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AlzPlatform: An Alzheimer’s Disease Domain-Specific Chemogenomics Knowledgebase for Polypharmacology and Target Identification Research

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Outgoing claims: the papers this work cites, builds on, or argues with.

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CHOLINESTERASES, A TARGET OF PHARMACOLOGY AND TOXICOLOGY

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inferred← citeshttps://doi.org/10.1016/j.ejmech.2023.115880openalex-snapshot
Multi-targeted anti-Alzheimer's agents: Synthesis, biological evaluation, and molecular modeling study of some pyrazolopyridine hybrids
inferred← citeshttps://doi.org/10.1016/j.ejmech.2024.116624openalex-snapshot
Multimechanism biological profiling of tetrahydro-β-carboline analogues as selective HDAC6 inhibitors for the treatment of Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/j.ejphar.2021.174276openalex-snapshot
Gamma-decanolactone: Preliminary evaluation as potential antiparkinsonian drug
inferred← citeshttps://doi.org/10.1016/j.ejphar.2024.176370openalex-snapshot
Investigating the therapeutic effects of novel compounds targeting inflammatory IL-1β and IL-6 signaling pathways in spinocerebellar ataxia type 3
inferred← citeshttps://doi.org/10.1016/j.ijbiomac.2021.12.056openalex-snapshot
Discovery of tight-binding competitive inhibitors of dipeptidyl peptidase IV
inferred← citeshttps://doi.org/10.1016/j.jfda.2019.08.001openalex-snapshot
Estimation of nizatidine gastric nitrosatability and product toxicity via an integrated approach combining HILIC, in silico toxicology, and molecular docking
inferred← citeshttps://doi.org/10.1016/j.lfs.2020.117912openalex-snapshot
Identification of novel class I and class IIb histone deacetylase inhibitor for Alzheimer's disease therapeutics
inferred← citeshttps://doi.org/10.1016/j.medidd.2025.100237openalex-snapshot
Repurposing oncology drugs for Alzheimer’s: multi-omic convergence targeting cell-cycle, proteostasis, immunometabolism, and senescence
inferred← citeshttps://doi.org/10.1016/j.molstruc.2023.136222openalex-snapshot
Dictamnine derivatives as a novel family of dual inhibitors for cholinesterase and β-amyloid aggregation
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.141479openalex-snapshot
The complex interplay between ligand strain, coulombic interactions, and binding site dynamics of two congeneric AChE inhibitors
inferred← citeshttps://doi.org/10.1016/j.molstruc.2025.144924openalex-snapshot
Synthesis and evaluation of novel indolopyridine derivatives as multi-target directed ligands for Alzheimer’s disease
inferred← citeshttps://doi.org/10.1016/j.neulet.2018.09.018openalex-snapshot
Pharmacogenomics of Alzheimer’s and Parkinson’s diseases
inferred← citeshttps://doi.org/10.1016/j.neulet.2024.137750openalex-snapshot
Azoles display promising anticonvulsant effects through possible PPAR-α activation
inferred← citeshttps://doi.org/10.1016/j.phymed.2020.153244openalex-snapshot
Identification of a novel BACE1 inhibitor, timosaponin A-III, for treatment of Alzheimer's disease by a cell extraction and chemogenomics target knowledgebase-guided method
inferred← citeshttps://doi.org/10.1016/j.phytochem.2017.12.016openalex-snapshot
Phytochemistry and pharmacology of the genus Leonurus: The herb to benefit the mothers and more
inferred← citeshttps://doi.org/10.1016/j.tiv.2020.104772openalex-snapshot
Lapachol acetylglycosylation enhances its cytotoxic and pro-apoptotic activities in HL60 cells
inferred← citeshttps://doi.org/10.1016/j.trci.2018.09.001openalex-snapshot
Synergism of antihypertensives and cholinesterase inhibitors in Alzheimer's disease
inferred← citeshttps://doi.org/10.1016/s1875-5364(18)30029-3openalex-snapshot
Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease
inferred← citeshttps://doi.org/10.1021/acs.jcim.0c00633openalex-snapshot
Pain-CKB, A Pain-Domain-Specific Chemogenomics Knowledgebase for Target Identification and Systems Pharmacology Research
inferred← citeshttps://doi.org/10.1021/acs.jcim.5b00748openalex-snapshot
StemCellCKB: An Integrated Stem Cell-Specific Chemogenomics KnowledgeBase for Target Identification and Systems-Pharmacology Research
inferred← citeshttps://doi.org/10.1021/acs.jcim.6c02102openalex-snapshot
An AI-Driven Chemogenomics Knowledgebase for Human-Transmissible Pathogens: A Platform for Antimicrobial Drug Discovery
inferred← citeshttps://doi.org/10.1021/acs.jcim.7b00277openalex-snapshot
ProSelection: A Novel Algorithm to Select Proper Protein Structure Subsets for in Silico Target Identification and Drug Discovery Research
inferred← citeshttps://doi.org/10.1021/acs.jcim.8b00623openalex-snapshot
DAKB-GPCRs: An Integrated Computational Platform for Drug Abuse Related GPCRs
inferred← citeshttps://doi.org/10.1021/acs.jmedchem.5c01791openalex-snapshot
QSAR Prediction of BBB Permeability Based on Machine Learning upon PETBD: A Novel Data Set of PET Tracers
inferred← citeshttps://doi.org/10.1021/acschemneuro.0c00348openalex-snapshot
Design, Synthesis, and Functional Evaluation of a Novel Series of Phosphonate-Functionalized 1,2,3-Triazoles as Positive Allosteric Modulators of α7 Nicotinic Acetylcholine Receptors
inferred← citeshttps://doi.org/10.1021/acschemneuro.0c00372openalex-snapshot
Pain Chemogenomics Knowledgebase (Pain-CKB) for Systems Pharmacology Target Mapping and Physiologically Based Pharmacokinetic Modeling Investigation of Opioid Drug–Drug Interactions
inferred← citeshttps://doi.org/10.1021/acschemneuro.0c00508openalex-snapshot
New Strategy for Reducing Tau Aggregation Cytologically by A Hairpinlike Molecular Inhibitor, Tannic Acid Encapsulated in Liposome
inferred← citeshttps://doi.org/10.1021/acschemneuro.2c00738openalex-snapshot
Mechanistic Insight into the Inhibition of Choline Acetyltransferase by Proton Pump Inhibitors
inferred← citeshttps://doi.org/10.1021/acschemneuro.3c00294openalex-snapshot
Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer’s Model in Adult Male Wistar Rats
inferred← citeshttps://doi.org/10.1021/acschemneuro.9b00109openalex-snapshot
Computational Systems Pharmacology-Target Mapping for Fentanyl-Laced Cocaine Overdose
inferred← citeshttps://doi.org/10.1021/acsomega.0c00057openalex-snapshot
Effects of α-Mangostin Derivatives on the Alzheimer’s Disease Model of Rats and Their Mechanism: A Combination of Experimental Study and Computational Systems Pharmacology Analysis
inferred← citeshttps://doi.org/10.1021/acsomega.2c04258openalex-snapshot
Virus-CKB 2.0: Viral-Associated Disease-Specific Chemogenomics Knowledgebase
inferred← citeshttps://doi.org/10.1021/acsomega.2c07934openalex-snapshot
Novel Thiosemicarbazone Quantum Dots in the Treatment of Alzheimer’s Disease Combining In Silico Models Using Fingerprints and Physicochemical Descriptors
inferred← citeshttps://doi.org/10.1021/acsomega.3c00441openalex-snapshot
Design and Computational Analysis of an MMP9 Inhibitor in Hypoxia-Induced Glioblastoma Multiforme
inferred← citeshttps://doi.org/10.1021/acsomega.9b03960openalex-snapshot
Insight into Ginkgo biloba L. Extract on the Improved Spatial Learning and Memory by Chemogenomics Knowledgebase, Molecular Docking, Molecular Dynamics Simulation, and Bioassay Validations
inferred← citeshttps://doi.org/10.1021/ci500574nopenalex-snapshot
Discovery of Multitarget-Directed Ligands against Alzheimer’s Disease through Systematic Prediction of Chemical–Protein Interactions
inferred← citeshttps://doi.org/10.1038/aps.2017.85openalex-snapshot
The efficacy and safety of cilostazol as an alternative to aspirin in Chinese patients with aspirin intolerance after coronary stent implantation: a combined clinical study and computational system pharmacology analysis
inferred← citeshttps://doi.org/10.1038/s12276-024-01295-yopenalex-snapshot
Blockade of STING activation alleviates microglial dysfunction and a broad spectrum of Alzheimer’s disease pathologies
inferred← citeshttps://doi.org/10.1038/s41380-023-01981-9openalex-snapshot
Nuclear receptor 5A2 regulation of Agrp underlies olanzapine-induced hyperphagia
inferred← citeshttps://doi.org/10.1038/s41401-018-0071-1openalex-snapshot
Computational systems pharmacology analysis of cannabidiol: a combination of chemogenomics-knowledgebase network analysis and integrated in silico modeling and simulation
inferred← citeshttps://doi.org/10.1038/s41401-019-0217-9openalex-snapshot
Structural insight into the serotonin (5-HT) receptor family by molecular docking, molecular dynamics simulation and systems pharmacology analysis
inferred← citeshttps://doi.org/10.1038/s41598-018-21468-wopenalex-snapshot
The Mechanisms of Bushen-Yizhi Formula as a Therapeutic Agent against Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1038/s41598-019-40271-9openalex-snapshot
Hybrid approach to sieve out natural compounds against dual targets in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1038/s41598-019-57004-7openalex-snapshot
Protein-bound uremic toxins are associated with cognitive function among patients undergoing maintenance hemodialysis
inferred← citeshttps://doi.org/10.1038/s41598-021-85888-xopenalex-snapshot
LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells
inferred← citeshttps://doi.org/10.1038/s41598-022-16274-4openalex-snapshot
Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells
inferred← citeshttps://doi.org/10.1038/s41598-022-25534-2openalex-snapshot
Aporphine and isoquinoline derivatives block glioblastoma cell stemness and enhance temozolomide cytotoxicity
inferred← citeshttps://doi.org/10.1038/s41598-025-91546-3openalex-snapshot
A high throughput, high content screen for non-toxic small molecules that reduce levels of the nuclear lamina protein, Lamin B1
inferred← citeshttps://doi.org/10.1038/srep33963openalex-snapshot
Cardiovascular Disease Chemogenomics Knowledgebase-guided Target Identification and Drug Synergy Mechanism Study of an Herbal Formula
inferred← citeshttps://doi.org/10.1039/c6mb00500dopenalex-snapshot
A novel strategy of profiling the mechanism of herbal medicines by combining network pharmacology with plasma concentration determination and affinity constant measurement
inferred← citeshttps://doi.org/10.1039/c7ra11831gopenalex-snapshot
Open chemoinformatic resources to explore the structure, properties and chemical space of molecules
inferred← citeshttps://doi.org/10.1039/d1ra04419bopenalex-snapshot
Indolylbenzothiadiazoles as highly tunable fluorophores for imaging lipid droplet accumulation in astrocytes and glioblastoma cells
inferred← citeshttps://doi.org/10.1039/d3ob01760eopenalex-snapshot
Metal-free synthesis of functionalized tacrine derivatives and their evaluation for acetyl/butyrylcholinesterase and α-glucosidase inhibition
inferred← citeshttps://doi.org/10.1039/d4md00778fopenalex-snapshot
Donepezil-based rational design of N -substituted quinazolinthioacetamide candidates as potential acetylcholine esterase inhibitors for the treatment of Alzheimer's disease: in vitro and in vivo studies
inferred← citeshttps://doi.org/10.1042/ebc20260007openalex-snapshot
Chemogenomic sets: valuable tools for early-stage drug discovery
inferred← citeshttps://doi.org/10.1042/etls20210249openalex-snapshot
Applied machine learning in Alzheimer's disease research: omics, imaging, and clinical data
inferred← citeshttps://doi.org/10.1073/pnas.1921531117openalex-snapshot
Lumefantrine, an antimalarial drug, reverses radiation and temozolomide resistance in glioblastoma
inferred← citeshttps://doi.org/10.1074/jbc.ra118.006307openalex-snapshot
AQAMAN, a bisamidine-based inhibitor of toxic protein inclusions in neurons, ameliorates cytotoxicity in polyglutamine disease models
inferred← citeshttps://doi.org/10.1080/07391102.2018.1426043openalex-snapshot
Docking, molecular dynamics, binding energy-MM-PBSA studies of naphthofuran derivatives to identify potential dual inhibitors against BACE-1 and GSK-3β
inferred← citeshttps://doi.org/10.1080/07391102.2020.1828170openalex-snapshot
An in silico approach to identify potential medicinal plants for treating Alzheimer disease: a case study with acetylcholinesterase
inferred← citeshttps://doi.org/10.1080/07391102.2023.2217925openalex-snapshot
Constituents of Stachys plants as potential dual inhibitors of AChE and NMDAR for the treatment of Alzheimer’s disease: a molecular docking and dynamic simulation study
inferred← citeshttps://doi.org/10.1080/07391102.2023.2289045openalex-snapshot
Probable targets and mechanism of ginsenoside Rg1 for non-alcoholic fatty liver disease: a study integrating network pharmacology, molecular docking, and molecular dynamics simulation
inferred← citeshttps://doi.org/10.1080/07391102.2024.2313166openalex-snapshot
Discovery of small molecules from natural compound databases as potent retinoid X alpha receptor agonists to treat Alzheimer’s disease
inferred← citeshttps://doi.org/10.1080/07391102.2024.2411524openalex-snapshot
Identification of novel brain penetrant GSK-3β inhibitors toward Alzheimer’s disease therapy by virtual screening, molecular docking, dynamic simulation, and MMPBSA analysis
inferred← citeshttps://doi.org/10.1080/07391102.2025.2501672openalex-snapshot
Integrating transcriptomics with disease–gene network and identification of EGFR kinase target: inhibitor discovery through virtual screening of natural compounds for brain cancer therapy
inferred← citeshttps://doi.org/10.1080/13880209.2025.2485905openalex-snapshot
Integrated pharmacoanalysis, bioinformatics analysis, and experimental validation to identify the ingredients and mechanisms of Xiao-Luo-Wan in uterine fibroids treatment
inferred← citeshttps://doi.org/10.1080/14756366.2020.1797711openalex-snapshot
Design, synthesis, and evaluation of 1, 4-benzodioxan-substituted chalcones as selective and reversible inhibitors of human monoamine oxidase B
inferred← citeshttps://doi.org/10.1080/14756366.2020.1801673openalex-snapshot
Design, synthesis and biological evaluation of edaravone derivatives bearing the N -benzyl pyridinium moiety as multifunctional anti-Alzheimer’s agents
inferred← citeshttps://doi.org/10.1080/14756366.2022.2055009openalex-snapshot
Biological investigation of N -methyl thiosemicarbazones as antimicrobial agents and bacterial carbonic anhydrases inhibitors
inferred← citeshttps://doi.org/10.1080/14786419.2023.2252152openalex-snapshot
Comparative analysis of α-pinene alone and combined with temozolomide in human glioblastoma cells
inferred← citeshttps://doi.org/10.1080/17460441.2018.1457645openalex-snapshot
Have there been improvements in Alzheimer’s disease drug discovery over the past 5 years?
inferred← citeshttps://doi.org/10.1089/neu.2018.5757openalex-snapshot
Chemogenomics Systems Pharmacology Mapping of Potential Drug Targets for Treatment of Traumatic Brain Injury
inferred← citeshttps://doi.org/10.1093/bib/bbaa155openalex-snapshot
Virus-CKB: an integrated bioinformatics platform and analysis resource for COVID-19 research
inferred← citeshttps://doi.org/10.1093/bib/bbaa260openalex-snapshot
MCCS: a novel recognition pattern-based method for fast track discovery of anti-SARS-CoV-2 drugs
inferred← citeshttps://doi.org/10.1093/bib/bbx125openalex-snapshot
Web-based drug repurposing tools: a survey
inferred← citeshttps://doi.org/10.1093/bioinformatics/btad577openalex-snapshot
A machine learning-based quantitative model (LogBB_Pred) to predict the blood–brain barrier permeability (logBB value) of drug compounds
inferred← citeshttps://doi.org/10.1093/database/bay117openalex-snapshot
GCDB: a glaucomatous chemogenomics database forin silicodrug discovery
inferred← citeshttps://doi.org/10.1101/2024.04.29.589520openalex-snapshot
Identification and validation of drugs for repurposing in Glioblastoma: a computational and experimental workflow
inferred← citeshttps://doi.org/10.1109/icacite60783.2024.10617309openalex-snapshot
Comparative Docking Strategies for Alzheimer’s Therapy: Exploring Drug and Phytocompound Interactions with BIN1 Protein
inferred← citeshttps://doi.org/10.1109/icaisc58445.2023.10200676openalex-snapshot
Histone Deacetylase 6 as A Putative Target in Alzheimer’s Disease Therapeutics
inferred← citeshttps://doi.org/10.1111/cbdd.14279openalex-snapshot
Design, synthesis and the evaluation of cholinesterase inhibition and blood‐brain permeability of daidzein derivatives or analogs
inferred← citeshttps://doi.org/10.1111/cbdd.70048openalex-snapshot
Knowledgebase‐Driven Exploration and Experimental Verification of Simvastatin's Inhibitory Impact on P2X7 / NLRP3 Inflammasome Pathway
inferred← citeshttps://doi.org/10.1111/jcmm.17410openalex-snapshot
Mechanisms of Gynostemma pentaphyllum against non‐alcoholic fibre liver disease based on network pharmacology and molecular docking
inferred← citeshttps://doi.org/10.1111/jnc.16300openalex-snapshot
Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells
inferred← citeshttps://doi.org/10.1142/s0192415x25500429openalex-snapshot
Unraveling the Mechanisms of Active Saponins from Rhizoma Anemarrhenae Against Ferroptosis in Alzheimer’s Disease: Integrating Network Pharmacology, Cell Membrane Chromatography, and Experimental Validation
inferred← citeshttps://doi.org/10.1155/2021/3058861openalex-snapshot
Novel Synthetic Coumarin‐Chalcone Derivative (E)‐3‐(3‐(4‐(Dimethylamino)Phenyl)Acryloyl)‐4‐Hydroxy‐2H‐Chromen‐2‐One Activates CREB‐Mediated Neuroprotection in Aβ and Tau Cell Models of Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1155/2021/7169211openalex-snapshot
Identifying Active Compounds and Mechanism of Camellia nitidissima Chi on Anti-Colon Cancer by Network Pharmacology and Experimental Validation
inferred← citeshttps://doi.org/10.1155/2022/1215097openalex-snapshot
Luteolin‐Rich Extract of Thespesia garckeana F. Hoffm. (Snot Apple) Contains Potential Drug‐Like Candidates and Modulates Glycemic and Oxidoinflammatory Aberrations in Experimental Animals
inferred← citeshttps://doi.org/10.1155/2022/3060579openalex-snapshot
Evaluation of Blood‐Brain‐Barrier Permeability, Neurotoxicity, and Potential Cognitive Impairment by Pseudomonas aeruginosa’s Virulence Factor Pyocyanin
inferred← citeshttps://doi.org/10.1155/2023/9935942openalex-snapshot
[Retracted] The Effective Components, Core Targets, and Key Pathways of Ginseng against Alzheimer’s Disease
inferred← citeshttps://doi.org/10.1177/1087057116635818openalex-snapshot
A Perspective on Implementing a Quantitative Systems Pharmacology Platform for Drug Discovery and the Advancement of Personalized Medicine
inferred← citeshttps://doi.org/10.1186/s12906-020-02939-yopenalex-snapshot
A bioinformatics investigation into the pharmacological mechanisms of javanica oil emulsion injection in non-small cell lung cancer based on network pharmacology methodologies
inferred← citeshttps://doi.org/10.1186/s12906-020-03022-2openalex-snapshot
Mechanisms of Spica Prunellae against thyroid-associated Ophthalmopathy based on network pharmacology and molecular docking
inferred← citeshttps://doi.org/10.1186/s13020-020-00399-7openalex-snapshot
The study of neuroprotective effects and underlying mechanism of Naoshuantong capsule on ischemia stroke mice
inferred← citeshttps://doi.org/10.1186/s13065-022-00799-wopenalex-snapshot
Synthesis, in vitro biological evaluation and molecular modelling of new 2-chloro-3-hydrazinopyrazine derivatives as potent acetylcholinesterase inhibitors on PC12 cells
inferred← citeshttps://doi.org/10.1201/9781315368863-12openalex-snapshot
High-Order Perturbation Theory Models of Drug-Target Interactomes for Proteins Expressed on Networks of Hippocampus Brain Region of Alzheimer Disease Patients
inferred← citeshttps://doi.org/10.1208/s12248-025-01059-0openalex-snapshot
GCN-BBB: Deep Learning Blood-Brain Barrier (BBB) Permeability PharmacoAnalytics with Graph Convolutional Neural (GCN) Network
inferred← citeshttps://doi.org/10.12122/j.issn.1673-4254.2021.01.02openalex-snapshot
[Network pharmacology-based study of the therapeutic mechanism of resveratrol for Alzheimer's disease].
inferred← citeshttps://doi.org/10.1371/journal.pone.0150602openalex-snapshot
In Vitro and In Vivo Characterization of the Alkaloid Nuciferine
inferred← citeshttps://doi.org/10.1371/journal.pone.0317364openalex-snapshot
Cellular senescence-associated genes in rheumatoid arthritis: Identification and functional analysis
inferred← citeshttps://doi.org/10.1517/17460441.2016.1141892openalex-snapshot
Can cloud-based tools accelerate Alzheimer’s disease drug discovery?
inferred← citeshttps://doi.org/10.15252/emmm.202012354openalex-snapshot
Targeted stabilization of Munc18‐1 function via pharmacological chaperones
inferred← citeshttps://doi.org/10.17179/excli2016-692openalex-snapshot
Novel 4-thiazolidinone derivatives as agonists of benzodiazepine receptors: design, synthesis and pharmacological evaluation
inferred← citeshttps://doi.org/10.18097/bmcrm00091openalex-snapshot
Investigation of NMDA Receptor Channel Blockers in a Series of Methylene Blue Conjugates Using QSAR and Molecular Modeling
inferred← citeshttps://doi.org/10.18632/aging.103700openalex-snapshot
Pathomechanism characterization and potential therapeutics identification for SCA3 targeting neuroinflammation
inferred← citeshttps://doi.org/10.18632/aging.204306openalex-snapshot
Novel TRKB agonists activate TRKB and downstream ERK and AKT signaling to protect Aβ-GFP SH-SY5Y cells against Aβ toxicity
inferred← citeshttps://doi.org/10.18632/aging.204954openalex-snapshot
Coumarin-chalcone hybrid LM-021 and indole derivative NC009-1 targeting inflammation and oxidative stress to protect BE(2)-M17 cells against α-synuclein toxicity
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1509729/v1openalex-snapshot
Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1509729/v2openalex-snapshot
Curcumin piperidone derivatives induce anti-proliferative and anti-migratory effects in LN-18 human glioblastoma cells
inferred← citeshttps://doi.org/10.21203/rs.3.rs-1827631/v1openalex-snapshot
An archaeal compound as a driver of Parkinson’s disease pathogenesis
inferred← citeshttps://doi.org/10.21203/rs.3.rs-3212307/v1openalex-snapshot
Investigating the Therapeutic Effects of Novel Compounds Targeting Inflammasome and IL-1β and IL-6 Signaling Pathways in Spinocerebellar Ataxia Type 3
inferred← citeshttps://doi.org/10.2174/011570159x327908241121062335openalex-snapshot
Translational Informatics Driven Drug Repositioning for Neurodegenerative Disease
inferred← citeshttps://doi.org/10.2174/1568009619666190206122149openalex-snapshot
Autophagy and Apoptosis Specific Knowledgebases-guided Systems Pharmacology Drug Research
inferred← citeshttps://doi.org/10.2174/1570159x18666191230120053openalex-snapshot
Potential Therapeutic Approaches to Alzheimer’s Disease By Bioinformatics, Cheminformatics And Predicted Adme-Tox Tools
inferred← citeshttps://doi.org/10.2174/1573399815666190326120006openalex-snapshot
Computational Drug Designing and Prediction Of Important Parameters Using in silico Methods- A Review
inferred← citeshttps://doi.org/10.2217/fnl-2017-0038openalex-snapshot
Pleiotropy and Promiscuity in Pharmacogenomics for the Treatment of Alzheimer's Disease and Related risk factors
inferred← citeshttps://doi.org/10.26434/chemrxiv-2023-nw98lopenalex-snapshot
Isolation, identification & computational screening of phytochemical from the seed of wild pistachio
inferred← citeshttps://doi.org/10.26434/chemrxiv.12854927openalex-snapshot
Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated Neuroprotection
inferred← citeshttps://doi.org/10.26434/chemrxiv.12854927.v1openalex-snapshot
Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated Neuroprotection
inferred← citeshttps://doi.org/10.26434/chemrxiv.12854927.v2openalex-snapshot
Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated Neuroprotection
inferred← citeshttps://doi.org/10.26434/chemrxiv.12854927.v3openalex-snapshot
Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated Neuroprotection
inferred← citeshttps://doi.org/10.26434/chemrxiv.12854927.v4openalex-snapshot
Quantum Chemical Studies and Pharmacophore Modeling for Designing Novel Keap1 Antagonists that Enhance Nrf2 Mediated Neuroprotection
inferred← citeshttps://doi.org/10.31142/ijtsrd14389openalex-snapshot
The Discovery of Potential Acetyl Cholinesterase Inhibitors: A Combination of Virtual Screening and Molecular Docking Studies
inferred← citeshttps://doi.org/10.33472/afjbs.3.2.2021.130-180openalex-snapshot
Quantum chemical studies and pharmacophore modeling for designing novel keap1 antagonists that enhance nrf2 mediated neuroprotection
inferred← citeshttps://doi.org/10.3389/fimmu.2022.872470openalex-snapshot
Leveraging Bulk and Single-Cell RNA Sequencing Data of NSCLC Tumor Microenvironment and Therapeutic Potential of NLOC-15A, A Novel Multi-Target Small Molecule
inferred← citeshttps://doi.org/10.3389/fnagi.2024.1437138openalex-snapshot
Coumarin-chalcone derivatives as dual NLRP1 and NLRP3 inflammasome inhibitors targeting oxidative stress and inflammation in neurotoxin-induced HMC3 and BE(2)-M17 cell models of Parkinson's disease
inferred← citeshttps://doi.org/10.3389/fnins.2016.00177openalex-snapshot
One for All? Hitting Multiple Alzheimer's Disease Targets with One Drug
inferred← citeshttps://doi.org/10.3389/fonc.2021.625899openalex-snapshot
Study of Combinatorial Drug Synergy of Novel Acridone Derivatives With Temozolomide Using in-silico and in-vitro Methods in the Treatment of Drug-Resistant Glioma
inferred← citeshttps://doi.org/10.3389/fphar.2020.00381openalex-snapshot
Systems Pharmacology Approach to Investigate the Mechanism of Kai-Xin-San in Alzheimer’s Disease
inferred← citeshttps://doi.org/10.3389/fphar.2021.691234openalex-snapshot
Pro-Oncogenic c-Met/EGFR, Biomarker Signatures of the Tumor Microenvironment are Clinical and Therapy Response Prognosticators in Colorectal Cancer, and Therapeutic Targets of 3-Phenyl-2H-benzo[e][1,3]-Oxazine-2,4(3H)-Dione Derivatives
inferred← citeshttps://doi.org/10.3389/fphar.2025.1616144openalex-snapshot
Neurotherapeutics across blood–brain barrier: screening of BBB-permeable and CNS-active molecules for neurodegenerative disease
inferred← citeshttps://doi.org/10.3389/fphar.2026.1766852openalex-snapshot
Exploring the anti-diabetic potential of peimisine through bioinformatics analysis and in vitro studies
inferred← citeshttps://doi.org/10.3390/antiox12122044openalex-snapshot
A Multitarget Approach against Neuroinflammation: Alkyl Substituted Coumarins as Inhibitors of Enzymes Involved in Neurodegeneration
inferred← citeshttps://doi.org/10.3390/biom11111692openalex-snapshot
Advanced Bioinformatics Tools in the Pharmacokinetic Profiles of Natural and Synthetic Compounds with Anti-Diabetic Activity
inferred← citeshttps://doi.org/10.3390/biom15081105openalex-snapshot
In Silico and In Vivo Pharmacological Evaluation of Iridoid Compounds: Geniposide and Asperuloside Profile Study Through Molecular Docking Assay and in the Caenorhabditis elegans Model
inferred← citeshttps://doi.org/10.3390/biomedicines9111582openalex-snapshot
Identification of NSP3 (SH2D3C) as a Prognostic Biomarker of Tumor Progression and Immune Evasion for Lung Cancer and Evaluation of Organosulfur Compounds from Allium sativum L. as Therapeutic Candidates
inferred← citeshttps://doi.org/10.3390/brainsci15060637openalex-snapshot
Integrated Workflow for Drug Repurposing in Glioblastoma: Computational Prediction and Preclinical Validation of Therapeutic Candidates
inferred← citeshttps://doi.org/10.3390/cells10081946openalex-snapshot
Identification of Novel Cathepsin B Inhibitors with Implications in Alzheimer’s Disease: Computational Refining and Biochemical Evaluation
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