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Discovery and Biological Evaluation of a New Family of Potent Modulators of Multidrug Resistance: Reversal of Multidrug Resistance of Mouse Lymphoma Cells by New Natural Jatrophane Diterpenoids Isolated from Euphorbia Species

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1016/0031-9422(89)80360-7openalex-snapshot

Diterpenes from Euphorbia helioscopia

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Certain calcium channel blockers bind specifically to multidrug-resistant human KB carcinoma membrane vesicles and inhibit drug binding to P-glycoprotein.

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A diterpene from Euphorbia maddeni

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Jatrophane diterpenoids from Euphorbia esula

inferredcites →https://doi.org/10.1016/s0031-9422(99)00088-6openalex-snapshot

Jatrophane diterpenoids from Euphorbia peplus

inferredcites →https://doi.org/10.1016/s0040-4020(00)00278-7openalex-snapshot

Serrulatin A and B, New Diterpene Polyesters from Euphorbia serrulata

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Euphosalicin, a new diterpene polyester with multidrug resistance reversing activity from Euphorbia salicifolia

inferredcites →https://doi.org/10.1021/np960669copenalex-snapshot

Macrocyclic Diterpene Polyesters of the Jatrophane Type from Euphorbia esula

inferredcites →https://doi.org/10.1021/np970507wopenalex-snapshot

Macrocyclic Diterpenoids from Euphorbia semiperfoliata

inferredcites →https://doi.org/10.1080/09687680010030200openalex-snapshot

Multidrug transporters in prokaryotic and eukaryotic cells: physiological functions and transport mechanisms

inferredcites →https://doi.org/10.1107/s0108767383001762openalex-snapshot

On enantiomorph-polarity estimation

inferredcites →https://doi.org/10.2172/369685openalex-snapshot

ORTEP-III: Oak Ridge Thermal Ellipsoid Plot Program for crystal structure illustrations

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Role of Plant Secondary Metabolites as Modulators of Multidrug Resistance in Cancer Therapy

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Synergistic interaction between p-glycoprotein modulators and epirubicine on resistant cancer cells

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Discovery of a novel highly potent and low-toxic jatrophane derivative enhancing the P-glycoprotein-mediated doxorubicin sensitivity of MCF-7/ADR cells

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Jatrophane diterpenoid esters from Euphorbia sororia serving as multidrug resistance reversal agents

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Jatrophane diterpenes from Euphorbia Sororia enhance chemotherapy drugs sensitivities in P-gp-induced multidrug resistance cells

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Oxazolidinones as chiral auxiliaries in asymmetric aldol reaction applied to natural products total synthesis

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Regioselective hydroxylation of lathyrane diterpenoids biocatalyzed by microorganisms and its application in integrated synthesis

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NMR and SC-XRD analyses of a solid solution of diastereomers of microphyllane diterpenoids from Salvia hirsuta

inferred← citeshttps://doi.org/10.1016/j.phymed.2018.02.001openalex-snapshot

Mechanism of action of cytotoxic compounds from the seeds of Euphorbia lathyris

inferred← citeshttps://doi.org/10.1016/j.phytochem.2005.06.008openalex-snapshot

Multidrug resistance reversal agent from Jatropha elliptica

inferred← citeshttps://doi.org/10.1016/j.phytochem.2006.06.030openalex-snapshot

Chemistry and biological activity of secondary metabolites in Euphorbia from Iran

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Bioactive diterpenoids from Croton laevigatus

inferred← citeshttps://doi.org/10.1016/j.phytochem.2018.01.016openalex-snapshot

Jatrophane diterpenoids with multidrug-resistance modulating activity from the latex of Euphorbia nicaeensis

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Ingol, ent-atisane, and stachane-type diterpenoids from Euphorbia deightonii with multidrug resistance reversing activity

inferred← citeshttps://doi.org/10.1016/j.tet.2004.04.028openalex-snapshot

New tri- and tetracyclic diterpenes from Euphorbia villosa

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Amygdaloidins A–L, twelve new 13 α-OH jatrophane diterpenes from Euphorbia amygdaloides L.

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New premyrsinane-type diterpene polyesters from Euphorbia falcata

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Jatrophane diterpenoids with multidrug resistance-modulating activity from Euphorbia mongolica Prokh.

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Jatrophane diterpenes from Euphorbia guyoniana are new potent inhibitors of atrial GIRK channels

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Modular Biomimetic Strategy Enabled Discovery of Simplified Pseudo-Natural Macrocyclic P-Glycoprotein Inhibitors Capable of Overcoming Multidrug Resistance

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Jatrophane Diterpenoids as Modulators of P-Glycoprotein-Dependent Multidrug Resistance (MDR): Advances of Structure–Activity Relationships and Discovery of Promising MDR Reversal Agents

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Epoxylathyrol Derivatives: Modulation of ABCB1-Mediated Multidrug Resistance in Human Colon Adenocarcinoma and Mouse T-Lymphoma Cells

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Evaluation of Jatrophane Esters from Euphorbia spp. as Modulators of Candida albicans Multidrug Transporters

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Pepluanols C–D, Two Diterpenoids with Two Skeletons from Euphorbia peplus

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Chemical and Pharmacological Research of the Plants in Genus Euphorbia

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Euphorbia Diterpenes: Isolation, Structure, Biological Activity, and Synthesis (2008–2012)

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Jatrophane Diterpenes as P-Glycoprotein Inhibitors. First Insights of Structure−Activity Relationships and Discovery of a New, Powerful Lead

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Jatrophane Diterpenes as Modulators of Multidrug Resistance. Advances of Structure−Activity Relationships and Discovery of the Potent Lead Pepluanin A

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Total Synthesis of Natural and Non-Natural Δ5,6Δ12,13-Jatrophane Diterpenes and Their Evaluation as MDR Modulators

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Total Synthesis of Lathyranoic Acid A

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Natural Product Extracts of Plant and Marine Origin Having Antileukemia Potential. The NCI Experience

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Bacterial efflux pump inhibitors from natural sources

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Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents

inferred← citeshttps://doi.org/10.3389/fphar.2022.815603openalex-snapshot

Research Progress on Natural Diterpenoids in Reversing Multidrug Resistance

inferred← citeshttps://doi.org/10.3390/molecules31173024openalex-snapshot

Jatrophane Diterpenoids from Euphorbia peplus with LysoTracker-Associated Cellular Activity

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