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FAst MEtabolizer (FAME): A Rapid and Accurate Predictor of Sites of Metabolism in Multiple Species by Endogenous Enzymes

https://doi.org/10.1021/ci400503s
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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Random Forest: A Classification and Regression Tool for Compound Classification and QSAR Modeling
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RS-Predictor Models Augmented with SMARTCyp Reactivities: Robust Metabolic Regioselectivity Predictions for Nine CYP Isozymes
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How Do Metabolites Differ from Their Parent Molecules and How Are They Excreted?
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Pragmatic Approaches to Using Computational Methods To Predict Xenobiotic Metabolism
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Reaction Site Mapping of Xenobiotic Biotransformations
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EaMEAD: Activation Energy Prediction of Cytochrome P450 Mediated Metabolism with Effective Atomic Descriptors
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IDSite: An Accurate Approach to Predict P450-Mediated Drug Metabolism
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Empirical Regioselectivity Models for Human Cytochromes P450 3A4, 2D6, and 2C9
inferredcites →https://doi.org/10.1021/ml100016xopenalex-snapshot
SMARTCyp: A 2D Method for Prediction of Cytochrome P450-Mediated Drug Metabolism
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ADME Optimization and Toxicity Assessment in Early- and Late-Phase Drug Discovery

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Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Additional file 10 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
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Additional file 11 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
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Additional file 12 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
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Additional file 13 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655510openalex-snapshot
Additional file 14 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655513openalex-snapshot
Additional file 1 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655516openalex-snapshot
Additional file 2 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655519openalex-snapshot
Additional file 3 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655522openalex-snapshot
Additional file 4 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655525openalex-snapshot
Additional file 5 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655528openalex-snapshot
Additional file 6 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655531openalex-snapshot
Additional file 7 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655534openalex-snapshot
Additional file 8 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.6084/m9.figshare.16655537openalex-snapshot
Additional file 9 of Constructing xenobiotic maps of metabolism to predict enzymes catalyzing metabolites capable of binding to DNA
inferred← citeshttps://doi.org/10.70675/b266e3e2za02fz4e7fz8870z4d4481176044openalex-snapshot
Approche prédictive pour évaluer la génotoxicité des contaminants de l’environnement
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Learning to predict the sites of metabolism and metabolic endpoints
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