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Resonant waveguide grating based assays for colloidal aggregate detection and promiscuity characterization in natural products

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/j.biotechadv.2015.08.001openalex-snapshot

Discovery and resupply of pharmacologically active plant-derived natural products: A review

inferredcites →https://doi.org/10.1016/j.cbpa.2010.03.020openalex-snapshot

Apparent activity in high-throughput screening: origins of compound-dependent assay interference

inferredcites →https://doi.org/10.1016/j.phymed.2010.02.002openalex-snapshot

Rosenroot (Rhodiola rosea): Traditional use, chemical composition, pharmacology and clinical efficacy

inferredcites →https://doi.org/10.1016/j.vascn.2006.11.001openalex-snapshot

Non-invasive optical biosensor for assaying endogenous G protein-coupled receptors in adherent cells

inferredcites →https://doi.org/10.1021/ac050887nopenalex-snapshot

Characteristics of Dynamic Mass Redistribution of Epidermal Growth Factor Receptor Signaling in Living Cells Measured with Label-Free Optical Biosensors

inferredcites →https://doi.org/10.1021/ac301495nopenalex-snapshot

Probing Biochemical Mechanisms of Action of Muscarinic M3 Receptor Antagonists with Label-Free Whole Cell Assays

inferredcites →https://doi.org/10.1021/acs.jmedchem.5b01009openalex-snapshot

Can Invalid Bioactives Undermine Natural Product-Based Drug Discovery?

inferredcites →https://doi.org/10.1021/acs.jmedchem.6b01836openalex-snapshot

Structural Basis of Small-Molecule Aggregate Induced Inhibition of a Protein–Protein Interaction

inferredcites →https://doi.org/10.1021/acs.jnatprod.5b00947openalex-snapshot

Feeling Nature’s PAINS: Natural Products, Natural Product Drugs, and Pan Assay Interference Compounds (PAINS)

inferredcites →https://doi.org/10.1021/acsmedchemlett.5b00032openalex-snapshot

Screening-Based Translation of Public Research Encounters Painful Problems

inferredcites →https://doi.org/10.1021/cb300189bopenalex-snapshot

Colloidal Aggregation Affects the Efficacy of Anticancer Drugs in Cell Culture

inferredcites →https://doi.org/10.1021/cb5009487openalex-snapshot

Colloidal Aggregation and the in Vitro Activity of Traditional Chinese Medicines

inferredcites →https://doi.org/10.1021/ja0455547openalex-snapshot

ALARM NMR: A Rapid and Robust Experimental Method To Detect Reactive False Positives in Biochemical Screens

inferredcites →https://doi.org/10.1021/ja802977hopenalex-snapshot

Stoichiometry and Physical Chemistry of Promiscuous Aggregate-Based Inhibitors

inferredcites →https://doi.org/10.1021/jm010533yopenalex-snapshot

A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

inferredcites →https://doi.org/10.1021/jm030191ropenalex-snapshot

Identification and Prediction of Promiscuous Aggregating Inhibitors among Known Drugs

inferredcites →https://doi.org/10.1021/jm030266ropenalex-snapshot

A Specific Mechanism of Nonspecific Inhibition

inferredcites →https://doi.org/10.1021/jm0340896openalex-snapshot

Effect of Detergent on “Promiscuous” Inhibitors

inferredcites →https://doi.org/10.1021/jm061317yopenalex-snapshot

A High-Throughput Screen for Aggregation-Based Inhibition in a Large Compound Library

inferredcites →https://doi.org/10.1021/jm301008nopenalex-snapshot

Rules for Identifying Potentially Reactive or Promiscuous Compounds

inferredcites →https://doi.org/10.1021/jm301749yopenalex-snapshot

Colloidal Aggregation Causes Inhibition of G Protein-Coupled Receptors

inferredcites →https://doi.org/10.1021/jm400535bopenalex-snapshot

Compound Aggregation in Drug Discovery: Implementing a Practical NMR Assay for Medicinal Chemists

inferredcites →https://doi.org/10.1021/jm4008714openalex-snapshot

Monitoring Drug Self-Aggregation and Potential for Promiscuity in Off-Target In Vitro Pharmacology Screens by a Practical NMR Strategy

inferredcites →https://doi.org/10.1021/jm701301mopenalex-snapshot

Fluorescence Spectroscopic Profiling of Compound Libraries

inferredcites →https://doi.org/10.1021/jm701302vopenalex-snapshot

Characterization of Chemical Libraries for Luciferase Inhibitory Activity

inferredcites →https://doi.org/10.1021/jm801605ropenalex-snapshot

Promiscuous Aggregate-Based Inhibitors Promote Enzyme Unfolding

inferredcites →https://doi.org/10.1038/513481aopenalex-snapshot

Chemistry: Chemical con artists foil drug discovery

inferredcites →https://doi.org/10.1038/nchembio718openalex-snapshot

High-throughput assays for promiscuous inhibitors

inferredcites →https://doi.org/10.1038/nprot.2006.77openalex-snapshot

A detergent-based assay for the detection of promiscuous inhibitors

inferredcites →https://doi.org/10.1038/nprot.2011.386openalex-snapshot

Applying label-free dynamic mass redistribution technology to frame signaling of G protein–coupled receptors noninvasively in living cells

inferredcites →https://doi.org/10.1038/nrd3368openalex-snapshot

Impact of high-throughput screening in biomedical research

inferredcites →https://doi.org/10.1038/nrd4510openalex-snapshot

The re-emergence of natural products for drug discovery in the genomics era

inferredcites →https://doi.org/10.1039/c3np70052fopenalex-snapshot

Matching the power of high throughput screening to the chemical diversity of natural products

inferredcites →https://doi.org/10.1063/1.3522894openalex-snapshot

Resonant waveguide grating imager for live cell sensing

inferredcites →https://doi.org/10.1063/1.4866460openalex-snapshot

Bulk and surface sensitivity of a resonant waveguide grating imager

inferredcites →https://doi.org/10.1081/dmr-200028812openalex-snapshot

Drug Bioactivation Covalent Binding to Target Proteins and Toxicity Relevance

inferredcites →https://doi.org/10.1089/adt.2006.4.583openalex-snapshot

Label-Free Cell-Based Assays with Optical Biosensors in Drug Discovery

inferredcites →https://doi.org/10.1177/1087057109341768openalex-snapshot

Assay Development and Screening of a Serine/Threonine Kinase in an On-Chip Mode Using Caliper Nanofluidics Technology

inferredcites →https://doi.org/10.1529/biophysj.105.077818openalex-snapshot

Resonant Waveguide Grating Biosensor for Living Cell Sensing

inferredcites →https://doi.org/10.2174/092986710793348545openalex-snapshot

False Positives in the Early Stages of Drug Discovery

inferredcites →https://doi.org/10.2174/138620708784534789openalex-snapshot

Label-Free Cell-Based Assays for GPCR Screening

inferredcites →https://doi.org/10.2174/157016306778108875openalex-snapshot

NMR-Based Quality Control Approach for the Identification of False Positives and False Negatives in High Throughput Screening

inferredcites →https://doi.org/10.3390/molecules170910774openalex-snapshot

Aggregating Behavior of Phenolic Compounds — A Source of False Bioassay Results?

inferredcites →https://doi.org/10.3390/s120709181openalex-snapshot

A Unifying Review of Bioassay-Guided Fractionation, Effect-Directed Analysis and Related Techniques

inferredcites →https://doi.org/10.3390/s7102316openalex-snapshot

Non-invasive Optical Biosensor for Probing Cell Signaling

inferredcites →https://doi.org/10.4155/fmc.12.55openalex-snapshot

Guiding Principles for Natural Product Drug Discovery

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.2139/ssrn.4200195openalex-extracted

Decoloration and Alkaloid Enrichment of Dactylicapnos Scandens Extracts Based on Strong Anion-Exchange Resins in Tandem with Strong Cation-Exchange Silica-Based Materials

inferred← citeshttps://doi.org/10.1016/j.cbi.2022.110199openalex-snapshot

Discovery and characterization of novel ATP citrate lyase inhibitors from natural products by a luminescence-based assay

inferred← citeshttps://doi.org/10.1016/j.cis.2021.102431openalex-snapshot

Data evaluation for surface-sensitive label-free methods to obtain real-time kinetic and structural information of thin films: A practical review with related software packages

inferred← citeshttps://doi.org/10.1016/j.fitote.2024.105956openalex-snapshot

Discovery and characterization of novel ATP citrate lyase inhibitors from Acanthopanax senticosus (Rupr. & Maxim.) Harms

inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e25603openalex-snapshot

Label-free biomolecular and cellular methods in small molecule epigallocatechin-gallate research

inferred← citeshttps://doi.org/10.1016/j.jchromb.2023.123637openalex-snapshot

Decoloration and alkaloid enrichment of Dactylicapnos scandens extracts based on the use of strong anion-exchange resins in tandem with strong cation-exchange silica-based materials

inferred← citeshttps://doi.org/10.1016/j.jcis.2021.04.091openalex-snapshot

Label-free tracking of whole-cell response on RGD functionalized surfaces to varied flow velocities generated by fluidic rotation

inferred← citeshttps://doi.org/10.1093/bib/bbaf205openalex-snapshot

Advancing promiscuous aggregating inhibitor analysis with intelligent machine learning classification

inferred← citeshttps://doi.org/10.3390/biomedicines9121781openalex-snapshot

Natural Compounds as Target Biomolecules in Cellular Adhesion and Migration: From Biomolecular Stimulation to Label-Free Discovery and Bioactivity-Based Isolation

inferred← citeshttps://doi.org/10.3390/ijms231810747openalex-snapshot

Discovery of Flavonoids as Novel Inhibitors of ATP Citrate Lyase: Structure–Activity Relationship and Inhibition Profiles

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