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Iberian Pig as a Model To Clarify Obscure Points in the Bioavailability and Metabolism of Ellagitannins in Humans

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What this work says

Outgoing claims: the papers this work cites, builds on, or argues with.

inferredcites →https://doi.org/10.1002/jsfa.1017openalex-snapshot
Composition of subcutaneous fat from dry‐cured Iberian hams as influenced by pig feeding
inferredcites →https://doi.org/10.1007/s00394-003-0396-4openalex-snapshot
Evaluation of the bioavailability and metabolism in the rat of punicalagin, an antioxidant polyphenol from pomegranate juice
inferredcites →https://doi.org/10.1007/s00394-004-0461-7openalex-snapshot
The potent in vitro antioxidant ellagitannins from pomegranate juice are metabolised into bioavailable but poor antioxidant hydroxy?6H?dibenzopyran?6? one derivatives by the colonic microflora of healthy humans
inferredcites →https://doi.org/10.1016/j.cccn.2004.04.029openalex-snapshot
Bioavailability of ellagic acid in human plasma after consumption of ellagitannins from pomegranate (Punica granatum L.) juice
inferredcites →https://doi.org/10.1016/j.jnutbio.2005.09.004openalex-snapshot
The dietary hydrolysable tannin punicalagin releases ellagic acid that induces apoptosis in human colon adenocarcinoma Caco-2 cells by using the mitochondrial pathway
inferredcites →https://doi.org/10.1016/s0031-9422(03)00333-9openalex-snapshot
Antioxidative polyphenols from walnuts (Juglans regia L.)
inferredcites →https://doi.org/10.1021/jf000404aopenalex-snapshot
Antioxidant Activity of Pomegranate Juice and Its Relationship with Phenolic Composition and Processing
inferredcites →https://doi.org/10.1021/jf010192xopenalex-snapshot
Effect of Processing and Storage on the Antioxidant Ellagic Acid Derivatives and Flavonoids of Red Raspberry (Rubus idaeus) Jams
inferredcites →https://doi.org/10.1021/jf020842copenalex-snapshot
Repeated Oral Administration of High Doses of the Pomegranate Ellagitannin Punicalagin to Rats for 37 Days Is Not Toxic
inferredcites →https://doi.org/10.1021/jf030216vopenalex-snapshot
Phenolic Compounds and Fatty Acids from Acorns (Quercus spp.), the Main Dietary Constituent of Free-Ranged Iberian Pigs
inferredcites →https://doi.org/10.1021/jf049144dopenalex-snapshot
Metabolism of Antioxidant and Chemopreventive Ellagitannins from Strawberries, Raspberries, Walnuts, and Oak-Aged Wine in Humans: Identification of Biomarkers and Individual Variability
inferredcites →https://doi.org/10.1021/jf050377uopenalex-snapshot
Rapid Liquid Chromatography Tandem Mass Spectrometry Assay To Quantify Plasma (−)-Epicatechin Metabolites after Ingestion of a Standard Portion of Cocoa Beverage in Humans
inferredcites →https://doi.org/10.1021/jf050384iopenalex-snapshot
Identification of Urolithin A as a Metabolite Produced by Human Colon Microflora from Ellagic Acid and Related Compounds
inferredcites →https://doi.org/10.1021/jf0527403openalex-snapshot
Urolithins, Ellagic Acid-Derived Metabolites Produced by Human Colonic Microflora, Exhibit Estrogenic and Antiestrogenic Activities
inferredcites →https://doi.org/10.1021/jf061674hopenalex-snapshot
Absorption, Metabolism, and Antioxidant Effects of Pomegranate (Punica granatum L.) Polyphenols after Ingestion of a Standardized Extract in Healthy Human Volunteers
inferredcites →https://doi.org/10.1038/sj.ejcn.1602309openalex-snapshot
Pomegranate juice supplementation in chronic obstructive pulmonary disease: a 5-week randomized, double-blind, placebo-controlled trial
inferredcites →https://doi.org/10.1055/s-0029-1243114openalex-snapshot
Hyaluronidase Inhibitory Active 6H-Dibenzo[b,d]pyran-6-ones from the Feces ofTrogopterus xanthipes
inferredcites →https://doi.org/10.1093/ajcn/71.5.1062openalex-snapshot
Pomegranate juice consumption reduces oxidative stress, atherogenic modifications to LDL, and platelet aggregation: studies in humans and in atherosclerotic apolipoprotein E–deficient mice
inferredcites →https://doi.org/10.1093/jn/135.7.1718openalex-snapshot
Tissue Distribution of Quercetin in Rats and Pigs
inferredcites →https://doi.org/10.1093/jn/136.10.2481openalex-snapshot
Pomegranate Juice Ellagitannin Metabolites Are Present in Human Plasma and Some Persist in Urine for Up to 48 Hours
inferredcites →https://doi.org/10.1177/0091270005279636openalex-snapshot
Pharmacokinetics of Anthocyanins and Ellagic Acid in Healthy Volunteers Fed Freeze‐Dried Black Raspberries Daily for 7 Days
inferredcites →https://doi.org/10.1207/s15327914nc5401_8openalex-snapshot
Molecular Mechanisms Involved in Chemoprevention of Black Raspberry Extracts: From Transcription Factors to Their Target Genes

What points at this work

Incoming claims: where this work appears in other papers’ reference lists and arguments.

inferred← citeshttps://doi.org/10.1016/j.phytochem.2021.112799zenodo-depositor-declared
An overview on the role of plant-derived tannins for the treatment of lung cancer
inferred← citeshttps://doi.org/10.1002/9781119158042.ch13openalex-snapshot
Tannins in Fruits and Vegetables: Chemistry and Biological Functions
inferred← citeshttps://doi.org/10.1002/9781119563754.ch9openalex-snapshot
Ellagitannins and Their Gut Microbiota‐Derived Metabolites: Urolithins
inferred← citeshttps://doi.org/10.1002/9781444323375.ch4openalex-snapshot
Ellagitannins – An Underestimated Class of Plant Polyphenols: Chemical Reactivity ofC‐Glucosidic Ellagitannins in Relation to Wine Chemistry and Biological Activity
inferred← citeshttps://doi.org/10.1002/9783527626588.ch29openalex-snapshot
Tannins: Bioavailability and Mechanisms of Action
inferred← citeshttps://doi.org/10.1002/bab.2288openalex-snapshot
Ellagic acid as a potent anticancer drug: A comprehensive review on in vitro, in vivo, in silico, and drug delivery studies
inferred← citeshttps://doi.org/10.1002/cbdv.202300646openalex-snapshot
Combined Metabolite Analysis and Network Pharmacology to Elucidate the Mechanisms of Therapeutic Effect of Melastoma dodecandrum Ellagitannins on Abnormal Uterine Bleeding
inferred← citeshttps://doi.org/10.1002/cbdv.202500105openalex-snapshot
Clinical and Mechanistic Exploration of Ellagic Acid in Neurodegenerative Diseases: Targeted Neuroprotection Through Cellular and Molecular Mechanisms
inferred← citeshttps://doi.org/10.1002/fft2.70376openalex-snapshot
Beneficial Role of Natural Polyphenols Against Epilepsy: Greasing the Wheels of Pharmacotherapy Research for Epilepsy
inferred← citeshttps://doi.org/10.1002/fsn3.26openalex-snapshot
Polyphenols are responsible for the proapoptotic properties of pomegranate juice on leukemia cell lines
inferred← citeshttps://doi.org/10.1002/fsn3.601openalex-snapshot
Guava leaf extract suppresses osteoarthritis progression in a rat anterior cruciate ligament transection model
inferred← citeshttps://doi.org/10.1002/hc.21133openalex-snapshot
Synthesis and Self‐Assembled Helical Supramolecular Polymer of Ethyl 7,8‐dihydro‐3‐hydroxy‐9‐methyl‐7‐(4′‐nitrophenyl)‐6H‐dibenzo[c]‐ pyran‐6‐one‐8‐carboxylate
inferred← citeshttps://doi.org/10.1002/jcsm.12190openalex-snapshot
Urolithin B, a newly identified regulator of skeletal muscle mass
inferred← citeshttps://doi.org/10.1002/jsfa.6603openalex-snapshot
Quantification of γ ‐ and α ‐tocopherol isomers in combination with pattern recognition model as a tool for differentiating dry‐cured shoulders of Iberian pigs raised on different feeding systems
inferred← citeshttps://doi.org/10.1002/mnfr.200900152openalex-snapshot
Occurrence of urolithins, gut microbiota ellagic acid metabolites and proliferation markers expression response in the human prostate gland upon consumption of walnuts and pomegranate juice
inferred← citeshttps://doi.org/10.1002/mnfr.201100140openalex-snapshot
Metabolites and tissue distribution of resveratrol in the pig
inferred← citeshttps://doi.org/10.1002/mnfr.201100677openalex-snapshot
Ellagitannin metabolites, urolithin A glucuronide and its aglycone urolithin A , ameliorate TNF ‐α‐induced inflammation and associated molecular markers in human aortic endothelial cells
inferred← citeshttps://doi.org/10.1002/mnfr.201300931openalex-snapshot
Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients
inferred← citeshttps://doi.org/10.1002/mnfr.201500227openalex-snapshot
Effect of daily intake of pomegranate juice on fecal microbiota and feces metabolites from healthy volunteers
inferred← citeshttps://doi.org/10.1002/mnfr.201500264openalex-snapshot
Urolithins, gut microbiota‐derived metabolites of ellagitannins, inhibit LPS‐induced inflammation in RAW 264.7 murine macrophages
inferred← citeshttps://doi.org/10.1002/mnfr.201500470openalex-snapshot
The ellagitannin colonic metabolite urolithin D selectively inhibits EphA2 phosphorylation in prostate cancer cells
inferred← citeshttps://doi.org/10.1002/mnfr.201500796openalex-snapshot
Urolithin A, C, and D, but not iso‐urolithin A and urolithin B, attenuate triglyceride accumulation in human cultures of adipocytes and hepatocytes
inferred← citeshttps://doi.org/10.1002/mnfr.201500901openalex-snapshot
Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status
inferred← citeshttps://doi.org/10.1002/mnfr.201501060openalex-snapshot
Identification of gut‐derived metabolites of maslinic acid, a bioactive compound from Olea europaea L
inferred← citeshttps://doi.org/10.1002/mnfr.201600169openalex-snapshot
Pomegranate extract prevents skeletal muscle of mice against wasting induced by acute TNF‐α injection
inferred← citeshttps://doi.org/10.1002/mnfr.201700401openalex-snapshot
Pomegranate By‐Products in Colorectal Cancer Chemoprevention: Effects in Apc‐Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo
inferred← citeshttps://doi.org/10.1002/mnfr.202000129openalex-snapshot
Inhibition of 5‐Lipoxygenase‐Derived Leukotrienes and Hemiketals as a Novel Anti‐Inflammatory Mechanism of Urolithins
inferred← citeshttps://doi.org/10.1002/mnfr.202101019openalex-snapshot
Urolithins: a Comprehensive Update on their Metabolism, Bioactivity, and Associated Gut Microbiota
inferred← citeshttps://doi.org/10.1002/mnfr.202300009openalex-snapshot
Physiologically‐Based Pharmacokinetic Modeling of the Postbiotic Supplement Urolithin A Predicts its Bioavailability Is Orders of Magnitude Lower than Concentrations that Induce Toxicity, but also Neuroprotective Effects
inferred← citeshttps://doi.org/10.1002/mnfr.70067openalex-snapshot
Evidence for a Modulatory Effect of a 12‐Week Pomegranate Juice Intervention on the Transcriptional Response in Inflammatory Bowel Disease Patients Reducing Fecal Calprotectin Levels: Findings From a Proof‐of‐Principle Study
inferred← citeshttps://doi.org/10.1002/ptr.5784openalex-snapshot
Anticancer Activity ofPunica granatum(Pomegranate): A Review
inferred← citeshttps://doi.org/10.1002/ptr.7307openalex-snapshot
Ellagitannins, promising pharmacological agents for the treatment of cancer stem cells
inferred← citeshttps://doi.org/10.1007/978-1-60761-627-6_30openalex-snapshot
Pomegranate
inferred← citeshttps://doi.org/10.1007/978-3-030-39855-2_13openalex-snapshot
Punica granatum L. Constituents for Cancer Prevention, Chemosensitisation and Therapeutic Treatment
inferred← citeshttps://doi.org/10.1007/978-3-030-81404-5_11-1openalex-snapshot
Ellagitannins
inferred← citeshttps://doi.org/10.1007/978-3-031-28109-9_11openalex-snapshot
Ellagitannins
inferred← citeshttps://doi.org/10.1007/978-3-031-59365-9_7openalex-snapshot
Polyphenols as Functional Foods and Nutraceuticals
inferred← citeshttps://doi.org/10.1007/978-3-031-81489-1_5openalex-snapshot
Bioavailability and Toxicity of Jaboticaba’s Minor Compounds
inferred← citeshttps://doi.org/10.1007/978-3-319-93701-4_61openalex-snapshot
Establishing EDI for a Clinical Trial of a Treatment for Chikungunya
inferred← citeshttps://doi.org/10.1007/978-981-13-1745-3_25-1openalex-snapshot
Dietary Ellagitannins
inferred← citeshttps://doi.org/10.1007/978-981-13-5874-6_9openalex-snapshot
Flavonoids as Potential Anticancer Agents in Clinics: Where Have We Reached So Far?
inferred← citeshttps://doi.org/10.1007/978-981-15-4148-3_25openalex-snapshot
Dietary Ellagitannins
inferred← citeshttps://doi.org/10.1007/s00204-022-03232-2openalex-snapshot
Urolithin A attenuates arsenic-induced gut barrier dysfunction
inferred← citeshttps://doi.org/10.1007/s00204-026-04485-xopenalex-snapshot
Human internal exposures to alternariol and its monomethyl ether are predicted below thresholds of in vitro toxicity by physiologically based kinetic modeling
inferred← citeshttps://doi.org/10.1007/s00394-013-0589-4openalex-snapshot
Phase-II metabolism limits the antiproliferative activity of urolithins in human colon cancer cells
inferred← citeshttps://doi.org/10.1007/s00394-015-0924-zopenalex-snapshot
Urolithin A causes p21 up-regulation in prostate cancer cells
inferred← citeshttps://doi.org/10.1007/s00436-013-3669-8openalex-snapshot
In vitro antiplasmodial activity of some medicinal plants of Burkina Faso
inferred← citeshttps://doi.org/10.1007/s00706-013-0949-zopenalex-snapshot
A DFT and PM6 study of free radical scavenging activity of ellagic acid
inferred← citeshttps://doi.org/10.1007/s10600-016-1536-4openalex-snapshot
Natural Dibenzo[b,d]Pyran-6-Ones: Structural Diversity and Biological Activity
inferred← citeshttps://doi.org/10.1007/s10637-017-0483-7openalex-snapshot
Urolithins impair cell proliferation, arrest the cell cycle and induce apoptosis in UMUC3 bladder cancer cells
inferred← citeshttps://doi.org/10.1007/s10895-018-2290-8openalex-snapshot
Urolithin B as a Simple, Selective, Fluorescent Probe for Sensing Iron(III) in Semi-Aqueous Solution
inferred← citeshttps://doi.org/10.1007/s10895-019-02475-0openalex-snapshot
Urolithin A and B Derivatives as ON-OFF Selective Fluorescent Sensors for Iron(III)
inferred← citeshttps://doi.org/10.1007/s11033-023-09112-xopenalex-snapshot
The urolithin B nanomicellar delivery system as an efficient selective anticancer compound
inferred← citeshttps://doi.org/10.1007/s11101-016-9464-2openalex-snapshot
Ellagitannin geraniin: a review of the natural sources, biosynthesis, pharmacokinetics and biological effects
inferred← citeshttps://doi.org/10.1007/s11224-019-1284-8openalex-snapshot
Ellagitannin derivatives and some conjugated metabolites: aqueous-DMSO proton affinities and acidity constants
inferred← citeshttps://doi.org/10.1007/s11483-009-9109-8openalex-snapshot
EPR Spin-Trapping and Spin-Probing Spectroscopy in Assessing Antioxidant Properties: Example on Extracts of Catkin, Leaves, and Spiny Burs of Castanea sativa
inferred← citeshttps://doi.org/10.1007/s12035-025-05541-wopenalex-snapshot
Neuroprotective Attributes of Gut-derived Urolithins in Parkinson’s Disease
inferred← citeshttps://doi.org/10.1007/s12161-015-0226-3openalex-snapshot
A New HPLC-PAD/HPLC-ESI-MS Method for the Analysis of Phytoestrogens Produced by Bacterial Metabolism
inferred← citeshttps://doi.org/10.1007/s12257-020-0149-8openalex-snapshot
Urolithin A Induces Brown-like Phenotype in 3T3-L1 White Adipocytes via β3-adrenergic Receptor-p38 MAPK Signaling Pathway
inferred← citeshttps://doi.org/10.1007/s12672-025-02444-zopenalex-snapshot
Urolithins’ interaction with hepatocyte growth factor receptor: a mechanistic basis for anticancer activity in gastric adenocarcinoma cells
inferred← citeshttps://doi.org/10.1007/s44174-025-00506-yopenalex-snapshot
Development of Ellagic- Acid Based Silver Doped Titanium Dioxide Nanoparticles Against Human A549 Cell Lines and Study of Their Mechanism at the Cellular Level
inferred← citeshttps://doi.org/10.1016/b978-0-12-407825-3.00006-xopenalex-snapshot
Bioactivation of High-Molecular-Weight Polyphenols by the Gut Microbiome
inferred← citeshttps://doi.org/10.1016/b978-0-12-812780-3.00034-9openalex-snapshot
Pomegranate
inferred← citeshttps://doi.org/10.1016/b978-0-443-21842-2.00009-7openalex-snapshot
Medicinal plants from the Mediterranean basin as a source of natural antiprostate cancer agents
inferred← citeshttps://doi.org/10.1016/b978-0-444-64181-6.00006-1openalex-snapshot
Sources, Chemistry, and Biological Potential of Ellagitannins and Ellagic Acid Derivatives
inferred← citeshttps://doi.org/10.1016/bs.aambs.2024.02.007openalex-snapshot
Effects of gut bacteria and their metabolites on gut health of animals
inferred← citeshttps://doi.org/10.1016/j.abb.2016.02.017openalex-snapshot
Antiatherogenic effects of ellagic acid and urolithins in vitro
inferred← citeshttps://doi.org/10.1016/j.arr.2024.102406openalex-snapshot
Targeting aging with urolithin A in humans: A systematic review
inferred← citeshttps://doi.org/10.1016/j.bbalip.2018.05.009openalex-snapshot
Ellagic acid protects from myelin-associated sphingolipid loss in experimental autoimmune encephalomyelitis
inferred← citeshttps://doi.org/10.1016/j.biopha.2008.07.093openalex-snapshot
Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells
inferred← citeshttps://doi.org/10.1016/j.biopha.2021.112314openalex-snapshot
Jaboticaba (Myrciaria jaboticaba) powder consumption improves the metabolic profile and regulates gut microbiome composition in high-fat diet-fed mice
inferred← citeshttps://doi.org/10.1016/j.biopha.2025.118058openalex-snapshot
Urolithins: Emerging natural compound targeting castration-resistant prostate cancer (CRPC)
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An integrated green biorefinery approach towards simultaneous recovery of pectin and polyphenols coupled with bioethanol production from waste pomegranate peels
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Multitargeted therapy of cancer by ellagitannins
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Encapsulated urolithin B–methyl-β-cyclodextrin inclusion complex: Synthesis, characterization, in vivo pharmacokinetics with hypolipidemic effect
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Metabolite profiling analysis of FR429, an ellagitannin purified from Polygonum capitatum, in rat and human liver microsomes, cytosol and rat primary hepatocytes in vitro
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Chromatographic and spectroscopic characterization of urolithins for their determination in biological samples after the intake of foods containing ellagitannins and ellagic acid
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A comprehensive study of pomegranate flowers polyphenols and metabolites in rat biological samples by high-performance liquid chromatography quadrupole time-of-flight mass spectrometry
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Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review
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Constitutes, biofunctions and preparations of walnut polyphenols: A review
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Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar rats
inferred← citeshttps://doi.org/10.1016/j.fct.2016.03.011openalex-snapshot
In vivo relevant mixed urolithins and ellagic acid inhibit phenotypic and molecular colon cancer stem cell features: A new potentiality for ellagitannin metabolites against cancer
inferred← citeshttps://doi.org/10.1016/j.fct.2017.04.021openalex-snapshot
Galloylation of polyphenols alters their biological activity
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Dietary polyphenols: Structures, bioavailability and protective effects against atherosclerosis
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Urolithins, ellagitannin metabolites produced by colon microbiota, inhibit Quorum Sensing in Yersinia enterocolitica: Phenotypic response and associated molecular changes
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Hibiscus sabdariffa leaf polyphenolic extract inhibits LDL oxidation and foam cell formation involving up-regulation of LXRα/ABCA1 pathway
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Recyclable enzymatic recovery of pectin and punicalagin rich phenolics from waste pomegranate peels using magnetic nanobiocatalyst
inferred← citeshttps://doi.org/10.1016/j.foodhyd.2023.109221openalex-snapshot
Recent advances in the conjugation approaches for enhancing the bioavailability of polyphenols
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Ellagitannins, ellagic acid and their derived metabolites: A review about source, metabolism, functions and health
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Diversity of urinary excretion patterns of main ellagitannins' colonic metabolites after ingestion of tropical highland blackberry (Rubus adenotrichus) juice
inferred← citeshttps://doi.org/10.1016/j.foodres.2014.09.003openalex-snapshot
Profiling ellagic acid content: The importance of form and ascorbic acid levels
inferred← citeshttps://doi.org/10.1016/j.foodres.2018.03.023openalex-snapshot
Tea and coffee time with bacteria – Investigation of uptake of key coffee and tea phenolics by wild type E. coli
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LC-MS/MS based molecular networking approach for the identification of cocoa phenolic metabolites in human urine
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New insights into the bioavailability of red raspberry anthocyanins and ellagitannins
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A review: extraction, phytochemicals, and biological activities of rambutan (Nephelium lappaceum L) peel extract
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RETRACTED: Pomegranate-specific natural compounds as onco-preventive and onco-therapeutic compounds: Comparison with conventional drugs acting on the same molecular mechanisms
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Effect of chestnut tannin extract ( Castanea sativa Miller) on the proliferation of Cladosporium cladosporioides on sheep cheese rind during the ripening
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The influence of pomegranate by-product and punicalagins on selected groups of human intestinal microbiota
inferred← citeshttps://doi.org/10.1016/j.ijpharm.2024.124333openalex-snapshot
Enhancing the Bioavailability of the Ellagitannin, Geraniin: Formulation, Characterization, and in vivo Evaluation
inferred← citeshttps://doi.org/10.1016/j.jclepro.2019.04.392openalex-snapshot
Rapid, enhanced and eco-friendly recovery of punicalagin from fresh waste pomegranate peels via aqueous ball milling
inferred← citeshttps://doi.org/10.1016/j.jcmgh.2021.02.007openalex-snapshot
Regulation of Intestinal Barrier Function by Microbial Metabolites
inferred← citeshttps://doi.org/10.1016/j.jep.2014.06.032openalex-snapshot
Role of human gut microbiota metabolism in the anti-inflammatory effect of traditionally used ellagitannin-rich plant materials
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Lythrum salicaria L. herb and gut microbiota of healthy post-weaning piglets. Focus on prebiotic properties and formation of postbiotic metabolites in ex vivo cultures.
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A review of the traditional uses, phytochemistry and biological activities of the Melastoma genus
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The potential antidiabetic properties of green and purple tea [Camellia sinensis (L.) O Kuntze], purple tea ellagitannins, and urolithins
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Application of in vitro gastrointestinal digestion and colonic fermentation models to pomegranate products (juice, pulp and peel extract) to study the stability and catabolism of phenolic compounds
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Urolithins at physiological concentrations affect the levels of pro-inflammatory cytokines and growth factor in cultured cardiac cells in hyperglucidic conditions
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Identifying the limits for ellagic acid bioavailability: A crossover pharmacokinetic study in healthy volunteers after consumption of pomegranate extracts
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Phytoestrogen metabolism by lactic acid bacteria: Enterolignan production by Lactobacillus salivarius and Lactobacillus gasseri strains
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Metabolism of ellagitannins from jabuticaba (Myrciaria jaboticaba) in normoweight, overweight and obese Brazilians: Unexpected laxative effects influence urolithins urinary excretion and metabotype distribution
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Impact of ellagitannin-rich fruit consumption on blood pressure: A systematic review and meta-analysis of randomized controlled trials
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2009.04.012openalex-snapshot
Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2013.04.004openalex-snapshot
Ellagic acid inhibits PDGF-BB-induced vascular smooth muscle cell proliferation and prevents atheroma formation in streptozotocin-induced diabetic rats
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2013.05.001openalex-snapshot
Benefits of polyphenols on gut microbiota and implications in human health
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2015.02.003openalex-snapshot
White and dark kidney beans reduce colonic mucosal damage and inflammation in response to dextran sodium sulfate
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2015.10.014openalex-snapshot
Diets enriched with cranberry beans alter the microbiota and mitigate colitis severity and associated inflammation
inferred← citeshttps://doi.org/10.1016/j.jnutbio.2017.01.014openalex-snapshot
Gene expression changes in colon tissues from colorectal cancer patients following the intake of an ellagitannin-containing pomegranate extract: a randomized clinical trial
inferred← citeshttps://doi.org/10.1016/j.jpba.2012.07.028openalex-snapshot
Identification of metabolites of FR429, a potential antitumor ellagitannin, transformed by rat intestinal bacteria in vitro, based on liquid chromatography–ion trap-time of flight mass spectrometry analysis
inferred← citeshttps://doi.org/10.1016/j.jpba.2023.115914openalex-snapshot
Development and validation of a LC–MS/MS method for the quantification of phenolic compounds in human saliva after intake of a procyanidin-rich pine bark extract
inferred← citeshttps://doi.org/10.1016/j.livsci.2017.08.002openalex-snapshot
Effects of tannins on the fatty acid profiles of rumen fluids and milk from lactating goats fed a total mixed ration containing rapeseed oil
inferred← citeshttps://doi.org/10.1016/j.livsci.2020.104006openalex-snapshot
Effect of the Iberian pig rearing system on blood plasma antioxidant status and oxidative stress biomarkers
inferred← citeshttps://doi.org/10.1016/j.lwt.2017.06.029openalex-snapshot
Effect of ellagic acid incorporation on the oxidative stability of sodium caseinate-polysaccharide-stabilized emulsions
inferred← citeshttps://doi.org/10.1016/j.mam.2010.09.005openalex-snapshot
Ellagitannins, ellagic acid and vascular health
inferred← citeshttps://doi.org/10.1016/j.mam.2010.09.007openalex-snapshot
Bioavailability of dietary flavonoids and phenolic compounds
inferred← citeshttps://doi.org/10.1016/j.mam.2022.101109openalex-snapshot
Ellagitannins, urolithins, and neuroprotection: Human evidence and the possible link to the gut microbiota
inferred← citeshttps://doi.org/10.1016/j.numecd.2009.05.015openalex-snapshot
Polyphenols and health: What compounds are involved?
inferred← citeshttps://doi.org/10.1016/j.nut.2011.08.009openalex-snapshot
The strawberry: Composition, nutritional quality, and impact on human health
inferred← citeshttps://doi.org/10.1016/j.nut.2020.110973openalex-snapshot
Pleiotropic ameliorative effects of ellagitannin geraniin against metabolic syndrome induced by high-fat diet in rats
inferred← citeshttps://doi.org/10.1016/j.nutres.2016.10.003openalex-snapshot
Changes in intestinal immunity, gut microbiota, and expression of energy metabolism–related genes explain adenoma growth in bilberry and cloudberry-fed Apc Min mice
inferred← citeshttps://doi.org/10.1016/j.phrs.2015.04.008openalex-snapshot
Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection
inferred← citeshttps://doi.org/10.1016/j.phrs.2019.02.024openalex-snapshot
Gut microbiota, a new frontier to understand traditional Chinese medicines
inferred← citeshttps://doi.org/10.1016/j.phymed.2025.157292openalex-snapshot
Gut microbiota metabolite Urolithin B inhibits chondrocyte ferroptosis by rewriting iron homeostasis via FGFR3/NCOA4/FTH1 axis, alleviating osteoarthritis
inferred← citeshttps://doi.org/10.1016/j.phyplu.2022.100313openalex-snapshot
Advances towards the analysis, metabolism and health benefits of punicalagin, one of the largest ellagitannin from plants, with future perspectives
inferred← citeshttps://doi.org/10.1016/j.redox.2014.06.008openalex-snapshot
Wine consumption and intestinal redox homeostasis
inferred← citeshttps://doi.org/10.1016/j.sajb.2025.12.024openalex-snapshot
Geraniin as an antiviral agent: Chemistry and biological profiles, preventive and therapeutic effects on various viruses and associated molecular mechanisms
inferred← citeshttps://doi.org/10.1016/j.semcancer.2021.01.006openalex-snapshot
Pomegranate bioactive constituents target multiple oncogenic and oncosuppressive signaling for cancer prevention and intervention
inferred← citeshttps://doi.org/10.1016/j.tiv.2015.04.008openalex-snapshot
In vitro antiproliferative and antioxidant effects of urolithin A, the colonic metabolite of ellagic acid, on hepatocellular carcinomas HepG2 cells
inferred← citeshttps://doi.org/10.1017/s0007114510000826openalex-snapshot
NF-κB-dependent anti-inflammatory activity of urolithins, gut microbiota ellagic acid-derived metabolites, in human colonic fibroblasts
inferred← citeshttps://doi.org/10.1017/s0007114510003958openalex-snapshot
Berry flavonoids and phenolics: bioavailability and evidence of protective effects
inferred← citeshttps://doi.org/10.1017/s0007114512002206openalex-snapshot
Polyphenol-rich extract of pomegranate peel alleviates tissue inflammation and hypercholesterolaemia in high-fat diet-induced obese mice: potential implication of the gut microbiota
inferred← citeshttps://doi.org/10.1017/s0007114513004352openalex-snapshot
Cooked navy and black bean diets improve biomarkers of colon health and reduce inflammation during colitis
inferred← citeshttps://doi.org/10.1017/s1751731116002597openalex-snapshot
Hydrolysable tannin-based diet rich in gallotannins has a minimal impact on pig performance but significantly reduces salivary and bulbourethral gland size
inferred← citeshttps://doi.org/10.1017/s1751731119002143openalex-snapshot
Invited review: Tannins as a potential alternative to antibiotics to prevent coliform diarrhea in weaned pigs
inferred← citeshttps://doi.org/10.1021/acs.jafc.0c02674openalex-snapshot
Transformation of Oligomeric Ellagitannins, Typical for Rubus and Fragaria Genus, during Strong Acid Hydrolysis
inferred← citeshttps://doi.org/10.1021/acs.jafc.1c03521openalex-snapshot
Inhibitory Effects and Surface Plasmon Resonance-Based Binding Affinities of Dietary Hydrolyzable Tannins and Their Gut Microbial Metabolites on SARS-CoV-2 Main Protease
inferred← citeshttps://doi.org/10.1021/acs.jafc.3c09881openalex-snapshot
Chestnut Wood Tannins in Broiler Diets: Pharmacokinetics, Serum Levels during Rearing, and Intestinal Absorption Pattern of Gallic Acid
inferred← citeshttps://doi.org/10.1021/acs.jafc.5b00648openalex-snapshot
Chemical Composition of Defatted Strawberry and Raspberry Seeds and the Effect of These Dietary Ingredients on Polyphenol Metabolites, Intestinal Function, and Selected Serum Parameters in Rats
inferred← citeshttps://doi.org/10.1021/acs.jafc.7b01876openalex-snapshot
Chemical Composition of Blackberry Press Cake, Polyphenolic Extract, and Defatted Seeds, and Their Effects on Cecal Fermentation, Bacterial Metabolites, and Blood Lipid Profile in Rats
inferred← citeshttps://doi.org/10.1021/acs.jafc.7b02049openalex-snapshot
Gastrointestinal Simulation Model TWIN-SHIME Shows Differences between Human Urolithin-Metabotypes in Gut Microbiota Composition, Pomegranate Polyphenol Metabolism, and Transport along the Intestinal Tract
inferred← citeshttps://doi.org/10.1021/acs.jafc.7b02128openalex-snapshot
Edible Nanoencapsulation Vehicles for Oral Delivery of Phytochemicals: A Perspective Paper
inferred← citeshttps://doi.org/10.1021/acs.jafc.7b04120openalex-snapshot
Ellagitannins from Strawberries with Different Degrees of Polymerization Showed Different Metabolism through Gastrointestinal Tract of Rats
inferred← citeshttps://doi.org/10.1021/acs.jafc.8b03100openalex-snapshot
Physiological Relevance of the Antiproliferative and Estrogenic Effects of Dietary Polyphenol Aglycones versus Their Phase-II Metabolites on Breast Cancer Cells: A Call of Caution
inferred← citeshttps://doi.org/10.1021/acs.jafc.9b00222openalex-snapshot
Phenolic Metabolites in Plasma and Thigh Meat of Chickens Supplemented with Grape Byproducts
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.0c00776openalex-snapshot
Lythrum salicaria Ellagitannins Stimulate IPEC-J2 Cells Monolayer Formation and Inhibit Enteropathogenic Escherichia coli Growth and Adhesion
inferred← citeshttps://doi.org/10.1021/acs.jnatprod.6b00602openalex-snapshot
Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures
inferred← citeshttps://doi.org/10.1021/acschemneuro.5b00260openalex-snapshot
Pomegranate’s Neuroprotective Effects against Alzheimer’s Disease Are Mediated by Urolithins, Its Ellagitannin-Gut Microbial Derived Metabolites
inferred← citeshttps://doi.org/10.1021/acssuschemeng.8b03452openalex-snapshot
Complete Utilization of Waste Pomegranate Peels To Produce a Hydrocolloid, Punicalagin Rich Phenolics, and a Hard Carbon Electrode
inferred← citeshttps://doi.org/10.1021/bk-2018-1286.ch013openalex-snapshot
Encapsulation of Polyphenols: An Effective Way To Enhance Their Bioavailability for Gut Health
inferred← citeshttps://doi.org/10.1021/jf100315dopenalex-snapshot
Bioavailability of Anthocyanins and Ellagitannins Following Consumption of Raspberries by Healthy Humans and Subjects with an Ileostomy
inferred← citeshttps://doi.org/10.1021/jf102799mopenalex-snapshot
Pharmacokinetic Study of trans-Resveratrol in Adult Pigs
inferred← citeshttps://doi.org/10.1021/jf103894mopenalex-snapshot
UV and MS Identification of Urolithins and Nasutins, the Bioavailable Metabolites of Ellagitannins and Ellagic Acid in Different Mammals
inferred← citeshttps://doi.org/10.1021/jf203318popenalex-snapshot
The Blackberry Fruit: A Review on Its Composition and Chemistry, Metabolism and Bioavailability, and Health Benefits
inferred← citeshttps://doi.org/10.1021/jf203641ropenalex-snapshot
Strawberry Processing Does Not Affect the Production and Urinary Excretion of Urolithins, Ellagic Acid Metabolites, in Humans
inferred← citeshttps://doi.org/10.1021/jf300290fopenalex-snapshot
Intestinal Ellagitannin Metabolites Ameliorate Cytokine-Induced Inflammation and Associated Molecular Markers in Human Colon Fibroblasts
inferred← citeshttps://doi.org/10.1021/jf300718kopenalex-snapshot
Metabolism of Oak Leaf Ellagitannins and Urolithin Production in Beef Cattle
inferred← citeshttps://doi.org/10.1021/jf301509wopenalex-snapshot
Urolithins Are the Main Urinary Microbial-Derived Phenolic Metabolites Discriminating a Moderate Consumption of Nuts in Free-Living Subjects with Diagnosed Metabolic Syndrome
inferred← citeshttps://doi.org/10.1021/jf4007505openalex-snapshot
The Gut Microbiota Ellagic Acid-Derived Metabolite Urolithin A and Its Sulfate Conjugate Are Substrates for the Drug Efflux Transporter Breast Cancer Resistance Protein (ABCG2/BCRP)
inferred← citeshttps://doi.org/10.1021/jf402394copenalex-snapshot
Microbial Metabolomic Fingerprinting in Urine after Regular Dealcoholized Red Wine Consumption in Humans
inferred← citeshttps://doi.org/10.1021/jf403208dopenalex-snapshot
Urolithins Display both Antioxidant and Pro-oxidant Activities Depending on Assay System and Conditions
inferred← citeshttps://doi.org/10.1021/jf403493aopenalex-snapshot
Absorption, Metabolism, and Effects at Transcriptome Level of a Standardized French Oak Wood Extract, Robuvit, in Healthy Volunteers: Pilot Study
inferred← citeshttps://doi.org/10.1021/jf4038503openalex-snapshot
Ellagic Acid Identified through Metabolomic Analysis Is an Active Metabolite in Strawberry (‘Seolhyang’) Regulating Lipopolysaccharide-Induced Inflammation
inferred← citeshttps://doi.org/10.1021/jf404965zopenalex-snapshot
Modulation of Strawberry/Cranberry Phenolic Compounds Glucuronidation by Co-Supplementation with Onion: Characterization of Phenolic Metabolites in Rat Plasma Using an Optimized μSPE–UHPLC-MS/MS Method
inferred← citeshttps://doi.org/10.1021/jf405612aopenalex-snapshot
Strawberry Ellagitannins Thwarted the Positive Effects of Dietary Fructooligosaccharides in Rat Cecum
inferred← citeshttps://doi.org/10.1021/jf500106ropenalex-snapshot
Variability in the Antioxidant Activity of Dietary Supplements from Pomegranate, Milk Thistle, Green Tea, Grape Seed, Goji, and Acai: Effects of in Vitro Digestion
inferred← citeshttps://doi.org/10.1021/jf5040652openalex-snapshot
Pilot Walnut Intervention Study of Urolithin Bioavailability in Human Volunteers
inferred← citeshttps://doi.org/10.1021/jf8000857openalex-snapshot
Safety Evaluation of an Oak-Flavored Milk Powder Containing Ellagitannins upon Oral Administration in the Rat
inferred← citeshttps://doi.org/10.1021/jf803638dopenalex-snapshot
Effect of a Low Dose of Dietary Resveratrol on Colon Microbiota, Inflammation and Tissue Damage in a DSS-Induced Colitis Rat Model
inferred← citeshttps://doi.org/10.1021/jf900725eopenalex-snapshot
DissimilarIn VitroandIn VivoEffects of Ellagic Acid and Its Microbiota-Derived Metabolites, Urolithins, on the Cytochrome P450 1A1
inferred← citeshttps://doi.org/10.1021/jf902107dopenalex-snapshot
Interaction between Phenolics and Gut Microbiota: Role in Human Health
inferred← citeshttps://doi.org/10.1021/jf9025794openalex-snapshot
Urolithins, Intestinal Microbial Metabolites of Pomegranate Ellagitannins, Exhibit Potent Antioxidant Activity in a Cell-Based Assay
inferred← citeshttps://doi.org/10.1021/jf902857vopenalex-snapshot
Effects of Fruit Ellagitannin Extracts, Ellagic Acid, and Their Colonic Metabolite, Urolithin A, on Wnt Signaling
inferred← citeshttps://doi.org/10.1021/jf903161gopenalex-snapshot
Anticarcinogenic Effects of Polyphenolics from Mango (Mangifera indica) Varieties
inferred← citeshttps://doi.org/10.1021/jf904543wopenalex-snapshot
Profiling and Accurate Quantification of Rubus Ellagitannins and Ellagic Acid Conjugates Using Direct UPLC-Q-TOF HDMS and HPLC-DAD Analysis
inferred← citeshttps://doi.org/10.1021/jm1007006openalex-snapshot
Preventive Oral Treatment with Resveratrol Pro-prodrugs Drastically Reduce Colon Inflammation in Rodents
inferred← citeshttps://doi.org/10.1021/pr200514hopenalex-snapshot
Metabolomics Unveils Urinary Changes in Subjects with Metabolic Syndrome following 12-Week Nut Consumption
inferred← citeshttps://doi.org/10.1038/s41598-019-44390-1openalex-snapshot
Metabolomics reveals diet-derived plant polyphenols accumulate in physiological bone
inferred← citeshttps://doi.org/10.1038/s41598-025-10904-3openalex-snapshot
Efficacy of urolithin B-Loaded mesoporous silica nanoparticles modified with graphene quantum Dots against MCF-7 breast Cancer cells
inferred← citeshttps://doi.org/10.1039/b802662aopenalex-snapshot
Dietary phenolics: chemistry, bioavailability and effects on health
inferred← citeshttps://doi.org/10.1039/c2fo30034fopenalex-snapshot
Pomegranate: a fruit that ameliorates metabolic syndrome
inferred← citeshttps://doi.org/10.1039/c2fo30055aopenalex-snapshot
The combination of analytical-scale HPLC separation with a TR-FRET assay to investigate JAK2 inhibitory compounds in a Boysenberry drink
inferred← citeshttps://doi.org/10.1039/c4fo00092gopenalex-snapshot
Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter species
inferred← citeshttps://doi.org/10.1039/c4fo00670dopenalex-snapshot
Atheroprotective effects of (poly)phenols: a focus on cell cholesterol metabolism
inferred← citeshttps://doi.org/10.1039/c5fo00120jopenalex-snapshot
The ellagic acid-derived gut microbiota metabolite, urolithin A, potentiates the anticancer effects of 5-fluorouracil chemotherapy on human colon cancer cells
inferred← citeshttps://doi.org/10.1039/c5fo00274eopenalex-snapshot
Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells
inferred← citeshttps://doi.org/10.1039/c5fo90027aopenalex-snapshot
Correction: Chemopreventive activity of ellagitannins and their derivatives from black raspberry seeds on HT-29 colon cancer cells
inferred← citeshttps://doi.org/10.1039/c6fo00652copenalex-snapshot
Quantification of microbial uptake of quercetin and its derivatives using an UHPLC-ESI-QTOF mass spectrometry assay
inferred← citeshttps://doi.org/10.1039/c7ay02626aopenalex-snapshot
Historical mystery solved: a multi-analytical approach to the identification of a key marker for the historical use of brazilwood ( Caesalpinia spp.) in paintings and textiles
inferred← citeshttps://doi.org/10.1039/c7fo00076fopenalex-snapshot
Potential antiproliferative activity of polyphenol metabolites against human breast cancer cells and their urine excretion pattern in healthy subjects following acute intake of a polyphenol-rich juice of grumixama (Eugenia brasiliensis Lam.)
inferred← citeshttps://doi.org/10.1039/c7ra01548hopenalex-snapshot
Urolithin C, a gut metabolite of ellagic acid, induces apoptosis in PC12 cells through a mitochondria-mediated pathway
inferred← citeshttps://doi.org/10.1039/c9fo00218aopenalex-snapshot
Isoleucine attenuates infection induced by E. coli challenge through the modulation of intestinal endogenous antimicrobial peptide expression and the inhibition of the increase in plasma endotoxin and IL-6 in weaned pigs
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