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Pseudoirreversible Inhibition of Prostate-Specific Membrane Antigen by Phosphoramidate Peptidomimetics

https://doi.org/10.1021/bi801883v
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Outgoing claims: the papers this work cites, builds on, or argues with.

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Analysis of glycosylation of prostate-specific membrane antigen derived from LNCaP cells, prostatic carcinoma tumors, and serum from prostate cancer patients
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Characterization of the enzymatic activity of PSM: Comparison with brain NAALADase
inferredcites →https://doi.org/10.1002/pros.10117openalex-snapshot
Anti‐tumor effects of toxins targeted to the prostate specific membrane antigen
inferredcites →https://doi.org/10.1002/pros.20073openalex-snapshot
Anti‐prostate specific membrane antigen designer T cells for prostate cancer therapy
inferredcites →https://doi.org/10.1002/pros.20753openalex-snapshot
Cell‐Surface labeling and internalization by a fluorescent inhibitor of prostate‐specific membrane antigen
inferredcites →https://doi.org/10.1007/s003350010240openalex-snapshot
Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/folate hydrolase
inferredcites →https://doi.org/10.1016/j.bmc.2007.07.028openalex-snapshot
The molecular pruning of a phosphoramidate peptidomimetic inhibitor of prostate-specific membrane antigen
inferredcites →https://doi.org/10.1016/j.drudis.2007.07.010openalex-snapshot
Progress in the discovery and development of glutamate carboxypeptidase II inhibitors
inferredcites →https://doi.org/10.1016/s0090-4295(01)00983-9openalex-snapshot
Comparison of anti-prostate-specific membrane antigen antibodies and other immunomarkers in metastatic prostate carcinoma
inferredcites →https://doi.org/10.1016/s0090-4295(97)00177-5openalex-snapshot
Characterization and glutamyl preferring carboxypeptidase function of prostate specific membrane antigen: A novel folate hydrolase
inferredcites →https://doi.org/10.1021/bi048534qopenalex-snapshot
Molecular Basis of the Time-Dependent Inhibition of Cyclooxygenases by Indomethacin
inferredcites →https://doi.org/10.1038/nrd1903openalex-snapshot
NAAG peptidase inhibitors and their potential for diagnosis and therapy
inferredcites →https://doi.org/10.1038/sj.emboj.7600969openalex-snapshot
Structure of glutamate carboxypeptidase II, a drug target in neuronal damage and prostate cancer
inferredcites →https://doi.org/10.1073/pnas.93.2.749openalex-snapshot
Prostate-specific membrane antigen is a hydrolase with substrate and pharmacologic characteristics of a neuropeptidase.
inferredcites →https://doi.org/10.1091/mbc.e02-11-0731openalex-snapshot
A Novel Cytoplasmic Tail MXXXL Motif Mediates the Internalization of Prostate-specific Membrane Antigen
inferredcites →https://doi.org/10.1128/mcb.00084-06openalex-snapshot
Prostate-Specific Membrane Antigen Regulates Angiogenesis by Modulating Integrin Signal Transduction
inferredcites →https://doi.org/10.1158/1078-0432.ccr-04-2690openalex-snapshot
Radiolabeled Small-Molecule Ligands for Prostate-Specific Membrane Antigen:In vivoImaging in Experimental Models of Prostate Cancer
inferredcites →https://doi.org/10.1200/jco.2005.05.160openalex-snapshot
Phase I Trial of 177 Lutetium-Labeled J591, a Monoclonal Antibody to Prostate-Specific Membrane Antigen, in Patients With Androgen-Independent Prostate Cancer
inferredcites →https://doi.org/10.1615/critrevimmunol.v21.i1-3.160openalex-snapshot
A Unique Folate Hydrolase, Prostate-Specific Membrane Antigen (PSMA): A Target For Immunotherapy?

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Recent Development of Diagnostic and Therapeutic Agents Targeting Glutamate Carboxypeptidase II (GCPII)
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Flow cytometric detection of prostate tumor cells using chemoaffinity labels
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A phosphoramidate‐based prostate‐specific membrane antigen‐targeted SPECT agent
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Chemoaffinity capture of pre‐targeted prostate cancer cells with magnetic beads
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PSMA‐targeted SPECT agents: Mode of binding effect on in vitro performance
inferred← citeshttps://doi.org/10.1002/pros.22727openalex-snapshot
Biochemical characterization of prostate-specific membrane antigen from canine prostate carcinoma cells
inferred← citeshttps://doi.org/10.1002/pros.22784openalex-snapshot
Preclinical evaluation of a bispecific low‐molecular heterodimer targeting both PSMA and GRPR for improved PET imaging and therapy of prostate cancer
inferred← citeshttps://doi.org/10.1002/slct.202506967openalex-snapshot
Synthesis and Evaluation of 99m Tc Essential Analogue of DUPA PSMA Inhibitor for Its Potential Use in Prostate Cancer Imaging
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PSMA as a target for radiolabelled small molecules
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Historical review of pharmacological development and dosimetry of PSMA-based theranostics for prostate cancer
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Metamorphosis of prostate specific membrane antigen (PSMA) inhibitors
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Glutamate carboxypeptidase II
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Autoradiography on deparaffinized tissue sections – A feasibility study with 68Ga-labeled PET-tracers
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Design, synthesis, and evaluation of 5-methyl-4-phenoxy-5H-pyrrolo[3,2-d]pyrimidine derivatives: Novel VEGFR2 kinase inhibitors binding to inactive kinase conformation
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A targeted low molecular weight near-infrared fluorescent probe for prostate cancer
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Spacer length effects on in vitro imaging and surface accessibility of fluorescent inhibitors of prostate specific membrane antigen
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Targeting prostate cancer cells with a multivalent PSMA inhibitor-guided streptavidin conjugate
inferred← citeshttps://doi.org/10.1016/j.bmcl.2012.11.015openalex-snapshot
Targeting prostate cancer cells with PSMA inhibitor-guided gold nanoparticles
inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.04.047openalex-snapshot
Synthesis and evaluation of constrained phosphoramidate inhibitors of prostate-specific membrane antigen
inferred← citeshttps://doi.org/10.1016/j.bmcl.2023.129573openalex-snapshot
PSMA-targeted small-molecule drug-conjugates with valine-citrulline and phosphoramidate cleavable linkers
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129657openalex-snapshot
PSMA-targeted SMART molecules outfitted with SN38
inferred← citeshttps://doi.org/10.1016/j.bmcl.2024.129712openalex-snapshot
A PSMA-targeted doxorubicin small-molecule drug conjugate
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Prostate-specific membrane antigen-targeted photodynamic therapy induces rapid cytoskeletal disruption
inferred← citeshttps://doi.org/10.1016/j.ejmech.2021.113502openalex-snapshot
Synthesis and preclinical evaluation of an Al18F radiofluorinated bivalent PSMA ligand
inferred← citeshttps://doi.org/10.1016/j.nucmedbio.2015.06.003openalex-snapshot
A high-affinity [18F]-labeled phosphoramidate peptidomimetic PSMA-targeted inhibitor for PET imaging of prostate cancer
inferred← citeshttps://doi.org/10.1016/j.ymeth.2017.06.026openalex-snapshot
PSMA ligands in prostate cancer – Probe optimization and theranostic applications
inferred← citeshttps://doi.org/10.1021/acs.bioconjchem.1c00435openalex-snapshot
Prostate-Specific Membrane Antigen-Targeted Turn-on Probe for Imaging Cargo Release in Prostate Cancer Cells
inferred← citeshttps://doi.org/10.1021/acs.jcim.3c01542openalex-snapshot
Structural, Biochemical, and Computational Characterization of Sulfamides as Bimetallic Peptidase Inhibitors
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b01806openalex-snapshot
Unprecedented Binding Mode of Hydroxamate-Based Inhibitors of Glutamate Carboxypeptidase II: Structural Characterization and Biological Activity
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5b01850openalex-snapshot
Structure–Activity Relationship of 18F-Labeled Phosphoramidate Peptidomimetic Prostate-Specific Membrane Antigen (PSMA)-Targeted Inhibitor Analogues for PET Imaging of Prostate Cancer
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.9b02022openalex-snapshot
Novel β- and γ-Amino Acid-Derived Inhibitors of Prostate-Specific Membrane Antigen
inferred← citeshttps://doi.org/10.1021/acscatal.8b05051openalex-snapshot
Covalent Inhibition Mechanism of Antidiabetic Drugs—Vildagliptin vs Saxagliptin
inferred← citeshttps://doi.org/10.1021/acsomega.8b00790openalex-snapshot
Effect of Carbohydration on the Theranostic Tracer PSMA I&T
inferred← citeshttps://doi.org/10.1021/bc200279bopenalex-snapshot
68 Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging
inferred← citeshttps://doi.org/10.1021/bc500362nopenalex-snapshot
Development of Inhibitor-Directed Enzyme Prodrug Therapy (IDEPT) for Prostate Cancer
inferred← citeshttps://doi.org/10.1021/jm200807mopenalex-snapshot
Novel Substrate-Based Inhibitors of Human Glutamate Carboxypeptidase II with Enhanced Lipophilicity
inferred← citeshttps://doi.org/10.1021/jm3009822openalex-snapshot
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inferred← citeshttps://doi.org/10.1038/s41598-021-98555-yopenalex-snapshot
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inferred← citeshttps://doi.org/10.1039/9781837677139-00278openalex-snapshot
Prostate-specific Membrane Antigen Targeted Prostate Imaging and Therapy
inferred← citeshttps://doi.org/10.1039/c4ra01454eopenalex-snapshot
The diverse pharmacology and medicinal chemistry of phosphoramidates – a review
inferred← citeshttps://doi.org/10.1039/d4cp04137bopenalex-snapshot
Balancing enthalpy and entropy in inhibitor binding to the prostate-specific membrane antigen (PSMA)
inferred← citeshttps://doi.org/10.1111/cbdd.12174openalex-snapshot
Rationally Designed Sulfamides as Glutamate Carboxypeptidase II Inhibitors
inferred← citeshttps://doi.org/10.1111/febs.13557openalex-snapshot
Design of composite inhibitors targeting glutamate carboxypeptidase II : the importance of effector functionalities
inferred← citeshttps://doi.org/10.1158/1078-0432.ccr-15-0820openalex-snapshot
New Strategies in Prostate Cancer: Prostate-Specific Membrane Antigen (PSMA) Ligands for Diagnosis and Therapy
inferred← citeshttps://doi.org/10.1186/2191-219x-2-23openalex-snapshot
A dimerized urea-based inhibitor of the prostate-specific membrane antigen for 68Ga-PET imaging of prostate cancer
inferred← citeshttps://doi.org/10.1186/s13550-018-0382-8openalex-snapshot
Synthesis and preclinical evaluation of novel 18F-labeled Glu-urea-Glu-based PSMA inhibitors for prostate cancer imaging: a comparison with 18F-DCFPyl and 18F-PSMA-1007
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Paving the way for future PSMA inhibitors: insights from comparative preclinical evaluations of structure modifications
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(R)-NODAGA-PSMA: A Versatile Precursor for Radiometal Labeling and Nuclear Imaging of PSMA-Positive Tumors
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Prostate-Specific Membrane Antigen and Esterase Dual Responsive Camptothecin–Oligopeptide Self-Assembled Nanoparticles for Efficient Anticancer Drug Delivery
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Glutamate Carboxypeptidase II in Diagnosis and Treatment of Neurologic Disorders and Prostate Cancer
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Assessment of an 18F-Labeled Phosphoramidate Peptidomimetic as a New Prostate-Specific Membrane Antigen–Targeted Imaging Agent for Prostate Cancer
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Pharmacokinetic Properties of Peptidic Radiopharmaceuticals: Reduced Uptake of (EH)3-Conjugates in Important Organs
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Optimization of Labeling PSMAHBED with Ethanol-Postprocessed 68Ga and Its Quality Control Systems
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Preclinical Evaluation of 18 F-PSMA-1007, a New Prostate-Specific Membrane Antigen Ligand for Prostate Cancer Imaging
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Bioconjugation of therapeutic proteins and enzymes using the expanded set of genetically encoded amino acids
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Refined Chelator Spacer Moieties Ameliorate the Pharmacokinetics of PSMA-617
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Repurposing of PSMA-targeted diagnostic and therapeutic agents for the detection and treatment of giant cell tumors of bone
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Synthesis and Evaluation of 99mTc-Tricabonyl Labeled Isonitrile Conjugates for Prostate-Specific Membrane Antigen (PSMA) Image
inferred← citeshttps://doi.org/10.3390/molecules22040523openalex-snapshot
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inferred← citeshttps://doi.org/10.3390/nu10111644openalex-snapshot
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