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Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture

https://doi.org/10.1021/cb300189b
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A novel strategy to design latent ratiometric fluorescent pH probes based on self-assembled SNARF derivatives
inferred← citeshttps://doi.org/10.1039/c5cp01980jopenalex-snapshot
Investigating the molecular and aggregated states of a drug molecule rutaecarpine using spectroscopy, microscopy, crystallography and computational studies
inferred← citeshttps://doi.org/10.1039/c5ob00239gopenalex-snapshot
Binding-induced, turn-on fluorescence of the EGFR/ERBB kinase inhibitor, lapatinib
inferred← citeshttps://doi.org/10.1039/c9ra06466dopenalex-snapshot
Resonant waveguide grating based assays for colloidal aggregate detection and promiscuity characterization in natural products
inferred← citeshttps://doi.org/10.1039/d0cb00219dopenalex-snapshot
Biological functions of supramolecular assemblies of small molecules in the cellular environment
inferred← citeshttps://doi.org/10.1063/5.0021834openalex-snapshot
Relationship between bio-effects and energy transduction during nanoparticle-mediated photoporation
inferred← citeshttps://doi.org/10.1063/5.0052537openalex-snapshot
Cyclodextrin solubilization in hydrated reline: Resolving the unique stabilization mechanism in a deep eutectic solvent
inferred← citeshttps://doi.org/10.1080/17460913.2025.2525717openalex-snapshot
Employing machine learning for identifying antifungal compounds against Candida albicans
inferred← citeshttps://doi.org/10.1089/adt.2010.0805.lropenalex-snapshot
Literature Search and Review
inferred← citeshttps://doi.org/10.1089/adt.2012.1006.lropenalex-snapshot
Literature Search and Review
inferred← citeshttps://doi.org/10.1089/can.2020.0115openalex-snapshot
Regarding the Mechanisms of Promiscuous Cannabinoid Pharmacology: An Elephant Has Entered the Room
inferred← citeshttps://doi.org/10.1093/bib/bbaf205openalex-snapshot
Advancing promiscuous aggregating inhibitor analysis with intelligent machine learning classification
inferred← citeshttps://doi.org/10.1101/2020.03.22.002543openalex-snapshot
Three Essential Resources to Improve Differential Scanning Fluorimetry (DSF) Experiments
inferred← citeshttps://doi.org/10.1101/2022.07.25.501379openalex-snapshot
Enhanced surface nano-analytics of transient biomolecular processes
inferred← citeshttps://doi.org/10.1101/2022.09.29.509997openalex-snapshot
An mTOR-independent Macroautophagy Activator Ameliorates Tauopathy and Prionopathy Neurodegeneration Phenotypes
inferred← citeshttps://doi.org/10.1111/cote.12093openalex-snapshot
Where do dyes go inside living cells? Predicting uptake, intracellular localisation, and accumulation using QSAR models
inferred← citeshttps://doi.org/10.1111/micc.12228openalex-snapshot
A Retrospective 30 Years After Discovery of the Enhanced Permeability and Retention Effect of Solid Tumors: Next‐Generation Chemotherapeutics and Photodynamic Therapy—Problems, Solutions, and Prospects
inferred← citeshttps://doi.org/10.1126/sciadv.abq3151openalex-snapshot
Enhanced surface nanoanalytics of transient biomolecular processes
inferred← citeshttps://doi.org/10.1128/aac.00300-21openalex-snapshot
RNase P Inhibitors Identified as Aggregators
inferred← citeshttps://doi.org/10.1177/2472555217732014openalex-snapshot
A High-Throughput Dose-Response Cellular Thermal Shift Assay for Rapid Screening of Drug Target Engagement in Living Cells, Exemplified Using SMYD3 and IDO1
inferred← citeshttps://doi.org/10.1371/journal.pcbi.1007025openalex-snapshot
Deep Learning-driven research for drug discovery: Tackling Malaria
inferred← citeshttps://doi.org/10.1371/journal.pone.0053499openalex-snapshot
Interaction of Multimicrobial Synthetic Inhibitor 1,2-Bis(2-Benzimidazolyl)-1,2-Ethanediol with Serum Albumin: Spectroscopic and Computational Studies
inferred← citeshttps://doi.org/10.1371/journal.pone.0069394openalex-snapshot
Transport Inhibition of Digoxin Using Several Common P-gp Expressing Cell Lines Is Not Necessarily Reporting Only on Inhibitor Binding to P-gp
inferred← citeshttps://doi.org/10.1371/journal.pone.0140006openalex-snapshot
Investigating Apoptozole as a Chemical Probe for HSP70 Inhibition
inferred← citeshttps://doi.org/10.1371/journal.pone.0150602openalex-snapshot
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
inferred← citeshttps://doi.org/10.1515/ntrev-2016-0071openalex-snapshot
Biomaterial-based nanoreactors, an alternative for enzyme delivery
inferred← citeshttps://doi.org/10.1517/17460441.2016.1128892openalex-snapshot
Non-stoichiometric inhibition in integrated lead finding – a literature review
inferred← citeshttps://doi.org/10.1530/ec-23-0178openalex-snapshot
A method to detect fulvestrant interference in estradiol in breast cancer patients
inferred← citeshttps://doi.org/10.17615/da0x-y275openalex-snapshot
Evolution and Prevention of Antibiotic Resistance: Small Molecule Inhibitors of Bacterial Recombination Enzymes
inferred← citeshttps://doi.org/10.3109/10520295.2013.780634openalex-snapshot
Predicting small molecule fluorescent probe localization in living cells using QSAR modeling. 1. Overview and models for probes of structure, properties and function in single cells
inferred← citeshttps://doi.org/10.3389/fchem.2014.00050openalex-snapshot
Human isoprenoid synthase enzymes as therapeutic targets
inferred← citeshttps://doi.org/10.3389/fphar.2022.909945openalex-snapshot
Polyphenolic promiscuity, inflammation-coupled selectivity: Whether PAINs filters mask an antiviral asset
inferred← citeshttps://doi.org/10.3390/antibiotics9090633openalex-snapshot
Repurposing Disulfiram (Tetraethylthiuram Disulfide) as a Potential Drug Candidate against Borrelia burgdorferi In Vitro and In Vivo
inferred← citeshttps://doi.org/10.3390/antiox11020280openalex-snapshot
Hydroxamic Acid as a Potent Metal-Binding Group for Inhibiting Tyrosinase
inferred← citeshttps://doi.org/10.3390/antiox9020126openalex-snapshot
The Astaxanthin Aggregation Pattern Greatly Influences Its Antioxidant Activity: A Comparative Study in Caco-2 Cells
inferred← citeshttps://doi.org/10.3390/biom10040605openalex-snapshot
Sorafenib as an Inhibitor of RUVBL2
inferred← citeshttps://doi.org/10.3390/cells8111462openalex-snapshot
Recent Advances in EPAC-Targeted Therapies: A Biophysical Perspective
inferred← citeshttps://doi.org/10.3390/ijms21228709openalex-snapshot
Discovery and Design of Novel Small Molecule GSK-3 Inhibitors Targeting the Substrate Binding Site
inferred← citeshttps://doi.org/10.3390/ijms25010269openalex-snapshot
The Potential of Congo Red Supplied Aggregates of Multitargeted Tyrosine Kinase Inhibitor (Sorafenib, BAY-43-9006) in Enhancing Therapeutic Impact on Bladder Cancer
inferred← citeshttps://doi.org/10.3390/ijms26041429openalex-snapshot
Combining Sulfonylureas with Anticancer Drugs: Evidence of Synergistic Efficacy with Doxorubicin In Vitro and In Vivo
inferred← citeshttps://doi.org/10.3390/ma14216231openalex-snapshot
Advances Brought by Hydrophilic Ionic Liquids in Fields Involving Pharmaceuticals
inferred← citeshttps://doi.org/10.3390/molecules25204723openalex-snapshot
Merging Ligand-Based and Structure-Based Methods in Drug Discovery: An Overview of Combined Virtual Screening Approaches
inferred← citeshttps://doi.org/10.3390/ph15020236openalex-snapshot
Discovery of Kinase and Carbonic Anhydrase Dual Inhibitors by Machine Learning Classification and Experiments
inferred← citeshttps://doi.org/10.3390/pharmaceutics13111829openalex-snapshot
Targeting Engineered Nanoparticles for Breast Cancer Therapy
inferred← citeshttps://doi.org/10.3390/v7122933openalex-snapshot
Natural Products as Tools for Defining How Cellular Metabolism Influences Cellular Immune and Inflammatory Function during Chronic Infection
inferred← citeshttps://doi.org/10.34297/ajbsr.2019.05.000970openalex-snapshot
Nanocarrier Applied in The Distribution of Drugs in the Assistance for the Cancer Treatment
inferred← citeshttps://doi.org/10.4155/tde.15.45openalex-snapshot
Intestinal Solubility and Absorption of Poorly Water Soluble compounds: predictions, Challenges and Solutions
inferred← citeshttps://doi.org/10.64898/2026.01.28.701823openalex-snapshot
A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture
inferred← citeshttps://doi.org/10.70675/d535d4f6ze297z4e33z965az6b622a16f280openalex-snapshot
Diversité chimique et potentialités antivirales d'Euphorbiacées tropicales
inferred← citeshttps://doi.org/10.7270/q2j38tw7openalex-snapshot
BindingDB Entry 50042550: Colloidal aggregation causes inhibition of G protein-coupled receptors.
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