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Enthalpic Efficiency of Ligand Binding
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Outgoing claims: the papers this work cites, builds on, or argues with.
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The Design of Leadlike Combinatorial Libraries
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Binding thermodynamics of substituted diaminopyrimidine renin inhibitors
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Rational design of 6-(2,4-diaminopyrimidinyl)-1,4-benzoxazin-3-ones as small molecule renin inhibitors
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The role of molecular size in ligand efficiency
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Complex molecules: do they add value?
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Medicinal Chemistry by the Numbers: The Physicochemistry, Thermodynamics and Kinetics of Modern Drug Design
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Ligand efficiency: a useful metric for lead selection
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Ligand efficiency indices as guideposts for drug discovery
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Molecular Complexity and Its Impact on the Probability of Finding Leads for Drug Discovery
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Is There a Difference between Leads and Drugs? A Historical Perspective
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Simple Size-Independent Measure of Ligand Efficiency
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The Influence of Target Family and Functional Activity on the Physicochemical Properties of Pre-Clinical Compounds
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Generation of a Set of Simple, Interpretable ADMET Rules of Thumb
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Ligand Binding Efficiency: Trends, Physical Basis, and Implications
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Differences between High- and Low-Affinity Complexes of Enzymes and Nonenzymes
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The consequences of translational and rotational entropy lost by small molecules on binding to proteins
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The influence of lead discovery strategies on the properties of drug candidates
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Adding calorimetric data to decision making in lead discovery: a hot tip
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Unraveling principles of lead discovery: from unfrustrated energy landscapes to novel molecular anchors.
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The maximal affinity of ligands
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BindingDB: a web-accessible database of experimentally determined protein-ligand binding affinities
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PDBcal: A Comprehensive Dataset for Receptor–Ligand Interactions with Three‐dimensional Structures and Binding Thermodynamics from Isothermal Titration Calorimetry
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Incoming claims: where this work appears in other papers’ reference lists and arguments.
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