosphonamidates
inferredcites →https://doi.org/10.1016/j.bmc.2005.07.056openalex-snapshot
Optimizing phenylethylphosphonamidates for the inhibition of prostate-specific membrane antigen
inferredcites →https://doi.org/10.1016/j.bmcl.2004.12.065openalex-snapshot
In vivo incorporation of an alkyne into proteins in Escherichia coli
inferredcites →https://doi.org/10.1016/j.bmcl.2011.09.115openalex-snapshot
Spacer length effects on in vitro imaging and surface accessibility of fluorescent inhibitors of prostate specific membrane antigen
inferredcites →https://doi.org/10.1016/j.bmcl.2012.04.110openalex-snapshot
Targeting prostate cancer cells with a multivalent PSMA inhibitor-guided streptavidin conjugate
inferredcites →https://doi.org/10.1016/j.jmb.2008.01.002openalex-snapshot
Yeast Cytosine Deaminase Mutants with Increased Thermostability Impart Sensitivity to 5-Fluorocytosine
inferredcites →https://doi.org/10.1016/j.jmb.2009.10.030openalex-snapshot
An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli
inferredcites →https://doi.org/10.1016/j.pep.2006.05.008openalex-snapshot
Purification of prostate-specific membrane antigen using conformational epitope-specific antibody-affinity chromatography
inferredcites →https://doi.org/10.1016/s0026-895x(25)13624-9openalex-snapshot
A first step in the development of gene therapy for colorectal carcinoma: cloning, sequencing, and expression of Escherichia coli cytosine deaminase.
inferredcites →https://doi.org/10.1016/s0090-4295(96)00184-7openalex-snapshot
Upregulation of prostate-specific membrane antigen after androgen-deprivation therapy
inferredcites →https://doi.org/10.1021/bc800077yopenalex-snapshot
In VivoTumor Cell Targeting with “Click” Nanoparticles
inferredcites →https://doi.org/10.1021/bi00799a018openalex-snapshot
Baker's yeast cytosine deaminase. Enzymic properties and allosteric inhibition by nucleosides and nucleotides
inferredcites →https://doi.org/10.1021/bi049720zopenalex-snapshot
Alanine-Scanning Mutagenesis Reveals a Cytosine Deaminase Mutant with Altered Substrate Preference
inferredcites →https://doi.org/10.1021/bi801883vopenalex-snapshot
Pseudoirreversible Inhibition of Prostate-Specific Membrane Antigen by Phosphoramidate Peptidomimetics
inferredcites →https://doi.org/10.1021/bi9007726openalex-snapshot
Click Chemistry and Bioorthogonal Reactions: Unprecedented Selectivity in the Labeling of Biological Molecules
inferredcites →https://doi.org/10.1021/ja027007wopenalex-snapshot
Addition of p -Azido- l -phenylalanine to the Genetic Code of Escherichia c oli
inferredcites →https://doi.org/10.1021/ja0370037openalex-snapshot
Adding Amino Acids with Novel Reactivity to the Genetic Code of Saccharomyces Cerevisiae
inferredcites →https://doi.org/10.1021/ja044996fopenalex-snapshot
A Strain-Promoted [3 + 2] Azide−Alkyne Cycloaddition for Covalent Modification of Biomolecules in Living Systems
inferredcites →https://doi.org/10.1021/ja303904eopenalex-snapshot
Synthesis of Bispecific Antibodies using Genetically Encoded Unnatural Amino Acids
inferredcites →https://doi.org/10.1021/ja803086ropenalex-snapshot
Second-Generation Difluorinated Cyclooctynes for Copper-Free Click Chemistry
inferredcites →https://doi.org/10.1021/jm100729bopenalex-snapshot
Synthesis and Biological Analysis of Prostate-Specific Membrane Antigen-Targeted Anticancer Prodrugs
inferredcites →https://doi.org/10.1021/jm800111uopenalex-snapshot
Synthesis and Evaluation of Technetium-99m- and Rhenium-Labeled Inhibitors of the Prostate-Specific Membrane Antigen (PSMA)
inferredcites →https://doi.org/10.1021/jo026615ropenalex-snapshot
Click Chemistry to Construct Fluorescent Oligonucleotides for DNA Sequencing
inferredcites →https://doi.org/10.1021/mp800013copenalex-snapshot
Antitumor Therapy Mediated by 5-Fluorocytosine and a Recombinant Fusion Protein Containing TSG-6 Hyaluronan Binding Domain and Yeast Cytosine Deaminase
inferredcites →https://doi.org/10.1021/mp900069dopenalex-snapshot
Prostate-Specific Membrane Antigen Targeted Imaging and Therapy of Prostate Cancer Using a PSMA Inhibitor as a Homing Ligand
inferredcites →https://doi.org/10.1038/mt.sj.6300120openalex-snapshot
Phase I Trial of Replication-competent Adenovirus-mediated Suicide Gene Therapy Combined with IMRT for Prostate Cancer
inferredcites →https://doi.org/10.1073/pnas.91.17.8302openalex-snapshot
Metabolism of 5-fluorocytosine to 5-fluorouracil in human colorectal tumor cells transduced with the cytosine deaminase gene: significant antitumor effects when only a small percentage of tumor cells express cytosine deaminase.
inferredcites →https://doi.org/10.1080/00021369.1989.10869490openalex-snapshot
Purification and Some Properties of Cytosine Deaminase from Bakers’ Yeast
inferredcites →https://doi.org/10.1093/jac/dkm389openalex-snapshot
Antifungal serum concentration monitoring: an update
inferredcites →https://doi.org/10.1093/neuonc/nor199openalex-snapshot
Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector
inferredcites →https://doi.org/10.1126/science.1107387openalex-snapshot
Computational Thermostabilization of an Enzyme
inferredcites →https://doi.org/10.1128/aac.00705-08openalex-snapshot
Antifungal Therapeutic Drug Monitoring: Established and Emerging Indications
inferredcites →https://doi.org/10.1146/annurev.biophys.35.101105.121507openalex-snapshot
EXPANDING THE GENETIC CODE
inferredcites →https://doi.org/10.1158/1078-0432.ccr-05-2729openalex-snapshot
Novel Cytosine Deaminase Fusion Gene Enhances the Effect of Radiation on Breast Cancer in Bone by Reducing Tumor Burden, Osteolysis, and Skeletal Fracture
inferredcites →https://doi.org/10.2967/jnumed.109.066589openalex-snapshot
Assessment of an 18F-Labeled Phosphoramidate Peptidomimetic as a New Prostate-Specific Membrane Antigen–Targeted Imaging Agent for Prostate Cancer

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4658486openalex-extracted
inferred← citeshttps://doi.org/10.1016/b978-0-443-15635-9.00006-7openalex-snapshot
Self-assembling prodrugs
inferred← citeshttps://doi.org/10.1016/j.bmcl.2019.01.040openalex-snapshot
Synthesis and biological evaluation of Doxorubicin-containing conjugate targeting PSMA
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129657openalex-snapshot
PSMA-targeted SMART molecules outfitted with SN38
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129712openalex-snapshot
A PSMA-targeted doxorubicin small-molecule drug conjugate
inferred← citeshttps://doi.org/10.1016/j.bmcl.2025.130213openalex-snapshot
A small-molecule pretargeting approach for PSMA-targeted conjugates
inferred← citeshttps://doi.org/10.1016/j.jpha.2025.101290openalex-snapshot
Small-molecule probes based on natural products: Elucidation of drug-target mechanisms in stroke
inferred← citeshttps://doi.org/10.1016/j.nucmedbio.2015.06.003openalex-snapshot
A high-affinity [18F]-labeled phosphoramidate peptidomimetic PSMA-targeted inhibitor for PET imaging of prostate cancer
inferred← citeshttps://doi.org/10.1039/d3nr06520kopenalex-snapshot
PSMA-targeted dendrimer as an efficient anticancer drug delivery vehicle for prostate cancer
inferred← citeshttps://doi.org/10.1111/bph.13576openalex-snapshot
The therapeutic and diagnostic potential of the prostate specific membrane antigen/glutamate carboxypeptidase II (PSMA/GCPII) in cancer and neurological disease
inferred← citeshttps://doi.org/10.1201/b20045-21openalex-snapshot
Polyester Carriers for Enzyme Delivery
inferred← citeshttps://doi.org/10.3109/07388551.2015.1048504openalex-snapshot
Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids
inferred← citeshttps://doi.org/10.3389/fonc.2024.1504514openalex-snapshot
Repurposing of PSMA-targeted diagnostic and therapeutic agents for the detection and treatment of giant cell tumors of bone
inferred← citeshttps://doi.org/10.3390/ijms241814035openalex-snapshot
Non-Canonical Amino Acids in Analyses of Protease Structure and Function
inferred← citeshttps://doi.org/10.7150/thno.18719openalex-snapshot
177Lu-Labeled Phosphoramidate-Based PSMA Inhibitors: The Effect of an Albumin Binder on Biodistribution and Therapeutic Efficacy in Prostate Tumor-Bearing Mice
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