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Kinetics of RNA Degradation by Specific Base Catalysis of Transesterification Involving the 2‘-Hydroxyl Group

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

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Interactions of metal ions with polynucleotides and related compounds. IV. Degradation of polyribonucleotides by zinc and other divalent metal ions,
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Limits to Catalysis by Ribonuclease A
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Principles of Nucleic Acid Structure
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Depolymerization of ribonucleic acid by plumbous ion
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Enzymatic reaction mechanisms
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A DNA enzyme with Mg2+-dependent RNA phosphoesterase activity
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Kinetics of intermolecular cleavage by hammerhead ribozymes
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Structural Determinants of Enzymic Processivity
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Interaction of metal ions with nucleic acids and related compounds. XVII. Mechanism of degradation of polyribonucleotides and oligoribonucleotides by zinc(II)) ions
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Improved Nearest-Neighbor Parameters for Predicting DNA Duplex Stability
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Chemical nucleases
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Inorganic Mimics of Ribonucleases and Ribozymes: From Random Cleavage to Sequence-Specific Chemistry to Catalytic Antisense Drugs
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Kinetics and Mechanisms for the Cleavage and Isomerization of the Phosphodiester Bonds of RNA by Brønsted Acids and Bases
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Hydration and dehydration of phosphoric acid derivatives: free energies of formation of the pentacoordinate intermediates for phosphate ester hydrolysis and of monomeric metaphosphate
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Poly(tertiary phosphines and arsines). 15. Some polyphosphines with terminal dialkylamino and alkoxy groups
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Thermodynamics of Proton Dissociation in Dilute Aqueous Solution. V. An Entropy Titration Study of Adenosine, Pentoses, Hexoses, and Related Compounds1a,b
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Hydrogen Atom Transfer between Free Radicals and Their Diamagnetic Precursors
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Nucleophilic reactivity constants toward methyl iodide and trans-dichlorodi(pyridine)platinum(II)
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Proton Ionization from Adenosine
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Absolute Configurations of Sulfoxides by Asymmetric Oxidation of Sulfides1
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The Kinetics of Hydrolysis of Ribonucleic Acid
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Elastoviscous Properties of Polyisobutylene. VI. Relation between Stress Relaxation Modulus and Dynamic Modulus
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Nucleotide-Amino Acid Complexes in Alkaline Digests of Ribonucleic Acid*
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The Mechanism of the Alkaline Hydrolysis of Ribonucleic Acids
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The Embedded Ribonucleotide Assay: A Chimeric Substrate for Studying Cleavage of RNA by Transesterification
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Synthesis and Characterization of an RNA Dinucleotide Containing a 3‘-S-Phosphorothiolate Linkage
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Interconversion and phosphoester hydrolysis of 2',5'- and 3',5'-dinucleoside monophosphates: kinetics and mechanisms
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Selenoxide elimination for the synthesis of unsaturated-sugar uracil nucleosides
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Ionophoresis of Oligosaccharides as N-Benzylglycosylammonium Ions
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A small catalytic oligoribonucleotide
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Heliomagnetic dipole moment and daily variation of cosmic rays underground
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Young formation age of a mantle plume source
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ON THE MECHANISM OF RIBONUCLEASE ACTION
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Hydrolytic stability of helical RNA: a selective advantage for the natural 3',5'-bond.
inferredcites →https://doi.org/10.1073/pnas.95.5.2233openalex-snapshot
Cleaving DNA with DNA
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Lange’s Handbook of Chemistry
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Metal ion-dependent hydrolysis of RNA phosphodiester bonds within hairpin loops. A comparative kinetic study on chimeric ribo/2'-O-methylribo oligonucleotides
inferredcites →https://doi.org/10.1126/science.2468181openalex-snapshot
On Finding All Suboptimal Foldings of an RNA Molecule
inferredcites →https://doi.org/10.1126/science.7809611openalex-snapshot
A Proficient Enzyme
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Structure-Based Design of Transcription Factors
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CRC Handbook of Chemistry and Physics
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CRC Handbook of Chemistry and Physics
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Theoretical and physical principles of organic reactivity

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

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Co-delivery of doxorubicin and DNAzyme using ZnO@polydopamine core-shell nanocomposites for chemo/gene/photothermal therapy
inferred← citeshttps://doi.org/10.1016/j.actbio.2023.05.042openalex-snapshot
A smart metal-polyphenol-DNAzyme nanoplatform for gene-chemodynamic synergistic tumor therapy
inferred← citeshttps://doi.org/10.1016/j.addr.2021.05.018openalex-snapshot
Non-viral nanoparticles for RNA interference: Principles of design and practical guidelines
inferred← citeshttps://doi.org/10.1016/j.anndiagpath.2026.152681openalex-snapshot
Determinants of nucleic acid quality in formalin-fixed paraffin-embedded bladder urothelial carcinoma specimens: effects of specimen type, fixation conditions, and storage time
inferred← citeshttps://doi.org/10.1016/j.apsb.2022.08.013openalex-snapshot
Smart drug delivery systems for precise cancer therapy
inferred← citeshttps://doi.org/10.1016/j.bbapap.2015.04.022openalex-snapshot
Integration of kinetic isotope effect analyses to elucidate ribonuclease mechanism
inferred← citeshttps://doi.org/10.1016/j.bbrc.2005.03.161openalex-snapshot
tRNAPhe cleavage by aminoglycosides is triggered off by formation of an abasic site
inferred← citeshttps://doi.org/10.1016/j.bbrc.2019.05.162openalex-snapshot
Crystal structures of phage NrS-1 N300-dNTPs-Mg2+ complex provide molecular mechanisms for substrate specificity
inferred← citeshttps://doi.org/10.1016/j.bbrc.2025.152347openalex-snapshot
Exploring the future of mRNA delivery: Beyond lipid nanoparticles
inferred← citeshttps://doi.org/10.1016/j.bdq.2015.09.002openalex-snapshot
Differential amplicons (ΔAmp)—a new molecular method to assess RNA integrity
inferred← citeshttps://doi.org/10.1016/j.biochi.2007.12.007openalex-snapshot
A comparative analysis of CCA-adding enzymes from human and E. coli: Differences in CCA addition and tRNA 3′-end repair
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2019.119535openalex-snapshot
Cationic copolymer-chaperoned DNAzyme sensor for microRNA detection
inferred← citeshttps://doi.org/10.1016/j.biomaterials.2022.121570openalex-snapshot
An imidazole modified lipid confers enhanced mRNA-LNP stability and strong immunization properties in mice and non-human primates
inferred← citeshttps://doi.org/10.1016/j.bios.2020.112285openalex-snapshot
Selection of a metal ligand modified DNAzyme for detecting Ni2+
inferred← citeshttps://doi.org/10.1016/j.bios.2022.114423openalex-snapshot
Recent advance of RNA aptamers and DNAzymes for MicroRNA detection
inferred← citeshttps://doi.org/10.1016/j.biosystems.2026.105849openalex-snapshot
Protocode mats and living membranes: A new hypothesis for the origin of the standard genetic code
inferred← citeshttps://doi.org/10.1016/j.bmc.2020.115796openalex-snapshot
A new Pb2+-specific DNAzyme by revisiting the catalytic core of 10–23 DNAzyme
inferred← citeshttps://doi.org/10.1016/j.bmcl.2015.02.032openalex-snapshot
Tandem DNAzymes for mRNA cleavage: Choice of enzyme, metal ions and the antisense effect
inferred← citeshttps://doi.org/10.1016/j.bpc.2015.07.001openalex-snapshot
Determination of pKa values for deprotonable nucleobases in short model oligonucleotides
inferred← citeshttps://doi.org/10.1016/j.bpj.2017.07.013openalex-snapshot
The Incorporation of Ribonucleotides Induces Structural and Conformational Changes in DNA
inferred← citeshttps://doi.org/10.1016/j.carbpol.2014.03.046openalex-snapshot
Polysaccharide purification from Haemophilus influenzae type b through tangential microfiltration
inferred← citeshttps://doi.org/10.1016/j.carbpol.2014.04.004openalex-snapshot
Study of the chemical stability of the capsular polysaccharide produced by Haemophilus influenzae type b
inferred← citeshttps://doi.org/10.1016/j.cbpa.2004.02.006openalex-snapshot
Synthetic metallonucleases for RNA cleavage
inferred← citeshttps://doi.org/10.1016/j.cbpa.2005.10.004openalex-snapshot
Chemical models for ribozyme action
inferred← citeshttps://doi.org/10.1016/j.cbpb.2024.111036openalex-snapshot
Commentary: Environmental RNA and the assessment of organismal function in the field
inferred← citeshttps://doi.org/10.1016/j.ccr.2020.213624openalex-snapshot
Phosphorothioate nucleic acids for probing metal binding, biosensing and nanotechnology
inferred← citeshttps://doi.org/10.1016/j.ccr.2022.214453openalex-snapshot
Functional nucleic acid-based fluorescent probes for metal ion detection
inferred← citeshttps://doi.org/10.1016/j.cej.2026.182198openalex-snapshot
A nanotechnology-enhanced workflow for direct, sensitive detection of viral RNA in exhaled breath
inferred← citeshttps://doi.org/10.1016/j.cell.2007.06.051openalex-snapshot
Structure and Mechanism of a Metal-Sensing Regulatory RNA
inferred← citeshttps://doi.org/10.1016/j.cell.2012.04.011openalex-snapshot
Enzymatic Removal of Ribonucleotides from DNA Is Essential for Mammalian Genome Integrity and Development
inferred← citeshttps://doi.org/10.1016/j.cell.2014.04.015openalex-snapshot
Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome
inferred← citeshttps://doi.org/10.1016/j.celrep.2022.111448openalex-snapshot
Molecular basis for processing of topoisomerase 1-triggered DNA damage by Apn2/APE2
inferred← citeshttps://doi.org/10.1016/j.chembiol.2003.12.012openalex-snapshot
Dinucleotide Junction Cleavage Versatility of 8-17 Deoxyribozyme
inferred← citeshttps://doi.org/10.1016/j.chembiol.2009.01.008openalex-snapshot
Biologically Inspired Synthetic Enzymes Made from DNA
inferred← citeshttps://doi.org/10.1016/j.chemosphere.2022.134239openalex-snapshot
Environmental RNA outperforms eDNA metabarcoding in assessing impact of marine pollution: A chromium-spiked mesocosm test
inferred← citeshttps://doi.org/10.1016/j.chroma.2024.464885openalex-snapshot
Comprehensive chromatographic assessment of forced degraded in vitro transcribed mRNA
inferred← citeshttps://doi.org/10.1016/j.chroma.2026.467336openalex-snapshot
Prebiotic chemistry analysis with UHPLCOrbitrap MS: Optimizing protocols to detect ribose, nucleobases, nucleosides, nucleotides, and short RNA oligomers
inferred← citeshttps://doi.org/10.1016/j.compbiolchem.2005.04.009openalex-snapshot
Modelling molecular stability in the RNA world
inferred← citeshttps://doi.org/10.1016/j.csbj.2022.08.008openalex-snapshot
The life and death of RNA across temperatures
inferred← citeshttps://doi.org/10.1016/j.dnarep.2014.03.029openalex-snapshot
Ribonucleotides in DNA: Origins, repair and consequences
inferred← citeshttps://doi.org/10.1016/j.dnarep.2017.02.016openalex-snapshot
The role of RNase H2 in processing ribonucleotides incorporated during DNA replication
inferred← citeshttps://doi.org/10.1016/j.dnarep.2017.06.004openalex-snapshot
Genome instabilities arising from ribonucleotides in DNA
inferred← citeshttps://doi.org/10.1016/j.dnarep.2019.06.007openalex-snapshot
RADAR-seq: A RAre DAmage and Repair sequencing method for detecting DNA damage on a genome-wide scale
inferred← citeshttps://doi.org/10.1016/j.dnarep.2021.103198openalex-snapshot
How DNA damage and non-canonical nucleotides alter the telomerase catalytic cycle
inferred← citeshttps://doi.org/10.1016/j.dnarep.2022.103286openalex-snapshot
Facile preparation of model DNA interstrand cross-link repair intermediates using ribonucleotide-containing DNA
inferred← citeshttps://doi.org/10.1016/j.ecolind.2025.114328openalex-snapshot
Environmental RNA as a transformative tool for aquatic ecosystem health assessment: progress and challenges
inferred← citeshttps://doi.org/10.1016/j.ejps.2025.107183openalex-snapshot
Advancing continuous encapsulation and purification of mRNA vaccines and therapeutics
inferred← citeshttps://doi.org/10.1016/j.eurpolymj.2025.114294openalex-snapshot
Nucleic acid–inspired phosphorus-containing polymers
inferred← citeshttps://doi.org/10.1016/j.fmre.2026.03.015openalex-snapshot
Discovery of RNA-cleaving DNAzymes: Recent advancements, new functions and practical applications
inferred← citeshttps://doi.org/10.1016/j.foodchem.2025.145443openalex-snapshot
A comprehensive approach to the chemical analysis of fungal biomass – the pitfalls of nutritional standardization
inferred← citeshttps://doi.org/10.1016/j.gecco.2024.e02888openalex-snapshot
Evaluating the effectiveness of the eRNA technique in monitoring fish biodiversity – A case study in the Qingdao offshore, China
inferred← citeshttps://doi.org/10.1016/j.gene.2005.11.030openalex-snapshot
In vitro selection of halo-thermophilic RNA reveals two families of resistant RNA
inferred← citeshttps://doi.org/10.1016/j.gene.2011.05.017openalex-snapshot
An inhibitor of eIF2 activity in the sRNA pool of eukaryotic cells
inferred← citeshttps://doi.org/10.1016/j.idairyj.2026.106743openalex-snapshot
Optimised preparation of α-ribazole standards to support cyanide-free vitamin B12 analysis in infant formula
inferred← citeshttps://doi.org/10.1016/j.indcrop.2018.07.078openalex-snapshot
Hydroxypropyl sulfonated kraft lignin as a coagulant for cationic dye
inferred← citeshttps://doi.org/10.1016/j.intimp.2025.115339openalex-snapshot
Aptamers as immune checkpoint inhibitors in cancer immunotherapy: targeting CTLA-4/B7 and PD-1/PD-L1 pathways
inferred← citeshttps://doi.org/10.1016/j.jcis.2022.07.023openalex-snapshot
Artificial phosphatase upon premicellar nanoarchitectonics of lanthanum complexes with long-chained imidazole derivatives
inferred← citeshttps://doi.org/10.1016/j.jcis.2025.138161openalex-snapshot
Direct visual proof for the micellar solubilization of RNA models during its transesterification
inferred← citeshttps://doi.org/10.1016/j.jconrel.2025.114198openalex-snapshot
Pulmonary delivery of small circular RNA vaccines for influenza prevention
inferred← citeshttps://doi.org/10.1016/j.jmb.2004.06.027openalex-snapshot
Deprotonation Stimulates Productive Folding in Allosteric TRAP Hammerhead Ribozymes
inferred← citeshttps://doi.org/10.1016/j.jmb.2005.04.005openalex-snapshot
Role of an Active Site Adenine in Hairpin Ribozyme Catalysis
inferred← citeshttps://doi.org/10.1016/j.jmb.2010.05.047openalex-snapshot
A Complex RNA-Cleaving DNAzyme That Can Efficiently Cleave a Pyrimidine–Pyrimidine Junction
inferred← citeshttps://doi.org/10.1016/j.jmb.2017.08.004openalex-snapshot
RNase HII Saves rnhA Mutant Escherichia coli from R-Loop-Associated Chromosomal Fragmentation
inferred← citeshttps://doi.org/10.1016/j.jmb.2018.05.046openalex-snapshot
Peptide Amyloids in the Origin of Life
inferred← citeshttps://doi.org/10.1016/j.jmb.2020.05.003openalex-snapshot
Discovery of ANTAR-RNAs and their Mechanism of Action in Mycobacteria
inferred← citeshttps://doi.org/10.1016/j.jtbi.2021.110822openalex-snapshot
Rolling-circle and strand-displacement mechanisms for non-enzymatic RNA replication at the time of the origin of life
inferred← citeshttps://doi.org/10.1016/j.jviromet.2023.114733openalex-snapshot
β-Propiolactone (BPL)-inactivation of SARS-Co-V-2: In vitro validation with focus on saliva from COVID-19 patients for scent dog training
inferred← citeshttps://doi.org/10.1016/j.jviromet.2025.115169openalex-snapshot
Room temperature storage and shipping of encapsulated synthetic RNAs as quality control materials for SARS-CoV-2 molecular diagnostic assays
inferred← citeshttps://doi.org/10.1016/j.lwt.2019.01.040openalex-snapshot
Solubility of extracted proteins from Chlorella sorokiniana, Phaeodactylum tricornutum, and Nannochloropsis oceanica: Impact of pH-value
inferred← citeshttps://doi.org/10.1016/j.mehy.2005.04.038openalex-snapshot
Does the cell-brain theory work in explaining carcinogenesis?
inferred← citeshttps://doi.org/10.1016/j.mito.2021.10.005openalex-snapshot
The integrity and assay performance of tissue mitochondrial DNA is considerably affected by choice of isolation method
inferred← citeshttps://doi.org/10.1016/j.molcel.2015.02.009openalex-snapshot
Bacterial Riboswitches Cooperatively Bind Ni 2+ or Co 2+ Ions and Control Expression of Heavy Metal Transporters
inferred← citeshttps://doi.org/10.1016/j.molliq.2022.120097openalex-snapshot
To probe the binding of TMPyP4 to c-MYC G-quadruplex with in water and in imidazolium-based ionic liquids using spectroscopy coupled with molecular dynamics simulations
inferred← citeshttps://doi.org/10.1016/j.omtn.2026.102960openalex-snapshot
Fine-scale structural information substantially improves mRNA therapeutic stability prediction
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2015.11.001openalex-snapshot
Is the role of human RNase H2 restricted to its enzyme activity?
inferred← citeshttps://doi.org/10.1016/j.pbiomolbio.2026.02.006openalex-snapshot
Developing artificial cytoskeletons using RNA origami-based nanotubes
inferred← citeshttps://doi.org/10.1016/j.resmic.2015.08.006openalex-snapshot
Mismatch repair in Gram-positive bacteria
inferred← citeshttps://doi.org/10.1016/j.sbi.2005.05.002openalex-snapshot
Structure, folding and mechanisms of ribozymes
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2019.135314openalex-snapshot
Release and degradation of environmental DNA and RNA in a marine system
inferred← citeshttps://doi.org/10.1016/j.scitotenv.2021.146891openalex-snapshot
Environmental DNA and environmental RNA: Current and prospective applications for biological monitoring
inferred← citeshttps://doi.org/10.1016/j.talanta.2019.120709openalex-snapshot
Nucleic acid-cleaving catalytic DNA for sensing and therapeutics
inferred← citeshttps://doi.org/10.1016/j.talanta.2025.128586openalex-snapshot
Selection, characterization and the application of the RNA aptamer in the capture assay of Erythropoietin (EPO)
inferred← citeshttps://doi.org/10.1016/j.tet.2017.01.043openalex-snapshot
Synthesis and properties of cross-linkable DNA duplex using 4-amino-2-oxo-6-vinyl-1,3,5-triazine
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