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Identification of Metabolic Pathways in Daphnia magna Explaining Hormetic Effects of Selective Serotonin Reuptake Inhibitors and 4-Nonylphenol Using Transcriptomic and Phenotypic Responses

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/etc.27openalex-snapshot
Antidepressants and their metabolites in municipal wastewater, and downstream exposure in an urban watershed
inferredcites →https://doi.org/10.1002/etc.34openalex-snapshot
Adverse outcome pathways: A conceptual framework to support ecotoxicology research and risk assessment
inferredcites →https://doi.org/10.1002/etc.5620160920openalex-snapshot
Metabolic androgenization of female Daphnia magna by the xenoestrogen 4-nonylphenol
inferredcites →https://doi.org/10.1002/etc.5620190720openalex-snapshot
Offspring fitness inDaphnia: Is theDaphniareproduction test appropriate for extrapolating effects on the population level?
inferredcites →https://doi.org/10.1006/dbio.2000.9650openalex-snapshot
The Ecdysone Regulatory Pathway Controls Wing Morphogenesis and Integrin Expression during Drosophila Metamorphosis
inferredcites →https://doi.org/10.1007/s00244-007-9079-0openalex-snapshot
Effects of Environmental Contaminants on Hemoglobin Gene Expression in Daphnia magna: A Potential Biomarker for Freshwater Quality Monitoring
inferredcites →https://doi.org/10.1007/s004420100712openalex-snapshot
Phenotypic plasticity in Daphnia magna Straus: variable maturation instar as an adaptive response to predation pressure
inferredcites →https://doi.org/10.1016/j.aquatox.2005.09.009openalex-snapshot
Ecotoxicology of human pharmaceuticals
inferredcites →https://doi.org/10.1016/j.aquatox.2007.10.005openalex-snapshot
Poor elemental food quality reduces the toxicity of fluoxetine on Daphnia magna
inferredcites →https://doi.org/10.1016/j.aquatox.2009.01.013openalex-snapshot
Endocrine disrupting chemicals in fish: Developing exposure indicators and predictive models of effects based on mechanism of action
inferredcites →https://doi.org/10.1016/j.aquatox.2009.12.023openalex-snapshot
Gene transcription in Daphnia magna: Effects of acute exposure to a carbamate insecticide and an acetanilide herbicide
inferredcites →https://doi.org/10.1016/j.aquatox.2011.06.006openalex-snapshot
A genomic and ecotoxicological perspective of DNA array studies in aquatic environmental risk assessment
inferredcites →https://doi.org/10.1016/j.aquatox.2011.12.003openalex-snapshot
Enhanced offspring production in Daphnia magna clones exposed to serotonin reuptake inhibitors and 4-nonylphenol. Stage- and food-dependent effects
inferredcites →https://doi.org/10.1016/j.aquatox.2012.09.008openalex-snapshot
Adverse outcome pathways during zebrafish embryogenesis: A case study with paraoxon
inferredcites →https://doi.org/10.1016/j.bbapap.2008.06.018openalex-snapshot
Characterization of mitochondrial trifunctional protein and its inactivation study for medicine development
inferredcites →https://doi.org/10.1016/j.biocel.2011.10.010openalex-snapshot
Serotonin modulates hepatic 6-phosphofructo-1-kinase in an insulin synergistic manner
inferredcites →https://doi.org/10.1016/j.chemolab.2008.08.004openalex-snapshot
Biomarker discovery in mass spectral profiles by means of selectivity ratio plot
inferredcites →https://doi.org/10.1016/j.chemosphere.2006.09.076openalex-snapshot
Daphnia magna and ecotoxicogenomics: Gene expression profiles of the anti-ecdysteroidal fungicide fenarimol using energy-, molting- and life stage-related cDNA libraries
inferredcites →https://doi.org/10.1016/j.chroma.2008.01.063openalex-snapshot
Occurrence of selective serotonin reuptake inhibitors in sewage and receiving waters at Spitsbergen and in Norway
inferredcites →https://doi.org/10.1016/j.envint.2009.12.006openalex-snapshot
Mixtures of similarly acting compounds in Daphnia magna: From gene to metabolite and beyond
inferredcites →https://doi.org/10.1016/j.envpol.2008.08.007openalex-snapshot
Sorption of alkylphenols on Ebro River sediments: Comparing isotherms with field observations in river water and sediments
inferredcites →https://doi.org/10.1016/j.jchemneu.2012.01.001openalex-snapshot
Effect of fluoxetine on the expression of tryptophan hydroxylase and 14-3-3 protein in the dorsal raphe nucleus and hippocampus of rat
inferredcites →https://doi.org/10.1016/j.scitotenv.2010.09.026openalex-snapshot
Impacts of emerging organic contaminants on freshwater resources: Review of recent occurrences, sources, fate and effects
inferredcites →https://doi.org/10.1016/s0166-445x(99)00038-7openalex-snapshot
Determining the ecotoxicological mode of action of chemicals from measurements made on individuals: results from instar-based tests with Daphnia magna Straus
inferredcites →https://doi.org/10.1016/s0169-7439(01)00155-1openalex-snapshot
PLS-regression: a basic tool of chemometrics
inferredcites →https://doi.org/10.1021/es011055jopenalex-snapshot
Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance
inferredcites →https://doi.org/10.1021/es0615573openalex-snapshot
Daphnia magna Ecotoxicogenomics Provides Mechanistic Insights into Metal Toxicity
inferredcites →https://doi.org/10.1021/es201095ropenalex-snapshot
Physiological and Molecular Effect Assessment versus Physico-Chemistry Based Mode of Action Schemes: Daphnia magna Exposed to Narcotics and Polar Narcotics
inferredcites →https://doi.org/10.1021/es201245bopenalex-snapshot
Assessment of Chemical Mixtures and Groundwater Effects on Daphnia magna Transcriptomics
inferredcites →https://doi.org/10.1021/es203157fopenalex-snapshot
Mechanisms of Action of Selective Serotonin Reuptake Inhibitors in Daphnia magna
inferredcites →https://doi.org/10.1021/es3001618openalex-snapshot
Toxicogenomic Responses of Nanotoxicity in Daphnia magna Exposed to Silver Nitrate and Coated Silver Nanoparticles
inferredcites →https://doi.org/10.1021/es301100jopenalex-snapshot
Identification of Pathways, Gene Networks, and Paralogous Gene Families in Daphnia pulex Responding to Exposure to the Toxic Cyanobacterium Microcystis aeruginosa
inferredcites →https://doi.org/10.1021/es303505zopenalex-snapshot
Predicting Fish Acute Toxicity Using a Fish Gill Cell Line-Based Toxicity Assay
inferredcites →https://doi.org/10.1021/es800262kopenalex-snapshot
Gene Expression Profiling in Daphnia magna, Part II: Validation of a Copper Specific Gene Expression Signature with Effluent from Two Copper Mines in California
inferredcites →https://doi.org/10.1021/es803702aopenalex-snapshot
Biomarker Discovery and Transcriptomic Responses inDaphnia magnaexposed to Munitions Constituents
inferredcites →https://doi.org/10.1023/b:ectx.0000037188.09072.deopenalex-snapshot
Experimental Designs to Assess Endocrine Disrupting Effects in Invertebrates A Review
inferredcites →https://doi.org/10.1042/bj20040752openalex-snapshot
6-Phosphofructo-2-kinase/fructose-2,6-bisphosphatase: head-to-head with a bifunctional enzyme that controls glycolysis
inferredcites →https://doi.org/10.1051/limn/2004024openalex-snapshot
Testing physiologically-based resource allocation rules in laboratory experiments with Daphnia magna Straus.
inferredcites →https://doi.org/10.1074/jbc.r200008200openalex-snapshot
The Ceramide-centric Universe of Lipid-mediated Cell Regulation: Stress Encounters of the Lipid Kind
inferredcites →https://doi.org/10.1126/science.1197761openalex-snapshot
The Ecoresponsive Genome of Daphnia pulex
inferredcites →https://doi.org/10.1146/annurev.ento.51.110104.151143openalex-snapshot
DOPA DECARBOXYLASE: A Model Gene-Enzyme System for Studying Development, Behavior, and Systematics
inferredcites →https://doi.org/10.1186/gb-2008-9-2-r40openalex-snapshot
Systems biology meets stress ecology: linking molecular and organismal stress responses in Daphnia magna
inferredcites →https://doi.org/10.1289/ehp.001081133openalex-snapshot
Embryotoxicity of the Alkylphenol Degradation Product 4-Nonylphenol to the Crustacean Daphnia magna
inferredcites →https://doi.org/10.1289/ehp.99107s6907openalex-snapshot
Pharmaceuticals and Personal Care Products in the Environment: Agents of Subtle Change?
inferredcites →https://doi.org/10.2144/03342mt01openalex-snapshot
TM4: A Free, Open-Source System for Microarray Data Management and Analysis
inferredcites →https://doi.org/10.2307/3546152openalex-snapshot
A Maturation Size Threshold and Phenotypic Plasticity of Age and Size at Maturity in Daphnia magna

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Effects of Common Artificial Sweeteners at Environmentally Relevant Concentrations on Soil Springtails and Their Gut Microbiota
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inferred← citeshttps://doi.org/10.1002/etc.2662openalex-snapshot
Development of an adverse outcome pathway for acetylcholinesterase inhibition leading to acute mortality
inferred← citeshttps://doi.org/10.1002/etc.3604openalex-snapshot
Metabolomic responses to sublethal contaminant exposure in neonate and adultDaphnia magna
inferred← citeshttps://doi.org/10.1002/etc.4079openalex-snapshot
How omics technologies can enhance chemical safety regulation: perspectives from academia, government, and industry
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Daphnia magna Gut-Specific Transcriptomic Responses to Feeding Inhibiting Chemicals and Food Limitation
inferred← citeshttps://doi.org/10.1007/978-3-030-69023-6_31-1openalex-snapshot
Toxicological Effects of Nanomaterials in Terrestrial and Aquatic Insects
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inferred← citeshttps://doi.org/10.1007/s00128-016-1936-yopenalex-snapshot
Sublethal Effects of Chlorine-Free Kraft Mill Effluents on Daphnia magna
inferred← citeshttps://doi.org/10.1007/s10646-016-1667-1openalex-snapshot
Daphnia magna’s sense of competition: intra-specific interactions (ISI) alter life history strategies and increase metals toxicity
inferred← citeshttps://doi.org/10.1007/s10646-017-1803-6openalex-snapshot
Assessing the environmental hazard of individual and combined pharmaceuticals: acute and chronic toxicity of fluoxetine and propranolol in the crustacean Daphnia magna
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Behaviour of freshwater snails (Radix balthica) exposed to the pharmaceutical sertraline under simulated predation risk
inferred← citeshttps://doi.org/10.1007/s11356-014-3702-1openalex-snapshot
Sub-chronic exposure to fluoxetine in juvenile oysters (Crassostrea gigas): uptake and biological effects
inferred← citeshttps://doi.org/10.1007/s11356-019-04318-8openalex-snapshot
Metabolomic responses to pre-chlorinated and final effluent wastewater with the addition of a sub-lethal persistent contaminant in Daphnia magna
inferred← citeshttps://doi.org/10.1007/s11356-023-26169-0openalex-snapshot
Freshwater crustacean exposed to active pharmaceutical ingredients: ecotoxicological effects and mechanisms
inferred← citeshttps://doi.org/10.1007/s44169-021-00002-6openalex-snapshot
A Review on the Water Quality Criteria of Nonylphenol and the Methodological Construction for Reproduction Toxicity Endocrine Disrupting Chemicals
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Functional Data Analysis: Omics for Environmental Risk Assessment
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Behavioural and transcriptional changes in the amphipod Echinogammarus marinus exposed to two antidepressants, fluoxetine and sertraline
inferred← citeshttps://doi.org/10.1016/j.aquatox.2013.12.003openalex-snapshot
The biological effects of antidepressants on the molluscs and crustaceans: A review
inferred← citeshttps://doi.org/10.1016/j.aquatox.2015.07.019openalex-snapshot
Low environmental levels of neuro-active pharmaceuticals alter phototactic behaviour and reproduction in Daphnia magna
inferred← citeshttps://doi.org/10.1016/j.aquatox.2022.106200openalex-snapshot
Are “liquid plastics” a new environmental threat? The case of polyvinyl alcohol
inferred← citeshttps://doi.org/10.1016/j.cbd.2016.01.004openalex-snapshot
1H NMR-based metabolomics of Daphnia magna responses after sub-lethal exposure to triclosan, carbamazepine and ibuprofen
inferred← citeshttps://doi.org/10.1016/j.cbpc.2020.108875openalex-snapshot
Transgenerational reproductive effects of two serotonin reuptake inhibitors after acute exposure in Daphnia magna embryos
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2015.03.028openalex-snapshot
Chronic toxicity evaluation of the flame retardant tris (2-butoxyethyl) phosphate (TBOEP) using Daphnia magna transcriptomic response
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2018.08.027openalex-snapshot
Behavioral responses and starvation survival of Daphnia magna exposed to fluoxetine and propranolol
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2022.136671openalex-snapshot
Acute and chronic ecotoxicological effects of pharmaceuticals and their mixtures in Daphnia similis
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2023.140393openalex-snapshot
Delicate plasticity: Maladaptive responses to fish predation risk in Daphnia magna caused by sertraline pollution
inferred← citeshttps://doi.org/10.1016/j.ecoenv.2013.11.026openalex-snapshot
Exposures to a selective serotonin reuptake inhibitor (SSRI), sertraline hydrochloride, over multiple generations: Changes in life history traits in Ceriodaphnia dubia
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The antidepressant, sertraline, impacts growth and reproduction in the benthic deposit feeder, Tubifex tubifex
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Examination of the effects of toxicity and nutrition on a two-prey one-predator system with a metabolomics-inspired model
inferred← citeshttps://doi.org/10.1016/j.envint.2024.108496openalex-snapshot
Effects of common artificial sweeteners at environmentally relevant concentrations on soil springtails and their gut microbiota
inferred← citeshttps://doi.org/10.1016/j.envpol.2019.02.102openalex-snapshot
Time-dependent transcriptomic responses of Daphnia magna exposed to metabolic disruptors that enhanced storage lipid accumulation.
inferred← citeshttps://doi.org/10.1016/j.envpol.2020.114450openalex-snapshot
Chronic exposure to a pervasive pharmaceutical pollutant erodes among-individual phenotypic variation in a fish
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Combining short-term bioassays using fish and crustacean model organisms with ToxCast in vitro data and broad-spectrum chemical analysis for environmental risk assessment of the river water (Sava, Croatia)
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Comparative analysis of transcriptomic points-of-departure (tPODs) and apical responses in embryo-larval fathead minnows exposed to fluoxetine
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Post-embryonic consequences of embryonic exposure: Mechanisms of Developmental Toxicity Induced by selective serotonin re-uptake inhibitors and tributyltin in Daphnia magna
inferred← citeshttps://doi.org/10.1016/j.isci.2023.108417openalex-snapshot
Lipid metabolism analysis providing insights into nonylphenol multi-toxicity mechanism
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Unveiling the multilevel impact of four water-soluble polymers on Daphnia magna: From proteome to behaviour (a case study)
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Assessment of the effects of paroxetine and zinc on crustaceans through integrated quantitative and taxon/functional tools with a focus on free-living marine copepods and amphipods
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Transcriptomic, biochemical and individual markers in transplanted Daphnia magna to characterize impacts in the field
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Compounds altering fat storage in Daphnia magna
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Using a new high-throughput video-tracking platform to assess behavioural changes in Daphnia magna exposed to neuro-active drugs
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Graphene oxide nanosheets mitigate the developmental toxicity of TDCIPP in zebrafish via activating the mitochondrial respiratory chain and energy metabolism
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Changes in lipid profiles in Daphnia magna individuals exposed to low environmental levels of neuroactive pharmaceuticals
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Androgenic activation, impairment of the monoaminergic system and altered behavior in zebrafish larvae exposed to environmental concentrations of fenitrothion
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2024.170463openalex-snapshot
Developmental defects in cognition, metabolic and cardiac function following maternal exposures to low environmental levels of selective serotonin re-uptake inhibitors and tributyltin in Daphnia magna
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Data analysis strategies for targeted and untargeted LC-MS metabolomic studies: Overview and workflow
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Perfluoroalkylated Substance Effects in Xenopus laevis A6 Kidney Epithelial Cells Determined by ATR-FTIR Spectroscopy and Chemometric Analysis
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Microplastics Enhance the Prevalence of Antibiotic Resistance Genes in Anaerobic Sludge Digestion by Enriching Antibiotic-Resistant Bacteria in Surface Biofilm and Facilitating the Vertical and Horizontal Gene Transfer
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Gene Transcription, Metabolite and Lipid Profiling in Eco-Indicator Daphnia magna Indicate Diverse Mechanisms of Toxicity by Legacy and Emerging Flame-Retardants
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Depressing Antidepressant: Fluoxetine Affects Serotonin Neurons Causing Adverse Reproductive Responses in Daphnia magna
inferred← citeshttps://doi.org/10.1021/acs.est.7b05050openalex-snapshot
Multigenerational Effects of the Antibiotic Tetracycline on Transcriptional Responses of Daphnia magna and Its Relationship to Higher Levels of Biological Organizations
inferred← citeshttps://doi.org/10.1021/acs.est.9b03228openalex-snapshot
Effects of Single and Combined Low Concentrations of Neuroactive Drugs on Daphnia magna Reproduction and Transcriptomic Responses
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Evaluation of Cyclophosphamide on the Behavior and Reproduction of Daphnia magna
inferred← citeshttps://doi.org/10.1038/s41598-018-19778-0openalex-snapshot
Tryptophan hydroxylase (TRH) loss of function mutations induce growth and behavioral defects in Daphnia magna
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Tryptophan hydroxylase (TRH) loss of function mutations in Daphnia deregulated growth, energetic, serotoninergic and arachidonic acid metabolic signalling pathways
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Effect of the lipid regulator Gemfibrozil in the Cladocera Daphnia magna at different temperatures
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Omega‐3 PUFA profoundly affect neural, physiological, and behavioural competences – implications for systemic changes in trophic interactions
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Nanoplastics modulate the outcome of a zooplankton–microparasite interaction
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Differential gene transcription across the life cycle in Daphnia magna using a new all genome custom-made microarray
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Obesogens beyond Vertebrates: Lipid Perturbation by Tributyltin in the Crustacean Daphnia magna
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Transcriptomic, cellular and life-history responses of Daphnia magna chronically exposed to benzotriazoles: Endocrine-disrupting potential and molting effects
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Relating suborganismal processes to ecotoxicological and population level endpoints using a bioenergetic model
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Machine Learning Models for Identification and Prediction of Toxic Organic Compounds Using Daphnia magna Transcriptomic Profiles
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Targeted Metabolomic Assessment of the Sub-Lethal Toxicity of Halogenated Acetic Acids (HAAs) to Daphnia magna
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Environmental Antidepressants Disrupt Metabolic Pathways in Spirostomum ambiguum and Daphnia magna: Insights from LC-MS-Based Metabolomics
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High-Throughput Screening of Psychotropic Compounds: Impacts on Swimming Behaviours in Artemia franciscana
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From Targeted Quantification to Untargeted Metabolomics
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Évaluation de la toxicité de molécules médicamenteuses par une étude des réponses comportementales, physiologiques et transcriptomiques d’un mollusque dulçaquicole (Radix balthica) et d’un plathelminthe (Schmidtea polychroa)
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