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Pharmaceutical Crystallization

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Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/(sici)1520-6017(200004)89:4<478::aid-jps5>3.0.co;2-5openalex-snapshot
Structure and Solid‐State Chemistry of Anhydrous and Hydrated Crystal forms of the Trimethoprim‐Sulfamethoxypyridazine 1:1 Molecular Complex
inferredcites →https://doi.org/10.1002/1520-6017(200103)90:3<371::aid-jps12>3.0.co;2-nopenalex-snapshot
Conformational Color Polymorphism and Control of Crystallization of 5‐Methyl‐2‐[(4‐methyl‐2‐nitrophenyl)amino]‐3‐thiophenecarbonitrile
inferredcites →https://doi.org/10.1002/3527607889openalex-snapshot
Polymorphism
inferredcites →https://doi.org/10.1002/jps.20949openalex-snapshot
Efficient Co-crystal Screening Using Solution-Mediated Phase Transformation
inferredcites →https://doi.org/10.1002/jps.21942openalex-snapshot
Manufacture of pharmaceutical co‐crystals using twin screw extrusion: A solvent‐less and scalable process
inferredcites →https://doi.org/10.1007/bf01197379openalex-snapshot
On the polymorphism of pharmaceuticals and other molecular crystals. I
inferredcites →https://doi.org/10.1007/bf01197380openalex-snapshot
On the polymorphism of pharmaceuticals and other molecular crystals. II
inferredcites →https://doi.org/10.1007/s11095-006-9032-3openalex-snapshot
Use of a Glutaric Acid Cocrystal to Improve Oral Bioavailability of a Low Solubility API
inferredcites →https://doi.org/10.1007/s11705-009-0294-2openalex-snapshot
Polymorphism of pharmaceutical molecules: perspectives on nucleation
inferredcites →https://doi.org/10.1016/0021-9797(72)90185-3openalex-snapshot
Theory of particulate processes-analysis and techniques of continuous crystallization
inferredcites →https://doi.org/10.1016/b978-0-7506-7012-8.x5000-9openalex-snapshot
Handbook of Industrial Crystallization
inferredcites →https://doi.org/10.1016/j.addr.2003.10.008openalex-snapshot
Drug polymorphism and dosage form design: a practical perspective
inferredcites →https://doi.org/10.1016/j.addr.2003.10.020openalex-snapshot
High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids
inferredcites →https://doi.org/10.1016/j.ejpb.2006.12.016openalex-snapshot
Performance comparison of a co-crystal of carbamazepine with marketed product
inferredcites →https://doi.org/10.1016/j.ejps.2009.05.010openalex-snapshot
Formation of indomethacin–saccharin cocrystals using supercritical fluid technology
inferredcites →https://doi.org/10.1016/j.jcrysgro.2009.02.040openalex-snapshot
Formation of co-crystals: Kinetic and thermodynamic aspects
inferredcites →https://doi.org/10.1016/j.jssc.2007.06.033openalex-snapshot
Continuous nanoparticle production by microfluidic-based emulsion, mixing and crystallization
inferredcites →https://doi.org/10.1016/s0022-0248(99)00181-5openalex-snapshot
The initial stage of crystallization of lysozyme: a differential scanning calorimetric (DSC) study
inferredcites →https://doi.org/10.1021/ar00172a005openalex-snapshot
Encoding and decoding hydrogen-bond patterns of organic compounds
inferredcites →https://doi.org/10.1021/cen-v085n025.p017openalex-snapshot
FORM AND FUNCTION
inferredcites →https://doi.org/10.1021/cg049646jopenalex-snapshot
Influence of Impurities on the Solution-Mediated Phase Transformation of an Active Pharmaceutical Ingredient
inferredcites →https://doi.org/10.1021/cg0496540openalex-snapshot
Pharmaceutical Cocrystallization: Engineering a Remedy for Caffeine Hydration
inferredcites →https://doi.org/10.1021/cg0497344openalex-snapshot
SAXS Study of the Nucleation of Glycine Crystals from a Supersaturated Solution
inferredcites →https://doi.org/10.1021/cg050125lopenalex-snapshot
Saccharin Salts of Active Pharmaceutical Ingredients, Their Crystal Structures, and Increased Water Solubilities
inferredcites →https://doi.org/10.1021/cg060885bopenalex-snapshot
Toward Rational Design of Tailor-made Additives Using Growth Site Statistics
inferredcites →https://doi.org/10.1021/cg070218yopenalex-snapshot
Making Co-CrystalsThe Utility of Ternary Phase Diagrams
inferredcites →https://doi.org/10.1021/cg100198uopenalex-snapshot
Operating Regions in Cooling Cocrystallization of Caffeine and Glutaric Acid in Acetonitrile
inferredcites →https://doi.org/10.1021/cg100514gopenalex-snapshot
Supramolecular Architectures of Meloxicam Carboxylic Acid Cocrystals, a Crystal Engineering Case Study
inferredcites →https://doi.org/10.1021/cg800095zopenalex-snapshot
Modeling and Computational Fluid Dynamics−Population Balance Equation−Micromixing Simulation of Impinging Jet Crystallizers
inferredcites →https://doi.org/10.1021/cg8005019openalex-snapshot
Drug Substance and Former Structure Property Relationships in 15 Diverse Pharmaceutical Co-Crystals
inferredcites →https://doi.org/10.1021/cg800934hopenalex-snapshot
Design and Optimization of a Combined Cooling/Antisolvent Crystallization Process
inferredcites →https://doi.org/10.1021/cg801019dopenalex-snapshot
Cocrystal Formation in Solution: In Situ Solute Concentration Monitoring of the Two Components and Kinetic Pathways
inferredcites →https://doi.org/10.1021/cg801039jopenalex-snapshot
Solubility Advantage of Pharmaceutical Cocrystals
inferredcites →https://doi.org/10.1021/cg801145copenalex-snapshot
Synthon Competition and Cooperation in Molecular Salts of Hydroxybenzoic Acids and Aminopyridines
inferredcites →https://doi.org/10.1021/cg900554hopenalex-snapshot
Indo−U.S. Workshop on Pharmaceutical Cocrystals and Polymorphs
inferredcites →https://doi.org/10.1021/cg901496sopenalex-snapshot
Continuous Plug Flow Crystallization of Pharmaceutical Compounds
inferredcites →https://doi.org/10.1021/j100165a007openalex-snapshot
Hydrogen bonds as design elements in organic chemistry
inferredcites →https://doi.org/10.1021/ja00297a017openalex-snapshot
Crystal morphology engineering by "tailor-made" inhibitors; a new probe to fine intermolecular interactions
inferredcites →https://doi.org/10.1021/ja035776popenalex-snapshot
Crystal Engineering of Novel Cocrystals of a Triazole Drug with 1,4-Dicarboxylic Acids
inferredcites →https://doi.org/10.1021/ja048114oopenalex-snapshot
Crystal Engineering Approach To Forming Cocrystals of Amine Hydrochlorides with Organic Acids. Molecular Complexes of Fluoxetine Hydrochloride with Benzoic, Succinic, and Fumaric Acids
inferredcites →https://doi.org/10.1021/ja9626345openalex-snapshot
Polymorphism in Molecular Crystals: Stabilization of a Metastable Form by Conformational Mimicry
inferredcites →https://doi.org/10.1021/mp050099mopenalex-snapshot
Reaction Crystallization of Pharmaceutical Molecular Complexes
inferredcites →https://doi.org/10.1021/op000023yopenalex-snapshot
Dealing with the Impact of Ritonavir Polymorphs on the Late Stages of Bulk Drug Process Development
inferredcites →https://doi.org/10.1021/op0499268openalex-snapshot
Polymorphism and Impurities
inferredcites →https://doi.org/10.1021/op100115uopenalex-snapshot
Process Research and Development of a MTP Inhibitor: Another Case of Disappearing Polymorphs upon Scale-up
inferredcites →https://doi.org/10.1021/op900237xopenalex-snapshot
Continuous Crystallization of Pharmaceuticals Using a Continuous Oscillatory Baffled Crystallizer
inferredcites →https://doi.org/10.1039/b202063gopenalex-snapshot
Ten years of experience in polymorph prediction: what next?
inferredcites →https://doi.org/10.1039/b402150aopenalex-snapshot
Crystal engineering of the composition of pharmaceutical phases. Do pharmaceutical co-crystals represent a new path to improved medicines?
inferredcites →https://doi.org/10.1039/b501304fopenalex-snapshot
Crystal engineering of pharmaceutical co-crystals from polymorphic active pharmaceutical ingredients
inferredcites →https://doi.org/10.1039/b715396aopenalex-snapshot
Screening strategies based on solubility and solution composition generate pharmaceutically acceptable cocrystals of carbamazepine
inferredcites →https://doi.org/10.1039/b813058bopenalex-snapshot
Scalable solution cocrystallization: case of carbamazepine-nicotinamide I
inferredcites →https://doi.org/10.1063/1.3548889openalex-snapshot
A general set of order parameters for molecular crystals
inferredcites →https://doi.org/10.1063/1.443932openalex-snapshot
A comparison of measured nucleation rates with the predictions of several theories of homogeneous nucleation
inferredcites →https://doi.org/10.1073/pnas.122055299openalex-snapshot
Liquid–liquid separation in solutions of normal and sickle cell hemoglobin
inferredcites →https://doi.org/10.1093/oso/9780199655441.001.0001openalex-snapshot
Polymorphism in Molecular Crystals
inferredcites →https://doi.org/10.1103/physrevlett.89.175501openalex-snapshot
Polarization Switching of Crystal Structure in the Nonphotochemical Light-Induced Nucleation of Supersaturated Aqueous Glycine Solutions
inferredcites →https://doi.org/10.1103/physrevlett.94.235703openalex-snapshot
Interplay between Structure and Size in a Critical Crystal Nucleus
inferredcites →https://doi.org/10.1107/s0907444997006847openalex-snapshot
Lysozyme Aggregation Studied by Light Scattering. I. Influence of Concentration and Nature of Electrolytes
inferredcites →https://doi.org/10.1107/s0907444997006859openalex-snapshot
Lysozyme Aggregation Studied by Light Scattering. II. Variations of Protein Concentration
inferredcites →https://doi.org/10.1126/science.277.5334.1975openalex-snapshot
Enhancement of Protein Crystal Nucleation by Critical Density Fluctuations
inferredcites →https://doi.org/10.1515/zpch-1897-2233openalex-snapshot
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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Continuous Crystallisation
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Droplet‐Templated Antisolvent Spherical Crystallization of Hydrophilic and Hydrophobic Drugs with an in situ Formed Binder
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Hydrogel Microparticle‐Templated Anti‐Solvent Crystallization of Small‐Molecule Drugs
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A Novel Acoustomicrofluidic Nebulization Technique Yielding New Crystallization Morphologies
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Real‐Space Crystal Structure Analysis by Low‐Dose Focal‐Series TEM Imaging of Organic Materials with Near‐Atomic Resolution
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Semireduction of Secondary Aryl Amides to Imines Using a Mixed Aluminum Hydride Reagent
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Fines removal in a continuous plug flow crystallizer by optimal spatial temperature profiles with controlled dissolution
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Continuous manufacturing: Is the process mean stationary?
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Interfacial microdroplet evaporative crystallization on 3D printed regular matrix platform
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The axial dispersion of liquid solutions and solid suspensions in planar oscillatory flow crystallizers
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Form selection of concomitant polymorphs: A case study informed by crystallization kinetics modeling
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Mechanism and kinetic modeling study on the crystallization of concomitant polymorphs
inferred← citeshttps://doi.org/10.1002/amp2.10150openalex-snapshot
Advanced pharmaceutical manufacturing: A functional definition
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End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation
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Flüssige metastabile Vorstufen von Ibuprofen als Zwischenprodukt der Nukleation in wässriger Lösung
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Two‐Step Crystal Dissolution: A Molecular Mechanism to Rationalize Empiric Models of Drug Release from API Formulations for Oral Administration
inferred← citeshttps://doi.org/10.1002/anie.201305429openalex-snapshot
End‐to‐End Continuous Manufacturing of Pharmaceuticals: Integrated Synthesis, Purification, and Final Dosage Formation
inferred← citeshttps://doi.org/10.1002/anie.201910986openalex-snapshot
Liquid Metastable Precursors of Ibuprofen as Aqueous Nucleation Intermediates
inferred← citeshttps://doi.org/10.1002/anie.202507827openalex-snapshot
Two‐Step Crystal Dissolution: A Molecular Mechanism to Rationalize Empiric Models of Drug Release from API Formulations for Oral Administration
inferred← citeshttps://doi.org/10.1002/ceat.201600072openalex-snapshot
Design of a Continuous Tubular Cooling Crystallizer for Process Development on Lab‐Scale
inferred← citeshttps://doi.org/10.1002/ceat.201700657openalex-snapshot
Continuous Downstream Processing of Amino Acids in a Modular Miniplant
inferred← citeshttps://doi.org/10.1002/ceat.202100574openalex-snapshot
Ultrasound‐Assisted Slug‐Flow Tubular Crystallization for Preparation of Fine Ibuprofen Crystals
inferred← citeshttps://doi.org/10.1002/ceat.202300314openalex-snapshot
A Comprehensive Workflow towards More Equant‐Shaped Crystals of Active Pharmaceutical Ingredients
inferred← citeshttps://doi.org/10.1002/chem.201103669openalex-snapshot
Confused HCl: Hydrogen Chloride or Hydrochloric Acid?
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Translating Solid‐Phase Conformational Memory in the Prophecy of Multi‐stimuli Responsive Low Molecular Weight Gels
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Betriebsbereich und Auslegung von Rohrapparaten für die kontinuierliche Kristallisation
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Use of a Scattered Light Sensor for Monitoring the Dispersed Surface in Crystallization
inferred← citeshttps://doi.org/10.1002/crat.201300288openalex-snapshot
Evaluation of nucleation rate by in‐situ focused beam reflectance measurement in an unseeded batch cooling crystallization
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The Potential of Cucurbit[n]urils in Drug Delivery
inferred← citeshttps://doi.org/10.1002/jctb.7497openalex-snapshot
Application of PAT in pharmaceutical manufacturing: model‐based control of particle size distribution in anti‐solvent aided crystallization
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Ultrasound‐assisted improved crystallization of dimethyl sulphone
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The Future of Pharmaceutical Manufacturing Sciences
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Supramolecular Metal–Phenolic Gels for the Crystallization of Active Pharmaceutical Ingredients
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3D Controllable Crystallization by Programmable Seeding
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Continuous Crystallization Platforms to Crystallize Biomolecules
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Classical and Nonclassical Nucleation Mechanisms of Biomolecules
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Flow as a Control Strategy to Promote Biomolecule Nucleation
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A Deep Learning Approach for Molecular Crystallinity Prediction
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Continuous Crystallization: Equipment and Operation
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Crystal Breakage of Mechanically Labile Protein Crystals in the Field of Mechanical Solid-Liquid Separation
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Crystallization
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Crystal Nucleation of Small Organic Molecules
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Crystallization
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Alternative to Chromatography: Purification of Therapeutic Protein/Peptides by Continuous Crystallization in Millifluidics
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Induction Time of L-Isoleucine Crystallization with the Presence of Electric Field
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Use of a scattered light sensor for monitoring the dispersed surface in multimodal system
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Determination of Solubility and Nucleation Kinetics of Valnemulin Hydrochloride Solvate
inferred← citeshttps://doi.org/10.1007/s10973-019-08455-7openalex-snapshot
Evaluation of crystallization technique relating to the physicochemical properties of cinnamic acid
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Mechanochemical synthesis, characterization and thermal study of new cocrystals of ciprofloxacin with pyrazinoic acid and p-aminobenzoic acid
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Polymorph Formation and Nucleation Mechanism of Tolfenamic Acid in Solution: An Investigation of Pre-nucleation Solute Association
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Exploring Molecular Speciation and Crystallization Mechanism of Amorphous 2-Phenylamino Nicotinic Acid
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Problems, potentials and future of industrial crystallization
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Crystallization of glycine in water/saturated fatty acid emulsions
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Crystallization of the Multi-Receptor Tyrosine Kinase Inhibitor Sorafenib for Controlled Long-Term Drug Delivery Following a Single Injection
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Modernizing Pharmaceutical Manufacturing: from Batch to Continuous Production
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Fast Continuous Non-Seeded Cooling Crystallization of Glycine in Slug Flow: Pure α-Form Crystals with Narrow Size Distribution
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Liquid antisolvent crystallization of pharmaceutical compounds: current status and future perspectives
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Quality by design approach to the development of transdermal patch systems and regulatory perspective
inferred← citeshttps://doi.org/10.1007/s43630-024-00622-6openalex-snapshot
Optical trapping-induced crystallization promoted by gold and silicon nanoparticles
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Alternative Separation Methods: Crystallization and Aqueous Polymer Two-Phase Extraction
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Computer-Aided Molecular Design: Fundamentals, Methods, and Applications
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Emerging Technology for Modernizing Pharmaceutical Production
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Role of Salt Selection in Drug Discovery and Development
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Crystallization: A Tool for Asymmetric Synthesis and Isolation
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Unit operations for extraction and purification of biological products
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Surfacing hybrid medicines of bioactive molecules: a solid states formulation approach
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Supercritical fluids in particle and crystal growth
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Fundamentals of Industrial Crystallization
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Cocrystal Systems of Pharmaceutical Interest: 2012–2014
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Pervaporation-assisted crystallization of active pharmaceutical ingredients (APIs)
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Multi-sensor inline measurements of crystal size and shape distributions during high shear wet milling of crystal slurries
inferred← citeshttps://doi.org/10.1016/j.apt.2020.06.008openalex-snapshot
Development and validation of a two-dimensional population balance model for a supercritical CO2 antisolvent batch crystallization process
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Macrocyclic supramolecular biomaterials in anti-cancer therapeutics
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Online conductivity measurement of residence time distribution of thin film flow in the spinning disc reactor
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Suspension flow behavior and particle residence time distribution in helical tube devices
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A comparative study of continuous operation between a dynamic baffle crystallizer and a stirred tank crystallizer
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Effect of acoustic streaming on continuous flow sonocrystallization in millifluidic channels
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Revealing the effects of microwell sizes on the crystal growth kinetics of active pharmaceutical ingredients by deep learning
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Anti-solvent crystallization: Particle size distribution with different devices
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The role of mixing and surface hydrophobicity on the operation of a continuous tubular slug flow crystalliser for lysozyme
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Continuous crystallization using a sonicated tubular system for controlling particle size in an API manufacturing process
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Evaluation of mixed suspension mixed product removal crystallization processes coupled with a continuous filtration system
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Process intensification for pharmaceutical crystallization
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Characterization of the anti-solvent batch, plug flow and MSMPR crystallization of benzoic acid
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Regions of attainable particle sizes in continuous and batch crystallization processes
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Modeling and control of crystal shape in continuous protein crystallization
inferred← citeshttps://doi.org/10.1016/j.ces.2015.02.014openalex-snapshot
Design and optimization of a multistage continuous cooling mixed suspension, mixed product removal crystallizer
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Kinetic identification and experimental validation of continuous plug flow crystallisation
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Controlled crystallization of metastable polymorphic pharmaceutical: Comparative study of batchwise and continuous tubular crystallizers
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Shortcut model to evaluate the performance of continuous preferential crystallization for conglomerates forming chiral systems
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High-throughput screening of thermodynamically stable molecular crystal forms using crystal structure prediction method based on deep graph neural network
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Sculpting DNA-based synthetic cells through phase separation and phase-targeted activity
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Continuous crystallization as a downstream processing step of pharmaceutical proteins: A review
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Comprehensive evaluation of a data driven control strategy: Experimental application to a pharmaceutical crystallization process
inferred← citeshttps://doi.org/10.1016/j.cherd.2020.09.021openalex-snapshot
Crystallization process modifications to address polymorphic and particle size challenges in early stage development of an API salt
inferred← citeshttps://doi.org/10.1016/j.cherd.2020.10.029openalex-snapshot
Crystal-size distribution-based dynamic process modelling, optimization, and scaling for seeded batch cooling crystallization of Active Pharmaceutical Ingredients (API)
inferred← citeshttps://doi.org/10.1016/j.cherd.2020.12.012openalex-snapshot
Review of melt crystallization in the pharmaceutical field, towards crystal engineering and continuous process development
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.04.006openalex-snapshot
Continuous slug flow crystallization: Impact of design and operating parameters on product quality
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.04.007openalex-snapshot
Mechanistic crystal size distribution (CSD)-based modelling of continuous antisolvent crystallization of benzoic acid
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.07.029openalex-snapshot
Modeling and analysis of MSMPR cascades involving nucleation, growth and agglomeration mechanisms with slurry recycling
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.08.030openalex-snapshot
Tailoring the crystal size distribution of an active pharmaceutical ingredient by continuous antisolvent crystallization in a planar oscillatory flow crystallizer
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.09.030openalex-snapshot
Investigating the effect of operation points on crystal quality in reactive crystallization using continuous flow with high shear stress
inferred← citeshttps://doi.org/10.1016/j.cherd.2021.12.017openalex-snapshot
Archimedes tube crystallizer: Design and characterization for small-scale continuous crystallization
inferred← citeshttps://doi.org/10.1016/j.cherd.2024.01.057openalex-snapshot
Insulin nucleation kinetics in an oscillatory flow-based platform: Protein crystallization as a highly reproducible separation process
inferred← citeshttps://doi.org/10.1016/j.cherd.2025.01.003openalex-snapshot
Continuous manufacturing based paradigm shift in pharmaceuticals production and current regulatory framework
inferred← citeshttps://doi.org/10.1016/j.cherd.2025.10.032openalex-snapshot
Thermodynamic model for predicting progress of equilibrium limited reactive crystallizations
inferred← citeshttps://doi.org/10.1016/j.cis.2012.03.002openalex-snapshot
Crystals and crystallization in oil-in-water emulsions: Implications for emulsion-based delivery systems
inferred← citeshttps://doi.org/10.1016/j.cjche.2019.11.008openalex-snapshot
Recent advances of pharmaceutical crystallization theories
inferred← citeshttps://doi.org/10.1016/j.cjche.2022.05.008openalex-snapshot
Application of functionalized magnetic silica nanoparticles for selective induction of three coumarin metastable polymorphs
inferred← citeshttps://doi.org/10.1016/j.coche.2015.03.002openalex-snapshot
Heterogeneous nucleants for crystallogenesis and bioseparation
inferred← citeshttps://doi.org/10.1016/j.colsurfa.2021.128094openalex-snapshot
Controlling salt crystallization in evaporating thin films of colloidal liquids
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2013.05.027openalex-snapshot
Iterative learning control for the systematic design of supersaturation controlled batch cooling crystallisation processes
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2019.106559openalex-snapshot
Strategic evaluation of different direct nucleation control approaches for controlling batch cooling crystallisation via simulation and experimental case studies
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2020.106746openalex-snapshot
Comprehensive sensitivity analysis and process risk assessment of large scale pharmaceutical crystallization processes
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2022.108024openalex-snapshot
Population balance modeling of unstirred cooling crystallization on an integrated belt filter
inferred← citeshttps://doi.org/10.1016/j.compchemeng.2024.108680openalex-snapshot
A method for the rapid creation of AI driven crystallization process controllers
inferred← citeshttps://doi.org/10.1016/j.drudis.2016.01.014openalex-snapshot
The potential of computed crystal energy landscapes to aid solid-form development
inferred← citeshttps://doi.org/10.1016/j.ece.2024.07.001openalex-snapshot
Crystallisation: Solving crystal nucleation problem in the chemical engineering classroom based on the research grade experiments deployed in virtual mode
inferred← citeshttps://doi.org/10.1016/j.ejps.2013.03.014openalex-snapshot
Dissolution enhancement of Deflazacort using hollow crystals prepared by antisolvent crystallization process
inferred← citeshttps://doi.org/10.1016/j.ejps.2021.105958openalex-snapshot
Systematic thermodynamic analysis of apremilast polymorphs via solubility measurement with modeling: Mechanism evaluation through molecular simulation
inferred← citeshttps://doi.org/10.1016/j.eng.2017.03.023openalex-snapshot
Progress of Pharmaceutical Continuous Crystallization
inferred← citeshttps://doi.org/10.1016/j.eng.2025.02.023openalex-snapshot
Computer Vision-Assisted High-Throughput Screening of Crystallization Additives for Crystal Size, Shape, and Agglomeration Regulation
inferred← citeshttps://doi.org/10.1016/j.fluid.2015.09.013openalex-snapshot
Solubility correlation and thermodynamic analysis of two forms of Metaxalone in different pure solvents
inferred← citeshttps://doi.org/10.1016/j.fluid.2025.114524openalex-snapshot
Investigating the dissolution behavior and revealing the thermodynamic mechanism of Ethyl L-phenylalaninate hydrochloride in several neat and binary solvents
inferred← citeshttps://doi.org/10.1016/j.heliyon.2024.e39851openalex-snapshot
Maximizing similarity: Using correlation coefficients to calibrate kinetic parameters in population balance models
inferred← citeshttps://doi.org/10.1016/j.ifacol.2018.09.231openalex-snapshot
Control of a two-stage mixed suspension mixed product removal crystallizer
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.07.015openalex-snapshot
Effect of a Good buffer on the fate of metastable protein-rich droplets near physiological composition
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2013.01.044openalex-snapshot
The crystal engineering of salbutamol sulphate via simulated pulmonary surfactant monolayers
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2017.08.101openalex-snapshot
The discovery and investigation of a crystalline solid solution of an active pharmaceutical ingredient
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2018.05.069openalex-snapshot
Surface-induced crystallization of pharmaceuticals and biopharmaceuticals: A review
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2019.05.017openalex-snapshot
Quantitation of trace amorphous solifenacin succinate in pharmaceutical formulations by transmission Raman spectroscopy
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2020.119297openalex-snapshot
End-to-end continuous manufacturing of conventional compressed tablets: From flow synthesis to tableting through integrated crystallization and filtration
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2021.120199openalex-snapshot
Preparation, stabilisation, isolation and tableting of valsartan nanoparticles using a semi-continuous carrier particle mediated process
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.121517openalex-snapshot
Computational study of metformin hydrochloride nucleation in hydroxylic solvents: Experimental kinetics and DFT simulation
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2022.122172openalex-snapshot
Process intensification of atorvastatin calcium crystallization for target polymorph development via continuous combined cooling and antisolvent crystallization using an oscillatory baffled crystallizer
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2023.123509openalex-snapshot
Challenges encountered in the transfer of atorvastatin tablet manufacturing - commercial batch-based production as a basis for small-scale continuous tablet manufacturing tests
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.125994openalex-snapshot
Complex investigation of the effect mechanism of polyvinylpyrrolidone in the additive-assisted crystallization of famotidine
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2025.126478openalex-snapshot
Continuous manufacturing in pharmaceuticals: an integrated approach with NIR and Raman as PAT tools
inferred← citeshttps://doi.org/10.1016/j.jcis.2015.06.014openalex-snapshot
Up-scaling the synthesis of Cu2O submicron particles with controlled morphologies for solar H2 evolution from water
inferred← citeshttps://doi.org/10.1016/j.jcis.2026.140874openalex-snapshot
Entropic crystallization of Brownian squares through pathways governed by orientational dynamics
inferred← citeshttps://doi.org/10.1016/j.jconrel.2026.114721openalex-snapshot
Insights into development of long-acting injectable suspensions
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2012.12.013openalex-snapshot
Hollow crystal anti-solvent preparation process as a promising technique to improve dissolution of poorly soluble drugs
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2016.12.017openalex-snapshot
Modification of solid-state property of sulfasalazine by using the supercritical antisolvent process
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2019.04.031openalex-snapshot
Selective polymorphic crystal growth on self-assembled monolayer using molecular modeling as an assistant method
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2022.126601openalex-snapshot
Solubility and dissolution rate of progesterone cocrystals using 4-fluorobenzoic acid and 2-hydroxy-6-naphthoic acid as coformers
inferred← citeshttps://doi.org/10.1016/j.jcrysgro.2025.128353openalex-snapshot
Enhanced separation of d-mannitol polymorphs I and II via nucleation control in swift cooling crystallization
inferred← citeshttps://doi.org/10.1016/j.jct.2016.09.036openalex-snapshot
Solubility measurement, model evaluation and thermodynamic analysis of rivaroxaban polymorphs in organic solvents
inferred← citeshttps://doi.org/10.1016/j.jct.2018.11.026openalex-snapshot
The dissolution behavior and apparent thermodynamic analysis of temozolomide in pure and mixed solvents
inferred← citeshttps://doi.org/10.1016/j.jct.2022.106777openalex-snapshot
Correlation of solubility data and solution properties of chlorzoxazone in pure solvents
inferred← citeshttps://doi.org/10.1016/j.jddst.2021.102587openalex-snapshot
Measurement of nucleation kinetics for ibuprofen crystals from ethanol and water-ethanol mixtures
inferred← citeshttps://doi.org/10.1016/j.jiec.2017.06.009openalex-snapshot
Recent progress of continuous crystallization
inferred← citeshttps://doi.org/10.1016/j.jiec.2020.06.021openalex-snapshot
Development of novel cascade type crystallizer for continuous production of crystalline particles
inferred← citeshttps://doi.org/10.1016/j.jprocont.2019.04.011openalex-snapshot
Simultaneous design and control of an industrial two-stage mixed suspension mixed product removal crystallizer
inferred← citeshttps://doi.org/10.1016/j.jprocont.2026.103630openalex-snapshot
A tutorial overview of model predictive control for continuous crystallization: Current possibilities and future perspectives
inferred← citeshttps://doi.org/10.1016/j.jtice.2015.08.009openalex-snapshot
Recrystallization of phenacetin and sulfathiazole using the sonocrystallization process
inferred← citeshttps://doi.org/10.1016/j.molliq.2019.111421openalex-snapshot
Benzothiazolium ionic liquid-induced crystallization of active alkaloid in its alcoholic solutions
inferred← citeshttps://doi.org/10.1016/j.molliq.2020.112723openalex-snapshot
Solubility measurement, model evaluation and molecular simulations of aprepitant (form I) in eight pure solvents
inferred← citeshttps://doi.org/10.1016/j.molliq.2023.123261openalex-snapshot
Solvent–solute and non-covalent interactions on bis(4-Piperidinonium ethyl ketal) oxalate compound: DFT calculations and in silico drug-target profiling
inferred← citeshttps://doi.org/10.1016/j.molliq.2024.125104openalex-snapshot
Nucleation behaviors of p-coumaric acid in four solvents from induction time and metastable zone width: experiments and simulations
inferred← citeshttps://doi.org/10.1016/j.molliq.2026.129378openalex-snapshot
Microfluidics resolves non-classical lysozyme nucleation driven by attractive protein interactions
inferred← citeshttps://doi.org/10.1016/j.molstruc.2024.140488openalex-snapshot
Single-crystal structure, Hirshfeld surface and DFT analyses of chrysomycin A, a marine microbe-derived promising agent for anticancer and antimicrobial therapy
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.144500openalex-snapshot
Characterization and formation of diverse solid forms of trelagliptin including a novel dihydrate and two co-amorphous forms
inferred← citeshttps://doi.org/10.1016/j.partic.2024.03.011openalex-snapshot
Heterogeneous crystallization of Chlorzoxazone for modulating the physicochemical properties of crystals
inferred← citeshttps://doi.org/10.1016/j.pcrysgrow.2016.07.001openalex-snapshot
Spring and parachute: How cocrystals enhance solubility
inferred← citeshttps://doi.org/10.1016/j.powtec.2022.117255openalex-snapshot
Implementation of sonicated continuous plug flow crystallization technology for processing of acetylsalicylic acid reaction mixture
inferred← citeshttps://doi.org/10.1016/j.powtec.2022.117522openalex-snapshot
Impact of crystallization conditions and filtration cake washing on the clustering of metformin hydrochloride crystals
inferred← citeshttps://doi.org/10.1016/j.powtec.2022.117527openalex-snapshot
Evolutionary neural architecture search for surrogate models to enable optimization of industrial continuous crystallization process
inferred← citeshttps://doi.org/10.1016/j.powtec.2024.119570openalex-snapshot
Kinetics of crystal transformation of imatinib mesylate during formulation process: Selection of dry granulation in pharmaceutical process
inferred← citeshttps://doi.org/10.1016/j.powtec.2025.120934openalex-snapshot
Streamlining crystallization process scale-up using statistical modeling of experiments and complementary CFD flow fields
inferred← citeshttps://doi.org/10.1016/j.rechem.2022.100748openalex-snapshot
Exploration of various solid forms of novel (1H-Benzimidazole, 2-[4-(1,1-dimethylethyl) phenyl])
inferred← citeshttps://doi.org/10.1016/j.seppur.2022.121571openalex-snapshot
Mechanistic Modeling of a Continuous Multi-Segment Multi-Addition Antisolvent Crystallization of Benzoic Acid in a Coiled Flow Inverter (Cfi) Crystallizer
inferred← citeshttps://doi.org/10.1016/j.seppur.2025.133478openalex-snapshot
From harvest to crystalline product form: A combination of crystallization with non-chromatography pre-purification steps for monoclonal antibody capture, purification, and formulation
inferred← citeshttps://doi.org/10.1016/j.seppur.2025.134331openalex-snapshot
Porous hollow fiber membrane-based continuous cross-flow anti-solvent crystallizer for production of API nanocrystals
inferred← citeshttps://doi.org/10.1016/j.supflu.2015.10.026openalex-snapshot
Modification of indomethacin crystals using supercritical and aqueous antisolvent crystallizations
inferred← citeshttps://doi.org/10.1016/j.tca.2017.02.014openalex-snapshot
A combined approach using differential scanning calorimetry with polarized light thermomicroscopy in the investigation of ketoprofen and nicotinamide cocrystal
inferred← citeshttps://doi.org/10.1016/j.ultsonch.2015.11.025openalex-snapshot
Ultrasound-assisted modulation of concomitant polymorphism of curcumin during liquid antisolvent precipitation
inferred← citeshttps://doi.org/10.1016/j.ultsonch.2019.104743openalex-snapshot
Enhancing pharmaceutical crystallization in a flow crystallizer with ultrasound: Anti-solvent crystallization
inferred← citeshttps://doi.org/10.1016/j.ultsonch.2021.105698openalex-snapshot
Enhancing continuous reactive crystallization of lithium carbonate in multistage mixed suspension mixed product removal crystallizers with pulsed ultrasound
inferred← citeshttps://doi.org/10.1016/j.ultsonch.2021.105763openalex-snapshot
Use of enantiomeric properties of sodium chlorate to assess primary and secondary nucleation under sonication
inferred← citeshttps://doi.org/10.1016/j.xphs.2016.10.017openalex-snapshot
Using X-Ray Crystallography to Simplify and Accelerate Biologics Drug Development
inferred← citeshttps://doi.org/10.1016/j.xphs.2017.06.012openalex-snapshot
Gaining Thermodynamic Insight From Distinct Glass Formation Kinetics of Structurally Similar Organic Compounds
inferred← citeshttps://doi.org/10.1016/j.xphs.2019.07.010openalex-snapshot
Identifying, Characterizing, and Understanding Nefiracetam in Its Solid State Forms: A Potential Antidementia Drug
inferred← citeshttps://doi.org/10.1021/acs.analchem.0c00247openalex-snapshot
Potentiometric Titration Method for the Determination of Solubility Limits and p K a Values of Weak Organic Acids in Water
inferred← citeshttps://doi.org/10.1021/acs.analchem.3c00175openalex-snapshot
A Single-Entity Method for Actively Controlled Nucleation and High-Quality Protein Crystal Synthesis
inferred← citeshttps://doi.org/10.1021/acs.analchem.6b00057openalex-snapshot
Rapid Discrimination of Polymorphic Crystal Forms by Nonlinear Optical Stokes Ellipsometric Microscopy
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c00252openalex-snapshot
Direct Processing of a Flow Reaction Mixture Using Continuous Mixed Suspension Mixed Product Removal Crystallizer
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c00295openalex-snapshot
Application of Model-Free and Model-Based Quality-by-Control (QbC) for the Efficient Design of Pharmaceutical Crystallization Processes
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c00716openalex-snapshot
Polymorphic Control and Scale-Up Strategy for Antisolvent Crystallization Using a Sequential Supersaturation and Direct Nucleation Control Approach
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c00885openalex-snapshot
Continuous Protein Crystallization in Mixed-Suspension Mixed-Product-Removal Crystallizers
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c00986openalex-snapshot
Identifying the Polymorphic Outcome of Hypothetical Polymorphs in Batch and Continuous Crystallizers by Numerical Simulation
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01163openalex-snapshot
Mechanochemical Synthesis of an Ionic Cocrystal with Large Birefringence Resulting from Neutral Planar π-Conjugated Groups
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01195openalex-snapshot
Manipulating Cocrystal Size and Morphology using a Combination of Temperature Cycling and Additives
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01240openalex-snapshot
Drug Mimetic Organogelators for the Control of Concomitant Crystallization of Barbital and Thalidomide
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01312openalex-snapshot
Integrated Continuous Crystallization and Spray Drying of Insulin for Pulmonary Drug Delivery
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01605openalex-snapshot
Speciation of Substituted Benzoic Acids in Solution: Evaluation of Spectroscopic and Computational Methods for the Identification of Associates and Their Role in Crystallization
inferred← citeshttps://doi.org/10.1021/acs.cgd.0c01606openalex-snapshot
A Review of Experimental Methods for Nucleation Rate Determination in Large-Volume Batch and Microfluidic Crystallization
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